TreeWAS – Variant ID: rs2349775

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G62.8 Other specified polyneuropathies	0.000	0.981	0.019
G61.8 Other inflammatory polyneuropathies	0.000	0.982	0.018
G61 Inflammatory polyneuropathy	0.000	0.983	0.017
J30.1 Allergic rhinitis due to pollen	0.000	0.983	0.017
G62 Other polyneuropathies	0.000	0.984	0.016
G61.0 Guillain-Barre syndrome	0.000	0.984	0.016
Z94.8 Other transplanted organ and tissue status	0.000	0.985	0.015
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.985	0.015
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.986	0.014
J30 Vasomotor and allergic rhinitis	0.000	0.987	0.013
E07.9 Disorder of thyroid, unspecified	0.000	0.987	0.013
G61.1 Serum neuropathy	0.000	0.987	0.013
J30.4 Allergic rhinitis, unspecified	0.000	0.988	0.012
G62.0 Drug-induced polyneuropathy	0.000	0.988	0.012
J30.3 Other allergic rhinitis	0.000	0.988	0.012
G62.2 Polyneuropathy due to other toxic agents	0.000	0.988	0.012
G62.1 Alcoholic polyneuropathy	0.000	0.988	0.012
G62.9 Polyneuropathy, unspecified	0.000	0.988	0.012
K76.9 Liver disease, unspecified	0.011	0.989	0.000
G64 Other disorders of peripheral nervous system	0.000	0.989	0.011
J30.2 Other seasonal allergic rhinitis	0.000	0.991	0.009
G60 Hereditary and idiopathic neuropathy	0.000	0.991	0.009
J30.0 Vasomotor rhinitis	0.000	0.992	0.008
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.992	0.008
E07 Other disorders of thyroid	0.000	0.992	0.008
F60.3 Emotionally unstable personality disorder	0.007	0.993	0.000
G60.3 Idiopathic progressive neuropathy	0.000	0.993	0.006
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.993	0.006
G60.1 Refsum's disease	0.000	0.993	0.006
G60.0 Hereditary motor and sensory neuropathy	0.000	0.994	0.006
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.994	0.006
I22.1 Subsequent myocardial infarction of inferior wall	0.006	0.994	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.994	0.006
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.994	0.006
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.994	0.006
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.994	0.006
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.994	0.006
G63.1 Polyneuropathy in neoplastic disease	0.000	0.994	0.006
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.994	0.006
J98.8 Other specified respiratory disorders	0.000	0.994	0.006
E07.1 Dyshormogenetic goitre	0.000	0.994	0.006
E07.0 Hypersecretion of calcitonin	0.000	0.994	0.006
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.994	0.005
E06.3 Autoimmune thyroiditis	0.000	0.994	0.006
E06 Thyroiditis	0.000	0.995	0.005
F10.0 Acute intoxication	0.000	0.995	0.005
G82.1 Spastic paraplegia	0.005	0.995	0.000
E00-E07 Disorders of thyroid gland	0.000	0.995	0.005
E04.2 Non-toxic multinodular goitre	0.000	0.995	0.005
G82.2 Paraplegia, unspecified	0.005	0.995	0.000
E06.5 Other chronic thyroiditis	0.000	0.995	0.005
E07.8 Other specified disorders of thyroid	0.000	0.995	0.004
G82 Paraplegia and tetraplegia	0.005	0.995	0.000
E04 Other non-toxic goitre	0.000	0.996	0.004
F60 Specific personality disorders	0.004	0.996	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.996	0.004
E06.4 Drug-induced thyroiditis	0.000	0.996	0.004
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.996	0.004
E06.0 Acute thyroiditis	0.000	0.996	0.004
E06.9 Thyroiditis, unspecified	0.000	0.996	0.004
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.996	0.004
E00 Congenital iodine-deficiency syndrome	0.000	0.996	0.004
H40.2 Primary angle-closure glaucoma	0.000	0.996	0.004
G82.5 Tetraplegia, unspecified	0.004	0.996	0.000
F60.0 Paranoid personality disorder	0.004	0.996	0.000
N48.6 Balanitis xerotica obliterans	0.000	0.996	0.004
K42.0 Umbilical hernia with obstruction, without gangrene	0.004	0.996	0.000
F60.8 Other specific personality disorders	0.004	0.996	0.000
F60.4 Histrionic personality disorder	0.004	0.996	0.000
F60.7 Dependent personality disorder	0.004	0.996	0.000
S71.1 Open wound of thigh	0.004	0.996	0.000
E06.1 Subacute thyroiditis	0.000	0.996	0.003
E03 Other hypothyroidism	0.000	0.996	0.004
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
G82.4 Spastic tetraplegia	0.004	0.996	0.000
O30.0 Twin pregnancy	0.004	0.996	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.996	0.004
F60.2 Dissocial personality disorder	0.003	0.996	0.000
G82.3 Flaccid tetraplegia	0.003	0.996	0.000
G82.0 Flaccid paraplegia	0.003	0.996	0.000
E04.8 Other specified non-toxic goitre	0.000	0.997	0.003
F60.1 Schizoid personality disorder	0.003	0.997	0.000
F60.5 Anankastic personality disorder	0.003	0.997	0.000
E03.8 Other specified hypothyroidism	0.000	0.997	0.003
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.997	0.003
E04.1 Non-toxic single thyroid nodule	0.000	0.997	0.003
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.997	0.003
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.997	0.003
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.997	0.003
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.997	0.003
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.997	0.003
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.997	0.003
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.997	0.003
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.997	0.003
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.997	0.003
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.997	0.003
E04.0 Non-toxic diffuse goitre	0.000	0.997	0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.997	0.003
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.997	0.003
F60.6 Anxious [avoidant] personality disorder	0.003	0.997	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.003	0.997	0.000
E03.5 Myxoedema coma	0.000	0.997	0.003
E03.4 Atrophy of thyroid (acquired)	0.000	0.997	0.003
E03.3 Postinfectious hypothyroidism	0.000	0.997	0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.997	0.003
Z89.5 Acquired absence of leg at or below knee	0.000	0.997	0.003
E05.5 Thyroid crisis or storm	0.000	0.997	0.003
E05.4 Thyrotoxicosis factitia	0.000	0.997	0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.997	0.003
I22 Subsequent myocardial infarction	0.003	0.997	0.000
E05.8 Other thyrotoxicosis	0.000	0.997	0.003
Z99.3 Dependence on wheelchair	0.003	0.997	0.000
E03.1 Congenital hypothyroidism without goitre	0.000	0.997	0.002
E05.9 Thyrotoxicosis, unspecified	0.000	0.997	0.003
G57.8 Other mononeuropathies of lower limb	0.000	0.998	0.002
E04.9 Non-toxic goitre, unspecified	0.000	0.998	0.002
I22.8 Subsequent myocardial infarction of other sites	0.002	0.998	0.000
L60.0 Ingrowing nail	0.000	0.998	0.002
L84 Corns and callosities	0.002	0.998	0.000
I22.0 Subsequent myocardial infarction of anterior wall	0.002	0.998	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
Z89.6 Acquired absence of leg above knee	0.000	0.998	0.002
F60-F69 Disorders of adult personality and behaviour	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
W55.0 Home	0.000	0.998	0.002
E10.1 With ketoacidosis	0.002	0.998	0.000
G57.6 Lesion of plantar nerve	0.000	0.998	0.002
W25.9 Unspecified place	0.000	0.998	0.002
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.998	0.002
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
G30.9 Alzheimer's disease, unspecified	0.002	0.998	0.000
S42.30 Fracture of shaft of humerus (closed)	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
S41.0 Open wound of shoulder	0.002	0.998	0.000
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
G57.1 Meralgia paraesthetica	0.000	0.998	0.002
H54.4 Blindness, one eye	0.002	0.998	0.000
Z89 Acquired absence of limb	0.000	0.998	0.002
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.998	0.002
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.002	0.998	0.000
G57 Mononeuropathies of lower limb	0.000	0.998	0.002
G57.0 Lesion of sciatic nerve	0.000	0.998	0.002
O72.0 Third-stage haemorrhage	0.002	0.998	0.000
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
F61 Mixed and other personality disorders	0.002	0.998	0.000
O30 Multiple gestation	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.002	0.998	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
O30.1 Triplet pregnancy	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
L89.3 Stage IV decubitus ulcer	0.002	0.998	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
S49.9 Unspecified injury of shoulder and upper arm	0.002	0.998	0.000
F64 Gender identity disorders	0.002	0.998	0.000
Z89.9 Acquired absence of limb, unspecified	0.000	0.998	0.002
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.998	0.000
G30.8 Other Alzheimer's disease	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
G30.0 Alzheimer's disease with early onset	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
G30 Alzheimer's disease	0.002	0.998	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.998	0.002
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
I22.9 Subsequent myocardial infarction of unspecified site	0.002	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
Q21.0 Ventricular septal defect	0.002	0.998	0.000
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.998	0.002
Z89.1 Acquired absence of hand and wrist	0.000	0.998	0.002
U51.0 Not Previously admitted to a psyciatric hospital	0.000	0.998	0.002
W55.8 Other specified place	0.000	0.998	0.002
S40-S49 Injuries to the shoulder and upper arm	0.002	0.998	0.000
S42.3 Fracture of shaft of humerus	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.998	0.002
C38.4 Pleura	0.000	0.998	0.002
G57.4 Lesion of medial popliteal nerve	0.000	0.998	0.002
G57.2 Lesion of femoral nerve	0.000	0.998	0.002
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.998	0.002
D47.1 Chronic myeloproliferative disease	0.000	0.998	0.002
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.002	0.998	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.001	0.998	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.001	0.998	0.000
S49.8 Other specified injuries of shoulder and upper arm	0.002	0.998	0.000
Z90.2 Acquired absence of lung [part of]	0.000	0.998	0.002
L73.8 Other specified follicular disorders	0.000	0.998	0.002
O30.9 Multiple gestation, unspecified	0.002	0.998	0.000
O30.8 Other multiple gestation	0.002	0.998	0.000
O30.2 Quadruplet pregnancy	0.002	0.998	0.000
D25.9 Leiomyoma of uterus, unspecified	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
F63.9 Habit and impulse disorder, unspecified	0.001	0.998	0.000
F63.8 Other habit and impulse disorders	0.001	0.998	0.000
F63.3 Trichotillomania	0.001	0.998	0.000
F63.2 Pathological stealing [kleptomania]	0.001	0.998	0.000
F63.1 Pathological fire-setting [pyromania]	0.001	0.998	0.000
F63.0 Pathological gambling	0.001	0.998	0.000
F65.9 Disorder of sexual preference, unspecified	0.001	0.998	0.000
F65.8 Other disorders of sexual preference	0.001	0.998	0.000
F65.6 Multiple disorders of sexual preference	0.001	0.998	0.000
F65.5 Sadomasochism	0.001	0.998	0.000
F65.4 Paedophilia	0.001	0.998	0.000
F65.3 Voyeurism	0.001	0.998	0.000
F65.2 Exhibitionism	0.001	0.998	0.000
F65.1 Fetishistic transvestism	0.001	0.998	0.000
F65.0 Fetishism	0.001	0.998	0.000
F66.9 Psychosexual development disorder, unspecified	0.001	0.998	0.000
F66.8 Other psychosexual development disorders	0.001	0.998	0.000
F66.2 Sexual relationship disorder	0.001	0.998	0.000
F66.1 Egodystonic sexual orientation	0.001	0.998	0.000
F66.0 Sexual maturation disorder	0.001	0.998	0.000
W55 Bitten or struck by other mammals	0.000	0.998	0.002
G83.4 Cauda equina syndrome	0.002	0.998	0.000
J98.2 Interstitial emphysema	0.000	0.998	0.002
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
S43.2 Dislocation of sternoclavicular joint	0.001	0.998	0.000
F64.9 Gender identity disorder, unspecified	0.001	0.998	0.000
F64.8 Other gender identity disorders	0.001	0.998	0.000
F64.2 Gender identity disorder of childhood	0.001	0.998	0.000
F64.1 Dual-role transvestism	0.001	0.998	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
R57.2 Septic shock	0.002	0.998	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.001	0.998	0.000
S44 Injury of nerves at shoulder and upper arm level	0.002	0.998	0.000
F62.8 Other enduring personality changes	0.001	0.998	0.000
F62.1 Enduring personality change after psychiatric illness	0.001	0.998	0.000
F62.0 Enduring personality change after catastrophic experience	0.001	0.998	0.000
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.998	0.001
S46 Injury of muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.001	0.998	0.000
F64.0 Transsexualism	0.001	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.998	0.001
G30.1 Alzheimer's disease with late onset	0.001	0.998	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.000	0.998	0.001
G57.3 Lesion of lateral popliteal nerve	0.000	0.998	0.001
M22.8 Other disorders of patella	0.000	0.998	0.002
S41.7 Multiple open wounds of shoulder and upper arm	0.001	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.001	0.998	0.000
W55.7 Farm	0.000	0.998	0.001
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.998	0.002
R25.2 Cramp and spasm	0.002	0.998	0.000
S44.2 Injury of radial nerve at upper arm level	0.001	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
S48 Traumatic amputation of shoulder and upper arm	0.001	0.998	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.001	0.998	0.000
S47 Crushing injury of shoulder and upper arm	0.001	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.001	0.998	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.001	0.998	0.000
F62.9 Enduring personality change, unspecified	0.001	0.998	0.000
G57.5 Tarsal tunnel syndrome	0.000	0.998	0.001
N42.8 Other specified disorders of prostate	0.002	0.998	0.000
R60.9 Oedema, unspecified	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.001	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.999	0.001
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.999	0.001
S40 Superficial injury of shoulder and upper arm	0.001	0.999	0.000
S71 Open wound of hip and thigh	0.001	0.999	0.000
W55.9 Unspecified place	0.000	0.999	0.001
W55.5 Trade and service area	0.000	0.999	0.001
W55.6 Industrial and construction area	0.000	0.999	0.001
W55.3 Sports and athletics area	0.000	0.999	0.001
W55.2 School, other institution and public administrative area	0.000	0.999	0.001
W55.1 Residential institution	0.000	0.999	0.001
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.999	0.001
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.999	0.001
L89.2 Stage III decubitus ulcer	0.001	0.999	0.000
O21.0 Mild hyperemesis gravidarum	0.000	0.999	0.001
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.001	0.999	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.001	0.999	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.001	0.999	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.001	0.999	0.000
S44.4 Injury of musculocutaneous nerve	0.001	0.999	0.000
S44.3 Injury of axillary nerve	0.001	0.999	0.000
S44.1 Injury of median nerve at upper arm level	0.001	0.999	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.001	0.999	0.000
W55.4 Street and highway	0.000	0.999	0.001
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.999	0.001
G83.3 Monoplegia, unspecified	0.001	0.999	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.001	0.999	0.000
S46.3 Injury of muscle and tendon of triceps	0.001	0.999	0.000
G83 Other paralytic syndromes	0.001	0.999	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.001	0.999	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.999	0.001
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.999	0.001
S40.8 Other superficial injuries of shoulder and upper arm	0.001	0.999	0.000
L60.3 Nail dystrophy	0.000	0.999	0.001
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.001	0.999	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.001	0.999	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.001	0.999	0.000
S45.2 Injury of axillary or brachial vein	0.001	0.999	0.000
S45.1 Injury of brachial artery	0.001	0.999	0.000
S45.0 Injury of axillary artery	0.001	0.999	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.001	0.999	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.001	0.999	0.000
S48.0 Traumatic amputation at shoulder joint	0.001	0.999	0.000
V23.5 Passenger injured in traffic accident	0.001	0.999	0.000
G83.1 Monoplegia of lower limb	0.001	0.999	0.000
O82.0 Delivery by elective Caesarean section	0.001	0.999	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
C80.9 Malignant neoplasm, unspecified	0.001	0.999	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.999	0.001
S40.7 Multiple superficial injuries of shoulder and upper arm	0.001	0.999	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.001	0.999	0.000
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.001	0.999	0.000
S42 Fracture of shoulder and upper arm	0.001	0.999	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.999	0.001
W55.58 Bitten or struck by other mammals; Trade and service area;While engaged in other specified activities	0.000	0.999	0.001
W55.99 Bitten or struck by other mammals: Unspecified place: During unspecified activity	0.000	0.999	0.001
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.999	0.001
L89.9 Decubitus ulcer and pressure area, unspecified	0.001	0.999	0.000
V23.0 Driver injured in nontraffic accident	0.001	0.999	0.000
M79.61 Pain in limb (Shoulder region)	0.000	0.999	0.001
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.999	0.001
S62.50 Fracture of thumb (closed)	0.001	0.999	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.001	0.999	0.000
S71.7 Multiple open wounds of of hip and thigh	0.001	0.999	0.000
X49.9 Unspecified place	0.000	0.999	0.001
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.999	0.001
M25.56 Pain in joint (Lower leg)	0.000	0.999	0.001
S42.80 Fracture of other parts of shoulder and upper arm (closed)	0.001	0.999	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.001	0.999	0.000
J98 Other respiratory disorders	0.000	0.999	0.001
L89 Decubitus ulcer	0.001	0.999	0.000
D26.0 Cervix uteri	0.000	0.999	0.001
G83.5 Locked-in syndrome	0.001	0.999	0.000
G83.0 Diplegia of upper limbs	0.001	0.999	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.001	0.999	0.000
S42.9 Fracture of shoulder girdle, part unspecified	0.001	0.999	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.000	0.999	0.001
V23.9 Unspecified motorcycle rider injured in traffic accident	0.001	0.999	0.000
V23.3 Person injured while boarding or alighting	0.001	0.999	0.000
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.001	0.999	0.000
V23.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
O82 Single delivery by Caesarean section	0.001	0.999	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.001	0.999	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.001	0.999	0.000
M43.09 Spondylolysis (Site unspecified)	0.000	0.999	0.001
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.001	0.999	0.000
R01.1 Cardiac murmur, unspecified	0.001	0.999	0.000
Z36.9 Antenatal screening, unspecified	0.001	0.999	0.000
Z74.1 Need for assistance with personal care	0.000	0.999	0.001
E28.2 Polycystic ovarian syndrome	0.000	0.999	0.001
E87.2 Acidosis	0.001	0.999	0.000
G83.8 Other specified paralytic syndromes	0.001	0.999	0.000
K12.3 Oral mucositis (ulcerative)	0.000	0.999	0.001
S40.0 Contusion of shoulder and upper arm	0.001	0.999	0.000
S42.81 Fracture of other parts of shoulder and upper arm (open)	0.001	0.999	0.000
S42.90 Fracture of shoulder girdle, part unspecified (closed)	0.001	0.999	0.000
O03.9 Complete or unspecified, without complication	0.001	0.999	0.000
O82.9 Delivery by Caesarean section, unspecified	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.001	0.999	0.000
T91 Sequelae of injuries of neck and trunk	0.001	0.999	0.000
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.001	0.999	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.001	0.999	0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.001	0.999	0.000
J98.3 Compensatory emphysema	0.000	0.999	0.001
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.001	0.999	0.000
T87.6 Other and unspecified complications of amputation stump	0.000	0.999	0.001
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
S42.91 Fracture of shoulder girdle, part unspecified (open)	0.001	0.999	0.000
E23.0 Hypopituitarism	0.000	0.999	0.001
G83.9 Paralytic syndrome, unspecified	0.001	0.999	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.999	0.001
O82.8 Other single delivery by Caesarean section	0.001	0.999	0.000
O82.2 Delivery by Caesarean hysterectomy	0.001	0.999	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.001	0.999	0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.999	0.001
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.999	0.001
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
S02.10 Fracture of base of skull (closed)	0.001	0.999	0.000
L72.1 Trichilemmal cyst	0.000	0.999	0.001
S71.0 Open wound of hip	0.001	0.999	0.000
W10.8 Other specified place	0.000	0.999	0.001
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
I86.2 Pelvic varices	0.001	0.999	0.000
J20.9 Acute bronchitis, unspecified	0.000	0.999	0.001
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.999	0.001
T91.2 Sequelae of other fracture of thorax and pelvis	0.001	0.999	0.000
E03.9 Hypothyroidism, unspecified	0.000	0.999	0.001
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.001	0.999	0.000
J04.0 Acute laryngitis	0.001	0.999	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.001	0.999	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.001	0.999	0.000
T45.0 Antiallergic and antiemetic drugs	0.001	0.999	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.001	0.999	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.001	0.999	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.001	0.999	0.000
L60 Nail disorders	0.000	0.999	0.001
O72 Postpartum haemorrhage	0.001	0.999	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
C44.7 Skin of lower limb, including hip	0.001	0.999	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.999	0.001
J95.4 Mendelson's syndrome	0.000	0.999	0.001
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.999	0.001
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.999	0.001
Q21.8 Other congenital malformations of cardiac septa	0.001	0.999	0.000
T11.1 Open wound of upper limb, level unspecified	0.000	0.999	0.001
Y85.0 Sequelae of motor-vehicle accident	0.001	0.999	0.000
Z88.2 Personal history of allergy to sulphonamides	0.000	0.999	0.001
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.999	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.999	0.001
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.001	0.999	0.000
K02.8 Other dental caries	0.001	0.999	0.000
I86.3 Vulval varices	0.001	0.999	0.000
J95.5 Postprocedural subglottic stenosis	0.000	0.999	0.001
L60.5 Yellow nail syndrome	0.000	0.999	0.001
L60.4 Beau's lines	0.000	0.999	0.001
O12.0 Gestational oedema	0.001	0.999	0.000
O72.3 Postpartum coagulation defects	0.001	0.999	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.001	0.999	0.000
D66 Hereditary factor VIII deficiency	0.001	0.999	0.000
W25 Contact with sharp glass	0.000	0.999	0.001
M43.06 Spondylolysis (Lumbar region)	0.000	0.999	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.001	0.999	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.000	0.999	0.001
T09.9 Unspecified injury of trunk, level unspecified	0.000	0.999	0.001
T09.3 Injury of spinal cord, level unspecified	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.000	0.999	0.001
D68.6 Other Thrombophilia	0.001	0.999	0.000
H11.1 Conjunctival degenerations and deposits	0.001	0.999	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.001	0.999	0.000
K81.9 Cholecystitis, unspecified	0.001	0.999	0.000
L60.1 Onycholysis	0.000	0.999	0.001
M41.9 Scoliosis, unspecified	0.000	0.999	0.001
O72.1 Other immediate postpartum haemorrhage	0.001	0.999	0.000
W25.6 Industrial and construction area	0.000	0.999	0.001
W25.5 Trade and service area	0.000	0.999	0.001
W25.1 Residential institution	0.000	0.999	0.001
W25.0 Home	0.000	0.999	0.001
W25.7 Farm	0.000	0.999	0.001
W25.4 Street and highway	0.000	0.999	0.001
W25.3 Sports and athletics area	0.000	0.999	0.001
Z80.6 Family history of leukaemia	0.000	0.999	0.001
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.999	0.001
T11 Other injuries of upper limb, level unspecified	0.000	0.999	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.999	0.001
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
S72.10 Pertrochanteric fracture (closed)	0.001	0.999	0.000
D47.2 Monoclonal gammopathy	0.000	0.999	0.001
D68.8 Other specified coagulation defects	0.001	0.999	0.000
D69.5 Secondary thrombocytopenia	0.001	0.999	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.999	0.001
T11.9 Unspecified injury of upper limb, level unspecified	0.000	0.999	0.001
T11.8 Other specified injuries of upper limb, level unspecified	0.000	0.999	0.001
T11.6 Traumatic amputation of upper limb, level unspecified	0.000	0.999	0.001
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.000	0.999	0.001
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.000	0.999	0.001
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.000	0.999	0.001
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.000	0.999	0.001
W25.2 School, other institution and public administrative area	0.000	0.999	0.001
Z54.0 Convalescence following surgery	0.001	0.999	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
W25.09 Contact with sharp glass; Home; During unspecified activity	0.000	0.999	0.001
W25.03 Contact with sharp glass; Home; While engaged in other types of work	0.000	0.999	0.001
W25.18 Contact with sharp glass; Residential institution;While engaged in other specified activities	0.000	0.999	0.001
W25.52 Contact with sharp glass; Trade and service area;While working for income	0.000	0.999	0.001
W25.62 Contact with sharp glass; Industrial and construction area ;While working for income	0.000	0.999	0.001
D83.9 Common variable immunodeficiency, unspecified	0.000	0.999	0.001
G53.0 Postzoster neuralgia	0.000	0.999	0.001
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.999	0.001
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.999	0.001
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.999	0.001
W25.8 Other specified place	0.000	0.999	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations