TreeWAS – Variant ID: rs2227667

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z36.9 Antenatal screening, unspecified	0.112	0.888	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.103	0.897	0.000
Z36 Antenatal screening	0.103	0.897	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.081	0.919	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.080	0.920	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.075	0.925	0.000
Z36.5 Antenatal screening for isoimmunisation	0.074	0.926	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.073	0.927	0.000
Z36.8 Other antenatal screening	0.055	0.945	0.000
C90.0 Multiple myeloma	0.018	0.982	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.985	0.015
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.987	0.013
U80.0 Penicillin resistant agent	0.000	0.987	0.013
U89 Agent resistant to other and unspecified antibiotics	0.000	0.988	0.012
U89.8 Agent resistant to other single specified antibiotic	0.000	0.988	0.012
T42.4 Benzodiazepines	0.000	0.989	0.011
U80 Agent resistant to penicillin and related antibiotics	0.000	0.990	0.010
U84 Resistance to other antimicrobial drugs	0.000	0.990	0.010
U83 Resistance to other antibiotics	0.000	0.990	0.010
U82 Resistance to betalactam antibiotics	0.000	0.990	0.010
U85 Resistance to antineoplastic drugs	0.000	0.990	0.010
Chapter XXII Codes for special purposes	0.000	0.990	0.010
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.990	0.010
U89.9 Agent resistant to unspecified antibiotic	0.000	0.991	0.009
C90 Multiple myeloma and malignant plasma cell neoplasms	0.009	0.991	0.000
U51 Admission status on psychiatric patients	0.000	0.992	0.008
S00.8 Superficial injury of other parts of head	0.008	0.992	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.007	0.993	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.993	0.007
U82.8 Resistance to other betalactam antibiotics	0.000	0.993	0.007
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.993	0.007
U82.1 Resistance to methicillin	0.000	0.993	0.007
U82.0 Resistance to penicillin	0.000	0.993	0.007
U83.9 Resistance to unspecified antibiotic	0.000	0.993	0.007
U83.8 Resistance to other single specified antibiotic	0.000	0.993	0.007
U83.7 Resistance to multiple antibiotics	0.000	0.993	0.007
U83.2 Resistance to quinolones	0.000	0.993	0.007
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.993	0.007
U83.0 Resistance to vancomycin	0.000	0.993	0.007
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.993	0.007
U84.8 Resistance to other specified antimicrobial drug	0.000	0.993	0.007
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.993	0.007
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.993	0.007
U84.2 Resistance to antiviral drug(s)	0.000	0.993	0.007
U84.1 Resistance to antifungal drug(s)	0.000	0.993	0.007
U84.0 Resistance to antiparasitic drug(s)	0.000	0.993	0.007
U50 Level of care administered to neonates	0.000	0.993	0.007
U07 Emergency use of U07	0.000	0.993	0.007
U06 Emergency use of U06	0.000	0.993	0.007
U04 Severe acute respiratory syndrome [SARS]	0.000	0.993	0.007
U52 First in a series of a regular day/night admissions	0.000	0.993	0.007
C90.1 Plasma cell leukaemia	0.007	0.993	0.000
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.993	0.007
C90.2 Plasmacytoma, extramedullary	0.007	0.993	0.000
C90.3 Solitary plasmacytoma	0.007	0.993	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.993	0.007
U81 Agent resistant to vancomycin and related antibiotics	0.000	0.993	0.006
U51.1 Previously admitted to a psychiatric hospital of the provider	0.000	0.993	0.007
U51.2 Previously admitted to a psychiatric hospital of another provider	0.000	0.994	0.006
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.994	0.006
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.994	0.006
Y60.0 During surgical operation	0.006	0.994	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.006	0.994	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.994	0.006
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.000	0.995	0.005
U06.9 Emergency use of U06.9	0.000	0.995	0.005
U06.8 Emergency use of U06.8	0.000	0.995	0.005
U06.7 Emergency use of U06.7	0.000	0.995	0.005
U06.6 Emergency use of U06.6	0.000	0.995	0.005
U06.5 Emergency use of U06.5	0.000	0.995	0.005
U06.4 Emergency use of U06.4	0.000	0.995	0.005
U06.3 Emergency use of U06.3	0.000	0.995	0.005
U06.2 Emergency use of U06.2	0.000	0.995	0.005
U06.1 Emergency use of U06.1	0.000	0.995	0.005
U06.0 Emergency use of U06.0	0.000	0.995	0.005
U07.9 Emergency use of U07.9	0.000	0.995	0.005
U07.8 Emergency use of U07.8	0.000	0.995	0.005
U07.7 Emergency use of U07.7	0.000	0.995	0.005
U07.6 Emergency use of U07.6	0.000	0.995	0.005
U07.5 Emergency use of U07.5	0.000	0.995	0.005
U07.4 Emergency use of U07.4	0.000	0.995	0.005
U07.3 Emergency use of U07.3	0.000	0.995	0.005
U07.2 Emergency use of U07.2	0.000	0.995	0.005
U07.1 Emergency use of U07.1	0.000	0.995	0.005
U07.0 Emergency use of U07.0	0.000	0.995	0.005
U50.9 Inquest Adjourned Death	0.000	0.995	0.005
U50.3 Level of care administered to neonates (Maximal Intensive Care)	0.000	0.995	0.005
U50.2 Level of care administered to neonates (High Dependancy Intensive Care)	0.000	0.995	0.005
U50.1 Level of care administered to neonates (Special Care)	0.000	0.995	0.005
U50.0 Level of care administered to neonates (Normal Care)	0.000	0.995	0.005
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.995	0.005
T42.0 Hydantoin derivatives	0.000	0.995	0.005
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.995	0.005
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.995	0.005
T42.3 Barbiturates	0.000	0.995	0.005
T42.2 Succinimides and oxazolidinediones	0.000	0.995	0.005
U81.8 Agent resistant to other vancomycin-related antibiotic	0.000	0.995	0.005
U80.1 Methicillin resistant agent	0.000	0.995	0.005
K62.1 Rectal polyp	0.004	0.996	0.000
U81.0 Vancomycin resistant agent	0.000	0.996	0.004
N87.1 Moderate cervical dysplasia	0.000	0.996	0.004
D04.4 Skin of scalp and neck	0.000	0.996	0.004
D04.6 Skin of upper limb, including shoulder	0.000	0.996	0.004
Q61.3 Polycystic kidney, unspecified	0.000	0.996	0.004
T42.1 Iminostilbenes	0.000	0.996	0.004
K35.1 Acute appendicitis with peritoneal abscess	0.004	0.996	0.000
S62.61 Fracture of other finger (open)	0.004	0.996	0.000
M48.06 Spinal stenosis (Lumbar region)	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.004	0.996	0.000
D04 Carcinoma in situ of skin	0.000	0.997	0.003
T87.6 Other and unspecified complications of amputation stump	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.003	0.997	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
Y60.4 During endoscopic examination	0.003	0.997	0.000
E28.3 Primary ovarian failure	0.003	0.997	0.000
K12.3 Oral mucositis (ulcerative)	0.003	0.997	0.000
L60.8 Other nail disorders	0.003	0.997	0.000
D04.2 Skin of ear and external auricular canal	0.000	0.997	0.003
D04.5 Skin of trunk	0.000	0.997	0.003
E28 Ovarian dysfunction	0.003	0.997	0.000
Y60.9 During unspecified surgical and medical care	0.003	0.997	0.000
Y60.7 During administration of enema	0.003	0.997	0.000
Y60.6 During aspiration, puncture and other catheterisation	0.003	0.997	0.000
Y60.5 During heart catheterisation	0.003	0.997	0.000
Y60.3 During injection or immunisation	0.003	0.997	0.000
Y60.2 During kidney dialysis or other perfusion	0.003	0.997	0.000
Y60.1 During infusion or transfusion	0.003	0.997	0.000
N10 Acute tubulo-interstitial nephritis	0.003	0.997	0.000
B18 Chronic viral hepatitis	0.003	0.997	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.997	0.003
D04.8 Skin of other sites	0.000	0.997	0.003
D04.1 Skin of eyelid, including canthus	0.000	0.997	0.003
D04.0 Skin of lip	0.000	0.997	0.003
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.997	0.003
Q61 Cystic kidney disease	0.000	0.997	0.003
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
B18.1 Chronic viral hepatitis B without delta-agent	0.003	0.997	0.000
D04.9 Skin, unspecified	0.000	0.997	0.003
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.997	0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
I42.0 Dilated cardiomyopathy	0.003	0.997	0.000
R84.5 Abnormal microbiological findings	0.003	0.997	0.000
R06.8 Other and unspecified abnormalities of breathing	0.003	0.997	0.000
S62.6 Fracture of other finger	0.003	0.997	0.000
T36.0 Penicillins	0.000	0.997	0.002
Y60.8 During other surgical and medical care	0.002	0.997	0.000
D04.7 Skin of lower limb, including hip	0.000	0.998	0.002
K14.0 Glossitis	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T87.4 Infection of amputation stump	0.002	0.998	0.000
T87 Complications peculiar to reattachment and amputation	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.998	0.002
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
E28.9 Ovarian dysfunction, unspecified	0.002	0.998	0.000
E28.8 Other ovarian dysfunction	0.002	0.998	0.000
E28.1 Androgen excess	0.002	0.998	0.000
E28.0 Oestrogen excess	0.002	0.998	0.000
T87.3 Neuroma of amputation stump	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.000	0.998	0.002
B18.9 Chronic viral hepatitis, unspecified	0.002	0.998	0.000
B18.8 Other chronic viral hepatitis	0.002	0.998	0.000
B18.0 Chronic viral hepatitis B with delta-agent	0.002	0.998	0.000
Z52.4 Kidney donor	0.000	0.998	0.002
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
N10-N16 Renal tubulo-interstitial diseases	0.002	0.998	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
N11 Chronic tubulo-interstitial nephritis	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
R06.0 Dyspnoea	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.998	0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.998	0.002
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.998	0.002
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.998	0.002
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.998	0.002
T44.0 Anticholinesterase agents	0.000	0.998	0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.002	0.998	0.000
N45 Orchitis and epididymitis	0.002	0.998	0.000
H91.9 Hearing loss, unspecified	0.002	0.998	0.000
N15 Other renal tubulo-interstitial diseases	0.002	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
K12 Stomatitis and related lesions	0.002	0.998	0.000
T87.5 Necrosis of amputation stump	0.002	0.998	0.000
T87.2 Complications of other reattached body part	0.002	0.998	0.000
T87.1 Complications of reattached (part of) lower extremity	0.002	0.998	0.000
T87.0 Complications of reattached (part of) upper extremity	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
T36.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
T36.8 Other systemic antibiotics	0.000	0.998	0.002
T36.7 Antifungal antibiotics, systemically used	0.000	0.998	0.002
T36.6 Rifamycins	0.000	0.998	0.002
T36.5 Aminoglycosides	0.000	0.998	0.002
T36.4 Tetracyclines	0.000	0.998	0.002
T36.3 Macrolides	0.000	0.998	0.002
T36.2 Chloramphenicol group	0.000	0.998	0.002
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.998	0.002
D09.0 Bladder	0.000	0.998	0.002
K12.1 Other forms of stomatitis	0.002	0.998	0.000
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.002
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.002
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.002	0.998	0.000
N05.9 Unspecified	0.002	0.998	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.998	0.002
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.002	0.998	0.000
B15.9 Hepatitis A without hepatic coma	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
J06.9 Acute upper respiratory infection, unspecified	0.002	0.998	0.000
S62 Fracture at wrist and hand level	0.002	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
S52.70 Multiple fractures of forearm (closed)	0.002	0.998	0.000
D38.0 Larynx	0.002	0.998	0.000
G47.3 Sleep apnoea	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
B15 Acute hepatitis A	0.002	0.998	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
S62.7 Multiple fractures of fingers	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.002	0.998	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.002	0.998	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.002	0.998	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.002	0.998	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.002	0.998	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.002	0.998	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.002	0.998	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.002	0.998	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.002	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.002	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.002	0.998	0.000
N14.0 Analgesic nephropathy	0.002	0.998	0.000
N87 Dysplasia of cervix uteri	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
B15-B19 Viral hepatitis	0.002	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
Z38 Liveborn infants according to place of birth	0.002	0.998	0.000
D43.2 Brain, unspecified	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
C84.5 Other and unspecified T-cell lymphomas	0.002	0.998	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.002	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.002
B17 Other acute viral hepatitis	0.002	0.998	0.000
S62.60 Fracture of other finger (closed)	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.002	0.998	0.000
C67.4 Posterior wall of bladder	0.000	0.998	0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.998	0.001
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.001
T37.5 Antiviral drugs	0.000	0.998	0.001
T37.4 Anthelminthics	0.000	0.998	0.001
T37.3 Other antiprotozoal drugs	0.000	0.998	0.001
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.001
T37.1 Antimycobacterial drugs	0.000	0.998	0.001
T37.0 Sulphonamides	0.000	0.998	0.001
T41.5 Therapeutic gases	0.000	0.998	0.001
T41.4 Anaesthetic, unspecified	0.000	0.998	0.001
T41.3 Local anaesthetics	0.000	0.998	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.998	0.001
T41.1 Intravenous anaesthetics	0.000	0.998	0.001
T41.0 Inhaled anaesthetics	0.000	0.998	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.998	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.998	0.001
T48.5 Anti-common-cold drugs	0.000	0.998	0.001
T48.4 Expectorants	0.000	0.998	0.001
T48.3 Antitussives	0.000	0.998	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.998	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.998	0.001
T48.0 Oxytocic drugs	0.000	0.998	0.001
Y44.2 Anticoagulants	0.000	0.998	0.002
Z95.4 Presence of other heart-valve replacement	0.000	0.998	0.002
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
S62.31 Fracture of other metacarpal bone (open)	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
Z38.0 Singleton, born in hospital	0.002	0.998	0.000
D38.5 Other respiratory organs	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.002
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.998	0.002
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.998	0.000
S62.1 Fracture of other carpal bone(s)	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.998	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.998	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.998	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.998	0.001
T45.4 Iron and its compounds	0.000	0.998	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.998	0.001
W50.9 Unspecified place	0.002	0.998	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
D38.6 Respiratory organ, unspecified	0.001	0.998	0.000
D38.4 Thymus	0.001	0.998	0.000
D38.3 Mediastinum	0.001	0.998	0.000
D38.2 Pleura	0.001	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
N87.0 Mild cervical dysplasia	0.000	0.998	0.002
S62.4 Multiple fractures of metacarpal bones	0.002	0.998	0.000
S62.2 Fracture of first metacarpal bone	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
D26.9 Uterus, unspecified	0.000	0.998	0.002
D26.1 Corpus uteri	0.000	0.998	0.002
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.001	0.998	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.001	0.998	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.001	0.998	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.001	0.998	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.001	0.998	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.001	0.998	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
R90.0 Intracranial space-occupying lesion	0.002	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
T50.8 Diagnostic agents	0.000	0.998	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.001
T50.5 Appetite depressants	0.000	0.998	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.001
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.001
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.002	0.998	0.000
B15.0 Hepatitis A with hepatic coma	0.001	0.998	0.000
D26.0 Cervix uteri	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.001	0.998	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.002	0.998	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.000	0.998	0.001
T49.8 Other topical agents	0.000	0.998	0.001
T49.7 Dental drugs, topically applied	0.000	0.998	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.998	0.001
T49.2 Local astringents and local detergents	0.000	0.998	0.001
T49.1 Antipruritics	0.000	0.998	0.001
D43.4 Spinal cord	0.001	0.998	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.002	0.998	0.000
L93.0 Discoid lupus erythematosus	0.000	0.998	0.002
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.998	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.998	0.001
T47.7 Emetics	0.000	0.998	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.998	0.001
T47.5 Digestants	0.000	0.998	0.001
T47.4 Other laxatives	0.000	0.998	0.001
T47.3 Saline and osmotic laxatives	0.000	0.998	0.001
T47.2 Stimulant laxatives	0.000	0.998	0.001
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.001
Z38.8 Other multiple, unspecified as to place of birth	0.001	0.998	0.000
Z38.7 Other multiple, born outside hospital	0.001	0.998	0.000
Z38.6 Other multiple, born in hospital	0.001	0.998	0.000
Z38.5 Twin, unspecified as to place of birth	0.001	0.998	0.000
Z38.4 Twin, born outside hospital	0.001	0.998	0.000
Z38.3 Twin, born in hospital	0.001	0.998	0.000
Z38.2 Singleton, unspecified as to place of birth	0.001	0.998	0.000
Z38.1 Singleton, born outside hospital	0.001	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.001	0.998	0.000
B16 Acute hepatitis B	0.001	0.998	0.000
S62.51 Fracture of thumb (open)	0.001	0.998	0.000
B17.9 Acute viral hepatitis, unspecified	0.001	0.998	0.000
B17.8 Other specified acute viral hepatitis	0.001	0.998	0.000
B17.2 Acute hepatitis E	0.001	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.001	0.998	0.000
V43.9 Unspecified car occupant injured in traffic accident	0.001	0.998	0.000
D43.0 Brain, supratentorial	0.001	0.998	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.002	0.998	0.000
K12.0 Recurrent oral aphthae	0.001	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.001
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.001	0.998	0.000
A81.0 Creutzfeldt-Jakob disease	0.001	0.998	0.000
I82.8 Embolism and thrombosis of other specified veins	0.001	0.998	0.000
S01.3 Open wound of ear	0.001	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.000	0.998	0.001
Z37.1 Single stillbirth	0.001	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.998	0.000
D43.1 Brain, infratentorial	0.001	0.999	0.000
S62.5 Fracture of thumb	0.001	0.999	0.000
T38.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
T38.7 Androgens and anabolic congeners	0.000	0.999	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
T38.5 Other oestrogens and progestogens	0.000	0.999	0.001
T38.4 Oral contraceptives	0.000	0.999	0.001
T38.2 Antithyroid drugs	0.000	0.999	0.001
T38.0 Glucocorticoids and synthetic analogues	0.000	0.999	0.001
C80 Malignant neoplasm without specification of site	0.000	0.999	0.001
C84 Peripheral and cutaneous T-cell lymphomas	0.001	0.999	0.000
S62.11 Fracture of other carpal bone(s) (open)	0.001	0.999	0.000
N80.8 Other endometriosis	0.001	0.999	0.000
S02.2 Fracture of nasal bones	0.001	0.999	0.000
T47.0 Histamine H(2)-receptor antagonists	0.000	0.999	0.001
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.999	0.000
S62.21 Fracture of first metacarpal bone (open)	0.001	0.999	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.001	0.999	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.999	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.001	0.999	0.000
T45.5 Anticoagulants	0.000	0.999	0.001
B19 Unspecified viral hepatitis	0.001	0.999	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.001	0.999	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
D43.9 Central nervous system, unspecified	0.001	0.999	0.000
D43.7 Other parts of central nervous system	0.001	0.999	0.000
D43.3 Cranial nerves	0.001	0.999	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.001	0.999	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.001	0.999	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.999	0.001
B24 Unspecified human immunodeficiency virus [HIV] disease	0.001	0.999	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.001	0.999	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.999	0.001
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.999	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.001	0.999	0.000
Z89.5 Acquired absence of leg at or below knee	0.001	0.999	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.999	0.000
C67.2 Lateral wall of bladder	0.000	0.999	0.001
D35.1 Parathyroid gland	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
D26 Other benign neoplasms of uterus	0.000	0.999	0.001
Y64 Contaminated medical or biological substances	0.001	0.999	0.000
Y63 Failure in dosage during surgical and medical care	0.001	0.999	0.000
Y62 Failure of sterile precautions during surgical and medical care	0.001	0.999	0.000
Y61 Foreign object accidentally left in body during surgical and medical care	0.001	0.999	0.000
Y69 Unspecified misadventure during surgical and medical care	0.001	0.999	0.000
Y66 Nonadministration of surgical and medical care	0.001	0.999	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.001	0.999	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.001	0.999	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.001	0.999	0.000
N90.6 Hypertrophy of vulva	0.001	0.999	0.000
C95.0 Acute leukaemia of unspecified cell type	0.001	0.999	0.000
R06.2 Wheezing	0.001	0.999	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.001	0.999	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.001	0.999	0.000
K60.3 Anal fistula	0.000	0.999	0.001
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.999	0.001
Z34.0 Supervision of normal first pregnancy	0.001	0.999	0.000
Z31 Procreative management	0.001	0.999	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.001	0.999	0.000
C67.3 Anterior wall of bladder	0.000	0.999	0.001
C84.9 Mature T/NK-cell lymphoma, unspecified	0.001	0.999	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.001	0.999	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.001	0.999	0.000
C84.3 Lymphoepithelioid lymphoma	0.001	0.999	0.000
C84.2 T-zone lymphoma	0.001	0.999	0.000
C84.1 Sezary's diease	0.001	0.999	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.999	0.001
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
Z71.9 Counselling, unspecified	0.001	0.999	0.000
D09 Carcinoma in situ of other and unspecified sites	0.000	0.999	0.001
Y65 Other misadventures during surgical and medical care	0.001	0.999	0.000
Z32 Pregnancy examination and test	0.001	0.999	0.000
S02.21 Fracture of nasal bones (open)	0.001	0.999	0.000
C05.9 Palate, unspecified	0.001	0.999	0.000
C67.5 Bladder neck	0.000	0.999	0.001
A87.9 Viral meningitis, unspecified	0.001	0.999	0.000
B19.0 Unspecified viral hepatitis with coma	0.001	0.999	0.000
O04.9 Complete or unspecified, without complication	0.001	0.999	0.000
R84.9 Unspecified abnormal finding	0.001	0.999	0.000
R84.8 Other abnormal findings	0.001	0.999	0.000
R84.7 Abnormal histological findings	0.001	0.999	0.000
R84.6 Abnormal cytological findings	0.001	0.999	0.000
R84.4 Abnormal immunological findings	0.001	0.999	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R84.1 Abnormal level of hormones	0.001	0.999	0.000
R84.0 Abnormal level of enzymes	0.001	0.999	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.999	0.001
T40.8 Lysergide [LSD]	0.000	0.999	0.001
T40.7 Cannabis (derivatives)	0.000	0.999	0.001
T40.3 Methadone	0.000	0.999	0.001
T40.1 Heroin	0.000	0.999	0.001
T40.0 Opium	0.000	0.999	0.001
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations