TreeWAS – Variant ID: rs2050122

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C67 Malignant neoplasm of bladder	0.041	0.959	0.000
C67.9 Bladder, unspecified	0.040	0.960	0.000
C67.5 Bladder neck	0.038	0.962	0.000
C67.1 Dome of bladder	0.038	0.962	0.000
N90.5 Atrophy of vulva	0.000	0.964	0.036
C67.0 Trigone of bladder	0.035	0.965	0.000
C67.3 Anterior wall of bladder	0.033	0.967	0.000
C67.2 Lateral wall of bladder	0.033	0.967	0.000
L92.0 Granuloma annulare	0.000	0.967	0.033
L92 Granulomatous disorders of skin and subcutaneous tissue	0.000	0.968	0.032
C67.6 Ureteric orifice	0.032	0.968	0.000
L92.8 Other granulomatous disorders of skin and subcutaneous tissue	0.000	0.970	0.030
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.970	0.030
C67.7 Urachus	0.029	0.970	0.000
C67.8 Overlapping lesion of bladder	0.028	0.971	0.000
C67.4 Posterior wall of bladder	0.028	0.972	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.972	0.028
L92.2 Granuloma faciale [eosinophilic granuloma of skin]	0.000	0.975	0.025
L92.1 Necrobiosis lipoidica, not elsewhere classified	0.000	0.977	0.023
K82.8 Other specified diseases of gallbladder	0.016	0.984	0.000
R49.0 Dysphonia	0.000	0.985	0.015
D36.1 Peripheral nerves and autonomic nervous system	0.000	0.986	0.014
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.000	0.988	0.012
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.011	0.989	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.989	0.011
R49 Voice disturbances	0.000	0.991	0.009
R49.1 Aphonia	0.000	0.992	0.008
C18.0 Caecum	0.000	0.992	0.008
S27.0 Traumatic pneumothorax	0.007	0.993	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.007	0.993	0.000
R49.2 Hypernasality and hyponasality	0.000	0.993	0.006
C64-C68 Malignant neoplasms of urinary tract	0.007	0.993	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
R49.8 Other and unspecified voice disturbances	0.000	0.994	0.006
I42.0 Dilated cardiomyopathy	0.006	0.994	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.005	0.995	0.000
D36 Benign neoplasm of other and unspecified sites	0.000	0.995	0.005
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.005	0.995	0.000
M47.2 Other spondylosis with radiculopathy	0.005	0.995	0.000
S27 Injury of other and unspecified intrathoracic organs	0.005	0.995	0.000
C65 Malignant neoplasm of renal pelvis	0.005	0.995	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.005	0.995	0.000
C18.6 Descending colon	0.000	0.995	0.005
C18.1 Appendix	0.000	0.995	0.005
D68.0 Von Willebrand's disease	0.000	0.995	0.005
S27.2 Traumatic heamopneumothorax	0.005	0.995	0.000
C18.2 Ascending colon	0.000	0.995	0.005
C68.0 Urethra	0.005	0.995	0.000
J91 Pleural effusion in conditions classified elsewhere	0.005	0.995	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.004	0.995	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.004	0.996	0.000
D36.7 Other specified sites	0.000	0.996	0.004
D68 Other coagulation defects	0.000	0.996	0.004
D68.8 Other specified coagulation defects	0.000	0.996	0.004
M96.8 Other postprocedural musculoskeletal disorders	0.004	0.996	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.004	0.996	0.000
C18 Malignant neoplasm of colon	0.000	0.996	0.004
C68.8 Overlapping lesion of urinary organs	0.004	0.996	0.000
C68.1 Paraurethral glands	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.996	0.004
N95.2 Postmenopausal atrophic vaginitis	0.000	0.996	0.004
S27.3 Other injuries of lung	0.004	0.996	0.000
C68.9 Urinary organ, unspecified	0.004	0.996	0.000
G57.6 Lesion of plantar nerve	0.004	0.996	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.004	0.996	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.004	0.996	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.004	0.996	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.004	0.996	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.004	0.996	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.004	0.996	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.004	0.996	0.000
M95.0 Acquired deformity of nose	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.996	0.004
S27.9 Injury of unspecified intrathoracic organ	0.004	0.996	0.000
S27.7 Multiple injuries of intrathoracic organs	0.004	0.996	0.000
S27.6 Injury of pleura	0.004	0.996	0.000
S27.5 Injury of thoracic trachea	0.004	0.996	0.000
S27.4 Injury of bronchus	0.004	0.996	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.004	0.996	0.000
J31.0 Chronic rhinitis	0.000	0.996	0.004
D36.9 Benign neoplasm of unspecified site	0.000	0.996	0.004
M95.4 Acquired deformity of chest and rib	0.004	0.996	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.004	0.996	0.000
S27.8 Injury of other specified intrathoracic organs	0.004	0.996	0.000
M21.0 Valgus deformity, not elsewhere classified	0.000	0.996	0.004
C66 Malignant neoplasm of ureter	0.004	0.996	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.003	0.996	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.996	0.004
D36.0 Lymph nodes	0.000	0.996	0.003
N95.0 Postmenopausal bleeding	0.000	0.996	0.004
S27.1 Traumatic haemothorax	0.003	0.996	0.000
Y84.0 Cardiac catheterisation	0.000	0.996	0.004
M95.1 Cauliflower ear	0.003	0.996	0.000
S29.9 Unspecified injury of thorax	0.004	0.996	0.000
Z89.4 Acquired absence of foot and ankle	0.004	0.996	0.000
L72.0 Epidermal cyst	0.000	0.996	0.004
M96.0 Pseudarthrosis after fusion or arthrodesis	0.003	0.996	0.000
D68.5 Primary Thrombophilia	0.000	0.997	0.003
L72 Follicular cysts of skin and subcutaneous tissue	0.000	0.997	0.003
D68.6 Other Thrombophilia	0.000	0.997	0.003
I42.8 Other cardiomyopathies	0.003	0.997	0.000
M95.2 Other acquired deformity of head	0.003	0.997	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.003	0.997	0.000
I42 Cardiomyopathy	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.003	0.997	0.000
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.997	0.003
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.003	0.997	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.003	0.997	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.003	0.997	0.000
M95.5 Acquired deformity of pelvis	0.003	0.997	0.000
M96.5 Postradiation scoliosis	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.003	0.997	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.003	0.997	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.997	0.003
D05.9 Carcinoma in situ of breast, unspecified	0.003	0.997	0.000
M95.3 Acquired deformity of neck	0.003	0.997	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.003	0.997	0.000
M96.4 Postsurgical lordosis	0.003	0.997	0.000
M96.3 Postlaminectomy kyphosis	0.003	0.997	0.000
M96.2 Postradiation kyphosis	0.003	0.997	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.003	0.997	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.997	0.003
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.997	0.003
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.997	0.003
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.997	0.003
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.997	0.003
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.997	0.003
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.000	0.997	0.003
K62.6 Ulcer of anus and rectum	0.003	0.997	0.000
M54.56 Low back pain (Lumbar region)	0.003	0.997	0.000
S29 Other and unspecified injuries of thorax	0.003	0.997	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.003	0.997	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.003	0.997	0.000
C18.5 Splenic flexure	0.000	0.997	0.003
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.003	0.997	0.000
N36.8 Other specified disorders of urethra	0.003	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.003	0.997	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.003	0.997	0.000
K82 Other diseases of gallbladder	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.997	0.003
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
L72.2 Steatocystoma multiplex	0.000	0.997	0.003
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
C18.8 Overlapping lesion of colon	0.000	0.997	0.003
J31.2 Chronic pharyngitis	0.000	0.997	0.003
K82.4 Cholesterolosis of gallbladder	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
C77.9 Lymph node, unspecified	0.000	0.997	0.003
I42.4 Endocardial fibroelastosis	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.003	0.997	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.997	0.003
S92.1 Fracture of talus	0.003	0.997	0.000
J31.1 Chronic nasopharyngitis	0.000	0.997	0.003
S92.9 Fracture of foot, unspecified	0.002	0.997	0.000
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.002	0.997	0.000
E03.8 Other specified hypothyroidism	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.002	0.997	0.000
D41.4 Bladder	0.003	0.997	0.000
I37.1 Pulmonary valve insufficiency	0.002	0.997	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.002
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.997	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
N95 Menopausal and other perimenopausal disorders	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S20-S29 Injuries to the thorax	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.998	0.002
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
J81 Pulmonary oedema	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
I05.0 Mitral stenosis	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.000	0.998	0.002
O82.1 Delivery by emergency Caesarean section	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
K82.0 Obstruction of gallbladder	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
K82.2 Perforation of gallbladder	0.002	0.998	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.998	0.002
O82 Single delivery by Caesarean section	0.000	0.998	0.002
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
H52.1 Myopia	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.998	0.002
I38 Endocarditis, valve unspecified	0.002	0.998	0.000
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.998	0.002
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
I05.9 Mitral valve disease, unspecified	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
M99 Biomechanical lesions, not elsewhere classified	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
O69.2 Labour and delivery complicated by other cord entanglement	0.000	0.998	0.002
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
I05.2 Mitral stenosis with insufficiency	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.002
O69.9 Labour and delivery complicated by cord complication, unspecified	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
C18.3 Hepatic flexure	0.000	0.998	0.002
I05.1 Rheumatic mitral insufficiency	0.002	0.998	0.000
N80.9 Endometriosis, unspecified	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.000	0.998	0.002
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.998	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.998	0.002
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
K09.0 Developmental odontogenic cysts	0.000	0.998	0.002
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.002	0.998	0.000
S26 Injury of heart	0.002	0.998	0.000
S25 Injury of blood vessels of thorax	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S24 Injury of nerves and spinal cord at thorax level	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.002
H58.8 Visual disturbances in diseases classified elsewhere	0.000	0.998	0.002
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
A08.4 Viral intestinal infection, unspecified	0.000	0.998	0.002
N84.0 Polyp of corpus uteri	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
D84 Other immunodeficiencies	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
I51.8 Other ill-defined heart diseases	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
I51.7 Cardiomegaly	0.002	0.998	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
M99.8 Other biomechanical lesions	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.000	0.998	0.002
O82.2 Delivery by Caesarean hysterectomy	0.000	0.998	0.002
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
I37 Pulmonary valve disorders	0.002	0.998	0.000
I51.9 Heart disease, unspecified	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.000	0.998	0.002
I51 Complications and ill-defined descriptions of heart disease	0.002	0.998	0.000
J80 Adult respiratory distress syndrome	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.998	0.002
I05.8 Other mitral valve diseases	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
M99.9 Biomechanical lesion, unspecified	0.002	0.998	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.4 Connective tissue stenosis of neural canal	0.002	0.998	0.000
M99.3 Osseous stenosis of neural canal	0.002	0.998	0.000
M99.2 Subluxation stenosis of neural canal	0.002	0.998	0.000
M99.1 Subluxation complex (vertebral)	0.002	0.998	0.000
M99.0 Segmental and somatic dysfunction	0.002	0.998	0.000
S21.0 Open wound of breast	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
O69.8 Labour and delivery complicated by other cord complications	0.000	0.998	0.002
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.000	0.998	0.002
K82.3 Fistula of gallbladder	0.002	0.998	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.000	0.998	0.002
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
M21.4 Flat foot [pes planus] (acquired)	0.000	0.998	0.002
R73.9 Hyperglycaemia, unspecified	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.000	0.998	0.002
D84.1 Defects in the complement system	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.000	0.998	0.002
S21.1 Open wound of front wall of thorax	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.000	0.998	0.002
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
M99.83 Other biomechanical lesions (Lumbar region)	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
I51.5 Myocardial degeneration	0.002	0.998	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.001	0.998	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.000	0.998	0.002
O69.4 Labour and delivery complicated by vasa praevia	0.000	0.998	0.002
O69.3 Labour and delivery complicated by short cord	0.000	0.998	0.002
S23.5 Sprain and strain of other and unspecified parts of thorax	0.002	0.998	0.000
S23.4 Sprain and strain of ribs and sternum	0.002	0.998	0.000
S23.3 Sprain and strain of thoracic spine	0.002	0.998	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.002	0.998	0.000
S23.1 Dislocation of thoracic vertebra	0.002	0.998	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
S21.8 Open wound of other parts of thorax	0.002	0.998	0.000
S21.7 Multiple open wounds of thoracic wall	0.002	0.998	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.002	0.998	0.000
S25.8 Injury of other blood vessels of thorax	0.002	0.998	0.000
S25.7 Injury of multiple blood vessels of thorax	0.002	0.998	0.000
S25.5 Injury of intercostal blood vessels	0.002	0.998	0.000
S25.4 Injury of pulmonary blood vessels	0.002	0.998	0.000
S25.3 Injury of innominate or subclavian vein	0.002	0.998	0.000
S25.2 Injury of superior vena cava	0.002	0.998	0.000
S25.1 Injury of innominate or subclavian artery	0.002	0.998	0.000
S25.0 Injury of thoracic aorta	0.002	0.998	0.000
S26.9 Injury of heart, unspecified	0.002	0.998	0.000
S26.8 Other injuries of heart	0.002	0.998	0.000
S26.0 Injury of heart with haemopericardium	0.002	0.998	0.000
S28.1 Traumatic amputation of part of thorax	0.002	0.998	0.000
S28.0 Crushed chest	0.002	0.998	0.000
H50 Other strabismus	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.998	0.000
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
S24.6 Injury of unspecified nerve of thorax	0.001	0.998	0.000
S24.5 Injury of other nerves of thorax	0.001	0.998	0.000
S24.4 Injury of thoracic sympathetic nerves	0.001	0.998	0.000
S24.3 Injury of peripheral nerves of thorax	0.001	0.998	0.000
S24.2 Injury of nerve root of thoracic spine	0.001	0.998	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.001	0.998	0.000
D81 Combined immunodeficiencies	0.000	0.998	0.002
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.998	0.002
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
I37.0 Pulmonary valve stenosis	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.998	0.002
I51.6 Cardiovascular disease, unspecified	0.002	0.998	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.001	0.998	0.000
M99.5 Intervertebral disk stenosis of neural canal	0.001	0.998	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000
S21.2 Open wound of back wall of thorax	0.001	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.000	0.998	0.002
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
I31.0 Chronic adhesive pericarditis	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.998	0.000
M99.89 Other biomechanical lesions (Abdomen and other)	0.001	0.998	0.000
M99.88 Other biomechanical lesions (Rib cage)	0.001	0.998	0.000
M99.87 Other biomechanical lesions (Upper extremity)	0.001	0.998	0.000
M99.86 Other biomechanical lesions (Lower extremity)	0.001	0.998	0.000
M99.85 Other biomechanical lesions (Pelvic region)	0.001	0.998	0.000
M99.84 Other biomechanical lesions (Sacral region)	0.001	0.998	0.000
M99.82 Other biomechanical lesions (Thoracic region)	0.001	0.998	0.000
M99.80 Other biomechanical lesions (Head region)	0.001	0.998	0.000
C18.4 Transverse colon	0.000	0.998	0.001
D23.3 Skin of other and unspecified parts of face	0.002	0.998	0.000
I37.9 Pulmonary valve disorder, unspecified	0.001	0.998	0.000
I37.8 Other pulmonary valve disorders	0.001	0.998	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.001	0.998	0.000
K31.8 Other specified diseases of stomach and duodenum	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.002	0.998	0.000
H50.2 Vertical strabismus	0.002	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.998	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.002	0.998	0.000
M99.09 Segmental and somatic dysfunction (Abdomen and other)	0.001	0.998	0.000
M99.08 Segmental and somatic dysfunction (Rib cage)	0.001	0.998	0.000
M99.07 Segmental and somatic dysfunction (Upper extremity)	0.001	0.998	0.000
M99.06 Segmental and somatic dysfunction (Lower extremity)	0.001	0.998	0.000
M99.05 Segmental and somatic dysfunction (Pelvic region)	0.001	0.998	0.000
M99.04 Segmental and somatic dysfunction (Sacral region)	0.001	0.998	0.000
M99.03 Segmental and somatic dysfunction (Lumbar region)	0.001	0.998	0.000
M99.02 Segmental and somatic dysfunction (Thoracic region)	0.001	0.998	0.000
M99.01 Segmental and somatic dysfunction (Cervical region)	0.001	0.998	0.000
M99.00 Segmental and somatic dysfunction (Head region)	0.001	0.998	0.000
M99.19 Subluxation complex (vertebral) (Abdomen and other)	0.001	0.998	0.000
M99.18 Subluxation complex (vertebral) (Rib cage)	0.001	0.998	0.000
M99.17 Subluxation complex (vertebral) (Upper extremity)	0.001	0.998	0.000
M99.16 Subluxation complex (vertebral) (Lower extremity)	0.001	0.998	0.000
M99.15 Subluxation complex (vertebral) (Pelvic region)	0.001	0.998	0.000
M99.14 Subluxation complex (vertebral) (Sacral region)	0.001	0.998	0.000
M99.13 Subluxation complex (vertebral) (Lumbar region)	0.001	0.998	0.000
M99.12 Subluxation complex (vertebral) (Thoracic region)	0.001	0.998	0.000
M99.11 Subluxation complex (vertebral) (Cervical region)	0.001	0.998	0.000
M99.10 Subluxation complex (vertebral) (Head region)	0.001	0.998	0.000
M99.29 Subluxation stenosis of neural canal-Abdomen/other	0.001	0.998	0.000
M99.28 Subluxation stenosis of neural canal-Rib cage	0.001	0.998	0.000
M99.27 Subluxation stenosis of neural canal-Upper extremity	0.001	0.998	0.000
M99.26 Subluxation stenosis of neural canal-Lower extremity	0.001	0.998	0.000
M99.25 Subluxation stenosis of neural canal (Pelvic region)	0.001	0.998	0.000
M99.24 Subluxation stenosis of neural canal (Sacral region)	0.001	0.998	0.000
M99.23 Subluxation stenosis of neural canal (Lumbar region)	0.001	0.998	0.000
M99.22 Subluxation stenosis of neural canal (Thoracic region)	0.001	0.998	0.000
M99.21 Subluxation stenosis of neural canal (Cervical region)	0.001	0.998	0.000
M99.20 Subluxation stenosis of neural canal (Head region)	0.001	0.998	0.000
M99.39 Osseous stenosis of neural canal-Abdomen/other	0.001	0.998	0.000
M99.38 Osseous stenosis of neural canal-Rib cage	0.001	0.998	0.000
M99.37 Osseous stenosis of neural canal-Upper extremity	0.001	0.998	0.000
M99.36 Osseous stenosis of neural canal-Lower extremity	0.001	0.998	0.000
M99.35 Osseous stenosis of neural canal (Pelvic region)	0.001	0.998	0.000
M99.34 Osseous stenosis of neural canal (Sacral region)	0.001	0.998	0.000
M99.33 Osseous stenosis of neural canal (Lumbar region)	0.001	0.998	0.000
M99.32 Osseous stenosis of neural canal (Thoracic region)	0.001	0.998	0.000
M99.31 Osseous stenosis of neural canal (Cervical region)	0.001	0.998	0.000
M99.30 Osseous stenosis of neural canal (Head region)	0.001	0.998	0.000
M99.49 Connective tissue stenosis of neural canal-Abdomen/other	0.001	0.998	0.000
M99.48 Connective tissue stenosis of neural canal-Rib cage	0.001	0.998	0.000
M99.47 Connective tissue stenosis of neural canal-Upper extremity	0.001	0.998	0.000
M99.46 Connective tissue stenosis of neural canal-Lower extremity	0.001	0.998	0.000
M99.45 Connective tissue stenosis of neural canal (Pelvic region)	0.001	0.998	0.000
M99.44 Connective tissue stenosis of neural canal (Sacral region)	0.001	0.998	0.000
M99.43 Connective tissue stenosis of neural canal (Lumbar region)	0.001	0.998	0.000
M99.42 Connective tissue stenosis of neural canal (Thoracic region)	0.001	0.998	0.000
M99.41 Connective tissue stenosis of neural canal (Cervical region)	0.001	0.998	0.000
M99.40 Connective tissue stenosis of neural canal (Head region)	0.001	0.998	0.000
M99.69 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.68 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.67 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.66 Osseous and subluxation stenosis of intervertebral foramina	0.001	0.998	0.000
M99.65 Osseous and subluxation stenosis of intervertebral foramina (Pelvic region)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations