TreeWAS – Variant ID: rs2447820

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.021	0.979	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.014	0.986	0.000
Y48 Anaesthetics and therapeutic gases	0.014	0.986	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.014	0.986	0.000
Y48.4 Anaesthetic, unspecified	0.013	0.987	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.013	0.987	0.000
Y42.7 Androgens and anabolic congeners	0.013	0.987	0.000
Y49.2 Other and unspecified antidepressants	0.012	0.987	0.000
Y48.3 Local anaesthetics	0.012	0.988	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.012	0.988	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.012	0.988	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.011	0.989	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.011	0.989	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.011	0.989	0.000
Y48.2 Other and unspecified general anaesthetics	0.011	0.989	0.000
Y58 Bacterial vaccines	0.011	0.989	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.011	0.989	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.010	0.989	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.010	0.990	0.000
Y59 Other and unspecified vaccines and biological substances	0.010	0.990	0.000
Y48.5 Therapeutic gases	0.010	0.990	0.000
Y48.1 Parenteral anaesthetics	0.010	0.990	0.000
Y48.0 Inhaled anaesthetics	0.010	0.990	0.000
Y42.9 Other and unspecified hormone antagonists	0.010	0.990	0.000
Y42.4 Oral contraceptives	0.010	0.990	0.000
Y42.2 Antithyroid drugs	0.010	0.990	0.000
Y42.1 Thyroid hormones and substitutes	0.010	0.990	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.010	0.990	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.010	0.990	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.009	0.990	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.009	0.991	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.009	0.991	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.009	0.991	0.000
Y57 Other and unspecified drugs and medicaments	0.009	0.991	0.000
J02.9 Acute pharyngitis, unspecified	0.009	0.991	0.000
K70.4 Alcoholic hepatic failure	0.009	0.991	0.000
Y45.8 Other analgesics and antipyretics	0.009	0.991	0.000
Y49.9 Psychotropic drug, unspecified	0.009	0.991	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.009	0.991	0.000
Y49.7 Psychostimulants with abuse potential	0.009	0.991	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.009	0.991	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.009	0.991	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.009	0.991	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.009	0.991	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.009	0.991	0.000
Y52 Agents primarily affecting the cardiovascular system	0.009	0.991	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.009	0.991	0.000
Y54.4 Loop [high-ceiling] diuretics	0.009	0.991	0.000
Y45.0 Opioids and related analgesics	0.009	0.991	0.000
Y58.0 BCG vaccine	0.009	0.991	0.000
K70 Alcoholic liver disease	0.009	0.991	0.000
Y56.9 Topical agent, unspecified	0.008	0.991	0.000
Y56.8 Other topical agents	0.008	0.991	0.000
Y56.7 Dental drugs, topically applied	0.008	0.991	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.008	0.991	0.000
Y56.5 Ophthalmological drugs and preparations	0.008	0.991	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.008	0.991	0.000
Y56.3 Emollients, demulcents and protectants	0.008	0.991	0.000
Y56.2 Local astringents and local detergents	0.008	0.991	0.000
Y56.1 Antipruritics	0.008	0.991	0.000
Y44 Agents primarily affecting blood constituents	0.008	0.991	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.008	0.991	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.008	0.992	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.008	0.992	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.008	0.992	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.008	0.992	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.008	0.992	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.008	0.992	0.000
Y51.0 Anticholinesterase agents	0.008	0.992	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.008	0.992	0.000
Y54.8 Agents affecting uric acid metabolism	0.008	0.992	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.008	0.992	0.000
Y55.5 Anticommon cold drugs	0.008	0.992	0.000
Y55.4 Expectorants	0.008	0.992	0.000
Y55.3 Antitussives	0.008	0.992	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.008	0.992	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.008	0.992	0.000
Y55.0 Oxytocic drugs	0.008	0.992	0.000
K70.9 Alcoholic liver disease, unspecified	0.008	0.992	0.000
Y59.3 Immunoglobulin	0.008	0.992	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.008	0.992	0.000
Y45.5 4-Aminophenol derivatives	0.008	0.992	0.000
Y45.4 Antirheumatics	0.008	0.992	0.000
Y57.5 X-ray contrast media	0.008	0.992	0.000
Y54.3 Benzothiadiazine derivatives	0.008	0.992	0.000
Y58.9 Other and unspecified bacterial vaccines	0.008	0.992	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.008	0.992	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.008	0.992	0.000
Y58.5 Diphtheria vaccine	0.008	0.992	0.000
Y58.4 Tetanus vaccine	0.008	0.992	0.000
Y58.3 Plague vaccine	0.008	0.992	0.000
Y58.2 Cholera vaccine	0.008	0.992	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.008	0.992	0.000
Y54.9 Mineral salts, not elsewhere classified	0.008	0.992	0.000
Y54.7 Agents affecting calcification	0.008	0.992	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.008	0.992	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.008	0.992	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.008	0.992	0.000
Y54.0 Mineralocorticoids	0.008	0.992	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.008	0.992	0.000
Y40 Systemic antibiotics	0.008	0.992	0.000
C78.7 Secondary malignant neoplasm of liver	0.008	0.992	0.000
Y59.9 Vaccine or biological substance, unspecified	0.007	0.992	0.000
Y59.8 Other specified vaccines and biological substances	0.007	0.992	0.000
Y59.2 Protozoal vaccines	0.007	0.992	0.000
Y59.1 Rickettsial vaccines	0.007	0.992	0.000
Y59.0 Viral vaccines	0.007	0.992	0.000
Y49.5 Other antipsychotics and neuroleptics	0.007	0.992	0.000
Y45.1 Salicylates	0.007	0.993	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.007	0.993	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.007	0.993	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.007	0.993	0.000
Y47.4 Bromine compounds	0.007	0.993	0.000
Y47.3 Paraldehyde	0.007	0.993	0.000
Y47.2 Chloral derivatives	0.007	0.993	0.000
Y47.1 Benzodiazepines	0.007	0.993	0.000
Y47.0 Barbiturates, not elsewhere classified	0.007	0.993	0.000
Y50.9 Central nervous system stimulant, unspecified	0.007	0.993	0.000
Y50.8 Other central nervous system stimulants	0.007	0.993	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.007	0.993	0.000
Y50.1 Opioid receptor antagonists	0.007	0.993	0.000
Y50.0 Analeptics	0.007	0.993	0.000
Y42.5 Other oestrogens and progestogens	0.007	0.993	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
K70.1 Alcoholic hepatitis	0.007	0.993	0.000
Y46.8 Antispasticity drugs	0.007	0.993	0.000
Y46.7 Anti-Parkinsonism drugs	0.007	0.993	0.000
Y46.6 Other and unspecified antiepileptics	0.007	0.993	0.000
Y46.5 Valproic acid	0.007	0.993	0.000
Y46.3 Deoxybarbiturates	0.007	0.993	0.000
Y46.2 Hydantoin derivatives	0.007	0.993	0.000
Y46.1 Oxazolidinediones	0.007	0.993	0.000
Y46.0 Succinimides	0.007	0.993	0.000
Y57.7 Vitamins, not elsewhere classified	0.007	0.993	0.000
Y57.6 Other diagnostic agents	0.007	0.993	0.000
Y57.4 Pharmaceutical excipients	0.007	0.993	0.000
Y57.3 Alcohol deterrents	0.007	0.993	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.007	0.993	0.000
Y57.1 Lipotropic drugs	0.007	0.993	0.000
Y57.0 Appetite depressants [anorectics]	0.007	0.993	0.000
Y45.2 Propionic acid derivatives	0.007	0.993	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.007	0.993	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.007	0.993	0.000
Y53.7 Emetics	0.007	0.993	0.000
Y53.6 Antidiarrhoeal drugs	0.007	0.993	0.000
Y53.5 Digestants	0.007	0.993	0.000
Y53.3 Saline and osmotic laxatives	0.007	0.993	0.000
Y53.2 Stimulant laxatives	0.007	0.993	0.000
Y53.0 Histamine H2-receptor antagonists	0.007	0.993	0.000
Y57.8 Other drugs and medicaments	0.007	0.993	0.000
Y53.4 Other laxatives	0.007	0.993	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
Y52.7 Peripheral vasodilators	0.007	0.993	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.007	0.993	0.000
Y54.5 Other diuretics	0.007	0.993	0.000
K70.3 Alcoholic cirrhosis of liver	0.007	0.993	0.000
Y46.4 Iminostilbenes	0.006	0.993	0.000
O32.1 Maternal care for breech presentation	0.007	0.993	0.000
Y44.5 Thrombolytic drugs	0.006	0.993	0.000
Y40.7 Antifungal antibiotics, systemically used	0.006	0.993	0.000
K72.9 Hepatic failure, unspecified	0.007	0.993	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.006	0.994	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.006	0.994	0.000
Y44.7 Plasma substitutes	0.006	0.994	0.000
Y44.6 Natural blood and blood products	0.006	0.994	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.006	0.994	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.006	0.994	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.006	0.994	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
Y40.3 Macrolides	0.006	0.994	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.006	0.994	0.000
K70.0 Alcoholic fatty liver	0.006	0.994	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.994	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
Y41.5 Antiviral drugs	0.006	0.994	0.000
Y41.4 Anthelminthics	0.006	0.994	0.000
Y41.3 Other antiprotozoal drugs	0.006	0.994	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
Y41.1 Antimycobacterial drugs	0.006	0.994	0.000
Y41.0 Sulphonamides	0.006	0.994	0.000
Y40.6 Rifamycins	0.006	0.994	0.000
Y40.5 Aminoglycosides	0.006	0.994	0.000
Y40.4 Tetracyclines	0.006	0.994	0.000
Y40.2 Chloramphenicol group	0.006	0.994	0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.006	0.994	0.000
K70-K77 Diseases of liver	0.006	0.994	0.000
J02 Acute pharyngitis	0.006	0.994	0.000
K72 Hepatic failure, not elsewhere classified	0.006	0.994	0.000
Y52.1 Calcium-channel blockers	0.005	0.994	0.000
Y40.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.005	0.995	0.000
Y43 Primarily systemic agents	0.005	0.995	0.000
Y40.8 Other systemic antibiotics	0.005	0.995	0.000
K76 Other diseases of liver	0.005	0.995	0.000
K76.6 Portal hypertension	0.005	0.995	0.000
C78.2 Secondary malignant neoplasm of pleura	0.005	0.995	0.000
D05.1 Intraductal carcinoma in situ	0.000	0.995	0.005
Y57.9 Drug or medicament, unspecified	0.005	0.995	0.000
Y44.2 Anticoagulants	0.005	0.995	0.000
Y40.0 Penicillins	0.005	0.995	0.000
J02.0 Streptococcal pharyngitis	0.005	0.995	0.000
K75 Other inflammatory liver diseases	0.005	0.995	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.995	0.000
Y43.1 Antineoplastic antimetabolites	0.005	0.995	0.000
I10-I15 Hypertensive diseases	0.004	0.995	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.004	0.995	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.004	0.996	0.000
K75.8 Other specified inflammatory liver diseases	0.004	0.996	0.000
K77 Liver disorders in diseases classified elsewhere	0.004	0.996	0.000
K71 Toxic liver disease	0.004	0.996	0.000
K72.1 Chronic hepatic failure	0.004	0.996	0.000
K76.9 Liver disease, unspecified	0.004	0.996	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.004	0.996	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.004	0.996	0.000
N21.0 Calculus in bladder	0.000	0.996	0.004
Y40.1 Cefalosporins and other -lactam antibiotics	0.004	0.996	0.000
Y43.9 Primarily systemic agent, unspecified	0.004	0.996	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.004	0.996	0.000
Y43.6 Enzymes, not elsewhere classified	0.004	0.996	0.000
Y43.5 Acidifying and alkalising agents	0.004	0.996	0.000
Y43.2 Antineoplastic natural products	0.004	0.996	0.000
K75.0 Abscess of liver	0.004	0.996	0.000
K76.5 Hepatic veno-occlusive disease	0.004	0.996	0.000
K76.4 Peliosis hepatis	0.004	0.996	0.000
K76.3 Infarction of liver	0.004	0.996	0.000
K76.2 Central haemorrhagic necrosis of liver	0.004	0.996	0.000
K76.1 Chronic passive congestion of liver	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.996	0.001
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.004	0.996	0.000
Y43.4 Immunosuppressive agents	0.004	0.996	0.000
I15 Secondary hypertension	0.003	0.996	0.000
K76.7 Hepatorenal syndrome	0.003	0.996	0.000
K73 Chronic hepatitis, not elsewhere classified	0.003	0.996	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.003	0.996	0.000
K75.2 Nonspecific reactive hepatitis	0.003	0.996	0.000
K75.1 Phlebitis of portal vein	0.003	0.996	0.000
I13 Hypertensive heart and renal disease	0.003	0.996	0.000
C43.5 Malignant melanoma of trunk	0.003	0.997	0.000
C43.4 Malignant melanoma of scalp and neck	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.003	0.997	0.000
K71.9 Toxic liver disease, unspecified	0.003	0.997	0.000
K71.8 Toxic liver disease with other disorders of liver	0.003	0.997	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.003	0.997	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.003	0.997	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.003	0.997	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.003	0.997	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.003	0.997	0.000
K71.2 Toxic liver disease with acute hepatitis	0.003	0.997	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.003	0.997	0.000
K71.0 Toxic liver disease with cholestasis	0.003	0.997	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.003	0.997	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
O30.0 Twin pregnancy	0.003	0.997	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.003	0.997	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.003	0.997	0.000
I11 Hypertensive heart disease	0.003	0.997	0.000
K75.4 Autoimmune hepatitis	0.003	0.997	0.000
K76.8 Other specified diseases of liver	0.003	0.997	0.000
C43 Malignant melanoma of skin	0.003	0.997	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.003	0.997	0.000
O70.2 Third degree perineal laceration during delivery	0.003	0.997	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.003	0.997	0.000
I42.9 Cardiomyopathy, unspecified	0.003	0.997	0.000
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
J31.0 Chronic rhinitis	0.003	0.997	0.000
I15.1 Hypertension secondary to other renal disorders	0.003	0.997	0.000
K74 Fibrosis and cirrhosis of liver	0.003	0.997	0.000
I15.9 Seconday hypertension, unspecified	0.003	0.997	0.000
I15.8 Other secondary hypertension	0.003	0.997	0.000
I15.2 Hypertension secondary to endocrine disorders	0.003	0.997	0.000
I15.0 Renovascular hypertension	0.003	0.997	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.003	0.997	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.003	0.997	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.003	0.997	0.000
K72.0 Acute and subacute hepatic failure	0.002	0.997	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.003	0.997	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.003	0.997	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.003	0.997	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.003	0.997	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.003	0.997	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.000	0.997	0.003
C78.4 Secondary malignant neoplasm of small intestine	0.003	0.997	0.000
I42.8 Other cardiomyopathies	0.003	0.997	0.000
Z37.2 Twins, both liveborn	0.003	0.997	0.000
C43.8 Overlapping malignant melanoma of skin	0.003	0.997	0.000
C43.0 Malignant melanoma of lip	0.003	0.997	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
K73.9 Chronic hepatitis, unspecified	0.002	0.997	0.000
C78.0 Secondary malignant neoplasm of lung	0.003	0.997	0.000
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.002	0.997	0.000
C20 Malignant neoplasm of rectum	0.000	0.997	0.003
K74.0 Hepatic fibrosis	0.002	0.997	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.002	0.998	0.000
I42 Cardiomyopathy	0.002	0.998	0.000
K74.4 Secondary biliary cirrhosis	0.002	0.998	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.002	0.998	0.000
K74.1 Hepatic sclerosis	0.002	0.998	0.000
E87.7 Fluid overload	0.002	0.998	0.000
Z00.6 Examination for normal comparison and control in clinical research programme	0.002	0.998	0.000
K75.9 Inflammatory liver disease, unspecified	0.002	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
C43.9 Malignant melanoma of skin, unspecified	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.002	0.998	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
L89.9 Decubitus ulcer and pressure area, unspecified	0.002	0.998	0.000
Z00.0 General medical examination	0.002	0.998	0.000
N21 Calculus of lower urinary tract	0.000	0.998	0.002
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.002	0.998	0.000
K25 Gastric ulcer	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.002	0.998	0.000
I42.5 Other restrictive cardiomyopathy	0.002	0.998	0.000
I42.4 Endocardial fibroelastosis	0.002	0.998	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.002	0.998	0.000
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.001	0.998	0.000
Z00.5 Examination of potential donor of organ and tissue	0.002	0.998	0.000
J00 Acute nasopharyngitis [common cold]	0.002	0.998	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
K25.5 Chronic or unspecified with perforation	0.002	0.998	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.002	0.998	0.000
B37.3 Candidiasis of vulva and vagina	0.002	0.998	0.000
I42.6 Alcoholic cardiomyopathy	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.998	0.001
I72.3 Aneurysm of iliac artery	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.002	0.998	0.000
K25.4 Chronic or unspecified with haemorrhage	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.002	0.998	0.000
N85.4 Malposition of uterus	0.002	0.998	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.998	0.002
M51.9 Intervertebral disk disorder, unspecified	0.002	0.998	0.000
O32.3 Maternal care for face, brow and chin presentation	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
N21.1 Calculus in urethra	0.000	0.998	0.002
N21.9 Calculus of lower urinary tract, unspecified	0.000	0.998	0.002
N21.8 Other lower urinary tract calculus	0.000	0.998	0.002
O32.2 Maternal care for transverse and oblique lie	0.002	0.998	0.000
I12 Hypertensive renal disease	0.001	0.998	0.001
J00-J06 Acute upper respiratory infections	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.002	0.998	0.000
K65.8 Other peritonitis	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.002	0.998	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.002	0.998	0.000
K25.2 Acute with both haemorrhage and perforation	0.002	0.998	0.000
K25.1 Acute with perforation	0.002	0.998	0.000
K25.0 Acute with haemorrhage	0.002	0.998	0.000
O30 Multiple gestation	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.998	0.002
O32.9 Maternal care for malpresentation of foetus, unspecified	0.001	0.998	0.000
O32.6 Maternal care for compound presentation	0.001	0.998	0.000
Z00.4 General psychiatric examination, not elsewhere classified	0.002	0.998	0.000
J01 Acute sinusitis	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
C77.2 Intra-abdominal lymph nodes	0.002	0.998	0.000
Z00.8 Other general examinations	0.001	0.998	0.000
Z00.3 Examination for adolescent development state	0.001	0.998	0.000
Z00.2 Examination for period of rapid growth in childhood	0.001	0.998	0.000
Z00.1 Routine child health examination	0.001	0.998	0.000
K08.3 Retained dental root	0.000	0.998	0.002
C43.3 Malignant melanoma of other and unspecified parts of face	0.001	0.998	0.000
K25.7 Chronic without haemorrhage or perforation	0.002	0.998	0.000
K90.0 Coeliac disease	0.002	0.998	0.000
J03 Acute tonsillitis	0.001	0.998	0.001
J01.0 Acute maxillary sinusitis	0.001	0.998	0.000
N28.8 Other specified disorders of kidney and ureter	0.002	0.998	0.000
I72 Other aneurysm	0.002	0.998	0.000
I42.0 Dilated cardiomyopathy	0.002	0.998	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.002	0.998	0.000
O32.4 Maternal care for high head at term	0.001	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.001	0.998	0.000
B37.4 Candidiasis of other urogenital sites	0.001	0.998	0.000
Z37.1 Single stillbirth	0.001	0.998	0.000
M51 Other intervertebral disk disorders	0.002	0.998	0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.001	0.998	0.000
H57.1 Ocular pain	0.001	0.998	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.000	0.998	0.001
M51.3 Other specified intervertebral disk degeneration	0.001	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.001	0.998	0.000
B37.8 Candidiasis of other sites	0.001	0.999	0.000
H53.8 Other visual disturbances	0.000	0.999	0.001
O30.9 Multiple gestation, unspecified	0.001	0.999	0.000
O30.8 Other multiple gestation	0.001	0.999	0.000
O30.2 Quadruplet pregnancy	0.001	0.999	0.000
O30.1 Triplet pregnancy	0.001	0.999	0.000
J01.9 Acute sinusitis, unspecified	0.001	0.999	0.000
J01.8 Other acute sinusitis	0.001	0.999	0.000
J01.4 Acute pansinusitis	0.001	0.999	0.000
J01.3 Acute sphenoidal sinusitis	0.001	0.999	0.000
J01.2 Acute ethmoidal sinusitis	0.001	0.999	0.000
J01.1 Acute frontal sinusitis	0.001	0.999	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.999	0.001
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.001	0.999	0.000
M87.9 Osteonecrosis, unspecified	0.001	0.999	0.000
O32.8 Maternal care for other malpresentation of foetus	0.001	0.999	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.001	0.999	0.000
T20.2 Burn of second degree of head and neck	0.001	0.999	0.000
B37.2 Candidiasis of skin and nail	0.001	0.999	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.001	0.999	0.001
J03.0 Streptococcal tonsillitis	0.001	0.999	0.001
Z37.3 Twins, one liveborn and one stillborn	0.001	0.999	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.999	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.999	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.999	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.001	0.999	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.001	0.999	0.000
E87.0 Hyperosmolality and hypernatraemia	0.001	0.999	0.000
I72.2 Aneurysm of renal artery	0.001	0.999	0.000
Z37 Outcome of delivery	0.001	0.999	0.000
D41.4 Bladder	0.001	0.999	0.000
E87.5 Hyperkalaemia	0.001	0.999	0.000
H90.0 Conductive hearing loss, bilateral	0.000	0.999	0.001
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.001	0.999	0.000
I72.9 Aneurysm of unspecified site	0.001	0.999	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.001	0.999	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.001	0.999	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.001	0.999	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.001	0.999	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.001	0.999	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.001	0.999	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.001	0.999	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.001	0.999	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.001	0.999	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.001	0.999	0.000
J05.0 Acute obstructive laryngitis [croup]	0.001	0.999	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.001	0.999	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.001	0.999	0.000
K29.1 Other acute gastritis	0.001	0.999	0.000
X41.9 Unspecified place	0.001	0.999	0.000
D33.3 Cranial nerves	0.000	0.999	0.001
B37 Candidiasis	0.001	0.999	0.000
O32.0 Maternal care for unstable lie	0.001	0.999	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.001	0.999	0.000
Z36.1 Antenatal screening for raised alphafetoprotein level	0.001	0.999	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.999	0.000
K61.0 Anal abscess	0.001	0.999	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.001	0.999	0.000
Z37.9 Outcome of delivery unspecified	0.001	0.999	0.000
Z37.7 Other multiple births, all stillborn	0.001	0.999	0.000
Z37.6 Other multiple births, some liveborn	0.001	0.999	0.000
Z37.5 Other multiple births, all liveborn	0.001	0.999	0.000
Z37.4 Twins, both stillborn	0.001	0.999	0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.001	0.999	0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.001	0.999	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.001	0.999	0.000
G58.8 Other specified mononeuropathies	0.001	0.999	0.000
H74.0 Tympanosclerosis	0.001	0.999	0.000
K25.3 Acute without haemorrhage or perforation	0.001	0.999	0.000
M51.4 Schmorl's nodes	0.001	0.999	0.000
J04 Acute laryngitis and tracheitis	0.001	0.999	0.000
E87.4 Mixed disorder of acid-base balance	0.001	0.999	0.000
J05.1 Acute epiglottitis	0.001	0.999	0.000
K62.6 Ulcer of anus and rectum	0.000	0.999	0.001
Z57.5 Occupational exposure to toxic agents in other industries	0.001	0.999	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.000	0.999	0.001
E87.2 Acidosis	0.001	0.999	0.000
M51.2 Other specified intervertebral disk displacement	0.001	0.999	0.000
W50.9 Unspecified place	0.001	0.999	0.000
B37.7 Candidal septicaemia	0.001	0.999	0.000
B37.6 Candidal endocarditis	0.001	0.999	0.000
B37.5 Candidal meningitis	0.001	0.999	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.999	0.001
Z60.2 Living alone	0.001	0.999	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.999	0.001
J04.2 Acute laryngotracheitis	0.001	0.999	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.001	0.999	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.001	0.999	0.000
H93.1 Tinnitus	0.000	0.999	0.001
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.999	0.001
M87.2 Osteonecrosis due to previous trauma	0.001	0.999	0.000
V23.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.999	0.001
V23.5 Passenger injured in traffic accident	0.000	0.999	0.001
V23.3 Person injured while boarding or alighting	0.000	0.999	0.001
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.999	0.001
V23.1 Passenger injured in nontraffic accident	0.000	0.999	0.001
V23.0 Driver injured in nontraffic accident	0.000	0.999	0.001
Z50.5 Speech therapy	0.000	0.999	0.001
D30.3 Bladder	0.000	0.999	0.001
G83.4 Cauda equina syndrome	0.000	0.999	0.001
K42.0 Umbilical hernia with obstruction, without gangrene	0.001	0.999	0.000
N13.8 Other obstructive and reflux uropathy	0.001	0.999	0.000
R25.2 Cramp and spasm	0.000	0.999	0.001
Z57.2 Occupational exposure to dust	0.001	0.999	0.000
I72.8 Aneurysm of other specified arteries	0.001	0.999	0.000
Z36.8 Other antenatal screening	0.001	0.999	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.001	0.999	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.001	0.999	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.001	0.999	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.001	0.999	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations