TreeWAS – Variant ID: rs2317961

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J35.0 Chronic tonsillitis	0.000	0.428	0.572
J35 Chronic diseases of tonsils and adenoids	0.000	0.450	0.550
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.468	0.532
J35.1 Hypertrophy of tonsils	0.000	0.528	0.472
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.541	0.459
J35.2 Hypertrophy of adenoids	0.000	0.575	0.425
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.605	0.394
T39.1 4-Aminophenol derivatives	0.248	0.752	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.238	0.762	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.232	0.768	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.227	0.773	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.224	0.776	0.000
T43.2 Other and unspecified antidepressants	0.222	0.778	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.214	0.786	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.211	0.789	0.000
T36 Poisoning by systemic antibiotics	0.206	0.794	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.198	0.802	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.188	0.812	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.187	0.813	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.185	0.815	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.180	0.820	0.000
T50.8 Diagnostic agents	0.179	0.821	0.000
T43.6 Psychostimulants with abuse potential	0.175	0.825	0.000
T50.4 Drugs affecting uric acid metabolism	0.173	0.826	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.173	0.827	0.000
T39.4 Antirheumatics, not elsewhere classified	0.171	0.829	0.000
T39.2 Pyrazolone derivatives	0.171	0.829	0.000
T36.0 Penicillins	0.169	0.831	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.167	0.833	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.166	0.833	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.165	0.835	0.000
T36.4 Tetracyclines	0.164	0.836	0.000
T50.7 Analeptics and opioid receptor antagonists	0.163	0.837	0.000
T50.5 Appetite depressants	0.163	0.837	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.163	0.837	0.000
T50.0 Mineralocorticoids and their antagonists	0.163	0.837	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.162	0.838	0.000
T50.1 Loop [high-ceiling] diuretics	0.161	0.839	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.161	0.839	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.161	0.839	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.160	0.840	0.000
T45.0 Antiallergic and antiemetic drugs	0.160	0.840	0.000
T36.8 Other systemic antibiotics	0.157	0.843	0.000
T45.2 Vitamins, not elsewhere classified	0.156	0.844	0.000
T43.9 Psychotropic drug, unspecified	0.156	0.844	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.156	0.844	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.155	0.845	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.154	0.845	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.154	0.846	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.154	0.846	0.000
T36.3 Macrolides	0.152	0.848	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.150	0.850	0.000
T36.9 Systemic antibiotic, unspecified	0.148	0.852	0.000
T36.7 Antifungal antibiotics, systemically used	0.148	0.852	0.000
T36.6 Rifamycins	0.148	0.852	0.000
T36.5 Aminoglycosides	0.148	0.852	0.000
T36.2 Chloramphenicol group	0.148	0.852	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.143	0.856	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.142	0.858	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.139	0.861	0.000
H40.9 Glaucoma, unspecified	0.139	0.861	0.000
T38.5 Other oestrogens and progestogens	0.138	0.862	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.136	0.864	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.135	0.865	0.000
T37.5 Antiviral drugs	0.135	0.865	0.000
T37.4 Anthelminthics	0.135	0.865	0.000
T37.3 Other antiprotozoal drugs	0.135	0.865	0.000
T37.1 Antimycobacterial drugs	0.135	0.865	0.000
T37.0 Sulphonamides	0.135	0.865	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.134	0.866	0.000
T45.8 Other primarily systemic and haematological agents	0.134	0.866	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.134	0.866	0.000
T45.6 Fibrinolysis-affecting drugs	0.134	0.866	0.000
T45.3 Enzymes, not elsewhere classified	0.134	0.866	0.000
T45.4 Iron and its compounds	0.134	0.866	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.133	0.867	0.000
T48.4 Expectorants	0.133	0.867	0.000
T48.3 Antitussives	0.133	0.867	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.133	0.867	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.133	0.867	0.000
T48.0 Oxytocic drugs	0.133	0.867	0.000
T48.5 Anti-common-cold drugs	0.127	0.872	0.000
T38.9 Other and unspecified hormone antagonists	0.124	0.876	0.000
T38.7 Androgens and anabolic congeners	0.124	0.876	0.000
T38.4 Oral contraceptives	0.124	0.876	0.000
T38.2 Antithyroid drugs	0.124	0.876	0.000
T38.0 Glucocorticoids and synthetic analogues	0.124	0.876	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.124	0.876	0.000
T47.2 Stimulant laxatives	0.123	0.877	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.121	0.879	0.000
T41.5 Therapeutic gases	0.119	0.880	0.000
T41.4 Anaesthetic, unspecified	0.119	0.880	0.000
T41.3 Local anaesthetics	0.119	0.880	0.000
T41.1 Intravenous anaesthetics	0.119	0.880	0.000
T41.0 Inhaled anaesthetics	0.119	0.880	0.000
T41.2 Other and unspecified general anaesthetics	0.119	0.880	0.000
T38.1 Thyroid hormones and substitutes	0.117	0.883	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.117	0.883	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.116	0.883	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.116	0.883	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.116	0.883	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.116	0.883	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.116	0.883	0.000
T44.0 Anticholinesterase agents	0.116	0.883	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.116	0.884	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.116	0.884	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.115	0.885	0.000
T49.9 Topical agent, unspecified	0.115	0.885	0.000
T49.8 Other topical agents	0.115	0.885	0.000
T49.7 Dental drugs, topically applied	0.115	0.885	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.115	0.885	0.000
T49.5 Ophthalmological drugs and preparations	0.115	0.885	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.115	0.885	0.000
T49.3 Emollients, demulcents and protectants	0.115	0.885	0.000
T49.2 Local astringents and local detergents	0.115	0.885	0.000
T49.1 Antipruritics	0.115	0.885	0.000
T47.6 Antidiarrhoeal drugs	0.113	0.887	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.112	0.888	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.112	0.888	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.112	0.888	0.000
T47.7 Emetics	0.112	0.888	0.000
T47.5 Digestants	0.112	0.888	0.000
T47.3 Saline and osmotic laxatives	0.112	0.888	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.109	0.891	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.106	0.893	0.000
T47.4 Other laxatives	0.106	0.894	0.000
T39.0 Salicylates	0.105	0.895	0.000
Z29.2 Other prophylactic chemotherapy	0.105	0.895	0.000
T40.1 Heroin	0.104	0.896	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.100	0.900	0.000
T40.8 Lysergide [LSD]	0.100	0.900	0.000
T40.7 Cannabis (derivatives)	0.100	0.900	0.000
T40.0 Opium	0.100	0.900	0.000
Z29 Need for other prophylactic measures	0.098	0.902	0.000
T40.4 Other synthetic narcotics	0.097	0.903	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.096	0.903	0.000
T40.5 Cocaine	0.096	0.904	0.000
T40.2 Other opioids	0.095	0.905	0.000
T40.3 Methadone	0.095	0.905	0.000
T40.6 Other and unspecified narcotics	0.091	0.909	0.000
Z29.8 Other specified prophylactic measures	0.091	0.909	0.000
Z29.1 Prophylactic immunotherapy	0.086	0.914	0.000
Z29.0 Isolation	0.084	0.915	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.082	0.917	0.000
T47.0 Histamine H(2)-receptor antagonists	0.080	0.919	0.001
T45.5 Anticoagulants	0.077	0.922	0.001
Z29.9 Prophylactic measure, unspecified	0.070	0.929	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.062	0.937	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.059	0.940	0.000
T46.7 Peripheral vasodilators	0.059	0.940	0.000
T46.1 Calcium-channel blockers	0.059	0.941	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.058	0.941	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.055	0.945	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.054	0.945	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.053	0.946	0.000
H40 Glaucoma	0.048	0.952	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.046	0.954	0.000
H40.1 Primary open-angle glaucoma	0.044	0.956	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.040	0.959	0.000
H40.8 Other glaucoma	0.037	0.963	0.000
H40.5 Glaucoma secondary to other eye disorders	0.037	0.963	0.000
H40.6 Glaucoma secondary to drugs	0.035	0.965	0.000
H40.3 Glaucoma secondary to eye trauma	0.031	0.968	0.000
H40.4 Glaucoma secondary to eye inflammation	0.030	0.969	0.000
E83.4 Disorders of magnesium metabolism	0.000	0.973	0.027
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.027	0.973	0.000
H40-H42 Glaucoma	0.020	0.980	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.020	0.980	0.000
T42.2 Succinimides and oxazolidinediones	0.020	0.980	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.020	0.980	0.000
T42.0 Hydantoin derivatives	0.020	0.980	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.019	0.981	0.000
T42.3 Barbiturates	0.018	0.982	0.000
H40.0 Glaucoma suspect	0.017	0.983	0.000
E83 Disorders of mineral metabolism	0.000	0.984	0.016
H40.2 Primary angle-closure glaucoma	0.016	0.984	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.016	0.984	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.016	0.984	0.000
T42.1 Iminostilbenes	0.015	0.984	0.000
E83.3 Disorders of phosphorus metabolism	0.000	0.985	0.015
H42 Glaucoma in diseases classified elsewhere	0.015	0.985	0.000
E83.5 Disorders of calcium metabolism	0.000	0.985	0.015
S83.2 Tear of meniscus, current	0.013	0.987	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.988	0.012
E83.8 Other disorders of mineral metabolism	0.000	0.988	0.012
E83.2 Disorders of zinc metabolism	0.000	0.988	0.012
E83.0 Disorders of copper metabolism	0.000	0.988	0.012
Z28 Immunisation not carried out	0.012	0.988	0.000
Z25 Need for immunisation against other single viral diseases	0.012	0.988	0.000
Z23 Need for immunisation against single bacterial diseases	0.012	0.988	0.000
Z26 Need for immunisation against other single infectious diseases	0.011	0.988	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.011	0.988	0.000
Z24 Need for immunisation against certain single viral diseases	0.011	0.989	0.000
Z20 Contact with and exposure to communicable diseases	0.011	0.989	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.011	0.989	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.011	0.989	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.011	0.989	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.011	0.989	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.010	0.990	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.009	0.991	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.009	0.991	0.000
Z23.7 Need for immunisation against pertussis alone	0.009	0.991	0.000
Z23.6 Need for immunisation against diphtheria alone	0.009	0.991	0.000
Z23.5 Need for immunisation against tetanus alone	0.009	0.991	0.000
Z23.4 Need for immunisation against tularaemia	0.009	0.991	0.000
Z23.3 Need for immunisation against plague	0.009	0.991	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.009	0.991	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.009	0.991	0.000
Z23.0 Need for immunisation against cholera alone	0.009	0.991	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.009	0.991	0.000
Z25.1 Need for immunisation against influenza	0.009	0.991	0.000
Z25.0 Need for immunisation against mumps alone	0.009	0.991	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.009	0.991	0.000
Z28.8 Immunisation not carried out for other reasons	0.009	0.991	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.009	0.991	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.009	0.991	0.000
Z28.0 Immunisation not carried out because of contraindication	0.009	0.991	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.008	0.991	0.000
Z26.0 Need for immunisation against leishmaniasis	0.008	0.991	0.000
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.008	0.991	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.008	0.991	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.008	0.991	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.008	0.991	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.008	0.991	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.008	0.991	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.008	0.992	0.000
Z24.6 Need for immunisation against viral hepatitis	0.008	0.992	0.000
Z24.4 Need for immunisation against measles alone	0.008	0.992	0.000
Z24.3 Need for immunisation against yellow fever	0.008	0.992	0.000
Z24.2 Need for immunisation against rabies	0.008	0.992	0.000
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.008	0.992	0.000
Z24.0 Need for immunisation against poliomyelitis	0.008	0.992	0.000
S83.7 Injury to multiple structures of knee	0.008	0.992	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.008	0.992	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.008	0.992	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.008	0.992	0.000
Z20.4 Contact with and exposure to rubella	0.008	0.992	0.000
Z20.3 Contact with and exposure to rabies	0.008	0.992	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.008	0.992	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.008	0.992	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.008	0.992	0.000
Z20.1 Contact with and exposure to tuberculosis	0.008	0.992	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.008	0.992	0.000
T42.4 Benzodiazepines	0.008	0.992	0.000
S83.0 Dislocation of patella	0.008	0.992	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.008	0.992	0.000
Z24.5 Need for immunisation against rubella alone	0.007	0.992	0.000
N64.5 Other signs and symptoms in breast	0.008	0.992	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.007	0.992	0.000
O42 Premature rupture of membranes	0.007	0.993	0.000
S83.1 Dislocation of knee	0.007	0.993	0.000
I89.1 Lymphangitis	0.000	0.993	0.007
S83.3 Tear of articular cartilage of knee, current	0.007	0.993	0.000
Z22 Carrier of infectious disease	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.006	0.994	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.006	0.994	0.000
Z22.5 Carrier of viral hepatitis	0.006	0.994	0.000
O16 Unspecified maternal hypertension	0.006	0.994	0.000
D68.6 Other Thrombophilia	0.000	0.994	0.006
D68 Other coagulation defects	0.000	0.995	0.005
O42.9 Premature rupture of membranes, unspecified	0.005	0.995	0.000
Z22.9 Carrier of infectious disease, unspecified	0.005	0.995	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.005	0.995	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.005	0.995	0.000
Z22.2 Carrier of diphtheria	0.005	0.995	0.000
Z22.0 Carrier of typhoid	0.005	0.995	0.000
D68.5 Primary Thrombophilia	0.000	0.995	0.005
D68.2 Hereditary deficiency of other clotting factors	0.000	0.995	0.005
O42.2 Premature rupture of membranes, labour delayed by therapy	0.005	0.995	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.995	0.005
D68.4 Acquired coagulation factor deficiency	0.000	0.995	0.005
Q21.1 Atrial septal defect	0.000	0.995	0.005
D68.1 Hereditary factor XI deficiency	0.000	0.995	0.005
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.005	0.995	0.000
O40 Polyhydramnios	0.005	0.995	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.995	0.005
D68.8 Other specified coagulation defects	0.000	0.995	0.004
O41.0 Oligohydramnios	0.004	0.995	0.000
Z22.1 Carrier of other intestinal infectious diseases	0.004	0.996	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.004
Z22.8 Carrier of other infectious diseases	0.004	0.996	0.000
D68.0 Von Willebrand's disease	0.000	0.996	0.004
H61.2 Impacted cerumen	0.004	0.996	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.004	0.996	0.000
O44 Placenta praevia	0.004	0.996	0.000
O36.9 Maternal care for foetal problem, unspecified	0.004	0.996	0.000
O36 Maternal care for other known or suspected foetal problems	0.004	0.996	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.996	0.004
Q07.0 Arnold-Chiari syndrome	0.000	0.996	0.004
O41 Other disorders of amniotic fluid and membranes	0.004	0.996	0.000
O45 Premature separation of placenta [abruptio placentae]	0.004	0.996	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.004	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.004	0.996	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.004	0.996	0.000
O44.1 Placenta praevia with haemorrhage	0.004	0.996	0.000
M50.0 Cervical disk disorder with myelopathy	0.004	0.996	0.000
O36.8 Maternal care for other specified foetal problems	0.004	0.996	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.004	0.996	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.004	0.996	0.000
E83.1 Disorders of iron metabolism	0.000	0.996	0.004
O36.4 Maternal care for intra-uterine death	0.004	0.996	0.000
W19.2 School, other institution and public administrative area	0.000	0.996	0.004
O12.2 Gestational oedema with proteinuria	0.004	0.996	0.000
O45.9 Premature separation of placenta, unspecified	0.004	0.996	0.000
O12.1 Gestational proteinuria	0.004	0.996	0.000
X78.0 Home	0.004	0.996	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.004	0.996	0.000
R61.9 Hyperhidrosis, unspecified	0.000	0.996	0.004
S32.00 Fracture of lumbar vertebra (closed)	0.004	0.996	0.000
O31 Complications specific to multiple gestation	0.003	0.996	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.003	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.003	0.997	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.003	0.997	0.000
O36.1 Maternal care for other isoimmunisation	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
O44.0 Placenta praevia specified as without haemorrhage	0.003	0.997	0.000
H61 Other disorders of external ear	0.003	0.997	0.000
O12.0 Gestational oedema	0.003	0.997	0.000
O33 Maternal care for known or suspected disproportion	0.003	0.997	0.000
O34.4 Maternal care for other abnormalities of cervix	0.003	0.997	0.000
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.003	0.997	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.003	0.997	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.003	0.997	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.003	0.997	0.000
O36.2 Maternal care for hydrops foetalis	0.003	0.997	0.000
O45.8 Other premature separation of placenta	0.003	0.997	0.000
O45.0 Premature separation of placenta with coagulation defect	0.003	0.997	0.000
Q21 Congenital malformations of cardiac septa	0.000	0.997	0.003
O46.0 Antepartum haemorrhage with coagulation defect	0.003	0.997	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.003	0.997	0.000
C34.0 Main bronchus	0.000	0.997	0.003
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.997	0.003
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.003	0.997	0.000
O15 Eclampsia	0.003	0.997	0.000
O14.9 Preeclampsia, unspecified	0.003	0.997	0.000
H61.8 Other specified disorders of external ear	0.003	0.997	0.000
R50.0 Fever with chills	0.003	0.997	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.003	0.997	0.000
F12.1 Harmful use	0.000	0.997	0.003
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.003	0.997	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.003	0.997	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.997	0.003
O30 Multiple gestation	0.003	0.997	0.000
O41.1 Infection of amniotic sac and membranes	0.003	0.997	0.000
D03 Melanoma in situ	0.000	0.997	0.003
O34.0 Maternal care for congenital malformation of uterus	0.003	0.997	0.000
D68.9 Coagulation defect, unspecified	0.000	0.997	0.003
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.003	0.997	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.003	0.997	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.003	0.997	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.003	0.997	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.003	0.997	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
M79.79 Fibromyalgia (Site unspecified)	0.000	0.997	0.003
O31.0 Papyraceous foetus	0.003	0.997	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.003	0.997	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.003	0.997	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
G30.9 Alzheimer's disease, unspecified	0.003	0.997	0.000
Q21.3 Tetralogy of Fallot	0.000	0.997	0.003
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.997	0.003
Z96.8 Presence of other specified functional implants	0.000	0.997	0.003
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.003	0.997	0.000
X78 Intentional self-harm by sharp object	0.003	0.997	0.000
O33.8 Maternal care for disproportion of other origin	0.002	0.997	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.002	0.997	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.002	0.997	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.002	0.997	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.002	0.997	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.002	0.997	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.002	0.997	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.002	0.997	0.000
O43 Placental disorders	0.003	0.997	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.002	0.997	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.003	0.997	0.000
R23.2 Flushing	0.003	0.997	0.000
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.997	0.003
O14.2 HELLP syndrome	0.002	0.997	0.000
Q21.4 Aortopulmonary septal defect	0.000	0.997	0.002
Q21.2 Atrioventricular septal defect	0.000	0.997	0.002
O36.5 Maternal care for poor foetal growth	0.003	0.997	0.000
Q21.8 Other congenital malformations of cardiac septa	0.000	0.997	0.002
Q24.8 Other specified congenital malformations of heart	0.000	0.997	0.003
C02.1 Border of tongue	0.000	0.997	0.003
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.997	0.002
O34.3 Maternal care for cervical incompetence	0.002	0.997	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.997	0.000
D03.8 Melanoma in situ of other sites	0.000	0.997	0.002
H61.9 Disorder of external ear, unspecified	0.002	0.997	0.000
O31.8 Other complications specific to multiple gestation	0.002	0.997	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.002	0.997	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.003	0.997	0.000
C10.9 Oropharynx, unspecified	0.000	0.998	0.002
O15.9 Eclampsia, unspecified as to time period	0.002	0.998	0.000
O15.2 Eclampsia in the puerperium	0.002	0.998	0.000
O15.1 Eclampsia in labour	0.002	0.998	0.000
O15.0 Eclampsia in pregnancy	0.002	0.998	0.000
O30.1 Triplet pregnancy	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
J30-J39 Other diseases of upper respiratory tract	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.000	0.998	0.002
O48 Prolonged pregnancy	0.002	0.998	0.000
S62.61 Fracture of other finger (open)	0.002	0.998	0.000
J37.0 Chronic laryngitis	0.000	0.998	0.002
O30.9 Multiple gestation, unspecified	0.002	0.998	0.000
O30.8 Other multiple gestation	0.002	0.998	0.000
O30.2 Quadruplet pregnancy	0.002	0.998	0.000
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
J37 Chronic laryngitis and laryngotracheitis	0.000	0.998	0.002
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
O33.9 Maternal care for disproportion, unspecified	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.002	0.998	0.000
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
D03.9 Melanoma in situ, unspecified	0.000	0.998	0.002
D03.0 Melanoma in situ of lip	0.000	0.998	0.002
O32.4 Maternal care for high head at term	0.002	0.998	0.000
M16.7 Other secondary coxarthrosis	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.000	0.998	0.002
O32.9 Maternal care for malpresentation of foetus, unspecified	0.002	0.998	0.000
O43.9 Placental disorder, unspecified	0.002	0.998	0.000
Z22.3 Carrier of other specified bacterial diseases	0.002	0.998	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O14.1 Severe preeclampsia	0.002	0.998	0.000
R23.4 Changes in skin texture	0.002	0.998	0.000
X78.2 School, other institution and public administrative area	0.002	0.998	0.000
Q07 Other congenital malformations of nervous system	0.000	0.998	0.002
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
R23.3 Spontaneous ecchymoses	0.002	0.998	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
R23 Other skin changes	0.002	0.998	0.000
C02.9 Tongue, unspecified	0.000	0.998	0.002
O32.0 Maternal care for unstable lie	0.002	0.998	0.000
X78.9 Unspecified place	0.002	0.998	0.000
X78.8 Other specified place	0.002	0.998	0.000
X78.7 Farm	0.002	0.998	0.000
X78.6 Industrial and construction area	0.002	0.998	0.000
X78.5 Trade and service area	0.002	0.998	0.000
X78.4 Street and highway	0.002	0.998	0.000
X78.3 Sports and athletics area	0.002	0.998	0.000
X78.1 Residential institution	0.002	0.998	0.000
C34.3 Lower lobe, bronchus or lung	0.000	0.998	0.002
G93.1 Anoxic brain damage, not elsewhere classified	0.002	0.998	0.000
O43.2 Morbidly adherent placenta	0.002	0.998	0.000
O43.0 Placental transfusion syndromes	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.000	0.998	0.002
D03.4 Melanoma in situ of scalp and neck	0.000	0.998	0.002
C34.8 Overlapping lesion of bronchus and lung	0.000	0.998	0.002
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.000	0.998	0.002
C10 Malignant neoplasm of oropharynx	0.000	0.998	0.002
C34.2 Middle lobe, bronchus or lung	0.000	0.998	0.002
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
C02.4 Lingual tonsil	0.000	0.998	0.002
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
M79.70 Fibromyalgia (Multiple sites)	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
C34.9 Bronchus or lung, unspecified	0.000	0.998	0.002
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M00.94 Pyogenic arthritis, unspecified (Hand)	0.002	0.998	0.000
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.002	0.998	0.000
J37.1 Chronic laryngotracheitis	0.000	0.998	0.002
O34.8 Maternal care for other abnormalities of pelvic organs	0.002	0.998	0.000
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.002	0.998	0.000
M00.9 Pyogenic arthritis, unspecified	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.000	0.998	0.002
X62.9 Unspecified place	0.002	0.998	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
O32.6 Maternal care for compound presentation	0.002	0.998	0.000
C02.0 Dorsal surface of tongue	0.000	0.998	0.002
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.002	0.998	0.000
M00.99 Pyogenic arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.000	0.998	0.002
N80.3 Endometriosis of pelvic peritoneum	0.000	0.998	0.002
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.998	0.002
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
M79.7 Fibromyalgia	0.000	0.998	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.000	0.998	0.002
Q07.8 Other specified congenital malformations of nervous system	0.000	0.998	0.002
S32.0 Fracture of lumbar vertebra	0.002	0.998	0.000
R61 Hyperhidrosis	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.000	0.998	0.002
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.000	0.998	0.002
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.000	0.998	0.002
X78.99 Intentional self-harm by sharp object: Unspecified place: During unspecified activity	0.002	0.998	0.000
Q24.6 Congenital heart block	0.000	0.998	0.002
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations