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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2281816
log Bayes Factor = 11.9496
Chromosome 6   position 33,772,335  (GRCh37) Explore rs2281816 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K90.0 Coeliac disease
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
M05 Seropositive rheumatoid arthritis
0.999 0.001 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.998 0.002 0.000
M05-M14 Inflammatory polyarthropathies
0.998 0.002 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.995 0.005 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.988 0.012 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.017 0.983
M06.3 Rheumatoid nodule
0.981 0.019 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.020 0.980
T42.4 Benzodiazepines
0.000 0.026 0.974
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.026 0.974
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.040 0.960
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.047 0.953
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.940 0.060 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.063 0.937
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.929 0.071 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.072 0.928
M06.34 Rheumatoid nodule (Hand)
0.925 0.075 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.085 0.915
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.887 0.113 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.118 0.882
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.124 0.876
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.875 0.125 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.871 0.129 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.129 0.871
M06.32 Rheumatoid nodule (Upper arm)
0.865 0.135 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.146 0.854
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.851 0.149 0.000
M05.1 Rheumatoid lung disease
0.840 0.160 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.170 0.830
K90 Intestinal malabsorption
0.000 0.172 0.828
T42.0 Hydantoin derivatives
0.000 0.172 0.827
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.823 0.177 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.181 0.819
M06.4 Inflammatory polyarthropathy
0.817 0.183 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.812 0.188 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.189 0.811
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.799 0.201 0.000
T45.5 Anticoagulants
0.000 0.206 0.794
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.208 0.792
K90.9 Intestinal malabsorption, unspecified
0.000 0.217 0.783
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.217 0.782
M06.30 Rheumatoid nodule (Multiple sites)
0.776 0.224 0.000
T45.2 Vitamins, not elsewhere classified
0.000 0.226 0.774
M08 Juvenile arthritis
0.770 0.230 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.233 0.767
M06.33 Rheumatoid nodule (Forearm)
0.766 0.234 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.756 0.244 0.000
M11 Other crystal arthropathies
0.754 0.246 0.000
M05.2 Rheumatoid vasculitis
0.746 0.254 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.734 0.266 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.733 0.267 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.727 0.273 0.000
M10 Gout
0.725 0.275 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.279 0.721
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.717 0.283 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.716 0.284 0.000
M05.0 Felty's syndrome
0.716 0.284 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.715 0.285 0.000
M05.8 Other seropositive rheumatoid arthritis
0.711 0.288 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.711 0.289 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.295 0.705
M06.39 Rheumatoid nodule (Site unspecified)
0.704 0.296 0.000
M06.38 Rheumatoid nodule (Other)
0.704 0.296 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.704 0.296 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.704 0.296 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.704 0.296 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.297 0.703
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.298 0.702
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.298 0.702
T42.2 Succinimides and oxazolidinediones
0.000 0.298 0.702
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.301 0.699
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.301 0.699
T43.9 Psychotropic drug, unspecified
0.000 0.302 0.698
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.302 0.698
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.302 0.698
M12 Other specific arthropathies
0.695 0.305 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.312 0.688
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.312 0.688
T46.7 Peripheral vasodilators
0.000 0.312 0.688
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.312 0.688
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.314 0.686
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.684 0.316 0.000
T36 Poisoning by systemic antibiotics
0.000 0.316 0.684
M06.98 Rheumatoid arthritis, unspecified (Other)
0.679 0.320 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.328 0.672
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.328 0.672
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.328 0.672
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.328 0.672
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.328 0.672
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.328 0.672
T44.0 Anticholinesterase agents
0.000 0.328 0.672
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.328 0.672
M06.46 Inflammatory polyarthropathy (Lower leg)
0.671 0.329 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.330 0.670
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.336 0.663
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.341 0.659
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.344 0.656
T45.8 Other primarily systemic and haematological agents
0.000 0.344 0.656
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.344 0.656
T45.6 Fibrinolysis-affecting drugs
0.000 0.344 0.656
T45.4 Iron and its compounds
0.000 0.344 0.656
T45.3 Enzymes, not elsewhere classified
0.000 0.344 0.656
T43.6 Psychostimulants with abuse potential
0.000 0.352 0.648
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.360 0.640
T40.4 Other synthetic narcotics
0.000 0.372 0.628
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.376 0.624
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.621 0.379 0.000
M10.0 Idiopathic gout
0.613 0.387 0.000
M11.9 Crystal arthropathy, unspecified
0.609 0.391 0.000
M08.0 Juvenile rheumatoid arthritis
0.607 0.393 0.000
K90.8 Other intestinal malabsorption
0.000 0.397 0.603
M05.18 Rheumatoid lung disease (Other)
0.602 0.397 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.602 0.397 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.602 0.397 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.602 0.397 0.000
M05.14 Rheumatoid lung disease (Hand)
0.602 0.397 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.602 0.397 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.602 0.397 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.602 0.397 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.602 0.397 0.000
M14 Arthropathies in other diseases classified elsewhere
0.596 0.404 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.405 0.595
T42.3 Barbiturates
0.000 0.406 0.594
K90.3 Pancreatic steatorrhoea
0.000 0.406 0.593
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.406 0.593
K90.1 Tropical sprue
0.000 0.406 0.593
T42.1 Iminostilbenes
0.000 0.408 0.592
M06.48 Inflammatory polyarthropathy (Other)
0.585 0.414 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.585 0.414 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.585 0.414 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.585 0.414 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.585 0.414 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.585 0.414 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.585 0.414 0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.417 0.582
M06.0 Seronegative rheumatoid arthritis
0.577 0.423 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.571 0.429 0.000
M07 Psoriatic and enteropathic arthropathies
0.570 0.430 0.000
T46.1 Calcium-channel blockers
0.000 0.433 0.566
M05.29 Rheumatoid vasculitis (Site unspecified)
0.565 0.435 0.000
T40.6 Other and unspecified narcotics
0.000 0.438 0.562
T50.4 Drugs affecting uric acid metabolism
0.000 0.444 0.556
M08.9 Juvenile arthritis, unspecified
0.552 0.448 0.000
M08.8 Other juvenile arthritis
0.552 0.448 0.000
M08.4 Pauciarticular juvenile arthritis
0.552 0.448 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.552 0.448 0.000
M08.2 Juvenile arthritis with systemic onset
0.552 0.448 0.000
M08.1 Juvenile ankylosing spondylitis
0.552 0.448 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.550 0.450 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.450 0.550
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.450 0.550
T47.7 Emetics
0.000 0.450 0.550
T47.6 Antidiarrhoeal drugs
0.000 0.450 0.550
T47.5 Digestants
0.000 0.450 0.550
T47.4 Other laxatives
0.000 0.450 0.550
T47.3 Saline and osmotic laxatives
0.000 0.450 0.550
T47.0 Histamine H(2)-receptor antagonists
0.000 0.450 0.550
M11.1 Familial chondrocalcinosis
0.540 0.460 0.000
M11.0 Hydroxyapatite deposition disease
0.540 0.460 0.000
T45.0 Antiallergic and antiemetic drugs
0.000 0.462 0.538
M05.28 Rheumatoid vasculitis (Other)
0.535 0.465 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.535 0.465 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.535 0.465 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.535 0.465 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.535 0.465 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.535 0.465 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.535 0.465 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.535 0.465 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.535 0.465 0.000
M11.8 Other specified crystal arthropathies
0.535 0.465 0.000
M10.4 Other secondary gout
0.520 0.480 0.000
M10.3 Gout due to impairment of renal function
0.520 0.480 0.000
M10.2 Drug-induced gout
0.520 0.480 0.000
M10.1 Lead-induced gout
0.520 0.480 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.518 0.481 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.483 0.517
T40.8 Lysergide [LSD]
0.000 0.483 0.517
T40.7 Cannabis (derivatives)
0.000 0.483 0.517
T40.1 Heroin
0.000 0.483 0.517
T40.0 Opium
0.000 0.483 0.517
M06.19 Adult-onset Still's disease (Site unspecified)
0.514 0.486 0.000
M06.18 Adult-onset Still's disease (Other)
0.514 0.486 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.514 0.486 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.514 0.486 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.514 0.486 0.000
M06.14 Adult-onset Still's disease (Hand)
0.514 0.486 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.514 0.486 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.514 0.486 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.514 0.486 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.514 0.486 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.514 0.486 0.000
M06.28 Rheumatoid bursitis (Other)
0.514 0.486 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.514 0.486 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.514 0.486 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.514 0.486 0.000
M06.24 Rheumatoid bursitis (Hand)
0.514 0.486 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.514 0.486 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.514 0.486 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.514 0.486 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.514 0.486 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.514 0.486 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.514 0.486 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.514 0.486 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.514 0.486 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.514 0.486 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.514 0.486 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.514 0.486 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.514 0.486 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.514 0.486 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.514 0.486 0.000
M05.09 Felty's syndrome (Site unspecified)
0.513 0.486 0.000
M05.08 Felty's syndrome (Other)
0.513 0.486 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.513 0.486 0.000
M05.06 Felty's syndrome (Lower leg)
0.513 0.486 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.513 0.486 0.000
M05.04 Felty's syndrome (Hand)
0.513 0.486 0.000
M05.03 Felty's syndrome (Forearm)
0.513 0.486 0.000
M05.02 Felty's syndrome (Upper arm)
0.513 0.486 0.000
M05.01 Felty's syndrome (Shoulder region)
0.513 0.486 0.000
M05.00 Felty's syndrome (Multiple sites)
0.513 0.486 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.513 0.486 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.513 0.486 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.513 0.486 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.513 0.486 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.513 0.486 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.513 0.486 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.513 0.486 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.513 0.486 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.513 0.486 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.513 0.486 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.513 0.487 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.513 0.487 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.513 0.487 0.000
M09.0 Juvenile arthritis in psoriasis
0.513 0.487 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.510 0.490 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.510 0.490 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.510 0.490 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.510 0.490 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.510 0.490 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.510 0.490 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.510 0.490 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.510 0.490 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.510 0.490 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.505 0.494 0.000
T41.5 Therapeutic gases
0.000 0.495 0.505
T41.4 Anaesthetic, unspecified
0.000 0.495 0.505
T41.3 Local anaesthetics
0.000 0.495 0.505
T41.2 Other and unspecified general anaesthetics
0.000 0.495 0.505
T41.1 Intravenous anaesthetics
0.000 0.495 0.505
T41.0 Inhaled anaesthetics
0.000 0.495 0.505
M11.96 Crystal arthropathy, unspecified (Lower leg)
0.505 0.495 0.000
M11.2 Other chondrocalcinosis
0.502 0.497 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.498 0.501
T48.5 Anti-common-cold drugs
0.000 0.498 0.501
T48.4 Expectorants
0.000 0.498 0.501
T48.3 Antitussives
0.000 0.498 0.501
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.498 0.501
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.498 0.501
T48.0 Oxytocic drugs
0.000 0.498 0.501
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.499 0.501
T37.5 Antiviral drugs
0.000 0.499 0.501
T37.4 Anthelminthics
0.000 0.499 0.501
T37.3 Other antiprotozoal drugs
0.000 0.499 0.501
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.499 0.501
T37.1 Antimycobacterial drugs
0.000 0.499 0.501
T37.0 Sulphonamides
0.000 0.499 0.501
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.499 0.501
M12.3 Palindromic rheumatism
0.501 0.499 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.500 0.500
M12.5 Traumatic arthropathy
0.498 0.501 0.000
M12.4 Intermittent hydrarthrosis
0.498 0.501 0.000
M12.1 Kaschin-Beck disease
0.498 0.501 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.498 0.501 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.504 0.496
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.504 0.495
T50.7 Analeptics and opioid receptor antagonists
0.000 0.508 0.492
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.508 0.492
T50.5 Appetite depressants
0.000 0.508 0.492
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.508 0.492
T50.1 Loop [high-ceiling] diuretics
0.000 0.508 0.492
T50.0 Mineralocorticoids and their antagonists
0.000 0.508 0.492
T36.9 Systemic antibiotic, unspecified
0.000 0.509 0.491
T36.8 Other systemic antibiotics
0.000 0.509 0.491
T36.7 Antifungal antibiotics, systemically used
0.000 0.509 0.491
T36.6 Rifamycins
0.000 0.509 0.491
T36.5 Aminoglycosides
0.000 0.509 0.491
T36.4 Tetracyclines
0.000 0.509 0.491
T36.3 Macrolides
0.000 0.509 0.491
T36.2 Chloramphenicol group
0.000 0.509 0.491
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.509 0.491
M08.00 Juvenile rheumatoid arthritis (Multiple sites)
0.490 0.510 0.000
T38.1 Thyroid hormones and substitutes
0.000 0.523 0.477
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.523 0.477
T49.9 Topical agent, unspecified
0.000 0.524 0.476
T49.8 Other topical agents
0.000 0.524 0.476
T49.7 Dental drugs, topically applied
0.000 0.524 0.476
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.524 0.476
T49.5 Ophthalmological drugs and preparations
0.000 0.524 0.476
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.524 0.476
T49.3 Emollients, demulcents and protectants
0.000 0.524 0.476
T49.2 Local astringents and local detergents
0.000 0.524 0.476
T49.1 Antipruritics
0.000 0.524 0.476
T36.0 Penicillins
0.000 0.530 0.470
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.538 0.462
T38.9 Other and unspecified hormone antagonists
0.000 0.541 0.459
T38.7 Androgens and anabolic congeners
0.000 0.541 0.459
T38.5 Other oestrogens and progestogens
0.000 0.541 0.459
T38.4 Oral contraceptives
0.000 0.541 0.459
T38.2 Antithyroid drugs
0.000 0.541 0.459
T38.0 Glucocorticoids and synthetic analogues
0.000 0.541 0.459
T39.0 Salicylates
0.000 0.542 0.458
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.542 0.457
T47.2 Stimulant laxatives
0.000 0.544 0.456
M10.06 Idiopathic gout (Lower leg)
0.455 0.545 0.000
T40.5 Cocaine
0.000 0.546 0.454
M12.2 Villonodular synovitis (pigmented)
0.451 0.549 0.000
M10.08 Idiopathic gout (Other)
0.440 0.560 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.440 0.560 0.000
M10.04 Idiopathic gout (Hand)
0.440 0.560 0.000
M10.03 Idiopathic gout (Forearm)
0.440 0.560 0.000
M10.02 Idiopathic gout (Upper arm)
0.440 0.560 0.000
M10.01 Idiopathic gout (Shoulder region)
0.440 0.560 0.000
M10.00 Idiopathic gout (Multiple sites)
0.440 0.560 0.000
T40.2 Other opioids
0.000 0.563 0.437
M11.99 Crystal arthropathy, unspecified (Site unspecified)
0.436 0.563 0.000
M11.98 Crystal arthropathy, unspecified (Other)
0.436 0.563 0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)
0.436 0.563 0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)
0.436 0.563 0.000
M11.94 Crystal arthropathy, unspecified (Hand)
0.436 0.563 0.000
M11.93 Crystal arthropathy, unspecified (Forearm)
0.436 0.563 0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)
0.436 0.563 0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)
0.436 0.563 0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)
0.436 0.563 0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)
0.435 0.564 0.000
M08.08 Juvenile rheumatoid arthritis (Other)
0.435 0.564 0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)
0.435 0.564 0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)
0.435 0.564 0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)
0.435 0.564 0.000
M08.04 Juvenile rheumatoid arthritis (Hand)
0.435 0.564 0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)
0.435 0.564 0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)
0.435 0.564 0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)
0.435 0.564 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.565 0.434
T40.3 Methadone
0.000 0.568 0.432
M14.8 Arthropathies in other specified diseases classified elsewhere
0.427 0.572 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.427 0.572 0.000
M14.4 Arthropathy in amyloidosis
0.427 0.572 0.000
M14.3 Lipoid dermatoarthritis
0.427 0.572 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.427 0.572 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.427 0.572 0.000
T39.4 Antirheumatics, not elsewhere classified
0.000 0.573 0.427
T39.2 Pyrazolone derivatives
0.000 0.573 0.427
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.421 0.579 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.416 0.584 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.413 0.586 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.413 0.586 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.413 0.586 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.413 0.586 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.413 0.586 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.413 0.586 0.000
M14.2 Diabetic arthropathy
0.409 0.591 0.000
M07.6 Other enteropathic arthropathies
0.409 0.591 0.000
M07.5 Arthropathy in ulcerative colitis
0.409 0.591 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.409 0.591 0.000
M07.2 Psoriatic spondylitis
0.409 0.591 0.000
M07.1 Arthritis mutilans
0.409 0.591 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.409 0.591 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.405 0.595 0.000
M08.19 Juvenile ankylosing spondylitis (Site unspecified)
0.396 0.604 0.000
M08.18 Juvenile ankylosing spondylitis (Other)
0.396 0.604 0.000
M08.17 Juvenile ankylosing spondylitis (Ankle and foot)
0.396 0.604 0.000
M08.16 Juvenile ankylosing spondylitis (Lower leg)
0.396 0.604 0.000
M08.15 Juvenile ankylosing spondylitis (Pelvic region and thigh)
0.396 0.604 0.000
M08.14 Juvenile ankylosing spondylitis (Hand)
0.396 0.604 0.000
M08.13 Juvenile ankylosing spondylitis (Forearm)
0.396 0.604 0.000
M08.12 Juvenile ankylosing spondylitis (Upper arm)
0.396 0.604 0.000
M08.11 Juvenile ankylosing spondylitis (Shoulder region)
0.396 0.604 0.000
M08.10 Juvenile ankylosing spondylitis (Multiple sites)
0.396 0.604 0.000
M08.29 Juvenile arthritis with systemic onset (Site unspecified)
0.396 0.604 0.000
M08.28 Juvenile arthritis with systemic onset (Other)
0.396 0.604 0.000
M08.27 Juvenile arthritis with systemic onset (Ankle and foot)
0.396 0.604 0.000
M08.26 Juvenile arthritis with systemic onset (Lower leg)
0.396 0.604 0.000
M08.25 Juvenile arthritis with systemic onset (Pelvic region and thigh)
0.396 0.604 0.000
M08.24 Juvenile arthritis with systemic onset (Hand)
0.396 0.604 0.000
M08.23 Juvenile arthritis with systemic onset (Forearm)
0.396 0.604 0.000
M08.22 Juvenile arthritis with systemic onset (Upper arm)
0.396 0.604 0.000
M08.21 Juvenile arthritis with systemic onset (Shoulder region)
0.396 0.604 0.000
M08.20 Juvenile arthritis with systemic onset (Multiple sites)
0.396 0.604 0.000
M08.39 Juvenile polyarthritis (seronegative) (Site unspecified)
0.396 0.604 0.000
M08.38 Juvenile polyarthritis (seronegative) (Other)
0.396 0.604 0.000
M08.37 Juvenile polyarthritis (seronegative) (Ankle and foot)
0.396 0.604 0.000
M08.36 Juvenile polyarthritis (seronegative) (Lower leg)
0.396 0.604 0.000
M08.35 Juvenile polyarthritis (seronegative) (Pelvic region and thigh)
0.396 0.604 0.000
M08.34 Juvenile polyarthritis (seronegative) (Hand)
0.396 0.604 0.000
M08.33 Juvenile polyarthritis (seronegative) (Forearm)
0.396 0.604 0.000
M08.32 Juvenile polyarthritis (seronegative) (Upper arm)
0.396 0.604 0.000
M08.31 Juvenile polyarthritis (seronegative) (Shoulder region)
0.396 0.604 0.000
M08.30 Juvenile polyarthritis (seronegative) (Multiple sites)
0.396 0.604 0.000
M08.49 Pauciarticular juvenile arthritis (Site unspecified)
0.396 0.604 0.000
M08.48 Pauciarticular juvenile arthritis (Other)
0.396 0.604 0.000
M08.47 Pauciarticular juvenile arthritis (Ankle and foot)
0.396 0.604 0.000
M08.46 Pauciarticular juvenile arthritis (Lower leg)
0.396 0.604 0.000
M08.45 Pauciarticular juvenile arthritis (Pelvic region and thigh)
0.396 0.604 0.000
M08.44 Pauciarticular juvenile arthritis (Hand)
0.396 0.604 0.000
M08.43 Pauciarticular juvenile arthritis (Forearm)
0.396 0.604 0.000
M08.42 Pauciarticular juvenile arthritis (Upper arm)
0.396 0.604 0.000
M08.41 Pauciarticular juvenile arthritis (Shoulder region)
0.396 0.604 0.000
M08.40 Pauciarticular juvenile arthritis (Multiple sites)
0.396 0.604 0.000
M08.89 Other juvenile arthritis (Site unspecified)
0.396 0.604 0.000
M08.88 Other juvenile arthritis (Other)
0.396 0.604 0.000
M08.87 Other juvenile arthritis (Ankle and foot)
0.396 0.604 0.000
M08.86 Other juvenile arthritis (Lower leg)
0.396 0.604 0.000
M08.85 Other juvenile arthritis (Pelvic region and thigh)
0.396 0.604 0.000
M08.84 Other juvenile arthritis (Hand)
0.396 0.604 0.000
M08.83 Other juvenile arthritis (Forearm)
0.396 0.604 0.000
M08.82 Other juvenile arthritis (Upper arm)
0.396 0.604 0.000
M08.81 Other juvenile arthritis (Shoulder region)
0.396 0.604 0.000
M08.80 Other juvenile arthritis (Multiple sites)
0.396 0.604 0.000
M08.99 Juvenile arthritis, unspecified (Site unspecified)
0.396 0.604 0.000
M08.98 Juvenile arthritis, unspecified (Other)
0.396 0.604 0.000
M08.97 Juvenile arthritis, unspecified (Ankle and foot)
0.396 0.604 0.000
M08.96 Juvenile arthritis, unspecified (Lower leg)
0.396 0.604 0.000
M08.95 Juvenile arthritis, unspecified (Pelvic region and thigh)
0.396 0.604 0.000
M08.94 Juvenile arthritis, unspecified (Hand)
0.396 0.604 0.000
M08.93 Juvenile arthritis, unspecified (Forearm)
0.396 0.604 0.000
M08.92 Juvenile arthritis, unspecified (Upper arm)
0.396 0.604 0.000
M08.91 Juvenile arthritis, unspecified (Shoulder region)
0.396 0.604 0.000
M08.90 Juvenile arthritis, unspecified (Multiple sites)
0.396 0.604 0.000
M12.88 Other specific arthropathies, not elsewhere classified (Other)
0.392 0.608 0.000
M11.09 Hydroxyapatite deposition disease (Site unspecified)
0.387 0.612 0.000
M11.08 Hydroxyapatite deposition disease (Other)
0.387 0.612 0.000
M11.07 Hydroxyapatite deposition disease (Ankle and foot)
0.387 0.612 0.000
M11.06 Hydroxyapatite deposition disease (Lower leg)
0.387 0.612 0.000
M11.05 Hydroxyapatite deposition disease (Pelvic region and thigh)
0.387 0.612 0.000
M11.04 Hydroxyapatite deposition disease (Hand)
0.387 0.612 0.000
M11.03 Hydroxyapatite deposition disease (Forearm)
0.387 0.612 0.000
M11.02 Hydroxyapatite deposition disease (Upper arm)
0.387 0.612 0.000
M11.01 Hydroxyapatite deposition disease (Shoulder region)
0.387 0.612 0.000
M11.00 Hydroxyapatite deposition disease (Multiple sites)
0.387 0.612 0.000
M11.19 Familial chondrocalcinosis (Site unspecified)
0.387 0.612 0.000
M11.18 Familial chondrocalcinosis (Other)
0.387 0.612 0.000
M11.17 Familial chondrocalcinosis (Ankle and foot)
0.387 0.612 0.000
M11.16 Familial chondrocalcinosis (Lower leg)
0.387 0.612 0.000
M11.15 Familial chondrocalcinosis (Pelvic region and thigh)
0.387 0.612 0.000
M11.14 Familial chondrocalcinosis (Hand)
0.387 0.612 0.000
M11.13 Familial chondrocalcinosis (Forearm)
0.387 0.612 0.000
M11.12 Familial chondrocalcinosis (Upper arm)
0.387 0.612 0.000
M11.11 Familial chondrocalcinosis (Shoulder region)
0.387 0.612 0.000
M11.10 Familial chondrocalcinosis (Multiple sites)
0.387 0.612 0.000
M11.89 Other specified crystal arthropathies (Site unspecified)
0.383 0.616 0.000
M11.88 Other specified crystal arthropathies (Other)
0.383 0.616 0.000
M11.87 Other specified crystal arthropathies (Ankle and foot)
0.383 0.616 0.000
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)
0.383 0.616 0.000
M11.84 Other specified crystal arthropathies (Hand)
0.383 0.616 0.000
M11.83 Other specified crystal arthropathies (Forearm)
0.383 0.616 0.000
M11.82 Other specified crystal arthropathies (Upper arm)
0.383 0.616 0.000
M11.81 Other specified crystal arthropathies (Shoulder region)
0.383 0.616 0.000
M11.80 Other specified crystal arthropathies (Multiple sites)
0.383 0.616 0.000
M11.86 Other specified crystal arthropathies (Lower leg)
0.378 0.622 0.000
T50.8 Diagnostic agents
0.000 0.622 0.377
M10.09 Idiopathic gout (Site unspecified)
0.374 0.626 0.000
M10.19 Lead-induced gout (Site unspecified)
0.373 0.627 0.000
M10.18 Lead-induced gout (Other)
0.373 0.627 0.000
M10.17 Lead-induced gout (Ankle and foot)
0.373 0.627 0.000
M10.16 Lead-induced gout (Lower leg)
0.373 0.627 0.000
M10.15 Lead-induced gout (Pelvic region and thigh)
0.373 0.627 0.000
M10.14 Lead-induced gout (Hand)
0.373 0.627 0.000
M10.13 Lead-induced gout (Forearm)
0.373 0.627 0.000
M10.12 Lead-induced gout (Upper arm)
0.373 0.627 0.000
M10.11 Lead-induced gout (Shoulder region)
0.373 0.627 0.000
M10.10 Lead-induced gout (Multiple sites)
0.373 0.627 0.000
M10.29 Drug-induced gout (Site unspecified)
0.373 0.627 0.000
M10.28 Drug-induced gout (Other)
0.373 0.627 0.000
M10.27 Drug-induced gout (Ankle and foot)
0.373 0.627 0.000
M10.26 Drug-induced gout (Lower leg)
0.373 0.627 0.000
M10.25 Drug-induced gout (Pelvic region and thigh)
0.373 0.627 0.000
M10.24 Drug-induced gout (Hand)
0.373 0.627 0.000
M10.23 Drug-induced gout (Forearm)
0.373 0.627 0.000
M10.22 Drug-induced gout (Upper arm)
0.373 0.627 0.000
M10.21 Drug-induced gout (Shoulder region)
0.373 0.627 0.000
M10.20 Drug-induced gout (Multiple sites)
0.373 0.627 0.000
M10.39 Gout due to impairment of renal function (Site unspecified)
0.373 0.627 0.000
M10.38 Gout due to impairment of renal function (Other)
0.373 0.627 0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.373 0.627 0.000
M10.36 Gout due to impairment of renal function (Lower leg)
0.373 0.627 0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.373 0.627 0.000
M10.34 Gout due to impairment of renal function (Hand)
0.373 0.627 0.000
M10.33 Gout due to impairment of renal function (Forearm)
0.373 0.627 0.000
M10.32 Gout due to impairment of renal function (Upper arm)
0.373 0.627 0.000
M10.31 Gout due to impairment of renal function (Shoulder region)
0.373 0.627 0.000
M10.30 Gout due to impairment of renal function (Multiple sites)
0.373 0.627 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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