TreeWAS – Variant ID: rs2483374

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D12.3 Transverse colon	0.000	0.882	0.118
M79.86 Other specified soft tissue disorders (Lower leg)	0.000	0.935	0.065
S93.0 Dislocation of ankle joint	0.038	0.962	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.035	0.965	0.000
S93.1 Dislocation of toe(s)	0.030	0.970	0.000
S90-S99 Injuries to the ankle and foot	0.029	0.971	0.000
S92 Fracture of foot, except ankle	0.028	0.972	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.028	0.972	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.028	0.972	0.000
S91 Open wound of ankle and foot	0.027	0.973	0.000
S93.4 Sprain and strain of ankle	0.025	0.974	0.000
S93.5 Sprain and strain of toe(s)	0.025	0.974	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.025	0.975	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.024	0.976	0.000
S92.0 Fracture of calcaneus	0.024	0.976	0.000
S92.3 Fracture of metatarsal bone	0.024	0.976	0.000
S91.2 Open wound of toe(s) with damage to nail	0.023	0.977	0.000
S91.3 Open wound of other parts of foot	0.023	0.977	0.000
S91.1 Open wound of toe(s) without damage to nail	0.023	0.977	0.000
S92.4 Fracture of great toe	0.022	0.978	0.000
S92.5 Fracture of other toe	0.022	0.978	0.000
S92.2 Fracture of other tarsal bone(s)	0.022	0.978	0.000
S92.1 Fracture of talus	0.021	0.978	0.000
S98 Traumatic amputation of ankle and foot	0.021	0.979	0.000
S95 Injury of blood vessels at ankle and foot level	0.021	0.979	0.000
S94 Injury of nerves at ankle and foot level	0.021	0.979	0.000
S92.30 Fracture of metatarsal bone (closed)	0.021	0.979	0.000
S92.9 Fracture of foot, unspecified	0.020	0.980	0.000
S97 Crushing injury of ankle and foot	0.020	0.980	0.000
S92.00 Fracture of calcaneus (closed)	0.020	0.980	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.020	0.980	0.000
S92.01 Fracture of calcaneus (open)	0.020	0.980	0.000
S91.7 Multiple open wounds of ankle and foot	0.020	0.980	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.019	0.981	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.019	0.981	0.000
S92.50 Fracture of other toe (closed)	0.019	0.981	0.000
S92.40 Fracture of great toe (closed)	0.019	0.981	0.000
S93.40 Sprain of unspecified ligament of ankle	0.018	0.981	0.000
S92.7 Multiple fractures of foot	0.018	0.981	0.000
S91.0 Open wound of ankle	0.018	0.982	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.018	0.982	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.018	0.982	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.018	0.982	0.000
S92.31 Fracture of metatarsal bone (open)	0.017	0.983	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.017	0.983	0.000
Z95.0 Presence of cardiac pacemaker	0.017	0.983	0.000
S92.10 Fracture of talus (closed)	0.017	0.983	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.016	0.984	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.016	0.984	0.000
S92.11 Fracture of talus (open)	0.016	0.984	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.015	0.985	0.000
S94.8 Injury of other nerves at ankle and foot level	0.015	0.985	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.015	0.985	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.015	0.985	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.015	0.985	0.000
S94.1 Injury of medial plantar nerve	0.015	0.985	0.000
S94.0 Injury of lateral plantar nerve	0.015	0.985	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.015	0.985	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.015	0.985	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.015	0.985	0.000
S95.2 Injury of dorsal vein of foot	0.015	0.985	0.000
S95.1 Injury of plantar artery of foot	0.015	0.985	0.000
S95.0 Injury of dorsal artery of foot	0.015	0.985	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.015	0.985	0.000
S98.3 Traumatic amputation of other parts of foot	0.015	0.985	0.000
S98.2 Traumatic amputation of two or more toes	0.015	0.985	0.000
S98.1 Traumatic amputation of one toe	0.015	0.985	0.000
S98.0 Traumatic amputation of foot at ankle level	0.015	0.985	0.000
S92.91 Fracture of foot, unspecified (open)	0.015	0.985	0.000
S92.90 Fracture of foot, unspecified (closed)	0.015	0.985	0.000
S97.0 Crushing injury of ankle	0.015	0.985	0.000
S90 Superficial injury of ankle and foot	0.015	0.985	0.000
S92.41 Fracture of great toe (open)	0.014	0.985	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.014	0.986	0.000
S97.1 Crushing injury of toe(s)	0.014	0.986	0.000
S99 Other and unspecified injuries of ankle and foot	0.014	0.986	0.000
S92.71 Multiple fractures of foot (open)	0.013	0.986	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.013	0.987	0.000
S92.51 Fracture of other toe (open)	0.013	0.987	0.000
S90.3 Contusion of other and unspecified parts of foot	0.012	0.988	0.000
S92.70 Multiple fractures of foot (closed)	0.011	0.988	0.000
S90.0 Contusion of ankle	0.011	0.989	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.011	0.989	0.000
S90.2 Contusion of toe(s) with damage to nail	0.011	0.989	0.000
S90.1 Contusion of toe(s) without damage to nail	0.010	0.989	0.000
S99.7 Multiple injuries of ankle and foot	0.010	0.990	0.000
S90.8 Other superficial injuries of ankle and foot	0.009	0.990	0.000
S99.8 Other specified injuries of ankle and foot	0.009	0.991	0.000
J33.8 Other polyp of sinus	0.000	0.992	0.008
K65.0 Acute peritonitis	0.000	0.993	0.007
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.993	0.007
S99.9 Unspecified injury of ankle and foot	0.006	0.994	0.000
E87.2 Acidosis	0.006	0.994	0.000
E10.3 With ophthalmic complications	0.000	0.994	0.006
S83.2 Tear of meniscus, current	0.000	0.994	0.006
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.995	0.001
M70.46 Prepatellar bursitis-Lower Leg	0.004	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.004	0.996	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.004	0.996	0.000
E06.9 Thyroiditis, unspecified	0.004	0.996	0.000
E06.3 Autoimmune thyroiditis	0.004	0.996	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.996	0.004
R41.3 Other amnesia	0.004	0.996	0.000
E16.2 Hypoglycaemia, unspecified	0.000	0.996	0.004
F52.2 Failure of genital response	0.004	0.996	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.000	0.996	0.004
S82.30 Fracture of lower end of tibia (closed)	0.004	0.996	0.000
S31.4 Open wound of vagina and vulva	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.000	0.996	0.004
S32.00 Fracture of lumbar vertebra (closed)	0.004	0.996	0.000
S31 Open wound of abdomen, lower back and pelvis	0.004	0.996	0.000
D26.1 Corpus uteri	0.000	0.996	0.004
E06 Thyroiditis	0.004	0.996	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.003	0.996	0.000
M89.98 Disorder of bone, unspecified (Other)	0.000	0.997	0.003
M89.96 Disorder of bone, unspecified (Lower leg)	0.000	0.997	0.003
S31.0 Open wound of lower back and pelvis	0.003	0.997	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.997	0.003
Z22.5 Carrier of viral hepatitis	0.000	0.997	0.003
G96.1 Disorders of meninges, not elsewhere classified	0.003	0.997	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M79.8 Other specified soft tissue disorders	0.000	0.997	0.003
M89.91 Disorder of bone, unspecified (Shoulder region)	0.000	0.997	0.003
M19.04 Primary arthrosis of other joints (Hand)	0.003	0.997	0.000
K65 Peritonitis	0.000	0.997	0.003
S31.3 Open wound of scrotum and testes	0.003	0.997	0.000
S31.2 Open wound of penis	0.003	0.997	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.003	0.997	0.000
G96 Other disorders of central nervous system	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.000	0.997	0.003
M89.92 Disorder of bone, unspecified (Upper arm)	0.000	0.997	0.003
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.000	0.997	0.003
M89.90 Disorder of bone, unspecified (Multiple sites)	0.000	0.997	0.003
N36.2 Urethral caruncle	0.000	0.997	0.003
S30 Superficial injury of abdomen, lower back and pelvis	0.003	0.997	0.000
S31.5 Open wound of other and unspecified external genital organs	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.003	0.997	0.000
E06.4 Drug-induced thyroiditis	0.003	0.997	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.003	0.997	0.000
E06.1 Subacute thyroiditis	0.003	0.997	0.000
E06.0 Acute thyroiditis	0.003	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.997	0.003
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.003	0.997	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.003	0.997	0.000
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
D35.1 Parathyroid gland	0.000	0.997	0.003
E06.5 Other chronic thyroiditis	0.003	0.997	0.000
F52.0 Lack or loss of sexual desire	0.003	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.997	0.003
M79.81 Other specified soft tissue disorders (Shoulder region)	0.000	0.997	0.003
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
O20.0 Threatened abortion	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.997	0.003
S37 Injury of urinary and pelvic organs	0.002	0.997	0.000
E29.1 Testicular hypofunction	0.000	0.997	0.003
S31.1 Open wound of abdominal wall	0.002	0.997	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.000	0.997	0.002
Z71.8 Other specified counselling	0.000	0.997	0.003
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.002
S33.1 Dislocation of lumbar vertebra	0.002	0.997	0.000
M79.88 Other specified soft tissue disorders (Other)	0.000	0.998	0.002
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.002	0.998	0.000
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
F52.7 Excessive sexual drive	0.002	0.998	0.000
F52.6 Nonorganic dyspareunia	0.002	0.998	0.000
F52.5 Nonorganic vaginismus	0.002	0.998	0.000
F52.4 Premature ejaculation	0.002	0.998	0.000
F52.3 Orgasmic dysfunction	0.002	0.998	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.002	0.998	0.000
R06.5 Mouth breathing	0.000	0.998	0.002
M54.22 Cervicalgia (Cervical region)	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.000	0.998	0.002
M79.82 Other specified soft tissue disorders (Upper arm)	0.000	0.998	0.002
J33 Nasal polyp	0.000	0.998	0.002
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
G96.8 Other specified disorders of central nervous system	0.002	0.998	0.000
M70.4 Prepatellar bursitis	0.002	0.998	0.000
S30.2 Contusion of external genital organs	0.002	0.998	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.000	0.998	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.998	0.002
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.998	0.002
E16.4 Abnormal secretion of gastrin	0.000	0.998	0.002
E16.3 Increased secretion of glucagon	0.000	0.998	0.002
S33.5 Sprain and strain of lumbar spine	0.002	0.998	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.002	0.998	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.998	0.002
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.002	0.998	0.000
S37.3 Injury of urethra	0.002	0.998	0.000
N87.0 Mild cervical dysplasia	0.002	0.998	0.000
S30.0 Contusion of lower back and pelvis	0.002	0.998	0.000
D32.9 Meninges, unspecified	0.000	0.998	0.002
H01.0 Blepharitis	0.000	0.998	0.002
S30.1 Contusion of abdominal wall	0.002	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.000	0.998	0.002
S32 Fracture of lumbar spine and pelvis	0.002	0.998	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.002	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.002	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.002	0.998	0.000
F50.2 Bulimia nervosa	0.002	0.998	0.000
S37.2 Injury of bladder	0.002	0.998	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.998	0.002
N87 Dysplasia of cervix uteri	0.002	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.002	0.998	0.000
E16.1 Other hypoglycaemia	0.000	0.998	0.002
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.000	0.998	0.002
S83.1 Dislocation of knee	0.000	0.998	0.002
S32.10 Fracture of sacrum (closed)	0.002	0.998	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.002	0.998	0.000
K65.8 Other peritonitis	0.000	0.998	0.002
D11.0 Parotid gland	0.002	0.998	0.000
S37.9 Injury of unspecified pelvic organ	0.002	0.998	0.000
S37.8 Injury of other pelvic organs	0.002	0.998	0.000
S37.7 Injury of multiple pelvic organs	0.002	0.998	0.000
S37.6 Injury of uterus	0.002	0.998	0.000
S37.5 Injury of Fallopian tube	0.002	0.998	0.000
S37.4 Injury of ovary	0.002	0.998	0.000
S37.1 Injury of ureter	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.000	0.998	0.002
S83.0 Dislocation of patella	0.000	0.998	0.002
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.002	0.998	0.000
S37.0 Injury of kidney	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.998	0.002
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.002	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.002	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.002	0.998	0.000
S34.3 Injury of cauda equina	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.002	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.002	0.998	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.998	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
R85.5 Abnormal microbiological findings	0.002	0.998	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.002	0.998	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.002	0.998	0.000
I74.5 Embolism and thrombosis of iliac artery	0.002	0.998	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.000	0.998	0.002
M70.49 Prepatellar bursitis-Site unspec	0.002	0.998	0.000
M70.48 Prepatellar bursitis-Other	0.002	0.998	0.000
M70.47 Prepatellar bursitis-Ankle/Foot	0.002	0.998	0.000
M70.45 Prepatellar bursitis-Pelvic/Thigh	0.002	0.998	0.000
M70.44 Prepatellar bursitis-Hand	0.002	0.998	0.000
M70.43 Prepatellar bursitis-Forearm	0.002	0.998	0.000
M70.42 Prepatellar bursitis-Upper arm	0.002	0.998	0.000
M70.41 Prepatellar bursitis-Shldr region	0.002	0.998	0.000
M70.40 Prepatellar bursitis-Mult sites	0.002	0.998	0.000
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.000	0.998	0.002
S82.3 Fracture of lower end of tibia	0.002	0.998	0.000
F51 Nonorganic sleep disorders	0.002	0.998	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.5 Injury of iliac blood vessels	0.002	0.998	0.000
S35.4 Injury of renal blood vessels	0.002	0.998	0.000
S35.3 Injury of portal or splenic vein	0.002	0.998	0.000
S35.2 Injury of coeliac or mesenteric artery	0.002	0.998	0.000
S35.1 Injury of inferior vena cava	0.002	0.998	0.000
S35.0 Injury of abdominal aorta	0.002	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.002	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.0 Crushing injury of external genital organs	0.002	0.998	0.000
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.998	0.002
Z71.5 Drug abuse counselling and surveillance	0.000	0.998	0.002
Z71.0 Person consulting on behalf of another person	0.000	0.998	0.002
S37.31 Injury of urethra (with open wound into cavity)	0.002	0.998	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.000	0.998	0.002
J33.1 Polypoid sinus degeneration	0.000	0.998	0.002
S32.2 Fracture of coccyx	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S36 Injury of intra-abdominal organs	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.002
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.002	0.998	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.002	0.998	0.000
F50 Eating disorders	0.002	0.998	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
T11.1 Open wound of upper limb, level unspecified	0.000	0.998	0.002
Z71.2 Person consulting for explanation of investigation findings	0.000	0.998	0.002
N87.1 Moderate cervical dysplasia	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.000	0.998	0.002
S32.11 Fracture of sacrum (open)	0.002	0.998	0.000
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
F51.5 Nightmares	0.002	0.998	0.000
F51.4 Sleep terrors [night terrors]	0.002	0.998	0.000
F51.3 Sleepwalking [somnambulism]	0.002	0.998	0.000
G03.9 Meningitis, unspecified	0.000	0.998	0.002
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
T11 Other injuries of upper limb, level unspecified	0.000	0.998	0.002
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.002	0.998	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.002	0.998	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.002	0.998	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.002	0.998	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.002	0.998	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.002	0.998	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.002	0.998	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.002	0.998	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.002	0.998	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.002	0.998	0.000
D12.9 Anus and anal canal	0.000	0.998	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.002	0.998	0.000
C09.9 Tonsil, unspecified	0.000	0.998	0.002
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
J01.9 Acute sinusitis, unspecified	0.002	0.998	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
E10.5 With peripheral circulatory complications	0.000	0.998	0.002
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.998	0.002
K08.2 Atrophy of edentulous alveolar ridge	0.002	0.998	0.000
Z71.6 Tobacco abuse counselling	0.000	0.998	0.002
Z92.0 Personal history of contraception	0.002	0.998	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.001	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.002	0.998	0.000
E05.8 Other thyrotoxicosis	0.002	0.998	0.000
F51.9 Nonorganic sleep disorder, unspecified	0.002	0.998	0.000
F51.8 Other nonorganic sleep disorders	0.002	0.998	0.000
F51.2 Nonorganic disorder of the sleep-wake schedule	0.002	0.998	0.000
F51.1 Nonorganic hypersomnia	0.002	0.998	0.000
F51.0 Nonorganic insomnia	0.002	0.998	0.000
Z90.0 Acquired absence of part of head and neck	0.000	0.998	0.002
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.002
Z71.9 Counselling, unspecified	0.000	0.998	0.002
S32.21 Fracture of coccyx (open)	0.001	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.001	0.998	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.001	0.998	0.000
S36.7 Injury of multiple intra-abdominal organs	0.001	0.998	0.000
S36.6 Injury of rectum	0.001	0.998	0.000
S36.5 Injury of colon	0.001	0.998	0.000
S36.3 Injury of stomach	0.001	0.998	0.000
S36.2 Injury of pancreas	0.001	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.001	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.001	0.998	0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.001	0.998	0.000
F55 Abuse of non-dependence-producing substances	0.001	0.998	0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.001	0.998	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.001	0.998	0.001
F50.8 Other eating disorders	0.001	0.998	0.000
F50.5 Vomiting associated with other psychological disturbances	0.001	0.998	0.000
F50.4 Overeating associated with other psychological disturbances	0.001	0.998	0.000
F50.3 Atypical bulimia nervosa	0.001	0.998	0.000
F50.1 Atypical anorexia nervosa	0.001	0.998	0.000
S32.3 Fracture of ilium	0.001	0.998	0.000
S36.8 Injury of other intra-abdominal organs	0.001	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.001	0.998	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.001	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
G24.3 Spasmodic torticollis	0.002	0.998	0.000
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.998	0.001
T11.9 Unspecified injury of upper limb, level unspecified	0.000	0.998	0.001
T11.8 Other specified injuries of upper limb, level unspecified	0.000	0.998	0.001
T11.6 Traumatic amputation of upper limb, level unspecified	0.000	0.998	0.001
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.000	0.998	0.001
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.000	0.998	0.001
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.000	0.998	0.001
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.000	0.998	0.001
E05.5 Thyroid crisis or storm	0.001	0.998	0.000
E05.4 Thyrotoxicosis factitia	0.001	0.998	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.998	0.000
S36.4 Injury of small intestine	0.001	0.998	0.000
M79.64 Pain in limb (Hand)	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.001	0.998	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.002	0.998	0.000
L03.3 Cellulitis of trunk	0.002	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.001	0.998	0.000
T14 Injury of unspecified body region	0.000	0.998	0.001
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.998	0.000
E10.6 With other specified complications	0.000	0.998	0.001
F50.9 Eating disorder, unspecified	0.001	0.998	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.998	0.001
E10 Insulin-dependent diabetes mellitus	0.000	0.998	0.002
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.998	0.000
L28.0 Lichen simplex chronicus	0.000	0.998	0.001
S36.1 Injury of liver or gallbladder	0.001	0.998	0.000
S36.0 Injury of spleen	0.001	0.998	0.000
K12.0 Recurrent oral aphthae	0.000	0.999	0.001
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.999	0.001
S86 Injury of muscle and tendon at lower leg level	0.000	0.999	0.001
S36.21 Injury of pancreas (with open wound into cavity)	0.001	0.999	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.001	0.999	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.001	0.999	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.001	0.999	0.000
S36.51 Injury of colon (with open wound into cavity)	0.001	0.999	0.000
S36.50 Injury of colon (without open wound into cavity)	0.001	0.999	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.001	0.999	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.001	0.999	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.001	0.999	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.001	0.999	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.001	0.999	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.001	0.999	0.000
G62.8 Other specified polyneuropathies	0.000	0.999	0.001
S32.4 Fracture of acetabulum	0.001	0.999	0.000
S32.31 Fracture of ilium (open)	0.001	0.999	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.001	0.999	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.999	0.001
M24.16 Other articular cartilage disorders (Lower leg)	0.001	0.999	0.000
D32.1 Spinal meninges	0.000	0.999	0.001
G71.1 Myotonic disorders	0.000	0.999	0.001
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.001	0.999	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.000	0.999	0.001
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.001	0.999	0.000
E10.2 With renal complications	0.000	0.999	0.001
H66.3 Other chronic suppurative otitis media	0.000	0.999	0.001
O66.0 Obstructed labour due to shoulder dystocia	0.001	0.999	0.000
K08 Other disorders of teeth and supporting structures	0.001	0.999	0.000
M54.39 Sciatica (Site unspecified)	0.000	0.999	0.001
S36.41 Injury of small intestine (with open wound into cavity)	0.001	0.999	0.000
H49.0 Third [oculomotor] nerve palsy	0.001	0.999	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.001	0.999	0.000
O66.4 Failed trial of labour, unspecified	0.001	0.999	0.000
Z75.2 Other waiting period for investigation and treatment	0.000	0.999	0.001
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.001	0.999	0.000
A40.0 Septicaemia due to streptococcus, group A	0.001	0.999	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.001	0.999	0.000
N87.2 Severe cervical dysplasia, not elsewhere classified	0.001	0.999	0.000
S32.5 Fracture of pubis	0.001	0.999	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.999	0.001
T14.2 Fracture of unspecified body region	0.000	0.999	0.001
T14.8 Other injuries of unspecified body region	0.000	0.999	0.001
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.000	0.999	0.001
T14.5 Injury of blood vessel(s) of unspecified body region	0.000	0.999	0.001
T14.3 Dislocation, sprain and strain of unspecified body region	0.000	0.999	0.001
D32 Benign neoplasm of meninges	0.000	0.999	0.001
S36.01 Injury of spleen (with open wound into cavity)	0.001	0.999	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.001	0.999	0.000
F53.9 Puerperal mental disorder, unspecified	0.001	0.999	0.000
F53.8 Other mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.999	0.000
F53.1 Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.001	0.999	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.001	0.999	0.000
O66 Other obstructed labour	0.001	0.999	0.000
A41.8 Other specified septicaemia	0.000	0.999	0.001
F50.0 Anorexia nervosa	0.001	0.999	0.000
S70.1 Contusion of thigh	0.000	0.999	0.001
S86.0 Injury of Achilles tendon	0.000	0.999	0.001
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.999	0.001
T13.0 Superficial injury of lower limb, level unspecified	0.000	0.999	0.001
T14.1 Open wound of unspecified body region	0.000	0.999	0.001
W49.9 Unspecified place	0.000	0.999	0.001
Z71.3 Dietary counselling and surveillance	0.000	0.999	0.001
E29 Testicular dysfunction	0.000	0.999	0.001
G71 Primary disorders of muscles	0.000	0.999	0.001
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
S32.41 Fracture of acetabulum (open)	0.001	0.999	0.000
G71.0 Muscular dystrophy	0.000	0.999	0.001
H35.6 Retinal haemorrhage	0.000	0.999	0.001
E00-E07 Disorders of thyroid gland	0.001	0.999	0.000
T02.41 Fractures involving multiple regions of both upper limbs (open)	0.000	0.999	0.001
N18.5 Chronic kidney disease, stage 5	0.000	0.999	0.001
T14.4 Injury of nerve(s) of unspecified body region	0.000	0.999	0.001
S36.40 Injury of small intestine (without open wound into cavity)	0.001	0.999	0.000
E10.4 With neurological complications	0.000	0.999	0.001
K08.0 Exfoliation of teeth due to systemic causes	0.001	0.999	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.000	0.999	0.001
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.000	0.999	0.001
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.001	0.999	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.001	0.999	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.001	0.999	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.001	0.999	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations