TreeWAS – Variant ID: rs2081687

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Showing all nodes without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	1.000	0.000	0.000
K80.1 Calculus of gallbladder with other cholecystitis	1.000	0.000	0.000
K80 Cholelithiasis	1.000	0.000	0.000
E78.0 Pure hypercholesterolaemia	0.999	0.001	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.996	0.004	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.936	0.064	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.924	0.076	0.000
K80.8 Other cholelithiasis	0.909	0.091	0.000
K82 Other diseases of gallbladder	0.901	0.099	0.000
K82.4 Cholesterolosis of gallbladder	0.890	0.110	0.000
K66.0 Peritoneal adhesions	0.879	0.121	0.000
K66 Other disorders of peritoneum	0.871	0.129	0.000
K82.2 Perforation of gallbladder	0.820	0.180	0.000
K85 Acute pancreatitis	0.803	0.197	0.000
K65-K67 Diseases of peritoneum	0.797	0.203	0.000
K66.9 Disorder of peritoneum, unspecified	0.769	0.231	0.000
K66.8 Other specified disorders of peritoneum	0.767	0.233	0.000
K66.1 Haemoperitoneum	0.757	0.243	0.000
Chapter XI Diseases of the digestive system	0.746	0.254	0.000
K70-K77 Diseases of liver	0.732	0.268	0.000
K80.3 Calculus of bile duct with cholangitis	0.717	0.283	0.000
K76 Other diseases of liver	0.703	0.297	0.000
K75 Other inflammatory liver diseases	0.692	0.308	0.000
K80.4 Calculus of bile duct with cholecystitis	0.683	0.317	0.000
K85.1 Biliary acute pancreatitis	0.683	0.317	0.000
K85.2 Alcohol-induced acute pancreatitis	0.682	0.318	0.000
K82.0 Obstruction of gallbladder	0.671	0.329	0.000
K75.8 Other specified inflammatory liver diseases	0.667	0.333	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.665	0.335	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.662	0.338	0.000
K76.8 Other specified diseases of liver	0.661	0.339	0.000
K85.0 Idiopathic acute pancreatitis	0.599	0.401	0.000
K74 Fibrosis and cirrhosis of liver	0.599	0.401	0.000
K82.9 Disease of gallbladder, unspecified	0.580	0.419	0.000
K85.8 Other acute pancreatitis	0.577	0.423	0.000
K85.3 Drug-induced acute pancreatitis	0.576	0.424	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.571	0.428	0.000
K75.4 Autoimmune hepatitis	0.567	0.433	0.000
K76.7 Hepatorenal syndrome	0.566	0.434	0.000
K65 Peritonitis	0.565	0.435	0.000
K71 Toxic liver disease	0.564	0.436	0.000
K73 Chronic hepatitis, not elsewhere classified	0.562	0.438	0.000
K82.3 Fistula of gallbladder	0.561	0.439	0.000
K74.5 Biliary cirrhosis, unspecified	0.547	0.453	0.000
K77 Liver disorders in diseases classified elsewhere	0.525	0.475	0.000
K75.9 Inflammatory liver disease, unspecified	0.525	0.475	0.000
K86 Other diseases of pancreas	0.518	0.482	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.514	0.486	0.000
K76.5 Hepatic veno-occlusive disease	0.504	0.496	0.000
K76.4 Peliosis hepatis	0.504	0.496	0.000
K76.3 Infarction of liver	0.504	0.496	0.000
K76.2 Central haemorrhagic necrosis of liver	0.504	0.496	0.000
K74.1 Hepatic sclerosis	0.500	0.500	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.499	0.500	0.000
K75.2 Nonspecific reactive hepatitis	0.496	0.504	0.000
K75.1 Phlebitis of portal vein	0.496	0.504	0.000
K65.8 Other peritonitis	0.489	0.511	0.000
K82.8 Other specified diseases of gallbladder	0.483	0.517	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.475	0.525	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.475	0.525	0.000
K86.2 Cyst of pancreas	0.468	0.532	0.000
K85.9 Acute pancreatitis, unspecified	0.462	0.537	0.000
K73.9 Chronic hepatitis, unspecified	0.443	0.556	0.000
K86.3 Pseudocyst of pancreas	0.439	0.561	0.000
K76.1 Chronic passive congestion of liver	0.433	0.567	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.431	0.569	0.000
K71.0 Toxic liver disease with cholestasis	0.431	0.569	0.000
K74.4 Secondary biliary cirrhosis	0.429	0.571	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.429	0.571	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.424	0.576	0.000
K82.1 Hydrops of gallbladder	0.410	0.589	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.410	0.590	0.000
K67.3 Tuberculous peritonitis	0.410	0.590	0.000
K67.2 Syphilitic peritonitis	0.410	0.590	0.000
K67.1 Gonococcal peritonitis	0.410	0.590	0.000
K67.0 Chlamydial peritonitis	0.410	0.590	0.000
K74.3 Primary biliary cirrhosis	0.406	0.594	0.000
K71.9 Toxic liver disease, unspecified	0.404	0.596	0.000
K71.8 Toxic liver disease with other disorders of liver	0.404	0.596	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.404	0.596	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.404	0.596	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.404	0.596	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.404	0.596	0.000
K71.2 Toxic liver disease with acute hepatitis	0.404	0.596	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.403	0.597	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.403	0.597	0.000
K76.6 Portal hypertension	0.390	0.610	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.389	0.611	0.000
K81 Cholecystitis	0.387	0.613	0.000
K74.0 Hepatic fibrosis	0.379	0.621	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.376	0.623	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.376	0.623	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.375	0.625	0.000
K65.9 Peritonitis, unspecified	0.372	0.628	0.000
K76.9 Liver disease, unspecified	0.352	0.648	0.000
K83 Other diseases of biliary tract	0.314	0.686	0.000
K72 Hepatic failure, not elsewhere classified	0.311	0.689	0.000
K70 Alcoholic liver disease	0.307	0.693	0.000
K75.0 Abscess of liver	0.289	0.711	0.000
K81.8 Other cholecystitis	0.282	0.718	0.000
K65.0 Acute peritonitis	0.276	0.724	0.000
K86.9 Disease of pancreas, unspecified	0.276	0.724	0.000
K81.9 Cholecystitis, unspecified	0.274	0.726	0.000
K70.0 Alcoholic fatty liver	0.268	0.732	0.000
K81.1 Chronic cholecystitis	0.263	0.737	0.000
K83.1 Obstruction of bile duct	0.262	0.738	0.000
K86.1 Other chronic pancreatitis	0.258	0.742	0.000
K35-K38 Diseases of appendix	0.245	0.755	0.000
K86.8 Other specified diseases of pancreas	0.237	0.763	0.000
K74.6 Other and unspecified cirrhosis of liver	0.237	0.763	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.233	0.767	0.000
K83.3 Fistula of bile duct	0.230	0.770	0.000
K83.5 Biliary cyst	0.225	0.775	0.000
K83.2 Perforation of bile duct	0.225	0.775	0.000
K36 Other appendicitis	0.218	0.782	0.000
K72.1 Chronic hepatic failure	0.207	0.793	0.000
K83.4 Spasm of sphincter of Oddi	0.207	0.793	0.000
K72.0 Acute and subacute hepatic failure	0.205	0.794	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.205	0.795	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.203	0.797	0.000
K70.3 Alcoholic cirrhosis of liver	0.194	0.806	0.000
K05 Gingivitis and periodontal diseases	0.186	0.814	0.000
K11 Diseases of salivary glands	0.185	0.815	0.000
K83.9 Disease of biliary tract, unspecified	0.180	0.820	0.000
K05.1 Chronic gingivitis	0.178	0.822	0.000
K11.1 Hypertrophy of salivary gland	0.176	0.824	0.000
K70.9 Alcoholic liver disease, unspecified	0.173	0.827	0.000
K08 Other disorders of teeth and supporting structures	0.170	0.830	0.000
K83.8 Other specified diseases of biliary tract	0.165	0.835	0.000
K11.5 Sialolithiasis	0.165	0.835	0.000
K05.6 Periodontal disease, unspecified	0.163	0.837	0.000
K03 Other diseases of hard tissues of teeth	0.161	0.839	0.000
K11.9 Disease of salivary gland, unspecified	0.157	0.843	0.000
K07 Dentofacial anomalies [including malocclusion]	0.156	0.844	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.156	0.844	0.000
K14 Diseases of tongue	0.156	0.844	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.153	0.847	0.000
K70.4 Alcoholic hepatic failure	0.152	0.848	0.000
K00 Disorders of tooth development and eruption	0.149	0.851	0.000
K70.1 Alcoholic hepatitis	0.146	0.854	0.000
K14.9 Disease of tongue, unspecified	0.140	0.860	0.000
K11.3 Abscess of salivary gland	0.139	0.861	0.000
K05.4 Periodontosis	0.137	0.863	0.000
K07.6 Temporomandibular joint disorders	0.136	0.864	0.000
K05.2 Acute periodontitis	0.134	0.866	0.000
K11.4 Fistula of salivary gland	0.133	0.867	0.000
K11.0 Atrophy of salivary gland	0.133	0.867	0.000
K11.7 Disturbances of salivary secretion	0.132	0.867	0.000
K03.6 Deposits [accretions] on teeth	0.128	0.872	0.000
K05.0 Acute gingivitis	0.127	0.873	0.000
K02 Dental caries	0.127	0.873	0.000
K07.0 Major anomalies of jaw size	0.126	0.874	0.000
K03.3 Pathological resorption of teeth	0.124	0.876	0.000
K38 Other diseases of appendix	0.123	0.877	0.000
K05.5 Other periodontal diseases	0.122	0.878	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.122	0.878	0.000
K14.1 Geographic tongue	0.121	0.879	0.000
K14.6 Glossodynia	0.120	0.880	0.000
K14.2 Median rhomboid glossitis	0.119	0.881	0.000
K07.3 Anomalies of tooth position	0.117	0.883	0.000
K12 Stomatitis and related lesions	0.117	0.883	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.116	0.884	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.116	0.884	0.000
K03.5 Ankylosis of teeth	0.116	0.884	0.000
K03.4 Hypercementosis	0.116	0.884	0.000
K03.2 Erosion of teeth	0.116	0.884	0.000
K03.1 Abrasion of teeth	0.116	0.884	0.000
K03.0 Excessive attrition of teeth	0.116	0.884	0.000
K07.4 Malocclusion, unspecified	0.116	0.884	0.000
K00.1 Supernumerary teeth	0.114	0.885	0.000
K00.0 Anodontia	0.113	0.887	0.000
K07.8 Other dentofacial anomalies	0.112	0.888	0.000
K07.5 Dentofacial functional abnormalities	0.112	0.888	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.112	0.888	0.000
K02.8 Other dental caries	0.112	0.888	0.000
K14.5 Plicated tongue	0.112	0.888	0.000
K14.4 Atrophy of tongue papillae	0.112	0.888	0.000
K14.3 Hypertrophy of tongue papillae	0.112	0.888	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.110	0.890	0.000
K00.8 Other disorders of tooth development	0.107	0.893	0.000
K00.7 Teething syndrome	0.107	0.893	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.107	0.893	0.000
K00.4 Disturbances in tooth formation	0.107	0.893	0.000
K00.3 Mottled teeth	0.107	0.893	0.000
K00.2 Abnormalities of size and form of teeth	0.107	0.893	0.000
K07.9 Dentofacial anomaly, unspecified	0.106	0.894	0.000
K11.8 Other diseases of salivary glands	0.103	0.897	0.000
K00.9 Disorder of tooth development, unspecified	0.103	0.897	0.000
K07.2 Anomalies of dental arch relationship	0.102	0.897	0.000
K11.6 Mucocele of salivary gland	0.102	0.898	0.000
K09 Cysts of oral region, not elsewhere classified	0.100	0.900	0.000
K00.6 Disturbances in tooth eruption	0.100	0.900	0.000
K50-K52 Noninfective enteritis and colitis	0.099	0.900	0.000
K14.0 Glossitis	0.099	0.901	0.000
K12.2 Cellulitis and abscess of mouth	0.098	0.902	0.000
K72.9 Hepatic failure, unspecified	0.097	0.902	0.000
K38.2 Diverticulum of appendix	0.097	0.903	0.000
K05.22 Aggressive periodontitis, generalized	0.096	0.904	0.000
K02.5 Caries with pulp exposure	0.091	0.909	0.000
K02.4 Odontoclasia	0.091	0.909	0.000
K02.3 Arrested dental caries	0.091	0.909	0.000
K02.2 Caries of cementum	0.091	0.909	0.000
K02.0 Caries limited to enamel	0.091	0.909	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.090	0.909	0.000
K38.0 Hyperplasia of appendix	0.090	0.910	0.000
K10 Other diseases of jaws	0.090	0.910	0.000
K38.3 Fistula of appendix	0.089	0.911	0.000
K02.1 Caries of dentin	0.088	0.911	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.085	0.914	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.085	0.915	0.000
K38.9 Disease of appendix, unspecified	0.081	0.919	0.000
K12.0 Recurrent oral aphthae	0.079	0.921	0.000
K01 Embedded and impacted teeth	0.073	0.927	0.000
K12.3 Oral mucositis (ulcerative)	0.068	0.932	0.000
K90-K93 Other diseases of the digestive system	0.068	0.932	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.067	0.933	0.000
K13 Other diseases of lip and oral mucosa	0.067	0.933	0.000
K38.8 Other specified diseases of appendix	0.066	0.934	0.000
K10.2 Inflammatory conditions of jaws	0.066	0.934	0.000
K10.1 Giant cell granuloma, central	0.065	0.935	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.064	0.936	0.000
K38.1 Appendicular concretions	0.062	0.937	0.000
K35 Acute appendicitis	0.063	0.937	0.000
K10.0 Developmental disorders of jaws	0.062	0.938	0.000
K08.3 Retained dental root	0.062	0.938	0.000
K06.0 Gingival recession	0.061	0.938	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.061	0.939	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.059	0.940	0.001
K10.9 Disease of jaws, unspecified	0.059	0.941	0.000
E78.4 Other hyperlipidaemia	0.059	0.941	0.000
K05.3 Chronic periodontitis	0.058	0.941	0.000
K35.8 Acute appendicitis, other and unspecified	0.056	0.944	0.000
K12.1 Other forms of stomatitis	0.053	0.947	0.000
K09.2 Other cysts of jaw	0.053	0.947	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.053	0.947	0.000
K09.0 Developmental odontogenic cysts	0.053	0.947	0.000
K13.5 Oral submucous fibrosis	0.052	0.948	0.000
K83.0 Cholangitis	0.051	0.949	0.000
E78.3 Hyperchylomicronaemia	0.051	0.949	0.000
K10.3 Alveolitis of jaws	0.050	0.949	0.000
K10.8 Other specified diseases of jaws	0.050	0.950	0.000
K37 Unspecified appendicitis	0.050	0.950	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.049	0.950	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.049	0.951	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.048	0.952	0.000
K13.3 Hairy leukoplakia	0.048	0.952	0.000
K13.1 Cheek and lip biting	0.048	0.952	0.000
K09.9 Cyst of oral region, unspecified	0.047	0.953	0.000
K81.0 Acute cholecystitis	0.047	0.953	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.047	0.953	0.000
E78.6 Lipoprotein deficiency	0.045	0.955	0.000
K01.0 Embedded teeth	0.044	0.956	0.000
K06.1 Gingival enlargement	0.043	0.956	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.043	0.957	0.000
E78.8 Other disorders of lipoprotein metabolism	0.042	0.958	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.039	0.960	0.000
K13.0 Diseases of lips	0.039	0.961	0.000
K50 Crohn's disease [regional enteritis]	0.038	0.962	0.000
K11.2 Sialoadenitis	0.038	0.962	0.000
E78.2 Mixed hyperlipidaemia	0.037	0.963	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.035	0.965	0.000
K93.1 Megacolon in Chagas' disease	0.035	0.965	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.035	0.965	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.034	0.965	0.000
K35.3 Acute appendicitis with localized peritonitis	0.033	0.967	0.000
K50.8 Other Crohn's disease	0.032	0.968	0.000
E78.1 Pure hyperglyceridaemia	0.031	0.969	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.031	0.969	0.000
N84.1 Polyp of cervix uteri	0.000	0.969	0.031
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.029	0.971	0.000
Q60-Q64 Congenital malformations of the urinary system	0.028	0.972	0.000
Q63 Other congenital malformations of kidney	0.028	0.972	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.027	0.973	0.000
Q50-Q56 Congenital malformations of genital organs	0.027	0.973	0.000
Q80-Q89 Other congenital malformations	0.026	0.974	0.000
K04 Diseases of pulp and periapical tissues	0.026	0.974	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.026	0.974	0.000
K50.1 Crohn's disease of large intestine	0.024	0.976	0.000
Q00-Q07 Congenital malformations of the nervous system	0.024	0.976	0.000
K04.6 Periapical abscess with sinus	0.024	0.976	0.000
Q25 Congenital malformations of great arteries	0.024	0.976	0.000
Q54 Hypospadias	0.024	0.976	0.000
C16.9 Stomach, unspecified	0.000	0.976	0.024
K13.6 Irritative hyperplasia of oral mucosa	0.023	0.976	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.024	0.976	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.023	0.977	0.000
Q82 Other congenital malformations of skin	0.023	0.977	0.000
K51 Ulcerative colitis	0.023	0.977	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.023	0.977	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.023	0.977	0.000
Q63.0 Accessory kidney	0.023	0.977	0.000
Q55 Other congenital malformations of male genital organs	0.023	0.977	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.023	0.977	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.023	0.977	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.023	0.977	0.000
Q63.8 Other specified congenital malformations of kidney	0.022	0.977	0.000
Q24 Other congenital malformations of heart	0.022	0.978	0.000
Q53 Undescended testicle	0.022	0.978	0.000
Q63.2 Ectopic kidney	0.022	0.978	0.000
K14.8 Other diseases of tongue	0.022	0.978	0.000
Q27 Other congenital malformations of peripheral vascular system	0.021	0.978	0.000
K52 Other non-infective gastro-enteritis and colitis	0.021	0.979	0.000
Q05 Spina bifida	0.021	0.979	0.000
Q83 Congenital malformations of breast	0.021	0.979	0.000
Q24.8 Other specified congenital malformations of heart	0.021	0.979	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.021	0.979	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.021	0.979	0.000
Q52 Other congenital malformations of female genitalia	0.021	0.979	0.000
Q65 Congenital deformities of hip	0.021	0.979	0.000
Q55.6 Other congenital malformations of penis	0.021	0.979	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.021	0.979	0.000
Q82.5 Congenital nonneoplastic naevus	0.021	0.979	0.000
Q54.0 Hypospadias, balanic	0.020	0.979	0.000
K90 Intestinal malabsorption	0.021	0.979	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.020	0.980	0.000
Q25.0 Patent ductus arteriosus	0.020	0.980	0.000
Q63.3 Hyperplastic and giant kidney	0.020	0.980	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.020	0.980	0.000
Q54.1 Hypospadias, penile	0.020	0.980	0.000
Q35-Q37 Cleft lip and cleft palate	0.020	0.980	0.000
Q06 Other congenital malformations of spinal cord	0.020	0.980	0.000
K50.0 Crohn's disease of small intestine	0.020	0.980	0.000
Q25.4 Other congenital malformations of aorta	0.019	0.981	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.019	0.981	0.000
K51.4 Pseudopolyposis of colon	0.019	0.981	0.000
Q65.8 Other congenital deformities of hip	0.019	0.981	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.019	0.981	0.000
Q84 Other congenital malformations of integument	0.019	0.981	0.000
Q81 Epidermolysis bullosa	0.019	0.981	0.000
Q80 Congenital ichthyosis	0.019	0.981	0.000
Q62.5 Duplication of ureter	0.019	0.981	0.000
Q25.6 Stenosis of pulmonary artery	0.019	0.981	0.000
K04.3 Abnormal hard tissue formation in pulp	0.019	0.981	0.000
K04.2 Pulp degeneration	0.019	0.981	0.000
K04.1 Necrosis of pulp	0.019	0.981	0.000
Q26 Congenital malformations of great veins	0.019	0.981	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.019	0.981	0.000
Q64 Other congenital malformations of urinary system	0.019	0.981	0.000
Q40 Other congenital malformations of upper alimentary tract	0.019	0.981	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.019	0.981	0.000
Q66 Congenital deformities of feet	0.019	0.981	0.000
Q03 Congenital hydrocephalus	0.018	0.981	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.019	0.981	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.018	0.981	0.000
K52.3 Indeterminate colitis	0.018	0.981	0.000
Q53.9 Undescended testicle, unspecified	0.018	0.982	0.000
Q25.3 Stenosis of aorta	0.018	0.982	0.000
Q25.1 Coarctation of aorta	0.018	0.982	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.018	0.982	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.018	0.982	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.018	0.982	0.000
Q89 Other congenital malformations, not elsewhere classified	0.018	0.982	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.018	0.982	0.000
Q83.1 Accessory breast	0.018	0.982	0.000
Q82.8 Other specified congenital malformations of skin	0.018	0.982	0.000
Q54.9 Hypospadias, unspecified	0.018	0.982	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.018	0.982	0.000
Q01 Encephalocele	0.018	0.982	0.000
Q00 Anencephaly and similar malformations	0.018	0.982	0.000
Q02 Microcephaly	0.018	0.982	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.018	0.982	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.017	0.982	0.000
Q25.8 Other congenital malformations of great arteries	0.017	0.982	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.017	0.982	0.000
Q25.5 Atresia of pulmonary artery	0.017	0.982	0.000
Q25.2 Atresia of aorta	0.017	0.982	0.000
Q24.4 Congenital subaortic stenosis	0.017	0.982	0.000
Q82.2 Mastocytosis	0.017	0.982	0.000
Q54.8 Other hypospadias	0.017	0.983	0.000
Q54.4 Congenital chordee	0.017	0.983	0.000
Q54.3 Hypospadias, perineal	0.017	0.983	0.000
Q54.2 Hypospadias, penoscrotal	0.017	0.983	0.000
Q52.1 Doubling of vagina	0.017	0.983	0.000
Q53.1 Undescended testicle, unilateral	0.017	0.983	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.017	0.983	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.017	0.983	0.000
Q82.9 Congenital malformation of skin, unspecified	0.017	0.983	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.017	0.983	0.000
Q82.3 Incontinentia pigmenti	0.017	0.983	0.000
Q82.1 Xeroderma pigmentosum	0.017	0.983	0.000
Q82.0 Hereditary lymphoedema	0.017	0.983	0.000
Q74 Other congenital malformations of limb(s)	0.017	0.983	0.000
Q87.4 Marfan's syndrome	0.017	0.983	0.000
Q68 Other congenital musculoskeletal deformities	0.017	0.983	0.000
Q05.9 Spina bifida, unspecified	0.017	0.983	0.000
Q28 Other congenital malformations of circulatory system	0.017	0.983	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.017	0.983	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.017	0.983	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.017	0.983	0.000
Q55.9 Congenital malformation of male genital organ, unspecified	0.017	0.983	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.017	0.983	0.000
Q55.5 Congenital absence and aplasia of penis	0.017	0.983	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.017	0.983	0.000
Q55.3 Atresia of vas deferens	0.017	0.983	0.000
Q55.1 Hypoplasia of testis and scrotum	0.017	0.983	0.000
Q55.0 Absence and aplasia of testis	0.017	0.983	0.000
Q75 Other congenital malformations of skull and face bones	0.017	0.983	0.000
Q73 Reduction defects of unspecified limb	0.017	0.983	0.000
Q72 Reduction defects of lower limb	0.017	0.983	0.000
Q71 Reduction defects of upper limb	0.017	0.983	0.000
Q70 Syndactyly	0.017	0.983	0.000
Q69 Polydactyly	0.017	0.983	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.017	0.983	0.000
Q06.8 Other specified congenital malformations of spinal cord	0.016	0.983	0.000
Q60.2 Renal agenesis, unspecified	0.016	0.983	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.016	0.983	0.000
Q62.8 Other congenital malformations of ureter	0.016	0.983	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.016	0.983	0.000
Q62.6 Malposition of ureter	0.016	0.983	0.000
Q62.4 Agenesis of ureter	0.016	0.983	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.016	0.983	0.000
Q62.2 Congenital megaloureter	0.016	0.983	0.000
Q62.1 Atresia and stenosis of ureter	0.016	0.983	0.000
Q62.0 Congenital hydronephrosis	0.016	0.983	0.000
Q51 Congenital malformations of uterus and cervix	0.016	0.983	0.000
Q24.6 Congenital heart block	0.016	0.984	0.000
Q24.3 Pulmonary infundibular stenosis	0.016	0.984	0.000
Q24.2 Cor triatriatum	0.016	0.984	0.000
Q24.1 Levocardia	0.016	0.984	0.000
Q22.5 Ebstein's anomaly	0.016	0.984	0.000
Q24.0 Dextrocardia	0.016	0.984	0.000
Q45 Other congenital malformations of digestive system	0.016	0.984	0.000
Q04 Other congenital malformations of brain	0.016	0.984	0.000
Q14 Congenital malformations of posterior segment of eye	0.016	0.984	0.000
Q53.2 Undescended testicle, bilateral	0.016	0.984	0.000
Q53.0 Ectopic testis	0.016	0.984	0.000
Q12 Congenital lens malformations	0.016	0.984	0.000
Q24.5 Malformation of coronary vessels	0.016	0.984	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.016	0.984	0.000
Q21 Congenital malformations of cardiac septa	0.016	0.984	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.016	0.984	0.000
Q83.3 Accessory nipple	0.016	0.984	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.016	0.984	0.000
Q43 Other congenital malformations of intestine	0.016	0.984	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.016	0.984	0.000
Q27.4 Congenital phlebectasia	0.016	0.984	0.000
Q27.2 Other congenital malformations of renal artery	0.016	0.984	0.000
Q27.1 Congenital renal artery stenosis	0.016	0.984	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.016	0.984	0.000
Q07 Other congenital malformations of nervous system	0.016	0.984	0.000
Q78 Other osteochondrodysplasias	0.016	0.984	0.000
Q39 Congenital malformations of oesophagus	0.016	0.984	0.000
Q66.2 Metatarsus varus	0.015	0.985	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.015	0.985	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.015	0.985	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.015	0.985	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.015	0.985	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.015	0.985	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.015	0.985	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.015	0.985	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.015	0.985	0.000
Q83.9 Congenital malformation of breast, unspecified	0.015	0.985	0.000
Q83.2 Absent nipple	0.015	0.985	0.000
Q83.0 Congenital absence of breast with absent nipple	0.015	0.985	0.000
Q38.7 Pharyngeal pouch	0.015	0.985	0.000
Q27.3 Peripheral arteriovenous malformation	0.015	0.985	0.000
Q60.6 Potter's syndrome	0.015	0.985	0.000
Q60.5 Renal hypoplasia, unspecified	0.015	0.985	0.000
Q60.4 Renal hypoplasia, bilateral	0.015	0.985	0.000
Q60.3 Renal hypoplasia, unilateral	0.015	0.985	0.000
Q60.1 Renal agenesis, bilateral	0.015	0.985	0.000
Q61 Cystic kidney disease	0.015	0.985	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.015	0.985	0.000
Q40.1 Congenital hiatus hernia	0.015	0.985	0.000
Q34 Other congenital malformations of respiratory system	0.015	0.985	0.000
Q33 Congenital malformations of lung	0.015	0.985	0.000
Q32 Congenital malformations of trachea and bronchus	0.015	0.985	0.000
Q31 Congenital malformations of larynx	0.015	0.985	0.000
Q30 Congenital malformations of nose	0.015	0.985	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.015	0.985	0.000
Q52.8 Other specified congenital malformations of female genitalia	0.015	0.985	0.000
Q52.7 Other congenital malformations of vulva	0.015	0.985	0.000
Q52.6 Congenital malformation of clitoris	0.015	0.985	0.000
Q52.4 Other congenital malformations of vagina	0.015	0.985	0.000
Q52.3 Imperforate hymen	0.015	0.985	0.000
Q52.2 Congenital rectovaginal fistula	0.015	0.985	0.000
Q52.0 Congenital absence of vagina	0.015	0.985	0.000
Q65.9 Congenital deformity of hip, unspecified	0.015	0.985	0.000
Q65.6 Unstable hip	0.015	0.985	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.015	0.985	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.015	0.985	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.015	0.985	0.000
Q65.2 Congenital dislocation of hip, unspecified	0.015	0.985	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.015	0.985	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.015	0.985	0.000
Q66.3 Other congenital varus deformities of feet	0.015	0.985	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.015	0.985	0.000
Q13 Congenital malformations of anterior segment of eye	0.015	0.985	0.000
Q66.9 Congenital deformity of feet, unspecified	0.015	0.985	0.000
K90.3 Pancreatic steatorrhoea	0.015	0.985	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.015	0.985	0.000
K90.1 Tropical sprue	0.015	0.985	0.000
Q85 Phakomatoses, not elsewhere classified	0.015	0.985	0.000
Q23 Congenital malformations of aortic and mitral valves	0.015	0.985	0.000
Q77.4 Achondroplasia	0.015	0.985	0.000
Q60.0 Renal agenesis, unilateral	0.015	0.985	0.000
Q35 Cleft palate	0.014	0.985	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.014	0.985	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.014	0.985	0.000
Q22.6 Hypoplastic right heart syndrome	0.014	0.985	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations