TreeWAS – Variant ID: rs2101521

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H00.1 Chalazion	0.000	0.282	0.718
H00 Hordeolum and chalazion	0.000	0.375	0.625
E03.9 Hypothyroidism, unspecified	0.590	0.410	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.000	0.451	0.549
H04 Disorders of lachrymal system	0.000	0.479	0.521
H04.2 Epiphora	0.000	0.494	0.506
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.501	0.499
H01 Other inflammation of eyelid	0.000	0.510	0.490
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.532	0.468
H06.2 Dysthyroid exophthalmos	0.000	0.536	0.464
H01.8 Other specified inflammation of eyelid	0.000	0.566	0.434
H01.0 Blepharitis	0.000	0.575	0.425
H03 Disorders of eyelid in diseases classified elsewhere	0.000	0.589	0.411
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.592	0.408
H04.4 Chronic inflammation of lachrymal passages	0.000	0.598	0.402
H04.6 Other changes in lachrymal passages	0.000	0.626	0.374
H04.0 Dacryoadenitis	0.000	0.626	0.374
H04.8 Other disorders of lachrymal system	0.000	0.632	0.368
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.642	0.358
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.642	0.358
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.642	0.358
H01.1 Non-infectious dermatoses of eyelid	0.000	0.648	0.351
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.653	0.347
H04.9 Disorder of lachrymal system, unspecified	0.000	0.655	0.345
H04.1 Other disorders of lachrymal gland	0.000	0.686	0.314
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.000	0.688	0.312
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.000	0.705	0.294
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.000	0.705	0.294
H01.9 Inflammation of eyelid, unspecified	0.000	0.729	0.271
H05 Disorders of orbit	0.000	0.749	0.251
H05.9 Disorder of orbit, unspecified	0.000	0.813	0.187
H05.8 Other disorders of orbit	0.000	0.819	0.181
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.820	0.180
H05.4 Enophthalmos	0.000	0.820	0.180
H05.3 Deformity of orbit	0.000	0.820	0.180
H05.1 Chronic inflammatory disorders of orbit	0.000	0.820	0.180
E03 Other hypothyroidism	0.158	0.842	0.000
Z35.1 Supervision of pregnancy with history of abortive outcome	0.144	0.856	0.000
H02 Other disorders of eyelid	0.000	0.861	0.139
Z35 Supervision of high-risk pregnancy	0.137	0.863	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.131	0.869	0.000
H05.2 Exophthalmic conditions	0.000	0.873	0.127
H02.8 Other specified disorders of eyelid	0.000	0.874	0.126
Z35.0 Supervision of pregnancy with history of infertility	0.122	0.878	0.000
H02.2 Lagophthalmos	0.000	0.884	0.116
H05.0 Acute inflammation of orbit	0.000	0.886	0.114
E03.5 Myxoedema coma	0.113	0.886	0.000
E03.4 Atrophy of thyroid (acquired)	0.113	0.886	0.000
E03.3 Postinfectious hypothyroidism	0.113	0.886	0.000
E03.1 Congenital hypothyroidism without goitre	0.113	0.886	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.113	0.886	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.112	0.888	0.000
H02.5 Other disorders affecting eyelid function	0.000	0.890	0.110
Z35.8 Supervision of other high-risk pregnancies	0.107	0.893	0.000
H02.6 Xanthelasma of eyelid	0.000	0.898	0.102
Z35.5 Supervision of elderly primigravida	0.101	0.899	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.900	0.100
Z35.9 Supervision of high-risk pregnancy, unspecified	0.100	0.900	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.099	0.901	0.000
Z35.6 Supervision of very young primigravida	0.099	0.901	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.099	0.901	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.098	0.902	0.000
E03.8 Other specified hypothyroidism	0.089	0.911	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.923	0.077
H02.1 Ectropion of eyelid	0.000	0.933	0.067
H02.0 Entropion and trichiasis of eyelid	0.000	0.954	0.046
H02.4 Ptosis of eyelid	0.000	0.964	0.036
H02.3 Blepharochalasis	0.000	0.981	0.019
Z02.8 Other examinations for administrative purposes	0.000	0.982	0.018
O72.1 Other immediate postpartum haemorrhage	0.012	0.988	0.000
M75.0 Adhesive capsulitis of shoulder	0.010	0.990	0.000
F41.2 Mixed anxiety and depressive disorder	0.010	0.990	0.000
M75.5 Bursitis of shoulder	0.010	0.990	0.000
E00-E07 Disorders of thyroid gland	0.009	0.990	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.009	0.991	0.000
M75 Shoulder lesions	0.009	0.991	0.000
O63.1 Prolonged second stage (of labour)	0.009	0.991	0.000
O63 Long labour	0.009	0.991	0.000
O72 Postpartum haemorrhage	0.009	0.991	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.009	0.991	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.009	0.991	0.000
M75.4 Impingement syndrome of shoulder	0.008	0.992	0.000
J45.9 Asthma, unspecified	0.000	0.992	0.008
O60-O75 Complications of labour and delivery	0.008	0.992	0.000
M75.2 Bicipital tendinitis	0.008	0.992	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.008	0.992	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.992	0.008
O71 Other obstetric trauma	0.008	0.992	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.008	0.992	0.000
O64.1 Obstructed labour due to breech presentation	0.008	0.992	0.000
O63.0 Prolonged first stage (of labour)	0.008	0.992	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.008	0.992	0.000
Z02 Examination and encounter for administrative purposes	0.000	0.992	0.008
Z53.9 Procedure not carried out, unspecified reason	0.008	0.992	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.008	0.992	0.000
O66 Other obstructed labour	0.008	0.992	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.007	0.992	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.000	0.993	0.007
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.007	0.993	0.000
Z90.1 Acquired absence of breast(s)	0.007	0.993	0.000
O71.9 Obstetric trauma, unspecified	0.007	0.993	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.007	0.993	0.000
E00 Congenital iodine-deficiency syndrome	0.007	0.993	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.007	0.993	0.000
O71.4 Obstetric high vaginal laceration alone	0.007	0.993	0.000
O74 Complications of anaesthesia during labour and delivery	0.007	0.993	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.007	0.993	0.000
M75.8 Other shoulder lesions	0.007	0.993	0.000
D86.9 Sarcoidosis, unspecified	0.007	0.993	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.006	0.993	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.006	0.993	0.000
O72.3 Postpartum coagulation defects	0.006	0.993	0.000
E06 Thyroiditis	0.006	0.993	0.000
O64.5 Obstructed labour due to compound presentation	0.006	0.993	0.000
O64.4 Obstructed labour due to shoulder presentation	0.006	0.993	0.000
O64.3 Obstructed labour due to brow presentation	0.006	0.993	0.000
O64.2 Obstructed labour due to face presentation	0.006	0.993	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.006	0.994	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.006	0.994	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.006	0.994	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.006	0.994	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.006	0.994	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.006	0.994	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.006	0.994	0.000
M75.9 Shoulder lesion, unspecified	0.006	0.994	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.006	0.994	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.006	0.994	0.000
D86.0 Sarcoidosis of lung	0.006	0.994	0.000
O60 Preterm delivery	0.006	0.994	0.000
O71.5 Other obstetric injury to pelvic organs	0.006	0.994	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.006	0.994	0.000
O71.3 Obstetric laceration of cervix	0.006	0.994	0.000
O71.2 Postpartum inversion of uterus	0.006	0.994	0.000
O71.1 Rupture of uterus during labour	0.006	0.994	0.000
O71.0 Rupture of uterus before onset of labour	0.006	0.994	0.000
O61 Failed induction of labour	0.006	0.994	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.006	0.994	0.000
D86 Sarcoidosis	0.006	0.994	0.000
O71.8 Other specified obstetric trauma	0.006	0.994	0.000
Z02.9 Examination for administrative purposes, unspecified	0.000	0.994	0.006
Z02.7 Issue of medical certificate	0.000	0.994	0.006
Z02.6 Examination for insurance purposes	0.000	0.994	0.006
Z02.5 Examination for participation in sport	0.000	0.994	0.006
Z02.4 Examination for driving licence	0.000	0.994	0.006
Z02.3 Examination for recruitment to armed forces	0.000	0.994	0.006
Z02.2 Examination for admission to residential institution	0.000	0.994	0.006
Z02.1 Pre-employment examination	0.000	0.994	0.006
Z02.0 Examination for admission to educational institution	0.000	0.994	0.006
O73 Retained placenta and membranes, without haemorrhage	0.006	0.994	0.000
O36.6 Maternal care for excessive foetal growth	0.006	0.994	0.000
O66.9 Obstructed labour, unspecified	0.006	0.994	0.000
O66.8 Other specified obstructed labour	0.006	0.994	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.006	0.994	0.000
O66.2 Obstructed labour due to unusually large foetus	0.006	0.994	0.000
O66.1 Obstructed labour due to locked twins	0.006	0.994	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.005	0.994	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.005	0.994	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.005	0.994	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.005	0.994	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.005	0.994	0.000
O65.0 Obstructed labour due to deformed pelvis	0.005	0.994	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.006	0.994	0.000
O30.0 Twin pregnancy	0.006	0.994	0.000
N90.8 Other specified noninflammatory disorders of vulva and perineum	0.006	0.994	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.005	0.994	0.000
J45 Asthma	0.000	0.994	0.006
O69.8 Labour and delivery complicated by other cord complications	0.005	0.994	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
J45.0 Predominantly allergic asthma	0.000	0.995	0.005
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.005	0.995	0.000
O63.9 Long labour, unspecified	0.005	0.995	0.000
Z85.3 Personal history of malignant neoplasm of breast	0.005	0.995	0.000
O30 Multiple gestation	0.005	0.995	0.000
O62 Abnormalities of forces of labour	0.005	0.995	0.000
M75.3 Calcific tendinitis of shoulder	0.005	0.995	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.005	0.995	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.005	0.995	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.005	0.995	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.005	0.995	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.005	0.995	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.005	0.995	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.005	0.995	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.005	0.995	0.000
O36.9 Maternal care for foetal problem, unspecified	0.005	0.995	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.005	0.995	0.000
O66.4 Failed trial of labour, unspecified	0.005	0.995	0.000
O62.1 Secondary uterine inertia	0.005	0.995	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.005	0.995	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.005	0.995	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.005	0.995	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.005	0.995	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.005	0.995	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.005	0.995	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.005	0.995	0.000
O36 Maternal care for other known or suspected foetal problems	0.005	0.995	0.000
M75.81 Other shoulder lesions, right shoulder	0.005	0.995	0.000
O36.4 Maternal care for intra-uterine death	0.005	0.995	0.000
O40 Polyhydramnios	0.005	0.995	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.995	0.005
O71.7 Obstetric haematoma of pelvis	0.005	0.995	0.000
Z04.3 Examination and observation following other accident	0.000	0.995	0.005
E06.9 Thyroiditis, unspecified	0.005	0.995	0.000
O67.8 Other intrapartum haemorrhage	0.005	0.995	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.005	0.995	0.000
E06.5 Other chronic thyroiditis	0.005	0.995	0.000
E06.4 Drug-induced thyroiditis	0.005	0.995	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.005	0.995	0.000
E06.1 Subacute thyroiditis	0.005	0.995	0.000
E06.0 Acute thyroiditis	0.005	0.995	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.005	0.995	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.005	0.995	0.000
O69.3 Labour and delivery complicated by short cord	0.005	0.995	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.005	0.995	0.000
O62.9 Abnormality of forces of labour, unspecified	0.005	0.995	0.000
O60.3 Preterm delivery without spontaneous labour	0.005	0.995	0.000
O60.2 Preterm spontaneous labour with term delivery	0.005	0.995	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.005	0.995	0.000
O60.0 Preterm labour without delivery	0.005	0.995	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.005	0.995	0.000
O72.0 Third-stage haemorrhage	0.005	0.995	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.005	0.995	0.000
M19.98 Arthrosis, unspecified (Other)	0.005	0.995	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.005	0.995	0.000
O61.8 Other failed induction of labour	0.004	0.995	0.000
O61.1 Failed instrumental induction of labour	0.004	0.995	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.004	0.996	0.000
E07 Other disorders of thyroid	0.004	0.996	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.004	0.996	0.000
O61.9 Failed induction of labour, unspecified	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
O34.4 Maternal care for other abnormalities of cervix	0.004	0.996	0.000
C83.3 Large cell (diffuse)	0.000	0.996	0.004
J45.8 Mixed asthma	0.000	0.996	0.004
O32.2 Maternal care for transverse and oblique lie	0.004	0.996	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.004	0.996	0.000
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
E06.3 Autoimmune thyroiditis	0.004	0.996	0.000
O30.9 Multiple gestation, unspecified	0.004	0.996	0.000
O30.8 Other multiple gestation	0.004	0.996	0.000
O30.2 Quadruplet pregnancy	0.004	0.996	0.000
O30.1 Triplet pregnancy	0.004	0.996	0.000
O61.0 Failed medical induction of labour	0.004	0.996	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O62.8 Other abnormalities of forces of labour	0.004	0.996	0.000
E04 Other non-toxic goitre	0.004	0.996	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.004	0.996	0.000
O45 Premature separation of placenta [abruptio placentae]	0.004	0.996	0.000
O42 Premature rupture of membranes	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.004	0.996	0.000
R53 Malaise and fatigue	0.000	0.996	0.004
O34.3 Maternal care for cervical incompetence	0.004	0.996	0.000
H18.4 Corneal degeneration	0.000	0.996	0.004
J45.1 Nonallergic asthma	0.000	0.996	0.004
N41.0 Acute prostatitis	0.000	0.996	0.004
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.004	0.996	0.000
O36.2 Maternal care for hydrops foetalis	0.004	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
O36.1 Maternal care for other isoimmunisation	0.004	0.996	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.004	0.996	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.004	0.996	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.004	0.996	0.000
O33 Maternal care for known or suspected disproportion	0.004	0.996	0.000
N41 Inflammatory diseases of prostate	0.000	0.996	0.004
Y85.0 Sequelae of motor-vehicle accident	0.004	0.996	0.000
M19.9 Arthrosis, unspecified	0.004	0.996	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.004	0.996	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.004	0.996	0.000
O34.6 Maternal care for abnormality of vagina	0.004	0.996	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.004	0.996	0.000
O34.0 Maternal care for congenital malformation of uterus	0.004	0.996	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.004	0.996	0.000
O42.9 Premature rupture of membranes, unspecified	0.004	0.996	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.003	0.996	0.000
O34.1 Maternal care for tumour of corpus uteri	0.004	0.996	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.003	0.996	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.004	0.996	0.000
O73.0 Retained placenta, without haemorrhage	0.003	0.996	0.000
O32.6 Maternal care for compound presentation	0.003	0.997	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.003	0.997	0.000
E07.1 Dyshormogenetic goitre	0.003	0.997	0.000
E07.0 Hypersecretion of calcitonin	0.003	0.997	0.000
O32.4 Maternal care for high head at term	0.003	0.997	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.003	0.997	0.000
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.003	0.997	0.000
M19.94 Arthrosis, unspecified (Hand)	0.003	0.997	0.000
O32.3 Maternal care for face, brow and chin presentation	0.003	0.997	0.000
O62.3 Precipitate labour	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O70.2 Third degree perineal laceration during delivery	0.003	0.997	0.000
O31.8 Other complications specific to multiple gestation	0.003	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.997	0.000
O31.0 Papyraceous foetus	0.003	0.997	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
E04.8 Other specified non-toxic goitre	0.003	0.997	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.003	0.997	0.000
O45.8 Other premature separation of placenta	0.003	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O41 Other disorders of amniotic fluid and membranes	0.003	0.997	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O43 Placental disorders	0.003	0.997	0.000
O45.9 Premature separation of placenta, unspecified	0.003	0.997	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.003	0.997	0.000
E07.8 Other specified disorders of thyroid	0.003	0.997	0.000
O44 Placenta praevia	0.003	0.997	0.000
O32.0 Maternal care for unstable lie	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O62.2 Other uterine inertia	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.003	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.003	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.003	0.997	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.003	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.003	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.003	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.003	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.003	0.997	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
N41.8 Other inflammatory diseases of prostate	0.000	0.997	0.003
N41.3 Prostatocystitis	0.000	0.997	0.003
N41.2 Abscess of prostate	0.000	0.997	0.003
Z45.1 Adjustment and management of infusion pump	0.003	0.997	0.000
O32.8 Maternal care for other malpresentation of foetus	0.003	0.997	0.000
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
C83.0 Small cell (diffuse)	0.000	0.997	0.003
M19.92 Arthrosis, unspecified (Upper arm)	0.003	0.997	0.000
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
E05 Thyrotoxicosis [hyperthyroidism]	0.003	0.997	0.000
R41.3 Other amnesia	0.003	0.997	0.000
Z37.1 Single stillbirth	0.003	0.997	0.000
O70 Perineal laceration during delivery	0.003	0.997	0.000
O90 Complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
O43.9 Placental disorder, unspecified	0.003	0.997	0.000
O62.0 Primary inadequate contractions	0.002	0.997	0.001
O47 False labour	0.003	0.997	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.997	0.003
O33.9 Maternal care for disproportion, unspecified	0.002	0.997	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.002	0.997	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.002	0.997	0.000
O43.0 Placental transfusion syndromes	0.002	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.003	0.997	0.000
O43.2 Morbidly adherent placenta	0.002	0.997	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.997	0.002
O41.1 Infection of amniotic sac and membranes	0.002	0.997	0.000
R27.8 Other and unspecified lack of coordination	0.000	0.997	0.003
O85-O92 Complications predominantly related to the puerperium	0.002	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.997	0.000
N60.8 Other benign mammary dysplasias	0.003	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
O04.9 Complete or unspecified, without complication	0.002	0.998	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.002	0.998	0.000
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.998	0.002
C83.5 Lymphoblastic (diffuse)	0.000	0.998	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E05.5 Thyroid crisis or storm	0.002	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.002	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
Z37.2 Twins, both liveborn	0.002	0.998	0.000
C83.7 Burkitt's tumour	0.000	0.998	0.002
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.998	0.002
O75.3 Other infection during labour	0.002	0.998	0.000
O90.0 Disruption of Caesarean section wound	0.002	0.998	0.000
O91 Infections of breast associated with childbirth	0.002	0.998	0.000
O70.3 Fourth degree perineal laceration during delivery	0.002	0.998	0.000
O90.1 Disruption of perineal obstetric wound	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.002	0.998	0.000
K22.0 Achalasia of cardia	0.000	0.998	0.002
O90.9 Complication of the puerperium, unspecified	0.002	0.998	0.000
Z30.2 Sterilisation	0.000	0.998	0.002
O90.5 Postpartum thyroiditis	0.002	0.998	0.000
O90.4 Postpartum acute renal failure	0.002	0.998	0.000
O90.3 Cardiomyopathy in the puerperium	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E04.2 Non-toxic multinodular goitre	0.002	0.998	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.002	0.998	0.000
O46.9 Antepartum haemorrhage, unspecified	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.002	0.998	0.000
Y85 Sequelae of transport accidents	0.002	0.998	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.998	0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
O90.2 Haematoma of obstetric wound	0.002	0.998	0.000
O88 Obstetric embolism	0.002	0.998	0.000
O91.1 Abscess of breast associated with childbirth	0.002	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
O75.9 Complication of labour and delivery, unspecified	0.002	0.998	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.002	0.998	0.000
O75.4 Other complications of obstetric surgery and procedures	0.002	0.998	0.000
O75.1 Shock during or following labour and delivery	0.002	0.998	0.000
O47.9 False labour, unspecified	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
O04 Medical abortion	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.002	0.998	0.000
O89 Complications of anaesthesia during the puerperium	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.998	0.002
O92 Other disorders of breast and lactation associated with childbirth	0.002	0.998	0.000
Z37 Outcome of delivery	0.002	0.998	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.002	0.998	0.000
O91.0 Infection of nipple associated with childbirth	0.002	0.998	0.000
K41 Femoral hernia	0.002	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
O00-O08 Pregnancy with abortive outcome	0.002	0.998	0.000
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
O43.8 Other placental disorders	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
O85 Puerperal sepsis	0.002	0.998	0.000
W25.9 Unspecified place	0.000	0.998	0.002
H81.1 Benign paroxysmal vertigo	0.000	0.998	0.002
M79.54 Residual foreign body in soft tissue (Hand)	0.002	0.998	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.002	0.998	0.000
E61.1 Iron deficiency	0.000	0.998	0.002
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
O87 Venous complications in the puerperium	0.002	0.998	0.000
O04.4 Incomplete, without complication	0.002	0.998	0.000
O88.8 Other obstetric embolism	0.001	0.998	0.000
O88.3 Obstetric pyaemic and septic embolism	0.001	0.998	0.000
O88.2 Obstetric blood-clot embolism	0.001	0.998	0.000
O88.1 Amniotic fluid embolism	0.001	0.998	0.000
O88.0 Obstetric air embolism	0.001	0.998	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.002	0.998	0.000
O47.0 False labour before 37 completed weeks of gestation	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
O04.8 Complete or unspecified, with other and unspecified complications	0.002	0.998	0.000
O04.7 Complete or unspecified, complicated by embolism	0.002	0.998	0.000
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O04.3 Incomplete, with other and unspecified complications	0.002	0.998	0.000
O04.2 Incomplete, complicated by embolism	0.002	0.998	0.000
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.002	0.998	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.001	0.998	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.001	0.998	0.000
O89.6 Failed or difficult intubation during the puerperium	0.001	0.998	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.001	0.998	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.001	0.998	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.001	0.998	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.001	0.998	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.001	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
E87.2 Acidosis	0.000	0.998	0.002
O08 Complications following abortion and ectopic and molar pregnancy	0.002	0.998	0.000
O92.7 Other and unspecified disorders of lactation	0.001	0.998	0.000
O92.6 Galactorrhoea	0.001	0.998	0.000
O92.5 Suppressed lactation	0.001	0.998	0.000
O92.4 Hypogalactia	0.001	0.998	0.000
O92.3 Agalactia	0.001	0.998	0.000
O92.0 Retracted nipple associated with childbirth	0.001	0.998	0.000
D83 Common variable immunodeficiency	0.001	0.998	0.000
F41 Other anxiety disorders	0.002	0.998	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.002	0.998	0.000
O75.8 Other specified complications of labour and delivery	0.002	0.998	0.000
Z37.9 Outcome of delivery unspecified	0.002	0.998	0.000
Z37.7 Other multiple births, all stillborn	0.002	0.998	0.000
Z37.6 Other multiple births, some liveborn	0.002	0.998	0.000
Z37.5 Other multiple births, all liveborn	0.002	0.998	0.000
Z37.4 Twins, both stillborn	0.002	0.998	0.000
M13.90 Arthritis, unspecified (Multiple sites)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations