TreeWAS – Variant ID: rs227731

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D80.1 Nonfamilial hypogammaglobulinaemia	0.043	0.957	0.000
D80 Immunodeficiency with predominantly antibody defects	0.043	0.957	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.039	0.961	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.035	0.965	0.000
D80-D89 Certain disorders involving the immune mechanism	0.034	0.966	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.034	0.966	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.034	0.966	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.033	0.967	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.032	0.968	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.031	0.969	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.031	0.969	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.031	0.969	0.000
A04.8 Other specified bacterial intestinal infections	0.029	0.971	0.000
D62 Acute posthaemorrhagic anaemia	0.029	0.971	0.000
D84 Other immunodeficiencies	0.027	0.973	0.000
D61.9 Aplastic anaemia, unspecified	0.027	0.973	0.000
D86 Sarcoidosis	0.027	0.973	0.000
D60-D64 Aplastic and other anaemias	0.026	0.974	0.000
D61 Other aplastic anaemias	0.026	0.974	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.026	0.974	0.000
D82 Immunodeficiency associated with other major defects	0.025	0.975	0.000
D83 Common variable immunodeficiency	0.025	0.975	0.000
D81 Combined immunodeficiencies	0.025	0.975	0.000
D86.0 Sarcoidosis of lung	0.024	0.976	0.000
D86.3 Sarcoidosis of skin	0.024	0.976	0.000
D86.1 Sarcoidosis of lymph nodes	0.022	0.978	0.000
D84.1 Defects in the complement system	0.022	0.978	0.000
D84.8 Other specified immunodeficiencies	0.022	0.978	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.022	0.978	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.021	0.979	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.020	0.980	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.020	0.980	0.000
J33.8 Other polyp of sinus	0.000	0.981	0.019
D63 Anaemia in chronic diseases classified elsewhere	0.019	0.981	0.000
D61.8 Other specified aplastic anaemias	0.019	0.981	0.000
D61.3 Idiopathic aplastic anaemia	0.019	0.981	0.000
D61.2 Aplastic anaemia due to other external agents	0.019	0.981	0.000
D89.3 Immune reconstitution syndrome	0.019	0.981	0.000
D82.1 Di George's syndrome	0.019	0.981	0.000
D61.0 Constitutional aplastic anaemia	0.019	0.981	0.000
D89.1 Cryoglobulinaemia	0.019	0.981	0.000
D84.9 Immunodeficiency, unspecified	0.019	0.981	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.019	0.981	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.018	0.982	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.018	0.982	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.018	0.982	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.018	0.982	0.000
D82.2 Immunodeficiency with short-limbed stature	0.018	0.982	0.000
D82.0 Wiskott-Aldrich syndrome	0.018	0.982	0.000
D61.1 Drug-induced aplastic anaemia	0.018	0.982	0.000
D81.9 Combined immunodeficiency, unspecified	0.018	0.982	0.000
D81.8 Other combined immunodeficiencies	0.018	0.982	0.000
D81.7 Major histocompatibility complex class II deficiency	0.018	0.982	0.000
D81.6 Major histocompatibility complex class I deficiency	0.018	0.982	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.018	0.982	0.000
D81.4 Nezelof's syndrome	0.018	0.982	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.018	0.982	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.018	0.982	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.018	0.982	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.018	0.982	0.000
D83.8 Other common variable immunodeficiencies	0.018	0.982	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.018	0.982	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.018	0.982	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.018	0.982	0.000
D83.9 Common variable immunodeficiency, unspecified	0.018	0.982	0.000
D50.8 Other iron deficiency anaemias	0.017	0.983	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.017	0.983	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.017	0.983	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.015	0.985	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.015	0.985	0.000
D50-D53 Nutritional anaemias	0.014	0.986	0.000
D63.1 Anaemia in other chronic diseases classified elsewhere	0.014	0.986	0.000
D86.8 Sarcoidosis of other and combined sites	0.014	0.986	0.000
D60.8 Other acquired pure red cell aplasias	0.013	0.986	0.000
D60.1 Transient acquired pure red cell aplasia	0.013	0.986	0.000
D60.0 Chronic acquired pure red cell aplasia	0.013	0.986	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.013	0.987	0.000
D50 Iron deficiency anaemia	0.013	0.987	0.000
D63.0 Anaemia in neoplastic disease	0.013	0.987	0.000
D55-D59 Haemolytic anaemias	0.010	0.989	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.011	0.989	0.000
D64 Other anaemias	0.010	0.990	0.000
D50.1 Sideropenic dysphagia	0.010	0.990	0.000
D53 Other nutritional anaemias	0.010	0.990	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.009	0.991	0.000
D52 Folate deficiency anaemia	0.009	0.991	0.000
D57 Sickle-cell disorders	0.008	0.992	0.000
D55 Anaemia due to enzyme disorders	0.008	0.992	0.000
D59 Acquired haemolytic anaemia	0.008	0.992	0.000
D64.4 Congenital dyserythropoietic anaemia	0.008	0.992	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.008	0.992	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.008	0.992	0.000
D64.0 Hereditary sideroblastic anaemia	0.008	0.992	0.000
D64.3 Other sideroblastic anaemias	0.007	0.993	0.000
M88.9 Paget's disease of bone, unspecified	0.007	0.993	0.000
D53.8 Other specified nutritional anaemias	0.007	0.993	0.000
D53.2 Scorbutic anaemia	0.007	0.993	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.007	0.993	0.000
D53.0 Protein deficiency anaemia	0.007	0.993	0.000
D64.8 Other specified anaemias	0.007	0.993	0.000
D51 Vitamin B12 deficiency anaemia	0.007	0.993	0.000
D52.8 Other folate deficiency anaemias	0.007	0.993	0.000
D52.1 Drug-induced folate deficiency anaemia	0.007	0.993	0.000
D52.0 Dietary folate deficiency anaemia	0.007	0.993	0.000
D53.9 Nutritional anaemia, unspecified	0.006	0.993	0.000
D57.1 Sickle-cell anaemia without crisis	0.006	0.994	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.006	0.994	0.000
D58 Other hereditary haemolytic anaemias	0.006	0.994	0.000
D57.8 Other sickle-cell disorders	0.006	0.994	0.000
D57.3 Sickle-cell trait	0.006	0.994	0.000
D57.2 Double heterozygous sickling disorders	0.006	0.994	0.000
D57.0 Sickle-cell anaemia with crisis	0.006	0.994	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.006	0.994	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.006	0.994	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.006	0.994	0.000
D55.8 Other anaemias due to enzyme disorders	0.006	0.994	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.006	0.994	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.006	0.994	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.006	0.994	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.006	0.994	0.000
D56 Thalassaemia	0.006	0.994	0.000
F17.2 Dependence syndrome	0.000	0.994	0.006
D59.8 Other acquired haemolytic anaemias	0.006	0.994	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.006	0.994	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.006	0.994	0.000
D59.3 Haemolytic-uraemic syndrome	0.006	0.994	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.006	0.994	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.006	0.994	0.000
M88 Paget's disease of bone [osteitis deformans]	0.006	0.994	0.000
D52.9 Folate deficiency anaemia, unspecified	0.006	0.994	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.005	0.994	0.000
F81 Specific developmental disorders of scholastic skills	0.006	0.994	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.005	0.994	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.005	0.994	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.005	0.994	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.005	0.994	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.005	0.994	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.005	0.994	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.005	0.994	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
D86.9 Sarcoidosis, unspecified	0.005	0.995	0.000
D51.2 Transcobalamin II deficiency	0.005	0.995	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.005	0.995	0.000
Z04.3 Examination and observation following other accident	0.005	0.995	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.005	0.995	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.005	0.995	0.000
D58.2 Other haemoglobinopathies	0.005	0.995	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.005	0.995	0.000
D59.1 Other autoimmune haemolytic anaemias	0.005	0.995	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.005	0.995	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.004	0.995	0.000
D58.1 Hereditary elliptocytosis	0.004	0.995	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.005	0.995	0.000
C44.2 Skin of ear and external auricular canal	0.000	0.995	0.005
M86.6 Other chronic osteomyelitis	0.005	0.995	0.000
K75.4 Autoimmune hepatitis	0.000	0.995	0.005
D56.9 Thalassaemia, unspecified	0.004	0.995	0.000
D56.8 Other thalassaemias	0.004	0.995	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.004	0.995	0.000
D56.2 Delta-beta thalassaemia	0.004	0.995	0.000
D56.0 Alpha thalassaemia	0.004	0.995	0.000
M88.0 Paget's disease of skull	0.004	0.996	0.000
M88.8 Paget's disease of other bones	0.004	0.996	0.000
F81.8 Other developmental disorders of scholastic skills	0.004	0.996	0.000
F81.3 Mixed disorder of scholastic skills	0.004	0.996	0.000
F81.2 Specific disorder of arithmetical skills	0.004	0.996	0.000
F81.1 Specific spelling disorder	0.004	0.996	0.000
F81.0 Specific reading disorder	0.004	0.996	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.004	0.996	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.004	0.996	0.000
D66 Hereditary factor VIII deficiency	0.004	0.996	0.000
M86-M90 Other osteopathies	0.004	0.996	0.000
D58.0 Hereditary spherocytosis	0.004	0.996	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.004	0.996	0.000
M86 Osteomyelitis	0.004	0.996	0.000
A04 Other bacterial intestinal infections	0.004	0.996	0.000
D56.3 Thalassaemia trait	0.003	0.996	0.001
J33 Nasal polyp	0.000	0.996	0.004
F10.2 Dependence syndrome	0.000	0.996	0.004
D58.9 Hereditary haemolytic anaemia, unspecified	0.003	0.996	0.000
D67 Hereditary factor IX deficiency	0.004	0.996	0.000
M88.00 Paget's disease of skull-Mult sites	0.003	0.996	0.000
N30.0 Acute cystitis	0.004	0.996	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.003	0.996	0.000
M86.68 Other chronic osteomyelitis (Other)	0.003	0.996	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.003	0.996	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.003	0.996	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.003	0.996	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.003	0.996	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.003	0.996	0.000
D56.1 Beta thalassaemia	0.003	0.996	0.001
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.996	0.000
M88.09 Paget's disease of skull-Site unspec	0.003	0.997	0.000
M88.08 Paget's disease of skull-Other	0.003	0.997	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.003	0.997	0.000
M88.06 Paget's disease of skull-Lower Leg	0.003	0.997	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.003	0.997	0.000
M88.04 Paget's disease of skull-Hand	0.003	0.997	0.000
M88.03 Paget's disease of skull-Forearm	0.003	0.997	0.000
M88.02 Paget's disease of skull-Upper arm	0.003	0.997	0.000
M88.01 Paget's disease of skull-Shldr region	0.003	0.997	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.003	0.997	0.000
M88.88 Paget's disease of other bones (Other)	0.003	0.997	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.003	0.997	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.003	0.997	0.000
M88.84 Paget's disease of other bones (Hand)	0.003	0.997	0.000
M88.83 Paget's disease of other bones (Forearm)	0.003	0.997	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.003	0.997	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.003	0.997	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.003	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.997	0.003
A48.1 Legionnaires' disease	0.003	0.997	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.003	0.997	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.997	0.003
J33.1 Polypoid sinus degeneration	0.000	0.997	0.003
M87 Osteonecrosis	0.003	0.997	0.000
A04.4 Other intestinal Escherichia coli infections	0.003	0.997	0.000
A04.9 Bacterial intestinal infection, unspecified	0.003	0.997	0.000
M90 Osteopathies in diseases classified elsewhere	0.003	0.997	0.000
C16.9 Stomach, unspecified	0.003	0.997	0.000
A04.6 Enteritis due to Yersinia enterocolitica	0.003	0.997	0.000
A04.3 Enterohaemorrhagic Escherichia coli infection	0.003	0.997	0.000
A04.2 Enteroinvasive Escherichia coli infection	0.003	0.997	0.000
A04.1 Enterotoxigenic Escherichia coli infection	0.003	0.997	0.000
A04.0 Enteropathogenic Escherichia coli infection	0.003	0.997	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.003	0.997	0.000
M86.3 Chronic multifocal osteomyelitis	0.003	0.997	0.000
M86.2 Subacute osteomyelitis	0.003	0.997	0.000
M86.0 Acute haematogenous osteomyelitis	0.003	0.997	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.003	0.997	0.000
M86.8 Other osteomyelitis	0.003	0.997	0.000
C16.0 Cardia	0.003	0.997	0.000
G81.9 Hemiplegia, unspecified	0.000	0.997	0.003
Z03.1 Observation for suspected malignant neoplasm	0.003	0.997	0.000
M86.1 Other acute osteomyelitis	0.003	0.997	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.997	0.003
M87.1 Osteonecrosis due to drugs	0.003	0.997	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.003	0.997	0.000
C16 Malignant neoplasm of stomach	0.003	0.997	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.003	0.997	0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.003	0.997	0.000
A48.8 Other specified bacterial diseases	0.003	0.997	0.000
C16.3 Pyloric antrum	0.003	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.997	0.003
R49.0 Dysphonia	0.003	0.997	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.003	0.997	0.000
M87.8 Other osteonecrosis	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.003	0.997	0.000
M87.2 Osteonecrosis due to previous trauma	0.003	0.997	0.000
M87.3 Other secondary osteonecrosis	0.003	0.997	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.003	0.997	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.003
X23.9 Unspecified place	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.003	0.997	0.000
M90.6 Osteitis deformans in neoplastic disease	0.002	0.997	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.002	0.997	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.002	0.997	0.000
M90.3 Osteonecrosis in caisson disease	0.002	0.997	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.002	0.997	0.000
M90.0 Tuberculosis of bone	0.002	0.997	0.000
A48 Other bacterial diseases, not elsewhere classified	0.003	0.997	0.000
M86.86 Other osteomyelitis (Lower leg)	0.002	0.997	0.000
M90.84 Osteopathy in other diseases classified elsewhere (Hand)	0.002	0.997	0.000
N36.0 Urethral fistula	0.003	0.997	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
C16.4 Pylorus	0.002	0.997	0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.002	0.997	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.002	0.997	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.002	0.997	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.002	0.997	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.28 Subacute osteomyelitis (Other)	0.002	0.997	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.24 Subacute osteomyelitis (Hand)	0.002	0.997	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.002	0.997	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.002	0.997	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.002	0.997	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.002	0.997	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.002	0.997	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.002	0.997	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.002	0.997	0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.002	0.997	0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.002	0.997	0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.002	0.997	0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.002	0.997	0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.002	0.997	0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.002	0.997	0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.002	0.997	0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.002	0.997	0.000
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.002	0.997	0.000
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.002	0.997	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.002	0.997	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.002	0.998	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.002	0.998	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.002	0.998	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.002	0.998	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.002	0.998	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.002	0.998	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.002	0.998	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.002	0.998	0.000
C16.1 Fundus of stomach	0.002	0.998	0.000
M87.9 Osteonecrosis, unspecified	0.002	0.998	0.000
N80.8 Other endometriosis	0.000	0.998	0.002
M86.89 Other osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.88 Other osteomyelitis (Other)	0.002	0.998	0.000
M86.84 Other osteomyelitis (Hand)	0.002	0.998	0.000
M86.83 Other osteomyelitis (Forearm)	0.002	0.998	0.000
M86.82 Other osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.81 Other osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.80 Other osteomyelitis (Multiple sites)	0.002	0.998	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.000	0.998	0.002
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.002	0.998	0.000
M86.18 Other acute osteomyelitis (Other)	0.002	0.998	0.000
M86.16 Other acute osteomyelitis (Lower leg)	0.002	0.998	0.000
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M86.14 Other acute osteomyelitis (Hand)	0.002	0.998	0.000
M86.13 Other acute osteomyelitis (Forearm)	0.002	0.998	0.000
M86.12 Other acute osteomyelitis (Upper arm)	0.002	0.998	0.000
M86.11 Other acute osteomyelitis (Shoulder region)	0.002	0.998	0.000
M86.10 Other acute osteomyelitis (Multiple sites)	0.002	0.998	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.002	0.998	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.002	0.998	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.002	0.998	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.002	0.998	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.002	0.998	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.002	0.998	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.002	0.998	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.002	0.998	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.002	0.998	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.002	0.998	0.000
M90.19 Periostitis in other infectious diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M90.18 Periostitis in other infectious diseases classified elsewhere (Other)	0.002	0.998	0.000
M90.17 Periostitis in other infectious diseases classified elsewhere (Ankle and foot)	0.002	0.998	0.000
M90.16 Periostitis in other infectious diseases classified elsewhere (Lower leg)	0.002	0.998	0.000
M90.15 Periostitis in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.002	0.998	0.000
M90.14 Periostitis in other infectious diseases classified elsewhere (Hand)	0.002	0.998	0.000
M90.13 Periostitis in other infectious diseases classified elsewhere (Forearm)	0.002	0.998	0.000
M90.12 Periostitis in other infectious diseases classified elsewhere (Upper arm)	0.002	0.998	0.000
M90.11 Periostitis in other infectious diseases classified elsewhere (Shoulder region)	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.000	0.998	0.002
K21.0 Gastro-oesophageal reflux disease with oesophagitis	0.002	0.998	0.000
C16.8 Overlapping lesion of stomach	0.002	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.998	0.002
J31.0 Chronic rhinitis	0.002	0.998	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
M90.89 Osteopathy in other diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M90.88 Osteopathy in other diseases classified elsewhere (Other)	0.002	0.998	0.000
M90.87 Osteopathy in other diseases classified elsewhere (Ankle and foot)	0.002	0.998	0.000
M90.86 Osteopathy in other diseases classified elsewhere (Lower leg)	0.002	0.998	0.000
M90.85 Osteopathy in other diseases classified elsewhere (Pelvic region and thigh)	0.002	0.998	0.000
M90.83 Osteopathy in other diseases classified elsewhere (Forearm)	0.002	0.998	0.000
M90.82 Osteopathy in other diseases classified elsewhere (Upper arm)	0.002	0.998	0.000
M90.81 Osteopathy in other diseases classified elsewhere (Shoulder region)	0.002	0.998	0.000
M90.80 Osteopathy in other diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.002	0.998	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.88 Other osteonecrosis (Other)	0.002	0.998	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.86 Other osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.84 Other osteonecrosis (Hand)	0.002	0.998	0.000
M87.83 Other osteonecrosis (Forearm)	0.002	0.998	0.000
M87.82 Other osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.002	0.998	0.000
S06.0 Concussion	0.000	0.998	0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.002	0.998	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.002	0.998	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.002	0.998	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.002	0.998	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.002	0.998	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.002	0.998	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.002	0.998	0.000
C16.2 Body of stomach	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
F20.0 Paranoid schizophrenia	0.002	0.998	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.002	0.998	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.002	0.998	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.002	0.998	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.002	0.998	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.002	0.998	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.002	0.998	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.002	0.998	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.002	0.998	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.002	0.998	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.002	0.998	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.002	0.998	0.000
M87.38 Other secondary osteonecrosis (Other)	0.002	0.998	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.002	0.998	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.002	0.998	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.002	0.998	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.002	0.998	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.002	0.998	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.002	0.998	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.002	0.998	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
M90.09 Tuberculosis of bone (Site unspecified)	0.002	0.998	0.000
M90.08 Tuberculosis of bone (Other)	0.002	0.998	0.000
M90.07 Tuberculosis of bone (Ankle and foot)	0.002	0.998	0.000
M90.06 Tuberculosis of bone (Lower leg)	0.002	0.998	0.000
M90.05 Tuberculosis of bone (Pelvic region and thigh)	0.002	0.998	0.000
M90.04 Tuberculosis of bone (Hand)	0.002	0.998	0.000
M90.03 Tuberculosis of bone (Forearm)	0.002	0.998	0.000
M90.02 Tuberculosis of bone (Upper arm)	0.002	0.998	0.000
M90.01 Tuberculosis of bone (Shoulder region)	0.002	0.998	0.000
M90.00 Tuberculosis of bone (Multiple sites)	0.002	0.998	0.000
M90.29 Osteopathy in other infectious diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M90.28 Osteopathy in other infectious diseases classified elsewhere (Other)	0.002	0.998	0.000
M90.27 Osteopathy in other infectious diseases classified elsewhere (Ankle and foot)	0.002	0.998	0.000
M90.26 Osteopathy in other infectious diseases classified elsewhere (Lower leg)	0.002	0.998	0.000
M90.25 Osteopathy in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.002	0.998	0.000
M90.24 Osteopathy in other infectious diseases classified elsewhere (Hand)	0.002	0.998	0.000
M90.23 Osteopathy in other infectious diseases classified elsewhere (Forearm)	0.002	0.998	0.000
M90.22 Osteopathy in other infectious diseases classified elsewhere (Upper arm)	0.002	0.998	0.000
M90.21 Osteopathy in other infectious diseases classified elsewhere (Shoulder region)	0.002	0.998	0.000
M90.20 Osteopathy in other infectious diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
M90.39 Osteonecrosis in caisson disease (Site unspecified)	0.002	0.998	0.000
M90.38 Osteonecrosis in caisson disease (Other)	0.002	0.998	0.000
M90.37 Osteonecrosis in caisson disease (Ankle and foot)	0.002	0.998	0.000
M90.36 Osteonecrosis in caisson disease (Lower leg)	0.002	0.998	0.000
M90.35 Osteonecrosis in caisson disease (Pelvic region and thigh)	0.002	0.998	0.000
M90.34 Osteonecrosis in caisson disease (Hand)	0.002	0.998	0.000
M90.33 Osteonecrosis in caisson disease (Forearm)	0.002	0.998	0.000
M90.32 Osteonecrosis in caisson disease (Upper arm)	0.002	0.998	0.000
M90.31 Osteonecrosis in caisson disease (Shoulder region)	0.002	0.998	0.000
M90.30 Osteonecrosis in caisson disease (Multiple sites)	0.002	0.998	0.000
M90.49 Osteonecrosis due to haemoglobinopathy (Site unspecified)	0.002	0.998	0.000
M90.48 Osteonecrosis due to haemoglobinopathy (Other)	0.002	0.998	0.000
M90.47 Osteonecrosis due to haemoglobinopathy (Ankle and foot)	0.002	0.998	0.000
M90.46 Osteonecrosis due to haemoglobinopathy (Lower leg)	0.002	0.998	0.000
M90.45 Osteonecrosis due to haemoglobinopathy (Pelvic region and thigh)	0.002	0.998	0.000
M90.44 Osteonecrosis due to haemoglobinopathy (Hand)	0.002	0.998	0.000
M90.43 Osteonecrosis due to haemoglobinopathy (Forearm)	0.002	0.998	0.000
M90.42 Osteonecrosis due to haemoglobinopathy (Upper arm)	0.002	0.998	0.000
M90.41 Osteonecrosis due to haemoglobinopathy (Shoulder region)	0.002	0.998	0.000
M90.40 Osteonecrosis due to haemoglobinopathy (Multiple sites)	0.002	0.998	0.000
M90.59 Osteonecrosis in other diseases classified elsewhere (Site unspecified)	0.002	0.998	0.000
M90.58 Osteonecrosis in other diseases classified elsewhere (Other)	0.002	0.998	0.000
M90.57 Osteonecrosis in other diseases classified elsewhere (Ankle and foot)	0.002	0.998	0.000
M90.56 Osteonecrosis in other diseases classified elsewhere (Lower leg)	0.002	0.998	0.000
M90.55 Osteonecrosis in other diseases classified elsewhere (Pelvic region and thigh)	0.002	0.998	0.000
M90.54 Osteonecrosis in other diseases classified elsewhere (Hand)	0.002	0.998	0.000
M90.53 Osteonecrosis in other diseases classified elsewhere (Forearm)	0.002	0.998	0.000
M90.52 Osteonecrosis in other diseases classified elsewhere (Upper arm)	0.002	0.998	0.000
M90.51 Osteonecrosis in other diseases classified elsewhere (Shoulder region)	0.002	0.998	0.000
M90.50 Osteonecrosis in other diseases classified elsewhere (Multiple sites)	0.002	0.998	0.000
M90.69 Osteitis deformans in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.68 Osteitis deformans in neoplastic disease (Other)	0.002	0.998	0.000
M90.67 Osteitis deformans in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.66 Osteitis deformans in neoplastic disease (Lower leg)	0.002	0.998	0.000
M90.65 Osteitis deformans in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
M90.64 Osteitis deformans in neoplastic disease (Hand)	0.002	0.998	0.000
M90.63 Osteitis deformans in neoplastic disease (Forearm)	0.002	0.998	0.000
M90.62 Osteitis deformans in neoplastic disease (Upper arm)	0.002	0.998	0.000
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)	0.002	0.998	0.000
M90.60 Osteitis deformans in neoplastic disease (Multiple sites)	0.002	0.998	0.000
A48.4 Brazilian purpuric fever	0.002	0.998	0.000
A48.3 Toxic shock syndrome	0.002	0.998	0.000
A48.2 Nonpneumonic Legionnaires' disease [Pontiac fever]	0.002	0.998	0.000
A48.0 Gas gangrene	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
Y84.8 Other medical procedures	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations