TreeWAS – Variant ID: rs2388436

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.414	0.586	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.408	0.592	0.000
H72 Perforation of tympanic membrane	0.312	0.688	0.000
H72.0 Central perforation of tympanic membrane	0.295	0.705	0.000
H72.2 Other marginal perforations of tympanic membrane	0.232	0.768	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.224	0.776	0.000
H72.1 Attic perforation of tympanic membrane	0.212	0.787	0.000
H65-H75 Diseases of middle ear and mastoid	0.170	0.830	0.000
H66 Suppurative and unspecified otitis media	0.146	0.854	0.000
H69 Other disorders of Eustachian tube	0.145	0.855	0.000
H73 Other disorders of tympanic membrane	0.139	0.861	0.000
H69.9 Eustachian tube disorder, unspecified	0.136	0.864	0.000
H74 Other disorders of middle ear and mastoid	0.133	0.867	0.000
H66.3 Other chronic suppurative otitis media	0.129	0.871	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.122	0.878	0.000
H67 Otitis media in diseases classified elsewhere	0.122	0.878	0.000
H74.0 Tympanosclerosis	0.119	0.881	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.117	0.883	0.000
H66.4 Suppurative otitis media, unspecified	0.114	0.886	0.000
H68 Eustachian salpingitis and obstruction	0.112	0.888	0.000
H73.1 Chronic myringitis	0.111	0.889	0.000
H73.8 Other specified disorders of tympanic membrane	0.108	0.892	0.000
H74.4 Polyp of middle ear	0.108	0.892	0.000
H73.0 Acute myringitis	0.106	0.894	0.000
H69.0 Patulous Eustachian tube	0.104	0.896	0.000
H72.8 Other perforations of tympanic membrane	0.102	0.898	0.001
H66.0 Acute suppurative otitis media	0.100	0.899	0.000
H66.9 Otitis media, unspecified	0.100	0.900	0.000
H71 Cholesteatoma of middle ear	0.098	0.902	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.098	0.902	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.098	0.902	0.000
H65 Nonsuppurative otitis media	0.097	0.903	0.000
H74.1 Adhesive middle ear disease	0.092	0.908	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.091	0.909	0.000
H65.3 Chronic mucoid otitis media	0.091	0.909	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.087	0.912	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.087	0.912	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.087	0.912	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.087	0.912	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.087	0.912	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.086	0.914	0.000
H68.0 Eustachian salpingitis	0.080	0.919	0.000
H70 Mastoiditis and related conditions	0.079	0.920	0.000
H65.1 Other acute nonsuppurative otitis media	0.071	0.929	0.000
H68.1 Obstruction of Eustachian tube	0.071	0.929	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.069	0.931	0.000
H69.8 Other specified disorders of Eustachian tube	0.068	0.932	0.000
Z96.0 Presence of urogenital implants	0.065	0.935	0.000
H65.4 Other chronic nonsuppurative otitis media	0.063	0.937	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.062	0.937	0.000
H70.2 Petrositis	0.057	0.943	0.000
H70.8 Other mastoiditis and related conditions	0.056	0.944	0.000
H65.0 Acute serous otitis media	0.054	0.946	0.000
H65.2 Chronic serous otitis media	0.053	0.946	0.000
H70.9 Mastoiditis, unspecified	0.050	0.950	0.000
H70.0 Acute mastoiditis	0.049	0.951	0.000
H70.1 Chronic mastoiditis	0.045	0.954	0.000
D05 Carcinoma in situ of breast	0.028	0.972	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.025	0.975	0.000
D05.7 Other carcinoma in situ of breast	0.022	0.978	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.980	0.020
K51.2 Ulcerative (chronic) proctitis	0.000	0.980	0.020
K51 Ulcerative colitis	0.000	0.981	0.019
K51.4 Pseudopolyposis of colon	0.000	0.982	0.018
D73.0 Hyposplenism	0.017	0.983	0.000
U80.1 Methicillin resistant agent	0.016	0.984	0.000
Chapter VIII Diseases of the ear and mastoid process	0.015	0.985	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.985	0.015
K51.5 Mucosal proctocolitis	0.000	0.985	0.015
K51.8 Other ulcerative colitis	0.000	0.985	0.015
J84.9 Interstitial pulmonary disease, unspecified	0.014	0.986	0.000
J84 Other interstitial pulmonary diseases	0.012	0.988	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.988	0.012
M79.65 Pain in limb (Pelvic region and thigh)	0.012	0.988	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.012	0.988	0.000
D73 Diseases of spleen	0.011	0.989	0.000
J84.8 Other specified interstitial pulmonary diseases	0.011	0.989	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.990	0.010
D73.3 Abscess of spleen	0.010	0.990	0.000
J84.0 Alveolar and parietoalveolar conditions	0.009	0.991	0.000
D73.4 Cyst of spleen	0.009	0.991	0.000
D73.1 Hypersplenism	0.009	0.991	0.000
D73.9 Disease of spleen, unspecified	0.008	0.992	0.000
H60-H62 Diseases of external ear	0.008	0.992	0.000
D73.2 Chronic congestive splenomegaly	0.008	0.992	0.000
H90-H95 Other disorders of ear	0.008	0.992	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.008	0.992	0.000
D05.0 Lobular carcinoma in situ	0.007	0.992	0.001
D73.8 Other diseases of spleen	0.007	0.993	0.000
H95.1 Other disorders following mastoidectomy	0.007	0.993	0.000
D73.5 Infarction of spleen	0.007	0.993	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.993	0.007
H95.8 Other postprocedural disorders of ear and mastoid process	0.007	0.993	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.007	0.993	0.000
L40.9 Psoriasis, unspecified	0.006	0.994	0.000
D05.1 Intraductal carcinoma in situ	0.006	0.994	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.006	0.994	0.000
H92.1 Otorrhoea	0.006	0.994	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.006	0.994	0.000
G20 Parkinson's disease	0.006	0.994	0.000
H92 Otalgia and effusion of ear	0.006	0.994	0.000
H60 Otitis externa	0.006	0.994	0.000
H60.1 Cellulitis of external ear	0.006	0.994	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.005	0.994	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.005	0.994	0.000
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.006	0.994	0.000
L40 Psoriasis	0.005	0.995	0.000
H60.0 Abscess of external ear	0.005	0.995	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.995	0.005
H62.8 Other disorders of external ear in diseases classified elsewhere	0.005	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.005	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H62.2 Otitis externa in mycoses	0.005	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.005	0.995	0.000
L40.8 Other psoriasis	0.005	0.995	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.005	0.995	0.000
L40.5 Arthropathic psoriasis	0.005	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.004	0.995	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
K11.2 Sialoadenitis	0.000	0.995	0.005
L40.4 Guttate psoriasis	0.005	0.995	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.005	0.995	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.005	0.995	0.000
H60.8 Other otitis externa	0.004	0.995	0.000
I34.1 Mitral (valve) prolapse	0.000	0.996	0.004
L40.1 Generalised pustular psoriasis	0.004	0.996	0.000
T92.1 Sequelae of fracture of arm	0.000	0.996	0.004
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H60.3 Other infective otitis externa	0.004	0.996	0.000
L40.0 Psoriasis vulgaris	0.004	0.996	0.000
H60.2 Malignant otitis externa	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
H60.5 Acute otitis externa, non-infective	0.004	0.996	0.000
L40.2 Acrodermatitis continua	0.004	0.996	0.000
R02 Gangrene, not elsewhere classified	0.000	0.996	0.004
H92.2 Otorrhagia	0.004	0.996	0.000
K45 Other abdominal hernia	0.000	0.996	0.004
F01.9 Vascular dementia, unspecified	0.004	0.996	0.000
G61.0 Guillain-Barre syndrome	0.004	0.996	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.996	0.004
C02.9 Tongue, unspecified	0.004	0.996	0.000
H93.8 Other specified disorders of ear	0.004	0.996	0.000
H93.3 Disorders of acoustic nerve	0.004	0.996	0.000
L40.3 Pustulosis palmaris et plantaris	0.003	0.996	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.000	0.996	0.004
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.996	0.000
H90.0 Conductive hearing loss, bilateral	0.004	0.996	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.004	0.996	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
H90.5 Sensorineural hearing loss, unspecified	0.003	0.997	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.997	0.003
M41.99 Scoliosis, unspecified (Site unspecified)	0.000	0.997	0.003
H93.9 Disorder of ear, unspecified	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.003	0.997	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.997	0.003
K45.1 Other specified abdominal hernia with gangrene	0.000	0.997	0.003
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
H50.1 Divergent concomitant strabismus	0.000	0.997	0.003
C65 Malignant neoplasm of renal pelvis	0.003	0.997	0.000
H91 Other hearing loss	0.003	0.997	0.000
R52.2 Other chronic pain	0.003	0.997	0.000
K70 Alcoholic liver disease	0.000	0.997	0.003
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.003	0.997	0.000
M41.9 Scoliosis, unspecified	0.000	0.997	0.003
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
K70.1 Alcoholic hepatitis	0.000	0.997	0.003
M66.06 Rupture of popliteal cyst-Lower leg	0.003	0.997	0.000
C64-C68 Malignant neoplasms of urinary tract	0.003	0.997	0.000
H80-H83 Diseases of inner ear	0.003	0.997	0.000
K70.4 Alcoholic hepatic failure	0.000	0.997	0.003
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
R29.6 Tendency to fall, not elsewhere classified	0.003	0.997	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
H61 Other disorders of external ear	0.002	0.998	0.000
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
Q66.8 Other congenital deformities of feet	0.000	0.998	0.002
L98.4 Chronic ulcer of skin, not elsewhere classified	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
G24.9 Dystonia, unspecified	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.998	0.000
G24 Dystonia	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.002	0.998	0.000
G24.8 Other dystonia	0.002	0.998	0.000
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
H91.8 Other specified hearing loss	0.002	0.998	0.000
H91.1 Presbycusis	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.998	0.002
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
F01 Vascular dementia	0.002	0.998	0.000
H50 Other strabismus	0.000	0.998	0.002
G20-G26 Extrapyramidal and movement disorders	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.000	0.998	0.002
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.002	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
D37.0 Lip, oral cavity and pharynx	0.000	0.998	0.002
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.002	0.998	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.002	0.998	0.000
C32.0 Glottis	0.000	0.998	0.002
J80 Adult respiratory distress syndrome	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.000	0.998	0.002
M41.92 Scoliosis, unspecified (Cervical region)	0.000	0.998	0.002
F01.1 Multi-infarct dementia	0.002	0.998	0.000
H50.5 Heterophoria	0.000	0.998	0.002
Q66.0 Talipes equinovarus	0.000	0.998	0.002
G61.1 Serum neuropathy	0.002	0.998	0.000
H50.2 Vertical strabismus	0.000	0.998	0.002
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.998	0.002
A46 Erysipelas	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.002
H50.4 Other and unspecified heterotropia	0.000	0.998	0.002
S13.4 Sprain and strain of cervical spine	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.000	0.998	0.002
D76.3 Other histiocytosis syndromes	0.002	0.998	0.000
H50.8 Other specified strabismus	0.000	0.998	0.002
Q66.9 Congenital deformity of feet, unspecified	0.000	0.998	0.002
C02.2 Ventral surface of tongue	0.002	0.998	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.998	0.002
D76.2 Haemophagocytic syndrome, infection-associated	0.002	0.998	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.002	0.998	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.002	0.998	0.000
G24.4 Idiopathic orofacial dystonia	0.002	0.998	0.000
G24.2 Idiopathic nonfamilial dystonia	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.000	0.998	0.002
S52.6 Fracture of lower end of both ulna and radius	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
H61.3 Acquired stenosis of external ear canal	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
W49.9 Unspecified place	0.000	0.998	0.002
D74.9 Methaemoglobinaemia, unspecified	0.002	0.998	0.000
D74.8 Other methaemoglobinaemias	0.002	0.998	0.000
D74.0 Congenital methaemoglobinaemia	0.002	0.998	0.000
G24.1 Idiopathic familial dystonia	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.002	0.998	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.998	0.002
F01.8 Other vascular dementia	0.002	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.998	0.000
F01.2 Subcortical vascular dementia	0.002	0.998	0.000
F01.0 Vascular dementia of acute onset	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.998	0.002
C49.3 Connective and soft tissue of thorax	0.000	0.998	0.002
C51.9 Vulva, unspecified	0.000	0.998	0.002
H50.6 Mechanical strabismus	0.000	0.998	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.000	0.998	0.002
Q61 Cystic kidney disease	0.000	0.998	0.002
C49.1 Connective and soft tissue of upper limb, including shoulder	0.000	0.998	0.002
H50.3 Intermittent heterotropia	0.000	0.998	0.002
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
G24.0 Drug-induced dystonia	0.002	0.998	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.998	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.002	0.998	0.000
M66.08 Rupture of popliteal cyst-Other	0.002	0.998	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.002	0.998	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.002	0.998	0.000
M66.04 Rupture of popliteal cyst-Hand	0.002	0.998	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.002	0.998	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.002	0.998	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.002	0.998	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.002	0.998	0.000
C02.8 Overlapping lesion of tongue	0.002	0.998	0.000
C02.0 Dorsal surface of tongue	0.002	0.998	0.000
G24.3 Spasmodic torticollis	0.002	0.998	0.000
Q66.7 Pes cavus	0.000	0.998	0.002
G21 Secondary Parkinsonism	0.002	0.998	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.002	0.998	0.000
H90.3 Sensorineural hearing loss, bilateral	0.002	0.998	0.000
D70 Agranulocytosis	0.002	0.998	0.000
J81 Pulmonary oedema	0.002	0.998	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.998	0.002
C02.4 Lingual tonsil	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.000	0.998	0.002
S13.1 Dislocation of cervical vertebra	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.002	0.998	0.000
C02.1 Border of tongue	0.002	0.998	0.000
C49.9 Connective and soft tissue, unspecified	0.000	0.998	0.002
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.001	0.998	0.000
C68.1 Paraurethral glands	0.001	0.998	0.000
Q66.5 Congenital pes planus	0.000	0.998	0.002
Q66.4 Talipes calcaneovalgus	0.000	0.998	0.002
Q66.1 Talipes calcaneovarus	0.000	0.998	0.002
D33.3 Cranial nerves	0.000	0.998	0.002
Q66.6 Other congenital valgus deformities of feet	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.001	0.998	0.000
G23.3 Multiple system atrophy, cerebellar type	0.001	0.998	0.000
G23.2 Striatonigral degeneration	0.001	0.998	0.000
G23.0 Hallervorden-Spatz disease	0.001	0.998	0.000
Z36.9 Antenatal screening, unspecified	0.000	0.998	0.002
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.000	0.998	0.002
C68.9 Urinary organ, unspecified	0.001	0.998	0.000
H33.3 Retinal breaks without detachment	0.002	0.998	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.998	0.002
M66.3 Spontaneous rupture of flexor tendons	0.002	0.998	0.000
H50.0 Convergent concomitant strabismus	0.000	0.998	0.002
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.998	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.000	0.998	0.001
C68.0 Urethra	0.001	0.998	0.000
H92.0 Otalgia	0.001	0.998	0.000
Q61.8 Other cystic kidney diseases	0.000	0.998	0.001
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.001
D32.1 Spinal meninges	0.002	0.998	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.001	0.998	0.000
Q61.4 Renal dysplasia	0.000	0.998	0.001
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.001	0.998	0.000
G21.9 Secondary Parkinsonism, unspecified	0.001	0.998	0.000
G21.8 Other secondary Parkinsonism	0.001	0.998	0.000
G21.3 Postencephalitic Parkinsonism	0.001	0.998	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.001	0.998	0.000
G21.0 Malignant neuroleptic syndrome	0.001	0.998	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.001	0.998	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.002	0.998	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.001	0.998	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.001	0.998	0.000
G21.4 Vascular parkinsonism	0.001	0.998	0.000
Y91.9 Alcohol involvement, not otherwise specified	0.000	0.998	0.002
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.001	0.998	0.000
D75.0 Familial erythrocytosis	0.001	0.998	0.000
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
S13.5 Sprain and strain of thyroid region	0.001	0.998	0.000
S13.3 Multiple dislocations of neck	0.001	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.001	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.001	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.001
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.001	0.998	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.001	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.002	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.000	0.998	0.001
D72.9 Disorder of white blood cells, unspecified	0.001	0.998	0.000
D72.0 Genetic anomalies of leukocytes	0.001	0.998	0.000
D75.2 Essential thrombocytosis	0.001	0.998	0.000
H50.9 Strabismus, unspecified	0.000	0.998	0.001
M66.1 Rupture of synovium	0.001	0.998	0.000
N21.0 Calculus in bladder	0.002	0.998	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.001	0.999	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.001	0.999	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.001	0.999	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.001	0.999	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.001	0.999	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.001	0.999	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.001	0.999	0.000
G44.0 Cluster headache syndrome	0.001	0.999	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.001	0.999	0.000
G62.8 Other specified polyneuropathies	0.001	0.999	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.999	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.999	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.999	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.999	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.999	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.999	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.001	0.999	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.001	0.999	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.001	0.999	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.001	0.999	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.001	0.999	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.001	0.999	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.001	0.999	0.000
I51.9 Heart disease, unspecified	0.000	0.999	0.001
D32 Benign neoplasm of meninges	0.001	0.999	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.001	0.999	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.001	0.999	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.001	0.999	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.001	0.999	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.001	0.999	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.001	0.999	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.999	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.001	0.999	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.001	0.999	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.999	0.001
Q66.3 Other congenital varus deformities of feet	0.000	0.999	0.001
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.999	0.001
D72.1 Eosinophilia	0.001	0.999	0.000
F40.2 Specific (isolated) phobias	0.001	0.999	0.000
G62.0 Drug-induced polyneuropathy	0.001	0.999	0.000
D41.4 Bladder	0.001	0.999	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
C49.5 Connective and soft tissue of pelvis	0.000	0.999	0.001
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.001	0.999	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.000	0.999	0.001
H80 Otosclerosis	0.001	0.999	0.000
M66.19 Rupture of synovium (Site unspecified)	0.001	0.999	0.000
M66.18 Rupture of synovium (Other)	0.001	0.999	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.001	0.999	0.000
M66.16 Rupture of synovium (Lower leg)	0.001	0.999	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.001	0.999	0.000
M66.14 Rupture of synovium (Hand)	0.001	0.999	0.000
M66.13 Rupture of synovium (Forearm)	0.001	0.999	0.000
M66.12 Rupture of synovium (Upper arm)	0.001	0.999	0.000
M66.11 Rupture of synovium (Shoulder region)	0.001	0.999	0.000
M66.10 Rupture of synovium (Multiple sites)	0.001	0.999	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
B59 Pneumocystosis	0.001	0.999	0.000
K10.2 Inflammatory conditions of jaws	0.001	0.999	0.000
Y85.0 Sequelae of motor-vehicle accident	0.001	0.999	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.999	0.001
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.999	0.000
W18.3 Sports and athletics area	0.001	0.999	0.000
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999	0.000
R17 Unspecified jaundice	0.000	0.999	0.001
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
D01.2 Rectum	0.001	0.999	0.000
D56.1 Beta thalassaemia	0.001	0.999	0.000
S62.50 Fracture of thumb (closed)	0.000	0.999	0.001
H61.8 Other specified disorders of external ear	0.001	0.999	0.000
Q61.5 Medullary cystic kidney	0.000	0.999	0.001
T92 Sequelae of injuries of upper limb	0.000	0.999	0.001
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.001	0.999	0.000
C51.0 Labium majus	0.000	0.999	0.001
G62.1 Alcoholic polyneuropathy	0.001	0.999	0.000
H80.8 Other otosclerosis	0.001	0.999	0.000
H80.2 Cochlear otosclerosis	0.001	0.999	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.001	0.999	0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.001	0.999	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.001	0.999	0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
M41.56 Other secondary scoliosis (Lumbar region)	0.000	0.999	0.001
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.001	0.999	0.000
M70.22 Olecranon bursitis-Upper arm	0.001	0.999	0.000
S71.1 Open wound of thigh	0.000	0.999	0.001
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.000	0.999	0.001
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
K60.1 Chronic anal fissure	0.000	0.999	0.001
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.999	0.001
U80.0 Penicillin resistant agent	0.001	0.999	0.000
W10.8 Other specified place	0.001	0.999	0.000
G62 Other polyneuropathies	0.001	0.999	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.001	0.999	0.000
D32.0 Cerebral meninges	0.001	0.999	0.000
D56.9 Thalassaemia, unspecified	0.001	0.999	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.999	0.001
M41.5 Other secondary scoliosis	0.000	0.999	0.001
D56 Thalassaemia	0.001	0.999	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.999	0.001
Z42.0 Follow-up care involving plastic surgery of head and neck	0.001	0.999	0.000
Z99.3 Dependence on wheelchair	0.001	0.999	0.000
G35 Multiple sclerosis	0.001	0.999	0.000
M41 Scoliosis	0.000	0.999	0.001
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.001	0.999	0.000
D89.3 Immune reconstitution syndrome	0.001	0.999	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.999	0.000
H93.1 Tinnitus	0.001	0.999	0.000
K26.4 Chronic or unspecified with haemorrhage	0.000	0.999	0.001
R04.8 Haemorrhage from other sites in respiratory passages	0.001	0.999	0.000
W44.0 Home	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.999	0.001
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.999	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.001	0.999	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.001	0.999	0.000
H83 Other diseases of inner ear	0.001	0.999	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M41.59 Other secondary scoliosis (Site unspecified)	0.000	0.999	0.001
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M41.57 Other secondary scoliosis (Lumbosacral region)	0.000	0.999	0.001
M41.55 Other secondary scoliosis (Thoracolumbar region)	0.000	0.999	0.001
M41.53 Other secondary scoliosis (Cervicothoracic region)	0.000	0.999	0.001
M41.52 Other secondary scoliosis (Cervical region)	0.000	0.999	0.001
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)	0.000	0.999	0.001
M41.50 Other secondary scoliosis (Multiple sites in spine)	0.000	0.999	0.001
D56.8 Other thalassaemias	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations