TreeWAS – Variant ID: rs2069837

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C67.9 Bladder, unspecified	0.000	0.942	0.058
C67 Malignant neoplasm of bladder	0.000	0.957	0.043
C67.6 Ureteric orifice	0.000	0.962	0.038
C67.2 Lateral wall of bladder	0.000	0.963	0.037
C67.1 Dome of bladder	0.000	0.968	0.032
C67.8 Overlapping lesion of bladder	0.000	0.969	0.031
C67.7 Urachus	0.000	0.969	0.031
C67.3 Anterior wall of bladder	0.000	0.969	0.031
C67.0 Trigone of bladder	0.000	0.971	0.029
C67.5 Bladder neck	0.000	0.971	0.029
C67.4 Posterior wall of bladder	0.000	0.973	0.027
I35.0 Aortic (valve) stenosis	0.000	0.990	0.010
I35.1 Aortic (valve) insufficiency	0.000	0.990	0.010
I35 Nonrheumatic aortic valve disorders	0.000	0.990	0.010
C64-C68 Malignant neoplasms of urinary tract	0.000	0.991	0.009
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.991	0.009
Z13.9 Special screening examination, unspecified	0.000	0.992	0.008
I35.9 Aortic valve disorder, unspecified	0.000	0.992	0.008
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.992	0.008
Z85.4 Personal history of malignant neoplasm of genital organs	0.000	0.992	0.008
Z85.6 Personal history of leukaemia	0.000	0.993	0.007
Z85 Personal history of malignant neoplasm	0.000	0.993	0.007
C68 Malignant neoplasm of other and unspecified urinary organs	0.000	0.993	0.007
C65 Malignant neoplasm of renal pelvis	0.000	0.993	0.007
C66 Malignant neoplasm of ureter	0.000	0.993	0.006
I35.8 Other aortic valve disorders	0.000	0.994	0.006
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.000	0.994	0.006
D23.1 Skin of eyelid, including canthus	0.000	0.994	0.006
Z85.9 Personal history of malignant neoplasm, unspecified	0.000	0.994	0.006
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.994	0.006
Z85.0 Personal history of malignant neoplasm of digestive organs	0.000	0.995	0.005
S61.0 Open wound of finger(s) without damage to nail	0.000	0.995	0.005
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.995	0.005
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.000	0.995	0.005
C68.9 Urinary organ, unspecified	0.000	0.995	0.005
C68.8 Overlapping lesion of urinary organs	0.000	0.995	0.005
C68.1 Paraurethral glands	0.000	0.995	0.005
C68.0 Urethra	0.000	0.995	0.005
N31.8 Other neuromuscular dysfunction of bladder	0.005	0.995	0.000
K82.8 Other specified diseases of gallbladder	0.005	0.995	0.000
T42.4 Benzodiazepines	0.000	0.995	0.005
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.995	0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.995	0.005
M10.99 Gout, unspecified (Site unspecified)	0.000	0.995	0.005
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.995	0.005
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.995	0.005
N13.3 Other and unspecified hydronephrosis	0.000	0.996	0.004
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.996	0.004
S61.1 Open wound of finger(s) with damage to nail	0.000	0.996	0.004
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.004	0.996	0.000
Z85.02 Personal history of malignant neoplasm of stomach	0.000	0.996	0.004
T39.1 4-Aminophenol derivatives	0.000	0.996	0.004
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.996	0.004
T43.9 Psychotropic drug, unspecified	0.000	0.996	0.004
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.996	0.004
T43.6 Psychostimulants with abuse potential	0.000	0.996	0.004
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.996	0.004
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.996	0.004
S92.00 Fracture of calcaneus (closed)	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.996	0.004
T43.2 Other and unspecified antidepressants	0.000	0.996	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.996	0.004
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.996	0.004
D22.5 Melanocytic naevi of trunk	0.000	0.996	0.004
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.996	0.004
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.996	0.004
T42.3 Barbiturates	0.000	0.996	0.004
T42.2 Succinimides and oxazolidinediones	0.000	0.996	0.004
T42.1 Iminostilbenes	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.000	0.996	0.004
E11.3 With ophthalmic complications	0.004	0.996	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.996	0.003
H36.0 Diabetic retinopathy	0.004	0.996	0.000
N13.4 Hydroureter	0.000	0.996	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.004	0.996	0.000
T39.0 Salicylates	0.000	0.996	0.003
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.996	0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.996	0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.996	0.003
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.996	0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.996	0.003
N13 Obstructive and reflux uropathy	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.997	0.003
D22.4 Melanocytic naevi of scalp and neck	0.000	0.997	0.003
S61 Open wound of wrist and hand	0.000	0.997	0.003
D23.5 Skin of trunk	0.000	0.997	0.003
T36 Poisoning by systemic antibiotics	0.000	0.997	0.003
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.997	0.003
M10.9 Gout, unspecified	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.003
T39.2 Pyrazolone derivatives	0.000	0.997	0.003
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.997	0.003
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.997	0.003
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.997	0.003
S61.7 Multiple open wounds of wrist and hand	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
I24.8 Other forms of acute ischaemic heart disease	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
S92.0 Fracture of calcaneus	0.003	0.997	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.000	0.997	0.003
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.997	0.003
T50.8 Diagnostic agents	0.000	0.997	0.003
T50.7 Analeptics and opioid receptor antagonists	0.000	0.997	0.003
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.997	0.003
T50.5 Appetite depressants	0.000	0.997	0.003
T50.4 Drugs affecting uric acid metabolism	0.000	0.997	0.003
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.997	0.003
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.997	0.003
T50.1 Loop [high-ceiling] diuretics	0.000	0.997	0.003
T50.0 Mineralocorticoids and their antagonists	0.000	0.997	0.003
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
H25.9 Senile cataract, unspecified	0.000	0.997	0.003
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.997	0.003
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.997	0.003
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.997	0.003
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.997	0.003
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.997	0.003
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.997	0.003
T44.0 Anticholinesterase agents	0.000	0.997	0.003
M10.96 Gout, unspecified (Lower leg)	0.000	0.997	0.003
D22 Melanocytic naevi	0.000	0.997	0.003
E16.2 Hypoglycaemia, unspecified	0.003	0.997	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.003	0.997	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.003	0.997	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.997	0.003
N13.6 Pyonephrosis	0.000	0.997	0.003
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.997	0.003
T38.9 Other and unspecified hormone antagonists	0.000	0.997	0.003
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.997	0.003
T38.7 Androgens and anabolic congeners	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.997	0.003
T38.5 Other oestrogens and progestogens	0.000	0.997	0.003
T38.4 Oral contraceptives	0.000	0.997	0.003
T38.2 Antithyroid drugs	0.000	0.997	0.003
T38.1 Thyroid hormones and substitutes	0.000	0.997	0.003
T38.0 Glucocorticoids and synthetic analogues	0.000	0.997	0.003
T40.4 Other synthetic narcotics	0.000	0.997	0.003
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.997	0.003
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.997	0.003
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.003
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.997	0.003
T37.5 Antiviral drugs	0.000	0.997	0.003
T37.4 Anthelminthics	0.000	0.997	0.003
T37.3 Other antiprotozoal drugs	0.000	0.997	0.003
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.997	0.003
T37.1 Antimycobacterial drugs	0.000	0.997	0.003
T37.0 Sulphonamides	0.000	0.997	0.003
T41.5 Therapeutic gases	0.000	0.997	0.003
T41.4 Anaesthetic, unspecified	0.000	0.997	0.003
T41.3 Local anaesthetics	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.000	0.997	0.003
T41.1 Intravenous anaesthetics	0.000	0.997	0.003
T41.0 Inhaled anaesthetics	0.000	0.997	0.003
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.997	0.003
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.997	0.003
T47.7 Emetics	0.000	0.997	0.003
T47.6 Antidiarrhoeal drugs	0.000	0.997	0.003
T47.5 Digestants	0.000	0.997	0.003
T47.4 Other laxatives	0.000	0.997	0.003
T47.3 Saline and osmotic laxatives	0.000	0.997	0.003
T47.2 Stimulant laxatives	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.997	0.003
T47.0 Histamine H(2)-receptor antagonists	0.000	0.997	0.003
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.997	0.003
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.997	0.003
T48.5 Anti-common-cold drugs	0.000	0.997	0.003
T48.4 Expectorants	0.000	0.997	0.003
T48.3 Antitussives	0.000	0.997	0.003
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.997	0.003
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.997	0.003
T48.0 Oxytocic drugs	0.000	0.997	0.003
T49.9 Topical agent, unspecified	0.000	0.997	0.003
T49.8 Other topical agents	0.000	0.997	0.003
T49.7 Dental drugs, topically applied	0.000	0.997	0.003
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.997	0.003
T49.5 Ophthalmological drugs and preparations	0.000	0.997	0.003
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.997	0.003
T49.3 Emollients, demulcents and protectants	0.000	0.997	0.003
T49.2 Local astringents and local detergents	0.000	0.997	0.003
T49.1 Antipruritics	0.000	0.997	0.003
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.997	0.003
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.997	0.003
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.997	0.003
T46.7 Peripheral vasodilators	0.000	0.997	0.003
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.997	0.003
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
T46.1 Calcium-channel blockers	0.000	0.997	0.003
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.997	0.003
D23 Other benign neoplasms of skin	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.000	0.997	0.002
T36.8 Other systemic antibiotics	0.000	0.997	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.997	0.002
T36.6 Rifamycins	0.000	0.997	0.002
T36.5 Aminoglycosides	0.000	0.997	0.002
T36.4 Tetracyclines	0.000	0.997	0.002
T36.3 Macrolides	0.000	0.997	0.002
T36.2 Chloramphenicol group	0.000	0.997	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.997	0.002
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.997	0.003
M10.98 Gout, unspecified (Other)	0.000	0.997	0.002
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
M10.93 Gout, unspecified (Forearm)	0.000	0.997	0.002
M10.92 Gout, unspecified (Upper arm)	0.000	0.997	0.002
M10.91 Gout, unspecified (Shoulder region)	0.000	0.997	0.002
T36.0 Penicillins	0.000	0.997	0.002
M10.90 Gout, unspecified (Multiple sites)	0.000	0.997	0.002
D23.4 Skin of scalp and neck	0.000	0.997	0.003
T51.0 Ethanol	0.000	0.997	0.003
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.997	0.002
T45.8 Other primarily systemic and haematological agents	0.000	0.997	0.002
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.997	0.002
T45.6 Fibrinolysis-affecting drugs	0.000	0.997	0.002
T45.4 Iron and its compounds	0.000	0.997	0.002
T45.3 Enzymes, not elsewhere classified	0.000	0.997	0.002
T45.2 Vitamins, not elsewhere classified	0.000	0.997	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.997	0.002
D23.7 Skin of lower limb, including hip	0.000	0.997	0.003
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.997	0.002
T40.8 Lysergide [LSD]	0.000	0.997	0.002
T40.7 Cannabis (derivatives)	0.000	0.997	0.002
T40.5 Cocaine	0.000	0.997	0.002
T40.3 Methadone	0.000	0.997	0.002
T40.1 Heroin	0.000	0.997	0.002
T40.0 Opium	0.000	0.997	0.002
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.002	0.997	0.000
S91 Open wound of ankle and foot	0.002	0.997	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
T45.5 Anticoagulants	0.000	0.998	0.002
C50.8 Overlapping lesion of breast	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
M10.94 Gout, unspecified (Hand)	0.000	0.998	0.002
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.998	0.002
S42.20 Fracture of upper end of humerus (closed)	0.000	0.998	0.002
T40.6 Other and unspecified narcotics	0.000	0.998	0.002
S92 Fracture of foot, except ankle	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
D23.9 Skin, unspecified	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
Z95.2 Presence of prosthetic heart valve	0.000	0.998	0.002
D22.9 Melanocytic naevi, unspecified	0.000	0.998	0.002
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
S69.9 Unspecified injury of wrist and hand	0.000	0.998	0.002
D23.0 Skin of lip	0.000	0.998	0.002
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.000	0.998	0.002
S61.9 Open wound of wrist and hand, part unspecified	0.000	0.998	0.002
Y40.0 Penicillins	0.000	0.998	0.002
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
T51 Toxic effect of alcohol	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
H36 Retinal disorders in diseases classified elsewhere	0.002	0.998	0.000
D22.0 Melanocytic naevi of lip	0.000	0.998	0.002
D73.0 Hyposplenism	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.000	0.998	0.002
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.998	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.001
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
K59.0 Constipation	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
D23.2 Skin of ear and external auricular canal	0.001	0.998	0.001
N60.8 Other benign mammary dysplasias	0.002	0.998	0.000
E16 Other disorders of pancreatic internal secretion	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
S92.50 Fracture of other toe (closed)	0.001	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
S92.41 Fracture of great toe (open)	0.001	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.998	0.000
T51.8 Other alcohols	0.000	0.998	0.001
T51.3 Fusel oil	0.000	0.998	0.001
T51.2 2-Propanol	0.000	0.998	0.001
T51.1 Methanol	0.000	0.998	0.001
H36.8 Other retinal disorders in diseases classified elsewhere	0.001	0.998	0.000
S92.40 Fracture of great toe (closed)	0.001	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.001	0.998	0.000
K82 Other diseases of gallbladder	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.001	0.998	0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
G43.9 Migraine, unspecified	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
M10 Gout	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.001	0.998	0.000
D23.3 Skin of other and unspecified parts of face	0.000	0.998	0.002
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.001	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.001	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.001	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.001	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.001	0.998	0.000
S94.1 Injury of medial plantar nerve	0.001	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.001	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.001	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.001	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.001	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.001	0.998	0.000
S95.1 Injury of plantar artery of foot	0.001	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.001	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.001	0.998	0.000
S97.1 Crushing injury of toe(s)	0.001	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.001	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.001	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.001	0.998	0.000
S98.1 Traumatic amputation of one toe	0.001	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.001	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.001	0.998	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.001	0.998	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.001	0.998	0.000
E16.4 Abnormal secretion of gastrin	0.001	0.998	0.000
E16.3 Increased secretion of glucagon	0.001	0.998	0.000
E16.1 Other hypoglycaemia	0.001	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.001	0.998	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.002	0.998	0.000
D73 Diseases of spleen	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.001	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.000
N73.6 Female pelvic peritoneal adhesions	0.002	0.998	0.000
C83.3 Large cell (diffuse)	0.000	0.999	0.001
S90.7 Multiple superficial injuries of ankle and foot	0.001	0.999	0.000
S90.3 Contusion of other and unspecified parts of foot	0.001	0.999	0.000
S90.2 Contusion of toe(s) with damage to nail	0.001	0.999	0.000
S90.1 Contusion of toe(s) without damage to nail	0.001	0.999	0.000
S90.0 Contusion of ankle	0.001	0.999	0.000
H52.1 Myopia	0.000	0.999	0.001
S90.8 Other superficial injuries of ankle and foot	0.001	0.999	0.000
S69 Other and unspecified injuries of wrist and hand	0.000	0.999	0.001
K82.2 Perforation of gallbladder	0.001	0.999	0.000
D73.5 Infarction of spleen	0.001	0.999	0.000
K82.3 Fistula of gallbladder	0.001	0.999	0.000
K82.0 Obstruction of gallbladder	0.001	0.999	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.000	0.999	0.001
R04.2 Haemoptysis	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
K82.1 Hydrops of gallbladder	0.001	0.999	0.000
M10.4 Other secondary gout	0.000	0.999	0.001
M10.3 Gout due to impairment of renal function	0.000	0.999	0.001
M10.2 Drug-induced gout	0.000	0.999	0.001
M10.1 Lead-induced gout	0.000	0.999	0.001
M10.0 Idiopathic gout	0.000	0.999	0.001
S61.8 Open wound of other parts of wrist and hand	0.000	0.999	0.001
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.000	0.999	0.001
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.000	0.999	0.001
D73.9 Disease of spleen, unspecified	0.001	0.999	0.000
D73.4 Cyst of spleen	0.001	0.999	0.000
D73.3 Abscess of spleen	0.001	0.999	0.000
D73.2 Chronic congestive splenomegaly	0.001	0.999	0.000
D73.1 Hypersplenism	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.001	0.999	0.000
D68.0 Von Willebrand's disease	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.001	0.999	0.000
O20.8 Other haemorrhage in early pregnancy	0.001	0.999	0.000
D68 Other coagulation defects	0.001	0.999	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.999	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.001	0.999	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.000	0.999	0.001
H92.1 Otorrhoea	0.000	0.999	0.001
S69.8 Other specified injuries of wrist and hand	0.000	0.999	0.001
S69.7 Multiple injuries of wrist and hand	0.000	0.999	0.001
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.000	0.999	0.001
Z08 Follow-up examination after treatment for malignant neoplasm	0.000	0.999	0.001
G45.2 Multiple and bilateral precerebral artery syndromes	0.000	0.999	0.001
G45.1 Carotid artery syndrome (hemispheric)	0.000	0.999	0.001
G45.0 Vertebro-basilar artery syndrome	0.000	0.999	0.001
K82.9 Disease of gallbladder, unspecified	0.001	0.999	0.000
D69.2 Other nonthrombocytopenic purpura	0.001	0.999	0.000
M10.09 Idiopathic gout (Site unspecified)	0.000	0.999	0.001
M10.08 Idiopathic gout (Other)	0.000	0.999	0.001
M10.07 Idiopathic gout (Ankle and foot)	0.000	0.999	0.001
M10.06 Idiopathic gout (Lower leg)	0.000	0.999	0.001
M10.05 Idiopathic gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.04 Idiopathic gout (Hand)	0.000	0.999	0.001
M10.03 Idiopathic gout (Forearm)	0.000	0.999	0.001
M10.02 Idiopathic gout (Upper arm)	0.000	0.999	0.001
M10.01 Idiopathic gout (Shoulder region)	0.000	0.999	0.001
M10.00 Idiopathic gout (Multiple sites)	0.000	0.999	0.001
M10.19 Lead-induced gout (Site unspecified)	0.000	0.999	0.001
M10.18 Lead-induced gout (Other)	0.000	0.999	0.001
M10.17 Lead-induced gout (Ankle and foot)	0.000	0.999	0.001
M10.16 Lead-induced gout (Lower leg)	0.000	0.999	0.001
M10.15 Lead-induced gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.14 Lead-induced gout (Hand)	0.000	0.999	0.001
M10.13 Lead-induced gout (Forearm)	0.000	0.999	0.001
M10.12 Lead-induced gout (Upper arm)	0.000	0.999	0.001
M10.11 Lead-induced gout (Shoulder region)	0.000	0.999	0.001
M10.10 Lead-induced gout (Multiple sites)	0.000	0.999	0.001
M10.29 Drug-induced gout (Site unspecified)	0.000	0.999	0.001
M10.28 Drug-induced gout (Other)	0.000	0.999	0.001
M10.27 Drug-induced gout (Ankle and foot)	0.000	0.999	0.001
M10.26 Drug-induced gout (Lower leg)	0.000	0.999	0.001
M10.25 Drug-induced gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.24 Drug-induced gout (Hand)	0.000	0.999	0.001
M10.23 Drug-induced gout (Forearm)	0.000	0.999	0.001
M10.22 Drug-induced gout (Upper arm)	0.000	0.999	0.001
M10.21 Drug-induced gout (Shoulder region)	0.000	0.999	0.001
M10.20 Drug-induced gout (Multiple sites)	0.000	0.999	0.001
M10.39 Gout due to impairment of renal function (Site unspecified)	0.000	0.999	0.001
M10.38 Gout due to impairment of renal function (Other)	0.000	0.999	0.001
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.000	0.999	0.001
M10.36 Gout due to impairment of renal function (Lower leg)	0.000	0.999	0.001
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.000	0.999	0.001
M10.34 Gout due to impairment of renal function (Hand)	0.000	0.999	0.001
M10.33 Gout due to impairment of renal function (Forearm)	0.000	0.999	0.001
M10.32 Gout due to impairment of renal function (Upper arm)	0.000	0.999	0.001
M10.31 Gout due to impairment of renal function (Shoulder region)	0.000	0.999	0.001
M10.30 Gout due to impairment of renal function (Multiple sites)	0.000	0.999	0.001
M10.49 Other secondary gout (Site unspecified)	0.000	0.999	0.001
M10.48 Other secondary gout (Other)	0.000	0.999	0.001
M10.47 Other secondary gout (Ankle and foot)	0.000	0.999	0.001
M10.46 Other secondary gout (Lower leg)	0.000	0.999	0.001
M10.45 Other secondary gout (Pelvic region and thigh)	0.000	0.999	0.001
M10.44 Other secondary gout (Hand)	0.000	0.999	0.001
M10.43 Other secondary gout (Forearm)	0.000	0.999	0.001
M10.42 Other secondary gout (Upper arm)	0.000	0.999	0.001
M10.41 Other secondary gout (Shoulder region)	0.000	0.999	0.001
M10.40 Other secondary gout (Multiple sites)	0.000	0.999	0.001
M40.56 Lordosis, unspecified (Lumbar region)	0.001	0.999	0.000
D68.8 Other specified coagulation defects	0.001	0.999	0.000
H92.0 Otalgia	0.000	0.999	0.001
I21.4 Acute subendocardial myocardial infarction	0.001	0.999	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
M43.06 Spondylolysis (Lumbar region)	0.001	0.999	0.000
S42.2 Fracture of upper end of humerus	0.000	0.999	0.001
D68.6 Other Thrombophilia	0.001	0.999	0.000
D68.4 Acquired coagulation factor deficiency	0.001	0.999	0.000
D68.1 Hereditary factor XI deficiency	0.001	0.999	0.000
D69.5 Secondary thrombocytopenia	0.001	0.999	0.000
G45.4 Transient global amnesia	0.000	0.999	0.001
G45.3 Amaurosis fugax	0.000	0.999	0.001
Z95.3 Presence of xenogenic heart valve	0.000	0.999	0.001
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.999	0.001
D69.0 Allergic purpura	0.001	0.999	0.000
L28.0 Lichen simplex chronicus	0.000	0.999	0.001
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.999	0.001
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.999	0.001
S92.30 Fracture of metatarsal bone (closed)	0.001	0.999	0.000
E88.8 Other specified metabolic disorders	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations