TreeWAS – Variant ID: rs224333

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.000	1.000
M17.9 Gonarthrosis, unspecified	0.000	0.000	1.000
M20.1 Hallux valgus (acquired)	0.000	0.000	1.000
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.000	1.000
M23 Internal derangement of knee	0.000	0.000	1.000
M17 Gonarthrosis [arthrosis of knee]	0.000	0.000	1.000
M17.1 Other primary gonarthrosis	0.000	0.001	0.999
M20 Acquired deformities of fingers and toes	0.000	0.001	0.999
M20-M25 Other joint disorders	0.000	0.002	0.998
M23.3 Other meniscus derangements	0.000	0.003	0.997
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.009	0.991
M20.5 Other deformities of toe(s) (acquired)	0.000	0.011	0.989
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.019	0.981
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.019	0.981
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.023	0.977
M17.0 Primary gonarthrosis, bilateral	0.000	0.037	0.963
K44.9 Diaphragmatic hernia without obstruction or gangrene	0.000	0.045	0.955
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.046	0.954
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.056	0.944
M24 Other specific joint derangements	0.000	0.091	0.909
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.096	0.904
M23.8 Other internal derangements of knee	0.000	0.098	0.902
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.098	0.902
M23.4 Loose body in knee	0.000	0.103	0.897
M17.3 Other posttraumatic gonarthrosis	0.000	0.109	0.891
R59.1 Generalised enlarged lymph nodes	0.882	0.118	0.000
R59.0 Localised enlarged lymph nodes	0.876	0.124	0.000
M24.1 Other articular cartilage disorders	0.000	0.124	0.876
R59 Enlarged lymph nodes	0.874	0.126	0.000
M22 Disorders of patella	0.000	0.142	0.858
M23.49 Loose body in knee-Unspec lig/men	0.000	0.145	0.855
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.000	0.146	0.854
M21 Other acquired deformities of limbs	0.000	0.157	0.843
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.163	0.837
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.164	0.836
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.181	0.819
M21.1 Varus deformity, not elsewhere classified	0.000	0.188	0.812
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.191	0.809
M23.0 Cystic meniscus	0.000	0.203	0.797
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.205	0.795
M23.30 Other meniscus derangements (Multiple sites)	0.000	0.209	0.791
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.000	0.210	0.790
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.224	0.776
M23.46 Loose body in knee-O/unsp lat men	0.000	0.228	0.772
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.000	0.228	0.772
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.000	0.243	0.757
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.252	0.748
M23.80 Other internal derangements of knee (Multiple sites)	0.000	0.256	0.744
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.261	0.739
M24.6 Ankylosis of joint	0.000	0.270	0.730
M17.5 Other secondary gonarthrosis	0.000	0.281	0.719
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.283	0.717
M23.37 Other meniscus derangements-Capsular lig	0.000	0.285	0.715
M33 Dermatopolymyositis	0.000	0.288	0.712
M23.1 Discoid meniscus (congenital)	0.000	0.290	0.710
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.297	0.703
M20.0 Deformity of finger(s)	0.000	0.299	0.701
M17.4 Other secondary gonarthrosis, bilateral	0.000	0.300	0.700
M21.4 Flat foot [pes planus] (acquired)	0.000	0.301	0.699
M22.0 Recurrent dislocation of patella	0.000	0.302	0.698
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.306	0.694
M22.2 Patellofemoral disorders	0.000	0.308	0.692
M22.3 Other derangements of patella	0.000	0.308	0.692
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.312	0.688
M17.2 Posttraumatic gonarthrosis, bilateral	0.000	0.320	0.680
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.000	0.324	0.676
M20.3 Other deformity of hallux (acquired)	0.000	0.335	0.665
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.336	0.664
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.000	0.340	0.659
M23.40 Loose body in knee-Mult sites	0.000	0.344	0.655
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.348	0.652
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.353	0.647
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.353	0.647
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.353	0.647
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.000	0.356	0.644
M23.47 Loose body in knee-Capsular lig	0.000	0.357	0.643
M23.45 Loose body in knee-Pst hrn lat men	0.000	0.357	0.643
M23.42 Loose body in knee-Pst lig/hrn men	0.000	0.357	0.643
M21.6 Other acquired deformities of ankle and foot	0.000	0.358	0.642
M24.9 Joint derangement, unspecified	0.000	0.360	0.640
M32 Systemic lupus erythematosus	0.000	0.363	0.637
M23.5 Chronic instability of knee	0.000	0.367	0.633
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.368	0.632
M22.9 Disorder of patella, unspecified	0.000	0.371	0.629
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.372	0.628
M24.18 Other articular cartilage disorders (Other)	0.000	0.372	0.628
M24.14 Other articular cartilage disorders (Hand)	0.000	0.372	0.628
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.372	0.628
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.372	0.628
M24.7 Protrusio acetabuli	0.000	0.374	0.626
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.377	0.623
M24.5 Contracture of joint	0.000	0.383	0.617
M22.1 Recurrent subluxation of patella	0.000	0.385	0.615
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.385	0.615
M23.9 Internal derangement of knee, unspecified	0.000	0.389	0.611
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.000	0.389	0.611
M21.9 Acquired deformity of limb, unspecified	0.000	0.391	0.608
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.000	0.405	0.595
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.405	0.595
M24.66 Ankylosis of joint (Lower leg)	0.000	0.407	0.593
M21.3 Wrist or foot drop (acquired)	0.000	0.409	0.591
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.414	0.586
M22.8 Other disorders of patella	0.000	0.416	0.584
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.000	0.418	0.582
M21.18 Varus deformity, not elsewhere classified (Other)	0.000	0.418	0.582
M21.14 Varus deformity, not elsewhere classified (Hand)	0.000	0.418	0.582
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.000	0.418	0.582
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.000	0.418	0.582
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.000	0.418	0.582
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.000	0.418	0.582
M33.1 Other dermatomyositis	0.000	0.418	0.582
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.419	0.581
R59.9 Enlarged lymph nodes, unspecified	0.576	0.424	0.000
M23.07 Cystic meniscus-Capsular lig	0.000	0.428	0.571
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.000	0.428	0.571
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.428	0.571
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.428	0.571
M23.00 Cystic meniscus (Multiple sites)	0.000	0.428	0.571
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.430	0.570
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.430	0.570
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.433	0.567
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.000	0.434	0.566
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.442	0.558
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.443	0.557
M22.4 Chondromalacia patellae	0.000	0.443	0.557
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.000	0.446	0.554
M36.3 Arthropathy in other blood disorders	0.000	0.446	0.554
M36.2 Haemophilic arthropathy	0.000	0.446	0.554
M36.1 Arthropathy in neoplastic disease	0.000	0.446	0.554
M36.0 Dermato(poly)myositis in neoplastic disease	0.000	0.446	0.554
M23.43 Loose body in knee-Med lig/oth men	0.000	0.453	0.547
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.455	0.544
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.456	0.544
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.464	0.536
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.464	0.536
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.464	0.536
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.464	0.536
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.464	0.536
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.464	0.536
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.464	0.536
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.464	0.536
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.464	0.536
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.467	0.533
M21.8 Other specified acquired deformities of limbs	0.000	0.471	0.529
M30 Polyarteritis nodosa and related conditions	0.000	0.474	0.526
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.477	0.523
M24.68 Ankylosis of joint (Other)	0.000	0.477	0.523
M24.63 Ankylosis of joint (Forearm)	0.000	0.477	0.523
M24.62 Ankylosis of joint (Upper arm)	0.000	0.477	0.523
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.477	0.523
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.477	0.523
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.481	0.518
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.485	0.515
M23.44 Loose body in knee-Lat lig/ant men	0.000	0.488	0.512
M33.9 Dermatopolymyositis, unspecified	0.000	0.490	0.510
M33.0 Juvenile dermatomyositis	0.000	0.490	0.510
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.000	0.491	0.509
M23.17 Discoid meniscus (congenital)-Capsular lig	0.000	0.491	0.509
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.000	0.491	0.509
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.491	0.509
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.491	0.509
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.491	0.509
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.491	0.509
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.000	0.491	0.509
M24.64 Ankylosis of joint (Hand)	0.000	0.495	0.504
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.000	0.498	0.502
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.000	0.499	0.501
M21.48 Flat foot [pes planus] (acquired)-Other	0.000	0.499	0.501
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.000	0.499	0.501
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.000	0.499	0.501
M21.44 Flat foot [pes planus] (acquired)-Hand	0.000	0.499	0.501
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.000	0.499	0.501
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.000	0.499	0.501
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.000	0.499	0.501
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.000	0.499	0.501
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.499	0.501
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.500	0.500
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.501	0.499
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.000	0.501	0.499
M24.56 Contracture of joint (Lower leg)	0.000	0.519	0.481
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.524	0.476
M32.8 Other forms of systemic lupus erythematosus	0.000	0.534	0.465
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.000	0.538	0.461
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.000	0.538	0.461
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.000	0.538	0.461
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.000	0.538	0.461
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.000	0.538	0.461
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.000	0.538	0.461
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.000	0.538	0.461
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.000	0.538	0.461
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.000	0.538	0.461
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.000	0.539	0.461
M21.68 Other acquired deformities of ankle and foot-Other	0.000	0.539	0.461
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.000	0.539	0.461
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.000	0.539	0.461
M21.64 Other acquired deformities of ankle and foot-Hand	0.000	0.539	0.461
M21.63 Other acquired deformities of ankle and foot-Forearm	0.000	0.539	0.461
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.000	0.539	0.461
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.000	0.539	0.461
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.000	0.539	0.461
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.541	0.459
M24.98 Joint derangement, unspecified (Other)	0.000	0.541	0.459
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.541	0.459
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.541	0.459
M24.94 Joint derangement, unspecified (Hand)	0.000	0.541	0.459
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.541	0.459
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.541	0.459
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.541	0.459
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.541	0.459
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.542	0.458
M32.9 Systemic lupus erythematosus, unspecified	0.000	0.543	0.457
M32.0 Drug-induced systemic lupus erythematosus	0.000	0.543	0.457
M23.57 Chronic instability of knee (Capsular ligament)	0.000	0.546	0.454
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.000	0.546	0.454
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.000	0.546	0.454
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.546	0.454
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.546	0.454
M23.50 Chronic instability of knee (Multiple sites)	0.000	0.546	0.454
M24.2 Disorder of ligament	0.000	0.547	0.453
M24.52 Contracture of joint (Upper arm)	0.000	0.549	0.451
M23.41 Loose body in knee-Ant lig/hrn men	0.001	0.550	0.449
M24.79 Protrusio acetabuli-Site unspec	0.000	0.551	0.449
M24.78 Protrusio acetabuli-Other	0.000	0.551	0.449
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.551	0.449
M24.76 Protrusio acetabuli-Lower leg	0.000	0.551	0.449
M24.74 Protrusio acetabuli-Hand	0.000	0.551	0.449
M24.73 Protrusio acetabuli-Forearm	0.000	0.551	0.449
M24.72 Protrusio acetabuli-Upper arm	0.000	0.551	0.449
M24.71 Protrusio acetabuli-Shldr region	0.000	0.551	0.449
M24.70 Protrusio acetabuli-Mult sites	0.000	0.551	0.449
M34 Systemic sclerosis	0.000	0.553	0.447
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.553	0.447
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.553	0.446
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.553	0.446
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.553	0.446
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.553	0.446
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.553	0.446
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.553	0.446
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.553	0.446
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.553	0.446
M24.57 Contracture of joint (Ankle and foot)	0.000	0.557	0.443
M24.59 Contracture of joint (Site unspecified)	0.000	0.557	0.443
M24.58 Contracture of joint (Other)	0.000	0.557	0.443
M24.53 Contracture of joint (Forearm)	0.000	0.557	0.443
M24.50 Contracture of joint (Multiple sites)	0.000	0.557	0.443
M21.0 Valgus deformity, not elsewhere classified	0.000	0.558	0.442
M22.10 Recurrent subluxation of patella, unspecified knee	0.000	0.559	0.441
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.000	0.559	0.440
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.000	0.562	0.438
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.000	0.562	0.438
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.000	0.562	0.438
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.562	0.438
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.562	0.438
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.562	0.438
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.000	0.562	0.438
M24.55 Contracture of joint (Pelvic region and thigh)	0.000	0.562	0.438
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.000	0.563	0.436
M21.98 Acquired deformity of limb, unspecified-Other	0.000	0.563	0.436
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.000	0.563	0.436
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.000	0.563	0.436
M21.94 Acquired deformity of limb, unspecified (Hand)	0.000	0.563	0.436
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.000	0.563	0.436
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.000	0.563	0.436
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.000	0.563	0.436
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.000	0.563	0.436
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.575	0.424
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.576	0.424
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.576	0.424
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.576	0.424
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.576	0.424
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.576	0.424
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.576	0.424
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.576	0.424
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.576	0.424
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.576	0.424
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.577	0.423
M24.51 Contracture of joint (Shoulder region)	0.000	0.578	0.422
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.000	0.587	0.413
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.590	0.410
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.000	0.593	0.406
M21.2 Flexion deformity	0.000	0.595	0.404
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.597	0.402
M20.4 Other hammer toe(s) (acquired)	0.000	0.604	0.396
M33.2 Polymyositis	0.000	0.606	0.393
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.000	0.617	0.382
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.618	0.382
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.000	0.620	0.379
M21.88 Other specified acquired deformities of limbs-Other	0.000	0.620	0.379
M21.84 Other specified acquired deformities of limbs (Hand)	0.000	0.620	0.379
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.000	0.620	0.379
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.000	0.620	0.379
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.000	0.620	0.379
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.001	0.621	0.378
M30.8 Other conditions related to polyarteritis nodosa	0.000	0.623	0.377
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.000	0.623	0.377
M30.2 Juvenile polyarteritis	0.000	0.623	0.377
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.001	0.623	0.376
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.626	0.373
M24.54 Contracture of joint (Hand)	0.000	0.627	0.373
M21.7 Unequal limb length (acquired)	0.001	0.627	0.372
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.632	0.368
M21.83 Other specified acquired deformities of limbs (Forearm)	0.000	0.634	0.366
M24.23 Disorder of ligament (Forearm)	0.000	0.634	0.366
M32.1 Systemic lupus erythematosus with organ or system involvement	0.000	0.635	0.365
M24.24 Disorder of ligament (Hand)	0.000	0.638	0.361
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.648	0.352
M21.27 Flexion deformity (Ankle and foot)	0.000	0.654	0.346
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.659	0.341
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.659	0.341
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.659	0.341
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.659	0.341
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.659	0.341
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.659	0.341
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.000	0.672	0.327
M24.29 Disorder of ligament (Site unspecified)	0.000	0.675	0.325
M24.22 Disorder of ligament (Upper arm)	0.000	0.675	0.325
M24.20 Disorder of ligament (Multiple sites)	0.000	0.675	0.325
M34.2 Systemic sclerosis induced by drugs and chemicals	0.000	0.679	0.321
M24.26 Disorder of ligament (Lower leg)	0.000	0.680	0.319
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.000	0.683	0.317
M21.08 Valgus deformity, not elsewhere classified (Other)	0.000	0.683	0.317
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.000	0.683	0.317
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.000	0.683	0.317
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.000	0.683	0.317
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.000	0.683	0.317
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.000	0.683	0.317
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.000	0.683	0.317
K44 Diaphragmatic hernia	0.000	0.684	0.316
M30.0 Polyarteritis nodosa	0.000	0.689	0.310
M25 Other joint disorders, not elsewhere classified	0.000	0.693	0.307
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.695	0.305
M34.1 CR(E)ST syndrome	0.000	0.705	0.295
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.707	0.293
M34.0 Progressive systemic sclerosis	0.000	0.707	0.292
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.708	0.291
M21.29 Flexion deformity (Site unspecified)	0.000	0.710	0.290
M21.28 Flexion deformity (Other)	0.000	0.710	0.290
M21.23 Flexion deformity (Forearm)	0.000	0.710	0.290
M21.22 Flexion deformity (Upper arm)	0.000	0.710	0.290
M21.21 Flexion deformity (Shoulder region)	0.000	0.710	0.290
M21.20 Flexion deformity (Multiple sites)	0.000	0.710	0.290
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.718	0.281
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.721	0.278
M65.34 Trigger finger-Hand	0.000	0.722	0.278
M25.76 Osteophyte (Lower leg)	0.000	0.724	0.276
M25.7 Osteophyte	0.000	0.727	0.273
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.001	0.728	0.271
M34.9 Systemic sclerosis, unspecified	0.000	0.731	0.269
M21.79 Unequal limb length (acquired) (Site unspecified)	0.001	0.732	0.267
M21.78 Unequal limb length (acquired)-Other	0.001	0.732	0.267
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.001	0.732	0.267
M21.74 Unequal limb length (acquired) (Hand)	0.001	0.732	0.267
M21.72 Unequal limb length (acquired) (Upper arm)	0.001	0.732	0.267
M21.71 Unequal limb length (acquired)-Shldr region	0.001	0.732	0.267
M21.70 Unequal limb length (acquired) (Multiple sites)	0.001	0.732	0.267
M24.28 Disorder of ligament (Other)	0.000	0.733	0.267
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.742	0.258
M34.8 Other forms of systemic sclerosis	0.000	0.743	0.257
M25.3 Other instability of joint	0.000	0.743	0.257
M24.0 Loose body in joint	0.001	0.748	0.251
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.754	0.246
M25.34 Other instability of joint (Hand)	0.000	0.762	0.238
M65.3 Trigger finger	0.000	0.762	0.238
M15-M19 Arthrosis	0.000	0.763	0.237
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.001	0.763	0.236
M25.72 Osteophyte (Upper arm)	0.000	0.769	0.231
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.001	0.771	0.228
M25.56 Pain in joint (Lower leg)	0.000	0.777	0.223
M25.2 Flail joint	0.000	0.779	0.220
M25.1 Fistula of joint	0.000	0.779	0.220
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.780	0.220
M25.8 Other specified joint disorders	0.000	0.780	0.220
M21.24 Flexion deformity (Hand)	0.001	0.781	0.219
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.000	0.784	0.216
M21.73 Unequal limb length (acquired) (Forearm)	0.001	0.787	0.212
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.788	0.212
M21.76 Unequal limb length (acquired) (Lower leg)	0.001	0.788	0.211
M65-M68 Disorders of synovium and tendon	0.000	0.789	0.211
M65 Synovitis and tenosynovitis	0.000	0.792	0.208
M25.0 Haemarthrosis	0.000	0.796	0.204
M25.74 Osteophyte (Hand)	0.000	0.800	0.200
M21.26 Flexion deformity (Lower leg)	0.001	0.802	0.198
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.803	0.196
M25.70 Osteophyte (Multiple sites)	0.000	0.804	0.196
M25.73 Osteophyte (Forearm)	0.000	0.807	0.193
M25.33 Other instability of joint (Forearm)	0.000	0.808	0.192
M24.06 Loose body in joint-Lower leg	0.000	0.814	0.186
M24.21 Disorder of ligament (Shoulder region)	0.001	0.814	0.185
M25.39 Other instability of joint (Site unspecified)	0.000	0.816	0.184
M25.38 Other instability of joint (Other)	0.000	0.816	0.184
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.816	0.184
M25.32 Other instability of joint (Upper arm)	0.000	0.816	0.184
M25.30 Other instability of joint (Multiple sites)	0.000	0.816	0.184
M25.5 Pain in joint	0.000	0.816	0.184
M25.71 Osteophyte (Shoulder region)	0.000	0.816	0.184
M24.09 Loose body in joint (Site unspecified)	0.001	0.819	0.180
M24.08 Loose body in joint (Other)	0.001	0.819	0.180
M24.04 Loose body in joint (Hand)	0.001	0.819	0.180
M24.00 Loose body in joint (Multiple sites)	0.001	0.819	0.180
M25.36 Other instability of joint (Lower leg)	0.000	0.820	0.180
M25.83 Other specified joint disorders (Forearm)	0.000	0.828	0.172
M15 Polyarthrosis	0.000	0.828	0.172
M65.39 Trigger finger-Site unspec	0.000	0.829	0.170
M65.38 Trigger finger-Other	0.000	0.829	0.170
M65.37 Trigger finger-Ankle/foot	0.000	0.829	0.170
M65.36 Trigger finger-Lower leg	0.000	0.829	0.170
M65.35 Trigger finger-Pelvic/thigh	0.000	0.829	0.170
M65.33 Trigger finger-Forearm	0.000	0.829	0.170
M65.32 Trigger finger-Upper arm	0.000	0.829	0.170
M65.31 Trigger finger-Shldr region	0.000	0.829	0.170
M65.30 Trigger finger-Mult sites	0.000	0.829	0.170
M25.37 Other instability of joint (Ankle and foot)	0.000	0.832	0.168
M25.79 Osteophyte (Site unspecified)	0.000	0.832	0.168
M24.07 Loose body in joint (Ankle and foot)	0.000	0.835	0.165
K44.1 Diaphragmatic hernia with gangrene	0.001	0.838	0.162
M24.05 Loose body in joint (Pelvic region and thigh)	0.001	0.841	0.159
M25.19 Fistula of joint (Site unspecified)	0.000	0.842	0.158
M25.18 Fistula of joint (Other)	0.000	0.842	0.158
M25.17 Fistula of joint (Ankle and foot)	0.000	0.842	0.158
M25.16 Fistula of joint (Lower leg)	0.000	0.842	0.158
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.842	0.158
M25.14 Fistula of joint (Hand)	0.000	0.842	0.158
M25.13 Fistula of joint (Forearm)	0.000	0.842	0.158
M25.12 Fistula of joint (Upper arm)	0.000	0.842	0.158
M25.11 Fistula of joint (Shoulder region)	0.000	0.842	0.158
M25.10 Fistula of joint (Multiple sites)	0.000	0.842	0.158
M25.29 Flail joint (Site unspecified)	0.000	0.842	0.158
M25.28 Flail joint (Other)	0.000	0.842	0.158
M25.27 Flail joint (Ankle and foot)	0.000	0.842	0.158
M25.26 Flail joint (Lower leg)	0.000	0.842	0.158
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.842	0.158
M25.24 Flail joint (Hand)	0.000	0.842	0.158
M25.23 Flail joint (Forearm)	0.000	0.842	0.158
M25.22 Flail joint (Upper arm)	0.000	0.842	0.158
M25.21 Flail joint (Shoulder region)	0.000	0.842	0.158
M25.20 Flail joint (Multiple sites)	0.000	0.842	0.158
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.842	0.158
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.842	0.158
M91-M94 Chondropathies	0.000	0.843	0.157
M66 Spontaneous rupture of synovium and tendon	0.000	0.845	0.155
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.846	0.154
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.000	0.849	0.151
M65.0 Abscess of tendon sheath	0.000	0.850	0.150
M67 Other disorders of synovium and tendon	0.000	0.852	0.148
M24.03 Loose body in joint (Forearm)	0.001	0.853	0.147
M25.09 Haemarthrosis (Site unspecified)	0.000	0.853	0.147
M25.08 Haemarthrosis (Other)	0.000	0.853	0.147
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.853	0.147
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.853	0.147
M25.04 Haemarthrosis (Hand)	0.000	0.853	0.147
M25.03 Haemarthrosis (Forearm)	0.000	0.853	0.147
M25.02 Haemarthrosis (Upper arm)	0.000	0.853	0.147
M25.01 Haemarthrosis (Shoulder region)	0.000	0.853	0.147
M25.00 Haemarthrosis (Multiple sites)	0.000	0.853	0.147
M86-M90 Other osteopathies	0.000	0.854	0.146
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.146	0.854	0.000
M65.2 Calcific tendinitis	0.000	0.855	0.145
M25.82 Other specified joint disorders (Upper arm)	0.000	0.857	0.143
I80 Phlebitis and thrombophlebitis	0.143	0.857	0.000
M65.1 Other infective (teno)synovitis	0.000	0.859	0.140
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.140	0.860	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.863	0.137
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.137	0.863	0.000
M25.31 Other instability of joint (Shoulder region)	0.000	0.863	0.137
M93 Other osteochondropathies	0.000	0.864	0.136
M35 Other systemic involvement of connective tissue	0.000	0.867	0.133
M25.53 Pain in joint (Forearm)	0.000	0.867	0.133
M15.1 Heberden's nodes (with arthropathy)	0.000	0.868	0.132
M24.01 Loose body in joint (Shoulder region)	0.001	0.869	0.131
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.131	0.869	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.000	0.869	0.131
M25.06 Haemarthrosis (Lower leg)	0.000	0.870	0.130
M31 Other necrotising vasculopathies	0.000	0.870	0.130
M60-M63 Disorders of muscles	0.000	0.870	0.130
M15.3 Secondary multiple arthrosis	0.000	0.871	0.129
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.871	0.129
M15.9 Polyarthrosis, unspecified	0.000	0.873	0.127
M65.8 Other synovitis and tenosynovitis	0.000	0.874	0.126
M25.86 Other specified joint disorders (Lower leg)	0.000	0.874	0.126
M15.8 Other polyarthrosis	0.000	0.876	0.124
M15.0 Primary generalised (osteo)arthrosis	0.000	0.876	0.123
M66.3 Spontaneous rupture of flexor tendons	0.000	0.877	0.123
M25.84 Other specified joint disorders (Hand)	0.000	0.878	0.122
M40-M43 Deforming dorsopathies	0.000	0.878	0.122
M24.02 Loose body in joint (Upper arm)	0.001	0.878	0.121
M25.54 Pain in joint (Hand)	0.000	0.880	0.120
M93.9 Osteochondropathy, unspecified	0.000	0.880	0.120
M94 Other disorders of cartilage	0.000	0.882	0.118
M25.4 Effusion of joint	0.000	0.882	0.118
M66.2 Spontaneous rupture of extensor tendons	0.000	0.883	0.117
M25.88 Other specified joint disorders (Other)	0.000	0.884	0.116
M66.4 Spontaneous rupture of other tendons	0.000	0.885	0.115
M25.9 Joint disorder, unspecified	0.000	0.885	0.115
M25.58 Pain in joint (Other)	0.000	0.888	0.112
M66.1 Rupture of synovium	0.000	0.889	0.111
M66.5 Spontaneous rupture of unspecified tendon	0.000	0.889	0.111
M00-M03 Infectious arthropathies	0.000	0.890	0.110
M90 Osteopathies in diseases classified elsewhere	0.000	0.890	0.109
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.000	0.891	0.109
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.000	0.891	0.109

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations