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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2405522
log Bayes Factor = 0.0449168
Chromosome 5   position 131,741,696  (GRCh37) Explore rs2405522 on Ensembl!
Variant rs2405522 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C83.3 Large cell (diffuse)
0.000 0.856 0.144
C83 Diffuse non-Hodgkin's lymphoma
0.000 0.856 0.144
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.000 0.859 0.141
C92 Myeloid leukaemia
0.000 0.860 0.140
C92.0 Acute myeloid leukaemia
0.000 0.862 0.138
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.000 0.870 0.130
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.000 0.871 0.129
C91 Lymphoid leukaemia
0.000 0.877 0.123
C85.1 B-cell lymphoma, unspecified
0.000 0.877 0.123
C83.7 Burkitt's tumour
0.000 0.882 0.118
C88 Malignant immunoproliferative diseases
0.000 0.882 0.118
C92.9 Myeloid leukaemia, unspecified
0.000 0.885 0.115
C91.1 Chronic lymphocytic leukaemia
0.000 0.887 0.113
C92.7 Other myeloid leukaemia
0.000 0.891 0.108
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.000 0.892 0.108
C94 Other leukaemias of specified cell type
0.000 0.894 0.106
C91.5 Adult T-cell leukaemia
0.000 0.896 0.103
C83.6 Undifferentiated (diffuse)
0.000 0.897 0.103
C83.4 Immunoblastic (diffuse)
0.000 0.897 0.103
C92.5 Acute myelomonocytic leukaemia
0.000 0.897 0.103
C83.2 Mixed small and large cell (diffuse)
0.000 0.897 0.102
C84 Peripheral and cutaneous T-cell lymphomas
0.000 0.898 0.102
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.899 0.101
C83.1 Small cleaved cell (diffuse)
0.000 0.899 0.101
C83.5 Lymphoblastic (diffuse)
0.000 0.899 0.101
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.000 0.899 0.101
C92.8 Acute myeloid leukaemia with multilineage dysplasia
0.000 0.900 0.100
C92.6 Acute myeloid leukaemia with 11q23-abnormality
0.000 0.900 0.100
C92.3 Myeloid sarcoma
0.000 0.900 0.100
C92.2 Subacute myeloid leukaemia
0.000 0.900 0.100
C91.9 Lymphoid leukaemia, unspecified
0.000 0.900 0.100
C93 Monocytic leukaemia
0.000 0.900 0.100
C81 Hodgkin's disease
0.000 0.900 0.099
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.000 0.905 0.095
C86 Other specified types of T/NK-cell lymphoma
0.000 0.906 0.094
C88.0 Waldenstrom's macroglobulinaemia
0.000 0.907 0.093
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.000 0.907 0.093
C85.0 Lymphosarcoma
0.000 0.907 0.093
C95 Leukaemia of unspecified cell type
0.000 0.908 0.092
C92.1 Chronic myeloid leukaemia
0.000 0.908 0.091
C92.4 Acute promyelocytic leukaemia
0.000 0.908 0.091
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.911 0.088
C91.7 Other lymphoid leukaemia
0.000 0.911 0.088
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.911 0.088
C91.3 Prolymphocytic leukaemia
0.000 0.911 0.088
C91.2 Subacute lymphocytic leukaemia
0.000 0.911 0.088
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.000 0.915 0.085
C88.9 Malignant immunoproliferative disease, unspecified
0.000 0.915 0.084
C88.7 Other malignant immunoproliferative diseases
0.000 0.915 0.084
C88.3 Immunoproliferative small intestinal disease
0.000 0.915 0.084
C88.2 Gamma heavy chain disease
0.000 0.915 0.084
C88.1 Alpha heavy chain disease
0.000 0.915 0.084
C81.1 Nodular sclerosis
0.000 0.919 0.081
C84.8 Cutaneous T-cell lymphoma, unspecified
0.000 0.919 0.081
C85.7 Other specified types of non-Hodgkin's lymphoma
0.000 0.919 0.081
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified
0.000 0.921 0.079
C94.4 Acute panmyelosis
0.000 0.923 0.077
C94.7 Other specified leukaemias
0.000 0.924 0.076
C94.5 Acute myelofibrosis
0.000 0.924 0.076
C94.3 Mast cell leukaemia
0.000 0.924 0.076
C94.2 Acute megakaryoblastic leukaemia
0.000 0.924 0.076
C94.1 Chronic erythraemia
0.000 0.924 0.076
C94.0 Acute erythraemia and erythroleukaemia
0.000 0.924 0.076
C82.2 Large cell, follicular
0.000 0.926 0.074
C81.2 Mixed cellularity
0.000 0.926 0.074
C84.9 Mature T/NK-cell lymphoma, unspecified
0.000 0.927 0.073
C84.7 Anaplastic large cell lymphoma, ALK-negative
0.000 0.927 0.073
C84.6 Anaplastic large cell lymphoma, ALK-positive
0.000 0.927 0.073
C84.3 Lymphoepithelioid lymphoma
0.000 0.927 0.073
C84.2 T-zone lymphoma
0.000 0.927 0.073
C84.1 Sezary's diease
0.000 0.927 0.073
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.927 0.073
C96.8 Histiocytic sarcoma
0.000 0.927 0.073
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.000 0.927 0.073
C96.6 Unifocal Langerhans-cell histiocytosis
0.000 0.927 0.073
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis
0.000 0.927 0.073
C96.4 Sarcoma of dendritic cells (accessory cells)
0.000 0.927 0.073
C96.3 True histiocytic lymphoma
0.000 0.927 0.073
C96.2 Malignant mast cell tumour
0.000 0.927 0.073
C96.1 Malignant histiocytosis
0.000 0.927 0.073
C96.0 Letterer-Siwe disease
0.000 0.927 0.073
C93.9 Monocytic leukaemia, unspecified
0.000 0.928 0.072
C93.7 Other monocytic leukaemia
0.000 0.928 0.072
C93.3 Juvenile myelomonocytic leukaemia
0.000 0.928 0.072
C93.2 Subacute monocytic leukaemia
0.000 0.928 0.072
C93.0 Acute monocytic leukaemia
0.000 0.928 0.072
C84.0 Mycosis fungoides
0.000 0.928 0.072
C81.4 Lymphocyte-rich classical Hodgkin lymphoma
0.000 0.928 0.071
C81.3 Lymphocytic depletion
0.000 0.928 0.071
C84.5 Other and unspecified T-cell lymphomas
0.000 0.929 0.071
C93.1 Chronic monocytic leukaemia
0.000 0.929 0.070
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.000 0.930 0.070
C81.0 Lymphocytic predominance
0.000 0.930 0.069
C95.0 Acute leukaemia of unspecified cell type
0.000 0.932 0.068
C82.3 Follicular lymphoma grade IIIa
0.000 0.932 0.068
C86.6 Primary cutaneous CD30-positive T-cell proliferations
0.000 0.932 0.068
C86.4 Blastic NK-cell lymphoma
0.000 0.932 0.068
C86.3 Subcutaneous panniculitis-like T-cell lymphoma
0.000 0.932 0.068
C86.2 Enteropathy-type (intestinal) T-cell lymphoma
0.000 0.932 0.068
C86.1 Hepatosplenic T-cell lymphoma
0.000 0.932 0.068
C86.0 Extranodal NK/T-cell lymphoma, nasal type
0.000 0.932 0.068
C81.7 Other Hodgkin's disease
0.000 0.933 0.067
C82.6 Cutaneous follicle centre lymphoma
0.000 0.933 0.067
C82.5 Diffuse follicle centre lymphoma
0.000 0.933 0.067
C84.4 Peripheral T-cell lymphoma
0.000 0.933 0.067
C91.4 Hairy-cell leukaemia
0.000 0.933 0.067
C90 Multiple myeloma and malignant plasma cell neoplasms
0.000 0.933 0.067
C82.0 Small cleaved cell, follicular
0.000 0.933 0.067
C95.7 Other leukaemia of unspecified cell type
0.000 0.933 0.066
C95.2 Subacute leukaemia of unspecified cell type
0.000 0.933 0.066
C82.4 Follicular lymphoma grade IIIb
0.000 0.935 0.065
C95.1 Chronic leukaemia of unspecified cell type
0.000 0.936 0.064
C82.1 Mixed small cleaved and large cell, follicular
0.000 0.937 0.063
C86.5 Angioimmunoblastic T-cell lymphoma
0.000 0.939 0.061
C83.0 Small cell (diffuse)
0.000 0.940 0.060
C81.9 Hodgkin's disease, unspecified
0.000 0.940 0.059
C95.9 Leukaemia, unspecified
0.000 0.941 0.058
C91.0 Acute lymphoblastic leukaemia
0.000 0.943 0.056
C90.1 Plasma cell leukaemia
0.000 0.950 0.050
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.000 0.951 0.049
C90.2 Plasmacytoma, extramedullary
0.000 0.955 0.045
C90.3 Solitary plasmacytoma
0.000 0.957 0.043
R79.8 Other specified abnormal findings of blood chemistry
0.000 0.962 0.038
K50.1 Crohn's disease of large intestine
0.033 0.967 0.000
K50 Crohn's disease [regional enteritis]
0.032 0.968 0.000
K50.9 Crohn's disease, unspecified
0.031 0.969 0.000
K50.0 Crohn's disease of small intestine
0.030 0.970 0.000
C90.0 Multiple myeloma
0.000 0.974 0.026
K50.8 Other Crohn's disease
0.023 0.977 0.000
Y40.8 Other systemic antibiotics
0.000 0.984 0.016
D12.3 Transverse colon
0.000 0.987 0.013
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters
0.012 0.988 0.000
K50-K52 Noninfective enteritis and colitis
0.011 0.989 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.990 0.010
K51 Ulcerative colitis
0.010 0.990 0.000
R79 Other abnormal findings of blood chemistry
0.000 0.991 0.009
M18.1 Other primary arthrosis of first carpometacarpal joint
0.000 0.991 0.009
K51.9 Ulcerative colitis, unspecified
0.009 0.991 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.000 0.991 0.009
K51.3 Ulcerative (chronic) rectosigmoiditis
0.008 0.992 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.008 0.992 0.000
K51.5 Mucosal proctocolitis
0.007 0.993 0.000
Z51.0 Radiotherapy session
0.007 0.993 0.000
K51.8 Other ulcerative colitis
0.007 0.993 0.000
M18 Arthrosis of first carpometacarpal joint
0.000 0.993 0.007
K51.0 Ulcerative (chronic) enterocolitis
0.007 0.993 0.000
K51.2 Ulcerative (chronic) proctitis
0.006 0.994 0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified
0.000 0.994 0.006
D59.1 Other autoimmune haemolytic anaemias
0.000 0.994 0.006
K51.4 Pseudopolyposis of colon
0.006 0.994 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.000 0.994 0.006
R79.0 Abnormal level of blood mineral
0.000 0.995 0.005
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.005 0.995 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.000 0.995 0.005
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.995 0.005
I24.8 Other forms of acute ischaemic heart disease
0.005 0.995 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.000 0.995 0.005
D23.2 Skin of ear and external auricular canal
0.000 0.995 0.005
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.000 0.995 0.005
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.000 0.995 0.005
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.000 0.995 0.005
R47.0 Dysphasia and aphasia
0.005 0.995 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.000 0.995 0.005
Z53.9 Procedure not carried out, unspecified reason
0.000 0.995 0.005
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.000 0.995 0.005
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.000 0.995 0.005
C18.9 Colon, unspecified
0.000 0.995 0.005
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.000 0.995 0.005
M54.29 Cervicalgia-Site unspe
0.000 0.995 0.005
C18.1 Appendix
0.000 0.995 0.005
F23.9 Acute and transient psychotic disorder, unspecified
0.005 0.995 0.000
T91.3 Sequelae of injury of spinal cord
0.000 0.996 0.004
R79.9 Abnormal finding of blood chemistry, unspecified
0.000 0.996 0.004
D59 Acquired haemolytic anaemia
0.000 0.996 0.004
Z01.8 Other specified special examinations
0.004 0.996 0.000
T39.0 Salicylates
0.000 0.996 0.004
C18 Malignant neoplasm of colon
0.000 0.996 0.004
F23 Acute and transient psychotic disorders
0.004 0.996 0.000
G31.8 Other specified degenerative diseases of nervous system
0.000 0.996 0.004
Y40 Systemic antibiotics
0.000 0.996 0.004
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters
0.004 0.996 0.000
E61.1 Iron deficiency
0.004 0.996 0.000
C24.1 Ampulla of Vater
0.000 0.996 0.004
T85.4 Mechanical complication of breast prosthesis and implant
0.000 0.996 0.004
T85.2 Mechanical complication of intraocular lens
0.000 0.996 0.004
Z75.1 Person awaiting admission to adequate facility elsewhere
0.000 0.996 0.004
K52 Other non-infective gastro-enteritis and colitis
0.004 0.996 0.000
Y40.6 Rifamycins
0.000 0.996 0.004
C18.3 Hepatic flexure
0.000 0.996 0.004
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.000 0.996 0.004
D59.4 Other nonautoimmune haemolytic anaemias
0.000 0.996 0.004
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.004 0.996 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.996 0.004
F25 Schizoaffective disorders
0.004 0.996 0.000
D59.9 Acquired haemolytic anaemia, unspecified
0.000 0.996 0.003
C18.8 Overlapping lesion of colon
0.000 0.996 0.003
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.003 0.997 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.003 0.997 0.000
C18.5 Splenic flexure
0.000 0.997 0.003
F23.3 Other acute predominantly delusional psychotic disorders
0.003 0.997 0.000
D59.8 Other acquired haemolytic anaemias
0.000 0.997 0.003
D59.6 Haemoglobinuria due to haemolysis from other external causes
0.000 0.997 0.003
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]
0.000 0.997 0.003
D59.3 Haemolytic-uraemic syndrome
0.000 0.997 0.003
D59.2 Drug-induced nonautoimmune haemolytic anaemia
0.000 0.997 0.003
Y40.4 Tetracyclines
0.000 0.997 0.003
T91.8 Sequelae of other specified injuries of neck and trunk
0.000 0.997 0.003
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.997 0.003
Y40.7 Antifungal antibiotics, systemically used
0.000 0.997 0.003
C24.9 Biliary tract, unspecified
0.000 0.997 0.003
F23.2 Acute schizophrenia-like psychotic disorder
0.003 0.997 0.000
F25.1 Schizoaffective disorder, depressive type
0.003 0.997 0.000
D59.0 Drug-induced autoimmune haemolytic anaemia
0.000 0.997 0.003
F23.8 Other acute and transient psychotic disorders
0.003 0.997 0.000
Y40.2 Chloramphenicol group
0.000 0.997 0.003
C18.0 Caecum
0.000 0.997 0.003
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.003 0.997 0.000
Y40.3 Macrolides
0.000 0.997 0.003
C15-C26 Malignant neoplasms of digestive organs
0.000 0.997 0.003
K52.3 Indeterminate colitis
0.003 0.997 0.000
T91 Sequelae of injuries of neck and trunk
0.000 0.997 0.003
F29 Unspecified nonorganic psychosis
0.003 0.997 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.997 0.003
F25.9 Schizoaffective disorder, unspecified
0.003 0.997 0.000
F25.0 Schizoaffective disorder, manic type
0.003 0.997 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.997 0.003
Y40.5 Aminoglycosides
0.000 0.997 0.003
C17.9 Small intestine, unspecified
0.000 0.997 0.003
D47.1 Chronic myeloproliferative disease
0.000 0.997 0.003
F25.2 Schizoaffective disorder, mixed type
0.003 0.997 0.000
G71.0 Muscular dystrophy
0.000 0.997 0.003
C17 Malignant neoplasm of small intestine
0.000 0.997 0.003
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.997 0.003
C18.6 Descending colon
0.000 0.997 0.003
F20.0 Paranoid schizophrenia
0.003 0.997 0.000
G31.0 Circumscribed brain atrophy
0.000 0.997 0.003
Y40.1 Cefalosporins and other -lactam antibiotics
0.000 0.997 0.003
C24.8 Overlapping lesion of biliary tract
0.000 0.997 0.003
T78.3 Angioneurotic oedema
0.000 0.997 0.003
F25.8 Other schizoaffective disorders
0.003 0.997 0.000
I82.8 Embolism and thrombosis of other specified veins
0.003 0.997 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.003 0.997 0.000
F21 Schizotypal disorder
0.003 0.997 0.000
F20 Schizophrenia
0.003 0.997 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.000 0.997 0.003
C23 Malignant neoplasm of gallbladder
0.000 0.997 0.003
F28 Other nonorganic psychotic disorders
0.003 0.997 0.000
F24 Induced delusional disorder
0.003 0.997 0.000
D47.2 Monoclonal gammopathy
0.000 0.997 0.003
T91.1 Sequelae of fracture of spine
0.000 0.997 0.003
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.000 0.997 0.003
C24.0 Extrahepatic bile duct
0.000 0.997 0.003
R20.2 Paraesthesia of skin
0.000 0.997 0.003
C18.7 Sigmoid colon
0.000 0.997 0.003
E05.5 Thyroid crisis or storm
0.000 0.997 0.003
E05.4 Thyrotoxicosis factitia
0.000 0.997 0.003
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.997 0.003
F22 Persistent delusional disorders
0.003 0.997 0.000
E05.8 Other thyrotoxicosis
0.000 0.997 0.002
C44.2 Skin of ear and external auricular canal
0.000 0.997 0.003
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.997 0.002
Q62.5 Duplication of ureter
0.000 0.997 0.003
Z51.3 Blood transfusion without reported diagnosis
0.000 0.997 0.003
T91.5 Sequelae of injury of intra-abdominal and pelvic organs
0.000 0.997 0.002
T91.4 Sequelae of injury of intrathoracic organs
0.000 0.997 0.002
T91.0 Sequelae of superficial injury and open wound of neck and trunk
0.000 0.997 0.002
E61 Deficiency of other nutrient elements
0.003 0.997 0.000
C17.1 Jejunum
0.000 0.997 0.002
A41.8 Other specified septicaemia
0.000 0.998 0.002
K52.8 Other specified non-infective gastro-enteritis and colitis
0.002 0.998 0.000
C17.8 Overlapping lesion of small intestine
0.000 0.998 0.002
C17.3 Meckel's diverticulum
0.000 0.998 0.002
T91.2 Sequelae of other fracture of thorax and pelvis
0.000 0.998 0.002
G31.2 Degeneration of nervous system due to alcohol
0.000 0.998 0.002
F20.8 Other schizophrenia
0.002 0.998 0.000
C18.4 Transverse colon
0.000 0.998 0.002
F20.2 Catatonic schizophrenia
0.002 0.998 0.000
D55-D59 Haemolytic anaemias
0.000 0.998 0.002
R47 Speech disturbances, not elsewhere classified
0.002 0.998 0.000
C17.2 Ileum
0.000 0.998 0.002
F20.6 Simple schizophrenia
0.002 0.998 0.000
F20.4 Postschizophrenic depression
0.002 0.998 0.000
F20.3 Undifferentiated schizophrenia
0.002 0.998 0.000
F20.1 Hebephrenic schizophrenia
0.002 0.998 0.000
T91.9 Sequelae of unspecified injury of neck and trunk
0.000 0.998 0.002
F22.9 Persistent delusional disorder, unspecified
0.002 0.998 0.000
E61.2 Magnesium deficiency
0.002 0.998 0.000
R40.2 Coma, unspecified
0.000 0.998 0.002
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.000 0.998 0.002
G31.1 Senile degeneration of brain, not elsewhere classified
0.000 0.998 0.002
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.000 0.998 0.002
C18.2 Ascending colon
0.000 0.998 0.002
Q61.5 Medullary cystic kidney
0.000 0.998 0.002
F22.8 Other persistent delusional disorders
0.002 0.998 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.998 0.002
C17.0 Duodenum
0.000 0.998 0.002
Y40.0 Penicillins
0.000 0.998 0.002
F20.5 Residual schizophrenia
0.002 0.998 0.000
D56 Thalassaemia
0.000 0.998 0.002
C15 Malignant neoplasm of oesophagus
0.000 0.998 0.002
E21.3 Hyperparathyroidism, unspecified
0.000 0.998 0.002
E61.9 Deficiency of nutrient element, unspecified
0.002 0.998 0.000
E61.8 Deficiency of other specified nutrient elements
0.002 0.998 0.000
E61.7 Deficiency of multiple nutrient elements
0.002 0.998 0.000
E61.6 Vanadium deficiency
0.002 0.998 0.000
E61.5 Molybdenum deficiency
0.002 0.998 0.000
E61.4 Chromium deficiency
0.002 0.998 0.000
E61.3 Manganese deficiency
0.002 0.998 0.000
E61.0 Copper deficiency
0.002 0.998 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.998 0.002
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.000 0.998 0.002
L89.1 Stage II decubitus ulcer
0.002 0.998 0.000
Y40.9 Systemic antibiotic, unspecified
0.000 0.998 0.002
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.000 0.998 0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.000 0.998 0.002
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.998 0.002
Q61.3 Polycystic kidney, unspecified
0.000 0.998 0.002
Q61 Cystic kidney disease
0.000 0.998 0.002
D37.5 Rectum
0.000 0.998 0.002
D57 Sickle-cell disorders
0.000 0.998 0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.998 0.002
D55 Anaemia due to enzyme disorders
0.000 0.998 0.002
D58 Other hereditary haemolytic anaemias
0.000 0.998 0.002
C15.3 Upper third of oesophagus
0.000 0.998 0.002
D56.3 Thalassaemia trait
0.000 0.998 0.002
F22.0 Delusional disorder
0.002 0.998 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.002 0.998 0.000
Z33 Pregnant state, incidental
0.002 0.998 0.000
L20.9 Atopic dermatitis, unspecified
0.002 0.998 0.000
Q12.0 Congenital cataract
0.002 0.998 0.000
Q61.2 Polycystic kidney, adult type
0.000 0.998 0.002
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour
0.000 0.998 0.002
D56.1 Beta thalassaemia
0.000 0.998 0.002
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)
0.000 0.998 0.002
C15.0 Cervical part of oesophagus
0.000 0.998 0.002
C77.2 Intra-abdominal lymph nodes
0.000 0.998 0.002
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.000 0.998 0.002
Q62.3 Other obstructive defects of renal pelvis and ureter
0.000 0.998 0.002
Q62.2 Congenital megaloureter
0.000 0.998 0.002
C21 Malignant neoplasm of anus and anal canal
0.000 0.998 0.002
G51.3 Clonic hemifacial spasm
0.002 0.998 0.000
I82.9 Embolism and thrombosis of unspecified vein
0.002 0.998 0.000
D56.9 Thalassaemia, unspecified
0.000 0.998 0.002
D56.8 Other thalassaemias
0.000 0.998 0.002
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]
0.000 0.998 0.002
D56.2 Delta-beta thalassaemia
0.000 0.998 0.002
D56.0 Alpha thalassaemia
0.000 0.998 0.002
C15.8 Overlapping lesion of oesophagus
0.000 0.998 0.002
C15.2 Abdominal part of oesophagus
0.000 0.998 0.002
G51.8 Other disorders of facial nerve
0.002 0.998 0.000
S92.70 Multiple fractures of foot (closed)
0.000 0.998 0.002
C26.8 Overlapping lesion of digestive system
0.000 0.998 0.002
C26.1 Spleen
0.000 0.998 0.002
F81.9 Developmental disorder of scholastic skills, unspecified
0.000 0.998 0.002
Q62.7 Congenital vesico-uretero-renal reflux
0.000 0.998 0.002
Q62.6 Malposition of ureter
0.000 0.998 0.002
Q62.4 Agenesis of ureter
0.000 0.998 0.002
Q62.0 Congenital hydronephrosis
0.000 0.998 0.002
C15.5 Lower third of oesophagus
0.000 0.998 0.002
D40.1 Testis
0.000 0.998 0.002
D48.5 Skin
0.000 0.998 0.002
Q64 Other congenital malformations of urinary system
0.000 0.998 0.002
D57.1 Sickle-cell anaemia without crisis
0.000 0.998 0.002
G51.9 Disorder of facial nerve, unspecified
0.002 0.998 0.000
K52.1 Toxic gastro-enteritis and colitis
0.001 0.998 0.000
Q61.8 Other cystic kidney diseases
0.000 0.998 0.002
Q61.1 Polycystic kidney, infantile type
0.000 0.998 0.002
U88 Agent resistant to multiple antibiotics
0.000 0.998 0.002
Q60-Q64 Congenital malformations of the urinary system
0.000 0.998 0.002
R47.8 Other and unspecified speech disturbances
0.002 0.998 0.000
R47.1 Dysarthria and anarthria
0.002 0.998 0.000
Z48.8 Other specified surgical follow-up care
0.002 0.998 0.000
D47.4 Osteomyelofibrosis
0.000 0.998 0.002
D57.8 Other sickle-cell disorders
0.000 0.998 0.001
D57.3 Sickle-cell trait
0.000 0.998 0.001
D57.2 Double heterozygous sickling disorders
0.000 0.998 0.001
D57.0 Sickle-cell anaemia with crisis
0.000 0.998 0.001
D58.2 Other haemoglobinopathies
0.000 0.998 0.002
Q61.4 Renal dysplasia
0.000 0.998 0.002
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.000 0.998 0.002
C15.1 Thoracic part of oesophagus
0.000 0.998 0.002
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.000 0.998 0.002
Q62.8 Other congenital malformations of ureter
0.000 0.998 0.002
T78.9 Adverse effect, unspecified
0.000 0.998 0.002
T78.0 Anaphylactic shock due to adverse food reaction
0.000 0.998 0.002
C15.4 Middle third of oesophagus
0.000 0.998 0.002
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.000 0.998 0.002
D55.9 Anaemia due to enzyme disorder, unspecified
0.000 0.998 0.001
D55.8 Other anaemias due to enzyme disorders
0.000 0.998 0.001
D55.3 Anaemia due to disorders of nucleotide metabolism
0.000 0.998 0.001
D55.2 Anaemia due to disorders of glycolytic enzymes
0.000 0.998 0.001
D55.1 Anaemia due to other disorders of glutathione metabolism
0.000 0.998 0.001
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency
0.000 0.998 0.001
D58.8 Other specified hereditary haemolytic anaemias
0.000 0.998 0.001
D58.1 Hereditary elliptocytosis
0.000 0.998 0.001
D58.0 Hereditary spherocytosis
0.000 0.998 0.002
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.998 0.002
Q62.1 Atresia and stenosis of ureter
0.000 0.998 0.001
Q64.7 Other congenital malformations of bladder and urethra
0.000 0.998 0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.998 0.002
Q64.4 Malformation of urachus
0.000 0.998 0.002
G51 Facial nerve disorders
0.002 0.998 0.000
L60.0 Ingrowing nail
0.002 0.998 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.998 0.002
I82 Other venous embolism and thrombosis
0.002 0.998 0.000
T78 Adverse effects, not elsewhere classified
0.000 0.998 0.002
R74.9 Abnormal level of unspecified serum enzyme
0.000 0.998 0.002
R74 Abnormal serum enzyme levels
0.000 0.998 0.002
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
0.000 0.998 0.001
G51.0 Bell's palsy
0.002 0.998 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.000 0.998 0.002
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)
0.000 0.998 0.002
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.998 0.001
C21.2 Cloacogenic zone
0.000 0.998 0.001
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.998 0.002
Q61.9 Cystic kidney disease, unspecified
0.000 0.998 0.001
R44.3 Hallucinations, unspecified
0.002 0.998 0.000
C26.9 Ill-defined sites within the digestive system
0.000 0.998 0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.000 0.998 0.002
L30.9 Dermatitis, unspecified
0.002 0.998 0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.000 0.998 0.001
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.998 0.002
R71 Abnormality of red blood cells
0.000 0.998 0.002
D58.9 Hereditary haemolytic anaemia, unspecified
0.000 0.998 0.001
E22.1 Hyperprolactinaemia
0.000 0.998 0.001
E27.2 Addisonian crisis
0.000 0.998 0.001
I82.3 Embolism and thrombosis of renal vein
0.001 0.998 0.000
I82.0 Budd-Chiari syndrome
0.001 0.998 0.000
J33.0 Polyp of nasal cavity
0.000 0.998 0.002
M54.2 Cervicalgia
0.000 0.998 0.002
Q44.6 Cystic disease of liver
0.000 0.998 0.002
Q64.9 Congenital malformation of urinary system, unspecified
0.000 0.998 0.001
Q64.8 Other specified congenital malformations of urinary system
0.000 0.998 0.001
Q64.6 Congenital diverticulum of bladder
0.000 0.998 0.001
Q64.5 Congenital absence of bladder and urethra
0.000 0.998 0.001
Q64.2 Congenital posterior urethral valves
0.000 0.998 0.001
Q64.1 Exstrophy of urinary bladder
0.000 0.998 0.001
Q64.0 Epispadias
0.000 0.998 0.001
E27 Other disorders of adrenal gland
0.000 0.998 0.002
M54.28 Cervicalgia-Sacral/sacrococ
0.000 0.998 0.001
G71 Primary disorders of muscles
0.000 0.998 0.001
C26.0 Intestinal tract, part unspecified
0.000 0.998 0.001
E22.0 Acromegaly and pituitary gigantism
0.000 0.998 0.001
T78.4 Allergy, unspecified
0.000 0.998 0.002
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)
0.000 0.998 0.001
Q63.2 Ectopic kidney
0.000 0.998 0.001
E22 Hyperfunction of pituitary gland
0.000 0.998 0.002
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.000 0.998 0.001
C25.1 Body of pancreas
0.000 0.998 0.001
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.998 0.001
E21.2 Other hyperparathyroidism
0.000 0.999 0.001
F20.9 Schizophrenia, unspecified
0.001 0.999 0.000
Q61.0 Congenital single renal cyst
0.000 0.999 0.001
Q63.1 Lobulated, fused and horseshoe kidney
0.000 0.999 0.001
C25 Malignant neoplasm of pancreas
0.000 0.999 0.001
Q63 Other congenital malformations of kidney
0.000 0.999 0.001
M54.23 Cervicalgia (Cervicothoracic region)
0.000 0.999 0.001
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.999 0.001
G51.4 Facial myokymia
0.001 0.999 0.000
G51.2 Melkersson's syndrome
0.001 0.999 0.000
G51.1 Geniculate ganglionitis
0.001 0.999 0.000
I82.1 Thrombophlebitis migrans
0.001 0.999 0.000
T78.8 Other adverse effects, not elsewhere classified
0.000 0.999 0.001
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)
0.000 0.999 0.001
S06.20 Diffuse brain injury (without open intracranial wound)
0.001 0.999 0.000
E85.4 Organ-limited amyloidosis
0.000 0.999 0.001
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.000 0.999 0.001
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)
0.000 0.999 0.001
Q60 Renal agenesis and other reduction defects of kidney
0.000 0.999 0.001
R77 Other abnormalities of plasma proteins
0.000 0.999 0.001
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)
0.000 0.999 0.001
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)
0.000 0.999 0.001
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)
0.000 0.999 0.001
C25.2 Tail of pancreas
0.000 0.999 0.001
E21.4 Other specified disorders of parathyroid gland
0.000 0.999 0.001
H18.4 Corneal degeneration
0.001 0.999 0.000
R73 Elevated blood glucose level
0.000 0.999 0.001
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.000 0.999 0.001
N94.1 Dyspareunia
0.000 0.999 0.001
R74.8 Abnormal levels of other serum enzymes
0.000 0.999 0.001
M54.27 Cervicalgia-Lumbosacral
0.000 0.999 0.001
M54.26 Cervicalgia-Lumbar
0.000 0.999 0.001
M54.25 Cervicalgia-Thoracolumbar
0.000 0.999 0.001
M54.24 Cervicalgia-Thoracic
0.000 0.999 0.001
M54.20 Cervicalgia-Mult site
0.000 0.999 0.001
E27.5 Adrenomedullary hyperfunction
0.000 0.999 0.001
E27.0 Other adrenocortical overactivity
0.000 0.999 0.001
Q60.2 Renal agenesis, unspecified
0.000 0.999 0.001
C25.7 Other parts of pancreas
0.000 0.999 0.001
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.999 0.001
G31.9 Degenerative disease of nervous system, unspecified
0.000 0.999 0.001
G71.9 Primary disorder of muscle, unspecified
0.000 0.999 0.001
G71.8 Other primary disorders of muscles
0.000 0.999 0.001
G71.2 Congenital myopathies
0.000 0.999 0.001
K86.8 Other specified diseases of pancreas
0.000 0.999 0.001
L20.8 Other atopic dermatitis
0.001 0.999 0.000
R09.0 Asphyxia
0.000 0.999 0.001
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]
0.000 0.999 0.001
R77.8 Other specified abnormalities of plasma proteins
0.000 0.999 0.001
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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