TreeWAS – Variant ID: rs2072209

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.039	0.961	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.037	0.963	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.037	0.963	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.032	0.968	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.031	0.969	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.028	0.972	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.026	0.973	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.024	0.976	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.020	0.980	0.000
M23 Internal derangement of knee	0.020	0.980	0.000
M23.4 Loose body in knee	0.017	0.982	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.017	0.983	0.000
M23.0 Cystic meniscus	0.017	0.983	0.000
M23.49 Loose body in knee-Unspec lig/men	0.016	0.984	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.985	0.015
T39.1 4-Aminophenol derivatives	0.000	0.985	0.015
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.985	0.015
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.015	0.985	0.000
M23.1 Discoid meniscus (congenital)	0.014	0.986	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.986	0.014
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.014	0.986	0.000
M23.3 Other meniscus derangements	0.014	0.986	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.014	0.986	0.000
M23.43 Loose body in knee-Med lig/oth men	0.013	0.986	0.000
M23.9 Internal derangement of knee, unspecified	0.013	0.987	0.000
T39.0 Salicylates	0.000	0.987	0.013
M23.47 Loose body in knee-Capsular lig	0.013	0.987	0.000
M23.46 Loose body in knee-O/unsp lat men	0.013	0.987	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.013	0.987	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.013	0.987	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.013	0.987	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.013	0.987	0.000
M23.40 Loose body in knee-Mult sites	0.013	0.987	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.987	0.013
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.013	0.987	0.000
M23.07 Cystic meniscus-Capsular lig	0.012	0.987	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.012	0.987	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.012	0.987	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.012	0.987	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.012	0.987	0.000
M23.00 Cystic meniscus (Multiple sites)	0.012	0.987	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.012	0.987	0.000
M23.5 Chronic instability of knee	0.012	0.987	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.012	0.988	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.988	0.012
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.988	0.012
M23.8 Other internal derangements of knee	0.011	0.989	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.989	0.011
T39.4 Antirheumatics, not elsewhere classified	0.000	0.989	0.011
T39.2 Pyrazolone derivatives	0.000	0.989	0.011
T43.2 Other and unspecified antidepressants	0.000	0.989	0.011
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.011	0.989	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.010	0.989	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.010	0.989	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.010	0.989	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.010	0.989	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.989	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.989	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.989	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.010	0.989	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.010	0.989	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.990	0.010
M23.37 Other meniscus derangements-Capsular lig	0.010	0.990	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.990	0.010
T40.4 Other synthetic narcotics	0.000	0.990	0.010
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.990	0.010
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.010	0.990	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.010	0.990	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.010	0.990	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.990	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.990	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.010	0.990	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.010	0.990	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.990	0.010
T40.2 Other opioids	0.000	0.990	0.010
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.990	0.010
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.990	0.010
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.991	0.009
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.991	0.009
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.991	0.009
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.991	0.009
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.991	0.009
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.991	0.009
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.009	0.991	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.009	0.991	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.009	0.991	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.009	0.991	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.009	0.991	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.009	0.991	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.009	0.991	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.009	0.991	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.991	0.009
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.009	0.991	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.009	0.991	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.009	0.991	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.009	0.991	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.009	0.991	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.009	0.991	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.009	0.991	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.009	0.991	0.000
T36 Poisoning by systemic antibiotics	0.000	0.991	0.009
T43.9 Psychotropic drug, unspecified	0.000	0.991	0.009
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.991	0.009
T43.6 Psychostimulants with abuse potential	0.000	0.991	0.009
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.991	0.009
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.991	0.009
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.991	0.008
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.991	0.008
T40.8 Lysergide [LSD]	0.000	0.991	0.008
T40.7 Cannabis (derivatives)	0.000	0.991	0.008
T40.5 Cocaine	0.000	0.991	0.008
T40.3 Methadone	0.000	0.991	0.008
T40.1 Heroin	0.000	0.991	0.008
T40.0 Opium	0.000	0.991	0.008
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.008	0.991	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.008	0.992	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.992	0.008
T40.6 Other and unspecified narcotics	0.000	0.992	0.008
M23.87 Other internal derangements of knee (Capsular ligament)	0.008	0.992	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.008	0.992	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.008	0.992	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.008	0.992	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.008	0.992	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.992	0.008
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.008	0.992	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.992	0.008
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.992	0.008
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.992	0.008
T42.3 Barbiturates	0.000	0.992	0.008
T42.2 Succinimides and oxazolidinediones	0.000	0.992	0.008
T42.0 Hydantoin derivatives	0.000	0.992	0.008
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.992	0.008
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.992	0.007
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.992	0.007
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.992	0.007
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.992	0.007
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.992	0.007
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.992	0.007
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.992	0.007
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.992	0.007
T44.0 Anticholinesterase agents	0.000	0.992	0.007
T42.1 Iminostilbenes	0.000	0.992	0.007
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.007	0.992	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.993	0.007
T45.0 Antiallergic and antiemetic drugs	0.000	0.993	0.007
Z45.8 Adjustment and management of other implanted devices	0.007	0.993	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.007	0.993	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.993	0.007
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.993	0.007
T47.7 Emetics	0.000	0.993	0.007
T47.6 Antidiarrhoeal drugs	0.000	0.993	0.007
T47.5 Digestants	0.000	0.993	0.007
T47.4 Other laxatives	0.000	0.993	0.007
T47.3 Saline and osmotic laxatives	0.000	0.993	0.007
T47.2 Stimulant laxatives	0.000	0.993	0.007
T47.0 Histamine H(2)-receptor antagonists	0.000	0.993	0.007
T42.4 Benzodiazepines	0.000	0.993	0.007
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.993	0.007
T45.8 Other primarily systemic and haematological agents	0.000	0.993	0.007
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.993	0.007
T45.6 Fibrinolysis-affecting drugs	0.000	0.993	0.007
T45.4 Iron and its compounds	0.000	0.993	0.007
T45.3 Enzymes, not elsewhere classified	0.000	0.993	0.007
T45.2 Vitamins, not elsewhere classified	0.000	0.993	0.007
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.993	0.007
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.993	0.007
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.993	0.007
T37.5 Antiviral drugs	0.000	0.993	0.007
T37.4 Anthelminthics	0.000	0.993	0.007
T37.3 Other antiprotozoal drugs	0.000	0.993	0.007
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.993	0.007
T37.1 Antimycobacterial drugs	0.000	0.993	0.007
T37.0 Sulphonamides	0.000	0.993	0.007
T41.5 Therapeutic gases	0.000	0.993	0.007
T41.4 Anaesthetic, unspecified	0.000	0.993	0.007
T41.3 Local anaesthetics	0.000	0.993	0.007
T41.2 Other and unspecified general anaesthetics	0.000	0.993	0.007
T41.1 Intravenous anaesthetics	0.000	0.993	0.007
T41.0 Inhaled anaesthetics	0.000	0.993	0.007
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.993	0.007
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.993	0.007
T48.5 Anti-common-cold drugs	0.000	0.993	0.007
T48.4 Expectorants	0.000	0.993	0.007
T48.3 Antitussives	0.000	0.993	0.007
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.993	0.007
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.993	0.007
T48.0 Oxytocic drugs	0.000	0.993	0.007
T49.9 Topical agent, unspecified	0.000	0.993	0.007
T49.8 Other topical agents	0.000	0.993	0.007
T49.7 Dental drugs, topically applied	0.000	0.993	0.007
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.993	0.007
T49.5 Ophthalmological drugs and preparations	0.000	0.993	0.007
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.993	0.007
T49.3 Emollients, demulcents and protectants	0.000	0.993	0.007
T49.2 Local astringents and local detergents	0.000	0.993	0.007
T49.1 Antipruritics	0.000	0.993	0.007
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.993	0.007
T45.5 Anticoagulants	0.000	0.993	0.007
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.006	0.993	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.006	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.993	0.007
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.993	0.007
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.993	0.007
T46.7 Peripheral vasodilators	0.000	0.993	0.007
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.993	0.007
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.993	0.007
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.993	0.007
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.993	0.007
T36.9 Systemic antibiotic, unspecified	0.000	0.993	0.006
T36.8 Other systemic antibiotics	0.000	0.993	0.006
T36.7 Antifungal antibiotics, systemically used	0.000	0.993	0.006
T36.6 Rifamycins	0.000	0.993	0.006
T36.5 Aminoglycosides	0.000	0.993	0.006
T36.4 Tetracyclines	0.000	0.993	0.006
T36.3 Macrolides	0.000	0.993	0.006
T36.2 Chloramphenicol group	0.000	0.993	0.006
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.993	0.006
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.993	0.006
T46.1 Calcium-channel blockers	0.000	0.993	0.006
T50.8 Diagnostic agents	0.000	0.994	0.006
T50.7 Analeptics and opioid receptor antagonists	0.000	0.994	0.006
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.994	0.006
T50.5 Appetite depressants	0.000	0.994	0.006
T50.4 Drugs affecting uric acid metabolism	0.000	0.994	0.006
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.994	0.006
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.994	0.006
T50.1 Loop [high-ceiling] diuretics	0.000	0.994	0.006
T50.0 Mineralocorticoids and their antagonists	0.000	0.994	0.006
S62.30 Fracture of other metacarpal bone (closed)	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.994	0.006
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.994	0.006
T38.7 Androgens and anabolic congeners	0.000	0.994	0.006
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.994	0.006
T38.5 Other oestrogens and progestogens	0.000	0.994	0.006
T38.4 Oral contraceptives	0.000	0.994	0.006
T38.2 Antithyroid drugs	0.000	0.994	0.006
T38.1 Thyroid hormones and substitutes	0.000	0.994	0.006
T38.0 Glucocorticoids and synthetic analogues	0.000	0.994	0.006
K51.9 Ulcerative colitis, unspecified	0.000	0.994	0.006
T36.0 Penicillins	0.000	0.994	0.006
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.005	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.994	0.005
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.005	0.994	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.000	0.995	0.005
Z53.9 Procedure not carried out, unspecified reason	0.005	0.995	0.000
G55.3 Nerve root and plexus compressions in other dorsopathies	0.000	0.995	0.005
K51 Ulcerative colitis	0.000	0.995	0.005
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.995	0.004
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.995	0.005
K51.2 Ulcerative (chronic) proctitis	0.000	0.995	0.005
S62.3 Fracture of other metacarpal bone	0.005	0.995	0.000
H18.5 Hereditary corneal dystrophies	0.005	0.995	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.000	0.996	0.004
H18.2 Other corneal oedema	0.004	0.996	0.000
K51.5 Mucosal proctocolitis	0.000	0.996	0.004
Y86 Sequelae of other accidents	0.000	0.996	0.004
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.996	0.004
K51.4 Pseudopolyposis of colon	0.000	0.996	0.004
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.996	0.004
R22.4 Localised swelling, mass and lump, lower limb	0.004	0.996	0.000
S62.60 Fracture of other finger (closed)	0.004	0.996	0.000
H18 Other disorders of cornea	0.004	0.996	0.000
S62.31 Fracture of other metacarpal bone (open)	0.003	0.996	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.000	0.996	0.003
S62.6 Fracture of other finger	0.003	0.997	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.997	0.003
S62 Fracture at wrist and hand level	0.003	0.997	0.000
R50.9 Fever, unspecified	0.003	0.997	0.000
H18.1 Bullous keratopathy	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.000	0.997	0.003
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.003	0.997	0.000
H18.7 Other corneal deformities	0.003	0.997	0.000
H18.3 Changes in corneal membranes	0.003	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.003	0.997	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.001	0.997	0.002
H18.4 Corneal degeneration	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.003	0.997	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.997	0.003
S62.61 Fracture of other finger (open)	0.003	0.997	0.000
S62.7 Multiple fractures of fingers	0.003	0.997	0.000
S62.10 Fracture of other carpal bone(s) (closed)	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
S62.4 Multiple fractures of metacarpal bones	0.002	0.997	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.997	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.997	0.002
S62.2 Fracture of first metacarpal bone	0.002	0.998	0.000
D12.6 Colon, unspecified	0.000	0.998	0.002
G31.8 Other specified degenerative diseases of nervous system	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
R10.1 Pain localised to upper abdomen	0.000	0.998	0.002
S62.5 Fracture of thumb	0.002	0.998	0.000
B44.1 Other pulmonary aspergillosis	0.000	0.998	0.002
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.002	0.998	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.998	0.002
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
G12.2 Motor neuron disease	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.002	0.998	0.000
S62.70 Multiple fractures of fingers (closed)	0.002	0.998	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.998	0.002
G31.0 Circumscribed brain atrophy	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.002	0.998	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.998	0.002
D68 Other coagulation defects	0.002	0.998	0.000
Y88 Sequelae of surgical and medical care as external cause	0.000	0.998	0.002
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
E07.9 Disorder of thyroid, unspecified	0.000	0.998	0.002
S62.21 Fracture of first metacarpal bone (open)	0.002	0.998	0.000
H72 Perforation of tympanic membrane	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.998	0.000
J47 Bronchiectasis	0.000	0.998	0.002
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.998	0.002
B44 Aspergillosis	0.000	0.998	0.002
S06.20 Diffuse brain injury (without open intracranial wound)	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
B44.9 Aspergillosis, unspecified	0.000	0.998	0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
Z45 Adjustment and management of implanted device	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.000	0.998	0.002
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.000	0.998	0.002
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
S52.50 Fracture of lower end of radius (closed)	0.002	0.998	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.998	0.000
B35.3 Tinea pedis	0.000	0.998	0.002
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.002	0.998	0.000
B37.8 Candidiasis of other sites	0.000	0.998	0.002
Y42.9 Other and unspecified hormone antagonists	0.000	0.998	0.002
Y42.4 Oral contraceptives	0.000	0.998	0.002
Y42.2 Antithyroid drugs	0.000	0.998	0.002
Y42.1 Thyroid hormones and substitutes	0.000	0.998	0.002
D68.9 Coagulation defect, unspecified	0.002	0.998	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.998	0.002
H72.1 Attic perforation of tympanic membrane	0.002	0.998	0.000
M35.7 Hypermobility syndrome	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
Y89 Sequelae of other external causes	0.000	0.998	0.002
B44.8 Other forms of aspergillosis	0.000	0.998	0.002
B44.7 Disseminated aspergillosis	0.000	0.998	0.002
B44.2 Tonsillar aspergillosis	0.000	0.998	0.002
B44.0 Invasive pulmonary aspergillosis	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.998	0.002
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
H72.8 Other perforations of tympanic membrane	0.002	0.998	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.998	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
R45.0 Nervousness	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.002
D12.8 Rectum	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.002	0.998	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.001
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
M24 Other specific joint derangements	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.001	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
M20-M25 Other joint disorders	0.002	0.998	0.000
S06.2 Diffuse brain injury	0.002	0.998	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.001	0.998	0.000
Z45.3 Adjustment and management of implanted hearing device	0.001	0.998	0.000
G30-G32 Other degenerative diseases of the nervous system	0.000	0.998	0.002
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.998	0.001
B35 Dermatophytosis	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.001	0.998	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.001	0.998	0.000
H21.0 Hyphaema	0.001	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.001	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
H17.8 Other corneal scars and opacities	0.001	0.998	0.000
H17.1 Other central corneal opacity	0.001	0.998	0.000
H17.0 Adherent leukoma	0.001	0.998	0.000
M24.6 Ankylosis of joint	0.001	0.998	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.001	0.998	0.000
M33 Dermatopolymyositis	0.001	0.998	0.000
S12 Fracture of neck	0.001	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.001	0.998	0.000
R45.2 Unhappiness	0.001	0.998	0.000
B49 Unspecified mycosis	0.000	0.998	0.001
S12.71 Multiple fractures of cervical spine (open)	0.001	0.998	0.000
B37.9 Candidiasis, unspecified	0.000	0.998	0.001
M33.1 Other dermatomyositis	0.001	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.001	0.998	0.000
Y87.2 Sequelae of events of undetermined intent	0.000	0.998	0.001
Y87.1 Sequelae of assault	0.000	0.998	0.001
Y87.0 Sequelae of intentional self-harm	0.000	0.998	0.001
Y89.9 Sequelae of unspecified external cause	0.000	0.998	0.001
Y89.1 Sequelae of war operations	0.000	0.998	0.001
Y89.0 Sequelae of legal intervention	0.000	0.998	0.001
Z02.8 Other examinations for administrative purposes	0.000	0.998	0.002
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.998	0.000
H15 Disorders of sclera	0.001	0.998	0.000
M35 Other systemic involvement of connective tissue	0.001	0.998	0.000
B35-B49 Mycoses	0.000	0.998	0.001
E21.0 Primary hyperparathyroidism	0.001	0.999	0.000
T51.0 Ethanol	0.000	0.999	0.001
S12.11 Fracture of second cervical vertebra (open)	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.001	0.999	0.000
S13.4 Sprain and strain of cervical spine	0.001	0.999	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.001	0.999	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.001	0.999	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.001	0.999	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.001	0.999	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.001	0.999	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.001	0.999	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.001	0.999	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.001	0.999	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
G30.8 Other Alzheimer's disease	0.000	0.999	0.001
G30.1 Alzheimer's disease with late onset	0.000	0.999	0.001
G30.0 Alzheimer's disease with early onset	0.000	0.999	0.001
G91.9 Hydrocephalus, unspecified	0.001	0.999	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.999	0.000
H21.4 Pupillary membranes	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
H21.2 Degeneration of iris and ciliary body	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
K02.9 Dental caries, unspecified	0.000	0.999	0.001
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.999	0.001
K91.5 Postcholecystectomy syndrome	0.000	0.999	0.001
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.999	0.001
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.999	0.001
M24.9 Joint derangement, unspecified	0.001	0.999	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.001	0.999	0.000
M24.2 Disorder of ligament	0.001	0.999	0.000
M24.0 Loose body in joint	0.001	0.999	0.000
Z45.1 Adjustment and management of infusion pump	0.001	0.999	0.000
M30 Polyarteritis nodosa and related conditions	0.001	0.999	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.999	0.000
I08.8 Other multiple valve diseases	0.001	0.999	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.999	0.001
Z04.3 Examination and observation following other accident	0.000	0.999	0.001
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.001	0.999	0.000
M32 Systemic lupus erythematosus	0.001	0.999	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.001	0.999	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.999	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.999	0.000
K91.1 Postgastric surgery syndromes	0.000	0.999	0.001
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.999	0.001
B35.9 Dermatophytosis, unspecified	0.000	0.999	0.001
B35.8 Other dermatophytoses	0.000	0.999	0.001
B35.6 Tinea cruris	0.000	0.999	0.001
B35.5 Tinea imbricata	0.000	0.999	0.001
B35.4 Tinea corporis	0.000	0.999	0.001
B35.2 Tinea manuum	0.000	0.999	0.001
B35.0 Tinea barbae and tinea capitis	0.000	0.999	0.001
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.001	0.999	0.000
I27.0 Primary pulmonary hypertension	0.000	0.999	0.001
K91.4 Colostomy and enterostomy malfunction	0.000	0.999	0.001
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system	0.001	0.999	0.000
M24.26 Disorder of ligament (Lower leg)	0.001	0.999	0.000
M24.79 Protrusio acetabuli-Site unspec	0.001	0.999	0.000
M24.78 Protrusio acetabuli-Other	0.001	0.999	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.001	0.999	0.000
M24.76 Protrusio acetabuli-Lower leg	0.001	0.999	0.000
M24.74 Protrusio acetabuli-Hand	0.001	0.999	0.000
M24.73 Protrusio acetabuli-Forearm	0.001	0.999	0.000
M24.72 Protrusio acetabuli-Upper arm	0.001	0.999	0.000
M24.71 Protrusio acetabuli-Shldr region	0.001	0.999	0.000
M24.70 Protrusio acetabuli-Mult sites	0.001	0.999	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations