TreeWAS – Variant ID: rs228614

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L40.0 Psoriasis vulgaris	0.000	0.947	0.053
L40.9 Psoriasis, unspecified	0.000	0.950	0.050
L40 Psoriasis	0.000	0.950	0.050
D86.0 Sarcoidosis of lung	0.000	0.953	0.047
L40.3 Pustulosis palmaris et plantaris	0.000	0.958	0.042
D86 Sarcoidosis	0.000	0.962	0.038
L40.8 Other psoriasis	0.000	0.963	0.037
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.037	0.963	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.964	0.036
L40.2 Acrodermatitis continua	0.000	0.964	0.036
L40.1 Generalised pustular psoriasis	0.000	0.964	0.036
L40.4 Guttate psoriasis	0.000	0.965	0.035
D70 Agranulocytosis	0.000	0.965	0.035
L40.5 Arthropathic psoriasis	0.000	0.969	0.031
D17.9 Benign lipomatous neoplasm, unspecified	0.031	0.969	0.000
D17 Benign lipomatous neoplasm	0.030	0.970	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.030	0.970	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.971	0.029
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.971	0.029
D60-D64 Aplastic and other anaemias	0.000	0.972	0.028
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.972	0.028
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.972	0.028
D63 Anaemia in chronic diseases classified elsewhere	0.000	0.973	0.027
D86.3 Sarcoidosis of skin	0.000	0.973	0.027
D63.8 Anaemia in other chronic diseases classified elsewhere	0.000	0.973	0.027
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.026	0.974	0.000
N50.8 Other specified disorders of male genital organs	0.026	0.974	0.000
D64 Other anaemias	0.000	0.974	0.026
D61 Other aplastic anaemias	0.000	0.976	0.024
D64.9 Anaemia, unspecified	0.000	0.977	0.023
D72 Other disorders of white blood cells	0.000	0.977	0.023
D86.1 Sarcoidosis of lymph nodes	0.000	0.978	0.022
D55-D59 Haemolytic anaemias	0.000	0.978	0.022
D83 Common variable immunodeficiency	0.000	0.978	0.021
D82 Immunodeficiency associated with other major defects	0.000	0.978	0.021
D64.8 Other specified anaemias	0.000	0.979	0.021
D81 Combined immunodeficiencies	0.000	0.979	0.021
D63.0 Anaemia in neoplastic disease	0.000	0.979	0.021
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.021	0.979	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.979	0.021
D74 Methaemoglobinaemia	0.000	0.979	0.020
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.979	0.020
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.979	0.020
D84 Other immunodeficiencies	0.000	0.980	0.020
D63.1 Anaemia in other chronic diseases classified elsewhere	0.000	0.980	0.020
D61.0 Constitutional aplastic anaemia	0.000	0.980	0.019
D86.8 Sarcoidosis of other and combined sites	0.000	0.981	0.019
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.019	0.981	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.981	0.019
D59 Acquired haemolytic anaemia	0.000	0.981	0.019
D64.4 Congenital dyserythropoietic anaemia	0.000	0.981	0.019
D64.3 Other sideroblastic anaemias	0.000	0.981	0.019
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.000	0.981	0.019
D64.1 Secondary sideroblastic anaemia due to disease	0.000	0.981	0.019
D64.0 Hereditary sideroblastic anaemia	0.000	0.981	0.019
S20.2 Contusion of thorax	0.000	0.981	0.019
D80 Immunodeficiency with predominantly antibody defects	0.000	0.982	0.018
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.982	0.018
L40-L45 Papulosquamous disorders	0.000	0.982	0.018
D61.8 Other specified aplastic anaemias	0.000	0.982	0.017
D61.3 Idiopathic aplastic anaemia	0.000	0.982	0.017
D61.2 Aplastic anaemia due to other external agents	0.000	0.982	0.017
D21 Other benign neoplasms of connective and other soft tissue	0.018	0.982	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.000	0.983	0.017
D21.0 Connective and other soft tissue of head, face and neck	0.017	0.983	0.000
D59.1 Other autoimmune haemolytic anaemias	0.000	0.983	0.017
D72.9 Disorder of white blood cells, unspecified	0.000	0.983	0.016
D72.0 Genetic anomalies of leukocytes	0.000	0.983	0.016
D62 Acute posthaemorrhagic anaemia	0.000	0.983	0.017
D58 Other hereditary haemolytic anaemias	0.000	0.984	0.016
D21.2 Connective and other soft tissue of lower limb, including hip	0.016	0.984	0.000
D72.1 Eosinophilia	0.000	0.984	0.016
D57 Sickle-cell disorders	0.000	0.984	0.016
D83.9 Common variable immunodeficiency, unspecified	0.000	0.984	0.016
D55 Anaemia due to enzyme disorders	0.000	0.984	0.016
D82.1 Di George's syndrome	0.000	0.984	0.016
D75 Other diseases of blood and blood-forming organs	0.000	0.984	0.016
D61.1 Drug-induced aplastic anaemia	0.000	0.984	0.016
D83.8 Other common variable immunodeficiencies	0.000	0.984	0.016
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.984	0.016
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.984	0.016
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.984	0.016
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.016	0.984	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.984	0.016
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.984	0.016
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.984	0.016
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.984	0.016
D82.2 Immunodeficiency with short-limbed stature	0.000	0.984	0.016
D82.0 Wiskott-Aldrich syndrome	0.000	0.984	0.016
D81.9 Combined immunodeficiency, unspecified	0.000	0.984	0.015
D81.8 Other combined immunodeficiencies	0.000	0.984	0.015
D81.7 Major histocompatibility complex class II deficiency	0.000	0.984	0.015
D81.6 Major histocompatibility complex class I deficiency	0.000	0.984	0.015
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.984	0.015
D81.4 Nezelof's syndrome	0.000	0.984	0.015
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.984	0.015
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.984	0.015
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.984	0.015
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.984	0.015
D21.9 Connective and other soft tissue, unspecified	0.015	0.985	0.000
D21.5 Connective and other soft tissue of pelvis	0.015	0.985	0.000
D74.9 Methaemoglobinaemia, unspecified	0.000	0.985	0.015
D74.8 Other methaemoglobinaemias	0.000	0.985	0.015
D74.0 Congenital methaemoglobinaemia	0.000	0.985	0.015
D84.1 Defects in the complement system	0.000	0.985	0.015
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.985	0.015
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.985	0.014
D17.7 Benign lipomatous neoplasm of other sites	0.014	0.986	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.986	0.014
D59.8 Other acquired haemolytic anaemias	0.000	0.986	0.014
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.986	0.014
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.986	0.014
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.986	0.014
D59.3 Haemolytic-uraemic syndrome	0.000	0.986	0.014
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.986	0.014
L42 Pityriasis rosea	0.000	0.986	0.014
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.986	0.014
D84.9 Immunodeficiency, unspecified	0.000	0.986	0.014
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.986	0.014
D84.8 Other specified immunodeficiencies	0.000	0.986	0.014
D21.6 Connective and other soft tissue of trunk, unspecified	0.013	0.987	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.987	0.013
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.987	0.013
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.987	0.013
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.987	0.013
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.987	0.013
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.987	0.013
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.987	0.013
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.987	0.013
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.987	0.013
L41 Parapsoriasis	0.000	0.987	0.013
L45 Papulosquamous disorders in diseases classified elsewhere	0.000	0.987	0.013
D23.1 Skin of eyelid, including canthus	0.013	0.987	0.000
D21.4 Connective and other soft tissue of abdomen	0.013	0.987	0.000
D21.3 Connective and other soft tissue of thorax	0.013	0.987	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.987	0.013
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.987	0.013
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.987	0.013
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.987	0.013
D60.8 Other acquired pure red cell aplasias	0.000	0.987	0.012
D60.1 Transient acquired pure red cell aplasia	0.000	0.987	0.012
D60.0 Chronic acquired pure red cell aplasia	0.000	0.987	0.012
D69 Purpura and other haemorrhagic conditions	0.000	0.987	0.013
D56 Thalassaemia	0.000	0.987	0.012
D57.1 Sickle-cell anaemia without crisis	0.000	0.987	0.012
D75.1 Secondary polycythaemia	0.000	0.988	0.012
D69.9 Haemorrhagic condition, unspecified	0.000	0.988	0.012
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.988	0.012
D58.1 Hereditary elliptocytosis	0.000	0.988	0.012
L44 Other papulosquamous disorders	0.000	0.988	0.012
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.988	0.012
D58.2 Other haemoglobinopathies	0.000	0.988	0.012
D69.3 Idiopathic thrombocytopenic purpura	0.000	0.988	0.012
D57.8 Other sickle-cell disorders	0.000	0.988	0.012
D57.2 Double heterozygous sickling disorders	0.000	0.988	0.012
D57.0 Sickle-cell anaemia with crisis	0.000	0.988	0.012
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.988	0.011
D55.8 Other anaemias due to enzyme disorders	0.000	0.988	0.011
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.988	0.011
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.988	0.011
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.988	0.011
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.988	0.011
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.988	0.011
L43 Lichen planus	0.000	0.989	0.011
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.989	0.011
D57.3 Sickle-cell trait	0.000	0.989	0.011
D76.3 Other histiocytosis syndromes	0.000	0.989	0.010
D75.2 Essential thrombocytosis	0.000	0.989	0.011
Z89.5 Acquired absence of leg at or below knee	0.011	0.989	0.000
M62.88 Other specified disorders of muscle (Other)	0.000	0.990	0.010
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.990	0.010
D69.6 Thrombocytopenia, unspecified	0.000	0.990	0.010
Z89 Acquired absence of limb	0.010	0.990	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.990	0.010
D69.1 Qualitative platelet defects	0.000	0.990	0.010
D60.9 Acquired pure red cell aplasia, unspecified	0.001	0.990	0.009
L41.9 Parapsoriasis, unspecified	0.000	0.990	0.009
L41.8 Other parapsoriasis	0.000	0.990	0.009
L41.5 Retiform parapsoriasis	0.000	0.990	0.009
L41.4 Large plaque parapsoriasis	0.000	0.990	0.009
L41.3 Small plaque parapsoriasis	0.000	0.990	0.009
L41.2 Lymphomatoid papulosis	0.000	0.990	0.009
L41.1 Pityriasis lichenoides chronica	0.000	0.990	0.009
L41.0 Pityriasis lichenoides et varioliformis acuta	0.000	0.990	0.009
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.990	0.009
D89.3 Immune reconstitution syndrome	0.000	0.990	0.009
D58.0 Hereditary spherocytosis	0.000	0.991	0.009
D69.8 Other specified haemorrhagic conditions	0.000	0.991	0.009
D75.0 Familial erythrocytosis	0.000	0.991	0.009
D56.9 Thalassaemia, unspecified	0.000	0.991	0.009
D56.8 Other thalassaemias	0.000	0.991	0.009
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.991	0.009
D56.2 Delta-beta thalassaemia	0.000	0.991	0.009
D56.0 Alpha thalassaemia	0.000	0.991	0.009
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.991	0.009
M62.8 Other specified disorders of muscle	0.000	0.991	0.009
D73 Diseases of spleen	0.000	0.991	0.009
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.009	0.991	0.000
L43.8 Other lichen planus	0.000	0.991	0.009
L44.9 Papulosquamous disorder, unspecified	0.000	0.991	0.009
L44.8 Other specified papulosquamous disorders	0.000	0.991	0.009
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]	0.000	0.991	0.009
L44.3 Lichen ruber moniliformis	0.000	0.991	0.009
L44.2 Lichen striatus	0.000	0.991	0.009
L44.1 Lichen nitidus	0.000	0.991	0.009
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.009	0.991	0.000
Z89.4 Acquired absence of foot and ankle	0.009	0.991	0.000
D69.5 Secondary thrombocytopenia	0.000	0.991	0.008
D69.2 Other nonthrombocytopenic purpura	0.000	0.991	0.008
L43.3 Subacute (active) lichen planus	0.000	0.992	0.008
L43.2 Lichenoid drug reaction	0.000	0.992	0.008
L43.1 Bullous lichen planus	0.000	0.992	0.008
L43.0 Hypertrophic lichen planus	0.000	0.992	0.008
Z89.8 Acquired absence of upper and lower limbs [any level]	0.008	0.992	0.000
D56.1 Beta thalassaemia	0.000	0.992	0.008
D69.4 Other primary thrombocytopenia	0.000	0.992	0.008
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.992	0.008
L44.0 Pityriasis rubra pilaris	0.000	0.992	0.008
Z89.9 Acquired absence of limb, unspecified	0.008	0.992	0.000
D66 Hereditary factor VIII deficiency	0.000	0.992	0.008
D67 Hereditary factor IX deficiency	0.000	0.992	0.008
M25.06 Haemarthrosis (Lower leg)	0.008	0.992	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.992	0.008
D56.3 Thalassaemia trait	0.000	0.992	0.007
D89.1 Cryoglobulinaemia	0.000	0.992	0.007
Z89.6 Acquired absence of leg above knee	0.007	0.992	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.007	0.993	0.000
Z89.1 Acquired absence of hand and wrist	0.007	0.993	0.000
Z89.2 Acquired absence of upper limb above wrist	0.007	0.993	0.000
D73.4 Cyst of spleen	0.000	0.993	0.007
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.993	0.007
M62.84 Other specified disorders of muscle (Hand)	0.000	0.993	0.007
D69.0 Allergic purpura	0.000	0.993	0.007
D73.9 Disease of spleen, unspecified	0.000	0.993	0.007
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.993	0.007
D73.3 Abscess of spleen	0.000	0.993	0.007
D73.2 Chronic congestive splenomegaly	0.000	0.993	0.007
D73.1 Hypersplenism	0.000	0.993	0.007
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.993	0.007
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.993	0.007
M62 Other disorders of muscle	0.000	0.993	0.007
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.993	0.007
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.000	0.994	0.006
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.994	0.006
H92.1 Otorrhoea	0.006	0.994	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.994	0.006
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.006	0.994	0.000
D73.5 Infarction of spleen	0.000	0.994	0.006
S20 Superficial injury of thorax	0.000	0.994	0.006
T78.3 Angioneurotic oedema	0.000	0.995	0.005
L43.9 Lichen planus, unspecified	0.000	0.995	0.005
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.000	0.995	0.005
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.000	0.995	0.005
D50-D53 Nutritional anaemias	0.000	0.995	0.005
S20.1 Other and unspecified superficial injuries of breast	0.000	0.995	0.005
M62.9 Disorder of muscle, unspecified	0.000	0.995	0.005
D73.8 Other diseases of spleen	0.000	0.995	0.005
O90.8 Other complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
M62.4 Contracture of muscle	0.000	0.995	0.005
M62.3 Immobility syndrome (paraplegic)	0.000	0.995	0.005
M62.2 Ischaemic infarction of muscle	0.000	0.995	0.005
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.995	0.005
M62.0 Diastasis of muscle	0.000	0.995	0.005
Z29.1 Prophylactic immunotherapy	0.000	0.995	0.005
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.000	0.995	0.005
M62.1 Other rupture of muscle (nontraumatic)	0.000	0.995	0.005
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.000	0.995	0.004
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.000	0.995	0.004
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.000	0.995	0.004
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.000	0.995	0.004
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.995	0.005
M62.6 Muscle strain	0.000	0.995	0.004
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.000	0.995	0.004
T78 Adverse effects, not elsewhere classified	0.000	0.995	0.005
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.000	0.996	0.004
C85.1 B-cell lymphoma, unspecified	0.000	0.996	0.004
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.000	0.996	0.004
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.996	0.004
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.996	0.004
S20.7 Multiple superficial injuries of thorax	0.000	0.996	0.004
S20.3 Other superficial injuries of front wall of thorax	0.000	0.996	0.004
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.996	0.004
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.996	0.004
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.000	0.996	0.004
S20.0 Contusion of breast	0.000	0.996	0.004
M62.98 Disorder of muscle, unspecified (Other)	0.000	0.996	0.004
M62.97 Disorder of muscle, unspecified (Ankle and foot)	0.000	0.996	0.004
M62.96 Disorder of muscle, unspecified (Lower leg)	0.000	0.996	0.004
M62.95 Disorder of muscle, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M62.94 Disorder of muscle, unspecified (Hand)	0.000	0.996	0.004
M62.93 Disorder of muscle, unspecified (Forearm)	0.000	0.996	0.004
M62.92 Disorder of muscle, unspecified (Upper arm)	0.000	0.996	0.004
M62.91 Disorder of muscle, unspecified (Shoulder region)	0.000	0.996	0.004
M62.90 Disorder of muscle, unspecified (Multiple sites)	0.000	0.996	0.004
T78.2 Anaphylactic shock, unspecified	0.000	0.996	0.004
M62.29 Ischaemic infarction of muscle (Site unspecified)	0.000	0.996	0.004
M62.28 Ischaemic infarction of muscle (Other)	0.000	0.996	0.004
M62.27 Ischaemic infarction of muscle (Ankle and foot)	0.000	0.996	0.004
M62.26 Ischaemic infarction of muscle (Lower leg)	0.000	0.996	0.004
M62.25 Ischaemic infarction of muscle (Pelvic region and thigh)	0.000	0.996	0.004
M62.24 Ischaemic infarction of muscle (Hand)	0.000	0.996	0.004
M62.23 Ischaemic infarction of muscle (Forearm)	0.000	0.996	0.004
M62.22 Ischaemic infarction of muscle (Upper arm)	0.000	0.996	0.004
M62.21 Ischaemic infarction of muscle (Shoulder region)	0.000	0.996	0.004
M62.20 Ischaemic infarction of muscle (Multiple sites)	0.000	0.996	0.004
M62.39 Immobility syndrome (paraplegic) (Site unspecified)	0.000	0.996	0.004
M62.38 Immobility syndrome (paraplegic) (Other)	0.000	0.996	0.004
M62.37 Immobility syndrome (paraplegic) (Ankle and foot)	0.000	0.996	0.004
M62.36 Immobility syndrome (paraplegic) (Lower leg)	0.000	0.996	0.004
M62.35 Immobility syndrome (paraplegic) (Pelvic region and thigh)	0.000	0.996	0.004
M62.34 Immobility syndrome (paraplegic) (Hand)	0.000	0.996	0.004
M62.33 Immobility syndrome (paraplegic) (Forearm)	0.000	0.996	0.004
M62.32 Immobility syndrome (paraplegic) (Upper arm)	0.000	0.996	0.004
M62.31 Immobility syndrome (paraplegic) (Shoulder region)	0.000	0.996	0.004
M62.30 Immobility syndrome (paraplegic) (Multiple sites)	0.000	0.996	0.004
M62.49 Contracture of muscle (Site unspecified)	0.000	0.996	0.004
M62.48 Contracture of muscle (Other)	0.000	0.996	0.004
M62.47 Contracture of muscle (Ankle and foot)	0.000	0.996	0.004
M62.46 Contracture of muscle (Lower leg)	0.000	0.996	0.004
M62.45 Contracture of muscle (Pelvic region and thigh)	0.000	0.996	0.004
M62.44 Contracture of muscle (Hand)	0.000	0.996	0.004
M62.43 Contracture of muscle (Forearm)	0.000	0.996	0.004
M62.42 Contracture of muscle (Upper arm)	0.000	0.996	0.004
M62.41 Contracture of muscle (Shoulder region)	0.000	0.996	0.004
M62.40 Contracture of muscle (Multiple sites)	0.000	0.996	0.004
R90.0 Intracranial space-occupying lesion	0.000	0.996	0.004
M62.09 Diastasis of muscle (Site unspecified)	0.000	0.996	0.004
M62.07 Diastasis of muscle (Ankle and foot)	0.000	0.996	0.004
M62.06 Diastasis of muscle (Lower leg)	0.000	0.996	0.004
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.000	0.996	0.004
M62.04 Diastasis of muscle (Hand)	0.000	0.996	0.004
M62.03 Diastasis of muscle (Forearm)	0.000	0.996	0.004
M62.02 Diastasis of muscle (Upper arm)	0.000	0.996	0.004
M62.01 Diastasis of muscle (Shoulder region)	0.000	0.996	0.004
M62.00 Diastasis of muscle (Multiple sites)	0.000	0.996	0.004
T78.8 Other adverse effects, not elsewhere classified	0.000	0.996	0.004
J13 Pneumonia due to Streptococcus pneumoniae	0.000	0.996	0.004
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.996	0.004
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.996	0.004
S20.4 Other superficial injuries of back wall of thorax	0.000	0.996	0.004
M62.08 Diastasis of muscle (Other)	0.000	0.996	0.004
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.000	0.996	0.003
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.000	0.996	0.003
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.000	0.996	0.003
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.000	0.996	0.003
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.000	0.996	0.003
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.000	0.996	0.003
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.000	0.996	0.003
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.000	0.996	0.003
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.000	0.996	0.003
J35.1 Hypertrophy of tonsils	0.004	0.996	0.000
D52 Folate deficiency anaemia	0.000	0.996	0.004
M62.66 Muscle strain (Lower leg)	0.000	0.996	0.003
M60-M63 Disorders of muscles	0.000	0.996	0.004
M62.69 Muscle strain (Site unspecified)	0.000	0.996	0.003
M62.67 Muscle strain (Ankle and foot)	0.000	0.996	0.003
M62.64 Muscle strain (Hand)	0.000	0.996	0.003
M62.63 Muscle strain (Forearm)	0.000	0.996	0.003
M62.62 Muscle strain (Upper arm)	0.000	0.996	0.003
M62.61 Muscle strain (Shoulder region)	0.000	0.996	0.003
M62.60 Muscle strain (Multiple sites)	0.000	0.996	0.003
S92.70 Multiple fractures of foot (closed)	0.003	0.996	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.997	0.003
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.000	0.997	0.003
M62.65 Muscle strain (Pelvic region and thigh)	0.000	0.997	0.003
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.003
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.003
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.997	0.003
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.003
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.003
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.003
S91.3 Open wound of other parts of foot	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.000	0.997	0.003
M25.0 Haemarthrosis	0.003	0.997	0.000
M62.68 Muscle strain (Other)	0.000	0.997	0.003
M60 Myositis	0.000	0.997	0.003
D53 Other nutritional anaemias	0.000	0.997	0.003
R94.4 Abnormal results of kidney function studies	0.000	0.997	0.003
S92.7 Multiple fractures of foot	0.003	0.997	0.000
V48.4 Person injured while boarding or alighting	0.000	0.997	0.003
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
Z29 Need for other prophylactic measures	0.000	0.997	0.003
Z29.8 Other specified prophylactic measures	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
M60.9 Myositis, unspecified	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
F20.9 Schizophrenia, unspecified	0.000	0.997	0.003
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.997	0.003
D52.8 Other folate deficiency anaemias	0.000	0.997	0.003
D52.1 Drug-induced folate deficiency anaemia	0.000	0.997	0.003
D52.0 Dietary folate deficiency anaemia	0.000	0.997	0.003
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.997	0.003
Z29.2 Other prophylactic chemotherapy	0.000	0.997	0.003
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.997	0.003
F20 Schizophrenia	0.000	0.997	0.003
S91 Open wound of ankle and foot	0.003	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.003	0.997	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.000	0.997	0.003
M61 Calcification and ossification of muscle	0.000	0.997	0.003
R84.5 Abnormal microbiological findings	0.003	0.997	0.000
M60.99 Myositis, unspecified (Site unspecified)	0.000	0.997	0.003
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
M60.0 Infective myositis	0.000	0.997	0.003
S92 Fracture of foot, except ankle	0.003	0.997	0.000
F20.0 Paranoid schizophrenia	0.000	0.997	0.003
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.997	0.003
I42.2 Other hypertrophic cardiomyopathy	0.003	0.997	0.000
R94.5 Abnormal results of liver function studies	0.000	0.997	0.003
S92.4 Fracture of great toe	0.003	0.997	0.000
M25.09 Haemarthrosis (Site unspecified)	0.002	0.997	0.000
M25.08 Haemarthrosis (Other)	0.002	0.997	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.002	0.997	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.002	0.997	0.000
M25.04 Haemarthrosis (Hand)	0.002	0.997	0.000
M25.03 Haemarthrosis (Forearm)	0.002	0.997	0.000
M25.02 Haemarthrosis (Upper arm)	0.002	0.997	0.000
M25.01 Haemarthrosis (Shoulder region)	0.002	0.997	0.000
M25.00 Haemarthrosis (Multiple sites)	0.002	0.997	0.000
Q44.6 Cystic disease of liver	0.000	0.997	0.003
O90 Complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.003	0.997	0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified	0.000	0.997	0.002
M60.1 Interstitial myositis	0.000	0.997	0.002
M60.05 Infective myositis (Pelvic region and thigh)	0.000	0.997	0.003
D53.8 Other specified nutritional anaemias	0.000	0.997	0.002
D53.2 Scorbutic anaemia	0.000	0.997	0.002
D53.0 Protein deficiency anaemia	0.000	0.997	0.002
J38.7 Other diseases of larynx	0.003	0.997	0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
M60.8 Other myositis	0.000	0.997	0.002
R25.3 Fasciculation	0.000	0.997	0.003
S12.1 Fracture of second cervical vertebra	0.000	0.997	0.003
H92 Otalgia and effusion of ear	0.002	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.997	0.000
B99 Other and unspecified infectious diseases	0.000	0.997	0.003
S92.40 Fracture of great toe (closed)	0.002	0.997	0.000
F22.0 Delusional disorder	0.000	0.997	0.002
F25 Schizoaffective disorders	0.000	0.997	0.002
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
O62.2 Other uterine inertia	0.000	0.997	0.002
F22 Persistent delusional disorders	0.000	0.997	0.002
H33.2 Serous retinal detachment	0.002	0.998	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.998	0.002
D52.9 Folate deficiency anaemia, unspecified	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.002
S12.2 Fracture of other specified cervical vertebra	0.000	0.998	0.002
M60.98 Myositis, unspecified (Other)	0.000	0.998	0.002
M60.97 Myositis, unspecified (Ankle and foot)	0.000	0.998	0.002
M60.94 Myositis, unspecified (Hand)	0.000	0.998	0.002
M60.93 Myositis, unspecified (Forearm)	0.000	0.998	0.002
M60.92 Myositis, unspecified (Upper arm)	0.000	0.998	0.002
M60.91 Myositis, unspecified (Shoulder region)	0.000	0.998	0.002
M60.90 Myositis, unspecified (Multiple sites)	0.000	0.998	0.002
R25.1 Tremor, unspecified	0.000	0.998	0.002
H65 Nonsuppurative otitis media	0.002	0.998	0.000
M60.96 Myositis, unspecified (Lower leg)	0.000	0.998	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.998	0.002
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.002	0.998	0.000
F20.5 Residual schizophrenia	0.000	0.998	0.002
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.000	0.998	0.002
F20.8 Other schizophrenia	0.000	0.998	0.002
F20.6 Simple schizophrenia	0.000	0.998	0.002
F20.4 Postschizophrenic depression	0.000	0.998	0.002
F20.3 Undifferentiated schizophrenia	0.000	0.998	0.002
F20.2 Catatonic schizophrenia	0.000	0.998	0.002
F20.1 Hebephrenic schizophrenia	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.000	0.998	0.002
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
M61.9 Calcification and ossification of muscle, unspecified	0.000	0.998	0.002
M61.5 Other ossification of muscle	0.000	0.998	0.002
M61.4 Other calcification of muscle	0.000	0.998	0.002
M61.3 Calcification and ossification of muscles associated with burns	0.000	0.998	0.002
M61.2 Paralytic calcification and ossification of muscle	0.000	0.998	0.002
M61.1 Myositis ossificans progressiva	0.000	0.998	0.002
M61.0 Myositis ossificans traumatica	0.000	0.998	0.002
M63.8 Other disorders of muscle in diseases classified elsewhere	0.000	0.998	0.002
M63.3 Myositis in sarcoidosis	0.000	0.998	0.002
M63.2 Myositis in other infectious diseases classified elsewhere	0.000	0.998	0.002
M63.1 Myositis in protozoal and parasitic infections classified elsewhere	0.000	0.998	0.002
M63.0 Myositis in bacterial diseases classified elsewhere	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
R94 Abnormal results of function studies	0.000	0.998	0.002
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.998	0.002
E87.5 Hyperkalaemia	0.000	0.998	0.002
S91.0 Open wound of ankle	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
R94.2 Abnormal results of pulmonary function studies	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.000	0.998	0.002
N50 Other disorders of male genital organs	0.002	0.998	0.000
S92.5 Fracture of other toe	0.002	0.998	0.000
M60.09 Infective myositis (Site unspecified)	0.000	0.998	0.002
M60.07 Infective myositis (Ankle and foot)	0.000	0.998	0.002
M60.06 Infective myositis (Lower leg)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations