TreeWAS – Variant ID: rs2518564

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I12.0 Hypertensive renal disease with renal failure	0.000	0.460	0.540
I12 Hypertensive renal disease	0.000	0.774	0.226
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.839	0.161
I12.9 Hypertensive renal disease without renal failure	0.000	0.852	0.148
H74 Other disorders of middle ear and mastoid	0.056	0.944	0.000
H73.8 Other specified disorders of tympanic membrane	0.055	0.945	0.000
H65-H75 Diseases of middle ear and mastoid	0.055	0.945	0.000
H73 Other disorders of tympanic membrane	0.054	0.946	0.000
H70 Mastoiditis and related conditions	0.049	0.951	0.000
H69 Other disorders of Eustachian tube	0.049	0.951	0.000
H65 Nonsuppurative otitis media	0.048	0.952	0.000
H74.0 Tympanosclerosis	0.047	0.953	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.047	0.953	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.047	0.953	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.047	0.953	0.000
H74.4 Polyp of middle ear	0.046	0.954	0.000
H72 Perforation of tympanic membrane	0.045	0.955	0.000
H70.9 Mastoiditis, unspecified	0.045	0.955	0.000
H74.1 Adhesive middle ear disease	0.044	0.956	0.000
I10-I15 Hypertensive diseases	0.000	0.957	0.043
H69.8 Other specified disorders of Eustachian tube	0.042	0.958	0.000
H65.0 Acute serous otitis media	0.041	0.958	0.000
H65.2 Chronic serous otitis media	0.041	0.959	0.000
H72.8 Other perforations of tympanic membrane	0.041	0.959	0.000
H69.9 Eustachian tube disorder, unspecified	0.040	0.960	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.040	0.960	0.000
H67 Otitis media in diseases classified elsewhere	0.040	0.960	0.000
H73.0 Acute myringitis	0.039	0.961	0.000
H68 Eustachian salpingitis and obstruction	0.039	0.961	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.038	0.962	0.000
H73.1 Chronic myringitis	0.038	0.962	0.000
Z45 Adjustment and management of implanted device	0.000	0.962	0.038
H74.8 Other specified disorders of middle ear and mastoid	0.038	0.962	0.000
H70.8 Other mastoiditis and related conditions	0.037	0.962	0.000
H65.4 Other chronic nonsuppurative otitis media	0.037	0.963	0.000
H70.0 Acute mastoiditis	0.037	0.963	0.000
H72.2 Other marginal perforations of tympanic membrane	0.036	0.964	0.000
H65.1 Other acute nonsuppurative otitis media	0.035	0.964	0.000
H70.2 Petrositis	0.035	0.965	0.000
H69.0 Patulous Eustachian tube	0.035	0.965	0.000
I11 Hypertensive heart disease	0.000	0.965	0.035
I34.0 Mitral (valve) insufficiency	0.000	0.966	0.034
I13 Hypertensive heart and renal disease	0.000	0.968	0.032
H65.9 Nonsuppurative otitis media, unspecified	0.032	0.968	0.000
H72.0 Central perforation of tympanic membrane	0.031	0.969	0.000
H72.1 Attic perforation of tympanic membrane	0.031	0.969	0.000
H66 Suppurative and unspecified otitis media	0.030	0.970	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.029	0.971	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.029	0.971	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.029	0.971	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.029	0.971	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.029	0.971	0.000
H70.1 Chronic mastoiditis	0.028	0.971	0.000
Z45.3 Adjustment and management of implanted hearing device	0.000	0.971	0.028
H68.0 Eustachian salpingitis	0.028	0.972	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.000	0.972	0.028
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.972	0.028
H68.1 Obstruction of Eustachian tube	0.027	0.973	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.973	0.027
Z45.2 Adjustment and management of vascular access device	0.000	0.973	0.027
M11.26 Other chondrocalcinosis (Lower leg)	0.027	0.973	0.000
I15 Secondary hypertension	0.000	0.974	0.026
Z45.1 Adjustment and management of infusion pump	0.000	0.974	0.026
H72.9 Perforation of tympanic membrane, unspecified	0.025	0.975	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.975	0.025
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.977	0.023
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.977	0.023
I34 Nonrheumatic mitral valve disorders	0.000	0.977	0.023
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.977	0.022
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.978	0.022
H66.4 Suppurative otitis media, unspecified	0.022	0.978	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.022	0.978	0.000
H65.3 Chronic mucoid otitis media	0.021	0.979	0.000
H66.9 Otitis media, unspecified	0.021	0.979	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.020	0.980	0.000
I15.9 Seconday hypertension, unspecified	0.000	0.981	0.019
I15.2 Hypertension secondary to endocrine disorders	0.000	0.981	0.019
H66.0 Acute suppurative otitis media	0.018	0.981	0.000
H93 Other disorders of ear, not elsewhere classified	0.019	0.981	0.000
I15.0 Renovascular hypertension	0.000	0.982	0.018
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.982	0.018
I15.8 Other secondary hypertension	0.000	0.982	0.018
H93.1 Tinnitus	0.018	0.982	0.000
H66.3 Other chronic suppurative otitis media	0.018	0.982	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.982	0.017
H93.8 Other specified disorders of ear	0.017	0.983	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.983	0.017
H93.9 Disorder of ear, unspecified	0.017	0.983	0.000
M11.2 Other chondrocalcinosis	0.016	0.984	0.000
H93.3 Disorders of acoustic nerve	0.015	0.985	0.000
Chapter VIII Diseases of the ear and mastoid process	0.015	0.985	0.000
H93.2 Other abnormal auditory perceptions	0.015	0.985	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.986	0.014
H93.0 Degenerative and vascular disorders of ear	0.013	0.986	0.000
H90-H95 Other disorders of ear	0.013	0.987	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.013	0.987	0.000
N19 Unspecified renal failure	0.000	0.987	0.013
N05.9 Unspecified	0.000	0.988	0.012
M11.23 Other chondrocalcinosis (Forearm)	0.012	0.988	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.012	0.988	0.000
M11.28 Other chondrocalcinosis (Other)	0.012	0.988	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.012	0.988	0.000
M11.24 Other chondrocalcinosis (Hand)	0.012	0.988	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.012	0.988	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.012	0.988	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.012	0.988	0.000
I34.1 Mitral (valve) prolapse	0.000	0.988	0.012
O47 False labour	0.000	0.988	0.012
N05 Unspecified nephritic syndrome	0.000	0.989	0.011
Z45.8 Adjustment and management of other implanted devices	0.000	0.989	0.011
N05.2 Diffuse membranous glomerulonephritis	0.000	0.989	0.011
H71 Cholesteatoma of middle ear	0.011	0.989	0.000
O47.9 False labour, unspecified	0.000	0.989	0.011
O47.0 False labour before 37 completed weeks of gestation	0.000	0.989	0.011
N05.8 Other	0.000	0.990	0.010
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.000	0.990	0.010
H94 Other disorders of ear in diseases classified elsewhere	0.009	0.990	0.000
N05.1 Focal and segmental glomerular lesions	0.000	0.991	0.009
Z94.0 Kidney transplant status	0.000	0.991	0.009
D89.2 Hypergammaglobulinaemia, unspecified	0.009	0.991	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.009	0.991	0.000
N05.6 Dense deposit disease	0.000	0.992	0.008
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.000	0.992	0.008
N05.0 Minor glomerular abnormality	0.000	0.992	0.008
G55.3 Nerve root and plexus compressions in other dorsopathies	0.008	0.992	0.000
H60-H62 Diseases of external ear	0.008	0.992	0.000
C73 Malignant neoplasm of thyroid gland	0.000	0.992	0.008
H92 Otalgia and effusion of ear	0.008	0.992	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.000	0.992	0.008
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.000	0.992	0.008
G61.0 Guillain-Barre syndrome	0.000	0.993	0.007
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.007	0.993	0.000
G55.0 Nerve root and plexus compressions in neoplastic disease	0.007	0.993	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.007	0.993	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.007	0.993	0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere	0.007	0.993	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.993	0.007
M11 Other crystal arthropathies	0.006	0.993	0.000
H92.2 Otorrhagia	0.006	0.994	0.000
H92.1 Otorrhoea	0.006	0.994	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.006	0.994	0.000
H91 Other hearing loss	0.006	0.994	0.000
H60 Otitis externa	0.006	0.994	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.000	0.995	0.005
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.995	0.005
H95.8 Other postprocedural disorders of ear and mastoid process	0.005	0.995	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.005	0.995	0.000
H91.8 Other specified hearing loss	0.005	0.995	0.000
C74 Malignant neoplasm of adrenal gland	0.000	0.995	0.005
H60.0 Abscess of external ear	0.005	0.995	0.000
H95.1 Other disorders following mastoidectomy	0.005	0.995	0.000
M11.1 Familial chondrocalcinosis	0.005	0.995	0.000
M11.0 Hydroxyapatite deposition disease	0.005	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.000	0.995	0.005
H60.9 Otitis externa, unspecified	0.005	0.995	0.000
L28.0 Lichen simplex chronicus	0.005	0.995	0.000
M11.8 Other specified crystal arthropathies	0.005	0.995	0.000
M11.9 Crystal arthropathy, unspecified	0.005	0.995	0.000
H91.3 Deaf mutism, not elsewhere classified	0.005	0.995	0.000
C74.9 Adrenal gland, unspecified	0.000	0.995	0.005
H60.5 Acute otitis externa, non-infective	0.005	0.995	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.004	0.995	0.000
H60.8 Other otitis externa	0.004	0.995	0.000
C75 Malignant neoplasm of other endocrine glands and related structures	0.000	0.995	0.004
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.996	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.996	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H62.2 Otitis externa in mycoses	0.004	0.996	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.996	0.000
M89.8 Other specified disorders of bone	0.000	0.996	0.004
C74.0 Cortex of adrenal gland	0.000	0.996	0.004
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.996	0.004
H60.2 Malignant otitis externa	0.004	0.996	0.000
Z94 Transplanted organ and tissue status	0.000	0.996	0.004
E87.0 Hyperosmolality and hypernatraemia	0.004	0.996	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.996	0.004
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.996	0.000
H80-H83 Diseases of inner ear	0.004	0.996	0.000
C74.1 Medulla of adrenal gland	0.000	0.996	0.004
I51.8 Other ill-defined heart diseases	0.000	0.996	0.004
C75.9 Endocrine gland, unspecified	0.000	0.996	0.004
Q23.3 Congenital mitral insufficiency	0.000	0.996	0.004
H60.4 Cholesteatoma of external ear	0.004	0.996	0.000
H91.0 Ototoxic hearing loss	0.004	0.996	0.000
H91.2 Sudden idiopathic hearing loss	0.004	0.996	0.000
H92.0 Otalgia	0.004	0.996	0.000
M11.09 Hydroxyapatite deposition disease (Site unspecified)	0.004	0.996	0.000
M11.08 Hydroxyapatite deposition disease (Other)	0.004	0.996	0.000
M11.07 Hydroxyapatite deposition disease (Ankle and foot)	0.004	0.996	0.000
M11.06 Hydroxyapatite deposition disease (Lower leg)	0.004	0.996	0.000
M11.05 Hydroxyapatite deposition disease (Pelvic region and thigh)	0.004	0.996	0.000
M11.04 Hydroxyapatite deposition disease (Hand)	0.004	0.996	0.000
M11.03 Hydroxyapatite deposition disease (Forearm)	0.004	0.996	0.000
M11.02 Hydroxyapatite deposition disease (Upper arm)	0.004	0.996	0.000
M11.01 Hydroxyapatite deposition disease (Shoulder region)	0.004	0.996	0.000
M11.00 Hydroxyapatite deposition disease (Multiple sites)	0.004	0.996	0.000
M11.19 Familial chondrocalcinosis (Site unspecified)	0.004	0.996	0.000
M11.18 Familial chondrocalcinosis (Other)	0.004	0.996	0.000
M11.17 Familial chondrocalcinosis (Ankle and foot)	0.004	0.996	0.000
M11.16 Familial chondrocalcinosis (Lower leg)	0.004	0.996	0.000
M11.15 Familial chondrocalcinosis (Pelvic region and thigh)	0.004	0.996	0.000
M11.14 Familial chondrocalcinosis (Hand)	0.004	0.996	0.000
M11.13 Familial chondrocalcinosis (Forearm)	0.004	0.996	0.000
M11.12 Familial chondrocalcinosis (Upper arm)	0.004	0.996	0.000
M11.11 Familial chondrocalcinosis (Shoulder region)	0.004	0.996	0.000
M11.10 Familial chondrocalcinosis (Multiple sites)	0.004	0.996	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.996	0.004
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.996	0.004
Q23.4 Hypoplastic left heart syndrome	0.000	0.996	0.004
Q23.2 Congenital mitral stenosis	0.000	0.996	0.004
K61.3 Ischiorectal abscess	0.000	0.996	0.004
Z94.4 Liver transplant status	0.000	0.996	0.004
Z73.3 Stress, not elsewhere classified	0.000	0.996	0.004
M11.89 Other specified crystal arthropathies (Site unspecified)	0.003	0.996	0.000
M11.88 Other specified crystal arthropathies (Other)	0.003	0.996	0.000
M11.87 Other specified crystal arthropathies (Ankle and foot)	0.003	0.996	0.000
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)	0.003	0.996	0.000
M11.84 Other specified crystal arthropathies (Hand)	0.003	0.996	0.000
M11.83 Other specified crystal arthropathies (Forearm)	0.003	0.996	0.000
M11.82 Other specified crystal arthropathies (Upper arm)	0.003	0.996	0.000
M11.81 Other specified crystal arthropathies (Shoulder region)	0.003	0.996	0.000
M11.80 Other specified crystal arthropathies (Multiple sites)	0.003	0.996	0.000
C75.0 Parathyroid gland	0.000	0.996	0.004
H60.3 Other infective otitis externa	0.004	0.996	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.003	0.996	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.003	0.996	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.003	0.996	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M11.94 Crystal arthropathy, unspecified (Hand)	0.003	0.996	0.000
M11.93 Crystal arthropathy, unspecified (Forearm)	0.003	0.996	0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.003	0.996	0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.003	0.996	0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.003	0.996	0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere	0.004	0.996	0.000
H61 Other disorders of external ear	0.004	0.996	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.996	0.004
M11.86 Other specified crystal arthropathies (Lower leg)	0.003	0.996	0.000
H91.1 Presbycusis	0.003	0.996	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.996	0.004
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.003	0.996	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.996	0.003
H90 Conductive and sensorineural hearing loss	0.004	0.996	0.000
Z94.5 Skin transplant status	0.000	0.996	0.003
C75.8 Pluriglandular involvement, unspecified	0.000	0.996	0.003
C75.4 Carotid body	0.000	0.996	0.003
C75.3 Pineal gland	0.000	0.996	0.003
C75.2 Craniopharyngeal duct	0.000	0.996	0.003
Z94.6 Bone transplant status	0.000	0.996	0.003
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.996	0.004
M89.0 Algoneurodystrophy	0.000	0.997	0.003
M89 Other disorders of bone	0.000	0.997	0.003
Z94.3 Heart and lungs transplant status	0.000	0.997	0.003
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.997	0.003
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.997	0.003
J35.0 Chronic tonsillitis	0.003	0.997	0.000
C75.5 Aortic body and other paraganglia	0.000	0.997	0.003
Z94.9 Transplanted organ and tissue status, unspecified	0.000	0.997	0.003
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.997	0.003
M89.03 Algoneurodystrophy (Forearm)	0.000	0.997	0.003
M89.83 Other specified disorders of bone (Forearm)	0.000	0.997	0.003
H82 Vertiginous syndromes in diseases classified elsewhere	0.003	0.997	0.000
Z94.8 Other transplanted organ and tissue status	0.000	0.997	0.003
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.997	0.003
Z94.1 Heart transplant status	0.000	0.997	0.003
M89.04 Algoneurodystrophy (Hand)	0.000	0.997	0.003
C75.1 Pituitary gland	0.000	0.997	0.003
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.997	0.003
Z94.2 Lung transplant status	0.000	0.997	0.003
M79.19 Myalgia (Site unspecified)	0.000	0.997	0.003
H60.1 Cellulitis of external ear	0.003	0.997	0.000
Z49.2 Other dialysis	0.000	0.997	0.003
Z49.1 Extracorporeal dialysis	0.000	0.997	0.003
M89.84 Other specified disorders of bone (Hand)	0.000	0.997	0.003
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.997	0.003
Z49.0 Preparatory care for dialysis	0.000	0.997	0.003
M79.11 Myalgia (Shoulder region)	0.000	0.997	0.003
H61.9 Disorder of external ear, unspecified	0.003	0.997	0.000
N17-N19 Renal failure	0.000	0.997	0.003
Z49 Care involving dialysis	0.000	0.997	0.003
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.000	0.997	0.003
H61.2 Impacted cerumen	0.003	0.997	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
M79.1 Myalgia	0.000	0.997	0.003
M89.5 Osteolysis	0.000	0.997	0.003
G61 Inflammatory polyneuropathy	0.000	0.997	0.003
K60.2 Anal fissure, unspecified	0.000	0.997	0.003
M87.9 Osteonecrosis, unspecified	0.000	0.997	0.003
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.997	0.003
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.000	0.997	0.003
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.997	0.003
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.997	0.003
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.997	0.003
M89.6 Osteopathy after poliomyelitis	0.000	0.997	0.003
M89.2 Other disorders of bone development and growth	0.000	0.997	0.003
M89.1 Epiphyseal arrest	0.000	0.997	0.003
N18.0 End-stage renal disease	0.000	0.997	0.003
Z94.7 Corneal transplant status	0.000	0.997	0.003
M89.07 Algoneurodystrophy (Ankle and foot)	0.000	0.997	0.003
H90.0 Conductive hearing loss, bilateral	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.997	0.003
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.997	0.003
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.997	0.003
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
M87 Osteonecrosis	0.000	0.997	0.003
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.997	0.000
C80.9 Malignant neoplasm, unspecified	0.000	0.997	0.003
H61.3 Acquired stenosis of external ear canal	0.003	0.997	0.000
M89.3 Hypertrophy of bone	0.000	0.997	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.997	0.002
M87.98 Osteonecrosis, unspecified (Other)	0.000	0.997	0.002
M47.96 Spondylosis, unspecified (Lumbar region)	0.003	0.997	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.003	0.997	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.000	0.997	0.002
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.997	0.002
M87.2 Osteonecrosis due to previous trauma	0.000	0.997	0.002
H80 Otosclerosis	0.002	0.998	0.001
M79.16 Myalgia (Lower leg)	0.000	0.998	0.002
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.998	0.002
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.998	0.002
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.998	0.002
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.998	0.002
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.998	0.002
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.998	0.002
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.998	0.002
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.998	0.002
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.998	0.002
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.998	0.002
H61.0 Perichondritis of external ear	0.002	0.998	0.000
Q27 Other congenital malformations of peripheral vascular system	0.000	0.998	0.002
M89.88 Other specified disorders of bone (Other)	0.001	0.998	0.002
D40.1 Testis	0.000	0.998	0.002
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.002
M86-M90 Other osteopathies	0.000	0.998	0.002
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.998	0.002
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.000	0.998	0.002
M89.59 Osteolysis (Site unspecified)	0.000	0.998	0.002
M89.58 Osteolysis (Other)	0.000	0.998	0.002
M89.57 Osteolysis (Ankle and foot)	0.000	0.998	0.002
M89.54 Osteolysis (Hand)	0.000	0.998	0.002
M89.53 Osteolysis (Forearm)	0.000	0.998	0.002
M89.52 Osteolysis (Upper arm)	0.000	0.998	0.002
M89.51 Osteolysis (Shoulder region)	0.000	0.998	0.002
M89.50 Osteolysis (Multiple sites)	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
L28 Lichen simplex chronicus and prurigo	0.002	0.998	0.000
N18 Chronic renal failure	0.000	0.998	0.002
M79.17 Myalgia (Ankle and foot)	0.000	0.998	0.002
M79.14 Myalgia (Hand)	0.000	0.998	0.002
M79.13 Myalgia (Forearm)	0.000	0.998	0.002
M79.12 Myalgia (Upper arm)	0.000	0.998	0.002
G61.1 Serum neuropathy	0.000	0.998	0.002
K11.5 Sialolithiasis	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.000	0.998	0.002
M87.94 Osteonecrosis, unspecified (Hand)	0.000	0.998	0.002
M87.93 Osteonecrosis, unspecified (Forearm)	0.000	0.998	0.002
M87.92 Osteonecrosis, unspecified (Upper arm)	0.000	0.998	0.002
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.000	0.998	0.002
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
R29.6 Tendency to fall, not elsewhere classified	0.000	0.998	0.002
K61.1 Rectal abscess	0.000	0.998	0.002
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.998	0.002
M89.18 Epiphyseal arrest (Other)	0.000	0.998	0.002
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.998	0.002
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.998	0.002
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.998	0.002
M89.14 Epiphyseal arrest (Hand)	0.000	0.998	0.002
M89.13 Epiphyseal arrest (Forearm)	0.000	0.998	0.002
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.998	0.002
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.998	0.002
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.998	0.002
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.998	0.002
M89.28 Other disorders of bone development and growth (Other)	0.000	0.998	0.002
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.998	0.002
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.998	0.002
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.998	0.002
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.998	0.002
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.998	0.002
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.998	0.002
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.998	0.002
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.998	0.002
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.998	0.002
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.998	0.002
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.998	0.002
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.998	0.002
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.998	0.002
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.998	0.002
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.998	0.002
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.998	0.002
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.998	0.002
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.998	0.002
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
D62 Acute posthaemorrhagic anaemia	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
G51.0 Bell's palsy	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.998	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.998	0.002
H81 Disorders of vestibular function	0.002	0.998	0.000
M88 Paget's disease of bone [osteitis deformans]	0.000	0.998	0.002
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.000	0.998	0.002
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
M79.18 Myalgia (Other)	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
M87.1 Osteonecrosis due to drugs	0.000	0.998	0.002
M87.0 Idiopathic aseptic necrosis of bone	0.000	0.998	0.002
M89.38 Hypertrophy of bone (Other)	0.000	0.998	0.002
M89.56 Osteolysis (Lower leg)	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.998	0.002
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.998	0.002
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.998	0.002
M89.34 Hypertrophy of bone (Hand)	0.000	0.998	0.002
M89.33 Hypertrophy of bone (Forearm)	0.000	0.998	0.002
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.998	0.002
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.998	0.002
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.998	0.002
L28.1 Prurigo nodularis	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
C26.0 Intestinal tract, part unspecified	0.000	0.998	0.002
M87.3 Other secondary osteonecrosis	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.000	0.998	0.002
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.998	0.002
H80.8 Other otosclerosis	0.002	0.998	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.998	0.002
M87.96 Osteonecrosis, unspecified (Lower leg)	0.000	0.998	0.002
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.000	0.998	0.002
M87.28 Osteonecrosis due to previous trauma (Other)	0.000	0.998	0.002
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.000	0.998	0.002
M87.24 Osteonecrosis due to previous trauma (Hand)	0.000	0.998	0.002
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.000	0.998	0.002
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.000	0.998	0.002
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.000	0.998	0.002
N18.9 Chronic renal failure, unspecified	0.000	0.998	0.002
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
K61 Abscess of anal and rectal regions	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.000	0.998	0.002
H80.2 Cochlear otosclerosis	0.002	0.998	0.001
H80.1 Otosclerosis involving oval window, obliterative	0.002	0.998	0.001
N18.2 Chronic kidney disease, stage 2	0.000	0.998	0.002
H83 Other diseases of inner ear	0.002	0.998	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.998	0.002
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
M87.8 Other osteonecrosis	0.000	0.998	0.002
Q27.1 Congenital renal artery stenosis	0.000	0.998	0.002
Q27.4 Congenital phlebectasia	0.000	0.998	0.002
Q27.2 Other congenital malformations of renal artery	0.000	0.998	0.002
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.998	0.002
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
Z52.4 Kidney donor	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.000	0.998	0.002
H80.0 Otosclerosis involving oval window, nonobliterative	0.001	0.998	0.001
K11.7 Disturbances of salivary secretion	0.002	0.998	0.000
K29.3 Chronic superficial gastritis	0.000	0.998	0.002
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.998	0.002
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
K61.2 Anorectal abscess	0.000	0.998	0.002
M62.8 Other specified disorders of muscle	0.000	0.998	0.002
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.998	0.002
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.998	0.002
Q28.1 Other malformations of precerebral vessels	0.000	0.998	0.002
K11.1 Hypertrophy of salivary gland	0.002	0.998	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.000	0.998	0.002
Q25.4 Other congenital malformations of aorta	0.000	0.998	0.002
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.998	0.002
M88.0 Paget's disease of skull	0.000	0.998	0.002
N18.1 Chronic kidney disease, stage 1	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.000	0.998	0.002
K11 Diseases of salivary glands	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.998	0.002
H83.9 Disease of inner ear, unspecified	0.002	0.998	0.000
L28.2 Other prurigo	0.002	0.998	0.000
M88.8 Paget's disease of other bones	0.000	0.998	0.002
N18.8 Other chronic renal failure	0.000	0.998	0.002
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.998	0.002
Z40.8 Other prophylactic surgery	0.000	0.998	0.002
M90 Osteopathies in diseases classified elsewhere	0.000	0.998	0.002
M25.50 Pain in joint (Multiple sites)	0.000	0.998	0.002
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.000	0.998	0.002
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.002	0.998	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.000	0.998	0.002
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.000	0.998	0.002
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.000	0.998	0.002
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.000	0.998	0.002
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.000	0.998	0.002
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.000	0.998	0.002
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.000	0.998	0.002
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.000	0.998	0.002
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations