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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2425224
log Bayes Factor = 13.1546
Chromosome 20   position 35,002,849  (GRCh37) Explore rs2425224 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C44.3 Skin of other and unspecified parts of face
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
C44.4 Skin of scalp and neck
0.998 0.002 0.000
C44.6 Skin of upper limb, including shoulder
0.997 0.003 0.000
M20 Acquired deformities of fingers and toes
0.996 0.004 0.000
C44.1 Skin of eyelid, including canthus
0.995 0.005 0.000
M20.4 Other hammer toe(s) (acquired)
0.995 0.005 0.000
M20.1 Hallux valgus (acquired)
0.992 0.008 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.991 0.009 0.000
C43 Malignant melanoma of skin
0.990 0.010 0.000
C43.5 Malignant melanoma of trunk
0.985 0.015 0.000
C44.5 Skin of trunk
0.971 0.029 0.000
C44.7 Skin of lower limb, including hip
0.956 0.044 0.000
M20-M25 Other joint disorders
0.953 0.047 0.000
M23 Internal derangement of knee
0.928 0.072 0.000
C43.6 Malignant melanoma of upper limb, including shoulder
0.918 0.082 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.905 0.095 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.903 0.097 0.000
M24 Other specific joint derangements
0.898 0.102 0.000
M20.2 Hallux rigidus
0.888 0.112 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.835 0.165 0.000
M23.4 Loose body in knee
0.833 0.167 0.000
M24.1 Other articular cartilage disorders
0.802 0.198 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.800 0.199 0.000
C43.1 Malignant melanoma of eyelid, including canthus
0.795 0.205 0.000
M30 Polyarteritis nodosa and related conditions
0.791 0.209 0.000
M20.3 Other deformity of hallux (acquired)
0.785 0.215 0.000
C43.4 Malignant melanoma of scalp and neck
0.780 0.220 0.000
M34 Systemic sclerosis
0.772 0.228 0.000
M23.49 Loose body in knee-Unspec lig/men
0.757 0.243 0.000
M21 Other acquired deformities of limbs
0.756 0.244 0.000
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.741 0.259 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.739 0.261 0.000
C43.9 Malignant melanoma of skin, unspecified
0.730 0.270 0.000
M23.5 Chronic instability of knee
0.724 0.276 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
M20.0 Deformity of finger(s)
0.713 0.287 0.000
C43.8 Overlapping malignant melanoma of skin
0.710 0.290 0.000
C43.2 Malignant melanoma of ear and external auricular canal
0.710 0.290 0.000
C43.0 Malignant melanoma of lip
0.710 0.290 0.000
M23.9 Internal derangement of knee, unspecified
0.701 0.299 0.000
M32 Systemic lupus erythematosus
0.701 0.299 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.698 0.302 0.000
C44.0 Skin of lip
0.684 0.316 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.683 0.317 0.000
M24.0 Loose body in joint
0.676 0.324 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.675 0.325 0.000
M24.6 Ankylosis of joint
0.673 0.327 0.000
M33 Dermatopolymyositis
0.673 0.327 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.671 0.329 0.000
C43.3 Malignant melanoma of other and unspecified parts of face
0.667 0.333 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.667 0.333 0.000
M23.1 Discoid meniscus (congenital)
0.665 0.335 0.000
M24.17 Other articular cartilage disorders (Ankle and foot)
0.660 0.340 0.000
M24.5 Contracture of joint
0.658 0.342 0.000
M22 Disorders of patella
0.658 0.342 0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular
0.649 0.351 0.000
M24.9 Joint derangement, unspecified
0.644 0.356 0.000
M24.7 Protrusio acetabuli
0.644 0.356 0.000
C44.2 Skin of ear and external auricular canal
0.640 0.360 0.000
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)
0.636 0.364 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.636 0.364 0.000
M34.1 CR(E)ST syndrome
0.635 0.365 0.000
M23.8 Other internal derangements of knee
0.635 0.365 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.631 0.369 0.000
M30.0 Polyarteritis nodosa
0.629 0.371 0.000
M23.43 Loose body in knee-Med lig/oth men
0.622 0.378 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.619 0.381 0.000
M21.0 Valgus deformity, not elsewhere classified
0.616 0.384 0.000
M24.11 Other articular cartilage disorders (Shoulder region)
0.615 0.385 0.000
M24.2 Disorder of ligament
0.615 0.385 0.000
M23.0 Cystic meniscus
0.612 0.388 0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)
0.602 0.397 0.000
M23.47 Loose body in knee-Capsular lig
0.597 0.403 0.000
M23.46 Loose body in knee-O/unsp lat men
0.597 0.403 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.597 0.403 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.597 0.403 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.597 0.403 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.597 0.403 0.000
M23.40 Loose body in knee-Mult sites
0.597 0.403 0.000
M21.6 Other acquired deformities of ankle and foot
0.593 0.407 0.000
M21.3 Wrist or foot drop (acquired)
0.591 0.408 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.578 0.422 0.000
M24.19 Other articular cartilage disorders (Site unspecified)
0.575 0.425 0.000
M24.18 Other articular cartilage disorders (Other)
0.575 0.425 0.000
M24.14 Other articular cartilage disorders (Hand)
0.575 0.425 0.000
M24.12 Other articular cartilage disorders (Upper arm)
0.575 0.425 0.000
M24.10 Other articular cartilage disorders (Multiple sites)
0.575 0.425 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.571 0.429 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.567 0.433 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.567 0.433 0.000
M30.2 Juvenile polyarteritis
0.567 0.433 0.000
M22.8 Other disorders of patella
0.566 0.434 0.000
M34.9 Systemic sclerosis, unspecified
0.563 0.437 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.559 0.441 0.000
M34.8 Other forms of systemic sclerosis
0.557 0.443 0.000
M20.5 Other deformities of toe(s) (acquired)
0.556 0.444 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.554 0.446 0.000
M34.0 Progressive systemic sclerosis
0.554 0.446 0.000
M22.9 Disorder of patella, unspecified
0.549 0.451 0.000
M21.9 Acquired deformity of limb, unspecified
0.542 0.458 0.000
M21.8 Other specified acquired deformities of limbs
0.542 0.458 0.000
M21.7 Unequal limb length (acquired)
0.542 0.458 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.540 0.460 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.539 0.460 0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)
0.539 0.461 0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)
0.537 0.463 0.000
M21.4 Flat foot [pes planus] (acquired)
0.532 0.468 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.531 0.469 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.531 0.469 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.530 0.470 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.530 0.470 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.530 0.470 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.530 0.470 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.530 0.470 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.530 0.470 0.000
M24.51 Contracture of joint (Shoulder region)
0.524 0.476 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.520 0.480 0.000
M23.57 Chronic instability of knee (Capsular ligament)
0.519 0.481 0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)
0.519 0.481 0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)
0.519 0.481 0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.519 0.481 0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.519 0.481 0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.519 0.481 0.000
M23.50 Chronic instability of knee (Multiple sites)
0.519 0.481 0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)
0.519 0.481 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.514 0.485 0.000
M24.07 Loose body in joint (Ankle and foot)
0.514 0.486 0.000
M24.67 Ankylosis of joint (Ankle and foot)
0.511 0.489 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.509 0.491 0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)
0.503 0.497 0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)
0.503 0.497 0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)
0.503 0.497 0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.503 0.497 0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)
0.503 0.497 0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.503 0.497 0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.503 0.497 0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)
0.503 0.497 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.502 0.497 0.000
M32.8 Other forms of systemic lupus erythematosus
0.502 0.497 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.502 0.497 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.502 0.498 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.502 0.498 0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)
0.500 0.500 0.000
M22.3 Other derangements of patella
0.499 0.501 0.000
M21.2 Flexion deformity
0.499 0.501 0.000
M24.26 Disorder of ligament (Lower leg)
0.498 0.502 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.490 0.510 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.490 0.510 0.000
M36.3 Arthropathy in other blood disorders
0.490 0.510 0.000
M36.2 Haemophilic arthropathy
0.490 0.510 0.000
M36.1 Arthropathy in neoplastic disease
0.490 0.510 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.490 0.510 0.000
M24.02 Loose body in joint (Upper arm)
0.488 0.512 0.000
M33.2 Polymyositis
0.486 0.514 0.000
M24.09 Loose body in joint (Site unspecified)
0.485 0.515 0.000
M24.08 Loose body in joint (Other)
0.485 0.515 0.000
M24.06 Loose body in joint-Lower leg
0.485 0.515 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.485 0.515 0.000
M24.04 Loose body in joint (Hand)
0.485 0.515 0.000
M24.03 Loose body in joint (Forearm)
0.485 0.515 0.000
M24.01 Loose body in joint (Shoulder region)
0.485 0.515 0.000
M24.00 Loose body in joint (Multiple sites)
0.485 0.515 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.484 0.516 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.484 0.516 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.484 0.516 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.484 0.516 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.484 0.516 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.484 0.516 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.484 0.516 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.484 0.516 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.484 0.516 0.000
M24.69 Ankylosis of joint (Site unspecified)
0.482 0.517 0.000
M24.68 Ankylosis of joint (Other)
0.482 0.517 0.000
M24.66 Ankylosis of joint (Lower leg)
0.482 0.517 0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)
0.482 0.517 0.000
M24.64 Ankylosis of joint (Hand)
0.482 0.517 0.000
M24.63 Ankylosis of joint (Forearm)
0.482 0.517 0.000
M24.62 Ankylosis of joint (Upper arm)
0.482 0.517 0.000
M24.61 Ankylosis of joint (Shoulder region)
0.482 0.517 0.000
M24.60 Ankylosis of joint (Multiple sites)
0.482 0.517 0.000
M33.9 Dermatopolymyositis, unspecified
0.482 0.518 0.000
M33.0 Juvenile dermatomyositis
0.482 0.518 0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)
0.481 0.519 0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)
0.481 0.519 0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)
0.481 0.519 0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)
0.481 0.519 0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)
0.481 0.519 0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)
0.481 0.519 0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)
0.481 0.519 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.477 0.523 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.477 0.523 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.477 0.523 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.477 0.523 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.477 0.523 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.477 0.523 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.477 0.523 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.477 0.523 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.477 0.523 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.476 0.524 0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot
0.476 0.524 0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)
0.474 0.526 0.000
M24.56 Contracture of joint (Lower leg)
0.473 0.527 0.000
M40-M43 Deforming dorsopathies
0.472 0.528 0.000
M24.59 Contracture of joint (Site unspecified)
0.472 0.528 0.000
M24.58 Contracture of joint (Other)
0.472 0.528 0.000
M24.57 Contracture of joint (Ankle and foot)
0.472 0.528 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.472 0.528 0.000
M24.53 Contracture of joint (Forearm)
0.472 0.528 0.000
M24.52 Contracture of joint (Upper arm)
0.472 0.528 0.000
M24.50 Contracture of joint (Multiple sites)
0.472 0.528 0.000
M22.1 Recurrent subluxation of patella
0.472 0.528 0.000
M22.0 Recurrent dislocation of patella
0.472 0.528 0.000
M33.1 Other dermatomyositis
0.468 0.532 0.000
M45-M49 Spondylopathies
0.468 0.532 0.000
M24.79 Protrusio acetabuli-Site unspec
0.462 0.538 0.000
M24.78 Protrusio acetabuli-Other
0.462 0.538 0.000
M24.77 Protrusio acetabuli-Ankle/foot
0.462 0.538 0.000
M24.76 Protrusio acetabuli-Lower leg
0.462 0.538 0.000
M24.75 Protrusio acetabuli-Pelvic/thigh
0.462 0.538 0.000
M24.74 Protrusio acetabuli-Hand
0.462 0.538 0.000
M24.73 Protrusio acetabuli-Forearm
0.462 0.538 0.000
M24.72 Protrusio acetabuli-Upper arm
0.462 0.538 0.000
M24.71 Protrusio acetabuli-Shldr region
0.462 0.538 0.000
M24.70 Protrusio acetabuli-Mult sites
0.462 0.538 0.000
M24.99 Joint derangement, unspecified (Site unspecified)
0.462 0.538 0.000
M24.98 Joint derangement, unspecified (Other)
0.462 0.538 0.000
M24.97 Joint derangement, unspecified (Ankle and foot)
0.462 0.538 0.000
M24.96 Joint derangement, unspecified (Lower leg)
0.462 0.538 0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)
0.462 0.538 0.000
M24.94 Joint derangement, unspecified (Hand)
0.462 0.538 0.000
M24.93 Joint derangement, unspecified (Forearm)
0.462 0.538 0.000
M24.92 Joint derangement, unspecified (Upper arm)
0.462 0.538 0.000
M24.91 Joint derangement, unspecified (Shoulder region)
0.462 0.538 0.000
M24.90 Joint derangement, unspecified (Multiple sites)
0.462 0.538 0.000
M24.23 Disorder of ligament (Forearm)
0.457 0.543 0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)
0.456 0.544 0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)
0.456 0.544 0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp
0.456 0.544 0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn
0.456 0.544 0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.456 0.544 0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.456 0.544 0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.456 0.544 0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)
0.456 0.544 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.456 0.544 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.455 0.545 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.455 0.545 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.455 0.545 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.455 0.545 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.455 0.545 0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)
0.446 0.554 0.000
M86-M90 Other osteopathies
0.445 0.555 0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)
0.442 0.558 0.000
M21.08 Valgus deformity, not elsewhere classified (Other)
0.442 0.558 0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)
0.442 0.558 0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)
0.442 0.558 0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)
0.442 0.558 0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)
0.442 0.558 0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)
0.442 0.558 0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)
0.442 0.558 0.000
M24.29 Disorder of ligament (Site unspecified)
0.441 0.559 0.000
M24.28 Disorder of ligament (Other)
0.441 0.559 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.441 0.559 0.000
M24.22 Disorder of ligament (Upper arm)
0.441 0.559 0.000
M24.21 Disorder of ligament (Shoulder region)
0.441 0.559 0.000
M24.20 Disorder of ligament (Multiple sites)
0.441 0.559 0.000
M60-M63 Disorders of muscles
0.439 0.561 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.439 0.561 0.000
M23.07 Cystic meniscus-Capsular lig
0.439 0.561 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.439 0.561 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.439 0.561 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.439 0.561 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.439 0.561 0.000
M23.00 Cystic meniscus (Multiple sites)
0.439 0.561 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.439 0.561 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.438 0.562 0.000
M48 Other spondylopathies
0.435 0.565 0.000
M80-M85 Disorders of bone density and structure
0.434 0.566 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.433 0.567 0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.426 0.573 0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec
0.425 0.575 0.000
M21.68 Other acquired deformities of ankle and foot-Other
0.425 0.575 0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg
0.425 0.575 0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh
0.425 0.575 0.000
M21.64 Other acquired deformities of ankle and foot-Hand
0.425 0.575 0.000
M21.63 Other acquired deformities of ankle and foot-Forearm
0.425 0.575 0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm
0.425 0.575 0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region
0.425 0.575 0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites
0.425 0.575 0.000
M21.39 Wrist or foot drop (acquired)-Site unspec
0.424 0.576 0.000
M21.38 Wrist or foot drop (acquired)-Other
0.424 0.576 0.000
M21.36 Wrist or foot drop (acquired)-Lower leg
0.424 0.576 0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh
0.424 0.576 0.000
M21.34 Wrist or foot drop (acquired) (Hand)
0.424 0.576 0.000
M21.33 Wrist or foot drop (acquired) (Forearm)
0.424 0.576 0.000
M21.32 Wrist or foot drop (acquired)-Upper arm
0.424 0.576 0.000
M21.31 Wrist or foot drop (acquired)-Shldr region
0.424 0.576 0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)
0.424 0.576 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.421 0.579 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.421 0.579 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.420 0.579 0.000
M24.54 Contracture of joint (Hand)
0.419 0.581 0.000
M21.1 Varus deformity, not elsewhere classified
0.418 0.582 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.415 0.585 0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns
0.409 0.591 0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other
0.409 0.591 0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le
0.409 0.591 0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t
0.409 0.591 0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)
0.409 0.591 0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm
0.409 0.591 0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar
0.409 0.591 0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re
0.409 0.591 0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)
0.409 0.591 0.000
M43 Other deforming dorsopathies
0.409 0.591 0.000
M35 Other systemic involvement of connective tissue
0.409 0.591 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.407 0.593 0.000
M41 Scoliosis
0.397 0.603 0.000
M31 Other necrotising vasculopathies
0.396 0.604 0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)
0.395 0.605 0.000
M24.24 Disorder of ligament (Hand)
0.389 0.610 0.000
M21.79 Unequal limb length (acquired) (Site unspecified)
0.389 0.611 0.000
M21.78 Unequal limb length (acquired)-Other
0.389 0.611 0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)
0.389 0.611 0.000
M21.76 Unequal limb length (acquired) (Lower leg)
0.389 0.611 0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)
0.389 0.611 0.000
M21.74 Unequal limb length (acquired) (Hand)
0.389 0.611 0.000
M21.73 Unequal limb length (acquired) (Forearm)
0.389 0.611 0.000
M21.72 Unequal limb length (acquired) (Upper arm)
0.389 0.611 0.000
M21.71 Unequal limb length (acquired)-Shldr region
0.389 0.611 0.000
M21.70 Unequal limb length (acquired) (Multiple sites)
0.389 0.611 0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)
0.389 0.611 0.000
M21.88 Other specified acquired deformities of limbs-Other
0.389 0.611 0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)
0.389 0.611 0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)
0.389 0.611 0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)
0.389 0.611 0.000
M21.84 Other specified acquired deformities of limbs (Hand)
0.389 0.611 0.000
M21.83 Other specified acquired deformities of limbs (Forearm)
0.389 0.611 0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)
0.389 0.611 0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)
0.389 0.611 0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)
0.389 0.611 0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)
0.389 0.611 0.000
M21.98 Acquired deformity of limb, unspecified-Other
0.389 0.611 0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)
0.389 0.611 0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)
0.389 0.611 0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)
0.389 0.611 0.000
M21.94 Acquired deformity of limb, unspecified (Hand)
0.389 0.611 0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)
0.389 0.611 0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)
0.389 0.611 0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)
0.389 0.611 0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)
0.389 0.611 0.000
M62 Other disorders of muscle
0.386 0.614 0.000
M00-M03 Infectious arthropathies
0.386 0.614 0.000
M46 Other inflammatory spondylopathies
0.384 0.616 0.000
M21.49 Flat foot [pes planus] (acquired)-Site unspec
0.381 0.618 0.000
M21.48 Flat foot [pes planus] (acquired)-Other
0.381 0.618 0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg
0.381 0.618 0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh
0.381 0.618 0.000
M21.44 Flat foot [pes planus] (acquired)-Hand
0.381 0.618 0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm
0.381 0.618 0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm
0.381 0.618 0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region
0.381 0.618 0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites
0.381 0.618 0.000
M80 Osteoporosis with pathological fracture
0.379 0.621 0.000
M43.1 Spondylolisthesis
0.374 0.626 0.000
M91-M94 Chondropathies
0.374 0.626 0.000
M23.3 Other meniscus derangements
0.374 0.626 0.000
M40 Kyphosis and lordosis
0.373 0.627 0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot
0.371 0.629 0.000
M88 Paget's disease of bone [osteitis deformans]
0.364 0.636 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.363 0.637 0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites
0.360 0.639 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.358 0.642 0.000
M21.29 Flexion deformity (Site unspecified)
0.358 0.642 0.000
M21.28 Flexion deformity (Other)
0.358 0.642 0.000
M21.25 Flexion deformity (Pelvic region and thigh)
0.358 0.642 0.000
M21.23 Flexion deformity (Forearm)
0.358 0.642 0.000
M21.22 Flexion deformity (Upper arm)
0.358 0.642 0.000
M21.21 Flexion deformity (Shoulder region)
0.358 0.642 0.000
M21.20 Flexion deformity (Multiple sites)
0.358 0.642 0.000
M21.27 Flexion deformity (Ankle and foot)
0.356 0.644 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.355 0.645 0.000
M21.26 Flexion deformity (Lower leg)
0.353 0.647 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.352 0.648 0.000
M62.8 Other specified disorders of muscle
0.348 0.652 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.346 0.654 0.000
M41.9 Scoliosis, unspecified
0.343 0.657 0.000
M90 Osteopathies in diseases classified elsewhere
0.342 0.658 0.000
M89 Other disorders of bone
0.339 0.661 0.000
M42 Spinal osteochondrosis
0.339 0.661 0.000
M22.10 Recurrent subluxation of patella, unspecified knee
0.338 0.661 0.000
M49 Spondylopathies in diseases classified elsewhere
0.334 0.666 0.000
M87 Osteonecrosis
0.333 0.667 0.000
M85 Other disorders of bone density and structure
0.331 0.669 0.000
M86 Osteomyelitis
0.331 0.669 0.000
M47 Spondylosis
0.331 0.669 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.324 0.676 0.000
M21.24 Flexion deformity (Hand)
0.323 0.677 0.000
M60 Myositis
0.322 0.678 0.000
M22.2 Patellofemoral disorders
0.321 0.679 0.000
M43.6 Torticollis
0.319 0.681 0.000
M46.4 Discitis, unspecified
0.317 0.682 0.000
M62.88 Other specified disorders of muscle (Other)
0.317 0.683 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.315 0.685 0.000
M61 Calcification and ossification of muscle
0.315 0.685 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.312 0.688 0.000
M48.9 Spondylopathy, unspecified
0.312 0.688 0.000
M48.8 Other specified spondylopathies
0.312 0.688 0.000
M48.4 Fatigue fracture of vertebra
0.312 0.688 0.000
M48.3 Traumatic spondylopathy
0.312 0.688 0.000
M48.2 Kissing spine
0.312 0.688 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.312 0.688 0.000
M84 Disorders of continuity of bone
0.311 0.689 0.000
M83 Adult osteomalacia
0.311 0.689 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.310 0.690 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.306 0.694 0.000
M88.9 Paget's disease of bone, unspecified
0.305 0.695 0.000
M82 Osteoporosis in diseases classified elsewhere
0.305 0.695 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.303 0.697 0.000
M40.2 Other and unspecified kyphosis
0.302 0.698 0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)
0.300 0.700 0.000
M21.18 Varus deformity, not elsewhere classified (Other)
0.300 0.700 0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)
0.300 0.700 0.000
M21.14 Varus deformity, not elsewhere classified (Hand)
0.300 0.700 0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)
0.300 0.700 0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)
0.300 0.700 0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)
0.300 0.700 0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)
0.300 0.700 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.299 0.701 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.298 0.702 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.298 0.702 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.298 0.702 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.298 0.702 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.298 0.702 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.298 0.702 0.000
M00 Pyogenic arthritis
0.297 0.703 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.294 0.706 0.000
M81 Osteoporosis without pathological fracture
0.294 0.706 0.000
M43.9 Deforming dorsopathy, unspecified
0.293 0.706 0.000
M43.8 Other specified deforming dorsopathies
0.293 0.706 0.000
M43.5 Other recurrent vertebral subluxation
0.293 0.706 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.293 0.706 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.293 0.706 0.000
M43.2 Other fusion of spine
0.293 0.706 0.000
M48.0 Spinal stenosis
0.294 0.706 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.293 0.707 0.000
M35.8 Other specified systemic involvement of connective tissue
0.293 0.707 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.293 0.707 0.000
M35.5 Multifocal fibrosclerosis
0.293 0.707 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.293 0.707 0.000
M35.2 Behcet's disease
0.293 0.707 0.000
M45 Ankylosing spondylitis
0.289 0.711 0.000
M43.12 Spondylolisthesis (Cervical region)
0.287 0.713 0.000
M94 Other disorders of cartilage
0.286 0.714 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.286 0.714 0.000
M41.8 Other forms of scoliosis
0.285 0.715 0.000
M41.5 Other secondary scoliosis
0.285 0.715 0.000
M41.4 Neuromuscular scoliosis
0.285 0.715 0.000
M41.3 Thoracogenic scoliosis
0.285 0.715 0.000
M41.2 Other idiopathic scoliosis
0.285 0.715 0.000
M41.1 Juvenile idiopathic scoliosis
0.285 0.715 0.000
M41.0 Infantile idiopathic scoliosis
0.285 0.715 0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.285 0.715 0.000
M31.9 Necrotising vasculopathy, unspecified
0.284 0.716 0.000
M31.8 Other specified necrotising vasculopathies
0.284 0.716 0.000
M31.7 Microscopic polyangiitis
0.284 0.716 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.284 0.716 0.000
M31.2 Lethal midline granuloma
0.284 0.716 0.000
M31.1 Thrombotic microangiopathy
0.284 0.716 0.000
M31.0 Hypersensitivity angiitis
0.284 0.716 0.000
M65-M68 Disorders of synovium and tendon
0.283 0.717 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.282 0.718 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.279 0.721 0.000
M62.9 Disorder of muscle, unspecified
0.277 0.723 0.000
M62.6 Muscle strain
0.277 0.723 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.277 0.723 0.000
M62.4 Contracture of muscle
0.277 0.723 0.000
M62.3 Immobility syndrome (paraplegic)
0.277 0.723 0.000
M62.2 Ischaemic infarction of muscle
0.277 0.723 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.277 0.723 0.000
M62.0 Diastasis of muscle
0.277 0.723 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.277 0.723 0.000
M02 Reactive arthropathies
0.277 0.723 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.277 0.723 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.276 0.724 0.000
M46.8 Other specified inflammatory spondylopathies
0.275 0.724 0.000
M46.5 Other infective spondylopathies
0.275 0.724 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.275 0.724 0.000
M46.2 Osteomyelitis of vertebra
0.275 0.724 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.275 0.724 0.000
M46.0 Spinal enthesopathy
0.275 0.724 0.000
M48.09 Spinal stenosis (Site unspecified)
0.276 0.724 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.275 0.725 0.000
M35.7 Hypermobility syndrome
0.272 0.727 0.000
M80.8 Other osteoporosis with pathological fracture
0.272 0.728 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.272 0.728 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.272 0.728 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.272 0.728 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.270 0.730 0.000
M46.46 Discitis, unspecified (Lumbar region)
0.270 0.730 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.269 0.731 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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