TreeWAS – Variant ID: rs2399233

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T40.2 Other opioids	0.057	0.943	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.053	0.946	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.052	0.948	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.050	0.950	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.050	0.950	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.046	0.954	0.000
T39.1 4-Aminophenol derivatives	0.044	0.956	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.044	0.956	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.044	0.956	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.043	0.956	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.043	0.957	0.000
T43.2 Other and unspecified antidepressants	0.043	0.957	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.042	0.958	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.042	0.958	0.000
T46.1 Calcium-channel blockers	0.041	0.959	0.000
T40.1 Heroin	0.040	0.959	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.040	0.960	0.000
T40.6 Other and unspecified narcotics	0.040	0.960	0.000
T40.5 Cocaine	0.040	0.960	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.039	0.961	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.038	0.961	0.000
T40.8 Lysergide [LSD]	0.038	0.961	0.000
T40.7 Cannabis (derivatives)	0.038	0.961	0.000
T40.0 Opium	0.038	0.961	0.000
T40.3 Methadone	0.038	0.961	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.038	0.962	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.038	0.962	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.038	0.962	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.037	0.963	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.037	0.963	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.037	0.963	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.037	0.963	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.036	0.964	0.000
T36 Poisoning by systemic antibiotics	0.036	0.964	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.036	0.964	0.000
T46.7 Peripheral vasodilators	0.036	0.964	0.000
T43.6 Psychostimulants with abuse potential	0.036	0.964	0.000
T39.4 Antirheumatics, not elsewhere classified	0.036	0.964	0.000
T39.2 Pyrazolone derivatives	0.036	0.964	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.036	0.964	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.036	0.964	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.036	0.964	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.035	0.965	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.035	0.965	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.034	0.966	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.033	0.967	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.033	0.967	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.033	0.967	0.000
T38.1 Thyroid hormones and substitutes	0.032	0.968	0.000
T43.9 Psychotropic drug, unspecified	0.032	0.968	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.031	0.969	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.031	0.969	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.031	0.969	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.031	0.969	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.031	0.969	0.000
T44.0 Anticholinesterase agents	0.031	0.969	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.031	0.969	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.031	0.969	0.000
T47.2 Stimulant laxatives	0.030	0.969	0.000
T47.4 Other laxatives	0.030	0.969	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.030	0.969	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.030	0.970	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.030	0.970	0.000
T47.7 Emetics	0.030	0.970	0.000
T47.5 Digestants	0.030	0.970	0.000
T47.3 Saline and osmotic laxatives	0.030	0.970	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.030	0.970	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.029	0.970	0.000
T39.0 Salicylates	0.029	0.971	0.000
T38.9 Other and unspecified hormone antagonists	0.029	0.971	0.000
T38.7 Androgens and anabolic congeners	0.029	0.971	0.000
T38.4 Oral contraceptives	0.029	0.971	0.000
T38.2 Antithyroid drugs	0.029	0.971	0.000
T38.0 Glucocorticoids and synthetic analogues	0.029	0.971	0.000
T40.4 Other synthetic narcotics	0.028	0.971	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.028	0.971	0.000
T47.0 Histamine H(2)-receptor antagonists	0.028	0.972	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.028	0.972	0.000
T47.6 Antidiarrhoeal drugs	0.028	0.972	0.000
T38.5 Other oestrogens and progestogens	0.027	0.972	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.027	0.972	0.000
T48.4 Expectorants	0.027	0.972	0.000
T48.3 Antitussives	0.027	0.972	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.027	0.972	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.027	0.972	0.000
T48.0 Oxytocic drugs	0.027	0.972	0.000
H04.2 Epiphora	0.000	0.972	0.028
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.027	0.973	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.027	0.973	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.027	0.973	0.000
T37.5 Antiviral drugs	0.027	0.973	0.000
T37.4 Anthelminthics	0.027	0.973	0.000
T37.3 Other antiprotozoal drugs	0.027	0.973	0.000
T37.1 Antimycobacterial drugs	0.027	0.973	0.000
T37.0 Sulphonamides	0.027	0.973	0.000
T41.5 Therapeutic gases	0.026	0.974	0.000
T41.4 Anaesthetic, unspecified	0.026	0.974	0.000
T41.3 Local anaesthetics	0.026	0.974	0.000
T41.1 Intravenous anaesthetics	0.026	0.974	0.000
T41.0 Inhaled anaesthetics	0.026	0.974	0.000
T36.9 Systemic antibiotic, unspecified	0.026	0.974	0.000
T36.8 Other systemic antibiotics	0.026	0.974	0.000
T36.7 Antifungal antibiotics, systemically used	0.026	0.974	0.000
T36.6 Rifamycins	0.026	0.974	0.000
T36.5 Aminoglycosides	0.026	0.974	0.000
T36.2 Chloramphenicol group	0.026	0.974	0.000
T36.3 Macrolides	0.026	0.974	0.000
T48.5 Anti-common-cold drugs	0.025	0.974	0.000
T36.4 Tetracyclines	0.025	0.974	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.025	0.974	0.000
T36.0 Penicillins	0.025	0.975	0.000
T49.9 Topical agent, unspecified	0.025	0.975	0.000
T49.8 Other topical agents	0.025	0.975	0.000
T49.7 Dental drugs, topically applied	0.025	0.975	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.025	0.975	0.000
T49.5 Ophthalmological drugs and preparations	0.025	0.975	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.025	0.975	0.000
T49.3 Emollients, demulcents and protectants	0.025	0.975	0.000
T49.2 Local astringents and local detergents	0.025	0.975	0.000
T49.1 Antipruritics	0.025	0.975	0.000
T41.2 Other and unspecified general anaesthetics	0.025	0.975	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.025	0.975	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.024	0.976	0.000
T50.4 Drugs affecting uric acid metabolism	0.024	0.976	0.000
T50.7 Analeptics and opioid receptor antagonists	0.024	0.976	0.000
T50.5 Appetite depressants	0.024	0.976	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.024	0.976	0.000
T50.0 Mineralocorticoids and their antagonists	0.024	0.976	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.024	0.976	0.000
T42.0 Hydantoin derivatives	0.023	0.977	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.023	0.977	0.000
T50.8 Diagnostic agents	0.023	0.977	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.023	0.977	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.023	0.977	0.000
T50.1 Loop [high-ceiling] diuretics	0.023	0.977	0.000
T42.1 Iminostilbenes	0.023	0.977	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.022	0.977	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.022	0.978	0.000
T42.2 Succinimides and oxazolidinediones	0.022	0.978	0.000
Z36 Antenatal screening	0.022	0.978	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.022	0.978	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.022	0.978	0.000
T42.3 Barbiturates	0.022	0.978	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.021	0.979	0.000
H04 Disorders of lachrymal system	0.000	0.979	0.021
T43.0 Tricyclic and tetracyclic antidepressants	0.020	0.980	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.980	0.020
Z36.8 Other antenatal screening	0.020	0.980	0.000
Z36.9 Antenatal screening, unspecified	0.019	0.981	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.019	0.981	0.000
H04.8 Other disorders of lachrymal system	0.000	0.981	0.019
T45.9 Primarily systemic and haematological agent, unspecified	0.018	0.982	0.000
T45.8 Other primarily systemic and haematological agents	0.018	0.982	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.018	0.982	0.000
T45.6 Fibrinolysis-affecting drugs	0.018	0.982	0.000
T45.3 Enzymes, not elsewhere classified	0.018	0.982	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.018	0.982	0.000
T45.5 Anticoagulants	0.018	0.982	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.018	0.982	0.000
T45.2 Vitamins, not elsewhere classified	0.017	0.982	0.000
T45.4 Iron and its compounds	0.017	0.982	0.000
H04.6 Other changes in lachrymal passages	0.000	0.983	0.016
Z36.5 Antenatal screening for isoimmunisation	0.016	0.984	0.000
H04.0 Dacryoadenitis	0.000	0.984	0.016
T42.4 Benzodiazepines	0.015	0.985	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.015	0.985	0.000
H04.9 Disorder of lachrymal system, unspecified	0.000	0.985	0.015
T45.0 Antiallergic and antiemetic drugs	0.014	0.985	0.000
Z36.2 Other antenatal screening based on amniocentesis	0.015	0.985	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.986	0.014
H04.4 Chronic inflammation of lachrymal passages	0.000	0.986	0.013
K02.9 Dental caries, unspecified	0.013	0.987	0.000
G30.9 Alzheimer's disease, unspecified	0.000	0.987	0.013
G30 Alzheimer's disease	0.000	0.989	0.011
K92.1 Melaena	0.011	0.989	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.989	0.011
D68 Other coagulation defects	0.010	0.990	0.000
D69.6 Thrombocytopenia, unspecified	0.010	0.990	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.990	0.010
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.990	0.010
D68.9 Coagulation defect, unspecified	0.010	0.990	0.000
D69 Purpura and other haemorrhagic conditions	0.009	0.991	0.000
D68.5 Primary Thrombophilia	0.009	0.991	0.000
G30.8 Other Alzheimer's disease	0.000	0.991	0.009
G30.0 Alzheimer's disease with early onset	0.000	0.991	0.009
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.009	0.991	0.000
D68.8 Other specified coagulation defects	0.008	0.992	0.000
D68.0 Von Willebrand's disease	0.008	0.992	0.000
D68.2 Hereditary deficiency of other clotting factors	0.008	0.992	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.992	0.008
I77.1 Stricture of artery	0.000	0.992	0.008
D69.4 Other primary thrombocytopenia	0.008	0.992	0.000
D69.2 Other nonthrombocytopenic purpura	0.008	0.992	0.000
D68.4 Acquired coagulation factor deficiency	0.008	0.992	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.007	0.993	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.007	0.993	0.000
D69.8 Other specified haemorrhagic conditions	0.007	0.993	0.000
D66 Hereditary factor VIII deficiency	0.007	0.993	0.000
D68.6 Other Thrombophilia	0.007	0.993	0.000
D69.5 Secondary thrombocytopenia	0.007	0.993	0.000
D69.0 Allergic purpura	0.007	0.993	0.000
D69.9 Haemorrhagic condition, unspecified	0.007	0.993	0.000
I77 Other disorders of arteries and arterioles	0.000	0.993	0.007
D68.1 Hereditary factor XI deficiency	0.007	0.993	0.000
D67 Hereditary factor IX deficiency	0.007	0.993	0.000
I77.6 Arteritis, unspecified	0.000	0.993	0.007
G30-G32 Other degenerative diseases of the nervous system	0.000	0.994	0.006
D69.1 Qualitative platelet defects	0.006	0.994	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.006	0.994	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.006	0.994	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.994	0.006
I08.1 Disorders of both mitral and tricuspid valves	0.006	0.994	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.006	0.994	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.994	0.005
K02 Dental caries	0.005	0.994	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.995	0.005
Z35 Supervision of high-risk pregnancy	0.005	0.995	0.000
Z32 Pregnancy examination and test	0.005	0.995	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.995	0.005
I77.2 Rupture of artery	0.000	0.995	0.005
I77.5 Necrosis of artery	0.000	0.995	0.005
I77.4 Coeliac artery compression syndrome	0.000	0.995	0.005
I77.3 Arterial fibromuscular dysplasia	0.000	0.995	0.005
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.995	0.005
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.995	0.005
Z31 Procreative management	0.005	0.995	0.000
Z32.1 Pregnancy confirmed	0.005	0.995	0.000
Z35.5 Supervision of elderly primigravida	0.005	0.995	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.005	0.995	0.000
Z35.8 Supervision of other high-risk pregnancies	0.005	0.995	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.005	0.995	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.995	0.005
C82.3 Follicular lymphoma grade IIIa	0.000	0.995	0.004
Z38 Liveborn infants according to place of birth	0.004	0.995	0.000
Z33 Pregnant state, incidental	0.004	0.995	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.996	0.004
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.996	0.004
Z35.9 Supervision of high-risk pregnancy, unspecified	0.004	0.996	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.996	0.004
Z30 Contraceptive management	0.004	0.996	0.000
K02.8 Other dental caries	0.004	0.996	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.996	0.004
L29.0 Pruritus ani	0.004	0.996	0.000
Z32.0 Pregnancy, not (yet) confirmed	0.004	0.996	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.996	0.004
K02.5 Caries with pulp exposure	0.004	0.996	0.000
K02.4 Odontoclasia	0.004	0.996	0.000
K02.3 Arrested dental caries	0.004	0.996	0.000
K02.2 Caries of cementum	0.004	0.996	0.000
K02.0 Caries limited to enamel	0.004	0.996	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.996	0.004
Z35.7 Supervision of high-risk pregnancy due to social problems	0.004	0.996	0.000
Z35.6 Supervision of very young primigravida	0.004	0.996	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.004	0.996	0.000
D23.5 Skin of trunk	0.000	0.996	0.004
C82.0 Small cleaved cell, follicular	0.000	0.996	0.004
Z32.9 Pregnancy confirmed (erroneous code. See Z321)	0.004	0.996	0.000
Z37 Outcome of delivery	0.004	0.996	0.000
C82.6 Cutaneous follicle centre lymphoma	0.000	0.996	0.004
C82.5 Diffuse follicle centre lymphoma	0.000	0.996	0.004
I77.0 Arteriovenous fistula, acquired	0.000	0.996	0.004
I71 Aortic aneurysm and dissection	0.000	0.996	0.004
Z31.0 Tuboplasty or vasoplasty after previous sterilisation	0.004	0.996	0.000
I08 Multiple valve diseases	0.004	0.996	0.000
S02.4 Fracture of malar and maxillary bones	0.004	0.996	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.996	0.004
Z31.4 Procreative investigation and testing	0.004	0.996	0.000
C82.4 Follicular lymphoma grade IIIb	0.000	0.996	0.004
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.996	0.004
C83.3 Large cell (diffuse)	0.000	0.996	0.004
G31.0 Circumscribed brain atrophy	0.000	0.996	0.004
K02.1 Caries of dentin	0.004	0.996	0.000
Z31.9 Procreative management, unspecified	0.004	0.996	0.000
I71.0 Dissection of aorta [any part]	0.000	0.996	0.004
I78 Diseases of capillaries	0.000	0.996	0.004
I08.8 Other multiple valve diseases	0.004	0.996	0.000
Z31.2 In vitro fertilisation	0.004	0.996	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.996	0.004
I78.1 Naevus, nonneoplastic	0.000	0.996	0.004
Z30.0 General counselling and advice on contraception	0.004	0.996	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.996	0.004
Z31.5 Genetic counselling	0.004	0.996	0.000
Z31.1 Artifical insemination	0.004	0.996	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.004	0.996	0.000
I69 Sequelae of cerebrovascular disease	0.000	0.996	0.004
Z30.2 Sterilisation	0.004	0.996	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
Z39 Postpartum care and examination	0.004	0.996	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.996	0.004
C82.2 Large cell, follicular	0.000	0.996	0.003
C83.0 Small cell (diffuse)	0.000	0.996	0.004
Z31.6 General counselling and advice on procreation	0.003	0.996	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.996	0.004
Z30.3 Menstrual extraction	0.004	0.996	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.004	0.996	0.000
Z31.8 Other procreative management	0.003	0.996	0.000
Z37.1 Single stillbirth	0.004	0.996	0.000
Z30.8 Other contraceptive management	0.004	0.996	0.000
S02.20 Fracture of nasal bones (closed)	0.004	0.996	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.996	0.004
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.996	0.003
Z37.3 Twins, one liveborn and one stillborn	0.003	0.996	0.000
Z38.8 Other multiple, unspecified as to place of birth	0.003	0.996	0.000
Z38.7 Other multiple, born outside hospital	0.003	0.996	0.000
Z38.6 Other multiple, born in hospital	0.003	0.996	0.000
Z38.5 Twin, unspecified as to place of birth	0.003	0.996	0.000
Z38.4 Twin, born outside hospital	0.003	0.996	0.000
Z38.3 Twin, born in hospital	0.003	0.996	0.000
Z38.2 Singleton, unspecified as to place of birth	0.003	0.996	0.000
Z38.1 Singleton, born outside hospital	0.003	0.996	0.000
I74 Arterial embolism and thrombosis	0.000	0.996	0.003
G31.8 Other specified degenerative diseases of nervous system	0.000	0.997	0.003
Z31.3 Other assisted fertilisation methods	0.003	0.997	0.000
Z37.5 Other multiple births, all liveborn	0.003	0.997	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.997	0.003
Z30.9 Contraceptive management, unspecified	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.003
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.003
C83.2 Mixed small and large cell (diffuse)	0.000	0.997	0.003
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
Z30.4 Surveillance of contraceptive drugs	0.003	0.997	0.000
Z37.9 Outcome of delivery unspecified	0.003	0.997	0.000
Z37.7 Other multiple births, all stillborn	0.003	0.997	0.000
Z37.6 Other multiple births, some liveborn	0.003	0.997	0.000
Z37.4 Twins, both stillborn	0.003	0.997	0.000
O46.9 Antepartum haemorrhage, unspecified	0.003	0.997	0.000
Z38.0 Singleton, born in hospital	0.003	0.997	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.997	0.003
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.997	0.003
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.997	0.003
C83.7 Burkitt's tumour	0.000	0.997	0.003
C85.0 Lymphosarcoma	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.003	0.997	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
I70 Atherosclerosis	0.000	0.997	0.003
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.997	0.003
I74.5 Embolism and thrombosis of iliac artery	0.000	0.997	0.003
S02.41 Fracture of malar and maxillary bones (open)	0.003	0.997	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.997	0.003
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.997	0.003
I78.9 Disease of capillaries, unspecified	0.000	0.997	0.003
I79.1 Aortitis in diseases classified elsewhere	0.000	0.997	0.003
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.997	0.003
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.997	0.003
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.003	0.997	0.000
I08.9 Multiple valve disease, unspecified	0.003	0.997	0.000
Z39.2 Routine postpartum follow-up	0.003	0.997	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.997	0.003
D52.9 Folate deficiency anaemia, unspecified	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.000	0.997	0.003
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.997	0.003
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.997	0.003
H53.8 Other visual disturbances	0.003	0.997	0.000
I78.8 Other diseases of capillaries	0.000	0.997	0.003
O46 Antepartum haemorrhage, not elsewhere classified	0.003	0.997	0.000
Z39.1 Care and examination of lactating mother	0.003	0.997	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
H71 Cholesteatoma of middle ear	0.003	0.997	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.003	0.997	0.000
I73 Other peripheral vascular diseases	0.000	0.997	0.003
O35 Maternal care for known or suspected foetal abnormality and damage	0.003	0.997	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.997	0.002
Z34 Supervision of normal pregnancy	0.003	0.997	0.000
L29 Pruritus	0.003	0.997	0.000
H73.8 Other specified disorders of tympanic membrane	0.003	0.997	0.000
O48 Prolonged pregnancy	0.003	0.997	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.997	0.002
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.997	0.002
K86.1 Other chronic pancreatitis	0.003	0.997	0.000
I70.1 Atherosclerosis of renal artery	0.000	0.997	0.002
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.997	0.002
I74.8 Embolism and thrombosis of other arteries	0.000	0.997	0.002
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.997	0.002
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.997	0.002
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.002
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.997	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.003	0.997	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.997	0.002
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.997	0.002
S02.21 Fracture of nasal bones (open)	0.002	0.997	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.997	0.002
E11.4 With neurological complications	0.000	0.997	0.002
G62.9 Polyneuropathy, unspecified	0.000	0.997	0.002
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.002
H66 Suppurative and unspecified otitis media	0.002	0.998	0.000
I70.9 Generalised and unspecified atherosclerosis	0.000	0.998	0.002
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.998	0.002
I70.8 Atherosclerosis of other arteries	0.000	0.998	0.002
C94 Other leukaemias of specified cell type	0.000	0.998	0.002
C86 Other specified types of T/NK-cell lymphoma	0.000	0.998	0.002
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
O36 Maternal care for other known or suspected foetal problems	0.002	0.998	0.000
C93 Monocytic leukaemia	0.000	0.998	0.002
G62 Other polyneuropathies	0.000	0.998	0.002
C95 Leukaemia of unspecified cell type	0.000	0.998	0.002
O47 False labour	0.002	0.998	0.000
L29.2 Pruritus vulvae	0.002	0.998	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.998	0.002
O41.0 Oligohydramnios	0.002	0.998	0.000
Z37.2 Twins, both liveborn	0.002	0.998	0.000
H65-H75 Diseases of middle ear and mastoid	0.002	0.998	0.000
N97.9 Female infertility, unspecified	0.002	0.998	0.000
O46.8 Other antepartum haemorrhage	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.998	0.002
K92 Other diseases of digestive system	0.002	0.998	0.000
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.002	0.998	0.000
J36 Peritonsillar abscess	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.000	0.998	0.002
O47.0 False labour before 37 completed weeks of gestation	0.002	0.998	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.002	0.998	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.002	0.998	0.000
S02.6 Fracture of mandible	0.002	0.998	0.000
L29.8 Other pruritus	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
S02.0 Fracture of vault of skull	0.002	0.998	0.000
H52.2 Astigmatism	0.002	0.998	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.002	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.002	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.002	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.002	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.002	0.998	0.000
C88 Malignant immunoproliferative diseases	0.000	0.998	0.002
C92 Myeloid leukaemia	0.000	0.998	0.002
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
L29.1 Pruritus scroti	0.002	0.998	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.998	0.002
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
H66.9 Otitis media, unspecified	0.002	0.998	0.000
L29.3 Anogenital pruritus, unspecified	0.002	0.998	0.000
Z37.0 Single live birth	0.002	0.998	0.000
O36.4 Maternal care for intra-uterine death	0.002	0.998	0.000
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.998	0.002
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.998	0.002
H53.0 Amblyopia ex anopsia	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
S02.5 Fracture of tooth	0.002	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.998	0.002
K92.8 Other specified diseases of digestive system	0.002	0.998	0.000
L29.9 Pruritus, unspecified	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
O31 Complications specific to multiple gestation	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
O42 Premature rupture of membranes	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.998	0.002
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.002
C96.8 Histiocytic sarcoma	0.000	0.998	0.002
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.998	0.002
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.998	0.002
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.998	0.002
C96.3 True histiocytic lymphoma	0.000	0.998	0.002
C96.2 Malignant mast cell tumour	0.000	0.998	0.002
C96.1 Malignant histiocytosis	0.000	0.998	0.002
C96.0 Letterer-Siwe disease	0.000	0.998	0.002
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
H73.0 Acute myringitis	0.002	0.998	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.998	0.000
O36.6 Maternal care for excessive foetal growth	0.002	0.998	0.000
G62.1 Alcoholic polyneuropathy	0.000	0.998	0.002
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.002
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.002
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.002
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.002
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.002
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.002
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
O36.5 Maternal care for poor foetal growth	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.000	0.998	0.002
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.998	0.002
G62.0 Drug-induced polyneuropathy	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations