TreeWAS – Variant ID: rs2280401

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y83.1 Surgical operation with implant of artificial internal device	0.188	0.812	0.000
M25.86 Other specified joint disorders (Lower leg)	0.025	0.975	0.000
M25.8 Other specified joint disorders	0.023	0.977	0.000
M25.84 Other specified joint disorders (Hand)	0.021	0.979	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.020	0.980	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.019	0.981	0.000
M25.83 Other specified joint disorders (Forearm)	0.018	0.982	0.000
C18.2 Ascending colon	0.000	0.982	0.018
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.017	0.983	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.017	0.983	0.000
M25.82 Other specified joint disorders (Upper arm)	0.017	0.983	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.017	0.983	0.000
M25.88 Other specified joint disorders (Other)	0.016	0.984	0.000
C18.5 Splenic flexure	0.000	0.984	0.016
C18 Malignant neoplasm of colon	0.000	0.985	0.015
N28.8 Other specified disorders of kidney and ureter	0.000	0.986	0.014
N72 Inflammatory disease of cervix uteri	0.000	0.987	0.013
C18.1 Appendix	0.000	0.987	0.013
C18.9 Colon, unspecified	0.000	0.988	0.012
C18.3 Hepatic flexure	0.000	0.988	0.012
C18.4 Transverse colon	0.000	0.988	0.012
M25 Other joint disorders, not elsewhere classified	0.011	0.989	0.000
M25.3 Other instability of joint	0.011	0.989	0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.011	0.989	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.000	0.989	0.011
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.990	0.010
Y83.4 Other reconstructive surgery	0.010	0.990	0.000
N70 Salpingitis and oophoritis	0.000	0.990	0.010
C18.6 Descending colon	0.000	0.990	0.010
M25.0 Haemarthrosis	0.010	0.990	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.990	0.010
M25.34 Other instability of joint (Hand)	0.010	0.990	0.000
M25.9 Joint disorder, unspecified	0.010	0.990	0.000
N76 Other inflammation of vagina and vulva	0.000	0.990	0.010
N71.9 Inflammatory disease of uterus, unspecified	0.000	0.991	0.009
N71 Inflammatory disease of uterus, except cervix	0.000	0.991	0.009
C18.8 Overlapping lesion of colon	0.000	0.991	0.009
M25.06 Haemarthrosis (Lower leg)	0.009	0.991	0.000
N76.0 Acute vaginitis	0.000	0.991	0.009
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.991	0.009
M25.4 Effusion of joint	0.009	0.991	0.000
Y83.3 Surgical operation with formation of external stoma	0.009	0.991	0.000
M25.33 Other instability of joint (Forearm)	0.009	0.991	0.000
C18.7 Sigmoid colon	0.000	0.991	0.009
M25.31 Other instability of joint (Shoulder region)	0.008	0.991	0.000
M25.37 Other instability of joint (Ankle and foot)	0.008	0.992	0.000
M25.94 Joint disorder, unspecified (Hand)	0.008	0.992	0.000
M25.36 Other instability of joint (Lower leg)	0.008	0.992	0.000
M25.2 Flail joint	0.008	0.992	0.000
M25.1 Fistula of joint	0.008	0.992	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.008	0.992	0.000
M25.39 Other instability of joint (Site unspecified)	0.008	0.992	0.000
M25.38 Other instability of joint (Other)	0.008	0.992	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.008	0.992	0.000
M25.32 Other instability of joint (Upper arm)	0.008	0.992	0.000
M25.30 Other instability of joint (Multiple sites)	0.008	0.992	0.000
N76.3 Subacute and chronic vulvitis	0.000	0.992	0.008
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.000	0.992	0.008
M25.45 Effusion of joint (Pelvic region and thigh)	0.008	0.992	0.000
Y83.9 Surgical procedure, unspecified	0.008	0.992	0.000
N75 Diseases of Bartholin's gland	0.000	0.992	0.008
N70.1 Chronic salpingitis and oophoritis	0.000	0.992	0.008
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
M25.09 Haemarthrosis (Site unspecified)	0.007	0.993	0.000
M25.08 Haemarthrosis (Other)	0.007	0.993	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.007	0.993	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.007	0.993	0.000
M25.04 Haemarthrosis (Hand)	0.007	0.993	0.000
M25.03 Haemarthrosis (Forearm)	0.007	0.993	0.000
M25.02 Haemarthrosis (Upper arm)	0.007	0.993	0.000
M25.01 Haemarthrosis (Shoulder region)	0.007	0.993	0.000
M25.00 Haemarthrosis (Multiple sites)	0.007	0.993	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.007	0.993	0.000
N75.0 Cyst of Bartholin's gland	0.000	0.993	0.007
M25.99 Joint disorder, unspecified (Site unspecified)	0.007	0.993	0.000
M25.98 Joint disorder, unspecified (Other)	0.007	0.993	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.007	0.993	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.007	0.993	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.007	0.993	0.000
N76.5 Ulceration of vagina	0.000	0.993	0.007
N76.1 Subacute and chronic vaginitis	0.000	0.993	0.007
M25.41 Effusion of joint (Shoulder region)	0.007	0.993	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.007	0.993	0.000
N70.0 Acute salpingitis and oophoritis	0.000	0.993	0.007
M25.47 Effusion of joint (Ankle and foot)	0.007	0.993	0.000
N76.6 Ulceration of vulva	0.000	0.993	0.007
N76.2 Acute vulvitis	0.000	0.993	0.007
Y83.5 Amputation of limb(s)	0.007	0.993	0.000
N76.8 Other specified inflammation of vagina and vulva	0.000	0.993	0.007
N76.4 Abscess of vulva	0.000	0.993	0.007
N73 Other female pelvic inflammatory diseases	0.000	0.993	0.007
M25.49 Effusion of joint (Site unspecified)	0.006	0.993	0.000
M25.48 Effusion of joint (Other)	0.006	0.993	0.000
M25.44 Effusion of joint (Hand)	0.006	0.993	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.006	0.993	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.993	0.006
M25.40 Effusion of joint (Multiple sites)	0.006	0.993	0.000
Y83.0 Surgical operation with transplant of whole organ	0.006	0.994	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.006	0.994	0.000
N71.0 Acute inflammatory disease of uterus	0.000	0.994	0.006
M25.19 Fistula of joint (Site unspecified)	0.006	0.994	0.000
M25.18 Fistula of joint (Other)	0.006	0.994	0.000
M25.17 Fistula of joint (Ankle and foot)	0.006	0.994	0.000
M25.16 Fistula of joint (Lower leg)	0.006	0.994	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.006	0.994	0.000
M25.14 Fistula of joint (Hand)	0.006	0.994	0.000
M25.13 Fistula of joint (Forearm)	0.006	0.994	0.000
M25.12 Fistula of joint (Upper arm)	0.006	0.994	0.000
M25.11 Fistula of joint (Shoulder region)	0.006	0.994	0.000
M25.10 Fistula of joint (Multiple sites)	0.006	0.994	0.000
M25.29 Flail joint (Site unspecified)	0.006	0.994	0.000
M25.28 Flail joint (Other)	0.006	0.994	0.000
M25.27 Flail joint (Ankle and foot)	0.006	0.994	0.000
M25.26 Flail joint (Lower leg)	0.006	0.994	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.006	0.994	0.000
M25.24 Flail joint (Hand)	0.006	0.994	0.000
M25.23 Flail joint (Forearm)	0.006	0.994	0.000
M25.22 Flail joint (Upper arm)	0.006	0.994	0.000
M25.21 Flail joint (Shoulder region)	0.006	0.994	0.000
M25.20 Flail joint (Multiple sites)	0.006	0.994	0.000
M25.43 Effusion of joint (Forearm)	0.006	0.994	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.994	0.006
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.000	0.994	0.006
N74.4 Female chlamydial pelvic inflammatory disease	0.000	0.994	0.006
N74.3 Female gonococcal pelvic inflammatory disease	0.000	0.994	0.006
N74.2 Female syphilitic pelvic inflammatory disease	0.000	0.994	0.006
N74.1 Female tuberculous pelvic inflammatory disease	0.000	0.994	0.006
N74.0 Tuberculous infection of cervix uteri	0.000	0.994	0.006
M25.42 Effusion of joint (Upper arm)	0.006	0.994	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.000	0.994	0.006
N75.8 Other diseases of Bartholin's gland	0.000	0.994	0.006
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.006	0.994	0.000
M25.46 Effusion of joint (Lower leg)	0.006	0.994	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.006	0.994	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.005	0.994	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.005	0.994	0.000
H04.2 Epiphora	0.006	0.994	0.000
N71.1 Chronic inflammatory disease of uterus	0.000	0.995	0.005
N73.0 Acute parametritis and pelvic cellulitis	0.000	0.995	0.005
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.005	0.995	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.000	0.995	0.005
N73.5 Female pelvic peritonitis, unspecified	0.000	0.995	0.005
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.005	0.995	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.000	0.995	0.005
N73.4 Female chronic pelvic peritonitis	0.000	0.995	0.005
N73.3 Female acute pelvic peritonitis	0.000	0.995	0.005
N73.2 Unspecified parametritis and pelvic cellulitis	0.000	0.995	0.005
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.005	0.995	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.995	0.005
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
M89.86 Other specified disorders of bone (Lower leg)	0.005	0.995	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.004	0.995	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.995	0.005
Y60.0 During surgical operation	0.000	0.995	0.005
C18.0 Caecum	0.000	0.995	0.004
S22.40 Multiple fractures of ribs (closed)	0.000	0.996	0.004
K55.2 Angiodysplasia of colon	0.000	0.996	0.004
D75.1 Secondary polycythaemia	0.000	0.996	0.004
M89.8 Other specified disorders of bone	0.004	0.996	0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.004	0.996	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.996	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.003
R05 Cough	0.004	0.996	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.003	0.997	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.000	0.997	0.003
Q85 Phakomatoses, not elsewhere classified	0.003	0.997	0.000
Y60.4 During endoscopic examination	0.000	0.997	0.003
I30.9 Acute pericarditis, unspecified	0.003	0.997	0.000
N73.6 Female pelvic peritoneal adhesions	0.000	0.997	0.003
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.997	0.000
Q80-Q89 Other congenital malformations	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.003	0.997	0.000
M89.84 Other specified disorders of bone (Hand)	0.003	0.997	0.000
M89.83 Other specified disorders of bone (Forearm)	0.003	0.997	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.003	0.997	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.003	0.997	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.003	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
S22.4 Multiple fractures of ribs	0.000	0.997	0.003
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.003	0.997	0.000
Q78.0 Osteogenesis imperfecta	0.003	0.997	0.000
K55.0 Acute vascular disorders of intestine	0.000	0.997	0.003
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.003	0.997	0.000
Y60.8 During other surgical and medical care	0.000	0.997	0.003
K31.8 Other specified diseases of stomach and duodenum	0.003	0.997	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.003	0.997	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.997	0.003
Y60.9 During unspecified surgical and medical care	0.000	0.997	0.003
Y60.7 During administration of enema	0.000	0.997	0.003
Y60.6 During aspiration, puncture and other catheterisation	0.000	0.997	0.003
Y60.3 During injection or immunisation	0.000	0.997	0.003
Y60.2 During kidney dialysis or other perfusion	0.000	0.997	0.003
Y60.1 During infusion or transfusion	0.000	0.997	0.003
H83.0 Labyrinthitis	0.003	0.997	0.000
Q85.1 Tuberous sclerosis	0.003	0.997	0.000
Z33 Pregnant state, incidental	0.003	0.997	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.003	0.997	0.000
Y60.5 During heart catheterisation	0.000	0.997	0.002
Q82 Other congenital malformations of skin	0.002	0.997	0.000
Q85.9 Phakomatosis, unspecified	0.002	0.997	0.000
K63.1 Perforation of intestine (nontraumatic)	0.000	0.997	0.002
Q83 Congenital malformations of breast	0.002	0.997	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
Q82.2 Mastocytosis	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
S22.41 Multiple fractures of ribs (open)	0.000	0.998	0.002
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.002	0.998	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.002	0.998	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.002	0.998	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.002	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.002	0.998	0.000
K55 Vascular disorders of intestine	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
Z97.8 Presence of other specified devices	0.000	0.998	0.002
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
R80 Isolated proteinuria	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.998	0.002
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
N25-N29 Other disorders of kidney and ureter	0.000	0.998	0.002
S02.50 Fracture of tooth (closed)	0.002	0.998	0.000
Q83.1 Accessory breast	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.998	0.002
Q82.9 Congenital malformation of skin, unspecified	0.002	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.002	0.998	0.000
Q82.3 Incontinentia pigmenti	0.002	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.002	0.998	0.000
Q82.0 Hereditary lymphoedema	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
Q83.9 Congenital malformation of breast, unspecified	0.002	0.998	0.000
Q83.8 Other congenital malformations of breast	0.002	0.998	0.000
Q83.3 Accessory nipple	0.002	0.998	0.000
Q83.2 Absent nipple	0.002	0.998	0.000
Q83.0 Congenital absence of breast with absent nipple	0.002	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.4 Achondroplasia	0.002	0.998	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.002	0.998	0.000
Q78.8 Other specified osteochondrodysplasias	0.002	0.998	0.000
Q78.6 Multiple congenital exostoses	0.002	0.998	0.000
Q78.5 Metaphyseal dysplasia	0.002	0.998	0.000
Q78.4 Enchondromatosis	0.002	0.998	0.000
Q78.3 Progressive diaphyseal dysplasia	0.002	0.998	0.000
Q78.2 Osteopetrosis	0.002	0.998	0.000
Q78.1 Polyostotic fibrous dysplasia	0.002	0.998	0.000
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
Q80.9 Congenital ichthyosis, unspecified	0.002	0.998	0.000
Q80.8 Other congenital ichthyosis	0.002	0.998	0.000
Q80.4 Harlequin foetus	0.002	0.998	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.002	0.998	0.000
Q80.2 Lamellar ichthyosis	0.002	0.998	0.000
Q80.1 X-linked ichthyosis	0.002	0.998	0.000
Q80.0 Ichthyosis vulgaris	0.002	0.998	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.002	0.998	0.000
Q81.8 Other epidermolysis bullosa	0.002	0.998	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.002	0.998	0.000
Q81.1 Epidermolysis bullosa letalis	0.002	0.998	0.000
Q81.0 Epidermolysis bullosa simplex	0.002	0.998	0.000
Q84.9 Congenital malformation of integument, unspecified	0.002	0.998	0.000
Q84.8 Other specified congenital malformations of integument	0.002	0.998	0.000
Q84.6 Other congenital malformations of nails	0.002	0.998	0.000
Q84.5 Enlarged and hypertrophic nails	0.002	0.998	0.000
Q84.4 Congenital leukonychia	0.002	0.998	0.000
Q84.3 Anonychia	0.002	0.998	0.000
Q84.2 Other congenital malformations of hair	0.002	0.998	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.002	0.998	0.000
Q84.0 Congenital alopecia	0.002	0.998	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.002	0.998	0.000
Q86.2 Dysmorphism due to warfarin	0.002	0.998	0.000
Q86.1 Foetal hydantoin syndrome	0.002	0.998	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.002	0.998	0.000
H93.1 Tinnitus	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.998	0.002
S22.3 Fracture of rib	0.000	0.998	0.002
G40.7 Petit mal, unspecified, without grand mal seizures	0.002	0.998	0.000
K55.1 Chronic vascular disorders of intestine	0.000	0.998	0.002
Q89.9 Congenital malformation, unspecified	0.002	0.998	0.000
Q89.8 Other specified congenital malformations	0.002	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q89.4 Conjoined twins	0.002	0.998	0.000
Q89.3 Situs inversus	0.002	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.002	0.998	0.000
Q89.0 Congenital malformations of spleen	0.002	0.998	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.998	0.002
G40 Epilepsy	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
N25 Disorders resulting from impaired renal tubular function	0.000	0.998	0.002
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.998	0.002
K55.8 Other vascular disorders of intestine	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.002	0.998	0.000
F99 Mental disorder, not otherwise specified	0.002	0.998	0.000
Q66.7 Pes cavus	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
Q05 Spina bifida	0.002	0.998	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
N28.1 Cyst of kidney, acquired	0.000	0.998	0.002
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.000	0.998	0.002
Q03 Congenital hydrocephalus	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.000	0.998	0.002
G82.4 Spastic tetraplegia	0.002	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.998	0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere	0.000	0.998	0.002
G40.8 Other epilepsy	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.000	0.998	0.002
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
X58.9 Unspecified place	0.002	0.998	0.000
Q06 Other congenital malformations of spinal cord	0.002	0.998	0.000
Q04 Other congenital malformations of brain	0.002	0.998	0.000
Q01 Encephalocele	0.002	0.998	0.000
Q00 Anencephaly and similar malformations	0.002	0.998	0.000
Q02 Microcephaly	0.002	0.998	0.000
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.002	0.998	0.000
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.998	0.000
S22.2 Fracture of sternum	0.001	0.998	0.001
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.998	0.002
G83.8 Other specified paralytic syndromes	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.000	0.998	0.002
Q21.1 Atrial septal defect	0.002	0.998	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.002	0.998	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.002	0.998	0.000
Q77.6 Chondroectodermal dysplasia	0.002	0.998	0.000
Q77.5 Diastrophic dysplasia	0.002	0.998	0.000
Q77.3 Chondrodysplasia punctata	0.002	0.998	0.000
Q77.2 Short rib syndrome	0.002	0.998	0.000
Q77.1 Thanatophoric short stature	0.002	0.998	0.000
Q77.0 Achondrogenesis	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.000	0.998	0.001
H66.3 Other chronic suppurative otitis media	0.000	0.998	0.002
H93.9 Disorder of ear, unspecified	0.002	0.998	0.000
G40.5 Special epileptic syndromes	0.002	0.998	0.000
K59.9 Functional intestinal disorder, unspecified	0.002	0.998	0.000
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
Q03.0 Malformations of aqueduct of Sylvius	0.001	0.998	0.000
H83 Other diseases of inner ear	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.002	0.998	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
N25.9 Disorder resulting from impaired renal tubular function, unspecified	0.000	0.998	0.001
N25.1 Nephrogenic diabetes insipidus	0.000	0.998	0.001
N25.0 Renal osteodystrophy	0.000	0.998	0.001
Q65 Congenital deformities of hip	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
F51.0 Nonorganic insomnia	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.001	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.001	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.001	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.001	0.998	0.000
Q54.0 Hypospadias, balanic	0.002	0.998	0.000
Q66.9 Congenital deformity of feet, unspecified	0.001	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.001	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.001	0.998	0.000
Q66.1 Talipes calcaneovarus	0.001	0.998	0.000
Q66.0 Talipes equinovarus	0.001	0.998	0.000
Q14.1 Congenital malformation of retina	0.001	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.001	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.001	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.001	0.998	0.000
M89.2 Other disorders of bone development and growth	0.001	0.998	0.000
M89.1 Epiphyseal arrest	0.001	0.998	0.000
Q03.9 Congenital hydrocephalus, unspecified	0.001	0.998	0.000
Q03.8 Other congenital hydrocephalus	0.001	0.998	0.000
Q03.1 Atresia of foramina of Magendie and Luschka	0.001	0.998	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.998	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.998	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.001	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.001	0.998	0.000
N29.8 Other disorders of kidney and ureter in other diseases classified elsewhere	0.000	0.998	0.001
N29.1 Other disorders of kidney and ureter in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
N29.0 Late syphilis of kidney	0.000	0.998	0.001
Q25 Congenital malformations of great arteries	0.001	0.998	0.000
Q74.1 Congenital malformation of knee	0.001	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.001	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.001	0.998	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.001	0.998	0.000
Q68.4 Congenital bowing of tibia and fibula	0.001	0.998	0.000
Q68.3 Congenital bowing of femur	0.001	0.998	0.000
Q68.2 Congenital deformity of knee	0.001	0.998	0.000
Q68.1 Congenital deformity of hand	0.001	0.998	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.001	0.998	0.000
Q69.9 Polydactyly, unspecified	0.001	0.998	0.000
Q69.2 Accessory toe(s)	0.001	0.998	0.000
Q69.1 Accessory thumb(s)	0.001	0.998	0.000
Q69.0 Accessory finger(s)	0.001	0.998	0.000
Q70.9 Syndactyly, unspecified	0.001	0.998	0.000
Q70.4 Polysyndactyly	0.001	0.998	0.000
Q70.3 Webbed toes	0.001	0.998	0.000
Q70.2 Fused toes	0.001	0.998	0.000
Q70.1 Webbed fingers	0.001	0.998	0.000
Q70.0 Fused fingers	0.001	0.998	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.001	0.998	0.000
Q71.8 Other reduction defects of upper limb(s)	0.001	0.998	0.000
Q71.6 Lobster-claw hand	0.001	0.998	0.000
Q71.5 Longitudinal reduction defect of ulna	0.001	0.998	0.000
Q71.4 Longitudinal reduction defect of radius	0.001	0.998	0.000
Q71.3 Congenital absence of hand and finger(s)	0.001	0.998	0.000
Q71.2 Congenital absence of both forearm and hand	0.001	0.998	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.001	0.998	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.001	0.998	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.001	0.998	0.000
Q72.8 Other reduction defects of lower limb(s)	0.001	0.998	0.000
Q72.7 Split foot	0.001	0.998	0.000
Q72.6 Longitudinal reduction defect of fibula	0.001	0.998	0.000
Q72.5 Longitudinal reduction defect of tibia	0.001	0.998	0.000
Q72.4 Longitudinal reduction defect of femur	0.001	0.998	0.000
Q72.3 Congenital absence of foot and toe(s)	0.001	0.998	0.000
Q72.2 Congenital absence of both lower leg and foot	0.001	0.998	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.001	0.998	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.001	0.998	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.001	0.998	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.001	0.998	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.001	0.998	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.001	0.998	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.001	0.998	0.000
Q74.3 Arthrogryposis multiplex congenita	0.001	0.998	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.001	0.998	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.001	0.998	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.001	0.998	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.001	0.998	0.000
Q75.5 Oculomandibular dysostosis	0.001	0.998	0.000
Q75.4 Mandibulofacial dysostosis	0.001	0.998	0.000
Q75.3 Macrocephaly	0.001	0.998	0.000
Q75.2 Hypertelorism	0.001	0.998	0.000
Q75.1 Craniofacial dysostosis	0.001	0.998	0.000
Q75.0 Craniosynostosis	0.001	0.998	0.000
Z74.0 Reduced mobility	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.001	0.998	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.001	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.001	0.998	0.000
Q35 Cleft palate	0.001	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.998	0.000
S22.21 Fracture of sternum (open)	0.001	0.998	0.001
Q00.2 Iniencephaly	0.001	0.998	0.000
Q00.1 Craniorachischisis	0.001	0.998	0.000
Q00.0 Anencephaly	0.001	0.998	0.000
Q01.9 Encephalocele, unspecified	0.001	0.998	0.000
Q01.8 Encephalocele of other sites	0.001	0.998	0.000
Q01.2 Occipital encephalocele	0.001	0.998	0.000
Q01.1 Nasofrontal encephalocele	0.001	0.998	0.000
Q01.0 Frontal encephalocele	0.001	0.998	0.000
Q04.9 Congenital malformation of brain, unspecified	0.001	0.998	0.000
Q04.8 Other specified congenital malformations of brain	0.001	0.998	0.000
Q04.6 Congenital cerebral cysts	0.001	0.998	0.000
Q04.5 Megalencephaly	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations