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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2452591
log Bayes Factor = <0.0001
Chromosome 4   position 95,476,719  (GRCh37) Explore rs2452591 on Ensembl!
Variant rs2452591 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C61 Malignant neoplasm of prostate
0.000 0.944 0.056
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.952 0.048
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.954 0.046
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.954 0.046
O63.0 Prolonged first stage (of labour)
0.000 0.955 0.045
T39.0 Salicylates
0.000 0.956 0.044
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.956 0.044
T46 Poisoning by agents primarily affecting the cardiovascular system
0.000 0.957 0.043
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.957 0.043
D06.9 Cervix, unspecified
0.000 0.958 0.042
T36 Poisoning by systemic antibiotics
0.000 0.958 0.042
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.000 0.958 0.042
O63.9 Long labour, unspecified
0.000 0.958 0.042
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.000 0.958 0.042
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.960 0.040
O63 Long labour
0.000 0.960 0.040
T36.0 Penicillins
0.000 0.961 0.039
T46.4 Angiotensin-converting-enzyme inhibitors
0.000 0.962 0.038
T46.1 Calcium-channel blockers
0.000 0.962 0.038
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.963 0.037
T45.0 Antiallergic and antiemetic drugs
0.000 0.963 0.037
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.000 0.963 0.037
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.000 0.963 0.036
T45.5 Anticoagulants
0.000 0.964 0.036
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.964 0.036
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.964 0.036
T43.0 Tricyclic and tetracyclic antidepressants
0.000 0.964 0.036
T50.4 Drugs affecting uric acid metabolism
0.000 0.964 0.035
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.000 0.965 0.035
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.965 0.035
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.965 0.035
T43.6 Psychostimulants with abuse potential
0.000 0.966 0.034
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.966 0.034
T39.4 Antirheumatics, not elsewhere classified
0.000 0.967 0.033
T39.2 Pyrazolone derivatives
0.000 0.967 0.033
T50.7 Analeptics and opioid receptor antagonists
0.000 0.967 0.033
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.967 0.033
T50.5 Appetite depressants
0.000 0.967 0.033
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.967 0.033
T50.1 Loop [high-ceiling] diuretics
0.000 0.967 0.033
T50.0 Mineralocorticoids and their antagonists
0.000 0.967 0.033
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.968 0.032
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.968 0.032
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.000 0.968 0.032
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.000 0.968 0.032
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.000 0.968 0.032
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.000 0.968 0.032
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.000 0.968 0.032
T44.1 Other parasympathomimetics [cholinergics]
0.000 0.968 0.032
T44.0 Anticholinesterase agents
0.000 0.968 0.032
T43.4 Butyrophenone and thioxanthene neuroleptics
0.000 0.968 0.032
T50.8 Diagnostic agents
0.000 0.968 0.032
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.000 0.968 0.032
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.000 0.969 0.031
T46.8 Antivaricose drugs, including sclerosing agents
0.000 0.969 0.031
T46.7 Peripheral vasodilators
0.000 0.969 0.031
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.000 0.969 0.030
T43.2 Other and unspecified antidepressants
0.000 0.969 0.031
T36.9 Systemic antibiotic, unspecified
0.000 0.970 0.030
T36.8 Other systemic antibiotics
0.000 0.970 0.030
T36.7 Antifungal antibiotics, systemically used
0.000 0.970 0.030
T36.6 Rifamycins
0.000 0.970 0.030
T36.5 Aminoglycosides
0.000 0.970 0.030
T36.3 Macrolides
0.000 0.970 0.030
T36.2 Chloramphenicol group
0.000 0.970 0.030
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.000 0.970 0.030
T45.9 Primarily systemic and haematological agent, unspecified
0.000 0.970 0.030
T45.8 Other primarily systemic and haematological agents
0.000 0.970 0.030
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.000 0.970 0.030
T45.6 Fibrinolysis-affecting drugs
0.000 0.970 0.030
T45.4 Iron and its compounds
0.000 0.970 0.030
T45.3 Enzymes, not elsewhere classified
0.000 0.970 0.030
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.000 0.970 0.030
T43.9 Psychotropic drug, unspecified
0.000 0.970 0.030
T43.8 Other psychotropic drugs, not elsewhere classified
0.000 0.970 0.030
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.000 0.970 0.030
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.970 0.030
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.000 0.971 0.029
O63.2 Delayed delivery of second twin, triplet, etc.
0.000 0.971 0.029
T39.1 4-Aminophenol derivatives
0.000 0.972 0.028
T36.4 Tetracyclines
0.000 0.972 0.028
T43.3 Phenothiazine antipsychotics and neuroleptics
0.000 0.973 0.027
T45.2 Vitamins, not elsewhere classified
0.000 0.973 0.026
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.974 0.026
T38.1 Thyroid hormones and substitutes
0.000 0.974 0.026
T46.5 Other antihypertensive drugs, not elsewhere classified
0.000 0.974 0.026
T38.8 Other and unspecified hormones and their synthetic substitutes
0.000 0.974 0.026
T38.9 Other and unspecified hormone antagonists
0.000 0.974 0.026
T38.7 Androgens and anabolic congeners
0.000 0.974 0.026
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.000 0.974 0.026
T38.5 Other oestrogens and progestogens
0.000 0.974 0.026
T38.4 Oral contraceptives
0.000 0.974 0.026
T38.2 Antithyroid drugs
0.000 0.974 0.026
T43.5 Other and unspecified antipsychotics and neuroleptics
0.000 0.974 0.026
T45.1 Antineoplastic and immunosuppressive drugs
0.000 0.975 0.025
T48.6 Antiasthmatics, not elsewhere classified
0.000 0.975 0.025
T41.5 Therapeutic gases
0.000 0.975 0.025
T41.4 Anaesthetic, unspecified
0.000 0.975 0.025
T41.3 Local anaesthetics
0.000 0.975 0.025
T41.2 Other and unspecified general anaesthetics
0.000 0.975 0.025
T41.1 Intravenous anaesthetics
0.000 0.975 0.025
T41.0 Inhaled anaesthetics
0.000 0.975 0.025
T49.9 Topical agent, unspecified
0.000 0.975 0.025
T49.8 Other topical agents
0.000 0.975 0.025
T49.7 Dental drugs, topically applied
0.000 0.975 0.025
T49.6 Otorhinolaryngological drugs and preparations
0.000 0.975 0.025
T49.5 Ophthalmological drugs and preparations
0.000 0.975 0.025
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.000 0.975 0.025
T49.3 Emollients, demulcents and protectants
0.000 0.975 0.025
T49.2 Local astringents and local detergents
0.000 0.975 0.025
T49.1 Antipruritics
0.000 0.975 0.025
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.000 0.975 0.025
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.000 0.975 0.024
T48.4 Expectorants
0.000 0.975 0.024
T48.3 Antitussives
0.000 0.975 0.024
T48.2 Other and unspecified agents primarily acting on muscles
0.000 0.975 0.024
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.000 0.975 0.024
T48.0 Oxytocic drugs
0.000 0.975 0.024
T46.3 Coronary vasodilators, not elsewhere classified
0.000 0.976 0.024
T38.0 Glucocorticoids and synthetic analogues
0.000 0.976 0.024
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.000 0.977 0.023
T37.5 Antiviral drugs
0.000 0.977 0.023
T37.4 Anthelminthics
0.000 0.977 0.023
T37.3 Other antiprotozoal drugs
0.000 0.977 0.023
T37.2 Antimalarials and drugs acting on other blood protozoa
0.000 0.977 0.023
T37.1 Antimycobacterial drugs
0.000 0.977 0.023
T37.0 Sulphonamides
0.000 0.977 0.023
T48.5 Anti-common-cold drugs
0.000 0.977 0.023
T40.6 Other and unspecified narcotics
0.000 0.978 0.022
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.000 0.978 0.022
T47.8 Other agents primarily affecting the gastro-intestinal system
0.000 0.978 0.022
T47.7 Emetics
0.000 0.978 0.022
T47.6 Antidiarrhoeal drugs
0.000 0.978 0.022
T47.5 Digestants
0.000 0.978 0.022
T47.3 Saline and osmotic laxatives
0.000 0.978 0.022
T47.2 Stimulant laxatives
0.000 0.978 0.022
T47.0 Histamine H(2)-receptor antagonists
0.000 0.978 0.022
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.978 0.022
T37.8 Other specified systemic anti-infectives and antiparasitics
0.000 0.979 0.021
T47.4 Other laxatives
0.000 0.980 0.020
T40.5 Cocaine
0.000 0.980 0.019
T47.1 Other antacids and anti-gastric-secretion drugs
0.000 0.980 0.019
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.000 0.981 0.019
T40.8 Lysergide [LSD]
0.000 0.981 0.019
T40.7 Cannabis (derivatives)
0.000 0.981 0.019
T40.3 Methadone
0.000 0.981 0.019
T40.1 Heroin
0.000 0.981 0.019
T40.0 Opium
0.000 0.981 0.019
Z85.4 Personal history of malignant neoplasm of genital organs
0.000 0.981 0.019
T40.4 Other synthetic narcotics
0.000 0.981 0.019
O63.1 Prolonged second stage (of labour)
0.000 0.982 0.018
D06 Carcinoma in situ of cervix uteri
0.000 0.982 0.018
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.982 0.018
T42.1 Iminostilbenes
0.000 0.984 0.016
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.984 0.016
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.984 0.016
T42.2 Succinimides and oxazolidinediones
0.000 0.984 0.016
T42.0 Hydantoin derivatives
0.000 0.984 0.015
C60-C63 Malignant neoplasms of male genital organs
0.000 0.985 0.015
T42.3 Barbiturates
0.000 0.985 0.014
D06.0 Endocervix
0.000 0.987 0.013
D06.7 Other parts of cervix
0.000 0.987 0.013
D06.1 Exocervix
0.000 0.987 0.013
C50.3 Lower-inner quadrant of breast
0.012 0.988 0.000
T42.4 Benzodiazepines
0.000 0.988 0.012
C62 Malignant neoplasm of testis
0.000 0.990 0.010
C60 Malignant neoplasm of penis
0.000 0.990 0.010
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.000 0.990 0.010
C63 Malignant neoplasm of other and unspecified male genital organs
0.000 0.990 0.010
H52.0 Hypermetropia
0.009 0.991 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.000 0.991 0.009
N60.3 Fibrosclerosis of breast
0.009 0.991 0.000
C62.9 Testis, unspecified
0.000 0.992 0.008
C62.0 Undescended testis
0.000 0.992 0.008
O72 Postpartum haemorrhage
0.000 0.992 0.008
C60.1 Glans penis
0.000 0.992 0.007
C60.8 Overlapping lesion of penis
0.000 0.992 0.007
C60.2 Body of penis
0.000 0.992 0.007
C63.9 Male genital organ, unspecified
0.000 0.993 0.007
C63.8 Overlapping lesion of male genital organs
0.000 0.993 0.007
C63.7 Other specified male genital organs
0.000 0.993 0.007
C63.1 Spermatic cord
0.000 0.993 0.007
C63.0 Epididymis
0.000 0.993 0.007
O75 Other complications of labour and delivery, not elsewhere classified
0.000 0.993 0.007
O75.8 Other specified complications of labour and delivery
0.000 0.993 0.007
C60.9 Penis, unspecified
0.000 0.993 0.007
C60.0 Prepuce
0.000 0.993 0.007
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.993 0.007
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.000 0.993 0.007
O75.7 Vaginal delivery following previous Caesarean section
0.000 0.993 0.007
D51 Vitamin B12 deficiency anaemia
0.000 0.993 0.007
O60-O75 Complications of labour and delivery
0.000 0.993 0.007
O72.0 Third-stage haemorrhage
0.000 0.994 0.006
C63.2 Scrotum
0.000 0.994 0.006
S91.3 Open wound of other parts of foot
0.006 0.994 0.000
C62.1 Descended testis
0.000 0.994 0.006
Z48.0 Attention to surgical dressings and sutures
0.000 0.994 0.006
O75.2 Pyrexia during labour, not elsewhere classified
0.000 0.994 0.006
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.994 0.006
O72.3 Postpartum coagulation defects
0.000 0.994 0.006
O75.9 Complication of labour and delivery, unspecified
0.000 0.994 0.005
O75.5 Delayed delivery after artificial rupture of membranes
0.000 0.994 0.005
O75.4 Other complications of obstetric surgery and procedures
0.000 0.994 0.005
O75.3 Other infection during labour
0.000 0.994 0.005
O75.1 Shock during or following labour and delivery
0.000 0.994 0.005
O72.1 Other immediate postpartum haemorrhage
0.000 0.994 0.006
M34.9 Systemic sclerosis, unspecified
0.005 0.995 0.000
O74 Complications of anaesthesia during labour and delivery
0.000 0.995 0.005
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.000 0.995 0.005
D51.2 Transcobalamin II deficiency
0.000 0.995 0.005
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.000 0.995 0.005
O60 Preterm delivery
0.000 0.995 0.005
D72.8 Other specified disorders of white blood cells
0.005 0.995 0.000
O61 Failed induction of labour
0.000 0.995 0.005
S80.9 Superficial injury of lower leg, unspecified
0.005 0.995 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.995 0.004
O64 Obstructed labour due to malposition and malpresentation of foetus
0.000 0.995 0.005
M34.1 CR(E)ST syndrome
0.005 0.995 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.000 0.995 0.004
S80.8 Other superficial injuries of lower leg
0.004 0.996 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.000 0.996 0.004
M34 Systemic sclerosis
0.004 0.996 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.000 0.996 0.004
I99 Other and unspecified disorders of circulatory system
0.004 0.996 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.000 0.996 0.004
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery
0.000 0.996 0.004
O42 Premature rupture of membranes
0.000 0.996 0.004
O62 Abnormalities of forces of labour
0.000 0.996 0.004
S72.30 Fracture of shaft of femur (closed)
0.004 0.996 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.000 0.996 0.004
O64.1 Obstructed labour due to breech presentation
0.000 0.996 0.004
O71 Other obstetric trauma
0.000 0.996 0.004
O75.0 Maternal distress during labour and delivery
0.000 0.996 0.004
O61.1 Failed instrumental induction of labour
0.000 0.996 0.004
O74.9 Complication of anaesthesia during labour and delivery, unspecified
0.000 0.996 0.004
O74.8 Other complications of anaesthesia during labour and delivery
0.000 0.996 0.004
O74.7 Failed or difficult intubation during labour and delivery
0.000 0.996 0.004
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery
0.000 0.996 0.004
O74.4 Toxic reaction to local anaesthesia during labour and delivery
0.000 0.996 0.004
O74.3 Central nervous system complications of anaesthesia during labour and delivery
0.000 0.996 0.004
O74.2 Cardiac complications of anaesthesia during labour and delivery
0.000 0.996 0.004
O74.1 Other pulmonary complications of anaesthesia during labour and delivery
0.000 0.996 0.004
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery
0.000 0.996 0.004
H61.0 Perichondritis of external ear
0.000 0.996 0.004
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.000 0.996 0.004
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.000 0.996 0.004
O71.4 Obstetric high vaginal laceration alone
0.000 0.996 0.004
O60.3 Preterm delivery without spontaneous labour
0.000 0.996 0.004
O60.2 Preterm spontaneous labour with term delivery
0.000 0.996 0.004
O60.1 Preterm spontaneous labour with preterm delivery
0.000 0.996 0.004
O60.0 Preterm labour without delivery
0.000 0.996 0.004
O69 Labour and delivery complicated by umbilical cord complications
0.000 0.996 0.004
O66 Other obstructed labour
0.000 0.996 0.004
R32 Unspecified urinary incontinence
0.000 0.996 0.004
O62.1 Secondary uterine inertia
0.000 0.996 0.004
O61.9 Failed induction of labour, unspecified
0.000 0.996 0.004
M34.0 Progressive systemic sclerosis
0.004 0.996 0.000
M34.8 Other forms of systemic sclerosis
0.004 0.996 0.000
O61.8 Other failed induction of labour
0.000 0.996 0.004
O42.2 Premature rupture of membranes, labour delayed by therapy
0.000 0.996 0.004
O64.2 Obstructed labour due to face presentation
0.000 0.996 0.004
S80 Superficial injury of lower leg
0.004 0.996 0.000
S62.50 Fracture of thumb (closed)
0.000 0.996 0.004
O64.5 Obstructed labour due to compound presentation
0.000 0.996 0.003
O64.4 Obstructed labour due to shoulder presentation
0.000 0.996 0.003
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.000 0.997 0.003
M34.2 Systemic sclerosis induced by drugs and chemicals
0.003 0.997 0.000
O62.9 Abnormality of forces of labour, unspecified
0.000 0.997 0.003
O42.9 Premature rupture of membranes, unspecified
0.000 0.997 0.003
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified
0.000 0.997 0.003
O65.8 Obstructed labour due to other maternal pelvic abnormalities
0.000 0.997 0.003
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction
0.000 0.997 0.003
O65.2 Obstructed labour due to pelvic inlet contraction
0.000 0.997 0.003
O65.1 Obstructed labour due to generally contracted pelvis
0.000 0.997 0.003
O65.0 Obstructed labour due to deformed pelvis
0.000 0.997 0.003
O71.5 Other obstetric injury to pelvic organs
0.000 0.997 0.003
O73 Retained placenta and membranes, without haemorrhage
0.000 0.997 0.003
K56.2 Volvulus
0.003 0.997 0.000
O64.3 Obstructed labour due to brow presentation
0.000 0.997 0.003
O62.8 Other abnormalities of forces of labour
0.000 0.997 0.003
N30.1 Interstitial cystitis (chronic)
0.003 0.997 0.000
Z52.4 Kidney donor
0.000 0.997 0.003
O71.6 Obstetric damage to pelvic joints and ligaments
0.000 0.997 0.003
O71.2 Postpartum inversion of uterus
0.000 0.997 0.003
O71.1 Rupture of uterus during labour
0.000 0.997 0.003
O71.0 Rupture of uterus before onset of labour
0.000 0.997 0.003
O66.0 Obstructed labour due to shoulder dystocia
0.000 0.997 0.003
S80.7 Multiple superficial injuries of lower leg
0.003 0.997 0.000
O71.3 Obstetric laceration of cervix
0.000 0.997 0.003
I71.3 Abdominal aortic aneurysm, ruptured
0.003 0.997 0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified
0.000 0.997 0.003
O67.0 Intrapartum haemorrhage with coagulation defect
0.000 0.997 0.003
O62.0 Primary inadequate contractions
0.000 0.997 0.003
T40.2 Other opioids
0.000 0.997 0.003
O65.5 Obstructed labour due to abnormality of maternal pelvic organs
0.000 0.997 0.003
S72.3 Fracture of shaft of femur
0.003 0.997 0.000
Z52.8 Donor of other organs and tissues
0.000 0.997 0.003
N80.0 Endometriosis of uterus
0.003 0.997 0.000
O69.8 Labour and delivery complicated by other cord complications
0.000 0.997 0.003
O69.5 Labour and delivery complicated by vascular lesion of cord
0.000 0.997 0.003
O69.4 Labour and delivery complicated by vasa praevia
0.000 0.997 0.003
O69.3 Labour and delivery complicated by short cord
0.000 0.997 0.003
O66.8 Other specified obstructed labour
0.000 0.997 0.003
O66.3 Obstructed labour due to other abnormalities of foetus
0.000 0.997 0.003
O66.1 Obstructed labour due to locked twins
0.000 0.997 0.003
O61.0 Failed medical induction of labour
0.000 0.997 0.003
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.000 0.997 0.003
O71.9 Obstetric trauma, unspecified
0.000 0.997 0.003
S80.0 Contusion of knee
0.003 0.997 0.000
O67.8 Other intrapartum haemorrhage
0.000 0.997 0.003
C67.2 Lateral wall of bladder
0.000 0.997 0.003
O64.8 Obstructed labour due to other malposition and malpresentation
0.000 0.997 0.002
O66.2 Obstructed labour due to unusually large foetus
0.000 0.997 0.003
O71.7 Obstetric haematoma of pelvis
0.000 0.997 0.002
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.003 0.997 0.000
O66.9 Obstructed labour, unspecified
0.000 0.997 0.002
M77.12 Lateral epicondylitis (Upper arm)
0.003 0.997 0.000
Z52 Donors of organs and tissues
0.000 0.997 0.003
O66.4 Failed trial of labour, unspecified
0.000 0.997 0.002
O69.0 Labour and delivery complicated by prolapse of cord
0.000 0.997 0.002
I08.8 Other multiple valve diseases
0.003 0.997 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.000 0.997 0.003
R60.0 Localised oedema
0.000 0.997 0.003
S91 Open wound of ankle and foot
0.003 0.997 0.000
O71.8 Other specified obstetric trauma
0.000 0.997 0.002
S72.31 Fracture of shaft of femur (open)
0.002 0.998 0.000
O62.2 Other uterine inertia
0.002 0.998 0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified
0.000 0.998 0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.002 0.998 0.000
O67.9 Intrapartum haemorrhage, unspecified
0.000 0.998 0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)
0.000 0.998 0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)
0.000 0.998 0.002
S32.00 Fracture of lumbar vertebra (closed)
0.000 0.998 0.002
S91.1 Open wound of toe(s) without damage to nail
0.002 0.998 0.000
Z52.2 Bone donor
0.000 0.998 0.002
H40.5 Glaucoma secondary to other eye disorders
0.002 0.998 0.000
R60.9 Oedema, unspecified
0.000 0.998 0.002
D72 Other disorders of white blood cells
0.002 0.998 0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage
0.000 0.998 0.002
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.000 0.998 0.002
S72.90 Fracture of femur, part unspecified (closed)
0.002 0.998 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.002 0.998 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.002 0.998 0.000
X78.0 Home
0.000 0.998 0.002
I71 Aortic aneurysm and dissection
0.002 0.998 0.000
O62.3 Precipitate labour
0.001 0.998 0.002
Z52.9 Donor of unspecified organ or tissue
0.000 0.998 0.002
Z52.7 Heart donor
0.000 0.998 0.002
Z52.6 Liver donor
0.000 0.998 0.002
Z52.5 Cornea donor
0.000 0.998 0.002
Z52.1 Skin donor
0.000 0.998 0.002
S72.9 Fracture of femur, part unspecified
0.002 0.998 0.000
Z52.0 Blood donor
0.000 0.998 0.002
J46 Status asthmaticus
0.000 0.998 0.002
S91.7 Multiple open wounds of ankle and foot
0.002 0.998 0.000
Z52.3 Bone marrow donor
0.000 0.998 0.002
R60 Oedema, not elsewhere classified
0.000 0.998 0.002
S72 Fracture of femur
0.002 0.998 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.002 0.998 0.000
R60.1 Generalised oedema
0.000 0.998 0.002
C67.6 Ureteric orifice
0.000 0.998 0.002
G71.0 Muscular dystrophy
0.000 0.998 0.002
R06.1 Stridor
0.002 0.998 0.000
S72.8 Fractures of other parts of femur
0.002 0.998 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.000 0.998 0.002
S72.80 Fractures of other parts of femur (closed)
0.002 0.998 0.000
D72.9 Disorder of white blood cells, unspecified
0.002 0.998 0.000
D72.0 Genetic anomalies of leukocytes
0.002 0.998 0.000
S72.0 Fracture of neck of femur
0.002 0.998 0.000
S91.2 Open wound of toe(s) with damage to nail
0.002 0.998 0.000
D72.1 Eosinophilia
0.002 0.998 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.998 0.002
I71.1 Thoracic aortic aneurysm, ruptured
0.002 0.998 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.002 0.998 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.002 0.998 0.000
S32.40 Fracture of acetabulum (closed)
0.000 0.998 0.002
S72.00 Fracture of neck of femur (closed)
0.002 0.998 0.000
S72.91 Fracture of femur, part unspecified (open)
0.002 0.998 0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified
0.000 0.998 0.002
K05.3 Chronic periodontitis
0.000 0.998 0.002
S62.5 Fracture of thumb
0.000 0.998 0.002
C67 Malignant neoplasm of bladder
0.000 0.998 0.002
I71.0 Dissection of aorta [any part]
0.002 0.998 0.000
S72.7 Multiple fractures of femur
0.002 0.998 0.000
Z48 Other surgical follow-up care
0.000 0.998 0.002
T20.1 Burn of first degree of head and neck
0.002 0.998 0.000
H57.1 Ocular pain
0.002 0.998 0.000
S72.81 Fractures of other parts of femur (open)
0.002 0.998 0.000
O73.0 Retained placenta, without haemorrhage
0.000 0.998 0.002
H52.4 Presbyopia
0.002 0.998 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.002 0.998 0.000
M25.86 Other specified joint disorders (Lower leg)
0.000 0.998 0.002
S72.01 Fracture of neck of femur (open)
0.002 0.998 0.000
G71.3 Mitochondrial myopathy, not elsewhere classified
0.000 0.998 0.002
S72.2 Subtrochanteric fracture
0.002 0.998 0.000
S91.0 Open wound of ankle
0.001 0.998 0.000
H52 Disorders of refraction and accommodation
0.002 0.998 0.000
H52.2 Astigmatism
0.002 0.998 0.000
M79.60 Pain in limb (Multiple sites)
0.002 0.998 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.001 0.998 0.001
S42.30 Fracture of shaft of humerus (closed)
0.002 0.998 0.000
C67.1 Dome of bladder
0.000 0.998 0.002
G71 Primary disorders of muscles
0.000 0.998 0.002
S72.71 Multiple fractures of femur (open)
0.001 0.998 0.000
S72.70 Multiple fractures of femur (closed)
0.001 0.998 0.000
C67.7 Urachus
0.000 0.998 0.001
S39.8 Other specified injuries of abdomen, lower back and pelvis
0.000 0.998 0.001
T51.0 Ethanol
0.000 0.998 0.002
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.000 0.998 0.002
H58.8 Visual disturbances in diseases classified elsewhere
0.000 0.998 0.001
K38.1 Appendicular concretions
0.000 0.998 0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)
0.001 0.998 0.000
C67.0 Trigone of bladder
0.000 0.998 0.001
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.998 0.001
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.002 0.998 0.000
H02.5 Other disorders affecting eyelid function
0.002 0.998 0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis
0.002 0.998 0.000
S32.0 Fracture of lumbar vertebra
0.000 0.998 0.001
C67.9 Bladder, unspecified
0.000 0.998 0.002
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.001 0.998 0.000
O69.2 Labour and delivery complicated by other cord entanglement
0.000 0.998 0.001
S72.1 Pertrochanteric fracture
0.001 0.998 0.000
S72.21 Subtrochanteric fracture (open)
0.001 0.999 0.000
H52.6 Other disorders of refraction
0.001 0.999 0.000
H52.5 Disorders of accommodation
0.001 0.999 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.001 0.999 0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.001 0.999 0.000
M77.1 Lateral epicondylitis
0.001 0.999 0.000
H57 Other disorders of eye and adnexa
0.001 0.999 0.000
I05.9 Mitral valve disease, unspecified
0.000 0.999 0.001
T20.0 Burn of unspecified degree of head and neck
0.001 0.999 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.001 0.999 0.000
C67.8 Overlapping lesion of bladder
0.000 0.999 0.001
G71.9 Primary disorder of muscle, unspecified
0.000 0.999 0.001
G71.8 Other primary disorders of muscles
0.000 0.999 0.001
G71.2 Congenital myopathies
0.000 0.999 0.001
S39.7 Other multiple injuries of abdomen, lower back and pelvis
0.000 0.999 0.001
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)
0.000 0.999 0.001
M40.24 Other and unspecified kyphosis (Thoracic region)
0.001 0.999 0.000
I33.0 Acute and subacute infective endocarditis
0.001 0.999 0.000
I84.3 External thrombosed haemorrhoids
0.001 0.999 0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)
0.000 0.999 0.001
S62.51 Fracture of thumb (open)
0.000 0.999 0.001
C67.4 Posterior wall of bladder
0.000 0.999 0.001
C67.3 Anterior wall of bladder
0.000 0.999 0.001
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.001 0.999 0.000
O86.0 Infection of obstetric surgical wound
0.000 0.999 0.001
W29.9 Unspecified place
0.001 0.999 0.000
Z85.6 Personal history of leukaemia
0.000 0.999 0.001
S32.01 Fracture of lumbar vertebra (open)
0.000 0.999 0.001
S72.11 Pertrochanteric fracture (open)
0.001 0.999 0.000
G71.1 Myotonic disorders
0.000 0.999 0.001
Q05.9 Spina bifida, unspecified
0.000 0.999 0.001
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis
0.000 0.999 0.001
Z01.5 Diagnostic skin and sensitisation tests
0.001 0.999 0.000
M77.19 Lateral epicondylitis (Site unspecified)
0.001 0.999 0.000
M77.18 Lateral epicondylitis-Other
0.001 0.999 0.000
M77.17 Lateral epicondylitis-Ankle/Foot
0.001 0.999 0.000
M77.16 Lateral epicondylitis (Lower leg)
0.001 0.999 0.000
M77.15 Lateral epicondylitis (Pelvic region and thigh)
0.001 0.999 0.000
M77.14 Lateral epicondylitis-Hand
0.001 0.999 0.000
M77.11 Lateral epicondylitis-Shldr region
0.001 0.999 0.000
M77.10 Lateral epicondylitis (Multiple sites)
0.001 0.999 0.000
S62.60 Fracture of other finger (closed)
0.000 0.999 0.001
M40.26 Other and unspecified kyphosis (Lumbar region)
0.001 0.999 0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)
0.001 0.999 0.000
Z48.8 Other specified surgical follow-up care
0.000 0.999 0.001
S72.20 Subtrochanteric fracture (closed)
0.001 0.999 0.000
C67.5 Bladder neck
0.000 0.999 0.001
S40.8 Other superficial injuries of shoulder and upper arm
0.001 0.999 0.000
G00.1 Pneumococcal meningitis
0.000 0.999 0.001
H52.7 Disorder of refraction, unspecified
0.001 0.999 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.000 0.999 0.001
T24.2 Burn of second degree of hip and lower limb, except ankle and foot
0.000 0.999 0.001
S02.60 Fracture of mandible (closed)
0.000 0.999 0.001
M80.9 Unspecified osteoporosis with pathological fracture
0.000 0.999 0.001
S32.4 Fracture of acetabulum
0.000 0.999 0.001
T20.2 Burn of second degree of head and neck
0.001 0.999 0.000
T20 Burn and corrosion of head and neck
0.001 0.999 0.000
M40.25 Other and unspecified kyphosis (Thoracolumbar region)
0.001 0.999 0.000
M43.02 Spondylolysis (Cervical region)
0.001 0.999 0.000
M77.13 Lateral epicondylitis-Forearm
0.001 0.999 0.000
M77.94 Enthesopathy, unspecified (Hand)
0.001 0.999 0.000
H31.8 Other specified disorders of choroid
0.001 0.999 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.001 0.999 0.000
S49.8 Other specified injuries of shoulder and upper arm
0.001 0.999 0.000
S72.4 Fracture of lower end of femur
0.001 0.999 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.000 0.999 0.001
M24.23 Disorder of ligament (Forearm)
0.001 0.999 0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)
0.001 0.999 0.000
C02.1 Border of tongue
0.001 0.999 0.000
T92.0 Sequelae of open wound of upper limb
0.000 0.999 0.001
X78 Intentional self-harm by sharp object
0.000 0.999 0.001
G90.9 Disorder of autonomic nervous system, unspecified
0.000 0.999 0.001
H57.8 Other specified disorders of eye and adnexa
0.001 0.999 0.000
I74.5 Embolism and thrombosis of iliac artery
0.001 0.999 0.000
N18.4 Chronic kidney disease, stage 4
0.001 0.999 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.001 0.999 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.000 0.999 0.001
M40.2 Other and unspecified kyphosis
0.001 0.999 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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