TreeWAS – Variant ID: rs2216405

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N39.3 Stress incontinence	0.137	0.863	0.000
N39.4 Other specified urinary incontinence	0.134	0.866	0.000
Z95.4 Presence of other heart-valve replacement	0.000	0.873	0.127
N39 Other disorders of urinary system	0.125	0.875	0.000
Z95 Presence of cardiac and vascular implants and grafts	0.000	0.877	0.123
Z95.2 Presence of prosthetic heart valve	0.000	0.879	0.121
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.885	0.115
N93.8 Other specified abnormal uterine and vaginal bleeding	0.111	0.889	0.000
Z95.8 Presence of other cardiac and vascular implants and grafts	0.000	0.898	0.102
Z95.0 Presence of cardiac pacemaker	0.000	0.900	0.100
N30-N39 Other diseases of urinary system	0.090	0.910	0.000
N39.1 Persistent proteinuria, unspecified	0.090	0.910	0.000
N39.2 Orthostatic proteinuria, unspecified	0.090	0.910	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.089	0.911	0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.087	0.913	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.077	0.923	0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified	0.000	0.923	0.077
N34 Urethritis and urethral syndrome	0.076	0.924	0.000
N39.8 Other specified disorders of urinary system	0.074	0.926	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.073	0.927	0.000
Z95.3 Presence of xenogenic heart valve	0.000	0.928	0.072
N36 Other disorders of urethra	0.067	0.932	0.000
N37 Urethral disorders in diseases classified elsewhere	0.065	0.935	0.000
N33 Bladder disorders in diseases classified elsewhere	0.065	0.935	0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.064	0.936	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.064	0.936	0.000
D51 Vitamin B12 deficiency anaemia	0.064	0.936	0.000
N34.2 Other urethritis	0.063	0.937	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.937	0.063
Z95.1 Presence of aortocoronary bypass graft	0.000	0.937	0.063
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.061	0.939	0.000
N35 Urethral stricture	0.060	0.940	0.000
N36.9 Urethral disorder, unspecified	0.060	0.940	0.000
N30 Cystitis	0.060	0.940	0.000
N34.3 Urethral syndrome, unspecified	0.058	0.942	0.000
S09.9 Unspecified injury of head	0.000	0.944	0.056
N34.1 Nonspecific urethritis	0.054	0.945	0.000
N34.0 Urethral abscess	0.054	0.945	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.055	0.945	0.000
N35.8 Other urethral stricture	0.052	0.948	0.000
N36.2 Urethral caruncle	0.051	0.949	0.000
N30.2 Other chronic cystitis	0.050	0.950	0.000
N30.1 Interstitial cystitis (chronic)	0.048	0.952	0.000
N33.8 Bladder disorders in other diseases classified elsewhere	0.047	0.953	0.000
N33.0 Tuberculous cystitis	0.047	0.953	0.000
N37.8 Other urethral disorders in diseases classified elsewhere	0.047	0.953	0.000
N37.0 Urethritis in diseases classified elsewhere	0.047	0.953	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.046	0.954	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.046	0.954	0.000
D51.2 Transcobalamin II deficiency	0.046	0.954	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.046	0.954	0.000
N36.1 Urethral diverticulum	0.044	0.956	0.000
N36.8 Other specified disorders of urethra	0.044	0.956	0.000
N30.4 Irradiation cystitis	0.044	0.956	0.000
N36.3 Prolapsed urethral mucosa	0.044	0.956	0.000
N36.0 Urethral fistula	0.044	0.956	0.000
N35.1 Postinfective urethral stricture, not elsewhere classified	0.043	0.957	0.000
N35.0 Posttraumatic urethral stricture	0.043	0.957	0.000
N30.0 Acute cystitis	0.042	0.958	0.000
N30.8 Other cystitis	0.037	0.963	0.000
N30.9 Cystitis, unspecified	0.034	0.966	0.000
N30.3 Trigonitis	0.033	0.967	0.000
D50-D53 Nutritional anaemias	0.033	0.967	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.029	0.971	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.028	0.972	0.000
D68 Other coagulation defects	0.028	0.972	0.000
K80 Cholelithiasis	0.000	0.972	0.028
D68.6 Other Thrombophilia	0.027	0.973	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.026	0.974	0.000
D66 Hereditary factor VIII deficiency	0.026	0.974	0.000
D68.5 Primary Thrombophilia	0.025	0.975	0.000
M54.22 Cervicalgia (Cervical region)	0.025	0.975	0.000
D73 Diseases of spleen	0.025	0.975	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.976	0.024
D73.9 Disease of spleen, unspecified	0.023	0.977	0.000
D55-D59 Haemolytic anaemias	0.023	0.977	0.000
D68.8 Other specified coagulation defects	0.023	0.977	0.000
D75 Other diseases of blood and blood-forming organs	0.023	0.977	0.000
D80-D89 Certain disorders involving the immune mechanism	0.022	0.978	0.000
D53 Other nutritional anaemias	0.022	0.978	0.000
D73.5 Infarction of spleen	0.021	0.979	0.000
D68.1 Hereditary factor XI deficiency	0.021	0.979	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.979	0.021
D68.0 Von Willebrand's disease	0.021	0.979	0.000
D67 Hereditary factor IX deficiency	0.020	0.979	0.000
S09 Other and unspecified injuries of head	0.000	0.979	0.020
D75.1 Secondary polycythaemia	0.020	0.979	0.000
D68.4 Acquired coagulation factor deficiency	0.020	0.980	0.000
K80.3 Calculus of bile duct with cholangitis	0.000	0.980	0.020
D73.3 Abscess of spleen	0.020	0.980	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.020	0.980	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.980	0.020
D60-D64 Aplastic and other anaemias	0.020	0.980	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.981	0.019
D74 Methaemoglobinaemia	0.019	0.981	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.019	0.981	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.019	0.981	0.000
D62 Acute posthaemorrhagic anaemia	0.019	0.981	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.018	0.981	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.018	0.982	0.000
D52 Folate deficiency anaemia	0.018	0.982	0.000
D73.4 Cyst of spleen	0.018	0.982	0.000
D73.2 Chronic congestive splenomegaly	0.018	0.982	0.000
D73.1 Hypersplenism	0.018	0.982	0.000
D86 Sarcoidosis	0.018	0.982	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.018	0.982	0.000
N35.9 Urethral stricture, unspecified	0.018	0.982	0.000
D59 Acquired haemolytic anaemia	0.018	0.982	0.000
D75.0 Familial erythrocytosis	0.018	0.982	0.000
D58 Other hereditary haemolytic anaemias	0.017	0.983	0.000
D75.2 Essential thrombocytosis	0.017	0.983	0.000
D68.2 Hereditary deficiency of other clotting factors	0.017	0.983	0.000
D56 Thalassaemia	0.017	0.983	0.000
D72 Other disorders of white blood cells	0.017	0.983	0.000
D57 Sickle-cell disorders	0.017	0.983	0.000
D55 Anaemia due to enzyme disorders	0.017	0.983	0.000
D68.9 Coagulation defect, unspecified	0.017	0.983	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.016	0.983	0.000
D82 Immunodeficiency associated with other major defects	0.016	0.984	0.000
D81 Combined immunodeficiencies	0.016	0.984	0.000
D53.8 Other specified nutritional anaemias	0.016	0.984	0.000
D53.2 Scorbutic anaemia	0.016	0.984	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.016	0.984	0.000
D53.0 Protein deficiency anaemia	0.016	0.984	0.000
D80 Immunodeficiency with predominantly antibody defects	0.016	0.984	0.000
D83 Common variable immunodeficiency	0.016	0.984	0.000
D73.0 Hyposplenism	0.016	0.984	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.016	0.984	0.000
D84 Other immunodeficiencies	0.016	0.984	0.000
D86.0 Sarcoidosis of lung	0.016	0.984	0.000
S09.8 Other specified injuries of head	0.000	0.985	0.015
S09.7 Multiple injuries of head	0.000	0.985	0.015
S09.2 Traumatic rupture of ear drum	0.000	0.985	0.015
S09.1 Injury of muscle and tendon of head	0.000	0.985	0.015
M54.2 Cervicalgia	0.015	0.985	0.000
D61 Other aplastic anaemias	0.015	0.985	0.000
D53.9 Nutritional anaemia, unspecified	0.015	0.985	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.985	0.015
D73.8 Other diseases of spleen	0.014	0.985	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.014	0.985	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.014	0.985	0.000
D59.1 Other autoimmune haemolytic anaemias	0.014	0.986	0.000
D86.8 Sarcoidosis of other and combined sites	0.014	0.986	0.000
D74.9 Methaemoglobinaemia, unspecified	0.014	0.986	0.000
D74.8 Other methaemoglobinaemias	0.014	0.986	0.000
D74.0 Congenital methaemoglobinaemia	0.014	0.986	0.000
N39.9 Disorder of urinary system, unspecified	0.013	0.986	0.001
D76.2 Haemophagocytic syndrome, infection-associated	0.013	0.986	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.013	0.986	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.013	0.986	0.000
K80.8 Other cholelithiasis	0.000	0.987	0.013
D58.0 Hereditary spherocytosis	0.013	0.987	0.000
D52.8 Other folate deficiency anaemias	0.013	0.987	0.000
D52.1 Drug-induced folate deficiency anaemia	0.013	0.987	0.000
D52.0 Dietary folate deficiency anaemia	0.013	0.987	0.000
D76.3 Other histiocytosis syndromes	0.013	0.987	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.987	0.013
D59.8 Other acquired haemolytic anaemias	0.013	0.987	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.013	0.987	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.013	0.987	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.013	0.987	0.000
D59.3 Haemolytic-uraemic syndrome	0.013	0.987	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.013	0.987	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.013	0.987	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.013	0.987	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.013	0.987	0.000
D58.2 Other haemoglobinopathies	0.013	0.987	0.000
D58.1 Hereditary elliptocytosis	0.013	0.987	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.013	0.987	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.013	0.987	0.000
D86.3 Sarcoidosis of skin	0.012	0.987	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.012	0.987	0.000
D56.1 Beta thalassaemia	0.012	0.988	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.012	0.988	0.000
D56.9 Thalassaemia, unspecified	0.012	0.988	0.000
D56.8 Other thalassaemias	0.012	0.988	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.012	0.988	0.000
D56.2 Delta-beta thalassaemia	0.012	0.988	0.000
D56.0 Alpha thalassaemia	0.012	0.988	0.000
D72.9 Disorder of white blood cells, unspecified	0.012	0.988	0.000
D72.0 Genetic anomalies of leukocytes	0.012	0.988	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.012	0.988	0.000
D55.8 Other anaemias due to enzyme disorders	0.012	0.988	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.012	0.988	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.012	0.988	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.012	0.988	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.012	0.988	0.000
D57.8 Other sickle-cell disorders	0.012	0.988	0.000
D57.3 Sickle-cell trait	0.012	0.988	0.000
D57.2 Double heterozygous sickling disorders	0.012	0.988	0.000
D57.1 Sickle-cell anaemia without crisis	0.012	0.988	0.000
D57.0 Sickle-cell anaemia with crisis	0.012	0.988	0.000
D56.3 Thalassaemia trait	0.012	0.988	0.000
D89.1 Cryoglobulinaemia	0.012	0.988	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.012	0.988	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.012	0.988	0.000
D89.3 Immune reconstitution syndrome	0.012	0.988	0.000
D72.8 Other specified disorders of white blood cells	0.012	0.988	0.000
D81.9 Combined immunodeficiency, unspecified	0.012	0.988	0.000
D81.8 Other combined immunodeficiencies	0.012	0.988	0.000
D81.7 Major histocompatibility complex class II deficiency	0.012	0.988	0.000
D81.6 Major histocompatibility complex class I deficiency	0.012	0.988	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.012	0.988	0.000
D81.4 Nezelof's syndrome	0.012	0.988	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.012	0.988	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.012	0.988	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.012	0.988	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.012	0.988	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.012	0.988	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.012	0.988	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.012	0.988	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.012	0.988	0.000
D82.2 Immunodeficiency with short-limbed stature	0.012	0.988	0.000
D82.1 Di George's syndrome	0.012	0.988	0.000
D82.0 Wiskott-Aldrich syndrome	0.012	0.988	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.012	0.988	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.012	0.988	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.012	0.988	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.012	0.988	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.012	0.988	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.012	0.988	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.012	0.988	0.000
D61.9 Aplastic anaemia, unspecified	0.012	0.988	0.000
D83.8 Other common variable immunodeficiencies	0.012	0.988	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.012	0.988	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.012	0.988	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.012	0.988	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.012	0.988	0.000
D84.8 Other specified immunodeficiencies	0.011	0.988	0.000
D84.1 Defects in the complement system	0.011	0.988	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.011	0.988	0.000
M54.23 Cervicalgia (Cervicothoracic region)	0.012	0.988	0.000
D83.9 Common variable immunodeficiency, unspecified	0.011	0.989	0.000
N93 Other abnormal uterine and vaginal bleeding	0.011	0.989	0.000
D84.9 Immunodeficiency, unspecified	0.011	0.989	0.000
D86.1 Sarcoidosis of lymph nodes	0.011	0.989	0.000
M54.29 Cervicalgia-Site unspe	0.011	0.989	0.000
M54.28 Cervicalgia-Sacral/sacrococ	0.011	0.989	0.000
M54.27 Cervicalgia-Lumbosacral	0.011	0.989	0.000
M54.26 Cervicalgia-Lumbar	0.011	0.989	0.000
M54.25 Cervicalgia-Thoracolumbar	0.011	0.989	0.000
M54.24 Cervicalgia-Thoracic	0.011	0.989	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.011	0.989	0.000
M54.20 Cervicalgia-Mult site	0.011	0.989	0.000
D61.8 Other specified aplastic anaemias	0.011	0.989	0.000
D61.3 Idiopathic aplastic anaemia	0.011	0.989	0.000
D61.2 Aplastic anaemia due to other external agents	0.011	0.989	0.000
D61.1 Drug-induced aplastic anaemia	0.011	0.989	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.010	0.989	0.000
D60.8 Other acquired pure red cell aplasias	0.010	0.989	0.000
D60.1 Transient acquired pure red cell aplasia	0.010	0.989	0.000
D60.0 Chronic acquired pure red cell aplasia	0.010	0.989	0.000
D72.1 Eosinophilia	0.010	0.989	0.000
D61.0 Constitutional aplastic anaemia	0.010	0.989	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.010	0.990	0.000
D69 Purpura and other haemorrhagic conditions	0.010	0.990	0.000
J03.9 Acute tonsillitis, unspecified	0.010	0.990	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.009	0.990	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.009	0.991	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
D69.5 Secondary thrombocytopenia	0.008	0.992	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.008	0.992	0.000
D52.9 Folate deficiency anaemia, unspecified	0.007	0.992	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.007	0.993	0.000
D69.0 Allergic purpura	0.007	0.993	0.000
D69.8 Other specified haemorrhagic conditions	0.007	0.993	0.000
D69.2 Other nonthrombocytopenic purpura	0.007	0.993	0.000
D69.1 Qualitative platelet defects	0.007	0.993	0.000
D69.4 Other primary thrombocytopenia	0.007	0.993	0.000
D63.0 Anaemia in neoplastic disease	0.007	0.993	0.000
D69.9 Haemorrhagic condition, unspecified	0.007	0.993	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.007	0.993	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
D64 Other anaemias	0.006	0.994	0.000
D70 Agranulocytosis	0.006	0.994	0.000
M54.5 Low back pain	0.006	0.994	0.000
O72.1 Other immediate postpartum haemorrhage	0.006	0.994	0.000
M54 Dorsalgia	0.006	0.994	0.000
M54.56 Low back pain (Lumbar region)	0.006	0.994	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.994	0.006
D86.9 Sarcoidosis, unspecified	0.006	0.994	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
S32.50 Fracture of pubis (closed)	0.000	0.995	0.005
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
J03 Acute tonsillitis	0.005	0.995	0.000
C15.9 Oesophagus, unspecified	0.005	0.995	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
M54.6 Pain in thoracic spine	0.005	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
D64.4 Congenital dyserythropoietic anaemia	0.005	0.995	0.000
D64.3 Other sideroblastic anaemias	0.005	0.995	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.005	0.995	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.005	0.995	0.000
D64.0 Hereditary sideroblastic anaemia	0.005	0.995	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
M54.53 Low back pain-Cervicothoracic	0.005	0.995	0.000
M54.52 Low back pain-Cervical	0.005	0.995	0.000
M54.51 Low back pain-Occipit-atl-axl	0.005	0.995	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
C16.9 Stomach, unspecified	0.005	0.995	0.000
M54.54 Low back pain-Thoracic	0.004	0.995	0.000
M54.0 Panniculitis affecting regions of neck and back	0.004	0.995	0.000
I44.1 Atrioventricular block, second degree	0.000	0.995	0.005
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
M54.55 Low back pain (Thoracolumbar region)	0.004	0.996	0.000
M54.1 Radiculopathy	0.004	0.996	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.004	0.996	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.996	0.004
M24.23 Disorder of ligament (Forearm)	0.004	0.996	0.000
K86.8 Other specified diseases of pancreas	0.000	0.996	0.004
O72 Postpartum haemorrhage	0.004	0.996	0.000
M54.12 Radiculopathy (Cervical region)	0.004	0.996	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.004	0.996	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.996	0.004
K86 Other diseases of pancreas	0.000	0.996	0.004
M24.28 Disorder of ligament (Other)	0.004	0.996	0.000
O72.0 Third-stage haemorrhage	0.004	0.996	0.000
M54.8 Other dorsalgia	0.004	0.996	0.000
N39.0 Urinary tract infection, site not specified	0.004	0.996	0.000
N93.0 Postcoital and contact bleeding	0.004	0.996	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.996	0.004
M54.50 Low back pain (Multiple sites in spine)	0.004	0.996	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.004	0.996	0.000
J03.0 Streptococcal tonsillitis	0.004	0.996	0.000
M54.9 Dorsalgia, unspecified	0.004	0.996	0.000
C15 Malignant neoplasm of oesophagus	0.004	0.996	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.996	0.004
M54.57 Low back pain (Lumbosacral region)	0.004	0.996	0.000
M54.92 Dorsalgia, unspecified (Cervical region)	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
M24.2 Disorder of ligament	0.004	0.996	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.996	0.004
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.004	0.996	0.000
M54.69 Pain in thoracic spine-Site unspe	0.004	0.996	0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.004	0.996	0.000
M54.67 Pain in thoracic spine-Lumbosacral	0.004	0.996	0.000
M54.66 Pain in thoracic spine-Lumbar	0.004	0.996	0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.004	0.996	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.004	0.996	0.000
M54.62 Pain in thoracic spine-Cervical	0.004	0.996	0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.004	0.996	0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.004	0.996	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.004	0.996	0.000
D64.8 Other specified anaemias	0.004	0.996	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.004	0.996	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
C15.4 Middle third of oesophagus	0.004	0.996	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.000	0.996	0.004
C16 Malignant neoplasm of stomach	0.004	0.996	0.000
M54.14 Radiculopathy (Thoracic region)	0.004	0.996	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.996	0.004
M24.21 Disorder of ligament (Shoulder region)	0.004	0.996	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.996	0.004
T92.1 Sequelae of fracture of arm	0.004	0.996	0.000
S82.00 Fracture of patella (closed)	0.004	0.996	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.003	0.996	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.003	0.996	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.003	0.996	0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.003	0.996	0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.003	0.996	0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.003	0.996	0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.003	0.996	0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.003	0.996	0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.003	0.996	0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.003	0.996	0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.003	0.996	0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.003	0.996	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.003	0.996	0.000
C92.1 Chronic myeloid leukaemia	0.003	0.996	0.000
H04.2 Epiphora	0.004	0.996	0.000
C16.2 Body of stomach	0.003	0.997	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.003	0.997	0.000
M54.15 Radiculopathy (Thoracolumbar region)	0.003	0.997	0.000
M54.13 Radiculopathy (Cervicothoracic region)	0.003	0.997	0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.003	0.997	0.000
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.003	0.997	0.000
M54.19 Radiculopathy (Site unspecified)	0.003	0.997	0.000
C15.0 Cervical part of oesophagus	0.003	0.997	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.003	0.997	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.997	0.003
T92 Sequelae of injuries of upper limb	0.003	0.997	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.003	0.997	0.000
S32.5 Fracture of pubis	0.000	0.997	0.003
C15.3 Upper third of oesophagus	0.003	0.997	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.997	0.003
T90.4 Sequelae of injury of eye and orbit	0.003	0.997	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.000	0.997	0.003
C16.4 Pylorus	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
T90 Sequelae of injuries of head	0.003	0.997	0.000
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
M47.12 Other spondylosis with myelopathy (Cervical region)	0.003	0.997	0.000
O72.3 Postpartum coagulation defects	0.003	0.997	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.000	0.997	0.003
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M54.87 Other dorsalgia (Lumbosacral region)	0.003	0.997	0.000
M54.86 Other dorsalgia (Lumbar region)	0.003	0.997	0.000
M54.85 Other dorsalgia (Thoracolumbar region)	0.003	0.997	0.000
M54.84 Other dorsalgia (Thoracic region)	0.003	0.997	0.000
M54.83 Other dorsalgia (Cervicothoracic region)	0.003	0.997	0.000
M54.82 Other dorsalgia (Cervical region)	0.003	0.997	0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.003	0.997	0.000
M54.80 Other dorsalgia (Multiple sites in spine)	0.003	0.997	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.003	0.997	0.000
E87.1 Hypo-osmolality and hyponatraemia	0.003	0.997	0.000
K86.3 Pseudocyst of pancreas	0.000	0.997	0.003
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.003	0.997	0.000
C16.3 Pyloric antrum	0.003	0.997	0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.003	0.997	0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.003	0.997	0.000
C15.8 Overlapping lesion of oesophagus	0.003	0.997	0.000
C15.2 Abdominal part of oesophagus	0.003	0.997	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.003	0.997	0.000
S81.9 Open wound of lower leg, part unspecified	0.003	0.997	0.000
M24.29 Disorder of ligament (Site unspecified)	0.003	0.997	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.003	0.997	0.000
M24.22 Disorder of ligament (Upper arm)	0.003	0.997	0.000
M24.20 Disorder of ligament (Multiple sites)	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.003	0.997	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.003	0.997	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.997	0.003
C50.3 Lower-inner quadrant of breast	0.003	0.997	0.000
K85 Acute pancreatitis	0.000	0.997	0.003
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.003	0.997	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.997	0.000
C16.8 Overlapping lesion of stomach	0.003	0.997	0.000
C16.1 Fundus of stomach	0.003	0.997	0.000
Z51.3 Blood transfusion without reported diagnosis	0.003	0.997	0.000
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.997	0.003
T92.4 Sequelae of injury of nerve of upper limb	0.003	0.997	0.000
M54.89 Other dorsalgia (Site unspecified)	0.003	0.997	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.003	0.997	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.000	0.997	0.003
I69 Sequelae of cerebrovascular disease	0.000	0.997	0.003
K82 Other diseases of gallbladder	0.000	0.997	0.003
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
T91 Sequelae of injuries of neck and trunk	0.003	0.997	0.000
M24.24 Disorder of ligament (Hand)	0.003	0.997	0.000
C92 Myeloid leukaemia	0.003	0.997	0.000
K82.9 Disease of gallbladder, unspecified	0.000	0.997	0.003
T84.3 Mechanical complication of other bone devices, implants and grafts	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.997	0.003
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.997	0.002
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.997	0.002
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.003	0.997	0.000
S32.51 Fracture of pubis (open)	0.000	0.997	0.002
T82.3 Mechanical complication of other vascular grafts	0.000	0.997	0.003
T90.3 Sequelae of injury of cranial nerves	0.003	0.997	0.000
T90.0 Sequelae of superficial injury of head	0.003	0.997	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.003	0.997	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.000	0.997	0.002
T90.1 Sequelae of open wound of head	0.002	0.997	0.000
C15.5 Lower third of oesophagus	0.003	0.997	0.000
K82.3 Fistula of gallbladder	0.000	0.997	0.003
T92.2 Sequelae of fracture at wrist and hand level	0.003	0.997	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.997	0.003
M24.02 Loose body in joint (Upper arm)	0.003	0.997	0.000
M24 Other specific joint derangements	0.003	0.997	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.003	0.997	0.000
N41.1 Chronic prostatitis	0.003	0.997	0.000
W02.9 Unspecified place	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.002	0.997	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.997	0.002
M24.0 Loose body in joint	0.002	0.997	0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.003	0.997	0.000
T90.8 Sequelae of other specified injuries of head	0.002	0.997	0.000
D50 Iron deficiency anaemia	0.002	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.000	0.998	0.002
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.002	0.998	0.000
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.002	0.998	0.000
M54.4 Lumbago with sciatica	0.002	0.998	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.002	0.998	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.002	0.998	0.000
U80.1 Methicillin resistant agent	0.002	0.998	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
K85.8 Other acute pancreatitis	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.000	0.998	0.002
K85.0 Idiopathic acute pancreatitis	0.000	0.998	0.002
K82.2 Perforation of gallbladder	0.000	0.998	0.002
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations