TreeWAS – Variant ID: rs2273

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R45.1 Restlessness and agitation	0.000	0.966	0.034
R45.8 Other symptoms and signs involving emotional state	0.000	0.967	0.033
R45 Symptoms and signs involving emotional state	0.000	0.968	0.032
R45.2 Unhappiness	0.000	0.973	0.027
R45.4 Irritability and anger	0.000	0.973	0.027
R45.6 Physical violence	0.000	0.976	0.024
R45.7 State of emotional shock and stress, unspecified	0.000	0.976	0.024
R45.3 Demoralisation and apathy	0.000	0.977	0.023
R45.5 Hostility	0.000	0.978	0.022
R45.0 Nervousness	0.000	0.979	0.021
H81.0 Meniere's disease	0.018	0.982	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.000	0.983	0.017
Z59 Problems related to housing and economic circumstances	0.000	0.984	0.016
M79.65 Pain in limb (Pelvic region and thigh)	0.016	0.984	0.000
N50.1 Vascular disorders of male genital organs	0.016	0.984	0.000
Z59.0 Homelessness	0.000	0.984	0.015
S72.00 Fracture of neck of femur (closed)	0.015	0.985	0.000
Z57 Occupational exposure to risk-factors	0.000	0.985	0.015
Z63 Other problems related to primary support group, including family circumstances	0.000	0.985	0.015
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.985	0.015
Z56 Problems related to employment and unemployment	0.000	0.985	0.015
Z58 Problems related to physical environment	0.000	0.986	0.014
Z59.8 Other problems relating to housing and economic circumstances	0.000	0.986	0.014
Z64 Problems related to certain psychosocial circumstances	0.000	0.986	0.014
Z61 Problems related to negative life events in childhood	0.000	0.986	0.014
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.986	0.014
Z56.0 Unemployment, unspecified	0.000	0.986	0.014
Z65 Problems related to other psychosocial circumstances	0.000	0.986	0.014
Z99.8 Dependence on other enabling machines and devices	0.000	0.986	0.014
Z63.7 Other stressful life events affecting family and household	0.000	0.987	0.013
Z63.5 Disruption of family by separation and divorce	0.000	0.987	0.013
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.000	0.987	0.012
Z57.2 Occupational exposure to dust	0.000	0.988	0.012
Z62 Other problems related to upbringing	0.000	0.988	0.012
Z55 Problems related to education and literacy	0.000	0.988	0.012
Z58.1 Exposure to air pollution	0.000	0.988	0.012
Z64.0 Problems related to unwanted pregnancy	0.000	0.988	0.012
Z59.7 Insufficient social insurance and welfare support	0.000	0.988	0.012
Z59.6 Low income	0.000	0.988	0.012
Z59.5 Extreme poverty	0.000	0.988	0.012
Z59.4 Lack of adequate food	0.000	0.988	0.012
Z59.3 Problems related to living in residential institution	0.000	0.988	0.012
Z59.2 Discord with neighbours, lodgers and landlord	0.000	0.988	0.012
Z63.6 Dependent relative needing care at home	0.000	0.988	0.012
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.000	0.989	0.011
Z65.8 Other specified problems related to psychosocial circumstances	0.000	0.989	0.011
Z58.5 Exposure to other pollution	0.000	0.989	0.011
Z63.8 Other specified problems related to primary support group	0.000	0.989	0.011
Z58.7 Exposure to tobacco smoke	0.000	0.989	0.011
K08.3 Retained dental root	0.000	0.989	0.011
Z57.9 Occupational exposure to unspecified risk-factor	0.000	0.989	0.011
Z57.7 Occupational exposure to vibration	0.000	0.989	0.011
Z57.6 Occupational exposure to extreme temperature	0.000	0.989	0.011
Z57.4 Occupational exposure to toxic agents in agriculture	0.000	0.989	0.011
Z57.1 Occupational exposure to radiation	0.000	0.989	0.011
Z57.0 Occupational exposure to noise	0.000	0.989	0.011
Z63.9 Problem related to primary support group, unspecified	0.000	0.989	0.011
Z63.3 Absence of family member	0.000	0.989	0.011
Z63.2 Inadequate family support	0.000	0.989	0.011
Z63.1 Problems in relationship with parents and in-laws	0.000	0.989	0.011
Z56.6 Other physical and mental strain related to work	0.000	0.989	0.011
Z59.1 Inadequate housing	0.000	0.989	0.011
Z56.7 Other and unspecified problems related to employment	0.000	0.989	0.011
Z56.5 Uncongenial work	0.000	0.989	0.011
Z56.4 Discord with boss and workmates	0.000	0.989	0.011
Z56.2 Threat of job loss	0.000	0.989	0.011
Z56.1 Change of job	0.000	0.989	0.011
Z58.9 Problem related to physical environment, unspecified	0.000	0.989	0.010
Z58.6 Inadequate drinking-water supply	0.000	0.989	0.010
Z58.4 Exposure to radiation	0.000	0.989	0.010
Z58.3 Exposure to soil pollution	0.000	0.989	0.010
Z58.2 Exposure to water pollution	0.000	0.989	0.010
Z58.0 Exposure to noise	0.000	0.989	0.010
Z56.3 Stressful work schedule	0.000	0.989	0.010
Z57.8 Occupational exposure to other risk-factors	0.000	0.989	0.010
S62.60 Fracture of other finger (closed)	0.010	0.990	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.000	0.990	0.010
Z64.4 Discord with counsellors	0.000	0.990	0.010
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.000	0.990	0.010
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.000	0.990	0.010
Z64.1 Problems related to multiparity	0.000	0.990	0.010
Z61.6 Problems related to alleged physical abuse of child	0.000	0.990	0.010
Z61.9 Negative life events in childhood, unspecified	0.000	0.990	0.010
Z61.8 Other negative life events in childhood	0.000	0.990	0.010
Z61.7 Personal frightening experience in childhood	0.000	0.990	0.010
Z61.3 Events resulting in loss of self-esteem in childhood	0.000	0.990	0.010
Z61.2 Altered pattern of family relationships in childhood	0.000	0.990	0.010
Z61.1 Removal from home in childhood	0.000	0.990	0.010
Z61.0 Loss of love relationship in childhood	0.000	0.990	0.010
Z65.9 Problem related to unspecified psychosocial circumstances	0.000	0.990	0.010
Z65.5 Exposure to disaster, war and other hostilities	0.000	0.990	0.010
Z65.4 Victim of crime and terrorism	0.000	0.990	0.010
Z65.3 Problems related to other legal circumstances	0.000	0.990	0.010
Z65.2 Problems related to release from prison	0.000	0.990	0.010
Z65.1 Imprisonment and other incarceration	0.000	0.990	0.010
Z65.0 Conviction in civil and criminal proceedings without imprisonment	0.000	0.990	0.010
Z58.8 Other problems related to physical environment	0.000	0.990	0.010
Z57.3 Occupational exposure to other air contaminants	0.000	0.990	0.010
Z63.0 Problems in relationship with spouse or partner	0.000	0.990	0.010
S72.0 Fracture of neck of femur	0.010	0.990	0.000
Z60 Problems related to social environment	0.000	0.990	0.010
Z55.9 Problems relating to education and literacy, unspecified	0.000	0.991	0.009
Z55.8 Other problems relating to education and literacy	0.000	0.991	0.009
Z55.4 Educational maladjustment and discord with teachers and classmates	0.000	0.991	0.009
Z55.3 Underachievement in school	0.000	0.991	0.009
Z55.2 Failed examinations	0.000	0.991	0.009
Z55.1 Schooling unavailable and unattainable	0.000	0.991	0.009
Z55.0 Illiteracy and low-level literacy	0.000	0.991	0.009
Z62.9 Problem related to upbringing, unspecified	0.000	0.991	0.009
Z62.8 Other specified problems related to upbringing	0.000	0.991	0.009
Z62.6 Inappropriate parental pressure and other abnormal qualities of upbringing	0.000	0.991	0.009
Z62.5 Other problems related to neglect in upbringing	0.000	0.991	0.009
Z62.4 Emotional neglect of child	0.000	0.991	0.009
Z62.3 Hostility towards and scapegoating of child	0.000	0.991	0.009
Z62.2 Institutional upbringing	0.000	0.991	0.009
Z62.1 Parental overprotection	0.000	0.991	0.009
Z62.0 Inadequate parental supervision and control	0.000	0.991	0.009
H81 Disorders of vestibular function	0.009	0.991	0.000
Z63.4 Disappearance and death of family member	0.000	0.991	0.009
N48.8 Other specified disorders of penis	0.009	0.991	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.992	0.008
H61.0 Perichondritis of external ear	0.000	0.992	0.008
S32.0 Fracture of lumbar vertebra	0.000	0.992	0.008
H81.9 Disorder of vestibular function, unspecified	0.008	0.992	0.000
Z60.8 Other problems related to social environment	0.000	0.992	0.008
Z60.9 Problem related to social environment, unspecified	0.000	0.992	0.008
H81.8 Other disorders of vestibular function	0.008	0.992	0.000
S72.01 Fracture of neck of femur (open)	0.007	0.993	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.000	0.993	0.007
Z60.4 Social exclusion and rejection	0.000	0.993	0.007
Z60.3 Acculturation difficulty	0.000	0.993	0.007
Z60.1 Atypical parenting situation	0.000	0.993	0.007
Z60.0 Problems of adjustment to life-cycle transitions	0.000	0.993	0.007
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.993	0.007
H81.4 Vertigo of central origin	0.007	0.993	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.993	0.006
S32.01 Fracture of lumbar vertebra (open)	0.000	0.994	0.006
K08 Other disorders of teeth and supporting structures	0.000	0.994	0.006
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.994	0.006
H81.3 Other peripheral vertigo	0.006	0.994	0.000
H80-H83 Diseases of inner ear	0.006	0.994	0.000
E16.1 Other hypoglycaemia	0.000	0.994	0.006
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.994	0.005
S72 Fracture of femur	0.006	0.994	0.000
N50 Other disorders of male genital organs	0.006	0.994	0.000
H80 Otosclerosis	0.005	0.995	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.995	0.005
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.995	0.005
S72.2 Subtrochanteric fracture	0.005	0.995	0.000
S72.20 Subtrochanteric fracture (closed)	0.005	0.995	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.995	0.005
G81.9 Hemiplegia, unspecified	0.000	0.995	0.005
S72.3 Fracture of shaft of femur	0.005	0.995	0.000
S72.30 Fracture of shaft of femur (closed)	0.005	0.995	0.000
H80.9 Otosclerosis, unspecified	0.005	0.995	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.995	0.005
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.995	0.005
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.995	0.005
E16.4 Abnormal secretion of gastrin	0.000	0.995	0.005
E16.3 Increased secretion of glucagon	0.000	0.995	0.005
T91.3 Sequelae of injury of spinal cord	0.000	0.995	0.005
N50.9 Disorder of male genital organs, unspecified	0.005	0.995	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.000	0.995	0.005
H80.0 Otosclerosis involving oval window, nonobliterative	0.005	0.995	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.000	0.995	0.005
D86 Sarcoidosis	0.000	0.995	0.005
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.995	0.005
D89.3 Immune reconstitution syndrome	0.000	0.995	0.004
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.000	0.995	0.005
D86.8 Sarcoidosis of other and combined sites	0.000	0.995	0.005
D89.1 Cryoglobulinaemia	0.000	0.995	0.004
D86.0 Sarcoidosis of lung	0.000	0.995	0.004
D80-D89 Certain disorders involving the immune mechanism	0.000	0.996	0.004
H81.2 Vestibular neuronitis	0.004	0.996	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.004	0.996	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.996	0.004
S72.7 Multiple fractures of femur	0.004	0.996	0.000
H80.8 Other otosclerosis	0.004	0.996	0.000
H80.2 Cochlear otosclerosis	0.004	0.996	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.004	0.996	0.000
H83 Other diseases of inner ear	0.004	0.996	0.000
M79.61 Pain in limb (Shoulder region)	0.004	0.996	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.996	0.004
S62.6 Fracture of other finger	0.004	0.996	0.000
M79.60 Pain in limb (Multiple sites)	0.004	0.996	0.000
S72.21 Subtrochanteric fracture (open)	0.004	0.996	0.000
H18.5 Hereditary corneal dystrophies	0.004	0.996	0.000
S72.4 Fracture of lower end of femur	0.004	0.996	0.000
G80.9 Infantile cerebral palsy, unspecified	0.004	0.996	0.000
S72.8 Fractures of other parts of femur	0.004	0.996	0.000
D12.8 Rectum	0.004	0.996	0.000
S72.31 Fracture of shaft of femur (open)	0.004	0.996	0.000
M79.6 Pain in limb	0.004	0.996	0.000
G81 Hemiplegia	0.000	0.996	0.004
H18.2 Other corneal oedema	0.004	0.996	0.000
G81.1 Spastic hemiplegia	0.000	0.996	0.004
S72.9 Fracture of femur, part unspecified	0.003	0.996	0.000
D84 Other immunodeficiencies	0.000	0.996	0.004
H83.8 Other specified diseases of inner ear	0.004	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.996	0.004
H83.9 Disease of inner ear, unspecified	0.004	0.996	0.000
Z92.8 Personal history of other medical treatment	0.004	0.996	0.000
H61 Other disorders of external ear	0.000	0.996	0.004
H18 Other disorders of cornea	0.003	0.996	0.000
D81 Combined immunodeficiencies	0.000	0.997	0.003
S06.00 Concussion (without open intracranial wound)	0.000	0.997	0.003
H83.3 Noise effects on inner ear	0.003	0.997	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.997	0.003
S72.71 Multiple fractures of femur (open)	0.003	0.997	0.000
S72.70 Multiple fractures of femur (closed)	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
H18.8 Other specified disorders of cornea	0.003	0.997	0.000
N71.1 Chronic inflammatory disease of uterus	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.997	0.003
H83.2 Labyrinthine dysfunction	0.003	0.997	0.000
H83.1 Labyrinthine fistula	0.003	0.997	0.000
N50.8 Other specified disorders of male genital organs	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.997	0.003
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.000	0.997	0.003
N50.0 Atrophy of testis	0.003	0.997	0.000
S72.40 Fracture of lower end of femur (closed)	0.003	0.997	0.000
S72.81 Fractures of other parts of femur (open)	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.000	0.997	0.003
S32.4 Fracture of acetabulum	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.000	0.997	0.003
J98.8 Other specified respiratory disorders	0.003	0.997	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.997	0.003
H18.1 Bullous keratopathy	0.003	0.997	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.997	0.003
G81.0 Flaccid hemiplegia	0.000	0.997	0.003
D84.8 Other specified immunodeficiencies	0.000	0.997	0.003
D84.9 Immunodeficiency, unspecified	0.000	0.997	0.003
E29.1 Testicular hypofunction	0.000	0.997	0.003
M79.62 Pain in limb (Upper arm)	0.003	0.997	0.000
D84.1 Defects in the complement system	0.000	0.997	0.003
D86.3 Sarcoidosis of skin	0.000	0.997	0.003
H18.3 Changes in corneal membranes	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.997	0.003
H72.0 Central perforation of tympanic membrane	0.000	0.997	0.003
S72.41 Fracture of lower end of femur (open)	0.003	0.997	0.000
S72.91 Fracture of femur, part unspecified (open)	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.997	0.003
S72.80 Fractures of other parts of femur (closed)	0.003	0.997	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.997	0.003
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.997	0.003
H18.7 Other corneal deformities	0.003	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.997	0.003
H18.0 Corneal pigmentations and deposits	0.003	0.997	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.003	0.997	0.000
M79.67 Pain in limb (Ankle and foot)	0.003	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.997	0.003
M79.69 Pain in limb (Site unspecified)	0.003	0.997	0.000
S72.1 Pertrochanteric fracture	0.003	0.997	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.997	0.003
D81.9 Combined immunodeficiency, unspecified	0.000	0.997	0.003
D81.8 Other combined immunodeficiencies	0.000	0.997	0.003
D81.7 Major histocompatibility complex class II deficiency	0.000	0.997	0.003
D81.6 Major histocompatibility complex class I deficiency	0.000	0.997	0.003
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.997	0.003
D81.4 Nezelof's syndrome	0.000	0.997	0.003
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.997	0.003
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.997	0.003
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.997	0.003
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.997	0.003
T91.1 Sequelae of fracture of spine	0.000	0.997	0.003
L03.9 Cellulitis, unspecified	0.000	0.997	0.003
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.997	0.003
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.997	0.003
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.997	0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.997	0.003
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.997	0.003
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.997	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.997	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.997	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.997	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.997	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.997	0.002
S32.2 Fracture of coccyx	0.000	0.997	0.002
D23.5 Skin of trunk	0.000	0.997	0.003
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.997	0.003
S62.61 Fracture of other finger (open)	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.997	0.002
H61.3 Acquired stenosis of external ear canal	0.000	0.997	0.003
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
G80 Infantile cerebral palsy	0.002	0.997	0.001
H81.1 Benign paroxysmal vertigo	0.002	0.997	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.997	0.002
F33 Recurrent depressive disorder	0.000	0.997	0.003
S32.41 Fracture of acetabulum (open)	0.000	0.997	0.002
D83.8 Other common variable immunodeficiencies	0.000	0.997	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.997	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.997	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.997	0.002
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.997	0.003
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.997	0.003
Z36.8 Other antenatal screening	0.000	0.997	0.003
D82.1 Di George's syndrome	0.000	0.997	0.002
I21.2 Acute transmural myocardial infarction of other sites	0.003	0.997	0.000
T78.3 Angioneurotic oedema	0.002	0.997	0.000
C16.0 Cardia	0.000	0.998	0.002
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.998	0.002
I95.2 Hypotension due to drugs	0.002	0.998	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.998	0.002
E06.3 Autoimmune thyroiditis	0.000	0.998	0.002
H15.1 Episcleritis	0.002	0.998	0.000
M79.64 Pain in limb (Hand)	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.002	0.998	0.000
M79.68 Pain in limb (Other)	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
I86.1 Scrotal varices	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.998	0.002
G80.8 Other infantile cerebral palsy	0.002	0.998	0.000
S72.11 Pertrochanteric fracture (open)	0.002	0.998	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.998	0.002
C16.1 Fundus of stomach	0.000	0.998	0.002
H15 Disorders of sclera	0.002	0.998	0.000
H16 Keratitis	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.998	0.002
H60-H62 Diseases of external ear	0.000	0.998	0.002
S32.3 Fracture of ilium	0.000	0.998	0.002
C16.3 Pyloric antrum	0.000	0.998	0.002
G80.2 Infantile hemiplegia	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.000	0.998	0.002
C16 Malignant neoplasm of stomach	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.000	0.998	0.002
S32.20 Fracture of coccyx (closed)	0.000	0.998	0.002
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
H60 Otitis externa	0.000	0.998	0.002
T68 Hypothermia	0.002	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.998	0.002
M95.0 Acquired deformity of nose	0.000	0.998	0.002
G80.4 Ataxic cerebral palsy	0.002	0.998	0.001
G80.3 Dyskinetic cerebral palsy	0.002	0.998	0.001
Q28 Other congenital malformations of circulatory system	0.000	0.998	0.002
C16.2 Body of stomach	0.000	0.998	0.002
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.002
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
H60.1 Cellulitis of external ear	0.000	0.998	0.002
G80.1 Spastic diplegia	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
T91 Sequelae of injuries of neck and trunk	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.000	0.998	0.002
Y76.2 Prosthetic and other implants, materials and accessory devices	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.000	0.998	0.002
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.998	0.002
H16.0 Corneal ulcer	0.002	0.998	0.000
K50.9 Crohn's disease, unspecified	0.002	0.998	0.000
H60.5 Acute otitis externa, non-infective	0.000	0.998	0.002
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
H16.8 Other keratitis	0.002	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.000	0.998	0.002
T66 Unspecified effects of radiation	0.002	0.998	0.000
Z99.4 Dependence on artificial heart	0.000	0.998	0.002
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.998	0.002
G80.0 Spastic cerebral palsy	0.001	0.998	0.001
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.998	0.002
Z36.1 Antenatal screening for raised alphafetoprotein level	0.000	0.998	0.002
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.998	0.002
H16.4 Corneal neovascularisation	0.002	0.998	0.000
H60.0 Abscess of external ear	0.000	0.998	0.002
Z36 Antenatal screening	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.000	0.998	0.002
M79.63 Pain in limb (Forearm)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
H61.8 Other specified disorders of external ear	0.000	0.998	0.002
S32.5 Fracture of pubis	0.000	0.998	0.002
H20 Iridocyclitis	0.002	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.000	0.998	0.002
S32.31 Fracture of ilium (open)	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
C16.4 Pylorus	0.000	0.998	0.002
S32.11 Fracture of sacrum (open)	0.000	0.998	0.002
R70.0 Elevated erythrocyte sedimentation rate	0.000	0.998	0.002
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
S51.0 Open wound of elbow	0.000	0.998	0.002
Z99.0 Dependence on aspirator	0.000	0.998	0.002
D23.7 Skin of lower limb, including hip	0.002	0.998	0.000
H20.9 Iridocyclitis, unspecified	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.998	0.002
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.998	0.002
Q28.1 Other malformations of precerebral vessels	0.000	0.998	0.002
T23.3 Burn of third degree of wrist and hand	0.000	0.998	0.002
C16.8 Overlapping lesion of stomach	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.000	0.998	0.002
H16.9 Keratitis, unspecified	0.002	0.998	0.000
H60.3 Other infective otitis externa	0.000	0.998	0.002
H60.2 Malignant otitis externa	0.000	0.998	0.002
S06.0 Concussion	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.998	0.002
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.998	0.002
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.998	0.002
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
K00.6 Disturbances in tooth eruption	0.000	0.998	0.002
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.000	0.998	0.002
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
G83.4 Cauda equina syndrome	0.000	0.998	0.002
T66-T78 Other and unspecified effects of external causes	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.002	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
J98.4 Other disorders of lung	0.002	0.998	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.000	0.998	0.002
H20.8 Other iridocyclitis	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.002
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
K81.9 Cholecystitis, unspecified	0.000	0.998	0.002
Z36.5 Antenatal screening for isoimmunisation	0.000	0.998	0.002
L84 Corns and callosities	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
S92.0 Fracture of calcaneus	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.998	0.002
H20.2 Lens-induced iridocyclitis	0.001	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
M95.2 Other acquired deformity of head	0.000	0.998	0.002
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.001
H62.8 Other disorders of external ear in diseases classified elsewhere	0.000	0.998	0.001
H62.4 Otitis externa in other diseases classified elsewhere	0.000	0.998	0.001
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
H62.2 Otitis externa in mycoses	0.000	0.998	0.001
H62.1 Otitis externa in viral diseases classified elsewhere	0.000	0.998	0.001
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.000	0.998	0.001
K56.5 Intestinal adhesions [bands] with obstruction	0.002	0.998	0.000
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
T70 Effects of air pressure and water pressure	0.002	0.998	0.000
O70.9 Perineal laceration during delivery, unspecified	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.000	0.998	0.002
H61.2 Impacted cerumen	0.000	0.998	0.002
J98.6 Disorders of diaphragm	0.002	0.998	0.000
H17 Corneal scars and opacities	0.001	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.001
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.001	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
H60.8 Other otitis externa	0.000	0.998	0.001
K00.9 Disorder of tooth development, unspecified	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.001
T23 Burn and corrosion of wrist and hand	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.998	0.001
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.998	0.002
S05.8 Other injuries of eye and orbit	0.000	0.998	0.001
T70.3 Caisson disease [decompression sickness]	0.001	0.998	0.000
T75 Effects of other external causes	0.001	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.001	0.998	0.000
T75.4 Effects of electric current	0.001	0.998	0.000
T74 Maltreatment syndromes	0.001	0.998	0.000
T73 Effects of other deprivation	0.001	0.998	0.000
T69 Other effects of reduced temperature	0.001	0.998	0.000
T67 Effects of heat and light	0.001	0.998	0.000
S92.01 Fracture of calcaneus (open)	0.001	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
H18.4 Corneal degeneration	0.001	0.998	0.001
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.001	0.998	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.998	0.001
T78 Adverse effects, not elsewhere classified	0.001	0.998	0.000
Y76 Obstetric and gynaecological devices associated with adverse incidents	0.001	0.998	0.000
C02.1 Border of tongue	0.000	0.999	0.001
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.999	0.001
T71 Asphyxiation	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
C71.9 Brain, unspecified	0.001	0.999	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.001	0.999	0.000
Q87.4 Marfan's syndrome	0.000	0.999	0.001
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.000	0.999	0.001
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.999	0.001
C66 Malignant neoplasm of ureter	0.001	0.999	0.000
G83 Other paralytic syndromes	0.000	0.999	0.001
G82.3 Flaccid tetraplegia	0.000	0.999	0.001
G82.0 Flaccid paraplegia	0.000	0.999	0.001
H17.8 Other corneal scars and opacities	0.001	0.999	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.999	0.001
S92.4 Fracture of great toe	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations