TreeWAS – Variant ID: rs2041840

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.121	0.879
Z35.5 Supervision of elderly primigravida	0.000	0.844	0.156
Z35 Supervision of high-risk pregnancy	0.000	0.845	0.155
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.857	0.143
Z35.8 Supervision of other high-risk pregnancies	0.000	0.860	0.140
Z35.1 Supervision of pregnancy with history of abortive outcome	0.000	0.860	0.140
Z35.4 Supervision of pregnancy with grand multiparity	0.000	0.864	0.136
I10-I15 Hypertensive diseases	0.000	0.879	0.121
Z35.7 Supervision of high-risk pregnancy due to social problems	0.000	0.889	0.111
Z35.6 Supervision of very young primigravida	0.000	0.889	0.111
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.000	0.889	0.111
Z35.9 Supervision of high-risk pregnancy, unspecified	0.000	0.889	0.111
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.000	0.901	0.099
Z37.0 Single live birth	0.000	0.902	0.098
Z36 Antenatal screening	0.000	0.902	0.098
Z36.0 Antenatal screening for chromosomal anomalies	0.000	0.902	0.098
Z37 Outcome of delivery	0.000	0.903	0.097
I13 Hypertensive heart and renal disease	0.000	0.907	0.093
Z36.8 Other antenatal screening	0.000	0.908	0.092
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.908	0.092
Z32 Pregnancy examination and test	0.000	0.919	0.081
Z37.1 Single stillbirth	0.000	0.920	0.080
Z37.5 Other multiple births, all liveborn	0.000	0.925	0.075
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.926	0.074
Z36.5 Antenatal screening for isoimmunisation	0.000	0.929	0.070
Z37.9 Outcome of delivery unspecified	0.000	0.930	0.070
Z37.7 Other multiple births, all stillborn	0.000	0.930	0.070
Z37.6 Other multiple births, some liveborn	0.000	0.930	0.070
Z37.4 Twins, both stillborn	0.000	0.930	0.070
Z37.3 Twins, one liveborn and one stillborn	0.000	0.930	0.070
I11 Hypertensive heart disease	0.000	0.931	0.069
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.931	0.069
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.932	0.068
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.933	0.067
Z31 Procreative management	0.000	0.934	0.066
I12 Hypertensive renal disease	0.000	0.934	0.066
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.935	0.065
Z38 Liveborn infants according to place of birth	0.000	0.936	0.064
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.000	0.941	0.058
Z32.1 Pregnancy confirmed	0.000	0.942	0.058
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.943	0.057
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.000	0.946	0.054
Z31.4 Procreative investigation and testing	0.000	0.947	0.053
Z31.9 Procreative management, unspecified	0.000	0.947	0.053
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.947	0.052
I12.9 Hypertensive renal disease without renal failure	0.000	0.948	0.052
Z31.8 Other procreative management	0.000	0.949	0.051
Z31.6 General counselling and advice on procreation	0.000	0.949	0.051
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.000	0.952	0.048
Z31.5 Genetic counselling	0.000	0.953	0.047
Z31.1 Artifical insemination	0.000	0.953	0.047
Z39 Postpartum care and examination	0.000	0.953	0.047
Z38.8 Other multiple, unspecified as to place of birth	0.000	0.954	0.046
Z38.7 Other multiple, born outside hospital	0.000	0.954	0.046
Z38.6 Other multiple, born in hospital	0.000	0.954	0.046
Z38.5 Twin, unspecified as to place of birth	0.000	0.954	0.046
Z38.4 Twin, born outside hospital	0.000	0.954	0.046
Z38.3 Twin, born in hospital	0.000	0.954	0.046
Z38.2 Singleton, unspecified as to place of birth	0.000	0.954	0.046
Z38.1 Singleton, born outside hospital	0.000	0.954	0.046
I15 Secondary hypertension	0.001	0.956	0.043
Z38.0 Singleton, born in hospital	0.000	0.961	0.039
Z31.3 Other assisted fertilisation methods	0.000	0.962	0.038
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.000	0.963	0.037
Z36.2 Other antenatal screening based on amniocentesis	0.001	0.965	0.034
K70.9 Alcoholic liver disease, unspecified	0.034	0.966	0.000
Z31.2 In vitro fertilisation	0.000	0.966	0.034
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.966	0.034
Z39.1 Care and examination of lactating mother	0.000	0.967	0.033
K70 Alcoholic liver disease	0.032	0.968	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.968	0.031
Z36.9 Antenatal screening, unspecified	0.000	0.969	0.031
K70.3 Alcoholic cirrhosis of liver	0.029	0.971	0.000
I15.0 Renovascular hypertension	0.001	0.971	0.028
I15.2 Hypertension secondary to endocrine disorders	0.001	0.972	0.028
I15.8 Other secondary hypertension	0.001	0.972	0.028
K70.4 Alcoholic hepatic failure	0.028	0.972	0.000
Z39.0 Care and examination immediately after delivery	0.000	0.973	0.027
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.973	0.026
K70.0 Alcoholic fatty liver	0.025	0.975	0.000
Z37.2 Twins, both liveborn	0.000	0.975	0.025
K70.2 Alcoholic fibrosis and sclerosis of liver	0.024	0.976	0.000
Z39.2 Routine postpartum follow-up	0.000	0.976	0.023
Z33 Pregnant state, incidental	0.000	0.979	0.021
D69.6 Thrombocytopenia, unspecified	0.020	0.980	0.000
Z34 Supervision of normal pregnancy	0.000	0.980	0.020
K70-K77 Diseases of liver	0.018	0.982	0.000
K74 Fibrosis and cirrhosis of liver	0.017	0.983	0.000
K72 Hepatic failure, not elsewhere classified	0.017	0.983	0.000
K70.1 Alcoholic hepatitis	0.017	0.983	0.000
K74.3 Primary biliary cirrhosis	0.017	0.983	0.000
Z30 Contraceptive management	0.000	0.983	0.017
K72.9 Hepatic failure, unspecified	0.017	0.983	0.000
K74.6 Other and unspecified cirrhosis of liver	0.016	0.984	0.000
I15.1 Hypertension secondary to other renal disorders	0.001	0.985	0.014
Z80.4 Family history of malignant neoplasm of genital organs	0.014	0.986	0.000
K77 Liver disorders in diseases classified elsewhere	0.014	0.986	0.000
K72.0 Acute and subacute hepatic failure	0.014	0.986	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.987	0.013
I12.0 Hypertensive renal disease with renal failure	0.000	0.987	0.013
K74.4 Secondary biliary cirrhosis	0.013	0.987	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.013	0.987	0.000
Z30.9 Contraceptive management, unspecified	0.000	0.987	0.012
I20.8 Other forms of angina pectoris	0.000	0.988	0.012
K75 Other inflammatory liver diseases	0.012	0.988	0.000
Z30.8 Other contraceptive management	0.000	0.988	0.012
K72.1 Chronic hepatic failure	0.012	0.988	0.000
Z30.1 Insertion of (intra-uterine) contraceptive device	0.000	0.988	0.012
K71 Toxic liver disease	0.012	0.988	0.000
Z30.3 Menstrual extraction	0.000	0.988	0.012
Z30.0 General counselling and advice on contraception	0.000	0.988	0.011
K74.1 Hepatic sclerosis	0.011	0.989	0.000
K74.5 Biliary cirrhosis, unspecified	0.011	0.989	0.000
Z30.4 Surveillance of contraceptive drugs	0.000	0.989	0.011
C71.9 Brain, unspecified	0.000	0.989	0.011
K77.8 Liver disorders in other diseases classified elsewhere	0.010	0.989	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.010	0.990	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
K73 Chronic hepatitis, not elsewhere classified	0.010	0.990	0.000
K75.4 Autoimmune hepatitis	0.010	0.990	0.000
K75.8 Other specified inflammatory liver diseases	0.010	0.990	0.000
K71.9 Toxic liver disease, unspecified	0.009	0.991	0.000
S62.50 Fracture of thumb (closed)	0.000	0.991	0.009
K75.2 Nonspecific reactive hepatitis	0.009	0.991	0.000
K75.1 Phlebitis of portal vein	0.009	0.991	0.000
K71.8 Toxic liver disease with other disorders of liver	0.009	0.991	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.009	0.991	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.009	0.991	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.009	0.991	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.009	0.991	0.000
K71.2 Toxic liver disease with acute hepatitis	0.009	0.991	0.000
C18.2 Ascending colon	0.008	0.992	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.008	0.992	0.000
K71.0 Toxic liver disease with cholestasis	0.008	0.992	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.992	0.008
K74.0 Hepatic fibrosis	0.008	0.992	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.008	0.992	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.992	0.008
K71.1 Toxic liver disease with hepatic necrosis	0.008	0.992	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.008	0.992	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.007	0.992	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.007	0.992	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.007	0.993	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.000	0.993	0.007
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.993	0.007
R93 Abnormal findings on diagnostic imaging of other body structures	0.007	0.993	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.993	0.007
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.007	0.993	0.000
S62.5 Fracture of thumb	0.000	0.993	0.007
K73.2 Chronic active hepatitis, not elsewhere classified	0.006	0.993	0.000
C71.2 Temporal lobe	0.000	0.994	0.006
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.994	0.006
K76 Other diseases of liver	0.006	0.994	0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.006	0.994	0.000
K75.0 Abscess of liver	0.006	0.994	0.000
K75.9 Inflammatory liver disease, unspecified	0.006	0.994	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.006	0.994	0.000
K76.6 Portal hypertension	0.006	0.994	0.000
C71 Malignant neoplasm of brain	0.000	0.994	0.006
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.994	0.006
F31.9 Bipolar affective disorder, unspecified	0.000	0.994	0.006
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.006	0.994	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.994	0.005
C78.2 Secondary malignant neoplasm of pleura	0.006	0.994	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.995	0.005
C71.8 Overlapping lesion of brain	0.000	0.995	0.005
S62.51 Fracture of thumb (open)	0.000	0.995	0.005
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.995	0.005
K73.9 Chronic hepatitis, unspecified	0.005	0.995	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.995	0.005
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.995	0.005
K76.3 Infarction of liver	0.005	0.995	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.995	0.005
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.995	0.005
T82.1 Mechanical complication of cardiac electronic device	0.000	0.995	0.005
K76.5 Hepatic veno-occlusive disease	0.005	0.995	0.000
K76.4 Peliosis hepatis	0.005	0.995	0.000
K76.2 Central haemorrhagic necrosis of liver	0.005	0.995	0.000
S62 Fracture at wrist and hand level	0.000	0.995	0.005
F31 Bipolar affective disorder	0.000	0.995	0.005
K76.8 Other specified diseases of liver	0.005	0.995	0.000
K76.7 Hepatorenal syndrome	0.004	0.995	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.996	0.004
C71.5 Cerebral ventricle	0.000	0.996	0.004
C71.6 Cerebellum	0.000	0.996	0.004
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.996	0.004
R49.0 Dysphonia	0.000	0.996	0.004
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.004	0.996	0.000
K76.1 Chronic passive congestion of liver	0.004	0.996	0.000
C71.7 Brain stem	0.000	0.996	0.004
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.004	0.996	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.996	0.004
T82.3 Mechanical complication of other vascular grafts	0.000	0.996	0.004
F31.7 Bipolar affective disorder, currently in remission	0.000	0.996	0.004
I86.1 Scrotal varices	0.004	0.996	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.996	0.004
S69.7 Multiple injuries of wrist and hand	0.000	0.996	0.004
S67 Crushing injury of wrist and hand	0.000	0.996	0.004
S69 Other and unspecified injuries of wrist and hand	0.000	0.996	0.004
S62.31 Fracture of other metacarpal bone (open)	0.000	0.996	0.003
C71.4 Occipital lobe	0.000	0.996	0.003
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.996	0.004
S62.4 Multiple fractures of metacarpal bones	0.000	0.996	0.003
C71.0 Cerebrum, except lobes and ventricles	0.000	0.997	0.003
C73 Malignant neoplasm of thyroid gland	0.000	0.997	0.003
S60-S69 Injuries to the wrist and hand	0.000	0.997	0.003
C71.3 Parietal lobe	0.000	0.997	0.003
S64.3 Injury of digital nerve of thumb	0.000	0.997	0.003
D69 Purpura and other haemorrhagic conditions	0.003	0.997	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.997	0.003
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.997	0.003
S62.2 Fracture of first metacarpal bone	0.000	0.997	0.003
S62.1 Fracture of other carpal bone(s)	0.000	0.997	0.003
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
N60.8 Other benign mammary dysplasias	0.000	0.997	0.003
F31.8 Other bipolar affective disorders	0.000	0.997	0.003
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.997	0.003
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.997	0.003
S64 Injury of nerves at wrist and hand level	0.000	0.997	0.003
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.997	0.003
D69.2 Other nonthrombocytopenic purpura	0.003	0.997	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.997	0.003
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.997	0.003
Y84.8 Other medical procedures	0.003	0.997	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.003
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.000	0.997	0.003
S69.9 Unspecified injury of wrist and hand	0.000	0.997	0.003
S68 Traumatic amputation of wrist and hand	0.000	0.997	0.003
D69.4 Other primary thrombocytopenia	0.003	0.997	0.000
K12.2 Cellulitis and abscess of mouth	0.003	0.997	0.000
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.997	0.003
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.997	0.003
K08.9 Disorder of teeth and supporting structures, unspecified	0.003	0.997	0.000
S69.8 Other specified injuries of wrist and hand	0.000	0.997	0.003
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.997	0.003
S82.31 Fracture of lower end of tibia (open)	0.000	0.997	0.003
N60.2 Fibroadenosis of breast	0.000	0.997	0.003
S62.7 Multiple fractures of fingers	0.000	0.997	0.003
S65 Injury of blood vessels at wrist and hand level	0.000	0.997	0.003
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.997	0.003
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.997	0.003
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.003	0.997	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.997	0.003
J03.9 Acute tonsillitis, unspecified	0.000	0.997	0.003
S22.0 Fracture of thoracic vertebra	0.000	0.997	0.003
S62.21 Fracture of first metacarpal bone (open)	0.000	0.997	0.002
D69.8 Other specified haemorrhagic conditions	0.002	0.997	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.997	0.002
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.997	0.003
N80.2 Endometriosis of Fallopian tube	0.000	0.997	0.003
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.997	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.997	0.002
S64.8 Injury of other nerves at wrist and hand level	0.000	0.997	0.002
S64.1 Injury of median nerve at wrist and hand level	0.000	0.997	0.002
G70.0 Myasthenia gravis	0.003	0.997	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.997	0.002
D69.9 Haemorrhagic condition, unspecified	0.002	0.998	0.000
J98.4 Other disorders of lung	0.000	0.998	0.002
R41.3 Other amnesia	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.998	0.002
R49 Voice disturbances	0.000	0.998	0.002
J04.1 Acute tracheitis	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z34.8 Supervision of other normal pregnancy	0.000	0.998	0.002
C74.9 Adrenal gland, unspecified	0.000	0.998	0.002
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.998	0.002
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.998	0.002
S68.4 Traumatic amputation of hand at wrist level	0.000	0.998	0.002
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.998	0.002
C71.1 Frontal lobe	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.002	0.998	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.998	0.002
D69.1 Qualitative platelet defects	0.002	0.998	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.998	0.002
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.998	0.002
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.998	0.002
S65.3 Injury of deep palmar arch	0.000	0.998	0.002
S65.2 Injury of superficial palmar arch	0.000	0.998	0.002
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.998	0.002
T42.4 Benzodiazepines	0.000	0.998	0.002
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.998	0.002
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.998	0.002
S65.5 Injury of blood vessel(s) of other finger	0.000	0.998	0.002
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.002	0.998	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
R49.1 Aphonia	0.000	0.998	0.002
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
C74 Malignant neoplasm of adrenal gland	0.000	0.998	0.002
S22.01 Fracture of thoracic vertebra (open)	0.000	0.998	0.002
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.998	0.002
D69.0 Allergic purpura	0.002	0.998	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.998	0.002
J03 Acute tonsillitis	0.000	0.998	0.002
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.998	0.002
S65.4 Injury of blood vessel(s) of thumb	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
D07.1 Vulva	0.000	0.998	0.002
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.998	0.002
S81.0 Open wound of knee	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.002
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.998	0.002
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
R49.2 Hypernasality and hyponasality	0.000	0.998	0.002
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
O16 Unspecified maternal hypertension	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.002
S42.10 Fracture of scapula (closed)	0.002	0.998	0.000
C75.0 Parathyroid gland	0.000	0.998	0.002
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.002	0.998	0.000
R23.4 Changes in skin texture	0.000	0.998	0.002
R49.8 Other and unspecified voice disturbances	0.000	0.998	0.002
R76.8 Other specified abnormal immunological findings in serum	0.002	0.998	0.000
C75.9 Endocrine gland, unspecified	0.000	0.998	0.002
H05.0 Acute inflammation of orbit	0.002	0.998	0.000
C75.1 Pituitary gland	0.000	0.998	0.002
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.998	0.002
J04 Acute laryngitis and tracheitis	0.000	0.998	0.002
C75.5 Aortic body and other paraganglia	0.000	0.998	0.002
S63.2 Multiple dislocations of fingers	0.000	0.998	0.002
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
C75.8 Pluriglandular involvement, unspecified	0.000	0.998	0.002
C75.4 Carotid body	0.000	0.998	0.002
C75.3 Pineal gland	0.000	0.998	0.002
C75.2 Craniopharyngeal duct	0.000	0.998	0.002
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.998	0.002
J03.0 Streptococcal tonsillitis	0.000	0.998	0.002
S62.6 Fracture of other finger	0.000	0.998	0.002
S63.1 Dislocation finger	0.000	0.998	0.002
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.998	0.002
S65.1 Injury of radial artery at wrist and hand level	0.000	0.998	0.002
Z87.1 Personal history of diseases of the digestive system	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.002	0.998	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
C74.0 Cortex of adrenal gland	0.000	0.998	0.002
K12.0 Recurrent oral aphthae	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.998	0.002
S41.1 Open wound of upper arm	0.002	0.998	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.998	0.002
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.000	0.998	0.002
R10.1 Pain localised to upper abdomen	0.002	0.998	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.002	0.998	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.002	0.998	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.002	0.998	0.000
R41.2 Retrograde amnesia	0.002	0.998	0.000
J00-J06 Acute upper respiratory infections	0.000	0.998	0.002
C18.1 Appendix	0.002	0.998	0.000
W25.9 Unspecified place	0.000	0.998	0.002
C74.1 Medulla of adrenal gland	0.000	0.998	0.001
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
O04.9 Complete or unspecified, without complication	0.000	0.998	0.002
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
K12 Stomatitis and related lesions	0.002	0.998	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
K12.1 Other forms of stomatitis	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.000	0.998	0.002
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
W07.0 Home	0.000	0.998	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
C18 Malignant neoplasm of colon	0.002	0.998	0.000
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
J04.2 Acute laryngotracheitis	0.000	0.998	0.001
K56.6 Other and unspecified intestinal obstruction	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.000	0.998	0.002
S63.6 Sprain and strain of finger(s)	0.000	0.998	0.002
Z71.2 Person consulting for explanation of investigation findings	0.000	0.998	0.002
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.000	0.998	0.001
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.002	0.998	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.001
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.998	0.001
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.998	0.002
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
C70 Malignant neoplasm of meninges	0.000	0.998	0.001
S61 Open wound of wrist and hand	0.000	0.998	0.002
K76.9 Liver disease, unspecified	0.001	0.998	0.000
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
Z58.1 Exposure to air pollution	0.000	0.998	0.001
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.001	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.001	0.999	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.001	0.999	0.001
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.001	0.999	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.999	0.001
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.999	0.001
M62.82 Other specified disorders of muscle (Upper arm)	0.001	0.999	0.000
D07.5 Prostate	0.000	0.999	0.001
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
N04.9 Unspecified	0.000	0.999	0.001
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.001	0.999	0.000
S63.0 Dislocation of wrist	0.000	0.999	0.001
C72.0 Spinal cord	0.000	0.999	0.001
J05.1 Acute epiglottitis	0.000	0.999	0.001
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.999	0.001
R92 Abnormal findings on diagnostic imaging of breast	0.001	0.999	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
G11.1 Early-onset cerebellar ataxia	0.001	0.999	0.000
H93.1 Tinnitus	0.000	0.999	0.001
R41.1 Anterograde amnesia	0.001	0.999	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
S63.5 Sprain and strain of wrist	0.000	0.999	0.001
R41 Other symptoms and signs involving cognitive functions and awareness	0.001	0.999	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.999	0.001
Z58.8 Other problems related to physical environment	0.000	0.999	0.001
C72.9 Central nervous system, unspecified	0.000	0.999	0.001
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.999	0.001
C72.5 Other and unspecified cranial nerves	0.000	0.999	0.001
C72.4 Acoustic nerve	0.000	0.999	0.001
C72.3 Optic nerve	0.000	0.999	0.001
C72.2 Olfactory nerve	0.000	0.999	0.001
C72.1 Cauda equina	0.000	0.999	0.001
J05.0 Acute obstructive laryngitis [croup]	0.000	0.999	0.001
S42.1 Fracture of scapula	0.001	0.999	0.000
S82.3 Fracture of lower end of tibia	0.000	0.999	0.001
M62 Other disorders of muscle	0.001	0.999	0.000
S42.30 Fracture of shaft of humerus (closed)	0.001	0.999	0.000
L23.1 Allergic contact dermatitis due to adhesives	0.001	0.999	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.999	0.001
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
C70.9 Meninges, unspecified	0.000	0.999	0.001
C70.1 Spinal meninges	0.000	0.999	0.001
R47.1 Dysarthria and anarthria	0.001	0.999	0.000
S22.5 Flail chest	0.000	0.999	0.001
C70.0 Cerebral meninges	0.000	0.999	0.001
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.999	0.001
D07 Carcinoma in situ of other and unspecified genital organs	0.000	0.999	0.001
G11 Hereditary ataxia	0.001	0.999	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.999	0.001
W19.2 School, other institution and public administrative area	0.001	0.999	0.000
S42.31 Fracture of shaft of humerus (open)	0.001	0.999	0.000
J17.3 Pneumonia in parasitic diseases	0.000	0.999	0.001
M62.4 Contracture of muscle	0.001	0.999	0.000
S61.0 Open wound of finger(s) without damage to nail	0.000	0.999	0.001
M62.83 Other specified disorders of muscle (Forearm)	0.001	0.999	0.000
G11.4 Hereditary spastic paraplegia	0.001	0.999	0.000
M62.6 Muscle strain	0.001	0.999	0.000
O63.0 Prolonged first stage (of labour)	0.001	0.999	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.999	0.000
S42.11 Fracture of scapula (open)	0.001	0.999	0.000
C18.0 Caecum	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.000	0.999	0.001
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
S22.51 Flail chest (open)	0.000	0.999	0.001
D07.2 Vagina	0.000	0.999	0.001
I77.6 Arteritis, unspecified	0.000	0.999	0.001
M15.2 Bouchard's nodes (with arthropathy)	0.001	0.999	0.000
Z58.5 Exposure to other pollution	0.000	0.999	0.001
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.001	0.999	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.999	0.001
D07.6 Other and unspecified male genital organs	0.000	0.999	0.001
D07.3 Other and unspecified female genital organs	0.000	0.999	0.001
D07.0 Endometrium	0.000	0.999	0.001
D26.1 Corpus uteri	0.001	0.999	0.000
G11.8 Other hereditary ataxias	0.001	0.999	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.001	0.999	0.000
G11.2 Late-onset cerebellar ataxia	0.001	0.999	0.000
G11.0 Congenital nonprogressive ataxia	0.001	0.999	0.000
I85.0 Oesophageal varices with bleeding	0.001	0.999	0.000
L60.8 Other nail disorders	0.000	0.999	0.001
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
M62.0 Diastasis of muscle	0.001	0.999	0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.000	0.999	0.001
S02.6 Fracture of mandible	0.001	0.999	0.000
S42.3 Fracture of shaft of humerus	0.001	0.999	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.999	0.001
G70 Myasthenia gravis and other myoneural disorders	0.001	0.999	0.000
M62.46 Contracture of muscle (Lower leg)	0.001	0.999	0.000
C18.6 Descending colon	0.001	0.999	0.000
D07.4 Penis	0.000	0.999	0.001
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.999	0.001
J01 Acute sinusitis	0.000	0.999	0.001
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.001	0.999	0.000
M62.49 Contracture of muscle (Site unspecified)	0.001	0.999	0.000
M62.48 Contracture of muscle (Other)	0.001	0.999	0.000
M62.47 Contracture of muscle (Ankle and foot)	0.001	0.999	0.000
M62.45 Contracture of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.44 Contracture of muscle (Hand)	0.001	0.999	0.000
M62.43 Contracture of muscle (Forearm)	0.001	0.999	0.000
M62.42 Contracture of muscle (Upper arm)	0.001	0.999	0.000
M62.41 Contracture of muscle (Shoulder region)	0.001	0.999	0.000
M62.40 Contracture of muscle (Multiple sites)	0.001	0.999	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.000	0.999	0.001
C18.7 Sigmoid colon	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations