TreeWAS – Variant ID: rs2047937

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.495	0.505	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.489	0.511	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.487	0.513	0.000
T39.0 Salicylates	0.477	0.523	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.474	0.526	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.469	0.531	0.000
T43.2 Other and unspecified antidepressants	0.462	0.538	0.000
T39.1 4-Aminophenol derivatives	0.452	0.548	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.444	0.556	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.440	0.560	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.429	0.571	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.429	0.571	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.420	0.580	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.398	0.602	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.394	0.606	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.387	0.613	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.381	0.619	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.379	0.621	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.369	0.631	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.368	0.632	0.000
T38.0 Glucocorticoids and synthetic analogues	0.359	0.641	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.357	0.643	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.357	0.643	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.356	0.644	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.355	0.645	0.000
T39.4 Antirheumatics, not elsewhere classified	0.351	0.649	0.000
T39.2 Pyrazolone derivatives	0.351	0.649	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.349	0.651	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.349	0.651	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.349	0.651	0.000
T46.7 Peripheral vasodilators	0.349	0.651	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.348	0.652	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.344	0.656	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.342	0.658	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.340	0.660	0.000
T38.1 Thyroid hormones and substitutes	0.335	0.665	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.335	0.665	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.334	0.666	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.333	0.667	0.000
T36 Poisoning by systemic antibiotics	0.328	0.671	0.000
T38.5 Other oestrogens and progestogens	0.326	0.674	0.000
T43.6 Psychostimulants with abuse potential	0.326	0.674	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.323	0.677	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.322	0.678	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.321	0.678	0.000
T38.9 Other and unspecified hormone antagonists	0.318	0.682	0.000
T38.7 Androgens and anabolic congeners	0.318	0.682	0.000
T38.4 Oral contraceptives	0.318	0.682	0.000
T38.2 Antithyroid drugs	0.318	0.682	0.000
T43.9 Psychotropic drug, unspecified	0.318	0.682	0.000
T50.8 Diagnostic agents	0.318	0.682	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.315	0.684	0.000
T37.5 Antiviral drugs	0.315	0.684	0.000
T37.4 Anthelminthics	0.315	0.684	0.000
T37.3 Other antiprotozoal drugs	0.315	0.684	0.000
T37.1 Antimycobacterial drugs	0.315	0.684	0.000
T37.0 Sulphonamides	0.315	0.684	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.307	0.692	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.307	0.692	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.307	0.692	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.307	0.692	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.307	0.692	0.000
T44.0 Anticholinesterase agents	0.307	0.692	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.305	0.695	0.000
T46.1 Calcium-channel blockers	0.291	0.709	0.000
T50.4 Drugs affecting uric acid metabolism	0.287	0.713	0.000
T40.2 Other opioids	0.283	0.717	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.281	0.719	0.000
T50.7 Analeptics and opioid receptor antagonists	0.278	0.722	0.000
T50.5 Appetite depressants	0.278	0.722	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.278	0.722	0.000
T50.0 Mineralocorticoids and their antagonists	0.278	0.722	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.277	0.722	0.000
T50.1 Loop [high-ceiling] diuretics	0.273	0.727	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.272	0.728	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.267	0.733	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.266	0.734	0.000
T40.3 Methadone	0.264	0.736	0.000
T40.1 Heroin	0.263	0.737	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.259	0.741	0.000
T49.9 Topical agent, unspecified	0.256	0.744	0.000
T49.8 Other topical agents	0.256	0.744	0.000
T49.7 Dental drugs, topically applied	0.256	0.744	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.256	0.744	0.000
T49.5 Ophthalmological drugs and preparations	0.256	0.744	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.256	0.744	0.000
T49.3 Emollients, demulcents and protectants	0.256	0.744	0.000
T49.2 Local astringents and local detergents	0.256	0.744	0.000
T49.1 Antipruritics	0.256	0.744	0.000
T41.5 Therapeutic gases	0.254	0.745	0.000
T41.4 Anaesthetic, unspecified	0.254	0.745	0.000
T41.3 Local anaesthetics	0.254	0.745	0.000
T41.2 Other and unspecified general anaesthetics	0.254	0.745	0.000
T41.1 Intravenous anaesthetics	0.254	0.745	0.000
T41.0 Inhaled anaesthetics	0.254	0.745	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.252	0.748	0.000
T47.0 Histamine H(2)-receptor antagonists	0.251	0.748	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.251	0.748	0.000
T40.5 Cocaine	0.251	0.749	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.251	0.749	0.000
T48.4 Expectorants	0.251	0.749	0.000
T48.3 Antitussives	0.251	0.749	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.251	0.749	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.251	0.749	0.000
T48.0 Oxytocic drugs	0.251	0.749	0.000
T36.8 Other systemic antibiotics	0.250	0.750	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.249	0.751	0.000
T40.8 Lysergide [LSD]	0.249	0.751	0.000
T40.7 Cannabis (derivatives)	0.249	0.751	0.000
T40.0 Opium	0.249	0.751	0.000
T47.6 Antidiarrhoeal drugs	0.244	0.755	0.000
T48.5 Anti-common-cold drugs	0.244	0.756	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.243	0.757	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.241	0.759	0.000
T36.9 Systemic antibiotic, unspecified	0.236	0.764	0.000
T36.7 Antifungal antibiotics, systemically used	0.236	0.764	0.000
T36.6 Rifamycins	0.236	0.764	0.000
T36.5 Aminoglycosides	0.236	0.764	0.000
T36.2 Chloramphenicol group	0.236	0.764	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.236	0.764	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.231	0.768	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.231	0.768	0.000
T47.7 Emetics	0.231	0.768	0.000
T47.5 Digestants	0.231	0.768	0.000
T47.4 Other laxatives	0.231	0.768	0.000
T47.3 Saline and osmotic laxatives	0.231	0.768	0.000
T36.4 Tetracyclines	0.229	0.770	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.226	0.774	0.000
T36.0 Penicillins	0.226	0.774	0.000
T42.3 Barbiturates	0.215	0.785	0.000
T36.3 Macrolides	0.209	0.791	0.000
T42.0 Hydantoin derivatives	0.207	0.793	0.000
T47.2 Stimulant laxatives	0.205	0.794	0.000
T42.1 Iminostilbenes	0.204	0.795	0.000
T40.6 Other and unspecified narcotics	0.202	0.798	0.000
T40.4 Other synthetic narcotics	0.198	0.802	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.191	0.809	0.000
T42.2 Succinimides and oxazolidinediones	0.191	0.809	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.185	0.815	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.181	0.819	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.180	0.820	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.162	0.838	0.000
T45.8 Other primarily systemic and haematological agents	0.162	0.838	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.162	0.838	0.000
T45.6 Fibrinolysis-affecting drugs	0.162	0.838	0.000
T45.4 Iron and its compounds	0.162	0.838	0.000
T45.3 Enzymes, not elsewhere classified	0.162	0.838	0.000
T45.0 Antiallergic and antiemetic drugs	0.159	0.841	0.000
T45.2 Vitamins, not elsewhere classified	0.145	0.854	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.131	0.869	0.000
T45.5 Anticoagulants	0.127	0.872	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.122	0.878	0.000
T42.4 Benzodiazepines	0.109	0.890	0.000
Y95 Nosocomial condition	0.000	0.974	0.026
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.000	0.992	0.008
O20.9 Haemorrhage in early pregnancy, unspecified	0.008	0.992	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.993	0.007
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.007	0.993	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.007	0.993	0.000
Y98 Lifestyle-related condition	0.000	0.994	0.006
Y97 Environmental-pollution-related condition	0.000	0.994	0.006
Y96 Work-related condition	0.000	0.994	0.006
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.000	0.994	0.006
Y91 Evidence of alcohol involvement determined by level of intoxication	0.000	0.995	0.005
Y90.6 Blood alcohol level of 120-199 mg/100 ml	0.000	0.995	0.005
Y90.9 Presence of alcohol in blood, level not specified	0.000	0.995	0.004
Y90.7 Blood alcohol level of 200-239 mg/100 ml	0.000	0.995	0.004
Y90.5 Blood alcohol level of 100-119 mg/100 ml	0.000	0.995	0.004
Y90.4 Blood alcohol level of 80-99 mg/100 ml	0.000	0.995	0.004
Y90.3 Blood alcohol level of 60-79 mg/100 ml	0.000	0.995	0.004
Y90.2 Blood alcohol level of 40-59 mg/100 ml	0.000	0.995	0.004
Y90.1 Blood alcohol level of 20-39 mg/100 ml	0.000	0.995	0.004
Y90.0 Blood alcohol level of less than 20 mg/100 ml	0.000	0.995	0.004
W19.4 Street and highway	0.004	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
Y91.3 Very severe alcohol intoxication	0.000	0.996	0.004
Y91.2 Severe alcohol intoxication	0.000	0.996	0.004
Y91.1 Moderate alcohol intoxication	0.000	0.996	0.004
Y91.0 Mild alcohol intoxication	0.000	0.996	0.004
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.996	0.004
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.004	0.996	0.000
Y90.8 Blood alcohol level of 240 mg/100 ml or more	0.000	0.996	0.003
D68.8 Other specified coagulation defects	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
N18.2 Chronic kidney disease, stage 2	0.000	0.997	0.003
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.997	0.003
M89.06 Algoneurodystrophy (Lower leg)	0.003	0.997	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.003	0.997	0.000
M89.0 Algoneurodystrophy	0.003	0.997	0.000
Y84.0 Cardiac catheterisation	0.000	0.997	0.003
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.003	0.997	0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.003	0.997	0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.003	0.997	0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.003	0.997	0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.003	0.997	0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.003	0.997	0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.003	0.997	0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.003	0.997	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.003	0.997	0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.003	0.997	0.000
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
O20.0 Threatened abortion	0.003	0.997	0.000
S89.9 Unspecified injury of lower leg	0.003	0.997	0.000
I69 Sequelae of cerebrovascular disease	0.003	0.997	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.997	0.003
Z22.5 Carrier of viral hepatitis	0.000	0.997	0.003
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.002	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.997	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.997	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.997	0.003
O69.2 Labour and delivery complicated by other cord entanglement	0.003	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
N32.3 Diverticulum of bladder	0.000	0.998	0.002
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.998	0.002
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
D24 Benign neoplasm of breast	0.000	0.998	0.002
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.998	0.002
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.998	0.000
I62 Other nontraumatic intracranial haemorrhage	0.002	0.998	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.998	0.002
I69.3 Sequelae of cerebral infarction	0.002	0.998	0.000
C32.0 Glottis	0.002	0.998	0.000
M53 Other dorsopathies, not elsewhere classified	0.002	0.998	0.000
H31.0 Chorioretinal scars	0.000	0.998	0.002
I08.8 Other multiple valve diseases	0.002	0.998	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.998	0.002
M33.1 Other dermatomyositis	0.002	0.998	0.000
C82.3 Follicular lymphoma grade IIIa	0.000	0.998	0.002
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
M53.2 Spinal instabilities	0.002	0.998	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.998	0.002
M53.9 Dorsopathy, unspecified	0.002	0.998	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.998	0.002
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.998	0.002
I62.1 Nontraumatic extradural haemorrhage	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.998	0.002
M95.0 Acquired deformity of nose	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
J93.8 Other pneumothorax	0.002	0.998	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.998	0.002
M53.22 Spinal instabilities (Cervical region)	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.000	0.998	0.002
M53.1 Cervicobrachial syndrome	0.001	0.998	0.000
M53.0 Cervicocranial syndrome	0.001	0.998	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.001	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
I25.5 Ischaemic cardiomyopathy	0.002	0.998	0.000
H31.8 Other specified disorders of choroid	0.000	0.998	0.002
K26.5 Chronic or unspecified with perforation	0.000	0.998	0.002
Q67.6 Pectus excavatum	0.002	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.002	0.998	0.000
M53.29 Spinal instabilities (Site unspecified)	0.001	0.998	0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M53.25 Spinal instabilities (Thoracolumbar region)	0.001	0.998	0.000
M53.24 Spinal instabilities (Thoracic region)	0.001	0.998	0.000
M53.23 Spinal instabilities (Cervicothoracic region)	0.001	0.998	0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.001	0.998	0.000
M53.20 Spinal instabilities (Multiple sites in spine)	0.001	0.998	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.998	0.002
H31.3 Choroidal haemorrhage and rupture	0.000	0.998	0.001
M95.2 Other acquired deformity of head	0.002	0.998	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.001	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
X60.8 Other specified place	0.001	0.998	0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
M53.26 Spinal instabilities (Lumbar region)	0.001	0.998	0.000
M53.99 Dorsopathy, unspecified (Site unspecified)	0.001	0.998	0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.001	0.998	0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.001	0.998	0.000
M53.94 Dorsopathy, unspecified (Thoracic region)	0.001	0.998	0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.001	0.998	0.000
M53.92 Dorsopathy, unspecified (Cervical region)	0.001	0.998	0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.001	0.998	0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.001	0.998	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.998	0.001
C82.5 Diffuse follicle centre lymphoma	0.000	0.998	0.001
C82.2 Large cell, follicular	0.000	0.998	0.001
E23.2 Diabetes insipidus	0.002	0.998	0.000
S89.8 Other specified injuries of lower leg	0.001	0.998	0.000
Z13.5 Special screening examination for eye and ear disorders	0.002	0.998	0.000
Z40.8 Other prophylactic surgery	0.000	0.998	0.002
S89 Other and unspecified injuries of lower leg	0.002	0.998	0.000
C82.0 Small cleaved cell, follicular	0.000	0.998	0.001
H31 Other disorders of choroid	0.000	0.998	0.002
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.998	0.001
J93.0 Spontaneous tension pneumothorax	0.001	0.998	0.000
M89.3 Hypertrophy of bone	0.001	0.998	0.000
X60.5 Trade and service area	0.001	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.000	0.999	0.001
M33.2 Polymyositis	0.001	0.999	0.000
Q65 Congenital deformities of hip	0.001	0.999	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.001	0.999	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.999	0.001
M53.09 Cervicocranial syndrome-Site unspe	0.001	0.999	0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.001	0.999	0.000
M53.07 Cervicocranial syndrome-Lumbosacral	0.001	0.999	0.000
M53.06 Cervicocranial syndrome-Lumbar	0.001	0.999	0.000
M53.05 Cervicocranial syndrome-Thoracolumbar	0.001	0.999	0.000
M53.04 Cervicocranial syndrome-Thoracic	0.001	0.999	0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.001	0.999	0.000
M53.02 Cervicocranial syndrome (Cervical region)	0.001	0.999	0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.001	0.999	0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.001	0.999	0.000
M53.19 Cervicobrachial syndrome-Site unspe	0.001	0.999	0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.001	0.999	0.000
M53.17 Cervicobrachial syndrome-Lumbosacral	0.001	0.999	0.000
M53.16 Cervicobrachial syndrome-Lumbar	0.001	0.999	0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.001	0.999	0.000
M53.14 Cervicobrachial syndrome-Thoracic	0.001	0.999	0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.001	0.999	0.000
M53.12 Cervicobrachial syndrome (Cervical region)	0.001	0.999	0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.001	0.999	0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.001	0.999	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.999	0.001
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.999	0.001
G24.9 Dystonia, unspecified	0.001	0.999	0.000
H31.9 Disorder of choroid, unspecified	0.000	0.999	0.001
M53.8 Other specified dorsopathies	0.001	0.999	0.000
D62 Acute posthaemorrhagic anaemia	0.001	0.999	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.001	0.999	0.000
B94.8 Sequelae of other specified infectious and parasitic diseases	0.001	0.999	0.000
H31.1 Choroidal degeneration	0.000	0.999	0.001
X67.9 Unspecified place	0.001	0.999	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.001	0.999	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.999	0.001
F12.1 Harmful use	0.000	0.999	0.001
S89.7 Multiple injuries of lower leg	0.001	0.999	0.000
S89.1 Other specified injuries of lower leg	0.001	0.999	0.000
S89.0 Multiple injuries of lower leg	0.001	0.999	0.000
X59.4 Street and highway	0.000	0.999	0.001
X69.9 Unspecified place	0.001	0.999	0.000
M47.94 Spondylosis, unspecified (Thoracic region)	0.000	0.999	0.001
E23.6 Other disorders of pituitary gland	0.001	0.999	0.000
H31.4 Choroidal detachment	0.000	0.999	0.001
H31.2 Hereditary choroidal dystrophy	0.000	0.999	0.001
M95.4 Acquired deformity of chest and rib	0.001	0.999	0.000
X78.0 Home	0.001	0.999	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.001	0.999	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.001	0.999	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.001	0.999	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.001	0.999	0.000
M89.34 Hypertrophy of bone (Hand)	0.001	0.999	0.000
M89.33 Hypertrophy of bone (Forearm)	0.001	0.999	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.001	0.999	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.001	0.999	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.001	0.999	0.000
E23.0 Hypopituitarism	0.001	0.999	0.000
E26.0 Primary hyperaldosteronism	0.000	0.999	0.001
I85.0 Oesophageal varices with bleeding	0.001	0.999	0.000
M95.1 Cauliflower ear	0.001	0.999	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.001	0.999	0.000
X60.2 School, other institution and public administrative area	0.001	0.999	0.000
M79.62 Pain in limb (Upper arm)	0.000	0.999	0.001
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.999	0.001
Q65.9 Congenital deformity of hip, unspecified	0.001	0.999	0.000
Q65.6 Unstable hip	0.001	0.999	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.001	0.999	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.001	0.999	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.001	0.999	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.001	0.999	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.001	0.999	0.000
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.999	0.000
X60.9 Unspecified place	0.001	0.999	0.000
X60.0 Home	0.001	0.999	0.000
X60.7 Farm	0.001	0.999	0.000
X60.6 Industrial and construction area	0.001	0.999	0.000
X60.4 Street and highway	0.001	0.999	0.000
X60.3 Sports and athletics area	0.001	0.999	0.000
X60.1 Residential institution	0.001	0.999	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.001	0.999	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.001	0.999	0.000
M53.89 Other specified dorsopathies (Site unspecified)	0.001	0.999	0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M53.87 Other specified dorsopathies (Lumbosacral region)	0.001	0.999	0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.001	0.999	0.000
M53.84 Other specified dorsopathies (Thoracic region)	0.001	0.999	0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.001	0.999	0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.001	0.999	0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.001	0.999	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.999	0.001
Z45.1 Adjustment and management of infusion pump	0.000	0.999	0.001
M89 Other disorders of bone	0.001	0.999	0.000
B94.9 Sequelae of unspecified infectious or parasitic disease	0.001	0.999	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.999	0.001
G82.5 Tetraplegia, unspecified	0.000	0.999	0.001
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.001	0.999	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.001	0.999	0.000
M95.5 Acquired deformity of pelvis	0.001	0.999	0.000
X78 Intentional self-harm by sharp object	0.001	0.999	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.001	0.999	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.001	0.999	0.000
M95.3 Acquired deformity of neck	0.001	0.999	0.000
R46.4 Slowness and poor responsiveness	0.001	0.999	0.000
M53.86 Other specified dorsopathies (Lumbar region)	0.001	0.999	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.001	0.999	0.000
C32.1 Supraglottis	0.001	0.999	0.000
G24.8 Other dystonia	0.001	0.999	0.000
H05.2 Exophthalmic conditions	0.000	0.999	0.001
X67.0 Home	0.001	0.999	0.000
C32 Malignant neoplasm of larynx	0.001	0.999	0.000
M33 Dermatopolymyositis	0.001	0.999	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.001	0.999	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.999	0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.999	0.000
K04.8 Radicular cyst	0.000	0.999	0.001
M33.9 Dermatopolymyositis, unspecified	0.001	0.999	0.000
X65.8 Other specified place	0.001	0.999	0.000
X67.8 Other specified place	0.001	0.999	0.000
X67.7 Farm	0.001	0.999	0.000
X67.6 Industrial and construction area	0.001	0.999	0.000
X67.5 Trade and service area	0.001	0.999	0.000
X67.4 Street and highway	0.001	0.999	0.000
X67.3 Sports and athletics area	0.001	0.999	0.000
X67.2 School, other institution and public administrative area	0.001	0.999	0.000
X67.1 Residential institution	0.001	0.999	0.000
X80.0 Home	0.001	0.999	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
X60.09 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics; Home; During unspecified activity	0.001	0.999	0.000
X60.08 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics, Home , While engaged in other specified activities	0.001	0.999	0.000
X60.99 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics, Unspecified place, During unspecified activity	0.001	0.999	0.000
C32.3 Laryngeal cartilage	0.001	0.999	0.000
C32.2 Subglottis	0.001	0.999	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.999	0.001
N64.8 Other specified disorders of breast	0.001	0.999	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.001	0.999	0.000
X51.8 Other specified place	0.000	0.999	0.001
X70.2 School, other institution and public administrative area	0.001	0.999	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.001	0.999	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.001	0.999	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.001	0.999	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.999	0.001
L51.9 Erythema multiforme, unspecified	0.001	0.999	0.000
M89.6 Osteopathy after poliomyelitis	0.001	0.999	0.000
M89.2 Other disorders of bone development and growth	0.001	0.999	0.000
M89.1 Epiphyseal arrest	0.001	0.999	0.000
X80 Intentional self-harm by jumping from a high place	0.001	0.999	0.000
X70 Intentional self-harm by hanging, strangulation and suffocation	0.001	0.999	0.000
X60-X84 Intentional self-harm	0.001	0.999	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.001	0.999	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.001	0.999	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.001	0.999	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.001	0.999	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.001	0.999	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.001	0.999	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.001	0.999	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.001	0.999	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.001	0.999	0.000
Q39.6 Diverticulum of oesophagus	0.001	0.999	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.999	0.000
S82.2 Fracture of shaft of tibia	0.001	0.999	0.000
X78.9 Unspecified place	0.001	0.999	0.000
X78.8 Other specified place	0.001	0.999	0.000
X78.7 Farm	0.001	0.999	0.000
X78.6 Industrial and construction area	0.001	0.999	0.000
X78.5 Trade and service area	0.001	0.999	0.000
X78.4 Street and highway	0.001	0.999	0.000
X78.3 Sports and athletics area	0.001	0.999	0.000
X78.2 School, other institution and public administrative area	0.001	0.999	0.000
X78.1 Residential institution	0.001	0.999	0.000
E23 Hypofunction and other disorders of pituitary gland	0.001	0.999	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.001	0.999	0.000
M53.82 Other specified dorsopathies (Cervical region)	0.001	0.999	0.001
C32.8 Overlapping lesion of larynx	0.001	0.999	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.999	0.001
M33.0 Juvenile dermatomyositis	0.001	0.999	0.000
Q67.8 Other congenital deformities of chest	0.001	0.999	0.000
Q67.7 Pectus carinatum	0.001	0.999	0.000
Q67.3 Plagiocephaly	0.001	0.999	0.000
Q67.2 Dolichocephaly	0.001	0.999	0.000
Q67.1 Compression facies	0.001	0.999	0.000
Q67.0 Facial asymmetry	0.001	0.999	0.000
W55.8 Other specified place	0.001	0.999	0.000
E34.8 Other specified endocrine disorders	0.000	0.999	0.001
M50.2 Other cervical disk displacement	0.001	0.999	0.000
X83 Intentional self-harm by other specified means	0.001	0.999	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.000	0.999	0.001
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations