TreeWAS – Variant ID: rs2163950

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O48 Prolonged pregnancy	0.028	0.972	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.017	0.983	0.000
O47 False labour	0.016	0.984	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.014	0.986	0.000
O47.0 False labour before 37 completed weeks of gestation	0.014	0.986	0.000
O45 Premature separation of placenta [abruptio placentae]	0.014	0.986	0.000
O30 Multiple gestation	0.014	0.986	0.000
O40 Polyhydramnios	0.013	0.987	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.013	0.987	0.000
O43 Placental disorders	0.012	0.988	0.000
O33 Maternal care for known or suspected disproportion	0.012	0.988	0.000
O31 Complications specific to multiple gestation	0.012	0.988	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.012	0.988	0.000
O44 Placenta praevia	0.012	0.988	0.000
O47.9 False labour, unspecified	0.012	0.988	0.000
O45.9 Premature separation of placenta, unspecified	0.011	0.988	0.000
O30.0 Twin pregnancy	0.011	0.989	0.000
O36 Maternal care for other known or suspected foetal problems	0.011	0.989	0.000
O41 Other disorders of amniotic fluid and membranes	0.011	0.989	0.000
O36.9 Maternal care for foetal problem, unspecified	0.010	0.990	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.010	0.990	0.000
O34.3 Maternal care for cervical incompetence	0.010	0.990	0.000
O34.1 Maternal care for tumour of corpus uteri	0.010	0.990	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.010	0.990	0.000
O45.8 Other premature separation of placenta	0.010	0.990	0.000
O45.0 Premature separation of placenta with coagulation defect	0.010	0.990	0.000
O30.9 Multiple gestation, unspecified	0.010	0.990	0.000
O30.8 Other multiple gestation	0.010	0.990	0.000
O30.2 Quadruplet pregnancy	0.010	0.990	0.000
O30.1 Triplet pregnancy	0.010	0.990	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.010	0.990	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.010	0.990	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.009	0.990	0.000
O34.6 Maternal care for abnormality of vagina	0.009	0.990	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.009	0.990	0.000
O34.4 Maternal care for other abnormalities of cervix	0.009	0.990	0.000
O34.0 Maternal care for congenital malformation of uterus	0.009	0.990	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.009	0.991	0.000
F60.3 Emotionally unstable personality disorder	0.009	0.991	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.009	0.991	0.000
O43.1 Malformation of placenta	0.009	0.991	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.009	0.991	0.000
O43.9 Placental disorder, unspecified	0.009	0.991	0.000
O43.2 Morbidly adherent placenta	0.009	0.991	0.000
O43.0 Placental transfusion syndromes	0.009	0.991	0.000
O31.8 Other complications specific to multiple gestation	0.009	0.991	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.009	0.991	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.009	0.991	0.000
O31.0 Papyraceous foetus	0.009	0.991	0.000
O33.9 Maternal care for disproportion, unspecified	0.009	0.991	0.000
O33.8 Maternal care for disproportion of other origin	0.009	0.991	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.009	0.991	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.009	0.991	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.009	0.991	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.009	0.991	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.009	0.991	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.009	0.991	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.009	0.991	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.009	0.991	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.009	0.991	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.009	0.991	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.009	0.991	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.009	0.991	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.009	0.991	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.009	0.991	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.009	0.991	0.000
O43.8 Other placental disorders	0.009	0.991	0.000
F60 Specific personality disorders	0.009	0.991	0.000
O36.4 Maternal care for intra-uterine death	0.009	0.991	0.000
O42 Premature rupture of membranes	0.009	0.991	0.000
F60-F69 Disorders of adult personality and behaviour	0.009	0.991	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.009	0.991	0.000
F02 Dementia in other diseases classified elsewhere	0.009	0.991	0.000
O36.8 Maternal care for other specified foetal problems	0.009	0.991	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.008	0.992	0.000
O44.1 Placenta praevia with haemorrhage	0.008	0.992	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.008	0.992	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.008	0.992	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.008	0.992	0.000
O36.2 Maternal care for hydrops foetalis	0.008	0.992	0.000
O36.1 Maternal care for other isoimmunisation	0.008	0.992	0.000
Chapter V Mental and behavioural disorders	0.008	0.992	0.000
F05.9 Delirium, unspecified	0.008	0.992	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.008	0.992	0.000
O41.1 Infection of amniotic sac and membranes	0.008	0.992	0.000
F00 Dementia in Alzheimer's disease	0.008	0.992	0.000
O41.0 Oligohydramnios	0.008	0.992	0.000
O46.8 Other antepartum haemorrhage	0.007	0.992	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.007	0.992	0.000
F30-F39 Mood [affective] disorders	0.008	0.992	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.008	0.992	0.000
O36.5 Maternal care for poor foetal growth	0.007	0.992	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.007	0.992	0.000
F64 Gender identity disorders	0.007	0.993	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.007	0.993	0.000
Y52 Agents primarily affecting the cardiovascular system	0.007	0.993	0.000
O32.3 Maternal care for face, brow and chin presentation	0.007	0.993	0.000
F01 Vascular dementia	0.007	0.993	0.000
F99-F99 Unspecified mental disorder	0.007	0.993	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.007	0.993	0.000
F02.3 Dementia in Parkinson's disease	0.007	0.993	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.007	0.993	0.000
F80-F89 Disorders of psychological development	0.007	0.993	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.007	0.993	0.000
O32.6 Maternal care for compound presentation	0.007	0.993	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.007	0.993	0.000
O32.4 Maternal care for high head at term	0.007	0.993	0.000
F32 Depressive episode	0.007	0.993	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.007	0.993	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.007	0.993	0.000
F09 Unspecified organic or symptomatic mental disorder	0.007	0.993	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.007	0.993	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.007	0.993	0.000
O42.9 Premature rupture of membranes, unspecified	0.007	0.993	0.000
F60.8 Other specific personality disorders	0.006	0.993	0.000
F60.7 Dependent personality disorder	0.006	0.993	0.000
F60.6 Anxious [avoidant] personality disorder	0.006	0.993	0.000
F60.5 Anankastic personality disorder	0.006	0.993	0.000
F60.4 Histrionic personality disorder	0.006	0.993	0.000
F60.2 Dissocial personality disorder	0.006	0.993	0.000
F60.1 Schizoid personality disorder	0.006	0.993	0.000
F60.0 Paranoid personality disorder	0.006	0.993	0.000
F99 Mental disorder, not otherwise specified	0.007	0.993	0.000
O32.8 Maternal care for other malpresentation of foetus	0.006	0.993	0.000
F31 Bipolar affective disorder	0.007	0.993	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.006	0.993	0.000
O32.2 Maternal care for transverse and oblique lie	0.006	0.993	0.000
F68 Other disorders of adult personality and behaviour	0.006	0.993	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.006	0.993	0.000
F65 Disorders of sexual preference	0.006	0.993	0.000
F63 Habit and impulse disorders	0.006	0.993	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.006	0.993	0.000
F69 Unspecified disorder of adult personality and behaviour	0.006	0.993	0.000
F61 Mixed and other personality disorders	0.006	0.993	0.000
F64.0 Transsexualism	0.006	0.993	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.006	0.993	0.000
F60.9 Personality disorder, unspecified	0.006	0.993	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.007	0.993	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.006	0.994	0.000
F02.2 Dementia in Huntington's disease	0.006	0.994	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.006	0.994	0.000
F02.0 Dementia in Pick's disease	0.006	0.994	0.000
F05.8 Other delirium	0.006	0.994	0.000
F05.1 Delirium superimposed on dementia	0.006	0.994	0.000
F05.0 Delirium not superimposed on dementia, so described	0.006	0.994	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
F34 Persistent mood [affective] disorders	0.006	0.994	0.000
Y40.0 Penicillins	0.006	0.994	0.000
O32.1 Maternal care for breech presentation	0.006	0.994	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.006	0.994	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.006	0.994	0.000
F70-F79 Mental retardation	0.006	0.994	0.000
F03 Unspecified dementia	0.006	0.994	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.006	0.994	0.000
Y40 Systemic antibiotics	0.006	0.994	0.000
F32.0 Mild depressive episode	0.006	0.994	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.006	0.994	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.006	0.994	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.006	0.994	0.000
F84 Pervasive developmental disorders	0.006	0.994	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.006	0.994	0.000
Z13.9 Special screening examination, unspecified	0.006	0.994	0.000
F01.9 Vascular dementia, unspecified	0.006	0.994	0.000
F39 Unspecified mood [affective] disorder	0.006	0.994	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
F38 Other mood [affective] disorders	0.006	0.994	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.006	0.994	0.000
M20.5 Other deformities of toe(s) (acquired)	0.000	0.994	0.006
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.006	0.994	0.000
O46.9 Antepartum haemorrhage, unspecified	0.006	0.994	0.000
O32.0 Maternal care for unstable lie	0.005	0.994	0.000
F64.9 Gender identity disorder, unspecified	0.005	0.994	0.000
F64.8 Other gender identity disorders	0.005	0.994	0.000
F64.2 Gender identity disorder of childhood	0.005	0.994	0.000
F64.1 Dual-role transvestism	0.005	0.994	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.994	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.005	0.994	0.000
Y52.7 Peripheral vasodilators	0.005	0.994	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.994	0.000
F81 Specific developmental disorders of scholastic skills	0.005	0.994	0.000
F01.8 Other vascular dementia	0.005	0.994	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.005	0.994	0.000
F01.2 Subcortical vascular dementia	0.005	0.994	0.000
F01.1 Multi-infarct dementia	0.005	0.994	0.000
F01.0 Vascular dementia of acute onset	0.005	0.994	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.005	0.994	0.000
F34.1 Dysthymia	0.005	0.994	0.000
Y58 Bacterial vaccines	0.005	0.994	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
F84.5 Asperger's syndrome	0.005	0.995	0.000
F80 Specific developmental disorders of speech and language	0.005	0.995	0.000
F89 Unspecified disorder of psychological development	0.005	0.995	0.000
F88 Other disorders of psychological development	0.005	0.995	0.000
F83 Mixed specific developmental disorders	0.005	0.995	0.000
F82 Specific developmental disorder of motor function	0.005	0.995	0.000
F32.8 Other depressive episodes	0.005	0.995	0.000
Y48 Anaesthetics and therapeutic gases	0.005	0.995	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
Y52.1 Calcium-channel blockers	0.005	0.995	0.000
O36.6 Maternal care for excessive foetal growth	0.005	0.995	0.000
S02.60 Fracture of mandible (closed)	0.005	0.995	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.005	0.995	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.005	0.995	0.000
F07.2 Postconcussional syndrome	0.005	0.995	0.000
F07.1 Postencephalitic syndrome	0.005	0.995	0.000
F07.0 Organic personality disorder	0.005	0.995	0.000
F32.3 Severe depressive episode with psychotic symptoms	0.005	0.995	0.000
F30 Manic episode	0.005	0.995	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.005	0.995	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.005	0.995	0.000
Y57 Other and unspecified drugs and medicaments	0.005	0.995	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.005	0.995	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.005	0.995	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.005	0.995	0.000
F06.5 Organic dissociative disorder	0.005	0.995	0.000
F06.4 Organic anxiety disorder	0.005	0.995	0.000
F06.3 Organic mood [affective] disorders	0.005	0.995	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.005	0.995	0.000
F06.1 Organic catatonic disorder	0.005	0.995	0.000
F06.0 Organic hallucinosis	0.005	0.995	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.005	0.995	0.000
F31.8 Other bipolar affective disorders	0.005	0.995	0.000
F31.7 Bipolar affective disorder, currently in remission	0.005	0.995	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.005	0.995	0.000
S02.20 Fracture of nasal bones (closed)	0.005	0.995	0.000
V23.4 Driver injured in traffic accident	0.005	0.995	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.005	0.995	0.000
F32.9 Depressive episode, unspecified	0.005	0.995	0.000
F62.9 Enduring personality change, unspecified	0.005	0.995	0.000
F62.8 Other enduring personality changes	0.005	0.995	0.000
F62.1 Enduring personality change after psychiatric illness	0.005	0.995	0.000
F62.0 Enduring personality change after catastrophic experience	0.005	0.995	0.000
F63.9 Habit and impulse disorder, unspecified	0.005	0.995	0.000
F63.8 Other habit and impulse disorders	0.005	0.995	0.000
F63.3 Trichotillomania	0.005	0.995	0.000
F63.2 Pathological stealing [kleptomania]	0.005	0.995	0.000
F63.1 Pathological fire-setting [pyromania]	0.005	0.995	0.000
F63.0 Pathological gambling	0.005	0.995	0.000
F65.9 Disorder of sexual preference, unspecified	0.005	0.995	0.000
F65.8 Other disorders of sexual preference	0.005	0.995	0.000
F65.6 Multiple disorders of sexual preference	0.005	0.995	0.000
F65.5 Sadomasochism	0.005	0.995	0.000
F65.4 Paedophilia	0.005	0.995	0.000
F65.3 Voyeurism	0.005	0.995	0.000
F65.2 Exhibitionism	0.005	0.995	0.000
F65.1 Fetishistic transvestism	0.005	0.995	0.000
F65.0 Fetishism	0.005	0.995	0.000
F66.9 Psychosexual development disorder, unspecified	0.005	0.995	0.000
F66.8 Other psychosexual development disorders	0.005	0.995	0.000
F66.2 Sexual relationship disorder	0.005	0.995	0.000
F66.1 Egodystonic sexual orientation	0.005	0.995	0.000
F66.0 Sexual maturation disorder	0.005	0.995	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.005	0.995	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.005	0.995	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.005	0.995	0.000
Y59 Other and unspecified vaccines and biological substances	0.005	0.995	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.005	0.995	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.005	0.995	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.005	0.995	0.000
F06.7 Mild cognitive disorder	0.005	0.995	0.000
M20 Acquired deformities of fingers and toes	0.000	0.995	0.005
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.005	0.995	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.005	0.995	0.000
F34.8 Other persistent mood [affective] disorders	0.005	0.995	0.000
F34.0 Cyclothymia	0.005	0.995	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
F29 Unspecified nonorganic psychosis	0.005	0.995	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.005	0.995	0.000
Y58.0 BCG vaccine	0.005	0.995	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.005	0.995	0.000
Y40.3 Macrolides	0.005	0.995	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.005	0.995	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.005	0.995	0.000
J69.0 Pneumonitis due to food and vomit	0.005	0.995	0.000
F79 Unspecified mental retardation	0.005	0.995	0.000
F78 Other mental retardation	0.005	0.995	0.000
F73 Profound mental retardation	0.005	0.995	0.000
F72 Severe mental retardation	0.005	0.995	0.000
F71 Moderate mental retardation	0.005	0.995	0.000
F70 Mild mental retardation	0.005	0.995	0.000
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.005	0.995	0.000
F95 Tic disorders	0.005	0.995	0.000
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.005	0.995	0.000
F93 Emotional disorders with onset specific to childhood	0.005	0.995	0.000
F92 Mixed disorders of conduct and emotions	0.005	0.995	0.000
F91 Conduct disorders	0.005	0.995	0.000
F90 Hyperkinetic disorders	0.005	0.995	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.005	0.995	0.000
Chapter XX External causes of morbidity and mortality	0.005	0.995	0.000
X60-X84 Intentional self-harm	0.005	0.995	0.000
S02.6 Fracture of mandible	0.005	0.995	0.000
Y40.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
Y40.6 Rifamycins	0.005	0.995	0.000
Y40.5 Aminoglycosides	0.005	0.995	0.000
Y40.4 Tetracyclines	0.005	0.995	0.000
Y40.2 Chloramphenicol group	0.005	0.995	0.000
V20-V29 Motorcycle rider injured in transport accident	0.005	0.995	0.000
M20.2 Hallux rigidus	0.000	0.995	0.005
F84.9 Pervasive developmental disorder, unspecified	0.004	0.995	0.000
F84.8 Other pervasive developmental disorders	0.004	0.995	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.004	0.995	0.000
F84.3 Other childhood disintegrative disorder	0.004	0.995	0.000
F84.2 Rett's syndrome	0.004	0.995	0.000
F84.1 Atypical autism	0.004	0.995	0.000
F84.0 Childhood autism	0.004	0.995	0.000
S02.2 Fracture of nasal bones	0.005	0.995	0.000
F31.9 Bipolar affective disorder, unspecified	0.005	0.995	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.005	0.995	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.004	0.995	0.000
Y44 Agents primarily affecting blood constituents	0.004	0.995	0.000
T42.4 Benzodiazepines	0.005	0.995	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.004	0.995	0.000
F43 Reaction to severe stress, and adjustment disorders	0.005	0.995	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.004	0.995	0.000
X62.9 Unspecified place	0.005	0.995	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.995	0.000
Y43 Primarily systemic agents	0.005	0.995	0.000
F10.2 Dependence syndrome	0.005	0.995	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.004	0.995	0.000
M20.1 Hallux valgus (acquired)	0.000	0.995	0.005
Y53.4 Other laxatives	0.004	0.996	0.000
W03.9 Unspecified place	0.004	0.996	0.000
F33 Recurrent depressive disorder	0.004	0.996	0.000
F50 Eating disorders	0.004	0.996	0.000
F38.8 Other specified mood [affective] disorders	0.004	0.996	0.000
F38.1 Other recurrent mood [affective] disorders	0.004	0.996	0.000
F38.0 Other single mood [affective] disorders	0.004	0.996	0.000
Y48.3 Local anaesthetics	0.004	0.996	0.000
S02 Fracture of skull and facial bones	0.004	0.996	0.000
Y40.8 Other systemic antibiotics	0.004	0.996	0.000
W10.8 Other specified place	0.004	0.996	0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.004	0.996	0.000
F51 Nonorganic sleep disorders	0.004	0.996	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.004	0.996	0.000
F55 Abuse of non-dependence-producing substances	0.004	0.996	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.004	0.996	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.004	0.996	0.000
Y40.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
F81.8 Other developmental disorders of scholastic skills	0.004	0.996	0.000
F81.3 Mixed disorder of scholastic skills	0.004	0.996	0.000
F81.2 Specific disorder of arithmetical skills	0.004	0.996	0.000
F81.1 Specific spelling disorder	0.004	0.996	0.000
F81.0 Specific reading disorder	0.004	0.996	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.004	0.996	0.000
F10.9 Unspecified mental and behavioural disorder	0.004	0.996	0.000
M20.3 Other deformity of hallux (acquired)	0.000	0.996	0.004
F28 Other nonorganic psychotic disorders	0.004	0.996	0.000
F24 Induced delusional disorder	0.004	0.996	0.000
F21 Schizotypal disorder	0.004	0.996	0.000
Y57.8 Other drugs and medicaments	0.004	0.996	0.000
Y58.9 Other and unspecified bacterial vaccines	0.004	0.996	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.004	0.996	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.004	0.996	0.000
Y58.5 Diphtheria vaccine	0.004	0.996	0.000
Y58.4 Tetanus vaccine	0.004	0.996	0.000
Y58.3 Plague vaccine	0.004	0.996	0.000
Y58.2 Cholera vaccine	0.004	0.996	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.004	0.996	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
Y53.7 Emetics	0.004	0.996	0.000
Y53.6 Antidiarrhoeal drugs	0.004	0.996	0.000
Y53.5 Digestants	0.004	0.996	0.000
Y53.3 Saline and osmotic laxatives	0.004	0.996	0.000
Y53.2 Stimulant laxatives	0.004	0.996	0.000
Y53.0 Histamine H2-receptor antagonists	0.004	0.996	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.004	0.996	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.004	0.996	0.000
F80.8 Other developmental disorders of speech and language	0.004	0.996	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.004	0.996	0.000
F80.2 Receptive language disorder	0.004	0.996	0.000
F80.1 Expressive language disorder	0.004	0.996	0.000
F80.0 Specific speech articulation disorder	0.004	0.996	0.000
F25 Schizoaffective disorders	0.004	0.996	0.000
W10 Fall on and from stairs and steps	0.004	0.996	0.000
W75-W84 Other accidental threats to breathing	0.004	0.996	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.996	0.004
M20.4 Other hammer toe(s) (acquired)	0.000	0.996	0.004
Y57.9 Drug or medicament, unspecified	0.004	0.996	0.000
Y48.5 Therapeutic gases	0.004	0.996	0.000
Y48.4 Anaesthetic, unspecified	0.004	0.996	0.000
Y48.2 Other and unspecified general anaesthetics	0.004	0.996	0.000
Y48.1 Parenteral anaesthetics	0.004	0.996	0.000
Y48.0 Inhaled anaesthetics	0.004	0.996	0.000
F32.1 Moderate depressive episode	0.004	0.996	0.000
Z91.5 Personal history of self-harm	0.004	0.996	0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.004	0.996	0.000
F43.1 Posttraumatic stress disorder	0.004	0.996	0.000
F45 Somatoform disorders	0.004	0.996	0.000
F22 Persistent delusional disorders	0.004	0.996	0.000
X10-X19 Contact with heat and hot substances	0.004	0.996	0.000
F30.8 Other manic episodes	0.004	0.996	0.000
F30.2 Mania with psychotic symptoms	0.004	0.996	0.000
F30.1 Mania without psychotic symptoms	0.004	0.996	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
F48 Other neurotic disorders	0.004	0.996	0.000
F44 Dissociative [conversion] disorders	0.004	0.996	0.000
Y57.7 Vitamins, not elsewhere classified	0.004	0.996	0.000
Y57.6 Other diagnostic agents	0.004	0.996	0.000
Y57.4 Pharmaceutical excipients	0.004	0.996	0.000
Y57.3 Alcohol deterrents	0.004	0.996	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
Y57.1 Lipotropic drugs	0.004	0.996	0.000
Y57.0 Appetite depressants [anorectics]	0.004	0.996	0.000
W00-W19 Falls	0.004	0.996	0.000
Y00-Y09 Assault	0.004	0.996	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.004	0.996	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.004	0.996	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.004	0.996	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.004	0.996	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.004	0.996	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.004	0.996	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.004	0.996	0.000
S02.0 Fracture of vault of skull	0.004	0.996	0.000
X68 Intentional self-poisoning by and exposure to pesticides	0.004	0.996	0.000
V40-V49 Car occupant injured in transport accident	0.004	0.996	0.000
F43.9 Reaction to severe stress, unspecified	0.004	0.996	0.000
Y45.5 4-Aminophenol derivatives	0.004	0.996	0.000
Y54.5 Other diuretics	0.004	0.996	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.004	0.996	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
F10.4 Withdrawal state with delirium	0.004	0.996	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.996	0.004
X40-X49 Accidental poisoning by and exposure to noxious substances	0.004	0.996	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.004	0.996	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.004	0.996	0.000
F43.2 Adjustment disorders	0.004	0.996	0.000
Y46.8 Antispasticity drugs	0.004	0.996	0.000
Y46.7 Anti-Parkinsonism drugs	0.004	0.996	0.000
Y46.6 Other and unspecified antiepileptics	0.004	0.996	0.000
Y46.5 Valproic acid	0.004	0.996	0.000
Y46.4 Iminostilbenes	0.004	0.996	0.000
Y46.3 Deoxybarbiturates	0.004	0.996	0.000
Y46.2 Hydantoin derivatives	0.004	0.996	0.000
Y46.1 Oxazolidinediones	0.004	0.996	0.000
Y46.0 Succinimides	0.004	0.996	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.004	0.996	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.004	0.996	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.004	0.996	0.000
Y47.4 Bromine compounds	0.004	0.996	0.000
Y47.3 Paraldehyde	0.004	0.996	0.000
Y47.2 Chloral derivatives	0.004	0.996	0.000
Y47.1 Benzodiazepines	0.004	0.996	0.000
Y47.0 Barbiturates, not elsewhere classified	0.004	0.996	0.000
Y50.9 Central nervous system stimulant, unspecified	0.004	0.996	0.000
Y50.8 Other central nervous system stimulants	0.004	0.996	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.004	0.996	0.000
Y50.1 Opioid receptor antagonists	0.004	0.996	0.000
Y50.0 Analeptics	0.004	0.996	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.004	0.996	0.000
Y55.5 Anticommon cold drugs	0.004	0.996	0.000
Y55.4 Expectorants	0.004	0.996	0.000
Y55.3 Antitussives	0.004	0.996	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
Y55.0 Oxytocic drugs	0.004	0.996	0.000
Y59.9 Vaccine or biological substance, unspecified	0.004	0.996	0.000
Y59.8 Other specified vaccines and biological substances	0.004	0.996	0.000
Y59.3 Immunoglobulin	0.004	0.996	0.000
Y59.2 Protozoal vaccines	0.004	0.996	0.000
Y59.1 Rickettsial vaccines	0.004	0.996	0.000
Y59.0 Viral vaccines	0.004	0.996	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.004	0.996	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.004	0.996	0.000
F23 Acute and transient psychotic disorders	0.004	0.996	0.000
Y57.5 X-ray contrast media	0.004	0.996	0.000
F42 Obsessive-compulsive disorder	0.004	0.996	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.004	0.996	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
Y41.5 Antiviral drugs	0.004	0.996	0.000
Y41.4 Anthelminthics	0.004	0.996	0.000
Y41.3 Other antiprotozoal drugs	0.004	0.996	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
Y41.1 Antimycobacterial drugs	0.004	0.996	0.000
Y41.0 Sulphonamides	0.004	0.996	0.000
Y42.9 Other and unspecified hormone antagonists	0.004	0.996	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.004	0.996	0.000
Y42.4 Oral contraceptives	0.004	0.996	0.000
Y42.2 Antithyroid drugs	0.004	0.996	0.000
Y42.1 Thyroid hormones and substitutes	0.004	0.996	0.000
F11 Mental and behavioural disorders due to use of opioids	0.004	0.996	0.000
V10-V19 Pedal cyclist injured in transport accident	0.004	0.996	0.000
S02.4 Fracture of malar and maxillary bones	0.004	0.996	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.004	0.996	0.000
Y45.8 Other analgesics and antipyretics	0.004	0.996	0.000
Y45.4 Antirheumatics	0.004	0.996	0.000
Y54.9 Mineral salts, not elsewhere classified	0.004	0.996	0.000
Y54.8 Agents affecting uric acid metabolism	0.004	0.996	0.000
Y54.7 Agents affecting calcification	0.004	0.996	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
Y54.4 Loop [high-ceiling] diuretics	0.004	0.996	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.004	0.996	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.004	0.996	0.000
Y54.0 Mineralocorticoids	0.004	0.996	0.000
F30.9 Manic episode, unspecified	0.003	0.996	0.000
S02.3 Fracture of orbital floor	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations