TreeWAS – Variant ID: rs2099613

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K42.9 Umbilical hernia without obstruction or gangrene	0.062	0.938	0.000
K42 Umbilical hernia	0.024	0.976	0.000
K70.4 Alcoholic hepatic failure	0.023	0.977	0.000
K70.3 Alcoholic cirrhosis of liver	0.022	0.978	0.000
K70 Alcoholic liver disease	0.022	0.978	0.000
K74.6 Other and unspecified cirrhosis of liver	0.021	0.979	0.000
K74 Fibrosis and cirrhosis of liver	0.020	0.980	0.000
K74.0 Hepatic fibrosis	0.019	0.981	0.000
K70-K77 Diseases of liver	0.019	0.981	0.000
K42.1 Umbilical hernia with gangrene	0.017	0.983	0.000
R73.0 Abnormal glucose tolerance test	0.015	0.985	0.000
K74.4 Secondary biliary cirrhosis	0.014	0.986	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.014	0.986	0.000
K74.1 Hepatic sclerosis	0.014	0.986	0.000
K72 Hepatic failure, not elsewhere classified	0.014	0.986	0.000
K70.9 Alcoholic liver disease, unspecified	0.014	0.986	0.000
K71 Toxic liver disease	0.014	0.986	0.000
K70.0 Alcoholic fatty liver	0.014	0.986	0.000
K73 Chronic hepatitis, not elsewhere classified	0.014	0.986	0.000
K77 Liver disorders in diseases classified elsewhere	0.013	0.986	0.000
K74.5 Biliary cirrhosis, unspecified	0.013	0.987	0.000
K76 Other diseases of liver	0.013	0.987	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.013	0.987	0.000
K72.9 Hepatic failure, unspecified	0.013	0.987	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.012	0.988	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.012	0.988	0.000
R73 Elevated blood glucose level	0.012	0.988	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.012	0.988	0.000
K70.1 Alcoholic hepatitis	0.011	0.988	0.000
K76.1 Chronic passive congestion of liver	0.011	0.989	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.011	0.989	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.011	0.989	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.011	0.989	0.000
K76.7 Hepatorenal syndrome	0.011	0.989	0.000
K75 Other inflammatory liver diseases	0.011	0.989	0.000
K73.9 Chronic hepatitis, unspecified	0.011	0.989	0.000
S92.00 Fracture of calcaneus (closed)	0.011	0.989	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.010	0.989	0.000
K72.1 Chronic hepatic failure	0.010	0.989	0.000
R76 Other abnormal immunological findings in serum	0.010	0.990	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.990	0.010
K71.9 Toxic liver disease, unspecified	0.010	0.990	0.000
K71.8 Toxic liver disease with other disorders of liver	0.010	0.990	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.010	0.990	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.010	0.990	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.010	0.990	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.010	0.990	0.000
K71.2 Toxic liver disease with acute hepatitis	0.010	0.990	0.000
K71.0 Toxic liver disease with cholestasis	0.010	0.990	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.010	0.990	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.010	0.990	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.010	0.990	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
R76.0 Raised antibody titer	0.010	0.990	0.000
K76.5 Hepatic veno-occlusive disease	0.009	0.991	0.000
K76.4 Peliosis hepatis	0.009	0.991	0.000
K76.3 Infarction of liver	0.009	0.991	0.000
K76.2 Central haemorrhagic necrosis of liver	0.009	0.991	0.000
R71 Abnormality of red blood cells	0.009	0.991	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.009	0.991	0.000
R79 Other abnormal findings of blood chemistry	0.009	0.991	0.000
L81.4 Other melanin hyperpigmentation	0.000	0.991	0.009
K74.3 Primary biliary cirrhosis	0.009	0.991	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.009	0.991	0.000
K75.8 Other specified inflammatory liver diseases	0.009	0.991	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.008	0.992	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.008	0.992	0.000
C77.0 Lymph nodes of head, face and neck	0.008	0.992	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.008	0.992	0.000
R76.8 Other specified abnormal immunological findings in serum	0.008	0.992	0.000
K75.2 Nonspecific reactive hepatitis	0.008	0.992	0.000
K75.1 Phlebitis of portal vein	0.008	0.992	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.008	0.992	0.000
K72.0 Acute and subacute hepatic failure	0.008	0.992	0.000
R76.2 False-positive serological test for syphilis	0.008	0.992	0.000
R76.1 Abnormal reaction to tuberculin test	0.008	0.992	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.008	0.992	0.000
K46 Unspecified abdominal hernia	0.008	0.992	0.000
K75.4 Autoimmune hepatitis	0.007	0.992	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.007	0.993	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.007	0.993	0.000
B25.9 Cytomegaloviral disease, unspecified	0.007	0.993	0.000
R70.1 Abnormal plasma viscosity	0.007	0.993	0.000
K40-K46 Hernia	0.007	0.993	0.000
R79.0 Abnormal level of blood mineral	0.007	0.993	0.000
K76.6 Portal hypertension	0.007	0.993	0.000
R77 Other abnormalities of plasma proteins	0.006	0.993	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.006	0.994	0.000
K44 Diaphragmatic hernia	0.006	0.994	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.006	0.994	0.000
S92.0 Fracture of calcaneus	0.006	0.994	0.000
K76.9 Liver disease, unspecified	0.006	0.994	0.000
R74 Abnormal serum enzyme levels	0.006	0.994	0.000
R78.0 Finding of alcohol in blood	0.006	0.994	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.006	0.994	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.006	0.994	0.000
R78.6 Finding of steroid agent in blood	0.006	0.994	0.000
R78.5 Finding of psychotropic drug in blood	0.006	0.994	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.006	0.994	0.000
R78.3 Finding of hallucinogen in blood	0.006	0.994	0.000
R78.2 Finding of cocaine in blood	0.006	0.994	0.000
R78.1 Finding of opiate drug in blood	0.006	0.994	0.000
K75.0 Abscess of liver	0.006	0.994	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.006	0.994	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.006	0.994	0.000
K75.9 Inflammatory liver disease, unspecified	0.006	0.994	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.006	0.994	0.000
C83.0 Small cell (diffuse)	0.006	0.994	0.000
C83.1 Small cleaved cell (diffuse)	0.005	0.995	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.005	0.995	0.000
H18.6 Keratoconus	0.000	0.995	0.005
K44.1 Diaphragmatic hernia with gangrene	0.005	0.995	0.000
R77.2 Abnormality of alphafetoprotein	0.005	0.995	0.000
R77.0 Abnormality of albumin	0.005	0.995	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.005	0.995	0.000
R77.1 Abnormality of globulin	0.005	0.995	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.005	0.995	0.000
S92.01 Fracture of calcaneus (open)	0.005	0.995	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.005	0.995	0.000
C83.7 Burkitt's tumour	0.005	0.995	0.000
R77.9 Abnormality of plasma protein, unspecified	0.004	0.995	0.000
K45 Other abdominal hernia	0.004	0.995	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.004	0.996	0.000
C83.6 Undifferentiated (diffuse)	0.004	0.996	0.000
C83.5 Lymphoblastic (diffuse)	0.004	0.996	0.000
C83.4 Immunoblastic (diffuse)	0.004	0.996	0.000
C83.2 Mixed small and large cell (diffuse)	0.004	0.996	0.000
B97 Viral agents as the cause of diseases classified to other chapters	0.004	0.996	0.000
M84.03 Malunion of fracture (Forearm)	0.000	0.996	0.004
C83.3 Large cell (diffuse)	0.004	0.996	0.000
H18.4 Corneal degeneration	0.000	0.996	0.004
H43.8 Other disorders of vitreous body	0.000	0.996	0.004
H65.3 Chronic mucoid otitis media	0.000	0.996	0.004
B02.9 Zoster without complication	0.000	0.996	0.004
H18.9 Disorder of cornea, unspecified	0.000	0.996	0.004
B25 Cytomegaloviral disease	0.004	0.996	0.000
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters	0.004	0.996	0.000
R77.8 Other specified abnormalities of plasma proteins	0.004	0.996	0.000
H18 Other disorders of cornea	0.000	0.996	0.004
K41 Femoral hernia	0.004	0.996	0.000
H18.2 Other corneal oedema	0.000	0.996	0.004
M84.0 Malunion of fracture	0.000	0.996	0.004
B97.1 Enterovirus as the cause of diseases classified to other chapters	0.004	0.996	0.000
K45.1 Other specified abdominal hernia with gangrene	0.003	0.996	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.004	0.996	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
C67.1 Dome of bladder	0.004	0.996	0.000
N20.2 Calculus of kidney with calculus of ureter	0.004	0.996	0.000
Z86.5 Personal history of other mental and behavioural disorders	0.000	0.997	0.003
C67.2 Lateral wall of bladder	0.003	0.997	0.000
K35.8 Acute appendicitis, other and unspecified	0.003	0.997	0.000
B97.6 Parvovirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
B97.5 Reovirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
B97.3 Retrovirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
B97.2 Coronavirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
B97.0 Adenovirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.003	0.997	0.000
K76.8 Other specified diseases of liver	0.003	0.997	0.000
R73.9 Hyperglycaemia, unspecified	0.003	0.997	0.000
B25.8 Other cytomegaloviral diseases	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.003	0.997	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.997	0.003
M84.02 Malunion of fracture (Upper arm)	0.000	0.997	0.003
M84 Disorders of continuity of bone	0.000	0.997	0.003
B25.2 Cytomegaloviral pancreatitis	0.003	0.997	0.000
B25.1 Cytomegaloviral hepatitis	0.003	0.997	0.000
B25.0 Cytomegaloviral pneumonitis	0.003	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.000	0.997	0.003
M84.04 Malunion of fracture (Hand)	0.000	0.997	0.003
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.997	0.003
O36 Maternal care for other known or suspected foetal problems	0.000	0.997	0.003
H18.7 Other corneal deformities	0.000	0.997	0.003
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.003	0.997	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.997	0.003
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.003	0.997	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.003	0.997	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.003	0.997	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.003	0.997	0.000
M34.8 Other forms of systemic sclerosis	0.000	0.997	0.003
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.997	0.003
O36.8 Maternal care for other specified foetal problems	0.000	0.997	0.003
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.997	0.003
M84.09 Malunion of fracture (Site unspecified)	0.000	0.997	0.003
M84.08 Malunion of fracture (Other)	0.000	0.997	0.003
M84.00 Malunion of fracture (Multiple sites)	0.000	0.997	0.003
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.997	0.003
L60.8 Other nail disorders	0.000	0.997	0.003
N42.9 Disorder of prostate, unspecified	0.003	0.997	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.997	0.003
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.003	0.997	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.003	0.997	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.003	0.997	0.000
Q76.0 Spina bifida occulta	0.000	0.997	0.003
M00.9 Pyogenic arthritis, unspecified	0.003	0.997	0.000
N42.1 Congestion and haemorrhage of prostate	0.003	0.997	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.997	0.003
H18.3 Changes in corneal membranes	0.000	0.997	0.002
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
M46.9 Inflammatory spondylopathy, unspecified	0.003	0.997	0.000
C67 Malignant neoplasm of bladder	0.003	0.997	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
K35.2 Acute appendicitis with generalized peritonitis	0.003	0.997	0.000
O82.0 Delivery by elective Caesarean section	0.003	0.997	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.997	0.003
O36.1 Maternal care for other isoimmunisation	0.000	0.997	0.003
S92.4 Fracture of great toe	0.003	0.997	0.000
M84.06 Malunion of fracture (Lower leg)	0.000	0.997	0.002
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.997	0.003
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.997	0.003
S92.9 Fracture of foot, unspecified	0.002	0.997	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.002
M80 Osteoporosis with pathological fracture	0.000	0.997	0.002
K35.1 Acute appendicitis with peritoneal abscess	0.002	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.003	0.997	0.000
M84.9 Disorder of continuity of bone, unspecified	0.000	0.997	0.002
M84.3 Stress fracture, not elsewhere classified	0.000	0.997	0.002
M84.2 Delayed union of fracture	0.000	0.997	0.002
O36.9 Maternal care for foetal problem, unspecified	0.000	0.997	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
H18.1 Bullous keratopathy	0.000	0.998	0.002
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
M34.9 Systemic sclerosis, unspecified	0.000	0.998	0.002
M84.8 Other disorders of continuity of bone	0.000	0.998	0.002
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.998	0.002
O36.2 Maternal care for hydrops foetalis	0.000	0.998	0.002
K35 Acute appendicitis	0.002	0.998	0.000
S51.8 Open wound of other parts of forearm	0.002	0.998	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
C67.3 Anterior wall of bladder	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.002
O36.4 Maternal care for intra-uterine death	0.000	0.998	0.002
H65 Nonsuppurative otitis media	0.000	0.998	0.002
C67.5 Bladder neck	0.002	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M00.98 Pyogenic arthritis, unspecified (Other)	0.002	0.998	0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)	0.002	0.998	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.002	0.998	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.998	0.002
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.998	0.002
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
C67.0 Trigone of bladder	0.002	0.998	0.000
G00.1 Pneumococcal meningitis	0.002	0.998	0.000
M00 Pyogenic arthritis	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.000	0.998	0.002
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.002	0.998	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.002	0.998	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.002	0.998	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.002	0.998	0.000
C67.7 Urachus	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.998	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.002
C67.6 Ureteric orifice	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.000	0.998	0.002
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.000	0.998	0.002
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.002
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.002
H43 Disorders of vitreous body	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.998	0.002
M84.28 Delayed union of fracture (Other)	0.000	0.998	0.002
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.998	0.002
M84.26 Delayed union of fracture (Lower leg)	0.000	0.998	0.002
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.998	0.002
M84.24 Delayed union of fracture (Hand)	0.000	0.998	0.002
M84.23 Delayed union of fracture (Forearm)	0.000	0.998	0.002
M84.22 Delayed union of fracture (Upper arm)	0.000	0.998	0.002
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.998	0.002
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.998	0.002
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.998	0.002
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.998	0.002
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.998	0.002
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.998	0.002
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.998	0.002
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.998	0.002
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.998	0.002
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.998	0.002
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.998	0.002
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.998	0.002
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.998	0.002
M34 Systemic sclerosis	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.002
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M00.0 Staphylococcal arthritis and polyarthritis	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.998	0.002
M84.88 Other disorders of continuity of bone (Other)	0.000	0.998	0.002
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.998	0.002
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.998	0.002
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.998	0.002
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.998	0.002
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.998	0.002
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.998	0.002
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.998	0.002
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.998	0.002
T17.2 Foreign body in pharynx	0.000	0.998	0.002
K37 Unspecified appendicitis	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
C67.8 Overlapping lesion of bladder	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)	0.002	0.998	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
C97 Malignant neoplasms of independent (primary) multiple sites	0.000	0.998	0.002
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.000	0.998	0.002
M00.8 Arthritis and polyarthritis due to other specified bacterial agents	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
O36.6 Maternal care for excessive foetal growth	0.000	0.998	0.002
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
N92.3 Ovulation bleeding	0.002	0.998	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
K35-K38 Diseases of appendix	0.002	0.998	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.998	0.002
H65.2 Chronic serous otitis media	0.000	0.998	0.002
M00.2 Other streptococcal arthritis and polyarthritis	0.002	0.998	0.000
M00.1 Pneumococcal arthritis and polyarthritis	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.002	0.998	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
K40 Inguinal hernia	0.002	0.998	0.000
O82 Single delivery by Caesarean section	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.998	0.002
M83 Adult osteomalacia	0.000	0.998	0.002
M25.74 Osteophyte (Hand)	0.000	0.998	0.002
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
H43.3 Other vitreous opacities	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
Q76.9 Congenital malformation of bony thorax, unspecified	0.000	0.998	0.002
Q76.8 Other congenital malformations of bony thorax	0.000	0.998	0.002
Q76.7 Congenital malformation of sternum	0.000	0.998	0.002
Q76.6 Other congenital malformations of ribs	0.000	0.998	0.002
Q76.5 Cervical rib	0.000	0.998	0.002
Q76.3 Congenital scoliosis due to congenital bony malformation	0.000	0.998	0.002
Q76.2 Congenital spondylolisthesis	0.000	0.998	0.002
Q76.1 Klippel-Feil syndrome	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.002
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.998	0.002
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.998	0.002
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
H43.0 Vitreous prolapse	0.000	0.998	0.002
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)	0.002	0.998	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.998	0.002
M34.0 Progressive systemic sclerosis	0.000	0.998	0.002
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.998	0.002
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.998	0.002
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.998	0.002
N42 Other disorders of prostate	0.002	0.998	0.000
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)	0.002	0.998	0.000
M00.08 Staphylococcal arthritis and polyarthritis (Other)	0.002	0.998	0.000
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)	0.002	0.998	0.000
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)	0.002	0.998	0.000
M00.04 Staphylococcal arthritis and polyarthritis (Hand)	0.002	0.998	0.000
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)	0.002	0.998	0.000
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)	0.002	0.998	0.000
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)	0.002	0.998	0.000
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
K43 Ventral hernia	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.001	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
H43.2 Crystalline deposits in vitreous body	0.000	0.998	0.002
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.998	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.998	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.998	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.998	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.998	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.998	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.998	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.998	0.001
G70.0 Myasthenia gravis	0.002	0.998	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.998	0.002
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
K36 Other appendicitis	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
M00.89 Arthritis and polyarthritis due to other specified bacterial agents (Site unspecified)	0.001	0.998	0.000
M00.88 Arthritis and polyarthritis due to other specified bacterial agents (Other)	0.001	0.998	0.000
M00.87 Arthritis and polyarthritis due to other specified bacterial agents (Ankle and foot)	0.001	0.998	0.000
M00.85 Arthritis and polyarthritis due to other specified bacterial agents (Pelvic region and thigh)	0.001	0.998	0.000
M00.84 Arthritis and polyarthritis due to other specified bacterial agents (Hand)	0.001	0.998	0.000
M00.83 Arthritis and polyarthritis due to other specified bacterial agents (Forearm)	0.001	0.998	0.000
M00.82 Arthritis and polyarthritis due to other specified bacterial agents (Upper arm)	0.001	0.998	0.000
M00.81 Arthritis and polyarthritis due to other specified bacterial agents (Shoulder region)	0.001	0.998	0.000
M00.80 Arthritis and polyarthritis due to other specified bacterial agents (Multiple sites)	0.001	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
Y60.0 During surgical operation	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.001	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.000	0.998	0.002
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.998	0.002
M34.1 CR(E)ST syndrome	0.000	0.998	0.002
M00.19 Pneumococcal arthritis and polyarthritis (Site unspecified)	0.001	0.998	0.000
M00.18 Pneumococcal arthritis and polyarthritis (Other)	0.001	0.998	0.000
M00.17 Pneumococcal arthritis and polyarthritis (Ankle and foot)	0.001	0.998	0.000
M00.16 Pneumococcal arthritis and polyarthritis (Lower leg)	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations