TreeWAS – Variant ID: rs225848

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.043	0.957	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.021	0.979	0.000
M23.2 Derangement of meniscus due to old tear or injury	0.019	0.981	0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.017	0.983	0.000
M23.3 Other meniscus derangements	0.017	0.983	0.000
M23 Internal derangement of knee	0.016	0.984	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.014	0.986	0.000
M23.9 Internal derangement of knee, unspecified	0.013	0.987	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.013	0.987	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.013	0.987	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.013	0.987	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.013	0.987	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.013	0.987	0.000
M23.37 Other meniscus derangements-Capsular lig	0.012	0.987	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.012	0.988	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.012	0.988	0.000
M23.5 Chronic instability of knee	0.012	0.988	0.000
M23.1 Discoid meniscus (congenital)	0.012	0.988	0.000
M23.8 Other internal derangements of knee	0.012	0.988	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.012	0.988	0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.012	0.988	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.012	0.988	0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.011	0.989	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.011	0.989	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.010	0.990	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.010	0.990	0.000
E83.5 Disorders of calcium metabolism	0.010	0.990	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.010	0.990	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
M23.0 Cystic meniscus	0.010	0.990	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.010	0.990	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.010	0.990	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.010	0.990	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.010	0.990	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.010	0.990	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.010	0.990	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.010	0.990	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.010	0.990	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.009	0.991	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.009	0.991	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.009	0.991	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.009	0.991	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.009	0.991	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.009	0.991	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.009	0.991	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.009	0.991	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.009	0.991	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.009	0.991	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.009	0.991	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.009	0.991	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.009	0.991	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.009	0.991	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.009	0.991	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.009	0.991	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.009	0.991	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.009	0.991	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.009	0.991	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.009	0.991	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.009	0.991	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.009	0.991	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.009	0.991	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.009	0.991	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.009	0.991	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.009	0.991	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.008	0.992	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.008	0.992	0.000
M31 Other necrotising vasculopathies	0.008	0.992	0.000
M20-M25 Other joint disorders	0.008	0.992	0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified	0.008	0.992	0.000
M24 Other specific joint derangements	0.008	0.992	0.000
M23.4 Loose body in knee	0.005	0.992	0.003
M24.1 Other articular cartilage disorders	0.008	0.992	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.007	0.992	0.000
M34 Systemic sclerosis	0.007	0.992	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.007	0.992	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.007	0.993	0.000
M31.3 Wegener's granulomatosis	0.007	0.993	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.007	0.993	0.000
M23.07 Cystic meniscus-Capsular lig	0.007	0.993	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.007	0.993	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.007	0.993	0.000
M23.00 Cystic meniscus (Multiple sites)	0.007	0.993	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.007	0.993	0.000
M31.6 Other giant cell arteritis	0.007	0.993	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.007	0.993	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.007	0.993	0.000
M24.5 Contracture of joint	0.007	0.993	0.000
M22 Disorders of patella	0.007	0.993	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.007	0.993	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.006	0.993	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.993	0.007
M31.0 Hypersensitivity angiitis	0.007	0.993	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.007	0.993	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.006	0.994	0.000
M31.1 Thrombotic microangiopathy	0.006	0.994	0.000
M33 Dermatopolymyositis	0.006	0.994	0.000
M34.9 Systemic sclerosis, unspecified	0.006	0.994	0.000
M31.7 Microscopic polyangiitis	0.006	0.994	0.000
M34.1 CR(E)ST syndrome	0.006	0.994	0.000
M31.9 Necrotising vasculopathy, unspecified	0.006	0.994	0.000
M22.4 Chondromalacia patellae	0.006	0.994	0.000
M23.49 Loose body in knee-Unspec lig/men	0.001	0.994	0.005
M31.2 Lethal midline granuloma	0.006	0.994	0.000
M24.51 Contracture of joint (Shoulder region)	0.006	0.994	0.000
M34.8 Other forms of systemic sclerosis	0.006	0.994	0.000
M31.8 Other specified necrotising vasculopathies	0.006	0.994	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.006	0.994	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.006	0.994	0.000
M24.14 Other articular cartilage disorders (Hand)	0.006	0.994	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.006	0.994	0.000
M23.47 Loose body in knee-Capsular lig	0.004	0.994	0.002
M23.45 Loose body in knee-Pst hrn lat men	0.004	0.994	0.002
M22.8 Other disorders of patella	0.006	0.994	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.004	0.994	0.002
M30 Polyarteritis nodosa and related conditions	0.006	0.994	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.003	0.994	0.002
M23.41 Loose body in knee-Ant lig/hrn men	0.003	0.994	0.002
M24.6 Ankylosis of joint	0.006	0.994	0.000
M23.46 Loose body in knee-O/unsp lat men	0.003	0.994	0.002
M24.19 Other articular cartilage disorders (Site unspecified)	0.006	0.994	0.000
M24.18 Other articular cartilage disorders (Other)	0.006	0.994	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.006	0.994	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.006	0.994	0.000
M23.43 Loose body in knee-Med lig/oth men	0.003	0.994	0.002
M23.40 Loose body in knee-Mult sites	0.003	0.994	0.003
M24.0 Loose body in joint	0.006	0.994	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.006	0.994	0.000
M24.7 Protrusio acetabuli	0.006	0.994	0.000
M24.2 Disorder of ligament	0.006	0.994	0.000
M32 Systemic lupus erythematosus	0.006	0.994	0.000
M24.54 Contracture of joint (Hand)	0.006	0.994	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.006	0.994	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.005	0.994	0.000
M24.9 Joint derangement, unspecified	0.005	0.994	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.005	0.994	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.005	0.994	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.005	0.994	0.000
M21 Other acquired deformities of limbs	0.005	0.994	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.005	0.994	0.000
M79.8 Other specified soft tissue disorders	0.000	0.994	0.006
M24.55 Contracture of joint (Pelvic region and thigh)	0.005	0.994	0.000
M34.0 Progressive systemic sclerosis	0.005	0.994	0.000
M24.56 Contracture of joint (Lower leg)	0.005	0.995	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.005	0.995	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.000	0.995	0.005
M24.4 Recurrent dislocation and subluxation of joint	0.005	0.995	0.000
M24.59 Contracture of joint (Site unspecified)	0.005	0.995	0.000
M24.58 Contracture of joint (Other)	0.005	0.995	0.000
M24.53 Contracture of joint (Forearm)	0.005	0.995	0.000
M24.50 Contracture of joint (Multiple sites)	0.005	0.995	0.000
M22.1 Recurrent subluxation of patella	0.005	0.995	0.000
M22.3 Other derangements of patella	0.005	0.995	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.005	0.995	0.000
M24.57 Contracture of joint (Ankle and foot)	0.005	0.995	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.005	0.995	0.000
M33.2 Polymyositis	0.005	0.995	0.000
M33.1 Other dermatomyositis	0.005	0.995	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.005	0.995	0.000
M22.2 Patellofemoral disorders	0.005	0.995	0.000
M22.0 Recurrent dislocation of patella	0.005	0.995	0.000
M33.0 Juvenile dermatomyositis	0.005	0.995	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M33.9 Dermatopolymyositis, unspecified	0.005	0.995	0.000
M24.28 Disorder of ligament (Other)	0.005	0.995	0.000
M22.9 Disorder of patella, unspecified	0.005	0.995	0.000
M30.0 Polyarteritis nodosa	0.005	0.995	0.000
M24.52 Contracture of joint (Upper arm)	0.005	0.995	0.000
M24.01 Loose body in joint (Shoulder region)	0.005	0.995	0.000
M24.64 Ankylosis of joint (Hand)	0.005	0.995	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M21.0 Valgus deformity, not elsewhere classified	0.005	0.995	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.005	0.995	0.000
M24.06 Loose body in joint-Lower leg	0.004	0.995	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.004	0.995	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.004	0.995	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.004	0.995	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.004	0.995	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.004	0.995	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.004	0.995	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.004	0.995	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.004	0.995	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.004	0.995	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.004	0.995	0.000
M21.6 Other acquired deformities of ankle and foot	0.004	0.995	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.004	0.995	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.995	0.004
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.004	0.995	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.004	0.995	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.004	0.995	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.004	0.995	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.004	0.995	0.000
M30.2 Juvenile polyarteritis	0.004	0.995	0.000
M24.04 Loose body in joint (Hand)	0.004	0.995	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.000	0.995	0.004
M24.69 Ankylosis of joint (Site unspecified)	0.004	0.996	0.000
M24.68 Ankylosis of joint (Other)	0.004	0.996	0.000
M24.63 Ankylosis of joint (Forearm)	0.004	0.996	0.000
M24.62 Ankylosis of joint (Upper arm)	0.004	0.996	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.004	0.996	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.004	0.996	0.000
M21.4 Flat foot [pes planus] (acquired)	0.004	0.996	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.996	0.004
M24.09 Loose body in joint (Site unspecified)	0.004	0.996	0.000
M24.08 Loose body in joint (Other)	0.004	0.996	0.000
M24.00 Loose body in joint (Multiple sites)	0.004	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.004	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.004	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.004	0.996	0.000
M24.79 Protrusio acetabuli-Site unspec	0.004	0.996	0.000
M24.78 Protrusio acetabuli-Other	0.004	0.996	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.004	0.996	0.000
M24.76 Protrusio acetabuli-Lower leg	0.004	0.996	0.000
M24.74 Protrusio acetabuli-Hand	0.004	0.996	0.000
M24.73 Protrusio acetabuli-Forearm	0.004	0.996	0.000
M24.72 Protrusio acetabuli-Upper arm	0.004	0.996	0.000
M24.71 Protrusio acetabuli-Shldr region	0.004	0.996	0.000
M24.70 Protrusio acetabuli-Mult sites	0.004	0.996	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.004	0.996	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.004	0.996	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.004	0.996	0.000
M36.3 Arthropathy in other blood disorders	0.004	0.996	0.000
M36.2 Haemophilic arthropathy	0.004	0.996	0.000
M36.1 Arthropathy in neoplastic disease	0.004	0.996	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.004	0.996	0.000
L08 Other local infections of skin and subcutaneous tissue	0.004	0.996	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.004	0.996	0.000
M24.66 Ankylosis of joint (Lower leg)	0.004	0.996	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.004	0.996	0.000
M24.98 Joint derangement, unspecified (Other)	0.004	0.996	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.004	0.996	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.004	0.996	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.004	0.996	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.004	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.004	0.996	0.000
M24.03 Loose body in joint (Forearm)	0.004	0.996	0.000
M79.88 Other specified soft tissue disorders (Other)	0.000	0.996	0.004
M24.94 Joint derangement, unspecified (Hand)	0.004	0.996	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.004	0.996	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.996	0.004
M32.1 Systemic lupus erythematosus with organ or system involvement	0.004	0.996	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.02 Loose body in joint (Upper arm)	0.004	0.996	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.996	0.004
N94.1 Dyspareunia	0.000	0.996	0.004
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.996	0.004
M24.67 Ankylosis of joint (Ankle and foot)	0.004	0.996	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.004	0.996	0.000
M24.23 Disorder of ligament (Forearm)	0.004	0.996	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.004	0.996	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.004	0.996	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.004	0.996	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.004	0.996	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.004	0.996	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.004	0.996	0.000
M21.3 Wrist or foot drop (acquired)	0.004	0.996	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.004	0.996	0.000
M24.26 Disorder of ligament (Lower leg)	0.004	0.996	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.004	0.996	0.000
M32.8 Other forms of systemic lupus erythematosus	0.004	0.996	0.000
M21.7 Unequal limb length (acquired)	0.004	0.996	0.000
M21.8 Other specified acquired deformities of limbs	0.004	0.996	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.004	0.996	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.004	0.996	0.000
G58.9 Mononeuropathy, unspecified	0.000	0.996	0.004
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.996	0.004
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.003	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
M21.2 Flexion deformity	0.004	0.996	0.000
M21.9 Acquired deformity of limb, unspecified	0.004	0.996	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.004	0.996	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.004	0.996	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.003	0.996	0.000
M21.1 Varus deformity, not elsewhere classified	0.003	0.996	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.003	0.996	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.003	0.996	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.003	0.996	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.003	0.996	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.003	0.996	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.003	0.996	0.000
H18 Other disorders of cornea	0.004	0.996	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.004	0.996	0.000
M35 Other systemic involvement of connective tissue	0.004	0.996	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.003	0.996	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.996	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.996	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.996	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.996	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.996	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.996	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.003	0.996	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.003	0.996	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.003	0.996	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.003	0.996	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.003	0.996	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.003	0.996	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.003	0.996	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.003	0.996	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.003	0.996	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.003	0.996	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.003	0.996	0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.003	0.997	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.003	0.997	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.003	0.997	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.003	0.997	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.003	0.997	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.003	0.997	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.003	0.997	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.003	0.997	0.000
G58.8 Other specified mononeuropathies	0.000	0.997	0.003
H35.8 Other specified retinal disorders	0.003	0.997	0.000
L08.1 Erythrasma	0.003	0.997	0.000
H18.6 Keratoconus	0.003	0.997	0.000
H20 Iridocyclitis	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
G58 Other mononeuropathies	0.000	0.997	0.003
L08.0 Pyoderma	0.003	0.997	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.003	0.997	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.003	0.997	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.003	0.997	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.003	0.997	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.003	0.997	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.003	0.997	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.003	0.997	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.003	0.997	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.003	0.997	0.000
H18.9 Disorder of cornea, unspecified	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.003	0.997	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.003	0.997	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.003	0.997	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.003	0.997	0.000
M21.78 Unequal limb length (acquired)-Other	0.003	0.997	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.003	0.997	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.003	0.997	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.003	0.997	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.003	0.997	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.003	0.997	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.003	0.997	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.003	0.997	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.003	0.997	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.003	0.997	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.003	0.997	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.003	0.997	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.003	0.997	0.000
H18.4 Corneal degeneration	0.003	0.997	0.000
H18.3 Changes in corneal membranes	0.003	0.997	0.000
H20.8 Other iridocyclitis	0.003	0.997	0.000
H18.5 Hereditary corneal dystrophies	0.003	0.997	0.000
M21.24 Flexion deformity (Hand)	0.003	0.997	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.003	0.997	0.000
M35.1 Other overlap syndromes	0.003	0.997	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.003	0.997	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.003	0.997	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M21.29 Flexion deformity (Site unspecified)	0.003	0.997	0.000
M21.28 Flexion deformity (Other)	0.003	0.997	0.000
M21.22 Flexion deformity (Upper arm)	0.003	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
H18.7 Other corneal deformities	0.003	0.997	0.000
M35.7 Hypermobility syndrome	0.003	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.003	0.997	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.003	0.997	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.003	0.997	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.003	0.997	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.003	0.997	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.003	0.997	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.003	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.003	0.997	0.000
G58.7 Mononeuritis multiplex	0.000	0.997	0.003
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.003	0.997	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.003	0.997	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.003	0.997	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
H18.0 Corneal pigmentations and deposits	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.003	0.997	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.003	0.997	0.000
H18.2 Other corneal oedema	0.003	0.997	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.997	0.003
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.003	0.997	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.003	0.997	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.003	0.997	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.003	0.997	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.003	0.997	0.000
M35.5 Multifocal fibrosclerosis	0.003	0.997	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.002	0.997	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.997	0.003
M35.4 Diffuse (eosinophilic) fasciitis	0.003	0.997	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.002	0.997	0.000
H18.1 Bullous keratopathy	0.003	0.997	0.000
H20.1 Chronic iridocyclitis	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
M20.4 Other hammer toe(s) (acquired)	0.003	0.997	0.000
M35.8 Other specified systemic involvement of connective tissue	0.003	0.997	0.000
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
M35.2 Behcet's disease	0.002	0.997	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.997	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.997	0.000
G58.0 Intercostal neuropathy	0.000	0.997	0.002
M20 Acquired deformities of fingers and toes	0.003	0.997	0.000
H15 Disorders of sclera	0.002	0.997	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.003	0.997	0.000
R06.0 Dyspnoea	0.000	0.997	0.003
T84.1 Mechanical complication of internal fixation device of bones of limb	0.000	0.997	0.003
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.002	0.997	0.000
R20.2 Paraesthesia of skin	0.002	0.998	0.000
R06.5 Mouth breathing	0.000	0.998	0.002
W25.9 Unspecified place	0.000	0.998	0.002
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
H33.0 Retinal detachment with retinal break	0.002	0.998	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.998	0.002
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.002	0.998	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
Z93.2 Ileostomy status	0.000	0.998	0.002
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
O14.9 Preeclampsia, unspecified	0.002	0.998	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.002	0.998	0.000
H21.4 Pupillary membranes	0.002	0.998	0.000
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
H16.0 Corneal ulcer	0.002	0.998	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.002	0.998	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
L53.9 Erythematous condition, unspecified	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.002	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
H17 Corneal scars and opacities	0.002	0.998	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
H21.0 Hyphaema	0.002	0.998	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.000	0.998	0.002
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.998	0.002
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
N94.3 Premenstrual tension syndrome	0.000	0.998	0.002
L57 Skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
O04.9 Complete or unspecified, without complication	0.002	0.998	0.000
O63.1 Prolonged second stage (of labour)	0.002	0.998	0.000
H35 Other retinal disorders	0.002	0.998	0.000
W25 Contact with sharp glass	0.000	0.998	0.002
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
H35.0 Background retinopathy and retinal vascular changes	0.002	0.998	0.000
H16.4 Corneal neovascularisation	0.002	0.998	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
C90.0 Multiple myeloma	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.002	0.998	0.000
O12.0 Gestational oedema	0.002	0.998	0.000
T79.8 Other early complications of trauma	0.000	0.998	0.002
H16.9 Keratitis, unspecified	0.002	0.998	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.002	0.998	0.000
O12.1 Gestational proteinuria	0.002	0.998	0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.998	0.002
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.998	0.002
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.002	0.998	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
O12.2 Gestational oedema with proteinuria	0.002	0.998	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
H35.6 Retinal haemorrhage	0.002	0.998	0.000
I86.1 Scrotal varices	0.000	0.998	0.002
O14.2 HELLP syndrome	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations