TreeWAS – Variant ID: rs2392492

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
L57.0 Actinic keratosis	0.000	0.955	0.044
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.979	0.021
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.983	0.017
F41.2 Mixed anxiety and depressive disorder	0.000	0.984	0.016
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.984	0.015
L57.5 Actinic granuloma	0.000	0.984	0.015
L57.3 Poikiloderma of Civatte	0.000	0.984	0.015
L57.2 Cutis rhomboidalis nuchae	0.000	0.984	0.015
L57.1 Actinic reticuloid	0.000	0.984	0.015
I65.2 Occlusion and stenosis of carotid artery	0.014	0.986	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.986	0.014
L57.4 Cutis laxa senilis	0.000	0.987	0.013
I24.8 Other forms of acute ischaemic heart disease	0.000	0.989	0.011
H40 Glaucoma	0.010	0.990	0.000
H40.9 Glaucoma, unspecified	0.010	0.990	0.000
F41 Other anxiety disorders	0.000	0.990	0.010
H40.0 Glaucoma suspect	0.010	0.990	0.000
H40.2 Primary angle-closure glaucoma	0.009	0.991	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.991	0.009
H40.5 Glaucoma secondary to other eye disorders	0.008	0.992	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.992	0.008
H40.8 Other glaucoma	0.008	0.992	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.992	0.008
F41.1 Generalised anxiety disorder	0.000	0.992	0.008
H40.1 Primary open-angle glaucoma	0.008	0.992	0.000
H40.6 Glaucoma secondary to drugs	0.008	0.992	0.000
H40.4 Glaucoma secondary to eye inflammation	0.008	0.992	0.000
H40.3 Glaucoma secondary to eye trauma	0.008	0.992	0.000
F41.8 Other specified anxiety disorders	0.000	0.993	0.007
F41.3 Other mixed anxiety disorders	0.000	0.993	0.007
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.993	0.007
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.993	0.007
I24 Other acute ischaemic heart diseases	0.000	0.993	0.007
H40-H42 Glaucoma	0.007	0.993	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.994	0.006
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.994	0.006
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.994	0.006
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.994	0.006
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.006	0.994	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.006	0.994	0.000
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.000	0.995	0.005
L58 Radiodermatitis	0.000	0.995	0.005
L55 Sunburn	0.000	0.995	0.005
I24.1 Dressler's syndrome	0.000	0.995	0.005
H42 Glaucoma in diseases classified elsewhere	0.005	0.995	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.004	0.995	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.004	0.995	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.004	0.995	0.000
I65.1 Occlusion and stenosis of basilar artery	0.004	0.995	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.004	0.995	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.995	0.004
H21.8 Other specified disorders of iris and ciliary body	0.004	0.996	0.000
K61.0 Anal abscess	0.000	0.996	0.004
A09.9 Gastroenteritis and colitis of unspecified origin	0.000	0.996	0.004
H36.0 Diabetic retinopathy	0.004	0.996	0.000
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.996	0.004
H21 Other disorders of iris and ciliary body	0.004	0.996	0.000
L55.9 Sunburn, unspecified	0.000	0.996	0.004
L55.8 Other sunburn	0.000	0.996	0.004
L55.2 Sunburn of third degree	0.000	0.996	0.004
L55.1 Sunburn of second degree	0.000	0.996	0.004
L55.0 Sunburn of first degree	0.000	0.996	0.004
L58.9 Radiodermatitis, unspecified	0.000	0.996	0.004
L58.1 Chronic radiodermatitis	0.000	0.996	0.004
L58.0 Acute radiodermatitis	0.000	0.996	0.004
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.000	0.996	0.004
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.000	0.996	0.004
L59.0 Erythema ab igne [dermatitis ab igne]	0.000	0.996	0.004
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.001	0.996	0.003
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.004	0.996	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.004	0.996	0.000
Chapter VII Diseases of the eye and adnexa	0.004	0.996	0.000
I95.1 Orthostatic hypotension	0.004	0.996	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.004	0.996	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.004	0.996	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.996	0.003
C45.0 Mesothelioma of pleura	0.004	0.996	0.000
H20 Iridocyclitis	0.003	0.996	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.003	0.996	0.000
H47.2 Optic atrophy	0.003	0.997	0.000
D69.6 Thrombocytopenia, unspecified	0.003	0.997	0.000
H05.8 Other disorders of orbit	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.997	0.000
H10-H13 Disorders of conjunctiva	0.003	0.997	0.000
H05 Disorders of orbit	0.003	0.997	0.000
H11 Other disorders of conjunctiva	0.003	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
L56.4 Polymorphous light eruption	0.000	0.997	0.003
L56.3 Solar urticaria	0.000	0.997	0.003
L56.2 Photocontact dermatitis [berloque dermatitis]	0.000	0.997	0.003
L56.1 Drug photoallergic response	0.000	0.997	0.003
L56.0 Drug phototoxic response	0.000	0.997	0.003
J84.1 Other interstitial pulmonary diseases with fibrosis	0.003	0.997	0.000
H16 Keratitis	0.003	0.997	0.000
H36 Retinal disorders in diseases classified elsewhere	0.003	0.997	0.000
G40.9 Epilepsy, unspecified	0.000	0.997	0.003
H21.9 Disorder of iris and ciliary body, unspecified	0.003	0.997	0.000
H21.4 Pupillary membranes	0.003	0.997	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.003	0.997	0.000
H21.2 Degeneration of iris and ciliary body	0.003	0.997	0.000
H21.0 Hyphaema	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.003	0.997	0.000
H05.0 Acute inflammation of orbit	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
H15 Disorders of sclera	0.003	0.997	0.000
H11.9 Disorder of conjunctiva, unspecified	0.003	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
H17 Corneal scars and opacities	0.003	0.997	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.003	0.997	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.003	0.997	0.000
H11.2 Conjunctival scars	0.003	0.997	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.003	0.997	0.000
H46 Optic neuritis	0.003	0.997	0.000
H20.1 Chronic iridocyclitis	0.003	0.997	0.000
H04.1 Other disorders of lachrymal gland	0.003	0.997	0.000
H72.2 Other marginal perforations of tympanic membrane	0.003	0.997	0.000
C45 Mesothelioma	0.003	0.997	0.000
H50 Other strabismus	0.003	0.997	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.003	0.997	0.000
H47.6 Disorders of visual cortex	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.003	0.997	0.000
H47.4 Disorders of optic chiasm	0.003	0.997	0.000
H47.1 Papilloedema, unspecified	0.003	0.997	0.000
H50.0 Convergent concomitant strabismus	0.003	0.997	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.001	0.997	0.002
C45.9 Mesothelioma, unspecified	0.003	0.997	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.003	0.997	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.003	0.997	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.001	0.997	0.002
E05.9 Thyrotoxicosis, unspecified	0.003	0.997	0.000
H50.2 Vertical strabismus	0.003	0.997	0.000
H55-H59 Other disorders of eye and adnexa	0.003	0.997	0.000
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.003	0.997	0.000
H20.8 Other iridocyclitis	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
H50.5 Heterophoria	0.003	0.997	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.003	0.997	0.000
H47.3 Other disorders of optic disk	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
H05.2 Exophthalmic conditions	0.003	0.997	0.000
H11.3 Conjunctival haemorrhage	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
C45.7 Mesothelioma of other sites	0.003	0.997	0.000
H11.1 Conjunctival degenerations and deposits	0.003	0.997	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.003	0.997	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
H04 Disorders of lachrymal system	0.003	0.997	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.003	0.997	0.000
H05.9 Disorder of orbit, unspecified	0.003	0.997	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.003	0.997	0.000
H05.4 Enophthalmos	0.003	0.997	0.000
H05.3 Deformity of orbit	0.003	0.997	0.000
H05.1 Chronic inflammatory disorders of orbit	0.003	0.997	0.000
H16.0 Corneal ulcer	0.003	0.997	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.997	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.997	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.997	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.000	0.997	0.003
H36.8 Other retinal disorders in diseases classified elsewhere	0.002	0.997	0.000
G40 Epilepsy	0.000	0.997	0.003
H16.8 Other keratitis	0.002	0.997	0.000
H16.4 Corneal neovascularisation	0.002	0.997	0.000
H16.3 Interstitial and deep keratitis	0.002	0.997	0.000
H16.2 Keratoconjunctivitis	0.002	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.002	0.997	0.000
K61 Abscess of anal and rectal regions	0.000	0.997	0.003
H72.1 Attic perforation of tympanic membrane	0.002	0.997	0.000
K61.3 Ischiorectal abscess	0.000	0.997	0.003
A09 Diarrhoea and gastro-enteritis of presumed infectious origin	0.000	0.997	0.003
F03 Unspecified dementia	0.003	0.997	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
R79.8 Other specified abnormal findings of blood chemistry	0.003	0.997	0.000
H49 Paralytic strabismus	0.002	0.997	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.997	0.000
H15.8 Other disorders of sclera	0.002	0.997	0.000
H15.1 Episcleritis	0.002	0.997	0.000
H15.0 Scleritis	0.002	0.997	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.997	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.997	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
E86 Volume depletion	0.000	0.997	0.003
H30-H36 Disorders of choroid and retina	0.002	0.997	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.000	0.997	0.002
H04.8 Other disorders of lachrymal system	0.002	0.997	0.000
H17.8 Other corneal scars and opacities	0.002	0.997	0.000
H17.1 Other central corneal opacity	0.002	0.997	0.000
H17.0 Adherent leukoma	0.002	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.997	0.000
H11.8 Other specified disorders of conjunctiva	0.002	0.998	0.000
H04.4 Chronic inflammation of lachrymal passages	0.002	0.998	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.002	0.998	0.000
H51 Other disorders of binocular movement	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
H11.0 Pterygium	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
H53-H54 Visual disturbances and blindness	0.002	0.998	0.000
C45.2 Mesothelioma of pericardium	0.002	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.002	0.998	0.000
H50.8 Other specified strabismus	0.002	0.998	0.000
H50.6 Mechanical strabismus	0.002	0.998	0.000
H50.4 Other and unspecified heterotropia	0.002	0.998	0.000
H50.3 Intermittent heterotropia	0.002	0.998	0.000
H04.9 Disorder of lachrymal system, unspecified	0.002	0.998	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.002	0.998	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.002	0.998	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.002	0.998	0.000
G40.8 Other epilepsy	0.000	0.998	0.002
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.000	0.998	0.002
H10 Conjunctivitis	0.002	0.998	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
Z57.2 Occupational exposure to dust	0.002	0.998	0.000
H53.2 Diplopia	0.002	0.998	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
H31 Other disorders of choroid	0.002	0.998	0.000
H04.6 Other changes in lachrymal passages	0.002	0.998	0.000
H04.0 Dacryoadenitis	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.002	0.998	0.000
H13.3 Ocular pemphigoid	0.002	0.998	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
H13.0 Filarial infection of conjunctiva	0.002	0.998	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
H43-H45 Disorders of vitreous body and globe	0.002	0.998	0.000
M77.02 Medial epicondylitis (Upper arm)	0.002	0.998	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.000	0.998	0.002
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.000	0.998	0.002
N87.0 Mild cervical dysplasia	0.002	0.998	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.002	0.998	0.000
K61.4 Intrasphincteric abscess	0.000	0.998	0.002
K61.2 Anorectal abscess	0.000	0.998	0.002
K61.1 Rectal abscess	0.000	0.998	0.002
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
H65.3 Chronic mucoid otitis media	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.002	0.998	0.000
Q82.5 Congenital nonneoplastic naevus	0.002	0.998	0.000
R77.9 Abnormality of plasma protein, unspecified	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.002	0.998	0.000
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000
H49.3 Total (external) ophthalmoplegia	0.002	0.998	0.000
H49.1 Fourth [trochlear] nerve palsy	0.002	0.998	0.000
M95.0 Acquired deformity of nose	0.002	0.998	0.000
R77.8 Other specified abnormalities of plasma proteins	0.002	0.998	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.002	0.998	0.000
H30 Chorioretinal inflammation	0.002	0.998	0.000
H01 Other inflammation of eyelid	0.002	0.998	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.998	0.000
H51.9 Disorder of binocular movement, unspecified	0.002	0.998	0.000
H51.8 Other specified disorders of binocular movement	0.002	0.998	0.000
H51.2 Internuclear ophthalmoplegia	0.002	0.998	0.000
H51.1 Convergence insufficiency and excess	0.002	0.998	0.000
H51.0 Palsy of conjugate gaze	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.000	0.998	0.002
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.002	0.998	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.002	0.998	0.000
H31.0 Chorioretinal scars	0.002	0.998	0.000
K14.8 Other diseases of tongue	0.000	0.998	0.002
E04.1 Non-toxic single thyroid nodule	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
H49.2 Sixth [abducent] nerve palsy	0.002	0.998	0.000
R77 Other abnormalities of plasma proteins	0.002	0.998	0.000
G40.5 Special epileptic syndromes	0.000	0.998	0.002
H53 Visual disturbances	0.002	0.998	0.000
H10.8 Other conjunctivitis	0.002	0.998	0.000
H10.5 Blepharoconjunctivitis	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.002	0.998	0.000
H10.2 Other acute conjunctivitis	0.002	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.998	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.002	0.998	0.000
D69.9 Haemorrhagic condition, unspecified	0.002	0.998	0.000
D69.8 Other specified haemorrhagic conditions	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.998	0.000
D69.1 Qualitative platelet defects	0.002	0.998	0.000
D69.0 Allergic purpura	0.002	0.998	0.000
H50.9 Strabismus, unspecified	0.002	0.998	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
H06.3 Other disorders of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.001	0.998	0.000
C92.0 Acute myeloid leukaemia	0.002	0.998	0.000
H31.9 Disorder of choroid, unspecified	0.002	0.998	0.000
H31.8 Other specified disorders of choroid	0.002	0.998	0.000
H31.4 Choroidal detachment	0.002	0.998	0.000
H31.3 Choroidal haemorrhage and rupture	0.002	0.998	0.000
H31.2 Hereditary choroidal dystrophy	0.002	0.998	0.000
H31.1 Choroidal degeneration	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H18.3 Changes in corneal membranes	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.002	0.998	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
H53.4 Visual field defects	0.002	0.998	0.000
J84.8 Other specified interstitial pulmonary diseases	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.002	0.998	0.000
Z48.9 Surgical follow-up care, unspecified	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
H30.9 Chorioretinal inflammation, unspecified	0.002	0.998	0.000
H30.8 Other chorioretinal inflammations	0.002	0.998	0.000
H30.2 Posterior cyclitis	0.002	0.998	0.000
H30.1 Disseminated chorioretinal inflammation	0.002	0.998	0.000
H30.0 Focal chorioretinal inflammation	0.002	0.998	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.002	0.998	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
H01.9 Inflammation of eyelid, unspecified	0.002	0.998	0.000
H01.1 Non-infectious dermatoses of eyelid	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
S99 Other and unspecified injuries of ankle and foot	0.002	0.998	0.000
H50.1 Divergent concomitant strabismus	0.002	0.998	0.000
H65.2 Chronic serous otitis media	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
R77.2 Abnormality of alphafetoprotein	0.002	0.998	0.000
R77.1 Abnormality of globulin	0.002	0.998	0.000
R77.0 Abnormality of albumin	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.001	0.998	0.000
R79 Other abnormal findings of blood chemistry	0.002	0.998	0.000
H53.6 Night blindness	0.002	0.998	0.000
H53.5 Colour vision deficiencies	0.002	0.998	0.000
H53.3 Other disorders of binocular vision	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
H18.8 Other specified disorders of cornea	0.001	0.998	0.000
H57.1 Ocular pain	0.001	0.998	0.001
Z57.5 Occupational exposure to toxic agents in other industries	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.002	0.998	0.000
H53.8 Other visual disturbances	0.002	0.998	0.000
H44 Disorders of globe	0.002	0.998	0.000
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
F40-F48 Neurotic, stress-related and somatoform disorders	0.000	0.998	0.002
S90-S99 Injuries to the ankle and foot	0.002	0.998	0.000
H57.8 Other specified disorders of eye and adnexa	0.001	0.998	0.000
Q82.8 Other specified congenital malformations of skin	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.002	0.998	0.000
H01.0 Blepharitis	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.998	0.000
H68 Eustachian salpingitis and obstruction	0.001	0.998	0.000
H67 Otitis media in diseases classified elsewhere	0.001	0.998	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.002	0.998	0.000
H34.1 Central retinal artery occlusion	0.001	0.998	0.000
H34.0 Transient retinal artery occlusion	0.001	0.998	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.001	0.998	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.001	0.998	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.001	0.998	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.001	0.998	0.000
H73.1 Chronic myringitis	0.001	0.998	0.000
H73.0 Acute myringitis	0.001	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
E78.5 Hyperlipidaemia, unspecified	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.001	0.998	0.000
R74 Abnormal serum enzyme levels	0.002	0.998	0.000
H70 Mastoiditis and related conditions	0.001	0.998	0.000
H57.0 Anomalies of pupillary function	0.001	0.998	0.000
J92.0 Pleural plaque with presence of asbestos	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
K65.0 Acute peritonitis	0.002	0.998	0.000
S99.8 Other specified injuries of ankle and foot	0.001	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.001	0.998	0.000
H00 Hordeolum and chalazion	0.001	0.998	0.000
H01.8 Other specified inflammation of eyelid	0.001	0.998	0.000
K14.0 Glossitis	0.000	0.998	0.001
R45.8 Other symptoms and signs involving emotional state	0.001	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.001	0.998	0.000
Q82.9 Congenital malformation of skin, unspecified	0.001	0.998	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.001	0.998	0.000
Q82.3 Incontinentia pigmenti	0.001	0.998	0.000
Q82.2 Mastocytosis	0.001	0.998	0.000
Q82.1 Xeroderma pigmentosum	0.001	0.998	0.000
Q82.0 Hereditary lymphoedema	0.001	0.998	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.001	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.001	0.998	0.000
K14 Diseases of tongue	0.000	0.998	0.002
H04.2 Epiphora	0.001	0.998	0.000
H53.1 Subjective visual disturbances	0.001	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.001	0.998	0.000
F45 Somatoform disorders	0.000	0.998	0.001
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.001	0.998	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.002	0.998	0.000
H44.9 Disorder of globe, unspecified	0.001	0.999	0.000
H44.8 Other disorders of globe	0.001	0.999	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.001	0.999	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.001	0.999	0.000
H44.5 Degenerated conditions of globe	0.001	0.999	0.000
H44.4 Hypotony of eye	0.001	0.999	0.000
H44.3 Other degenerative disorders of globe	0.001	0.999	0.000
H44.1 Other endophthalmitis	0.001	0.999	0.000
H44.0 Purulent endophthalmitis	0.001	0.999	0.000
S92.1 Fracture of talus	0.001	0.999	0.000
G62.9 Polyneuropathy, unspecified	0.001	0.999	0.000
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.001	0.999	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.001	0.999	0.000
Q23.4 Hypoplastic left heart syndrome	0.001	0.999	0.000
Q23.3 Congenital mitral insufficiency	0.001	0.999	0.000
Q23.2 Congenital mitral stenosis	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.001	0.999	0.000
S92.4 Fracture of great toe	0.001	0.999	0.000
Z57.9 Occupational exposure to unspecified risk-factor	0.001	0.999	0.000
Z57.8 Occupational exposure to other risk-factors	0.001	0.999	0.000
Z57.7 Occupational exposure to vibration	0.001	0.999	0.000
Z57.6 Occupational exposure to extreme temperature	0.001	0.999	0.000
Z57.4 Occupational exposure to toxic agents in agriculture	0.001	0.999	0.000
Z57.1 Occupational exposure to radiation	0.001	0.999	0.000
Z57.0 Occupational exposure to noise	0.001	0.999	0.000
F48 Other neurotic disorders	0.000	0.999	0.001
S98 Traumatic amputation of ankle and foot	0.001	0.999	0.000
S97 Crushing injury of ankle and foot	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
S95 Injury of blood vessels at ankle and foot level	0.001	0.999	0.000
S94 Injury of nerves at ankle and foot level	0.001	0.999	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.001	0.999	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.001	0.999	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.001	0.999	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.001	0.999	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.001	0.999	0.000
H68.1 Obstruction of Eustachian tube	0.001	0.999	0.000
H68.0 Eustachian salpingitis	0.001	0.999	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.001	0.999	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
S22.3 Fracture of rib	0.000	0.999	0.001
M54.22 Cervicalgia (Cervical region)	0.001	0.999	0.000
H18.5 Hereditary corneal dystrophies	0.001	0.999	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
H69 Other disorders of Eustachian tube	0.001	0.999	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.001	0.999	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.001	0.999	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.001	0.999	0.000
S92.7 Multiple fractures of foot	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
S92.3 Fracture of metatarsal bone	0.001	0.999	0.000
S92.2 Fracture of other tarsal bone(s)	0.001	0.999	0.000
S92.0 Fracture of calcaneus	0.001	0.999	0.000
Y84.6 Urinary catheterisation	0.001	0.999	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.000	0.999	0.001
R78 Findings of drugs and other substances, not normally found in blood	0.001	0.999	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.001	0.999	0.000
S91 Open wound of ankle and foot	0.001	0.999	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.001	0.999	0.000
S92.10 Fracture of talus (closed)	0.001	0.999	0.000
H34.2 Other retinal artery occlusions	0.001	0.999	0.000
H70.8 Other mastoiditis and related conditions	0.001	0.999	0.000
H70.2 Petrositis	0.001	0.999	0.000
H70.1 Chronic mastoiditis	0.001	0.999	0.000
H70.0 Acute mastoiditis	0.001	0.999	0.000
F44 Dissociative [conversion] disorders	0.000	0.999	0.001
H52.7 Disorder of refraction, unspecified	0.001	0.999	0.000
H52.6 Other disorders of refraction	0.001	0.999	0.000
H52.5 Disorders of accommodation	0.001	0.999	0.000
H52.4 Presbyopia	0.001	0.999	0.000
M24.1 Other articular cartilage disorders	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations