TreeWAS – Variant ID: rs1956388

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H60.9 Otitis externa, unspecified	0.000	0.828	0.172
H60 Otitis externa	0.000	0.832	0.168
H60.1 Cellulitis of external ear	0.000	0.845	0.155
H60-H62 Diseases of external ear	0.000	0.858	0.142
H60.2 Malignant otitis externa	0.000	0.865	0.135
H61 Other disorders of external ear	0.000	0.865	0.135
H60.8 Other otitis externa	0.000	0.866	0.133
H60.5 Acute otitis externa, non-infective	0.000	0.867	0.133
H61.8 Other specified disorders of external ear	0.000	0.873	0.127
H60.0 Abscess of external ear	0.000	0.873	0.126
H61.0 Perichondritis of external ear	0.000	0.884	0.116
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.886	0.114
H61.3 Acquired stenosis of external ear canal	0.000	0.887	0.113
H61.9 Disorder of external ear, unspecified	0.000	0.893	0.107
H60.3 Other infective otitis externa	0.000	0.893	0.107
H60.4 Cholesteatoma of external ear	0.000	0.895	0.105
H61.1 Non-infective disorders of pinna	0.000	0.905	0.095
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.906	0.094
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.918	0.082
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.918	0.082
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.918	0.082
H62.2 Otitis externa in mycoses	0.000	0.918	0.082
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.918	0.082
F32.2 Severe depressive episode without psychotic symptoms	0.075	0.925	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.960	0.040
N31.8 Other neuromuscular dysfunction of bladder	0.039	0.961	0.000
F32 Depressive episode	0.037	0.963	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.033	0.967	0.000
F32.0 Mild depressive episode	0.031	0.969	0.000
F32.1 Moderate depressive episode	0.029	0.971	0.000
F32.8 Other depressive episodes	0.025	0.975	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.019	0.981	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.019	0.981	0.000
H61.2 Impacted cerumen	0.000	0.981	0.019
C34.1 Upper lobe, bronchus or lung	0.000	0.985	0.015
Y44.2 Anticoagulants	0.000	0.986	0.014
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.986	0.014
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.014	0.986	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.014	0.986	0.000
C32.9 Larynx, unspecified	0.000	0.987	0.013
N95.2 Postmenopausal atrophic vaginitis	0.000	0.987	0.013
C32 Malignant neoplasm of larynx	0.000	0.988	0.012
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.012	0.988	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.988	0.012
T93 Sequelae of injuries of lower limb	0.012	0.988	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.000	0.988	0.012
R26.0 Ataxic gait	0.000	0.989	0.011
C34.3 Lower lobe, bronchus or lung	0.000	0.989	0.011
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.011	0.989	0.000
R29.0 Tetany	0.000	0.989	0.011
T93.9 Sequelae of unspecified injury of lower limb	0.011	0.989	0.000
R29.4 Clicking hip	0.000	0.990	0.010
R29.3 Abnormal posture	0.000	0.990	0.010
T93.0 Sequelae of open wound of lower limb	0.010	0.990	0.000
R26 Abnormalities of gait and mobility	0.000	0.990	0.010
T93.8 Sequelae of other specified injuries of lower limb	0.010	0.990	0.000
C32.1 Supraglottis	0.000	0.990	0.010
C32.0 Glottis	0.000	0.990	0.010
C38 Malignant neoplasm of heart, mediastinum and pleura	0.000	0.990	0.009
R26.3 Immobility	0.000	0.990	0.010
R29.2 Abnormal reflex	0.000	0.991	0.009
C37 Malignant neoplasm of thymus	0.000	0.991	0.009
C32.8 Overlapping lesion of larynx	0.000	0.991	0.009
C32.3 Laryngeal cartilage	0.000	0.991	0.009
C32.2 Subglottis	0.000	0.991	0.009
C33 Malignant neoplasm of trachea	0.000	0.991	0.009
C30 Malignant neoplasm of nasal cavity and middle ear	0.000	0.991	0.009
C34.2 Middle lobe, bronchus or lung	0.000	0.991	0.009
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.009	0.991	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.009	0.991	0.000
Z50.1 Other physical therapy	0.000	0.991	0.009
G45.4 Transient global amnesia	0.009	0.991	0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.000	0.991	0.009
C31 Malignant neoplasm of accessory sinuses	0.000	0.991	0.009
T93.2 Sequelae of other fractures of lower limb	0.009	0.991	0.000
R29.1 Meningismus	0.000	0.991	0.008
T93.1 Sequelae of fracture of femur	0.008	0.991	0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.000	0.992	0.008
C38.4 Pleura	0.000	0.992	0.008
R01.1 Cardiac murmur, unspecified	0.008	0.992	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.992	0.008
R26.1 Paralytic gait	0.000	0.992	0.008
C34.8 Overlapping lesion of bronchus and lung	0.000	0.992	0.007
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.993	0.007
C30.0 Nasal cavity	0.000	0.993	0.007
C38.8 Overlapping lesion of heart, mediastinum and pleura	0.000	0.993	0.007
C38.2 Posterior mediastinum	0.000	0.993	0.007
C38.1 Anterior mediastinum	0.000	0.993	0.007
C38.0 Heart	0.000	0.993	0.007
R29.6 Tendency to fall, not elsewhere classified	0.000	0.993	0.007
R01.0 Benign and innocent cardiac murmurs	0.007	0.993	0.000
C30.1 Middle ear	0.000	0.993	0.007
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.993	0.007
C38.3 Mediastinum, part unspecified	0.000	0.993	0.007
Y44 Agents primarily affecting blood constituents	0.000	0.993	0.007
C34.9 Bronchus or lung, unspecified	0.000	0.993	0.007
C31.9 Accessory sinus, unspecified	0.000	0.993	0.006
C31.8 Overlapping lesion of accessory sinuses	0.000	0.993	0.006
C31.3 Sphenoidal sinus	0.000	0.993	0.006
C31.2 Frontal sinus	0.000	0.993	0.006
C31.1 Ethmoidal sinus	0.000	0.993	0.006
C31.0 Maxillary sinus	0.000	0.993	0.006
C39.9 Ill-defined sites within the respiratory system	0.000	0.993	0.006
C39.8 Overlapping lesion of respiratory and intrathoracic organs	0.000	0.993	0.006
C39.0 Upper respiratory tract, part unspecified	0.000	0.993	0.006
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.993	0.006
O63.0 Prolonged first stage (of labour)	0.000	0.994	0.006
R01 Cardiac murmurs and other cardiac sounds	0.006	0.994	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.994	0.005
F41.1 Generalised anxiety disorder	0.005	0.995	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.995	0.005
Y44.7 Plasma substitutes	0.000	0.995	0.005
Y44.6 Natural blood and blood products	0.000	0.995	0.005
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.995	0.005
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.995	0.005
I31.3 Pericardial effusion (noninflammatory)	0.005	0.995	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.000	0.995	0.005
R01.2 Other cardiac sounds	0.005	0.995	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.995	0.005
C34.0 Main bronchus	0.000	0.995	0.005
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.005	0.995	0.000
F30-F39 Mood [affective] disorders	0.005	0.995	0.000
D26.0 Cervix uteri	0.000	0.995	0.005
Y44.5 Thrombolytic drugs	0.000	0.995	0.004
I20.8 Other forms of angina pectoris	0.004	0.996	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.996	0.004
C22.9 Liver, unspecified	0.000	0.996	0.004
Chapter VIII Diseases of the ear and mastoid process	0.000	0.996	0.004
R15 Faecal incontinence	0.004	0.996	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.004	0.996	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.000	0.996	0.004
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
F38 Other mood [affective] disorders	0.004	0.996	0.000
F33 Recurrent depressive disorder	0.004	0.996	0.000
F34 Persistent mood [affective] disorders	0.003	0.996	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.997	0.003
M89.8 Other specified disorders of bone	0.000	0.997	0.003
R27 Other lack of coordination	0.000	0.997	0.003
F45.8 Other somatoform disorders	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.000	0.997	0.003
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.000	0.997	0.003
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.997	0.003
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.997	0.003
F33.4 Recurrent depressive disorder, currently in remission	0.003	0.997	0.000
G24.9 Dystonia, unspecified	0.003	0.997	0.000
F39 Unspecified mood [affective] disorder	0.003	0.997	0.000
F34.0 Cyclothymia	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
F38.0 Other single mood [affective] disorders	0.003	0.997	0.000
F38.8 Other specified mood [affective] disorders	0.003	0.997	0.000
F38.1 Other recurrent mood [affective] disorders	0.003	0.997	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.000	0.997	0.003
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.003	0.997	0.000
F33.8 Other recurrent depressive disorders	0.003	0.997	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.003	0.997	0.000
F34.8 Other persistent mood [affective] disorders	0.003	0.997	0.000
F30 Manic episode	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.000	0.997	0.003
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.997	0.003
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.997	0.003
B91 Sequelae of poliomyelitis	0.003	0.997	0.000
F45 Somatoform disorders	0.003	0.997	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.997	0.003
Q51.3 Bicornate uterus	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.997	0.002
F42.2 Mixed obsessional thoughts and acts	0.003	0.997	0.000
F42 Obsessive-compulsive disorder	0.003	0.997	0.000
F44.4 Dissociative motor disorders	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.997	0.003
F34.1 Dysthymia	0.002	0.997	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.997	0.000
K29.4 Chronic atrophic gastritis	0.000	0.997	0.003
R25 Abnormal involuntary movements	0.000	0.997	0.002
M89.84 Other specified disorders of bone (Hand)	0.000	0.997	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
F45.3 Somatoform autonomic dysfunction	0.002	0.998	0.000
F44 Dissociative [conversion] disorders	0.002	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
E05.9 Thyrotoxicosis, unspecified	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
G83.9 Paralytic syndrome, unspecified	0.000	0.998	0.002
F45.2 Hypochondriacal disorder	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
F41.8 Other specified anxiety disorders	0.002	0.998	0.000
F41 Other anxiety disorders	0.002	0.998	0.000
G83 Other paralytic syndromes	0.000	0.998	0.002
B02.9 Zoster without complication	0.002	0.998	0.000
C18.9 Colon, unspecified	0.000	0.998	0.002
F42.0 Predominantly obsessional thoughts or ruminations	0.002	0.998	0.000
G95.2 Cord compression, unspecified	0.000	0.998	0.002
F30.1 Mania without psychotic symptoms	0.002	0.998	0.000
F44.5 Dissociative convulsions	0.002	0.998	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.002	0.998	0.000
F30.8 Other manic episodes	0.002	0.998	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
F30.2 Mania with psychotic symptoms	0.002	0.998	0.000
F45.1 Undifferentiated somatoform disorder	0.002	0.998	0.000
F42.8 Other obsessive-compulsive disorders	0.002	0.998	0.000
G83.8 Other specified paralytic syndromes	0.000	0.998	0.002
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
M31.3 Wegener's granulomatosis	0.000	0.998	0.002
F42.1 Predominantly compulsive acts [obsessional rituals]	0.002	0.998	0.000
F45.4 Persistent somatoform pain disorder	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.998	0.002
R25.0 Abnormal head movements	0.000	0.998	0.002
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
E04.2 Non-toxic multinodular goitre	0.000	0.998	0.002
L92.0 Granuloma annulare	0.000	0.998	0.002
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C90.2 Plasmacytoma, extramedullary	0.002	0.998	0.000
T87.4 Infection of amputation stump	0.002	0.998	0.000
F44.8 Other dissociative [conversion] disorders	0.002	0.998	0.000
F44.7 Mixed dissociative [conversion] disorders	0.002	0.998	0.000
F44.6 Dissociative anaesthesia and sensory loss	0.002	0.998	0.000
F44.3 Trance and possession disorders	0.002	0.998	0.000
F44.2 Dissociative stupor	0.002	0.998	0.000
F44.1 Dissociative fugue	0.002	0.998	0.000
F45.9 Somatoform disorder, unspecified	0.002	0.998	0.000
D75.1 Secondary polycythaemia	0.002	0.998	0.000
F40.9 Phobic anxiety disorder, unspecified	0.002	0.998	0.000
F44.0 Dissociative amnesia	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
R32 Unspecified urinary incontinence	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
F40 Phobic anxiety disorders	0.002	0.998	0.000
G83.5 Locked-in syndrome	0.000	0.998	0.002
G83.3 Monoplegia, unspecified	0.000	0.998	0.002
G83.2 Monoplegia of upper limb	0.000	0.998	0.002
G83.0 Diplegia of upper limbs	0.000	0.998	0.002
M54.96 Dorsalgia, unspecified (Lumbar region)	0.002	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.998	0.001
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
F30.9 Manic episode, unspecified	0.002	0.998	0.000
F41.3 Other mixed anxiety disorders	0.002	0.998	0.000
F44.9 Dissociative [conversion] disorder, unspecified	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.002
F45.0 Somatisation disorder	0.002	0.998	0.000
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.002	0.998	0.000
D40.1 Testis	0.000	0.998	0.002
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.998	0.002
O63 Long labour	0.000	0.998	0.002
D75.8 Other specified diseases of blood and blood-forming organs	0.002	0.998	0.000
F30.0 Hypomania	0.001	0.998	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.998	0.002
O63.9 Long labour, unspecified	0.000	0.998	0.002
Z90.8 Acquired absence of other organs	0.000	0.998	0.002
G24 Dystonia	0.002	0.998	0.000
F40.1 Social phobias	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.998	0.002
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
T87.6 Other and unspecified complications of amputation stump	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
R25.2 Cramp and spasm	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
I74 Arterial embolism and thrombosis	0.000	0.998	0.002
F40.8 Other phobic anxiety disorders	0.001	0.998	0.000
G83.1 Monoplegia of lower limb	0.000	0.998	0.001
L81.9 Disorder of pigmentation, unspecified	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
S20.3 Other superficial injuries of front wall of thorax	0.000	0.998	0.002
T98.1 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
T98 Sequelae of other and unspecified effects of external causes	0.002	0.998	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.998	0.000
D51.2 Transcobalamin II deficiency	0.001	0.998	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.000	0.998	0.002
N71.1 Chronic inflammatory disease of uterus	0.002	0.998	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.002	0.998	0.000
N95 Menopausal and other perimenopausal disorders	0.000	0.998	0.002
O63.2 Delayed delivery of second twin, triplet, etc.	0.000	0.998	0.001
R25.3 Fasciculation	0.000	0.998	0.001
W19.9 Unspecified place	0.000	0.998	0.002
I31 Other diseases of pericardium	0.002	0.998	0.000
M89 Other disorders of bone	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.001	0.998	0.000
F40.2 Specific (isolated) phobias	0.002	0.998	0.000
G24.3 Spasmodic torticollis	0.001	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.000	0.998	0.001
M51.9 Intervertebral disk disorder, unspecified	0.002	0.998	0.000
B24 Unspecified human immunodeficiency virus [HIV] disease	0.002	0.998	0.000
F48 Other neurotic disorders	0.001	0.998	0.001
G24.1 Idiopathic familial dystonia	0.001	0.998	0.000
G82.5 Tetraplegia, unspecified	0.001	0.998	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.998	0.001
M34.1 CR(E)ST syndrome	0.001	0.998	0.000
W10.8 Other specified place	0.000	0.998	0.002
M34 Systemic sclerosis	0.002	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.001	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.001	0.998	0.000
O12.0 Gestational oedema	0.000	0.998	0.001
D26 Other benign neoplasms of uterus	0.000	0.998	0.001
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.998	0.000
S72.31 Fracture of shaft of femur (open)	0.001	0.999	0.000
C67.0 Trigone of bladder	0.001	0.999	0.000
F40.0 Agoraphobia	0.001	0.999	0.000
G24.5 Blepharospasm	0.001	0.999	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.999	0.001
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.001	0.999	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.001	0.999	0.000
S72.30 Fracture of shaft of femur (closed)	0.001	0.999	0.000
I31.0 Chronic adhesive pericarditis	0.001	0.999	0.000
T91.1 Sequelae of fracture of spine	0.001	0.999	0.000
Y04.5 Trade and service area	0.001	0.999	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.001	0.999	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.999	0.001
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.999	0.001
M25.77 Osteophyte (Ankle and foot)	0.001	0.999	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.999	0.001
S72.11 Pertrochanteric fracture (open)	0.001	0.999	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.999	0.001
H43.9 Disorder of vitreous body, unspecified	0.000	0.999	0.001
M34.0 Progressive systemic sclerosis	0.001	0.999	0.000
T98.2 Sequelae of certain early complications of trauma	0.001	0.999	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.999	0.001
Z13.1 Special screening examination for diabetes mellitus	0.001	0.999	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.999	0.001
M89.6 Osteopathy after poliomyelitis	0.000	0.999	0.001
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.999	0.001
M89.2 Other disorders of bone development and growth	0.000	0.999	0.001
M89.1 Epiphyseal arrest	0.000	0.999	0.001
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.000	0.999	0.001
M89.98 Disorder of bone, unspecified (Other)	0.000	0.999	0.001
F48.8 Other specified neurotic disorders	0.001	0.999	0.001
F48.1 Depersonalisation-derealisation syndrome	0.001	0.999	0.001
G24.0 Drug-induced dystonia	0.001	0.999	0.000
I31.8 Other specified diseases of pericardium	0.001	0.999	0.000
I31.2 Haemopericardium, not elsewhere classified	0.001	0.999	0.000
I31.1 Chronic constrictive pericarditis	0.001	0.999	0.000
R07.0 Pain in throat	0.000	0.999	0.001
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.001	0.999	0.000
T91 Sequelae of injuries of neck and trunk	0.001	0.999	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.001	0.999	0.000
B02.2 Zoster with other nervous system involvement	0.001	0.999	0.000
D26.7 Other parts of uterus	0.000	0.999	0.001
F48.9 Neurotic disorder, unspecified	0.001	0.999	0.001
M34.2 Systemic sclerosis induced by drugs and chemicals	0.001	0.999	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.999	0.001
Q51.4 Unicornate uterus	0.001	0.999	0.000
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.001	0.999	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.000	0.999	0.001
I38 Endocarditis, valve unspecified	0.001	0.999	0.000
S02.60 Fracture of mandible (closed)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.000	0.999	0.001
G82.1 Spastic paraplegia	0.001	0.999	0.000
M89.9 Disorder of bone, unspecified	0.000	0.999	0.001
T94 Sequelae of injuries involving multiple and unspecified body regions	0.001	0.999	0.000
Z50 Care involving use of rehabilitation procedures	0.000	0.999	0.001
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.999	0.000
M21.3 Wrist or foot drop (acquired)	0.000	0.999	0.001
M89.3 Hypertrophy of bone	0.000	0.999	0.001
N95.9 Menopausal and perimenopausal disorder, unspecified	0.000	0.999	0.001
Z90.6 Acquired absence of other parts of urinary tract	0.000	0.999	0.001
Q27 Other congenital malformations of peripheral vascular system	0.001	0.999	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.999	0.001
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.999	0.001
D33.3 Cranial nerves	0.001	0.999	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.999	0.001
M87.2 Osteonecrosis due to previous trauma	0.000	0.999	0.001
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.999	0.001
Z22.5 Carrier of viral hepatitis	0.000	0.999	0.001
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.999	0.001
M89.18 Epiphyseal arrest (Other)	0.000	0.999	0.001
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.999	0.001
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.999	0.001
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.999	0.001
M89.14 Epiphyseal arrest (Hand)	0.000	0.999	0.001
M89.13 Epiphyseal arrest (Forearm)	0.000	0.999	0.001
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.999	0.001
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.999	0.001
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.999	0.001
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.999	0.001
M89.28 Other disorders of bone development and growth (Other)	0.000	0.999	0.001
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.999	0.001
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.999	0.001
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.999	0.001
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.999	0.001
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.999	0.001
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.999	0.001
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.999	0.001
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.999	0.001
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.999	0.001
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.999	0.001
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.999	0.001
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.999	0.001
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.999	0.001
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.999	0.001
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.999	0.001
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.999	0.001
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.999	0.001
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.999	0.001
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.999	0.001
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.999	0.001
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.999	0.001
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.999	0.001
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.999	0.001
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.999	0.001
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.999	0.001
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.999	0.001
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.999	0.001
D26.1 Corpus uteri	0.000	0.999	0.001
G82.2 Paraplegia, unspecified	0.001	0.999	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.000	0.999	0.001
H95.8 Other postprocedural disorders of ear and mastoid process	0.000	0.999	0.001
I86.1 Scrotal varices	0.001	0.999	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.001	0.999	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.001	0.999	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.001	0.999	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.001	0.999	0.000
B02 Zoster [herpes zoster]	0.001	0.999	0.000
Q51 Congenital malformations of uterus and cervix	0.001	0.999	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
M89.38 Hypertrophy of bone (Other)	0.000	0.999	0.001
C22.7 Other specified carcinomas of liver	0.000	0.999	0.001
C22.4 Other sarcomas of liver	0.000	0.999	0.001
C22.3 Angiosarcoma of liver	0.000	0.999	0.001
C22.2 Hepatoblastoma	0.000	0.999	0.001
M89.5 Osteolysis	0.000	0.999	0.001
T92.0 Sequelae of open wound of upper limb	0.000	0.999	0.001
M24.14 Other articular cartilage disorders (Hand)	0.001	0.999	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.999	0.001
F48.0 Neurasthenia	0.001	0.999	0.001
N95.1 Menopausal and female climacteric states	0.000	0.999	0.001
T91.3 Sequelae of injury of spinal cord	0.001	0.999	0.000
T87 Complications peculiar to reattachment and amputation	0.001	0.999	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.999	0.001
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.999	0.001
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.999	0.001
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.999	0.001
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.999	0.001
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.999	0.001
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.999	0.001
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.999	0.001
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.999	0.001
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.999	0.001
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.999	0.001
M89.34 Hypertrophy of bone (Hand)	0.000	0.999	0.001
M89.33 Hypertrophy of bone (Forearm)	0.000	0.999	0.001
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.999	0.001
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.999	0.001
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.999	0.001
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.999	0.001
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.999	0.001
L50.9 Urticaria, unspecified	0.001	0.999	0.000
M89.0 Algoneurodystrophy	0.000	0.999	0.001
Q27.4 Congenital phlebectasia	0.001	0.999	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.999	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.999	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.999	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.999	0.001
Z50.6 Orthoptic training	0.000	0.999	0.001
B18 Chronic viral hepatitis	0.000	0.999	0.001
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.999	0.001
B18.9 Chronic viral hepatitis, unspecified	0.000	0.999	0.001
M24.1 Other articular cartilage disorders	0.001	0.999	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.999	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.999	0.001
Z50.5 Speech therapy	0.000	0.999	0.001
G82 Paraplegia and tetraplegia	0.001	0.999	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.999	0.001
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.999	0.001
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.999	0.001
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.999	0.001
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.999	0.001
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.999	0.001
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.999	0.001
N81.3 Complete uterovaginal prolapse	0.000	0.999	0.001
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.001	0.999	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.001	0.999	0.000
Q51.6 Embryonic cyst of cervix	0.001	0.999	0.000
Q51.5 Agenesis and aplasia of cervix	0.001	0.999	0.000
Q51.0 Agenesis and aplasia of uterus	0.001	0.999	0.000
M24.26 Disorder of ligament (Lower leg)	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.999	0.001
M89.59 Osteolysis (Site unspecified)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations