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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2228467
log Bayes Factor = 0.104304
Chromosome 3   position 42,906,116  (GRCh37) Explore rs2228467 on Ensembl!
Variant rs2228467 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.128 0.872 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.120 0.880 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.119 0.881 0.000
K04 Diseases of pulp and periapical tissues
0.116 0.884 0.000
K13 Other diseases of lip and oral mucosa
0.116 0.884 0.000
K08 Other disorders of teeth and supporting structures
0.112 0.888 0.000
K04.8 Radicular cyst
0.111 0.889 0.000
K13.0 Diseases of lips
0.110 0.890 0.000
K08.3 Retained dental root
0.107 0.893 0.000
K14 Diseases of tongue
0.105 0.895 0.000
K90-K93 Other diseases of the digestive system
0.105 0.895 0.000
K91.3 Postoperative intestinal obstruction
0.102 0.898 0.000
K90 Intestinal malabsorption
0.100 0.900 0.000
K00 Disorders of tooth development and eruption
0.098 0.902 0.000
K09 Cysts of oral region, not elsewhere classified
0.098 0.902 0.000
K90.0 Coeliac disease
0.097 0.903 0.000
K04.7 Periapical abscess without sinus
0.097 0.903 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.097 0.903 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.097 0.903 0.000
K14.8 Other diseases of tongue
0.096 0.904 0.000
K04.6 Periapical abscess with sinus
0.095 0.905 0.000
K04.5 Chronic apical periodontitis
0.094 0.906 0.000
K05 Gingivitis and periodontal diseases
0.093 0.907 0.000
K91.0 Vomiting following gastro-intestinal surgery
0.092 0.908 0.000
K91.1 Postgastric surgery syndromes
0.092 0.908 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.089 0.911 0.000
K12 Stomatitis and related lesions
0.088 0.912 0.000
K07 Dentofacial anomalies [including malocclusion]
0.086 0.914 0.000
K91.9 Postprocedural disorder of digestive system, unspecified
0.086 0.914 0.000
K91.5 Postcholecystectomy syndrome
0.086 0.914 0.000
K91.2 Postsurgical malabsorption, not elsewhere classified
0.086 0.914 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.086 0.914 0.000
K03 Other diseases of hard tissues of teeth
0.085 0.915 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.085 0.915 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.084 0.916 0.000
K04.3 Abnormal hard tissue formation in pulp
0.084 0.916 0.000
K04.2 Pulp degeneration
0.084 0.916 0.000
K04.1 Necrosis of pulp
0.084 0.916 0.000
K04.0 Pulpitis
0.083 0.917 0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.083 0.917 0.000
K13.5 Oral submucous fibrosis
0.083 0.917 0.000
K13.3 Hairy leukoplakia
0.083 0.917 0.000
K13.1 Cheek and lip biting
0.083 0.917 0.000
K14.0 Glossitis
0.081 0.918 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.081 0.919 0.000
K05.6 Periodontal disease, unspecified
0.081 0.919 0.000
K91.4 Colostomy and enterostomy malfunction
0.080 0.920 0.000
O60-O75 Complications of labour and delivery
0.079 0.921 0.000
K00.6 Disturbances in tooth eruption
0.079 0.921 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.079 0.921 0.000
K01 Embedded and impacted teeth
0.079 0.921 0.000
K00.9 Disorder of tooth development, unspecified
0.076 0.924 0.000
K09.9 Cyst of oral region, unspecified
0.076 0.924 0.000
K09.2 Other cysts of jaw
0.076 0.924 0.000
K05.1 Chronic gingivitis
0.076 0.924 0.000
K14.6 Glossodynia
0.075 0.925 0.000
K14.5 Plicated tongue
0.075 0.925 0.000
K14.4 Atrophy of tongue papillae
0.075 0.925 0.000
K14.3 Hypertrophy of tongue papillae
0.075 0.925 0.000
K14.2 Median rhomboid glossitis
0.075 0.925 0.000
K14.1 Geographic tongue
0.075 0.925 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.075 0.925 0.000
O63 Long labour
0.075 0.925 0.000
K09.0 Developmental odontogenic cysts
0.073 0.926 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.074 0.926 0.000
K90.9 Intestinal malabsorption, unspecified
0.073 0.927 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.073 0.927 0.000
K92 Other diseases of digestive system
0.072 0.928 0.000
K90.8 Other intestinal malabsorption
0.072 0.928 0.000
K90.3 Pancreatic steatorrhoea
0.072 0.928 0.000
K90.2 Blind loop syndrome, not elsewhere classified
0.072 0.928 0.000
K90.1 Tropical sprue
0.072 0.928 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.071 0.928 0.000
O62 Abnormalities of forces of labour
0.071 0.929 0.000
K11 Diseases of salivary glands
0.071 0.929 0.000
K00.8 Other disorders of tooth development
0.070 0.930 0.000
K00.7 Teething syndrome
0.070 0.930 0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified
0.070 0.930 0.000
K00.4 Disturbances in tooth formation
0.070 0.930 0.000
K00.3 Mottled teeth
0.070 0.930 0.000
K00.2 Abnormalities of size and form of teeth
0.070 0.930 0.000
K00.1 Supernumerary teeth
0.070 0.930 0.000
K00.0 Anodontia
0.070 0.930 0.000
K12.3 Oral mucositis (ulcerative)
0.070 0.930 0.000
K09.1 Developmental (nonodontogenic) cysts of oral region
0.070 0.930 0.000
O72 Postpartum haemorrhage
0.070 0.930 0.000
O16 Unspecified maternal hypertension
0.070 0.930 0.000
K09.8 Other cysts of oral region, not elsewhere classified
0.070 0.930 0.000
O63.0 Prolonged first stage (of labour)
0.069 0.931 0.000
K02 Dental caries
0.068 0.932 0.000
K07.6 Temporomandibular joint disorders
0.067 0.933 0.000
O70 Perineal laceration during delivery
0.067 0.933 0.000
K05.2 Acute periodontitis
0.067 0.933 0.000
K05.5 Other periodontal diseases
0.067 0.933 0.000
K05.4 Periodontosis
0.067 0.933 0.000
K05.0 Acute gingivitis
0.067 0.933 0.000
K92.1 Melaena
0.066 0.934 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.066 0.934 0.000
O71 Other obstetric trauma
0.065 0.935 0.000
K14.9 Disease of tongue, unspecified
0.064 0.936 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.064 0.936 0.000
O70.0 First degree perineal laceration during delivery
0.064 0.936 0.000
O74 Complications of anaesthesia during labour and delivery
0.063 0.936 0.000
O66 Other obstructed labour
0.063 0.937 0.000
K12.1 Other forms of stomatitis
0.063 0.937 0.000
K12.2 Cellulitis and abscess of mouth
0.062 0.938 0.000
K07.9 Dentofacial anomaly, unspecified
0.062 0.938 0.000
K07.8 Other dentofacial anomalies
0.062 0.938 0.000
K07.5 Dentofacial functional abnormalities
0.062 0.938 0.000
K07.4 Malocclusion, unspecified
0.062 0.938 0.000
K07.2 Anomalies of dental arch relationship
0.062 0.938 0.000
K07.1 Anomalies of jaw-cranial base relationship
0.062 0.938 0.000
K07.0 Major anomalies of jaw size
0.062 0.938 0.000
K10 Other diseases of jaws
0.061 0.938 0.000
K03.9 Disease of hard tissues of teeth, unspecified
0.061 0.939 0.000
K03.8 Other specified diseases of hard tissues of teeth
0.061 0.939 0.000
K03.7 Posteruptive colour changes of dental hard tissues
0.061 0.939 0.000
K03.6 Deposits [accretions] on teeth
0.061 0.939 0.000
K03.5 Ankylosis of teeth
0.061 0.939 0.000
K03.4 Hypercementosis
0.061 0.939 0.000
K03.3 Pathological resorption of teeth
0.061 0.939 0.000
K03.2 Erosion of teeth
0.061 0.939 0.000
K03.1 Abrasion of teeth
0.061 0.939 0.000
K03.0 Excessive attrition of teeth
0.061 0.939 0.000
O63.9 Long labour, unspecified
0.061 0.939 0.000
O63.1 Prolonged second stage (of labour)
0.061 0.939 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.061 0.939 0.000
O62.2 Other uterine inertia
0.060 0.940 0.000
K12.0 Recurrent oral aphthae
0.060 0.940 0.000
K13.29 Other disturbances of oral epithelium, including tongue
0.060 0.940 0.000
O62.3 Precipitate labour
0.060 0.940 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.059 0.941 0.000
O61 Failed induction of labour
0.059 0.941 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.059 0.941 0.000
O72.1 Other immediate postpartum haemorrhage
0.059 0.941 0.000
O80-O84 Delivery
0.059 0.941 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.058 0.942 0.000
O73 Retained placenta and membranes, without haemorrhage
0.058 0.942 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.057 0.943 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.057 0.943 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.057 0.943 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.057 0.943 0.000
O60 Preterm delivery
0.057 0.943 0.000
K11.7 Disturbances of salivary secretion
0.057 0.943 0.000
K92.9 Disease of digestive system, unspecified
0.057 0.943 0.000
K07.3 Anomalies of tooth position
0.056 0.943 0.000
Chapter XI Diseases of the digestive system
0.056 0.944 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.055 0.945 0.000
O71.8 Other specified obstetric trauma
0.055 0.945 0.000
K11.9 Disease of salivary gland, unspecified
0.054 0.946 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.054 0.946 0.000
K93.1 Megacolon in Chagas' disease
0.054 0.946 0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.054 0.946 0.000
K92.8 Other specified diseases of digestive system
0.054 0.946 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.054 0.946 0.000
K01.1 Impacted teeth
0.054 0.946 0.000
O85-O92 Complications predominantly related to the puerperium
0.054 0.946 0.000
K01.0 Embedded teeth
0.053 0.947 0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery
0.052 0.948 0.000
Q60-Q64 Congenital malformations of the urinary system
0.052 0.948 0.000
O15 Eclampsia
0.052 0.948 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.052 0.948 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.052 0.948 0.000
Q61 Cystic kidney disease
0.052 0.948 0.000
O30 Multiple gestation
0.052 0.948 0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified
0.051 0.948 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.051 0.948 0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma
0.051 0.948 0.000
K06.1 Gingival enlargement
0.051 0.948 0.000
K06.0 Gingival recession
0.051 0.948 0.000
K02.8 Other dental caries
0.051 0.949 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.051 0.949 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.051 0.949 0.000
O82 Single delivery by Caesarean section
0.051 0.949 0.000
O62.9 Abnormality of forces of labour, unspecified
0.051 0.949 0.000
O62.8 Other abnormalities of forces of labour
0.051 0.949 0.000
O62.1 Secondary uterine inertia
0.051 0.949 0.000
O62.0 Primary inadequate contractions
0.051 0.949 0.000
K11.4 Fistula of salivary gland
0.051 0.949 0.000
K11.3 Abscess of salivary gland
0.051 0.949 0.000
K11.0 Atrophy of salivary gland
0.051 0.949 0.000
O72.3 Postpartum coagulation defects
0.050 0.949 0.000
K11.1 Hypertrophy of salivary gland
0.050 0.949 0.000
O36 Maternal care for other known or suspected foetal problems
0.050 0.950 0.000
O21 Excessive vomiting in pregnancy
0.049 0.951 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.049 0.951 0.000
K02.5 Caries with pulp exposure
0.049 0.951 0.000
K02.4 Odontoclasia
0.049 0.951 0.000
K02.3 Arrested dental caries
0.049 0.951 0.000
K02.2 Caries of cementum
0.049 0.951 0.000
K02.1 Caries of dentin
0.049 0.951 0.000
K02.0 Caries limited to enamel
0.049 0.951 0.000
O81 Single delivery by forceps and vacuum extractor
0.049 0.951 0.000
Q61.3 Polycystic kidney, unspecified
0.049 0.951 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.048 0.951 0.000
O70.3 Fourth degree perineal laceration during delivery
0.048 0.952 0.000
K05.22 Aggressive periodontitis, generalized
0.048 0.952 0.000
O30.0 Twin pregnancy
0.048 0.952 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.048 0.952 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.048 0.952 0.000
O72.0 Third-stage haemorrhage
0.047 0.952 0.000
Q61.2 Polycystic kidney, adult type
0.047 0.953 0.000
O23 Infections of genito-urinary tract in pregnancy
0.047 0.953 0.000
O66.0 Obstructed labour due to shoulder dystocia
0.047 0.953 0.000
K11.8 Other diseases of salivary glands
0.047 0.953 0.000
O71.9 Obstetric trauma, unspecified
0.047 0.953 0.000
O71.7 Obstetric haematoma of pelvis
0.047 0.953 0.000
O71.6 Obstetric damage to pelvic joints and ligaments
0.047 0.953 0.000
O71.5 Other obstetric injury to pelvic organs
0.047 0.953 0.000
O71.4 Obstetric high vaginal laceration alone
0.047 0.953 0.000
O71.3 Obstetric laceration of cervix
0.047 0.953 0.000
O71.2 Postpartum inversion of uterus
0.047 0.953 0.000
O71.1 Rupture of uterus during labour
0.047 0.953 0.000
O71.0 Rupture of uterus before onset of labour
0.047 0.953 0.000
O70.9 Perineal laceration during delivery, unspecified
0.047 0.953 0.000
O40 Polyhydramnios
0.046 0.954 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.046 0.954 0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified
0.046 0.954 0.000
O74.8 Other complications of anaesthesia during labour and delivery
0.046 0.954 0.000
O74.7 Failed or difficult intubation during labour and delivery
0.046 0.954 0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery
0.046 0.954 0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery
0.046 0.954 0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery
0.046 0.954 0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery
0.046 0.954 0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery
0.046 0.954 0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery
0.046 0.954 0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage
0.046 0.954 0.000
K11.2 Sialoadenitis
0.046 0.954 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.046 0.954 0.000
O14.9 Preeclampsia, unspecified
0.045 0.954 0.000
O61.0 Failed medical induction of labour
0.045 0.955 0.000
O66.9 Obstructed labour, unspecified
0.045 0.955 0.000
O66.8 Other specified obstructed labour
0.045 0.955 0.000
O66.4 Failed trial of labour, unspecified
0.045 0.955 0.000
O66.3 Obstructed labour due to other abnormalities of foetus
0.045 0.955 0.000
O66.2 Obstructed labour due to unusually large foetus
0.045 0.955 0.000
O66.1 Obstructed labour due to locked twins
0.045 0.955 0.000
O70.2 Third degree perineal laceration during delivery
0.045 0.955 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.045 0.955 0.000
O12.1 Gestational proteinuria
0.045 0.955 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.045 0.955 0.000
K11.5 Sialolithiasis
0.045 0.955 0.000
K10.9 Disease of jaws, unspecified
0.044 0.955 0.000
K10.3 Alveolitis of jaws
0.044 0.955 0.000
K10.1 Giant cell granuloma, central
0.044 0.955 0.000
K10.0 Developmental disorders of jaws
0.044 0.955 0.000
O36.5 Maternal care for poor foetal growth
0.044 0.956 0.000
O28 Abnormal findings on antenatal screening of mother
0.044 0.956 0.000
O87 Venous complications in the puerperium
0.044 0.956 0.000
Q80-Q89 Other congenital malformations
0.044 0.956 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.043 0.957 0.000
O43 Placental disorders
0.043 0.957 0.000
Q23 Congenital malformations of aortic and mitral valves
0.043 0.957 0.000
K65-K67 Diseases of peritoneum
0.043 0.957 0.000
O82.1 Delivery by emergency Caesarean section
0.043 0.957 0.000
O29 Complications of anaesthesia during pregnancy
0.043 0.957 0.000
O22 Venous complications in pregnancy
0.043 0.957 0.000
O25 Malnutrition in pregnancy
0.043 0.957 0.000
O61.9 Failed induction of labour, unspecified
0.043 0.957 0.000
O61.8 Other failed induction of labour
0.043 0.957 0.000
O61.1 Failed instrumental induction of labour
0.043 0.957 0.000
K11.6 Mucocele of salivary gland
0.042 0.957 0.000
O12.0 Gestational oedema
0.042 0.958 0.000
O84 Multiple delivery
0.042 0.958 0.000
O83 Other assisted single delivery
0.042 0.958 0.000
O36.9 Maternal care for foetal problem, unspecified
0.042 0.958 0.000
O21.0 Mild hyperemesis gravidarum
0.042 0.958 0.000
O67.8 Other intrapartum haemorrhage
0.042 0.958 0.000
O67.0 Intrapartum haemorrhage with coagulation defect
0.042 0.958 0.000
K40-K46 Hernia
0.042 0.958 0.000
O41 Other disorders of amniotic fluid and membranes
0.042 0.958 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.041 0.959 0.000
O45 Premature separation of placenta [abruptio placentae]
0.041 0.959 0.000
O33 Maternal care for known or suspected disproportion
0.041 0.959 0.000
O31 Complications specific to multiple gestation
0.041 0.959 0.000
O12.2 Gestational oedema with proteinuria
0.041 0.959 0.000
O60.3 Preterm delivery without spontaneous labour
0.041 0.959 0.000
O60.2 Preterm spontaneous labour with term delivery
0.041 0.959 0.000
O60.1 Preterm spontaneous labour with preterm delivery
0.041 0.959 0.000
O60.0 Preterm labour without delivery
0.041 0.959 0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified
0.041 0.959 0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities
0.041 0.959 0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs
0.041 0.959 0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified
0.041 0.959 0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction
0.041 0.959 0.000
O65.2 Obstructed labour due to pelvic inlet contraction
0.041 0.959 0.000
O65.1 Obstructed labour due to generally contracted pelvis
0.041 0.959 0.000
O65.0 Obstructed labour due to deformed pelvis
0.041 0.959 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.041 0.959 0.000
O48 Prolonged pregnancy
0.041 0.959 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.041 0.959 0.000
H65-H75 Diseases of middle ear and mastoid
0.041 0.959 0.000
K92.0 Haematemesis
0.041 0.959 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.041 0.959 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.041 0.959 0.000
Q18 Other congenital malformations of face and neck
0.041 0.959 0.000
Q27 Other congenital malformations of peripheral vascular system
0.040 0.960 0.000
O24 Diabetes mellitus in pregnancy
0.040 0.960 0.000
O82.9 Delivery by Caesarean section, unspecified
0.040 0.960 0.000
Q61.0 Congenital single renal cyst
0.040 0.960 0.000
Q63 Other congenital malformations of kidney
0.040 0.960 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.040 0.960 0.000
K43 Ventral hernia
0.040 0.960 0.000
O23.4 Unspecified infection of urinary tract in pregnancy
0.040 0.960 0.000
O14.2 HELLP syndrome
0.039 0.960 0.000
Q23.1 Congenital insufficiency of aortic valve
0.039 0.961 0.000
O81.0 Low forceps delivery
0.039 0.961 0.000
H65 Nonsuppurative otitis media
0.039 0.961 0.000
O47 False labour
0.039 0.961 0.000
O82.0 Delivery by elective Caesarean section
0.039 0.961 0.000
O92 Other disorders of breast and lactation associated with childbirth
0.039 0.961 0.000
O91 Infections of breast associated with childbirth
0.039 0.961 0.000
O89 Complications of anaesthesia during the puerperium
0.039 0.961 0.000
O88 Obstetric embolism
0.039 0.961 0.000
O85 Puerperal sepsis
0.039 0.961 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.039 0.961 0.000
K10.2 Inflammatory conditions of jaws
0.038 0.961 0.000
O81.4 Vacuum extractor delivery
0.038 0.961 0.000
O73.0 Retained placenta, without haemorrhage
0.038 0.961 0.000
Chapter VIII Diseases of the ear and mastoid process
0.038 0.962 0.000
O14.1 Severe preeclampsia
0.038 0.962 0.000
K66 Other disorders of peritoneum
0.038 0.962 0.000
Q50-Q56 Congenital malformations of genital organs
0.038 0.962 0.000
O26.2 Pregnancy care of habitual aborter
0.038 0.962 0.000
Q64 Other congenital malformations of urinary system
0.038 0.962 0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.038 0.962 0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium
0.038 0.962 0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium
0.038 0.962 0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium
0.038 0.962 0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium
0.038 0.962 0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.038 0.962 0.000
O15.9 Eclampsia, unspecified as to time period
0.038 0.962 0.000
O15.2 Eclampsia in the puerperium
0.038 0.962 0.000
O15.1 Eclampsia in labour
0.038 0.962 0.000
O15.0 Eclampsia in pregnancy
0.038 0.962 0.000
Q61.9 Cystic kidney disease, unspecified
0.038 0.962 0.000
Q61.8 Other cystic kidney diseases
0.038 0.962 0.000
Q61.5 Medullary cystic kidney
0.038 0.962 0.000
Q61.4 Renal dysplasia
0.038 0.962 0.000
Q61.1 Polycystic kidney, infantile type
0.038 0.962 0.000
Q18.0 Sinus, fistula and cyst of branchial cleft
0.037 0.962 0.000
O87.2 Haemorrhoids in the puerperium
0.037 0.962 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.037 0.963 0.000
O30.9 Multiple gestation, unspecified
0.037 0.963 0.000
O30.8 Other multiple gestation
0.037 0.963 0.000
O30.2 Quadruplet pregnancy
0.037 0.963 0.000
O30.1 Triplet pregnancy
0.037 0.963 0.000
Q24 Other congenital malformations of heart
0.037 0.963 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.037 0.963 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.037 0.963 0.000
O64.5 Obstructed labour due to compound presentation
0.037 0.963 0.000
O64.4 Obstructed labour due to shoulder presentation
0.037 0.963 0.000
O64.3 Obstructed labour due to brow presentation
0.037 0.963 0.000
O64.2 Obstructed labour due to face presentation
0.037 0.963 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.037 0.963 0.000
Q35-Q37 Cleft lip and cleft palate
0.037 0.963 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.037 0.963 0.000
O44 Placenta praevia
0.037 0.963 0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.037 0.963 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.037 0.963 0.000
O82.8 Other single delivery by Caesarean section
0.037 0.963 0.000
O82.2 Delivery by Caesarean hysterectomy
0.037 0.963 0.000
O69.8 Labour and delivery complicated by other cord complications
0.037 0.963 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.037 0.963 0.000
O14.0 Moderate preeclampsia
0.036 0.964 0.000
O64.1 Obstructed labour due to breech presentation
0.036 0.964 0.000
Q82 Other congenital malformations of skin
0.036 0.964 0.000
K41 Femoral hernia
0.036 0.964 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.036 0.964 0.000
O36.4 Maternal care for intra-uterine death
0.036 0.964 0.000
O36.2 Maternal care for hydrops foetalis
0.036 0.964 0.000
O36.1 Maternal care for other isoimmunisation
0.036 0.964 0.000
O00-O08 Pregnancy with abortive outcome
0.036 0.964 0.000
O90 Complications of the puerperium, not elsewhere classified
0.036 0.964 0.000
H72 Perforation of tympanic membrane
0.036 0.964 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.036 0.964 0.000
O21.9 Vomiting of pregnancy, unspecified
0.035 0.964 0.000
O21.8 Other vomiting complicating pregnancy
0.035 0.964 0.000
O21.2 Late vomiting of pregnancy
0.035 0.964 0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.035 0.964 0.000
K66.8 Other specified disorders of peritoneum
0.036 0.964 0.000
C67.9 Bladder, unspecified
0.036 0.964 0.000
Q21 Congenital malformations of cardiac septa
0.035 0.965 0.000
Q89 Other congenital malformations, not elsewhere classified
0.035 0.965 0.000
O81.5 Delivery by combination of forceps and vacuum extractor
0.035 0.965 0.000
O81.3 Other and unspecified forceps delivery
0.035 0.965 0.000
O81.2 Mid-cavity forceps with rotation
0.035 0.965 0.000
O81.1 Mid-cavity forceps delivery
0.035 0.965 0.000
Q27.8 Other specified congenital malformations of peripheral vascular system
0.035 0.965 0.000
O86 Other puerperal infections
0.035 0.965 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.035 0.965 0.000
O97 Death from sequelae of direct obstetric causes
0.035 0.965 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.035 0.965 0.000
O95 Obstetric death of unspecified cause
0.035 0.965 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.035 0.965 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.035 0.965 0.000
H65.4 Other chronic nonsuppurative otitis media
0.035 0.965 0.000
O41.0 Oligohydramnios
0.035 0.965 0.000
Q26 Congenital malformations of great veins
0.034 0.965 0.000
Q25 Congenital malformations of great arteries
0.034 0.965 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.034 0.965 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.034 0.965 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.035 0.965 0.000
O46.9 Antepartum haemorrhage, unspecified
0.034 0.966 0.000
O46.8 Other antepartum haemorrhage
0.034 0.966 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.034 0.966 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.034 0.966 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.034 0.966 0.000
O69.3 Labour and delivery complicated by short cord
0.034 0.966 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.034 0.966 0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.034 0.966 0.000
O23.3 Infections of other parts of urinary tract in pregnancy
0.034 0.966 0.000
O23.2 Infections of urethra in pregnancy
0.034 0.966 0.000
O23.1 Infections of bladder in pregnancy
0.034 0.966 0.000
O23.0 Infections of kidney in pregnancy
0.034 0.966 0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.034 0.966 0.000
H74 Other disorders of middle ear and mastoid
0.034 0.966 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.034 0.966 0.000
O43.8 Other placental disorders
0.034 0.966 0.000
Q00-Q07 Congenital malformations of the nervous system
0.034 0.966 0.000
C67 Malignant neoplasm of bladder
0.034 0.966 0.000
K45 Other abdominal hernia
0.033 0.966 0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother
0.033 0.966 0.000
K05.3 Chronic periodontitis
0.033 0.967 0.000
O70.1 Second degree perineal laceration during delivery
0.033 0.967 0.000
H60-H62 Diseases of external ear
0.033 0.967 0.000
Q43 Other congenital malformations of intestine
0.033 0.967 0.000
H72.0 Central perforation of tympanic membrane
0.033 0.967 0.000
O20 Haemorrhage in early pregnancy
0.033 0.967 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.033 0.967 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.033 0.967 0.000
O26.5 Maternal hypotension syndrome
0.033 0.967 0.000
O26.4 Herpes gestationis
0.033 0.967 0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.033 0.967 0.000
O26.1 Low weight gain in pregnancy
0.033 0.967 0.000
O26.0 Excessive weight gain in pregnancy
0.033 0.967 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.033 0.967 0.000
Q23.0 Congenital stenosis of aortic valve
0.033 0.967 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.033 0.967 0.000
Q12 Congenital lens malformations
0.033 0.967 0.000
Q60.0 Renal agenesis, unilateral
0.033 0.967 0.000
H71 Cholesteatoma of middle ear
0.033 0.967 0.000
Q17 Other congenital malformations of ear
0.032 0.967 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.032 0.967 0.000
Q15 Other congenital malformations of eye
0.032 0.967 0.000
Q14 Congenital malformations of posterior segment of eye
0.032 0.967 0.000
Q13 Congenital malformations of anterior segment of eye
0.032 0.967 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.032 0.967 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.032 0.967 0.000
O23.5 Infections of the genital tract in pregnancy
0.032 0.967 0.000
O46.0 Antepartum haemorrhage with coagulation defect
0.032 0.967 0.000
Q62.5 Duplication of ureter
0.032 0.968 0.000
H60 Otitis externa
0.032 0.968 0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified
0.032 0.968 0.000
O28.8 Other abnormal findings on antenatal screening of mother
0.032 0.968 0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother
0.032 0.968 0.000
O28.4 Abnormal radiological finding on antenatal screening of mother
0.032 0.968 0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother
0.032 0.968 0.000
O28.2 Abnormal cytological finding on antenatal screening of mother
0.032 0.968 0.000
O28.0 Abnormal haematological finding on antenatal screening of mother
0.032 0.968 0.000
O87.9 Venous complication in the puerperium, unspecified
0.032 0.968 0.000
O87.8 Other venous complications in the puerperium
0.032 0.968 0.000
O87.3 Cerebral venous thrombosis in the puerperium
0.032 0.968 0.000
O87.1 Deep phlebothrombosis in the puerperium
0.032 0.968 0.000
O87.0 Superficial thrombophlebitis in the puerperium
0.032 0.968 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.032 0.968 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.032 0.968 0.000
Q84 Other congenital malformations of integument
0.032 0.968 0.000
Q83 Congenital malformations of breast
0.032 0.968 0.000
Q81 Epidermolysis bullosa
0.032 0.968 0.000
Q80 Congenital ichthyosis
0.032 0.968 0.000
H66 Suppurative and unspecified otitis media
0.032 0.968 0.000
O43.9 Placental disorder, unspecified
0.031 0.969 0.000
O43.2 Morbidly adherent placenta
0.031 0.969 0.000
O43.0 Placental transfusion syndromes
0.031 0.969 0.000
H90-H95 Other disorders of ear
0.031 0.969 0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified
0.031 0.969 0.000
Q23.8 Other congenital malformations of aortic and mitral valves
0.031 0.969 0.000
Q23.4 Hypoplastic left heart syndrome
0.031 0.969 0.000
Q23.3 Congenital mitral insufficiency
0.031 0.969 0.000
Q23.2 Congenital mitral stenosis
0.031 0.969 0.000
Q85 Phakomatoses, not elsewhere classified
0.031 0.969 0.000
K10.8 Other specified diseases of jaws
0.031 0.969 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.031 0.969 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.031 0.969 0.000
O22.9 Venous complication in pregnancy, unspecified
0.031 0.969 0.000
O22.8 Other venous complications in pregnancy
0.031 0.969 0.000
O22.5 Cerebral venous thrombosis in pregnancy
0.031 0.969 0.000
O22.4 Haemorrhoids in pregnancy
0.031 0.969 0.000
O22.3 Deep phlebothrombosis in pregnancy
0.031 0.969 0.000
O22.2 Superficial thrombophlebitis in pregnancy
0.031 0.969 0.000
O22.1 Genital varices in pregnancy
0.031 0.969 0.000
O22.0 Varicose veins of lower extremity in pregnancy
0.031 0.969 0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified
0.031 0.969 0.000
O29.8 Other complications of anaesthesia during pregnancy
0.031 0.969 0.000
O29.6 Failed or difficult intubation during pregnancy
0.031 0.969 0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy
0.031 0.969 0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy
0.031 0.969 0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy
0.031 0.969 0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy
0.031 0.969 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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