TreeWAS – Variant ID: rs2302387

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.000	1.000
K80 Cholelithiasis	0.000	0.000	1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.000	1.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.000	1.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.000	1.000
K81 Cholecystitis	0.000	0.000	1.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.002	0.998
K83 Other diseases of biliary tract	0.000	0.004	0.996
K86 Other diseases of pancreas	0.000	0.005	0.995
K81.9 Cholecystitis, unspecified	0.000	0.009	0.991
K83.8 Other specified diseases of biliary tract	0.000	0.014	0.986
K86.1 Other chronic pancreatitis	0.000	0.040	0.960
K81.0 Acute cholecystitis	0.000	0.050	0.950
K86.2 Cyst of pancreas	0.000	0.057	0.943
K81.1 Chronic cholecystitis	0.000	0.062	0.938
K85 Acute pancreatitis	0.000	0.121	0.879
K83.0 Cholangitis	0.000	0.142	0.858
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.148	0.852
K80.4 Calculus of bile duct with cholecystitis	0.000	0.169	0.831
K83.1 Obstruction of bile duct	0.000	0.180	0.820
K83.9 Disease of biliary tract, unspecified	0.000	0.190	0.810
K85.1 Biliary acute pancreatitis	0.000	0.203	0.797
K82 Other diseases of gallbladder	0.000	0.220	0.780
K86.3 Pseudocyst of pancreas	0.000	0.227	0.773
K81.8 Other cholecystitis	0.000	0.240	0.760
K86.9 Disease of pancreas, unspecified	0.000	0.249	0.750
K80.3 Calculus of bile duct with cholangitis	0.000	0.283	0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.283	0.717
K83.5 Biliary cyst	0.000	0.286	0.714
K83.3 Fistula of bile duct	0.000	0.286	0.714
K83.2 Perforation of bile duct	0.000	0.286	0.714
K85.2 Alcohol-induced acute pancreatitis	0.000	0.334	0.666
K80.8 Other cholelithiasis	0.000	0.336	0.664
K82.2 Perforation of gallbladder	0.000	0.365	0.635
K85.3 Drug-induced acute pancreatitis	0.000	0.369	0.630
K85.0 Idiopathic acute pancreatitis	0.000	0.369	0.630
K85.9 Acute pancreatitis, unspecified	0.000	0.379	0.621
K82.3 Fistula of gallbladder	0.000	0.379	0.621
K82.9 Disease of gallbladder, unspecified	0.000	0.410	0.590
K85.8 Other acute pancreatitis	0.000	0.414	0.586
K82.8 Other specified diseases of gallbladder	0.000	0.416	0.584
K83.4 Spasm of sphincter of Oddi	0.000	0.450	0.550
K82.0 Obstruction of gallbladder	0.000	0.454	0.546
K86.8 Other specified diseases of pancreas	0.000	0.475	0.525
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.486	0.514
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.486	0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.486	0.514
K82.4 Cholesterolosis of gallbladder	0.000	0.501	0.499
K82.1 Hydrops of gallbladder	0.000	0.544	0.456
K90-K93 Other diseases of the digestive system	0.000	0.956	0.044
K70-K77 Diseases of liver	0.000	0.956	0.044
Chapter XI Diseases of the digestive system	0.000	0.957	0.043
K70 Alcoholic liver disease	0.000	0.958	0.042
K72 Hepatic failure, not elsewhere classified	0.000	0.958	0.042
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.960	0.040
K90 Intestinal malabsorption	0.000	0.960	0.040
K72.0 Acute and subacute hepatic failure	0.000	0.960	0.040
K70.3 Alcoholic cirrhosis of liver	0.000	0.961	0.039
K92 Other diseases of digestive system	0.000	0.962	0.038
K90.0 Coeliac disease	0.000	0.963	0.037
K74 Fibrosis and cirrhosis of liver	0.000	0.963	0.037
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.963	0.037
K70.0 Alcoholic fatty liver	0.000	0.964	0.036
K92.1 Melaena	0.000	0.965	0.035
K72.9 Hepatic failure, unspecified	0.000	0.966	0.034
K91.3 Postoperative intestinal obstruction	0.000	0.966	0.034
K91.4 Colostomy and enterostomy malfunction	0.000	0.966	0.034
K70.4 Alcoholic hepatic failure	0.000	0.967	0.033
K92.9 Disease of digestive system, unspecified	0.000	0.967	0.033
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.968	0.032
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.968	0.032
K77 Liver disorders in diseases classified elsewhere	0.000	0.968	0.032
K71 Toxic liver disease	0.000	0.968	0.032
K70.1 Alcoholic hepatitis	0.000	0.968	0.032
K73 Chronic hepatitis, not elsewhere classified	0.000	0.969	0.031
K74.0 Hepatic fibrosis	0.000	0.969	0.031
K72.1 Chronic hepatic failure	0.000	0.970	0.030
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.970	0.030
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.970	0.030
K90.8 Other intestinal malabsorption	0.000	0.970	0.030
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.970	0.030
K74.6 Other and unspecified cirrhosis of liver	0.000	0.971	0.029
K74.3 Primary biliary cirrhosis	0.000	0.971	0.029
K91.5 Postcholecystectomy syndrome	0.000	0.971	0.029
K75 Other inflammatory liver diseases	0.000	0.971	0.029
K90.3 Pancreatic steatorrhoea	0.000	0.971	0.029
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.971	0.029
K90.1 Tropical sprue	0.000	0.971	0.029
K92.8 Other specified diseases of digestive system	0.000	0.972	0.028
K70.9 Alcoholic liver disease, unspecified	0.000	0.972	0.028
K74.4 Secondary biliary cirrhosis	0.000	0.973	0.027
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.973	0.027
K74.1 Hepatic sclerosis	0.000	0.973	0.027
K91.1 Postgastric surgery syndromes	0.000	0.975	0.025
K74.5 Biliary cirrhosis, unspecified	0.000	0.975	0.024
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.977	0.023
K93.1 Megacolon in Chagas' disease	0.000	0.977	0.023
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.977	0.023
K71.9 Toxic liver disease, unspecified	0.000	0.977	0.023
K71.8 Toxic liver disease with other disorders of liver	0.000	0.977	0.023
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.977	0.023
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.977	0.023
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.977	0.023
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.977	0.023
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.977	0.023
K71.2 Toxic liver disease with acute hepatitis	0.000	0.977	0.023
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.977	0.023
K71.0 Toxic liver disease with cholestasis	0.000	0.977	0.023
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.977	0.023
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.977	0.023
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.977	0.023
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.977	0.023
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.977	0.023
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.977	0.023
K73.9 Chronic hepatitis, unspecified	0.000	0.977	0.023
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.977	0.023
K75.0 Abscess of liver	0.000	0.978	0.021
K75.8 Other specified inflammatory liver diseases	0.000	0.979	0.021
K75.9 Inflammatory liver disease, unspecified	0.000	0.979	0.021
K50-K52 Noninfective enteritis and colitis	0.000	0.979	0.021
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.979	0.021
K75.2 Nonspecific reactive hepatitis	0.000	0.979	0.021
K75.1 Phlebitis of portal vein	0.000	0.979	0.021
K90.9 Intestinal malabsorption, unspecified	0.000	0.980	0.020
K92.0 Haematemesis	0.000	0.981	0.019
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.981	0.019
K52 Other non-infective gastro-enteritis and colitis	0.000	0.981	0.019
D86.9 Sarcoidosis, unspecified	0.000	0.983	0.017
D86.0 Sarcoidosis of lung	0.000	0.983	0.017
D86 Sarcoidosis	0.000	0.984	0.016
K75.4 Autoimmune hepatitis	0.000	0.984	0.016
N95.8 Other specified menopausal and perimenopausal disorders	0.015	0.985	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.985	0.015
K76 Other diseases of liver	0.000	0.985	0.015
K52.3 Indeterminate colitis	0.000	0.985	0.015
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.986	0.014
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.986	0.014
D86.8 Sarcoidosis of other and combined sites	0.000	0.987	0.013
K52.1 Toxic gastro-enteritis and colitis	0.000	0.987	0.013
K65-K67 Diseases of peritoneum	0.000	0.987	0.013
D86.1 Sarcoidosis of lymph nodes	0.000	0.987	0.013
D86.3 Sarcoidosis of skin	0.000	0.988	0.012
Z97.8 Presence of other specified devices	0.000	0.988	0.012
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.988	0.012
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.989	0.011
N81.3 Complete uterovaginal prolapse	0.011	0.989	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.989	0.011
K76.4 Peliosis hepatis	0.000	0.989	0.011
K76.3 Infarction of liver	0.000	0.989	0.011
K76.2 Central haemorrhagic necrosis of liver	0.000	0.989	0.011
Z97.0 Presence of artificial eye	0.000	0.989	0.011
Z97 Presence of other devices	0.000	0.989	0.011
Z97.4 Presence of external hearing-aid	0.000	0.989	0.011
K76.7 Hepatorenal syndrome	0.000	0.990	0.010
K76.9 Liver disease, unspecified	0.000	0.990	0.010
K76.1 Chronic passive congestion of liver	0.000	0.990	0.009
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.991	0.009
K51 Ulcerative colitis	0.000	0.991	0.009
O26.8 Other specified pregnancy-related conditions	0.009	0.991	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.009	0.991	0.000
N81.4 Uterovaginal prolapse, unspecified	0.009	0.991	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
K76.6 Portal hypertension	0.000	0.991	0.009
N81 Female genital prolapse	0.009	0.991	0.000
K51.4 Pseudopolyposis of colon	0.000	0.991	0.009
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
Z97.3 Presence of spectacles and contact lenses	0.000	0.992	0.008
Z97.1 Presence of artificial limb (complete)(partial)	0.000	0.992	0.008
O26 Maternal care for other conditions predominantly related to pregnancy	0.008	0.992	0.000
Z97.2 Presence of dental prosthetic device (complete)(partial)	0.000	0.992	0.008
N81.5 Vaginal enterocele	0.008	0.992	0.000
N81.0 Female urethrocele	0.008	0.992	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.992	0.008
O36.9 Maternal care for foetal problem, unspecified	0.007	0.993	0.000
N81.6 Rectocele	0.007	0.993	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.000	0.993	0.007
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.993	0.007
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.993	0.007
K67.3 Tuberculous peritonitis	0.000	0.993	0.007
K67.2 Syphilitic peritonitis	0.000	0.993	0.007
K67.1 Gonococcal peritonitis	0.000	0.993	0.007
K67.0 Chlamydial peritonitis	0.000	0.993	0.007
T79 Certain early complications of trauma, not elsewhere classified	0.007	0.993	0.000
O26.2 Pregnancy care of habitual aborter	0.007	0.993	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.993	0.007
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.007	0.993	0.000
K35-K38 Diseases of appendix	0.001	0.993	0.006
O94-O99 Other obstetric conditions, not elsewhere classified	0.006	0.994	0.000
T79.8 Other early complications of trauma	0.006	0.994	0.000
O26.0 Excessive weight gain in pregnancy	0.006	0.994	0.000
N81.9 Female genital prolapse, unspecified	0.006	0.994	0.000
O36 Maternal care for other known or suspected foetal problems	0.006	0.994	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O26.5 Maternal hypotension syndrome	0.006	0.994	0.000
O26.4 Herpes gestationis	0.006	0.994	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.006	0.994	0.000
O26.1 Low weight gain in pregnancy	0.006	0.994	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.994	0.006
N81.8 Other female genital prolapse	0.006	0.994	0.000
D37.5 Rectum	0.000	0.994	0.006
T79.7 Traumatic subcutaneous emphysema	0.006	0.994	0.000
K51.5 Mucosal proctocolitis	0.000	0.994	0.006
O20-O29 Other maternal disorders predominantly related to pregnancy	0.006	0.994	0.000
T79.6 Traumatic ischaemia of muscle	0.005	0.994	0.000
O36.1 Maternal care for other isoimmunisation	0.005	0.995	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.995	0.005
M35.0 Sicca syndrome [Sjogren]	0.005	0.995	0.000
T79.9 Unspecified early complication of trauma	0.005	0.995	0.000
T79.5 Traumatic anuria	0.005	0.995	0.000
T79.4 Traumatic shock	0.005	0.995	0.000
T79.2 Traumatic secondary and recurrent haemorrhage	0.005	0.995	0.000
T79.1 Fat embolism (traumatic)	0.005	0.995	0.000
T79.0 Air embolism (traumatic)	0.005	0.995	0.000
O26.9 Pregnancy-related condition, unspecified	0.005	0.995	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
S93.0 Dislocation of ankle joint	0.005	0.995	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.005	0.995	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.995	0.005
C44.5 Skin of trunk	0.000	0.995	0.005
S93.1 Dislocation of toe(s)	0.005	0.995	0.000
K76.8 Other specified diseases of liver	0.000	0.995	0.005
K38 Other diseases of appendix	0.000	0.995	0.005
K51.8 Other ulcerative colitis	0.000	0.995	0.005
K65 Peritonitis	0.000	0.995	0.005
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O28 Abnormal findings on antenatal screening of mother	0.005	0.995	0.000
O97 Death from sequelae of direct obstetric causes	0.005	0.995	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.005	0.995	0.000
O95 Obstetric death of unspecified cause	0.005	0.995	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.005	0.995	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O14.9 Preeclampsia, unspecified	0.005	0.995	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.005	0.995	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.005	0.995	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O16 Unspecified maternal hypertension	0.005	0.995	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.005	0.995	0.000
O36.4 Maternal care for intra-uterine death	0.005	0.995	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.005	0.995	0.000
O36.2 Maternal care for hydrops foetalis	0.005	0.995	0.000
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.995	0.005
O22 Venous complications in pregnancy	0.004	0.995	0.000
O30 Multiple gestation	0.004	0.995	0.000
O48 Prolonged pregnancy	0.005	0.995	0.000
K38.1 Appendicular concretions	0.000	0.995	0.004
O36.5 Maternal care for poor foetal growth	0.004	0.996	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.004	0.996	0.000
O30.0 Twin pregnancy	0.004	0.996	0.000
O40 Polyhydramnios	0.004	0.996	0.000
O36.6 Maternal care for excessive foetal growth	0.004	0.996	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.996	0.004
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
O14.1 Severe preeclampsia	0.004	0.996	0.000
O29 Complications of anaesthesia during pregnancy	0.004	0.996	0.000
O25 Malnutrition in pregnancy	0.004	0.996	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.004	0.996	0.000
S91.0 Open wound of ankle	0.004	0.996	0.000
O36.8 Maternal care for other specified foetal problems	0.004	0.996	0.000
S91 Open wound of ankle and foot	0.004	0.996	0.000
S90 Superficial injury of ankle and foot	0.004	0.996	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.004	0.996	0.000
L98.0 Pyogenic granuloma	0.004	0.996	0.000
K36 Other appendicitis	0.001	0.996	0.003
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.004	0.996	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
S93.4 Sprain and strain of ankle	0.004	0.996	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.004	0.996	0.000
S93.5 Sprain and strain of toe(s)	0.004	0.996	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.004	0.996	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.004	0.996	0.000
N81.2 Incomplete uterovaginal prolapse	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.004	0.996	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.004	0.996	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.996	0.004
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.004	0.996	0.000
S91.1 Open wound of toe(s) without damage to nail	0.004	0.996	0.000
D83 Common variable immunodeficiency	0.000	0.996	0.004
D82 Immunodeficiency associated with other major defects	0.000	0.996	0.004
D81 Combined immunodeficiencies	0.000	0.996	0.004
Z51.3 Blood transfusion without reported diagnosis	0.000	0.996	0.004
R06.5 Mouth breathing	0.004	0.996	0.000
O20 Haemorrhage in early pregnancy	0.004	0.996	0.000
K38.3 Fistula of appendix	0.000	0.996	0.003
K38.2 Diverticulum of appendix	0.000	0.996	0.003
K38.0 Hyperplasia of appendix	0.000	0.996	0.003
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.996	0.004
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.996	0.004
O44 Placenta praevia	0.004	0.996	0.000
O96.9 Death from unspecified obstetric cause	0.004	0.996	0.000
O96.1 Death from indirect obstetric cause	0.004	0.996	0.000
O96.0 Death from direct obstetric cause	0.004	0.996	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.004	0.996	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.004	0.996	0.000
O97.0 Death from sequelae of direct obstetric cause	0.004	0.996	0.000
S97 Crushing injury of ankle and foot	0.004	0.996	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.004	0.996	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.004	0.996	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.004	0.996	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.004	0.996	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.004	0.996	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.004	0.996	0.000
O85-O92 Complications predominantly related to the puerperium	0.004	0.996	0.000
R94.5 Abnormal results of liver function studies	0.000	0.996	0.004
O22.0 Varicose veins of lower extremity in pregnancy	0.004	0.996	0.000
O14.2 HELLP syndrome	0.004	0.996	0.000
O15 Eclampsia	0.004	0.996	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.004	0.996	0.000
O44.1 Placenta praevia with haemorrhage	0.004	0.996	0.000
C62.9 Testis, unspecified	0.004	0.996	0.000
D84 Other immunodeficiencies	0.000	0.996	0.003
O45 Premature separation of placenta [abruptio placentae]	0.004	0.996	0.000
S90.8 Other superficial injuries of ankle and foot	0.004	0.996	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.996	0.004
O20.9 Haemorrhage in early pregnancy, unspecified	0.004	0.996	0.000
D47.2 Monoclonal gammopathy	0.000	0.996	0.004
O22.4 Haemorrhoids in pregnancy	0.003	0.996	0.000
S99 Other and unspecified injuries of ankle and foot	0.003	0.996	0.000
O33 Maternal care for known or suspected disproportion	0.003	0.996	0.000
O22.9 Venous complication in pregnancy, unspecified	0.003	0.996	0.000
O22.8 Other venous complications in pregnancy	0.003	0.996	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.003	0.996	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.003	0.996	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.003	0.996	0.000
O22.1 Genital varices in pregnancy	0.003	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.996	0.000
O30.9 Multiple gestation, unspecified	0.003	0.996	0.000
O30.8 Other multiple gestation	0.003	0.996	0.000
O30.2 Quadruplet pregnancy	0.003	0.996	0.000
O30.1 Triplet pregnancy	0.003	0.996	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.003	0.996	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.003	0.996	0.000
O34.1 Maternal care for tumour of corpus uteri	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.003	0.997	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.003	0.997	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.003	0.997	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.003	0.997	0.000
E10.1 With ketoacidosis	0.000	0.997	0.003
K38.8 Other specified diseases of appendix	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
D47.4 Osteomyelofibrosis	0.000	0.997	0.003
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.003	0.997	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.6 Failed or difficult intubation during pregnancy	0.003	0.997	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.003	0.997	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.003	0.997	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.003	0.997	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.003	0.997	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.003	0.997	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.003	0.997	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.003	0.997	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.003	0.997	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.003	0.997	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.003	0.997	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.003	0.997	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.000	0.997	0.003
S90.3 Contusion of other and unspecified parts of foot	0.003	0.997	0.000
S90.0 Contusion of ankle	0.003	0.997	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
S52.00 Fracture of upper end of ulna (closed)	0.000	0.997	0.003
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.997	0.003
O12.0 Gestational oedema	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.000	0.997	0.003
Z98.2 Presence of cerebrospinal fluid drainage device	0.000	0.997	0.003
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
K38.9 Disease of appendix, unspecified	0.001	0.997	0.003
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.003	0.997	0.000
O23 Infections of genito-urinary tract in pregnancy	0.003	0.997	0.000
E10.2 With renal complications	0.000	0.997	0.003
O92 Other disorders of breast and lactation associated with childbirth	0.003	0.997	0.000
S92 Fracture of foot, except ankle	0.003	0.997	0.000
O12.1 Gestational proteinuria	0.003	0.997	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.003	0.997	0.000
S90.2 Contusion of toe(s) with damage to nail	0.003	0.997	0.000
S90.1 Contusion of toe(s) without damage to nail	0.003	0.997	0.000
O21 Excessive vomiting in pregnancy	0.003	0.997	0.000
C90.0 Multiple myeloma	0.000	0.997	0.003
S93.40 Sprain of unspecified ligament of ankle	0.003	0.997	0.000
O41 Other disorders of amniotic fluid and membranes	0.003	0.997	0.000
O12.2 Gestational oedema with proteinuria	0.003	0.997	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.997	0.003
D81.8 Other combined immunodeficiencies	0.000	0.997	0.003
D81.7 Major histocompatibility complex class II deficiency	0.000	0.997	0.003
D81.6 Major histocompatibility complex class I deficiency	0.000	0.997	0.003
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.997	0.003
D81.4 Nezelof's syndrome	0.000	0.997	0.003
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.997	0.003
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.997	0.003
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.997	0.003
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.997	0.003
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.997	0.003
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.997	0.003
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.997	0.003
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.997	0.003
D82.2 Immunodeficiency with short-limbed stature	0.000	0.997	0.003
D82.1 Di George's syndrome	0.000	0.997	0.003
D82.0 Wiskott-Aldrich syndrome	0.000	0.997	0.003
D83.9 Common variable immunodeficiency, unspecified	0.000	0.997	0.003
D83.8 Other common variable immunodeficiencies	0.000	0.997	0.003
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.997	0.003
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.997	0.003
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.997	0.003
O14.0 Moderate preeclampsia	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
D89.3 Immune reconstitution syndrome	0.000	0.997	0.003
D89.1 Cryoglobulinaemia	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
E10 Insulin-dependent diabetes mellitus	0.000	0.997	0.003
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
D47.1 Chronic myeloproliferative disease	0.000	0.997	0.003
T79-T79 Certain early complications of trauma	0.003	0.997	0.000
K65.0 Acute peritonitis	0.000	0.997	0.003
O89 Complications of anaesthesia during the puerperium	0.003	0.997	0.000
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
O34.0 Maternal care for congenital malformation of uterus	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
S97.1 Crushing injury of toe(s)	0.003	0.997	0.000
S97.0 Crushing injury of ankle	0.003	0.997	0.000
O91 Infections of breast associated with childbirth	0.003	0.997	0.000
O88 Obstetric embolism	0.003	0.997	0.000
O85 Puerperal sepsis	0.003	0.997	0.000
E10.3 With ophthalmic complications	0.000	0.997	0.003
S92.4 Fracture of great toe	0.003	0.997	0.000
K66 Other disorders of peritoneum	0.000	0.997	0.003
O15.9 Eclampsia, unspecified as to time period	0.003	0.997	0.000
O15.2 Eclampsia in the puerperium	0.003	0.997	0.000
O15.1 Eclampsia in labour	0.003	0.997	0.000
O15.0 Eclampsia in pregnancy	0.003	0.997	0.000
O31.8 Other complications specific to multiple gestation	0.003	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.997	0.000
O31.0 Papyraceous foetus	0.003	0.997	0.000
O92.1 Cracked nipple associated with childbirth	0.003	0.997	0.000
E10.5 With peripheral circulatory complications	0.000	0.997	0.003
Q50.4 Embryonic cyst of Fallopian tube	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.000	0.997	0.003
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.997	0.003
O45.8 Other premature separation of placenta	0.003	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.003	0.997	0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.000	0.997	0.003
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.000	0.997	0.003
O34.4 Maternal care for other abnormalities of cervix	0.003	0.997	0.000
O90 Complications of the puerperium, not elsewhere classified	0.003	0.997	0.000
O87 Venous complications in the puerperium	0.003	0.997	0.000
O20.8 Other haemorrhage in early pregnancy	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.003	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.003	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.003	0.997	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.003	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.003	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.003	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.003	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.003	0.997	0.000
O45.9 Premature separation of placenta, unspecified	0.003	0.997	0.000
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.003	0.997	0.000
D84.9 Immunodeficiency, unspecified	0.000	0.997	0.003
O46.0 Antepartum haemorrhage with coagulation defect	0.003	0.997	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.003	0.997	0.000
O34.6 Maternal care for abnormality of vagina	0.003	0.997	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.003	0.997	0.000
O86 Other puerperal infections	0.003	0.997	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.997	0.000
S94.1 Injury of medial plantar nerve	0.002	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations