TreeWAS – Variant ID: rs2249694

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.137	0.863	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.118	0.882	0.000
O60-O75 Complications of labour and delivery	0.109	0.891	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.104	0.896	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.103	0.897	0.000
O72 Postpartum haemorrhage	0.096	0.904	0.000
O66 Other obstructed labour	0.095	0.905	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.094	0.906	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.093	0.907	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.093	0.907	0.000
O64.1 Obstructed labour due to breech presentation	0.091	0.909	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.090	0.910	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.089	0.911	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.089	0.911	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.087	0.913	0.000
O71 Other obstetric trauma	0.086	0.914	0.000
O70 Perineal laceration during delivery	0.086	0.914	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.084	0.916	0.000
O72.0 Third-stage haemorrhage	0.082	0.918	0.000
O70.2 Third degree perineal laceration during delivery	0.081	0.919	0.000
O74 Complications of anaesthesia during labour and delivery	0.081	0.919	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.081	0.919	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.081	0.919	0.000
O64.3 Obstructed labour due to brow presentation	0.079	0.921	0.000
O60 Preterm delivery	0.078	0.921	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.077	0.923	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.077	0.923	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.076	0.924	0.000
O64.5 Obstructed labour due to compound presentation	0.075	0.925	0.000
O64.4 Obstructed labour due to shoulder presentation	0.075	0.925	0.000
O66.2 Obstructed labour due to unusually large foetus	0.074	0.925	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.074	0.926	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.074	0.926	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.074	0.926	0.000
O69.3 Labour and delivery complicated by short cord	0.074	0.926	0.000
O64.2 Obstructed labour due to face presentation	0.074	0.926	0.000
O71.7 Obstetric haematoma of pelvis	0.071	0.929	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.071	0.929	0.000
O70.3 Fourth degree perineal laceration during delivery	0.071	0.929	0.000
O73 Retained placenta and membranes, without haemorrhage	0.070	0.930	0.000
O66.9 Obstructed labour, unspecified	0.069	0.931	0.000
O72.3 Postpartum coagulation defects	0.069	0.931	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.068	0.932	0.000
O66.1 Obstructed labour due to locked twins	0.068	0.932	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.068	0.932	0.000
O69.8 Labour and delivery complicated by other cord complications	0.068	0.932	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.068	0.932	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.067	0.933	0.000
O72.1 Other immediate postpartum haemorrhage	0.066	0.934	0.000
O61 Failed induction of labour	0.066	0.934	0.000
O71.4 Obstetric high vaginal laceration alone	0.064	0.935	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.064	0.936	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.064	0.936	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.064	0.936	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.064	0.936	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.064	0.936	0.000
O65.0 Obstructed labour due to deformed pelvis	0.064	0.936	0.000
O71.2 Postpartum inversion of uterus	0.062	0.938	0.000
O71.1 Rupture of uterus during labour	0.062	0.938	0.000
O71.0 Rupture of uterus before onset of labour	0.062	0.938	0.000
O70.9 Perineal laceration during delivery, unspecified	0.061	0.939	0.000
O71.3 Obstetric laceration of cervix	0.061	0.939	0.000
O66.4 Failed trial of labour, unspecified	0.061	0.939	0.000
O71.5 Other obstetric injury to pelvic organs	0.061	0.939	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.060	0.940	0.000
O66.8 Other specified obstructed labour	0.059	0.941	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.059	0.941	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.058	0.941	0.000
O71.9 Obstetric trauma, unspecified	0.058	0.942	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.058	0.942	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.058	0.942	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.058	0.942	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.058	0.942	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.058	0.942	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.058	0.942	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.058	0.942	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.058	0.942	0.000
O62 Abnormalities of forces of labour	0.058	0.942	0.000
O71.8 Other specified obstetric trauma	0.058	0.942	0.000
O60.3 Preterm delivery without spontaneous labour	0.056	0.943	0.000
O60.2 Preterm spontaneous labour with term delivery	0.056	0.943	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.056	0.943	0.000
O60.0 Preterm labour without delivery	0.056	0.943	0.000
O67.8 Other intrapartum haemorrhage	0.050	0.950	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.049	0.951	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.048	0.951	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.048	0.952	0.000
O61.1 Failed instrumental induction of labour	0.048	0.952	0.000
O61.8 Other failed induction of labour	0.047	0.952	0.000
O61.9 Failed induction of labour, unspecified	0.046	0.953	0.000
O73.0 Retained placenta, without haemorrhage	0.045	0.955	0.000
O62.1 Secondary uterine inertia	0.044	0.956	0.000
O63 Long labour	0.044	0.956	0.000
O62.8 Other abnormalities of forces of labour	0.042	0.958	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.042	0.958	0.000
O70.0 First degree perineal laceration during delivery	0.042	0.958	0.000
O62.9 Abnormality of forces of labour, unspecified	0.040	0.960	0.000
O62.3 Precipitate labour	0.040	0.960	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.039	0.961	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.035	0.964	0.000
O61.0 Failed medical induction of labour	0.035	0.965	0.000
O62.0 Primary inadequate contractions	0.035	0.965	0.000
O62.2 Other uterine inertia	0.034	0.966	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.032	0.968	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.029	0.971	0.000
O75.4 Other complications of obstetric surgery and procedures	0.028	0.972	0.000
O75.1 Shock during or following labour and delivery	0.028	0.972	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.028	0.972	0.000
O75.3 Other infection during labour	0.027	0.972	0.000
O75.9 Complication of labour and delivery, unspecified	0.027	0.972	0.000
O63.9 Long labour, unspecified	0.027	0.973	0.000
O63.1 Prolonged second stage (of labour)	0.027	0.973	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.026	0.973	0.000
O70.1 Second degree perineal laceration during delivery	0.026	0.974	0.000
O75.8 Other specified complications of labour and delivery	0.026	0.974	0.000
O75.0 Maternal distress during labour and delivery	0.022	0.977	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.979	0.021
I84.1 Internal haemorrhoids with other complications	0.021	0.979	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.981	0.019
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.981	0.019
O63.0 Prolonged first stage (of labour)	0.019	0.981	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.984	0.016
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.984	0.016
O42.9 Premature rupture of membranes, unspecified	0.015	0.985	0.000
K91.1 Postgastric surgery syndromes	0.000	0.985	0.015
K91.3 Postoperative intestinal obstruction	0.000	0.985	0.015
K22.1 Ulcer of oesophagus	0.013	0.987	0.000
O42 Premature rupture of membranes	0.013	0.987	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.987	0.013
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.012	0.988	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.011	0.988	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.011	0.989	0.000
K91.5 Postcholecystectomy syndrome	0.000	0.989	0.011
K11.2 Sialoadenitis	0.000	0.990	0.010
O42.2 Premature rupture of membranes, labour delayed by therapy	0.010	0.990	0.000
N94.6 Dysmenorrhoea, unspecified	0.009	0.991	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.008	0.992	0.000
K90-K93 Other diseases of the digestive system	0.000	0.993	0.007
O86 Other puerperal infections	0.007	0.993	0.000
O85-O92 Complications predominantly related to the puerperium	0.007	0.993	0.000
O86.4 Pyrexia of unknown origin following delivery	0.007	0.993	0.000
K11 Diseases of salivary glands	0.000	0.993	0.007
O14.9 Preeclampsia, unspecified	0.006	0.994	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.006	0.994	0.000
K92.8 Other specified diseases of digestive system	0.000	0.994	0.006
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.006	0.994	0.000
O85 Puerperal sepsis	0.006	0.994	0.000
O86.8 Other specified puerperal infections	0.006	0.994	0.000
O86.0 Infection of obstetric surgical wound	0.006	0.994	0.000
K92 Other diseases of digestive system	0.000	0.994	0.006
O20-O29 Other maternal disorders predominantly related to pregnancy	0.006	0.994	0.000
K11.9 Disease of salivary gland, unspecified	0.000	0.994	0.006
K92.9 Disease of digestive system, unspecified	0.000	0.994	0.006
O15 Eclampsia	0.006	0.994	0.000
O20 Haemorrhage in early pregnancy	0.006	0.994	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.006	0.994	0.000
O91 Infections of breast associated with childbirth	0.006	0.994	0.000
K11.8 Other diseases of salivary glands	0.000	0.994	0.006
O86.1 Other infection of genital tract following delivery	0.005	0.994	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.994	0.005
K11.3 Abscess of salivary gland	0.000	0.994	0.005
O86.3 Other genito-urinary tract infections following delivery	0.005	0.994	0.000
K11.7 Disturbances of salivary secretion	0.000	0.995	0.005
O88 Obstetric embolism	0.005	0.995	0.000
O28 Abnormal findings on antenatal screening of mother	0.005	0.995	0.000
O89 Complications of anaesthesia during the puerperium	0.005	0.995	0.000
K11.0 Atrophy of salivary gland	0.000	0.995	0.005
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O86.2 Urinary tract infection following delivery	0.005	0.995	0.000
K11.5 Sialolithiasis	0.000	0.995	0.005
O20.9 Haemorrhage in early pregnancy, unspecified	0.005	0.995	0.000
O20.8 Other haemorrhage in early pregnancy	0.005	0.995	0.000
O12.1 Gestational proteinuria	0.005	0.995	0.000
K11.4 Fistula of salivary gland	0.000	0.995	0.005
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.005	0.995	0.000
K92.0 Haematemesis	0.000	0.995	0.005
O14.2 HELLP syndrome	0.005	0.995	0.000
O12.0 Gestational oedema	0.005	0.995	0.000
O12.2 Gestational oedema with proteinuria	0.005	0.995	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.995	0.005
R04.0 Epistaxis	0.005	0.995	0.000
O24 Diabetes mellitus in pregnancy	0.005	0.995	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.005	0.995	0.000
N02.9 Unspecified	0.005	0.995	0.000
O30.0 Twin pregnancy	0.005	0.995	0.000
O30 Multiple gestation	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
O91.2 Nonpurulent mastitis associated with childbirth	0.004	0.995	0.000
O29 Complications of anaesthesia during pregnancy	0.004	0.995	0.000
O22 Venous complications in pregnancy	0.004	0.995	0.000
O25 Malnutrition in pregnancy	0.004	0.995	0.000
I42.9 Cardiomyopathy, unspecified	0.000	0.995	0.005
K31.7 Polyp of stomach and duodenum	0.005	0.995	0.000
K11.1 Hypertrophy of salivary gland	0.000	0.995	0.004
O15.9 Eclampsia, unspecified as to time period	0.004	0.996	0.000
O15.2 Eclampsia in the puerperium	0.004	0.996	0.000
O15.1 Eclampsia in labour	0.004	0.996	0.000
O15.0 Eclampsia in pregnancy	0.004	0.996	0.000
M07.30 Other psoriatic arthropathies (Multiple sites)	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.004	0.996	0.000
K22.4 Dyskinesia of oesophagus	0.004	0.996	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.004	0.996	0.000
O91.0 Infection of nipple associated with childbirth	0.004	0.996	0.000
O20.0 Threatened abortion	0.004	0.996	0.000
O91.1 Abscess of breast associated with childbirth	0.004	0.996	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.996	0.004
K93.1 Megacolon in Chagas' disease	0.000	0.996	0.004
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.996	0.004
K22 Other diseases of oesophagus	0.004	0.996	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.004	0.996	0.000
C67.2 Lateral wall of bladder	0.000	0.996	0.004
O88.8 Other obstetric embolism	0.004	0.996	0.000
O88.3 Obstetric pyaemic and septic embolism	0.004	0.996	0.000
O88.2 Obstetric blood-clot embolism	0.004	0.996	0.000
O88.1 Amniotic fluid embolism	0.004	0.996	0.000
O88.0 Obstetric air embolism	0.004	0.996	0.000
C67 Malignant neoplasm of bladder	0.000	0.996	0.004
O28.8 Other abnormal findings on antenatal screening of mother	0.004	0.996	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.004	0.996	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.004	0.996	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.004	0.996	0.000
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.004	0.996	0.000
O89.8 Other complications of anaesthesia during the puerperium	0.004	0.996	0.000
O89.6 Failed or difficult intubation during the puerperium	0.004	0.996	0.000
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.004	0.996	0.000
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.004	0.996	0.000
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.004	0.996	0.000
O89.1 Cardiac complications of anaesthesia during the puerperium	0.004	0.996	0.000
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.004	0.996	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.004	0.996	0.000
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.004	0.996	0.000
O87 Venous complications in the puerperium	0.004	0.996	0.000
K90 Intestinal malabsorption	0.000	0.996	0.004
O14.1 Severe preeclampsia	0.004	0.996	0.000
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.996	0.004
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O22.4 Haemorrhoids in pregnancy	0.004	0.996	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.004	0.996	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.004	0.996	0.000
C67.5 Bladder neck	0.000	0.996	0.004
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.996	0.004
O14.0 Moderate preeclampsia	0.004	0.996	0.000
C67.1 Dome of bladder	0.000	0.996	0.004
K22.7 Barrett's oesophagus	0.004	0.996	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.004	0.996	0.000
O16 Unspecified maternal hypertension	0.004	0.996	0.000
O41 Other disorders of amniotic fluid and membranes	0.004	0.996	0.000
C67.3 Anterior wall of bladder	0.000	0.996	0.004
O30.1 Triplet pregnancy	0.004	0.996	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.004	0.996	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.004	0.996	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.004	0.996	0.000
N94.0 Mittelschmerz	0.004	0.996	0.000
N64.5 Other signs and symptoms in breast	0.000	0.996	0.004
O94-O99 Other obstetric conditions, not elsewhere classified	0.004	0.996	0.000
C67.0 Trigone of bladder	0.000	0.996	0.004
O30.9 Multiple gestation, unspecified	0.003	0.996	0.000
O30.8 Other multiple gestation	0.003	0.996	0.000
O30.2 Quadruplet pregnancy	0.003	0.996	0.000
O21 Excessive vomiting in pregnancy	0.003	0.996	0.000
O40 Polyhydramnios	0.004	0.996	0.000
C67.4 Posterior wall of bladder	0.000	0.996	0.004
O90.5 Postpartum thyroiditis	0.003	0.996	0.000
O90.4 Postpartum acute renal failure	0.003	0.996	0.000
O90.3 Cardiomyopathy in the puerperium	0.003	0.996	0.000
C67.8 Overlapping lesion of bladder	0.000	0.996	0.004
N94.3 Premenstrual tension syndrome	0.004	0.996	0.000
O22.9 Venous complication in pregnancy, unspecified	0.003	0.996	0.000
O22.8 Other venous complications in pregnancy	0.003	0.996	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.003	0.996	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.003	0.996	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.003	0.996	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.003	0.996	0.000
O29.6 Failed or difficult intubation during pregnancy	0.003	0.996	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.003	0.996	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.003	0.996	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.003	0.996	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.003	0.996	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.003	0.996	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.003	0.996	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.996	0.000
K22.3 Perforation of oesophagus	0.003	0.996	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.003	0.996	0.000
O90.2 Haematoma of obstetric wound	0.003	0.996	0.000
O90.0 Disruption of Caesarean section wound	0.003	0.996	0.000
K90.9 Intestinal malabsorption, unspecified	0.000	0.996	0.003
K11.6 Mucocele of salivary gland	0.000	0.997	0.003
O33 Maternal care for known or suspected disproportion	0.003	0.997	0.000
O22.1 Genital varices in pregnancy	0.003	0.997	0.000
O90.1 Disruption of perineal obstetric wound	0.003	0.997	0.000
N94.1 Dyspareunia	0.003	0.997	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.003	0.997	0.000
O92.7 Other and unspecified disorders of lactation	0.003	0.997	0.000
O92.6 Galactorrhoea	0.003	0.997	0.000
O92.5 Suppressed lactation	0.003	0.997	0.000
O92.4 Hypogalactia	0.003	0.997	0.000
O92.3 Agalactia	0.003	0.997	0.000
O92.0 Retracted nipple associated with childbirth	0.003	0.997	0.000
K90.8 Other intestinal malabsorption	0.000	0.997	0.003
I31.3 Pericardial effusion (noninflammatory)	0.003	0.997	0.000
K22.5 Diverticulum of oesophagus, acquired	0.003	0.997	0.000
O31.8 Other complications specific to multiple gestation	0.003	0.997	0.000
O45 Premature separation of placenta [abruptio placentae]	0.003	0.997	0.000
Y60.0 During surgical operation	0.000	0.997	0.003
O90.8 Other complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
N94.2 Vaginismus	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.003	0.997	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.003	0.997	0.000
O90.9 Complication of the puerperium, unspecified	0.003	0.997	0.000
C67.7 Urachus	0.000	0.997	0.003
O26 Maternal care for other conditions predominantly related to pregnancy	0.003	0.997	0.000
O87.3 Cerebral venous thrombosis in the puerperium	0.003	0.997	0.000
O87.1 Deep phlebothrombosis in the puerperium	0.003	0.997	0.000
K90.3 Pancreatic steatorrhoea	0.000	0.997	0.003
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.997	0.003
K90.1 Tropical sprue	0.000	0.997	0.003
O87.2 Haemorrhoids in the puerperium	0.003	0.997	0.000
O41.1 Infection of amniotic sac and membranes	0.003	0.997	0.000
O87.9 Venous complication in the puerperium, unspecified	0.003	0.997	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.003	0.997	0.000
O21.0 Mild hyperemesis gravidarum	0.003	0.997	0.000
K22.0 Achalasia of cardia	0.003	0.997	0.000
N94.4 Primary dysmenorrhoea	0.003	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
O31.0 Papyraceous foetus	0.003	0.997	0.000
O44 Placenta praevia	0.003	0.997	0.000
C67.6 Ureteric orifice	0.000	0.997	0.003
O41.8 Other specified disorders of amniotic fluid and membranes	0.003	0.997	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.000	0.997	0.003
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.003	0.997	0.000
N94.5 Secondary dysmenorrhoea	0.003	0.997	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.997	0.003
O26.2 Pregnancy care of habitual aborter	0.003	0.997	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.997	0.001
O92.2 Other and unspecified disorders of breast associated with childbirth	0.003	0.997	0.000
I46.9 Cardiac arrest, unspecified	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.003	0.997	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.003	0.997	0.000
O95 Obstetric death of unspecified cause	0.003	0.997	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O87.8 Other venous complications in the puerperium	0.002	0.997	0.000
O36 Maternal care for other known or suspected foetal problems	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.000	0.997	0.003
O21.8 Other vomiting complicating pregnancy	0.003	0.997	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O26.5 Maternal hypotension syndrome	0.003	0.997	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.997	0.003
I42 Cardiomyopathy	0.000	0.997	0.003
O33.8 Maternal care for disproportion of other origin	0.003	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.003	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.003	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.003	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.003	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.003	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.003	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.003	0.997	0.000
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.002	0.997	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.997	0.003
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.003	0.997	0.000
O21.2 Late vomiting of pregnancy	0.002	0.997	0.000
O45.8 Other premature separation of placenta	0.002	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.002	0.997	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.002	0.997	0.001
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.003	0.997	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.003	0.997	0.000
O41.0 Oligohydramnios	0.003	0.997	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O26.4 Herpes gestationis	0.002	0.997	0.000
O26.1 Low weight gain in pregnancy	0.002	0.997	0.000
M07.3 Other psoriatic arthropathies	0.003	0.997	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.997	0.002
O26.0 Excessive weight gain in pregnancy	0.002	0.997	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.997	0.000
I31.9 Disease of pericardium, unspecified	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.997	0.003
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.002	0.997	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.002	0.997	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.002	0.997	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.002	0.997	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.002	0.997	0.000
O43 Placental disorders	0.002	0.997	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.997	0.002
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.003	0.997	0.000
K22.2 Oesophageal obstruction	0.003	0.997	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.997	0.002
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.002	0.997	0.000
I31 Other diseases of pericardium	0.002	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.002	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.002	0.998	0.000
O45.9 Premature separation of placenta, unspecified	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.000	0.998	0.002
O23.3 Infections of other parts of urinary tract in pregnancy	0.002	0.998	0.001
O23.2 Infections of urethra in pregnancy	0.002	0.998	0.001
O23.1 Infections of bladder in pregnancy	0.002	0.998	0.001
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.002	0.998	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.002	0.998	0.000
O33.9 Maternal care for disproportion, unspecified	0.002	0.998	0.000
O96.9 Death from unspecified obstetric cause	0.002	0.998	0.000
O96.1 Death from indirect obstetric cause	0.002	0.998	0.000
O96.0 Death from direct obstetric cause	0.002	0.998	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.002	0.998	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.002	0.998	0.000
O97.0 Death from sequelae of direct obstetric cause	0.002	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.000	0.998	0.002
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.998	0.002
O36.2 Maternal care for hydrops foetalis	0.002	0.998	0.000
N02 Recurrent and persistent haematuria	0.002	0.998	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.002
O21.9 Vomiting of pregnancy, unspecified	0.002	0.998	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
N63 Unspecified lump in breast	0.000	0.998	0.002
O23.0 Infections of kidney in pregnancy	0.002	0.998	0.001
K62.0 Anal polyp	0.000	0.998	0.002
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
I31.1 Chronic constrictive pericarditis	0.002	0.998	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.000	0.998	0.002
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.002
C67.9 Bladder, unspecified	0.000	0.998	0.002
W10.8 Other specified place	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
N62 Hypertrophy of breast	0.000	0.998	0.002
I31.0 Chronic adhesive pericarditis	0.002	0.998	0.000
I42.4 Endocardial fibroelastosis	0.000	0.998	0.002
O26.9 Pregnancy-related condition, unspecified	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
N02.8 Other	0.002	0.998	0.000
O36.1 Maternal care for other isoimmunisation	0.002	0.998	0.000
O43.2 Morbidly adherent placenta	0.002	0.998	0.000
I34.1 Mitral (valve) prolapse	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.002	0.998	0.000
O43.0 Placental transfusion syndromes	0.002	0.998	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
K22.9 Disease of oesophagus, unspecified	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
I31.8 Other specified diseases of pericardium	0.002	0.998	0.000
I31.2 Haemopericardium, not elsewhere classified	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.001
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
M25.8 Other specified joint disorders	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.000	0.998	0.002
N02.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
O43.9 Placental disorder, unspecified	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.002	0.998	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.998	0.002
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.998	0.002
O36.9 Maternal care for foetal problem, unspecified	0.002	0.998	0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle	0.002	0.998	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O82 Single delivery by Caesarean section	0.000	0.998	0.002
I21 Acute myocardial infarction	0.000	0.998	0.002
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
N02.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
N02.6 Dense deposit disease	0.002	0.998	0.000
N02.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.998	0.000
N02.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N02.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
F43.1 Posttraumatic stress disorder	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.001	0.998	0.001
O34.1 Maternal care for tumour of corpus uteri	0.002	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
M25.88 Other specified joint disorders (Other)	0.002	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
H10 Conjunctivitis	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations