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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2284553
log Bayes Factor = <0.0001
Chromosome 21   position 34,776,695  (GRCh37) Explore rs2284553 on Ensembl!
Variant rs2284553 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
F10.2 Dependence syndrome
0.000 0.937 0.063
F10.3 Withdrawal state
0.000 0.938 0.062
F10 Mental and behavioural disorders due to use of alcohol
0.000 0.939 0.061
F10.4 Withdrawal state with delirium
0.000 0.944 0.056
F10.5 Psychotic disorder
0.000 0.945 0.055
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.952 0.048
F10.6 Amnesic syndrome
0.000 0.953 0.047
F10.9 Unspecified mental and behavioural disorder
0.000 0.956 0.044
F10.8 Other mental and behavioural disorders
0.000 0.960 0.040
F10.7 Residual and late-onset psychotic disorder
0.000 0.960 0.040
F10.0 Acute intoxication
0.000 0.961 0.039
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.971 0.029
R29.6 Tendency to fall, not elsewhere classified
0.000 0.973 0.027
E83.1 Disorders of iron metabolism
0.000 0.978 0.022
R29.0 Tetany
0.000 0.979 0.021
R29.4 Clicking hip
0.000 0.979 0.021
R29.3 Abnormal posture
0.000 0.979 0.021
H26.8 Other specified cataract
0.000 0.979 0.021
R29.2 Abnormal reflex
0.000 0.980 0.019
R29.1 Meningismus
0.000 0.981 0.019
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.987 0.013
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.000 0.989 0.011
H21.8 Other specified disorders of iris and ciliary body
0.010 0.990 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.000 0.991 0.009
M13.00 Polyarthritis, unspecified (Multiple sites)
0.009 0.991 0.000
H21 Other disorders of iris and ciliary body
0.009 0.991 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.000 0.992 0.008
F18 Mental and behavioural disorders due to use of volatile solvents
0.000 0.992 0.008
F16 Mental and behavioural disorders due to use of hallucinogens
0.000 0.992 0.008
H21.9 Disorder of iris and ciliary body, unspecified
0.008 0.992 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.000 0.992 0.008
F13.2 Dependence syndrome
0.000 0.993 0.007
H21.5 Other adhesions and disruptions of iris and ciliary body
0.007 0.993 0.000
M13.0 Polyarthritis, unspecified
0.007 0.993 0.000
F11 Mental and behavioural disorders due to use of opioids
0.000 0.993 0.007
F13.9 Unspecified mental and behavioural disorder
0.000 0.993 0.006
F13.8 Other mental and behavioural disorders
0.000 0.993 0.006
F13.7 Residual and late-onset psychotic disorder
0.000 0.993 0.006
F13.6 Amnesic syndrome
0.000 0.993 0.006
F13.5 Psychotic disorder
0.000 0.993 0.006
F13.4 Withdrawal state with delirium
0.000 0.993 0.006
F13.3 Withdrawal state
0.000 0.993 0.006
F13.1 Harmful use
0.000 0.993 0.006
F13.0 Acute intoxication
0.000 0.993 0.006
F17 Mental and behavioural disorders due to use of tobacco
0.000 0.993 0.007
H21.4 Pupillary membranes
0.006 0.993 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.006 0.994 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.006 0.994 0.000
H21.2 Degeneration of iris and ciliary body
0.006 0.994 0.000
F15.1 Harmful use
0.000 0.994 0.006
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.000 0.994 0.006
H21.0 Hyphaema
0.006 0.994 0.000
F17.2 Dependence syndrome
0.000 0.994 0.006
M13.09 Polyarthritis, unspecified (Site unspecified)
0.006 0.994 0.000
F15.9 Unspecified mental and behavioural disorder
0.000 0.994 0.006
F15.8 Other mental and behavioural disorders
0.000 0.994 0.006
F15.7 Residual and late-onset psychotic disorder
0.000 0.994 0.006
F15.6 Amnesic syndrome
0.000 0.994 0.006
F15.5 Psychotic disorder
0.000 0.994 0.006
F15.4 Withdrawal state with delirium
0.000 0.994 0.006
F15.3 Withdrawal state
0.000 0.994 0.006
F15.2 Dependence syndrome
0.000 0.994 0.006
F15.0 Acute intoxication
0.000 0.994 0.006
F12 Mental and behavioural disorders due to use of cannabinoids
0.000 0.994 0.006
F16.9 Unspecified mental and behavioural disorder
0.000 0.994 0.006
F16.8 Other mental and behavioural disorders
0.000 0.994 0.006
F16.7 Residual and late-onset psychotic disorder
0.000 0.994 0.006
F16.6 Amnesic syndrome
0.000 0.994 0.006
F16.5 Psychotic disorder
0.000 0.994 0.006
F16.4 Withdrawal state with delirium
0.000 0.994 0.006
F16.3 Withdrawal state
0.000 0.994 0.006
F16.2 Dependence syndrome
0.000 0.994 0.006
F16.1 Harmful use
0.000 0.994 0.006
F16.0 Acute intoxication
0.000 0.994 0.006
F18.9 Unspecified mental and behavioural disorder
0.000 0.994 0.006
F18.8 Other mental and behavioural disorders
0.000 0.994 0.006
F18.7 Residual and late-onset psychotic disorder
0.000 0.994 0.006
F18.6 Amnesic syndrome
0.000 0.994 0.006
F18.5 Psychotic disorder
0.000 0.994 0.006
F18.4 Withdrawal state with delirium
0.000 0.994 0.006
F18.3 Withdrawal state
0.000 0.994 0.006
F18.2 Dependence syndrome
0.000 0.994 0.006
F18.1 Harmful use
0.000 0.994 0.006
F18.0 Acute intoxication
0.000 0.994 0.006
F14.9 Unspecified mental and behavioural disorder
0.000 0.994 0.006
F14.8 Other mental and behavioural disorders
0.000 0.994 0.006
F14.7 Residual and late-onset psychotic disorder
0.000 0.994 0.006
F14.6 Amnesic syndrome
0.000 0.994 0.006
F14.5 Psychotic disorder
0.000 0.994 0.006
F14.4 Withdrawal state with delirium
0.000 0.994 0.006
F14.3 Withdrawal state
0.000 0.994 0.006
F14.2 Dependence syndrome
0.000 0.994 0.006
F14.0 Acute intoxication
0.000 0.994 0.006
K55.2 Angiodysplasia of colon
0.006 0.994 0.000
F14.1 Harmful use
0.000 0.994 0.005
R22.2 Localised swelling, mass and lump, trunk
0.006 0.994 0.000
M13.06 Polyarthritis, unspecified (Lower leg)
0.005 0.995 0.000
M13.04 Polyarthritis, unspecified (Hand)
0.005 0.995 0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)
0.000 0.995 0.005
C83.3 Large cell (diffuse)
0.005 0.995 0.000
E05.9 Thyrotoxicosis, unspecified
0.005 0.995 0.000
F17.0 Acute intoxication
0.000 0.995 0.005
C83 Diffuse non-Hodgkin's lymphoma
0.005 0.995 0.000
F11.1 Harmful use
0.000 0.995 0.005
H18.5 Hereditary corneal dystrophies
0.005 0.995 0.000
M13.08 Polyarthritis, unspecified (Other)
0.005 0.995 0.000
M13.07 Polyarthritis, unspecified (Ankle and foot)
0.005 0.995 0.000
M13.05 Polyarthritis, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
M13.03 Polyarthritis, unspecified (Forearm)
0.005 0.995 0.000
M13.02 Polyarthritis, unspecified (Upper arm)
0.005 0.995 0.000
M13.01 Polyarthritis, unspecified (Shoulder region)
0.005 0.995 0.000
F11.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F11.8 Other mental and behavioural disorders
0.000 0.995 0.005
F11.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F11.6 Amnesic syndrome
0.000 0.995 0.005
F11.5 Psychotic disorder
0.000 0.995 0.005
F11.4 Withdrawal state with delirium
0.000 0.995 0.005
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.005 0.995 0.000
F17.8 Other mental and behavioural disorders
0.000 0.995 0.005
F17.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F17.6 Amnesic syndrome
0.000 0.995 0.005
F17.5 Psychotic disorder
0.000 0.995 0.005
F17.4 Withdrawal state with delirium
0.000 0.995 0.005
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.005 0.995 0.000
S82.00 Fracture of patella (closed)
0.005 0.995 0.000
F17.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.005 0.995 0.000
F19.9 Unspecified mental and behavioural disorder
0.000 0.995 0.005
F19.8 Other mental and behavioural disorders
0.000 0.995 0.005
F19.7 Residual and late-onset psychotic disorder
0.000 0.995 0.005
F19.6 Amnesic syndrome
0.000 0.995 0.005
F19.5 Psychotic disorder
0.000 0.995 0.005
F19.4 Withdrawal state with delirium
0.000 0.995 0.005
F19.3 Withdrawal state
0.000 0.995 0.005
F19.0 Acute intoxication
0.000 0.995 0.005
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.005 0.995 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.005 0.995 0.000
F11.0 Acute intoxication
0.000 0.995 0.004
M00.9 Pyogenic arthritis, unspecified
0.000 0.995 0.005
C83.1 Small cleaved cell (diffuse)
0.005 0.995 0.000
F11.3 Withdrawal state
0.000 0.995 0.004
N36.0 Urethral fistula
0.000 0.995 0.005
F12.9 Unspecified mental and behavioural disorder
0.000 0.995 0.004
F12.8 Other mental and behavioural disorders
0.000 0.995 0.004
F12.7 Residual and late-onset psychotic disorder
0.000 0.995 0.004
F12.6 Amnesic syndrome
0.000 0.995 0.004
F12.4 Withdrawal state with delirium
0.000 0.995 0.004
F12.3 Withdrawal state
0.000 0.995 0.004
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.004 0.995 0.000
C83.0 Small cell (diffuse)
0.004 0.996 0.000
F12.5 Psychotic disorder
0.000 0.996 0.004
F17.3 Withdrawal state
0.000 0.996 0.004
J30.3 Other allergic rhinitis
0.000 0.996 0.004
M00.91 Pyogenic arthritis, unspecified (Shoulder region)
0.000 0.996 0.004
F19.2 Dependence syndrome
0.000 0.996 0.004
F12.2 Dependence syndrome
0.000 0.996 0.004
F11.2 Dependence syndrome
0.000 0.996 0.004
H15 Disorders of sclera
0.004 0.996 0.000
C83.2 Mixed small and large cell (diffuse)
0.004 0.996 0.000
M00.94 Pyogenic arthritis, unspecified (Hand)
0.000 0.996 0.004
R22.0 Localised swelling, mass and lump, head
0.004 0.996 0.000
C83.7 Burkitt's tumour
0.004 0.996 0.000
F12.1 Harmful use
0.000 0.996 0.004
H18 Other disorders of cornea
0.004 0.996 0.000
F12.0 Acute intoxication
0.000 0.996 0.004
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.004 0.996 0.000
C83.6 Undifferentiated (diffuse)
0.004 0.996 0.000
C83.5 Lymphoblastic (diffuse)
0.004 0.996 0.000
C83.4 Immunoblastic (diffuse)
0.004 0.996 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.004 0.996 0.000
M00.93 Pyogenic arthritis, unspecified (Forearm)
0.000 0.996 0.004
H04.9 Disorder of lachrymal system, unspecified
0.004 0.996 0.000
H15.0 Scleritis
0.004 0.996 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.004 0.996 0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.004 0.996 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.004 0.996 0.000
H17 Corneal scars and opacities
0.004 0.996 0.000
F19.1 Harmful use
0.000 0.996 0.003
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.004 0.996 0.000
H20.9 Iridocyclitis, unspecified
0.004 0.996 0.000
H18.1 Bullous keratopathy
0.004 0.996 0.000
S72.40 Fracture of lower end of femur (closed)
0.004 0.996 0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)
0.000 0.996 0.004
M00.92 Pyogenic arthritis, unspecified (Upper arm)
0.000 0.996 0.004
M00.98 Pyogenic arthritis, unspecified (Other)
0.000 0.996 0.004
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.003 0.996 0.000
H18.3 Changes in corneal membranes
0.003 0.996 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.000 0.996 0.004
H17.8 Other corneal scars and opacities
0.003 0.996 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.000 0.996 0.004
H20 Iridocyclitis
0.003 0.996 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.003 0.997 0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)
0.000 0.997 0.003
M00.90 Pyogenic arthritis, unspecified (Multiple sites)
0.000 0.997 0.003
O63.9 Long labour, unspecified
0.003 0.997 0.000
H18.7 Other corneal deformities
0.003 0.997 0.000
H15.1 Episcleritis
0.003 0.997 0.000
H15.9 Disorder of sclera, unspecified
0.003 0.997 0.000
K86.1 Other chronic pancreatitis
0.003 0.997 0.000
R22.1 Localised swelling, mass and lump, neck
0.003 0.997 0.000
H18.2 Other corneal oedema
0.003 0.997 0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot
0.000 0.997 0.003
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.003 0.997 0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)
0.000 0.997 0.003
H15.8 Other disorders of sclera
0.003 0.997 0.000
H18.0 Corneal pigmentations and deposits
0.003 0.997 0.000
R22.7 Localised swelling, mass and lump, multiple sites
0.003 0.997 0.000
K35 Acute appendicitis
0.000 0.997 0.003
V18.0 Driver injured in nontraffic accident
0.003 0.997 0.000
H17.1 Other central corneal opacity
0.003 0.997 0.000
H17.0 Adherent leukoma
0.003 0.997 0.000
N70.1 Chronic salpingitis and oophoritis
0.000 0.997 0.003
M25.76 Osteophyte (Lower leg)
0.003 0.997 0.000
M25.74 Osteophyte (Hand)
0.003 0.997 0.000
S82.0 Fracture of patella
0.003 0.997 0.000
K86.8 Other specified diseases of pancreas
0.003 0.997 0.000
M00 Pyogenic arthritis
0.000 0.997 0.003
Z36.8 Other antenatal screening
0.003 0.997 0.000
H20.2 Lens-induced iridocyclitis
0.003 0.997 0.000
Z36.2 Other antenatal screening based on amniocentesis
0.003 0.997 0.000
Z36 Antenatal screening
0.003 0.997 0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.002 0.997 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.002 0.997 0.000
H18.9 Disorder of cornea, unspecified
0.003 0.997 0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)
0.003 0.997 0.000
M25.78 Osteophyte (Other)
0.003 0.997 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.003 0.997 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.003 0.997 0.000
M31.3 Wegener's granulomatosis
0.003 0.997 0.000
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.997 0.002
S72.4 Fracture of lower end of femur
0.002 0.997 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.000 0.997 0.003
M00.0 Staphylococcal arthritis and polyarthritis
0.000 0.998 0.002
H16 Keratitis
0.002 0.998 0.000
H18.8 Other specified disorders of cornea
0.002 0.998 0.000
H20.8 Other iridocyclitis
0.002 0.998 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.002 0.998 0.000
S82.01 Fracture of patella (open)
0.002 0.998 0.000
S72.41 Fracture of lower end of femur (open)
0.002 0.998 0.000
H16.9 Keratitis, unspecified
0.002 0.998 0.000
H17.9 Corneal scar and opacity, unspecified
0.002 0.998 0.000
M00.2 Other streptococcal arthritis and polyarthritis
0.000 0.998 0.002
M00.1 Pneumococcal arthritis and polyarthritis
0.000 0.998 0.002
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.998 0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)
0.000 0.998 0.002
R23.3 Spontaneous ecchymoses
0.000 0.998 0.002
O90.8 Other complications of the puerperium, not elsewhere classified
0.002 0.998 0.000
S90.8 Other superficial injuries of ankle and foot
0.000 0.998 0.002
Z36.0 Antenatal screening for chromosomal anomalies
0.002 0.998 0.000
F10.1 Harmful use
0.000 0.998 0.002
M00.8 Arthritis and polyarthritis due to other specified bacterial agents
0.000 0.998 0.002
Z36.5 Antenatal screening for isoimmunisation
0.002 0.998 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.002 0.998 0.000
S12.70 Multiple fractures of cervical spine (closed)
0.002 0.998 0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.002 0.998 0.000
M00.06 Staphylococcal arthritis and polyarthritis (Lower leg)
0.000 0.998 0.002
Z36.1 Antenatal screening for raised alphafetoprotein level
0.002 0.998 0.000
E07.8 Other specified disorders of thyroid
0.002 0.998 0.000
K86 Other diseases of pancreas
0.002 0.998 0.000
M25.7 Osteophyte
0.002 0.998 0.000
M00.09 Staphylococcal arthritis and polyarthritis (Site unspecified)
0.000 0.998 0.002
M00.08 Staphylococcal arthritis and polyarthritis (Other)
0.000 0.998 0.002
M00.07 Staphylococcal arthritis and polyarthritis (Ankle and foot)
0.000 0.998 0.002
M00.05 Staphylococcal arthritis and polyarthritis (Pelvic region and thigh)
0.000 0.998 0.002
M00.04 Staphylococcal arthritis and polyarthritis (Hand)
0.000 0.998 0.002
M00.03 Staphylococcal arthritis and polyarthritis (Forearm)
0.000 0.998 0.002
M00.02 Staphylococcal arthritis and polyarthritis (Upper arm)
0.000 0.998 0.002
M00.01 Staphylococcal arthritis and polyarthritis (Shoulder region)
0.000 0.998 0.002
M00.00 Staphylococcal arthritis and polyarthritis (Multiple sites)
0.000 0.998 0.002
S82.40 Fracture of fibula alone (closed)
0.002 0.998 0.000
M75.5 Bursitis of shoulder
0.002 0.998 0.000
M75.0 Adhesive capsulitis of shoulder
0.002 0.998 0.000
R22.3 Localised swelling, mass and lump, upper limb
0.002 0.998 0.000
H16.0 Corneal ulcer
0.002 0.998 0.000
H20.0 Acute and subacute iridocyclitis
0.002 0.998 0.000
K86.3 Pseudocyst of pancreas
0.002 0.998 0.000
H20.1 Chronic iridocyclitis
0.001 0.998 0.001
K35.3 Acute appendicitis with localized peritonitis
0.000 0.998 0.002
S90 Superficial injury of ankle and foot
0.000 0.998 0.002
M00.19 Pneumococcal arthritis and polyarthritis (Site unspecified)
0.000 0.998 0.002
M00.18 Pneumococcal arthritis and polyarthritis (Other)
0.000 0.998 0.002
M00.17 Pneumococcal arthritis and polyarthritis (Ankle and foot)
0.000 0.998 0.002
M00.16 Pneumococcal arthritis and polyarthritis (Lower leg)
0.000 0.998 0.002
M00.15 Pneumococcal arthritis and polyarthritis (Pelvic region and thigh)
0.000 0.998 0.002
M00.14 Pneumococcal arthritis and polyarthritis (Hand)
0.000 0.998 0.002
M00.13 Pneumococcal arthritis and polyarthritis (Forearm)
0.000 0.998 0.002
M00.12 Pneumococcal arthritis and polyarthritis (Upper arm)
0.000 0.998 0.002
M00.11 Pneumococcal arthritis and polyarthritis (Shoulder region)
0.000 0.998 0.002
M00.10 Pneumococcal arthritis and polyarthritis (Multiple sites)
0.000 0.998 0.002
M00.29 Other streptococcal arthritis and polyarthritis (Site unspecified)
0.000 0.998 0.002
M00.28 Other streptococcal arthritis and polyarthritis (Other)
0.000 0.998 0.002
M00.27 Other streptococcal arthritis and polyarthritis (Ankle and foot)
0.000 0.998 0.002
M00.26 Other streptococcal arthritis and polyarthritis (Lower leg)
0.000 0.998 0.002
M00.25 Other streptococcal arthritis and polyarthritis (Pelvic region and thigh)
0.000 0.998 0.002
M00.24 Other streptococcal arthritis and polyarthritis (Hand)
0.000 0.998 0.002
M00.23 Other streptococcal arthritis and polyarthritis (Forearm)
0.000 0.998 0.002
M00.22 Other streptococcal arthritis and polyarthritis (Upper arm)
0.000 0.998 0.002
M00.21 Other streptococcal arthritis and polyarthritis (Shoulder region)
0.000 0.998 0.002
M00.20 Other streptococcal arthritis and polyarthritis (Multiple sites)
0.000 0.998 0.002
I72.3 Aneurysm of iliac artery
0.002 0.998 0.000
S82.50 Fracture of medial malleolus (closed)
0.002 0.998 0.000
O90.9 Complication of the puerperium, unspecified
0.002 0.998 0.000
M00.89 Arthritis and polyarthritis due to other specified bacterial agents (Site unspecified)
0.000 0.998 0.002
M00.88 Arthritis and polyarthritis due to other specified bacterial agents (Other)
0.000 0.998 0.002
M00.87 Arthritis and polyarthritis due to other specified bacterial agents (Ankle and foot)
0.000 0.998 0.002
M00.85 Arthritis and polyarthritis due to other specified bacterial agents (Pelvic region and thigh)
0.000 0.998 0.002
M00.84 Arthritis and polyarthritis due to other specified bacterial agents (Hand)
0.000 0.998 0.002
M00.83 Arthritis and polyarthritis due to other specified bacterial agents (Forearm)
0.000 0.998 0.002
M00.82 Arthritis and polyarthritis due to other specified bacterial agents (Upper arm)
0.000 0.998 0.002
M00.81 Arthritis and polyarthritis due to other specified bacterial agents (Shoulder region)
0.000 0.998 0.002
M00.80 Arthritis and polyarthritis due to other specified bacterial agents (Multiple sites)
0.000 0.998 0.002
U80.1 Methicillin resistant agent
0.000 0.998 0.002
H18.6 Keratoconus
0.001 0.998 0.001
M72.2 Plantar fascial fibromatosis
0.000 0.998 0.002
S62.8 Fracture of other and unspecified parts of wrist and hand
0.002 0.998 0.000
S90.0 Contusion of ankle
0.000 0.998 0.002
D04.6 Skin of upper limb, including shoulder
0.000 0.998 0.002
H16.8 Other keratitis
0.002 0.998 0.000
H16.4 Corneal neovascularisation
0.002 0.998 0.000
H16.3 Interstitial and deep keratitis
0.002 0.998 0.000
M00.86 Arthritis and polyarthritis due to other specified bacterial agents (Lower leg)
0.000 0.998 0.002
S82.21 Fracture of shaft of tibia (open)
0.002 0.998 0.000
M50.2 Other cervical disk displacement
0.002 0.998 0.000
D33.3 Cranial nerves
0.000 0.998 0.002
K86.0 Alcohol-induced chronic pancreatitis
0.002 0.998 0.000
O90 Complications of the puerperium, not elsewhere classified
0.002 0.998 0.000
O90.2 Haematoma of obstetric wound
0.002 0.998 0.000
S82.4 Fracture of fibula alone
0.002 0.998 0.000
D28.0 Vulva
0.000 0.998 0.002
N49.2 Inflammatory disorders of scrotum
0.000 0.998 0.002
M25.70 Osteophyte (Multiple sites)
0.002 0.998 0.000
H18.4 Corneal degeneration
0.001 0.998 0.000
I86.1 Scrotal varices
0.000 0.998 0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.002 0.998 0.000
M54.57 Low back pain (Lumbosacral region)
0.002 0.998 0.000
F81.9 Developmental disorder of scholastic skills, unspecified
0.002 0.998 0.000
S82.2 Fracture of shaft of tibia
0.002 0.998 0.000
T79.6 Traumatic ischaemia of muscle
0.000 0.998 0.002
Y85.0 Sequelae of motor-vehicle accident
0.002 0.998 0.000
M25.79 Osteophyte (Site unspecified)
0.002 0.998 0.000
M25.73 Osteophyte (Forearm)
0.002 0.998 0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)
0.002 0.998 0.000
H16.1 Other superficial keratitis without conjunctivitis
0.001 0.998 0.000
M72.29 Plantar fascial fibromatosis-Site unspec
0.000 0.998 0.002
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.002 0.998 0.000
S90.7 Multiple superficial injuries of ankle and foot
0.000 0.998 0.002
S90.2 Contusion of toe(s) with damage to nail
0.000 0.998 0.002
S72.30 Fracture of shaft of femur (closed)
0.002 0.998 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.002 0.998 0.000
J93.1 Other spontaneous pneumothorax
0.000 0.998 0.002
S82.10 Fracture of upper end of tibia (closed)
0.002 0.998 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.002 0.998 0.000
H16.2 Keratoconjunctivitis
0.001 0.998 0.001
O23.4 Unspecified infection of urinary tract in pregnancy
0.002 0.998 0.000
E07 Other disorders of thyroid
0.002 0.998 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.000 0.998 0.002
M72.28 Plantar fascial fibromatosis-Other
0.000 0.998 0.001
M72.26 Plantar fascial fibromatosis-Lower Leg
0.000 0.998 0.001
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh
0.000 0.998 0.001
M72.24 Plantar fascial fibromatosis-Hand
0.000 0.998 0.001
M72.23 Plantar fascial fibromatosis-Forearm
0.000 0.998 0.001
M72.22 Plantar fascial fibromatosis-Upper arm
0.000 0.998 0.001
M72.21 Plantar fascial fibromatosis-Shldr region
0.000 0.998 0.001
M72.20 Plantar fascial fibromatosis-Mult sites
0.000 0.998 0.001
I33.0 Acute and subacute infective endocarditis
0.002 0.998 0.000
S82.5 Fracture of medial malleolus
0.002 0.998 0.000
S82.1 Fracture of upper end of tibia
0.002 0.998 0.000
S90.3 Contusion of other and unspecified parts of foot
0.000 0.998 0.001
E78.4 Other hyperlipidaemia
0.002 0.998 0.000
S12.7 Multiple fractures of cervical spine
0.002 0.998 0.000
T93.2 Sequelae of other fractures of lower limb
0.002 0.998 0.000
S82 Fracture of lower leg, including ankle
0.002 0.998 0.000
S82.41 Fracture of fibula alone (open)
0.001 0.998 0.000
O90.5 Postpartum thyroiditis
0.001 0.998 0.000
O90.4 Postpartum acute renal failure
0.001 0.998 0.000
O90.3 Cardiomyopathy in the puerperium
0.001 0.998 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.001 0.998 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.998 0.002
S90.1 Contusion of toe(s) without damage to nail
0.000 0.998 0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)
0.002 0.998 0.000
N81.5 Vaginal enterocele
0.002 0.998 0.000
S02.00 Fracture of vault of skull (closed)
0.001 0.998 0.000
C92.1 Chronic myeloid leukaemia
0.000 0.998 0.001
O75.0 Maternal distress during labour and delivery
0.000 0.998 0.002
S62.0 Fracture of navicular [scaphoid] bone of hand
0.001 0.998 0.001
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.001 0.998 0.000
S82.20 Fracture of shaft of tibia (closed)
0.001 0.998 0.000
C82.0 Small cleaved cell, follicular
0.001 0.998 0.000
O90.0 Disruption of Caesarean section wound
0.001 0.998 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.001 0.999 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.001 0.999 0.000
E07.9 Disorder of thyroid, unspecified
0.001 0.999 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.001 0.999 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.001 0.999 0.000
S12.20 Fracture of other specified cervical vertebra (closed)
0.001 0.999 0.000
E07.1 Dyshormogenetic goitre
0.001 0.999 0.000
E07.0 Hypersecretion of calcitonin
0.001 0.999 0.000
S82.11 Fracture of upper end of tibia (open)
0.001 0.999 0.000
E06.3 Autoimmune thyroiditis
0.001 0.999 0.000
V18.3 Person injured while boarding or alighting
0.001 0.999 0.000
S12.71 Multiple fractures of cervical spine (open)
0.001 0.999 0.000
S62.50 Fracture of thumb (closed)
0.001 0.999 0.000
E03.9 Hypothyroidism, unspecified
0.001 0.999 0.000
N84.2 Polyp of vagina
0.001 0.999 0.000
O90.1 Disruption of perineal obstetric wound
0.001 0.999 0.000
Z36.9 Antenatal screening, unspecified
0.001 0.999 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.999 0.001
M25.71 Osteophyte (Shoulder region)
0.001 0.999 0.000
R02 Gangrene, not elsewhere classified
0.000 0.999 0.001
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.001 0.999 0.000
M79.60 Pain in limb (Multiple sites)
0.000 0.999 0.001
E87.2 Acidosis
0.000 0.999 0.001
V18.1 Passenger injured in nontraffic accident
0.001 0.999 0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)
0.001 0.999 0.001
J38.5 Laryngeal spasm
0.001 0.999 0.000
U80 Agent resistant to penicillin and related antibiotics
0.000 0.999 0.001
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.999 0.001
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.001 0.999 0.000
F80.1 Expressive language disorder
0.001 0.999 0.000
S72.3 Fracture of shaft of femur
0.001 0.999 0.000
V17.4 Driver injured in traffic accident
0.001 0.999 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.001 0.999 0.000
M25.84 Other specified joint disorders (Hand)
0.001 0.999 0.000
E05.5 Thyroid crisis or storm
0.001 0.999 0.000
E05.4 Thyrotoxicosis factitia
0.001 0.999 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.001 0.999 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.001 0.999 0.000
V18.9 Unspecified pedal cyclist injured in traffic accident
0.001 0.999 0.000
V18.4 Driver injured in traffic accident
0.001 0.999 0.000
C48.1 Specified parts of peritoneum
0.000 0.999 0.001
N60.8 Other benign mammary dysplasias
0.000 0.999 0.001
S99.9 Unspecified injury of ankle and foot
0.001 0.999 0.000
E06 Thyroiditis
0.001 0.999 0.000
M10.90 Gout, unspecified (Multiple sites)
0.000 0.999 0.001
J38.4 Oedema of larynx
0.000 0.999 0.001
M25.06 Haemarthrosis (Lower leg)
0.001 0.999 0.000
S72.31 Fracture of shaft of femur (open)
0.001 0.999 0.000
S82.9 Fracture of lower leg, part unspecified
0.001 0.999 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.001 0.999 0.000
E06.5 Other chronic thyroiditis
0.001 0.999 0.000
H10.9 Conjunctivitis, unspecified
0.000 0.999 0.001
S12.2 Fracture of other specified cervical vertebra
0.001 0.999 0.000
S82.7 Multiple fractures of lower leg
0.001 0.999 0.000
M25.77 Osteophyte (Ankle and foot)
0.001 0.999 0.000
F80.2 Receptive language disorder
0.001 0.999 0.000
Q85.8 Other phakomatoses, not elsewhere classified
0.001 0.999 0.000
M25.72 Osteophyte (Upper arm)
0.001 0.999 0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity
0.001 0.999 0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity
0.001 0.999 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.001 0.999 0.000
E05.8 Other thyrotoxicosis
0.001 0.999 0.000
E06.1 Subacute thyroiditis
0.001 0.999 0.000
H50.4 Other and unspecified heterotropia
0.001 0.999 0.000
Y85.9 Sequelae of other and unspecified transport accidents
0.001 0.999 0.000
Q85 Phakomatoses, not elsewhere classified
0.001 0.999 0.000
S82.51 Fracture of medial malleolus (open)
0.001 0.999 0.000
E06.4 Drug-induced thyroiditis
0.001 0.999 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.001 0.999 0.000
E06.0 Acute thyroiditis
0.001 0.999 0.000
I84.5 External haemorrhoids without complication
0.000 0.999 0.001
S14.3 Injury of brachial plexus
0.001 0.999 0.000
S14.1 Other and unspecified injuries of cervical spinal cord
0.001 0.999 0.000
S62.5 Fracture of thumb
0.001 0.999 0.000
F81 Specific developmental disorders of scholastic skills
0.001 0.999 0.000
S62.40 Multiple fractures of metacarpal bones (closed)
0.001 0.999 0.000
O45.9 Premature separation of placenta, unspecified
0.001 0.999 0.000
Q85.1 Tuberous sclerosis
0.001 0.999 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.000 0.999 0.001
M00-M03 Infectious arthropathies
0.000 0.999 0.001
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.001 0.999 0.000
S12.21 Fracture of other specified cervical vertebra (open)
0.001 0.999 0.000
S62.71 Multiple fractures of fingers (open)
0.001 0.999 0.000
S82.71 Multiple fractures of lower leg (open)
0.001 0.999 0.000
U80.0 Penicillin resistant agent
0.000 0.999 0.001
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.001 0.999 0.000
S82.91 Fracture of lower leg, part unspecified (open)
0.001 0.999 0.000
C82.2 Large cell, follicular
0.001 0.999 0.000
E06.9 Thyroiditis, unspecified
0.001 0.999 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.001 0.999 0.000
O14.9 Preeclampsia, unspecified
0.001 0.999 0.000
V18.5 Passenger injured in traffic accident
0.001 0.999 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.999 0.001
M53.82 Other specified dorsopathies (Cervical region)
0.000 0.999 0.001
S42.90 Fracture of shoulder girdle, part unspecified (closed)
0.001 0.999 0.000
F81.8 Other developmental disorders of scholastic skills
0.001 0.999 0.000
F81.3 Mixed disorder of scholastic skills
0.001 0.999 0.000
F81.2 Specific disorder of arithmetical skills
0.001 0.999 0.000
F81.1 Specific spelling disorder
0.001 0.999 0.000
F81.0 Specific reading disorder
0.001 0.999 0.000
K12.2 Cellulitis and abscess of mouth
0.001 0.999 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.000 0.999 0.001
F80 Specific developmental disorders of speech and language
0.001 0.999 0.000
M02.90 Reactive arthropathy, unspecified (Multiple sites)
0.001 0.999 0.000
S12.00 Fracture of first cervical vertebra (closed)
0.000 0.999 0.001
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.999 0.001
K86.9 Disease of pancreas, unspecified
0.001 0.999 0.000
N92.5 Other specified irregular menstruation
0.000 0.999 0.001
S62.4 Multiple fractures of metacarpal bones
0.001 0.999 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.999 0.001
M02 Reactive arthropathies
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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