TreeWAS – Variant ID: rs2071449

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.010	0.990
I10-I15 Hypertensive diseases	0.000	0.682	0.318
S72.00 Fracture of neck of femur (closed)	0.302	0.698	0.000
I11 Hypertensive heart disease	0.000	0.728	0.272
I13 Hypertensive heart and renal disease	0.000	0.770	0.230
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.774	0.226
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.783	0.217
I15 Secondary hypertension	0.000	0.800	0.200
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.833	0.166
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.835	0.165
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.835	0.165
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.835	0.165
I15.0 Renovascular hypertension	0.000	0.852	0.147
I15.8 Other secondary hypertension	0.000	0.856	0.143
I15.2 Hypertension secondary to endocrine disorders	0.000	0.856	0.143
I15.1 Hypertension secondary to other renal disorders	0.000	0.862	0.138
S72.0 Fracture of neck of femur	0.135	0.865	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.883	0.117
I12 Hypertensive renal disease	0.000	0.888	0.112
S72.01 Fracture of neck of femur (open)	0.097	0.903	0.000
N10 Acute tubulo-interstitial nephritis	0.000	0.924	0.076
I12.9 Hypertensive renal disease without renal failure	0.000	0.933	0.067
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.043	0.957	0.000
E20-E35 Disorders of other endocrine glands	0.043	0.957	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.042	0.958	0.000
E21.3 Hyperparathyroidism, unspecified	0.042	0.958	0.000
E23 Hypofunction and other disorders of pituitary gland	0.039	0.961	0.000
E27 Other disorders of adrenal gland	0.037	0.963	0.000
E34 Other endocrine disorders	0.037	0.963	0.000
E29 Testicular dysfunction	0.036	0.963	0.000
E22 Hyperfunction of pituitary gland	0.036	0.964	0.000
E23.0 Hypopituitarism	0.036	0.964	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.036	0.964	0.000
E28 Ovarian dysfunction	0.035	0.965	0.000
E28.3 Primary ovarian failure	0.034	0.966	0.000
E21.2 Other hyperparathyroidism	0.034	0.966	0.000
E31 Polyglandular dysfunction	0.034	0.966	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.033	0.967	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.033	0.967	0.000
E27.1 Primary adrenocortical insufficiency	0.033	0.967	0.000
E34.0 Carcinoid syndrome	0.032	0.968	0.000
E23.7 Disorder of pituitary gland, unspecified	0.032	0.968	0.000
E27.2 Addisonian crisis	0.031	0.969	0.000
E29.1 Testicular hypofunction	0.031	0.969	0.000
E25 Adrenogenital disorders	0.031	0.969	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.031	0.969	0.000
E32 Diseases of thymus	0.031	0.969	0.000
E30 Disorders of puberty, not elsewhere classified	0.031	0.969	0.000
E21.4 Other specified disorders of parathyroid gland	0.030	0.969	0.000
E20 Hypoparathyroidism	0.030	0.970	0.000
E34.9 Endocrine disorder, unspecified	0.030	0.970	0.000
E26 Hyperaldosteronism	0.030	0.970	0.000
E23.2 Diabetes insipidus	0.028	0.972	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.028	0.972	0.000
E23.1 Drug-induced hypopituitarism	0.028	0.972	0.000
E29.9 Testicular dysfunction, unspecified	0.028	0.972	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.028	0.972	0.000
E31.0 Autoimmune polyglandular failure	0.027	0.973	0.000
E23.6 Other disorders of pituitary gland	0.027	0.973	0.000
E27.5 Adrenomedullary hyperfunction	0.027	0.973	0.000
E27.0 Other adrenocortical overactivity	0.027	0.973	0.000
E34.5 Androgen resistance syndrome	0.027	0.973	0.000
E34.4 Constitutional tall stature	0.027	0.973	0.000
E34.3 Short stature, not elsewhere classified	0.027	0.973	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.027	0.973	0.000
E34.1 Other hypersecretion of intestinal hormones	0.027	0.973	0.000
E29.8 Other testicular dysfunction	0.026	0.974	0.000
E29.0 Testicular hyperfunction	0.026	0.974	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.026	0.974	0.000
E22.8 Other hyperfunction of pituitary gland	0.026	0.974	0.000
E28.9 Ovarian dysfunction, unspecified	0.025	0.974	0.000
E28.8 Other ovarian dysfunction	0.025	0.974	0.000
E28.1 Androgen excess	0.025	0.974	0.000
E28.0 Oestrogen excess	0.025	0.974	0.000
E31.9 Polyglandular dysfunction, unspecified	0.024	0.976	0.000
E31.8 Other polyglandular dysfunction	0.024	0.976	0.000
E31.1 Polyglandular hyperfunction	0.024	0.976	0.000
E27.9 Disorder of adrenal gland, unspecified	0.024	0.976	0.000
E34.8 Other specified endocrine disorders	0.023	0.977	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.023	0.977	0.000
E24 Cushing's syndrome	0.023	0.977	0.000
E25.9 Adrenogenital disorder, unspecified	0.022	0.977	0.000
E25.8 Other adrenogenital disorders	0.022	0.977	0.000
E21.0 Primary hyperparathyroidism	0.022	0.977	0.000
E30.9 Disorder of puberty, unspecified	0.022	0.978	0.000
E30.8 Other disorders of puberty	0.022	0.978	0.000
E30.1 Precocious puberty	0.022	0.978	0.000
E30.0 Delayed puberty	0.022	0.978	0.000
E32.9 Disease of thymus, unspecified	0.022	0.978	0.000
E32.8 Other diseases of thymus	0.022	0.978	0.000
E32.1 Abscess of thymus	0.022	0.978	0.000
E32.0 Persistent hyperplasia of thymus	0.022	0.978	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.022	0.978	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.022	0.978	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.022	0.978	0.000
E20.8 Other hypoparathyroidism	0.022	0.978	0.000
E20.1 Pseudohypoparathyroidism	0.022	0.978	0.000
E20.0 Idiopathic hypoparathyroidism	0.022	0.978	0.000
E26.9 Hyperaldosteronism, unspecified	0.021	0.978	0.000
E26.8 Other hyperaldosteronism	0.021	0.978	0.000
E26.1 Secondary hyperaldosteronism	0.021	0.978	0.000
E20.9 Hypoparathyroidism, unspecified	0.021	0.978	0.000
E22.1 Hyperprolactinaemia	0.021	0.979	0.000
E26.0 Primary hyperaldosteronism	0.020	0.980	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.019	0.981	0.000
E27.8 Other specified disorders of adrenal gland	0.018	0.981	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.018	0.982	0.000
E22.0 Acromegaly and pituitary gigantism	0.018	0.982	0.000
H50.1 Divergent concomitant strabismus	0.000	0.982	0.018
E27.4 Other and unspecified adrenocortical insufficiency	0.017	0.983	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.016	0.983	0.000
E24.3 Ectopic ACTH syndrome	0.016	0.983	0.000
E24.1 Nelson's syndrome	0.016	0.983	0.000
E24.9 Cushing's syndrome, unspecified	0.016	0.983	0.000
E24.8 Other Cushing's syndrome	0.016	0.984	0.000
S72 Fracture of femur	0.015	0.985	0.000
E24.0 Pituitary-dependent Cushing's disease	0.014	0.986	0.000
H50 Other strabismus	0.000	0.987	0.013
E24.2 Drug-induced Cushing's syndrome	0.013	0.987	0.000
H50.0 Convergent concomitant strabismus	0.000	0.987	0.013
S72.2 Subtrochanteric fracture	0.012	0.988	0.000
H50.2 Vertical strabismus	0.000	0.989	0.011
S72.7 Multiple fractures of femur	0.011	0.989	0.000
H50.4 Other and unspecified heterotropia	0.000	0.989	0.011
H44.2 Degenerative myopia	0.011	0.989	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.989	0.011
H50.8 Other specified strabismus	0.000	0.989	0.011
K70.3 Alcoholic cirrhosis of liver	0.000	0.989	0.011
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.990	0.010
M81.9 Osteoporosis, unspecified	0.010	0.990	0.000
H44 Disorders of globe	0.010	0.990	0.000
H50.3 Intermittent heterotropia	0.000	0.990	0.010
H50.6 Mechanical strabismus	0.000	0.990	0.010
S72.9 Fracture of femur, part unspecified	0.009	0.990	0.001
K70 Alcoholic liver disease	0.000	0.990	0.010
M81.98 Osteoporosis, unspecified (Other)	0.009	0.991	0.000
O14.1 Severe preeclampsia	0.000	0.991	0.009
S72.20 Subtrochanteric fracture (closed)	0.009	0.991	0.000
S72.3 Fracture of shaft of femur	0.008	0.991	0.001
H50.5 Heterophoria	0.000	0.991	0.009
H44.4 Hypotony of eye	0.009	0.991	0.000
S72.4 Fracture of lower end of femur	0.009	0.991	0.000
S72.8 Fractures of other parts of femur	0.008	0.991	0.001
S72.21 Subtrochanteric fracture (open)	0.008	0.991	0.000
H44.8 Other disorders of globe	0.009	0.991	0.000
H44.0 Purulent endophthalmitis	0.008	0.992	0.000
S72.71 Multiple fractures of femur (open)	0.008	0.992	0.000
S72.70 Multiple fractures of femur (closed)	0.008	0.992	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.008	0.992	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.992	0.008
M81.91 Osteoporosis, unspecified (Shoulder region)	0.008	0.992	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.008	0.992	0.000
S72.1 Pertrochanteric fracture	0.008	0.992	0.000
K70.0 Alcoholic fatty liver	0.000	0.992	0.008
M81.94 Osteoporosis, unspecified (Hand)	0.008	0.992	0.000
E28.2 Polycystic ovarian syndrome	0.007	0.992	0.001
K70.1 Alcoholic hepatitis	0.000	0.992	0.008
H44.1 Other endophthalmitis	0.008	0.992	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.992	0.008
M81.92 Osteoporosis, unspecified (Upper arm)	0.008	0.992	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.008	0.992	0.000
H44.9 Disorder of globe, unspecified	0.007	0.992	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.992	0.007
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.993	0.007
K76.6 Portal hypertension	0.000	0.993	0.007
H44.6 Retained (old) intraocular foreign body, magnetic	0.007	0.993	0.000
H44.3 Other degenerative disorders of globe	0.007	0.993	0.000
S72.31 Fracture of shaft of femur (open)	0.007	0.993	0.001
S72.91 Fracture of femur, part unspecified (open)	0.007	0.993	0.001
H44.5 Degenerated conditions of globe	0.007	0.993	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.993	0.007
M81.93 Osteoporosis, unspecified (Forearm)	0.007	0.993	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.007	0.993	0.000
Q05.9 Spina bifida, unspecified	0.007	0.993	0.000
O14.0 Moderate preeclampsia	0.000	0.993	0.007
S72.81 Fractures of other parts of femur (open)	0.006	0.993	0.001
K20 Oesophagitis	0.007	0.993	0.000
N10-N16 Renal tubulo-interstitial diseases	0.000	0.993	0.007
O47 False labour	0.006	0.994	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.006	0.994	0.000
S72.41 Fracture of lower end of femur (open)	0.006	0.994	0.000
M81 Osteoporosis without pathological fracture	0.006	0.994	0.000
S72.11 Pertrochanteric fracture (open)	0.006	0.994	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.005	0.994	0.001
B02.9 Zoster without complication	0.006	0.994	0.000
O14.2 HELLP syndrome	0.000	0.994	0.006
H72.0 Central perforation of tympanic membrane	0.000	0.995	0.005
M81.0 Postmenopausal osteoporosis	0.005	0.995	0.000
S72.40 Fracture of lower end of femur (closed)	0.005	0.995	0.000
K70.4 Alcoholic hepatic failure	0.000	0.995	0.005
M81.8 Other osteoporosis	0.005	0.995	0.000
O14.9 Preeclampsia, unspecified	0.000	0.995	0.005
K11.5 Sialolithiasis	0.005	0.995	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.000	0.995	0.005
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.995	0.005
O12.0 Gestational oedema	0.000	0.995	0.005
O47.0 False labour before 37 completed weeks of gestation	0.005	0.995	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.995	0.005
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.995	0.005
N15 Other renal tubulo-interstitial diseases	0.000	0.995	0.005
M81.6 Localised osteoporosis [Lequesne]	0.005	0.995	0.000
M81.5 Idiopathic osteoporosis	0.005	0.995	0.000
M81.1 Postoophorectomy osteoporosis	0.005	0.995	0.000
M81.80 Other osteoporosis (Multiple sites)	0.004	0.995	0.000
S72.80 Fractures of other parts of femur (closed)	0.003	0.995	0.002
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.004	0.996	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.004	0.996	0.000
M81.2 Osteoporosis of disuse	0.004	0.996	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.004	0.996	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.996	0.004
M81.4 Drug-induced osteoporosis	0.004	0.996	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.004	0.996	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.996	0.004
O00.9 Ectopic pregnancy, unspecified	0.000	0.996	0.004
H93.1 Tinnitus	0.000	0.996	0.004
M81.08 Postmenopausal osteoporosis (Other)	0.004	0.996	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.004	0.996	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.004	0.996	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.004	0.996	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.004	0.996	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.004	0.996	0.000
M81.89 Other osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.88 Other osteoporosis (Other)	0.004	0.996	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.86 Other osteoporosis (Lower leg)	0.004	0.996	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.84 Other osteoporosis (Hand)	0.004	0.996	0.000
M81.83 Other osteoporosis (Forearm)	0.004	0.996	0.000
M81.82 Other osteoporosis (Upper arm)	0.004	0.996	0.000
M81.81 Other osteoporosis (Shoulder region)	0.004	0.996	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.000	0.996	0.004
O12.1 Gestational proteinuria	0.000	0.996	0.004
O12.2 Gestational oedema with proteinuria	0.000	0.996	0.004
O15 Eclampsia	0.000	0.996	0.004
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.000	0.996	0.004
B18.2 Chronic viral hepatitis C	0.004	0.996	0.000
Z83.5 Family history of eye and ear disorders	0.004	0.996	0.000
B02 Zoster [herpes zoster]	0.004	0.996	0.000
S60.9 Superficial injury of wrist and hand, unspecified	0.004	0.996	0.000
H50.9 Strabismus, unspecified	0.000	0.996	0.004
S70-S79 Injuries to the hip and thigh	0.004	0.996	0.000
M06.4 Inflammatory polyarthropathy	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.000	0.996	0.004
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.004	0.996	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.996	0.004
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.996	0.004
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.996	0.004
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.996	0.004
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.996	0.004
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.996	0.004
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.996	0.004
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.996	0.003
N14.3 Nephropathy induced by heavy metals	0.000	0.996	0.003
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.996	0.003
N14.0 Analgesic nephropathy	0.000	0.996	0.003
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.996	0.004
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
I98.0 Cardiovascular syphilis	0.000	0.996	0.004
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.996	0.003
N15.0 Balkan nephropathy	0.000	0.996	0.003
Q05 Spina bifida	0.004	0.996	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.003	0.996	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.003	0.996	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.003	0.996	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.003	0.996	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.003	0.996	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.003	0.996	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.003	0.996	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.003	0.996	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.003	0.996	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.003	0.996	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.003	0.996	0.000
M81.58 Idiopathic osteoporosis (Other)	0.003	0.996	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.003	0.996	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.003	0.996	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.003	0.996	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.003	0.996	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.003	0.996	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.003	0.996	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.003	0.996	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.003	0.996	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.003	0.996	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.003	0.996	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.003	0.996	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.003	0.996	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.003	0.996	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.003	0.996	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.003	0.996	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.003	0.996	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.003	0.996	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.003	0.996	0.000
B02.3 Zoster ocular disease	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O47.9 False labour, unspecified	0.004	0.996	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.996	0.003
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.997	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.997	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.997	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.997	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.997	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.997	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.997	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.997	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.997	0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.003	0.997	0.000
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
H51 Other disorders of binocular movement	0.000	0.997	0.003
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.000	0.997	0.003
N15.1 Renal and perinephric abscess	0.000	0.997	0.003
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.000	0.997	0.003
S72.30 Fracture of shaft of femur (closed)	0.002	0.997	0.002
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.000	0.997	0.003
N11.1 Chronic obstructive pyelonephritis	0.000	0.997	0.003
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.000	0.997	0.003
H49 Paralytic strabismus	0.000	0.997	0.003
S75 Injury of blood vessels at hip and thigh level	0.003	0.997	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
H49.1 Fourth [trochlear] nerve palsy	0.000	0.997	0.003
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.003	0.997	0.000
F40.2 Specific (isolated) phobias	0.003	0.997	0.000
O15.9 Eclampsia, unspecified as to time period	0.000	0.997	0.003
O15.2 Eclampsia in the puerperium	0.000	0.997	0.003
O15.1 Eclampsia in labour	0.000	0.997	0.003
O15.0 Eclampsia in pregnancy	0.000	0.997	0.003
B02.8 Zoster with other complications	0.003	0.997	0.000
B02.7 Disseminated zoster	0.003	0.997	0.000
B02.1 Zoster meningitis	0.003	0.997	0.000
B02.0 Zoster encephalitis	0.003	0.997	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.003	0.997	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.003	0.997	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.003	0.997	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.003	0.997	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.003	0.997	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.003	0.997	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.003	0.997	0.000
S78 Traumatic amputation of hip and thigh	0.003	0.997	0.000
S77 Crushing injury of hip and thigh	0.003	0.997	0.000
S74 Injury of nerves at hip and thigh level	0.003	0.997	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.003	0.997	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.997	0.003
Q05.8 Sacral spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.003	0.997	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.003	0.997	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.003	0.997	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.002	0.997	0.000
L91.0 Keloid scar	0.000	0.997	0.003
H51.2 Internuclear ophthalmoplegia	0.000	0.997	0.003
S79.9 Unspecified injury of hip and thigh	0.003	0.997	0.000
S71 Open wound of hip and thigh	0.002	0.997	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.997	0.000
B01.8 Varicella with other complications	0.003	0.997	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.000	0.997	0.003
Q76.0 Spina bifida occulta	0.003	0.997	0.000
M50.0 Cervical disk disorder with myelopathy	0.003	0.997	0.000
S75.0 Injury of femoral artery	0.002	0.997	0.000
H51.9 Disorder of binocular movement, unspecified	0.000	0.997	0.002
H51.8 Other specified disorders of binocular movement	0.000	0.997	0.002
H51.1 Convergence insufficiency and excess	0.000	0.997	0.002
H51.0 Palsy of conjugate gaze	0.000	0.997	0.002
B01 Varicella [chickenpox]	0.003	0.997	0.000
B01.2 Varicella pneumonia	0.003	0.997	0.000
K41 Femoral hernia	0.003	0.997	0.000
B02.2 Zoster with other nervous system involvement	0.002	0.997	0.000
H49.8 Other paralytic strabismus	0.000	0.997	0.002
H49.4 Progressive external ophthalmoplegia	0.000	0.997	0.002
H49.3 Total (external) ophthalmoplegia	0.000	0.997	0.002
H49.0 Third [oculomotor] nerve palsy	0.000	0.997	0.002
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.002	0.997	0.000
S75.8 Injury of other blood vessels at hip and thigh level	0.002	0.997	0.000
S75.7 Injury of multiple blood vessels at hip and thigh level	0.002	0.997	0.000
S75.2 Injury of greater saphenous vein at hip and thigh level	0.002	0.997	0.000
S75.1 Injury of femoral vein at hip and thigh level	0.002	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
S79.7 Multiple injuries of hip and thigh	0.002	0.997	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.997	0.003
M95.0 Acquired deformity of nose	0.000	0.997	0.002
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
S71.0 Open wound of hip	0.002	0.998	0.000
S74.9 Injury of unspecified nerve at hip and thigh level	0.002	0.998	0.000
S74.8 Injury of other nerves at hip and thigh level	0.002	0.998	0.000
S74.7 Injury of multiple nerves at hip and thigh level	0.002	0.998	0.000
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.002	0.998	0.000
S74.1 Injury of femoral nerve at hip and thigh level	0.002	0.998	0.000
S74.0 Injury of sciatic nerve at hip and thigh level	0.002	0.998	0.000
S77.2 Crushing injury of hip with thigh	0.002	0.998	0.000
S77.1 Crushing injury of thigh	0.002	0.998	0.000
S77.0 Crushing injury of hip	0.002	0.998	0.000
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.002	0.998	0.000
S78.1 Traumatic amputation at level between hip and knee	0.002	0.998	0.000
S78.0 Traumatic amputation at hip joint	0.002	0.998	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.998	0.002
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.002	0.998	0.000
S76.1 Injury of quadriceps muscle and tendon	0.002	0.998	0.000
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.002	0.998	0.000
S76.2 Injury of adductor muscle and tendon of thigh	0.002	0.998	0.000
S76.0 Injury of muscle and tendon of hip	0.002	0.998	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.002	0.998	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.002	0.998	0.000
O21.9 Vomiting of pregnancy, unspecified	0.000	0.998	0.002
B01.9 Varicella without complications	0.002	0.998	0.000
T90.5 Sequelae of intracranial injury	0.000	0.998	0.002
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
S79.8 Other specified injuries of hip and thigh	0.002	0.998	0.000
T87.6 Other and unspecified complications of amputation stump	0.002	0.998	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.000	0.998	0.002
S00.1 Contusion of eyelid and periocular area	0.002	0.998	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.002	0.998	0.000
S71.7 Multiple open wounds of of hip and thigh	0.002	0.998	0.000
S70.7 Multiple superficial injuries of hip and thigh	0.002	0.998	0.000
K00.6 Disturbances in tooth eruption	0.002	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
B01.1 Varicella encephalitis	0.002	0.998	0.000
B01.0 Varicella meningitis	0.002	0.998	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.002	0.998	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.002	0.998	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.002	0.998	0.000
B18 Chronic viral hepatitis	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
H43-H45 Disorders of vitreous body and globe	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
S70.8 Other superficial injuries of hip and thigh	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.002	0.998	0.000
K51.4 Pseudopolyposis of colon	0.002	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.002	0.998	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.998	0.002
O00 Ectopic pregnancy	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.002	0.998	0.000
S70.1 Contusion of thigh	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.002	0.998	0.000
E46 Unspecified protein-energy malnutrition	0.002	0.998	0.000
M25.31 Other instability of joint (Shoulder region)	0.000	0.998	0.002
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.998	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.998	0.000
Q76.7 Congenital malformation of sternum	0.002	0.998	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.998	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.998	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.998	0.002
S70.9 Superficial injury of hip and thigh, unspecified	0.002	0.998	0.000
H72.1 Attic perforation of tympanic membrane	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
B91 Sequelae of poliomyelitis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations