TreeWAS – Variant ID: rs2071800

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	1.000	0.000	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	1.000	0.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000	0.000
J45.9 Asthma, unspecified	1.000	0.000	0.000
K90.0 Coeliac disease	0.000	0.000	1.000
M05.9 Seropositive rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06.9 Rheumatoid arthritis, unspecified	1.000	0.000	0.000
M06 Other rheumatoid arthritis	1.000	0.000	0.000
M05-M14 Inflammatory polyarthropathies	1.000	0.000	0.000
M05 Seropositive rheumatoid arthritis	1.000	0.000	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.999	0.001	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.996	0.004	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.971	0.029	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.954	0.046	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.952	0.048	0.000
M06.3 Rheumatoid nodule	0.950	0.050	0.000
M06.0 Seronegative rheumatoid arthritis	0.940	0.060	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.918	0.082	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.906	0.094	0.000
M11 Other crystal arthropathies	0.899	0.101	0.000
M06.4 Inflammatory polyarthropathy	0.893	0.107	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.880	0.120	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.880	0.120	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.861	0.139	0.000
M06.34 Rheumatoid nodule (Hand)	0.860	0.140	0.000
M20-M25 Other joint disorders	0.857	0.143	0.000
M45-M49 Spondylopathies	0.852	0.148	0.000
M20 Acquired deformities of fingers and toes	0.851	0.149	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.850	0.150	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.848	0.152	0.000
M48 Other spondylopathies	0.843	0.157	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.839	0.161	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.835	0.165	0.000
M20.4 Other hammer toe(s) (acquired)	0.833	0.167	0.000
M11.2 Other chondrocalcinosis	0.827	0.173	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.825	0.175	0.000
M48.0 Spinal stenosis	0.821	0.179	0.000
M05.8 Other seropositive rheumatoid arthritis	0.814	0.186	0.000
M48.06 Spinal stenosis (Lumbar region)	0.812	0.188	0.000
M40-M43 Deforming dorsopathies	0.792	0.208	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.790	0.210	0.000
M06.98 Rheumatoid arthritis, unspecified (Other)	0.784	0.216	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.784	0.216	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.775	0.225	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.773	0.227	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.768	0.232	0.000
M65-M68 Disorders of synovium and tendon	0.761	0.239	0.000
M35 Other systemic involvement of connective tissue	0.755	0.245	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.753	0.247	0.000
M86-M90 Other osteopathies	0.733	0.266	0.000
M20.3 Other deformity of hallux (acquired)	0.728	0.272	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.718	0.282	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.717	0.283	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.717	0.283	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.717	0.283	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.717	0.283	0.000
M06.8 Other specified rheumatoid arthritis	0.717	0.283	0.000
M06.2 Rheumatoid bursitis	0.717	0.283	0.000
M06.1 Adult-onset Still's disease	0.717	0.283	0.000
M12 Other specific arthropathies	0.717	0.283	0.000
M09 Juvenile arthritis in diseases classified elsewhere	0.717	0.283	0.000
M08 Juvenile arthritis	0.717	0.283	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.717	0.283	0.000
M05.2 Rheumatoid vasculitis	0.717	0.283	0.000
M05.1 Rheumatoid lung disease	0.717	0.283	0.000
M05.0 Felty's syndrome	0.717	0.283	0.000
M35.3 Polymyalgia rheumatica	0.716	0.284	0.000
M14 Arthropathies in other diseases classified elsewhere	0.709	0.291	0.000
M31 Other necrotising vasculopathies	0.706	0.294	0.000
E03 Other hypothyroidism	0.703	0.297	0.000
M41 Scoliosis	0.696	0.304	0.000
M22 Disorders of patella	0.682	0.318	0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.681	0.318	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.681	0.319	0.000
M06.38 Rheumatoid nodule (Other)	0.681	0.319	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.681	0.319	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.681	0.319	0.000
M06.33 Rheumatoid nodule (Forearm)	0.681	0.319	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.681	0.319	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.681	0.319	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.680	0.320	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.674	0.326	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.674	0.326	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.674	0.326	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.674	0.326	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.674	0.326	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.674	0.326	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.674	0.326	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.674	0.326	0.000
M10 Gout	0.665	0.335	0.000
M60-M63 Disorders of muscles	0.662	0.338	0.000
M91-M94 Chondropathies	0.656	0.343	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.653	0.347	0.000
M50-M54 Other dorsopathies	0.650	0.350	0.000
M11.9 Crystal arthropathy, unspecified	0.645	0.355	0.000
M11.8 Other specified crystal arthropathies	0.645	0.355	0.000
M11.1 Familial chondrocalcinosis	0.645	0.355	0.000
M11.0 Hydroxyapatite deposition disease	0.645	0.355	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.641	0.359	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.641	0.359	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.641	0.359	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.641	0.359	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.641	0.359	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.641	0.359	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.641	0.359	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.641	0.359	0.000
M30 Polyarteritis nodosa and related conditions	0.640	0.360	0.000
M00-M03 Infectious arthropathies	0.638	0.362	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.637	0.363	0.000
M20.1 Hallux valgus (acquired)	0.632	0.368	0.000
M48.02 Spinal stenosis (Cervical region)	0.629	0.371	0.000
M41.9 Scoliosis, unspecified	0.627	0.373	0.000
M33 Dermatopolymyositis	0.625	0.375	0.000
M46 Other inflammatory spondylopathies	0.622	0.378	0.000
M35.1 Other overlap syndromes	0.621	0.379	0.000
J45 Asthma	0.616	0.384	0.000
M67 Other disorders of synovium and tendon	0.615	0.385	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.615	0.385	0.000
M32 Systemic lupus erythematosus	0.615	0.385	0.000
M49 Spondylopathies in diseases classified elsewhere	0.609	0.391	0.000
M51 Other intervertebral disk disorders	0.609	0.391	0.000
M48.9 Spondylopathy, unspecified	0.605	0.395	0.000
M48.8 Other specified spondylopathies	0.605	0.395	0.000
M48.4 Fatigue fracture of vertebra	0.605	0.395	0.000
M48.3 Traumatic spondylopathy	0.605	0.395	0.000
M48.2 Kissing spine	0.605	0.395	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.605	0.395	0.000
M43 Other deforming dorsopathies	0.601	0.399	0.000
M07 Psoriatic and enteropathic arthropathies	0.596	0.403	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.593	0.407	0.000
M11.28 Other chondrocalcinosis (Other)	0.593	0.407	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.593	0.407	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.593	0.407	0.000
M11.24 Other chondrocalcinosis (Hand)	0.593	0.407	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.593	0.407	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.593	0.407	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.593	0.407	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.593	0.407	0.000
M86 Osteomyelitis	0.592	0.408	0.000
M65 Synovitis and tenosynovitis	0.592	0.408	0.000
M31.6 Other giant cell arteritis	0.591	0.409	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.588	0.412	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.588	0.412	0.000
M48.04 Spinal stenosis (Thoracic region)	0.588	0.412	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.588	0.412	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.588	0.412	0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.584	0.416	0.000
M05.88 Other seropositive rheumatoid arthritis (Other)	0.584	0.416	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.584	0.416	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.584	0.416	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.584	0.416	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.584	0.416	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.584	0.416	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.584	0.416	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.584	0.416	0.000
M66 Spontaneous rupture of synovium and tendon	0.568	0.432	0.000
M42 Spinal osteochondrosis	0.567	0.432	0.000
M40 Kyphosis and lordosis	0.567	0.432	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.567	0.433	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.554	0.446	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.554	0.446	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.554	0.446	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.554	0.446	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.554	0.446	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.554	0.446	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.554	0.446	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.554	0.446	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.552	0.448	0.000
M22.2 Patellofemoral disorders	0.551	0.449	0.000
M89 Other disorders of bone	0.546	0.454	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.546	0.454	0.000
M21 Other acquired deformities of limbs	0.542	0.457	0.000
M88 Paget's disease of bone [osteitis deformans]	0.542	0.458	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.542	0.458	0.000
M35.8 Other specified systemic involvement of connective tissue	0.542	0.458	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.542	0.458	0.000
M35.5 Multifocal fibrosclerosis	0.542	0.458	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.542	0.458	0.000
M35.2 Behcet's disease	0.542	0.458	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.538	0.462	0.000
M51.2 Other specified intervertebral disk displacement	0.534	0.466	0.000
M90 Osteopathies in diseases classified elsewhere	0.530	0.469	0.000
M31.3 Wegener's granulomatosis	0.529	0.470	0.000
M22.3 Other derangements of patella	0.524	0.476	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.521	0.479	0.000
E03.8 Other specified hypothyroidism	0.515	0.485	0.000
M51.9 Intervertebral disk disorder, unspecified	0.515	0.485	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.514	0.486	0.000
M06.18 Adult-onset Still's disease (Other)	0.514	0.486	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.514	0.486	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.514	0.486	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.514	0.486	0.000
M06.14 Adult-onset Still's disease (Hand)	0.514	0.486	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.514	0.486	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.514	0.486	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.514	0.486	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.514	0.486	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.514	0.486	0.000
M06.28 Rheumatoid bursitis (Other)	0.514	0.486	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.514	0.486	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.514	0.486	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.514	0.486	0.000
M06.24 Rheumatoid bursitis (Hand)	0.514	0.486	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.514	0.486	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.514	0.486	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.514	0.486	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.514	0.486	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.514	0.486	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.514	0.486	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.514	0.486	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.514	0.486	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.514	0.486	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.514	0.486	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.514	0.486	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.514	0.486	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.514	0.486	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.514	0.486	0.000
M08.9 Juvenile arthritis, unspecified	0.514	0.486	0.000
M08.8 Other juvenile arthritis	0.514	0.486	0.000
M08.4 Pauciarticular juvenile arthritis	0.514	0.486	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.514	0.486	0.000
M08.2 Juvenile arthritis with systemic onset	0.514	0.486	0.000
M08.1 Juvenile ankylosing spondylitis	0.514	0.486	0.000
M08.0 Juvenile rheumatoid arthritis	0.514	0.486	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.514	0.486	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.514	0.486	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.514	0.486	0.000
M09.0 Juvenile arthritis in psoriasis	0.514	0.486	0.000
M12.8 Other specific arthropathies, not elsewhere classified	0.514	0.486	0.000
M12.5 Traumatic arthropathy	0.514	0.486	0.000
M12.4 Intermittent hydrarthrosis	0.514	0.486	0.000
M12.3 Palindromic rheumatism	0.514	0.486	0.000
M12.2 Villonodular synovitis (pigmented)	0.514	0.486	0.000
M12.1 Kaschin-Beck disease	0.514	0.486	0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]	0.514	0.486	0.000
M05.09 Felty's syndrome (Site unspecified)	0.514	0.486	0.000
M05.08 Felty's syndrome (Other)	0.514	0.486	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.514	0.486	0.000
M05.06 Felty's syndrome (Lower leg)	0.514	0.486	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.514	0.486	0.000
M05.04 Felty's syndrome (Hand)	0.514	0.486	0.000
M05.03 Felty's syndrome (Forearm)	0.514	0.486	0.000
M05.02 Felty's syndrome (Upper arm)	0.514	0.486	0.000
M05.01 Felty's syndrome (Shoulder region)	0.514	0.486	0.000
M05.00 Felty's syndrome (Multiple sites)	0.514	0.486	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.514	0.486	0.000
M05.18 Rheumatoid lung disease (Other)	0.514	0.486	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.514	0.486	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.514	0.486	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.514	0.486	0.000
M05.14 Rheumatoid lung disease (Hand)	0.514	0.486	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.514	0.486	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.514	0.486	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.514	0.486	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.514	0.486	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.514	0.486	0.000
M05.28 Rheumatoid vasculitis (Other)	0.514	0.486	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.514	0.486	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.514	0.486	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.514	0.486	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.514	0.486	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.514	0.486	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.514	0.486	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.514	0.486	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.514	0.486	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.514	0.486	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.514	0.486	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.514	0.486	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.514	0.486	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.514	0.486	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.514	0.486	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.514	0.486	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.514	0.486	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.514	0.486	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.514	0.486	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.512	0.488	0.000
M87 Osteonecrosis	0.510	0.490	0.000
M24 Other specific joint derangements	0.509	0.491	0.000
M94 Other disorders of cartilage	0.509	0.491	0.000
M60 Myositis	0.508	0.492	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.508	0.492	0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders	0.508	0.492	0.000
M14.4 Arthropathy in amyloidosis	0.508	0.492	0.000
M14.3 Lipoid dermatoarthritis	0.508	0.492	0.000
M14.2 Diabetic arthropathy	0.508	0.492	0.000
M14.1 Crystal arthropathy in other metabolic disorders	0.508	0.492	0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders	0.508	0.492	0.000
M31.9 Necrotising vasculopathy, unspecified	0.506	0.494	0.000
M31.8 Other specified necrotising vasculopathies	0.506	0.494	0.000
M31.7 Microscopic polyangiitis	0.506	0.494	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.506	0.494	0.000
M31.2 Lethal midline granuloma	0.506	0.494	0.000
M31.1 Thrombotic microangiopathy	0.506	0.494	0.000
M31.0 Hypersensitivity angiitis	0.506	0.494	0.000
E03.5 Myxoedema coma	0.504	0.496	0.000
E03.4 Atrophy of thyroid (acquired)	0.504	0.496	0.000
E03.3 Postinfectious hypothyroidism	0.504	0.496	0.000
E03.1 Congenital hypothyroidism without goitre	0.504	0.496	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.504	0.496	0.000
M51.8 Other specified intervertebral disk disorders	0.502	0.498	0.000
J45.0 Predominantly allergic asthma	0.502	0.498	0.000
M43.1 Spondylolisthesis	0.501	0.498	0.000
M99 Biomechanical lesions, not elsewhere classified	0.500	0.500	0.000
M48.09 Spinal stenosis (Site unspecified)	0.500	0.500	0.000
M14.6 Neuropathic arthropathy	0.500	0.500	0.000
M41.8 Other forms of scoliosis	0.499	0.501	0.000
M41.5 Other secondary scoliosis	0.499	0.501	0.000
M41.4 Neuromuscular scoliosis	0.499	0.501	0.000
M41.3 Thoracogenic scoliosis	0.499	0.501	0.000
M41.2 Other idiopathic scoliosis	0.499	0.501	0.000
M41.1 Juvenile idiopathic scoliosis	0.499	0.501	0.000
M41.0 Infantile idiopathic scoliosis	0.499	0.501	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.494	0.506	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.493	0.507	0.000
M22.4 Chondromalacia patellae	0.490	0.510	0.000
M22.1 Recurrent subluxation of patella	0.489	0.511	0.000
M22.9 Disorder of patella, unspecified	0.489	0.511	0.000
M22.0 Recurrent dislocation of patella	0.489	0.511	0.000
M86.9 Osteomyelitis, unspecified	0.488	0.512	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.484	0.516	0.000
M70-M79 Other soft tissue disorders	0.483	0.517	0.000
M67.8 Other specified disorders of synovium and tendon	0.480	0.519	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.478	0.522	0.000
M92 Other juvenile osteochondrosis	0.477	0.523	0.000
M10.4 Other secondary gout	0.477	0.523	0.000
M10.3 Gout due to impairment of renal function	0.477	0.523	0.000
M10.2 Drug-induced gout	0.477	0.523	0.000
M10.1 Lead-induced gout	0.477	0.523	0.000
M10.0 Idiopathic gout	0.477	0.523	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.475	0.525	0.000
M61 Calcification and ossification of muscle	0.475	0.525	0.000
M34 Systemic sclerosis	0.474	0.526	0.000
M91 Juvenile osteochondrosis of hip and pelvis	0.471	0.529	0.000
M35.7 Hypermobility syndrome	0.467	0.533	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.467	0.533	0.000
M46.4 Discitis, unspecified	0.466	0.534	0.000
M45 Ankylosing spondylitis	0.463	0.537	0.000
M11.09 Hydroxyapatite deposition disease (Site unspecified)	0.462	0.538	0.000
M11.08 Hydroxyapatite deposition disease (Other)	0.462	0.538	0.000
M11.07 Hydroxyapatite deposition disease (Ankle and foot)	0.462	0.538	0.000
M11.06 Hydroxyapatite deposition disease (Lower leg)	0.462	0.538	0.000
M11.05 Hydroxyapatite deposition disease (Pelvic region and thigh)	0.462	0.538	0.000
M11.04 Hydroxyapatite deposition disease (Hand)	0.462	0.538	0.000
M11.03 Hydroxyapatite deposition disease (Forearm)	0.462	0.538	0.000
M11.02 Hydroxyapatite deposition disease (Upper arm)	0.462	0.538	0.000
M11.01 Hydroxyapatite deposition disease (Shoulder region)	0.462	0.538	0.000
M11.00 Hydroxyapatite deposition disease (Multiple sites)	0.462	0.538	0.000
M11.19 Familial chondrocalcinosis (Site unspecified)	0.462	0.538	0.000
M11.18 Familial chondrocalcinosis (Other)	0.462	0.538	0.000
M11.17 Familial chondrocalcinosis (Ankle and foot)	0.462	0.538	0.000
M11.16 Familial chondrocalcinosis (Lower leg)	0.462	0.538	0.000
M11.15 Familial chondrocalcinosis (Pelvic region and thigh)	0.462	0.538	0.000
M11.14 Familial chondrocalcinosis (Hand)	0.462	0.538	0.000
M11.13 Familial chondrocalcinosis (Forearm)	0.462	0.538	0.000
M11.12 Familial chondrocalcinosis (Upper arm)	0.462	0.538	0.000
M11.11 Familial chondrocalcinosis (Shoulder region)	0.462	0.538	0.000
M11.10 Familial chondrocalcinosis (Multiple sites)	0.462	0.538	0.000
M11.89 Other specified crystal arthropathies (Site unspecified)	0.462	0.538	0.000
M11.88 Other specified crystal arthropathies (Other)	0.462	0.538	0.000
M11.87 Other specified crystal arthropathies (Ankle and foot)	0.462	0.538	0.000
M11.86 Other specified crystal arthropathies (Lower leg)	0.462	0.538	0.000
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)	0.462	0.538	0.000
M11.84 Other specified crystal arthropathies (Hand)	0.462	0.538	0.000
M11.83 Other specified crystal arthropathies (Forearm)	0.462	0.538	0.000
M11.82 Other specified crystal arthropathies (Upper arm)	0.462	0.538	0.000
M11.81 Other specified crystal arthropathies (Shoulder region)	0.462	0.538	0.000
M11.80 Other specified crystal arthropathies (Multiple sites)	0.462	0.538	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.462	0.538	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.462	0.538	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.462	0.538	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.462	0.538	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.462	0.538	0.000
M11.94 Crystal arthropathy, unspecified (Hand)	0.462	0.538	0.000
M11.93 Crystal arthropathy, unspecified (Forearm)	0.462	0.538	0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.462	0.538	0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.462	0.538	0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.462	0.538	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.459	0.541	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.459	0.541	0.000
M30.2 Juvenile polyarteritis	0.459	0.541	0.000
M30.0 Polyarteritis nodosa	0.459	0.541	0.000
M33.1 Other dermatomyositis	0.459	0.541	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.457	0.543	0.000
M02 Reactive arthropathies	0.457	0.543	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.457	0.543	0.000
M22.8 Other disorders of patella	0.457	0.543	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.456	0.544	0.000
M67.1 Other contracture of tendon (sheath)	0.455	0.545	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.454	0.546	0.000
M20.0 Deformity of finger(s)	0.454	0.546	0.000
M89.0 Algoneurodystrophy	0.454	0.546	0.000
M53 Other dorsopathies, not elsewhere classified	0.452	0.547	0.000
M66.2 Spontaneous rupture of extensor tendons	0.451	0.549	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.449	0.550	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.449	0.550	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.449	0.550	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.449	0.550	0.000
M62 Other disorders of muscle	0.449	0.551	0.000
M33.9 Dermatopolymyositis, unspecified	0.448	0.552	0.000
M33.2 Polymyositis	0.448	0.552	0.000
M33.0 Juvenile dermatomyositis	0.448	0.552	0.000
M46.8 Other specified inflammatory spondylopathies	0.446	0.554	0.000
M46.5 Other infective spondylopathies	0.446	0.554	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.446	0.554	0.000
M46.2 Osteomyelitis of vertebra	0.446	0.554	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.446	0.554	0.000
M46.0 Spinal enthesopathy	0.446	0.554	0.000
M00 Pyogenic arthritis	0.445	0.554	0.000
J45.8 Mixed asthma	0.442	0.558	0.000
J45.1 Nonallergic asthma	0.442	0.558	0.000
M24.2 Disorder of ligament	0.442	0.558	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.441	0.559	0.000
M67.4 Ganglion	0.441	0.559	0.000
M67.3 Transient synovitis	0.441	0.559	0.000
M67.0 Short Achilles tendon (acquired)	0.441	0.559	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.441	0.559	0.000
M32.8 Other forms of systemic lupus erythematosus	0.441	0.559	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.441	0.559	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.441	0.559	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.441	0.559	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.441	0.559	0.000
M36.3 Arthropathy in other blood disorders	0.441	0.559	0.000
M36.2 Haemophilic arthropathy	0.441	0.559	0.000
M36.1 Arthropathy in neoplastic disease	0.441	0.559	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.441	0.559	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.439	0.561	0.000
M49.8 Spondylopathy in other diseases classified elsewhere	0.437	0.563	0.000
M49.4 Neuropathic spondylopathy	0.437	0.563	0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere	0.437	0.563	0.000
M49.2 Enterobacterial spondylitis	0.437	0.563	0.000
M49.1 Brucella spondylitis	0.437	0.563	0.000
M49.0 Tuberculosis of spine	0.437	0.563	0.000
M65.3 Trigger finger	0.437	0.563	0.000
M51.3 Other specified intervertebral disk degeneration	0.436	0.563	0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.436	0.563	0.000
M51.4 Schmorl's nodes	0.436	0.563	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.436	0.564	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.436	0.564	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.435	0.565	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.434	0.566	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.434	0.566	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.434	0.566	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.434	0.566	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.434	0.566	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.434	0.566	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.434	0.566	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.434	0.566	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.434	0.566	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.434	0.566	0.000
M48.29 Kissing spine (Site unspecified)	0.434	0.566	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.434	0.566	0.000
M48.27 Kissing spine (Lumbosacral region)	0.434	0.566	0.000
M48.26 Kissing spine (Lumbar region)	0.434	0.566	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.434	0.566	0.000
M48.24 Kissing spine (Thoracic region)	0.434	0.566	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.434	0.566	0.000
M48.22 Kissing spine (Cervical region)	0.434	0.566	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.434	0.566	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.434	0.566	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.434	0.566	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.434	0.566	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.434	0.566	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.434	0.566	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.434	0.566	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.434	0.566	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.434	0.566	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.434	0.566	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.434	0.566	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.434	0.566	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.434	0.566	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.434	0.566	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.434	0.566	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.434	0.566	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.434	0.566	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.434	0.566	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.434	0.566	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.434	0.566	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.434	0.566	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.434	0.566	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.434	0.566	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.434	0.566	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.434	0.566	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.434	0.566	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.434	0.566	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.434	0.566	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.434	0.566	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.434	0.566	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.434	0.566	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.434	0.566	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.434	0.566	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.434	0.566	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.434	0.566	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.434	0.566	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.434	0.566	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.434	0.566	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.434	0.566	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.434	0.566	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.434	0.566	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.434	0.566	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations