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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs2523477
log Bayes Factor = 6.40206
Chromosome 6   position 31,360,389  (GRCh37) Explore rs2523477 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.005 0.995
E00-E07 Disorders of thyroid gland
0.000 0.007 0.993
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.009 0.991
Chapter XII Diseases of the skin and subcutaneous tissue
0.000 0.026 0.974
E65-E68 Obesity and other hyperalimentation
0.000 0.026 0.974
L40-L45 Papulosquamous disorders
0.000 0.030 0.970
L40 Psoriasis
0.000 0.030 0.970
# Top node
0.000 0.035 0.965
E66 Obesity
0.000 0.037 0.963
L40.5 Arthropathic psoriasis
0.000 0.038 0.962
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.000 0.039 0.961
E66.8 Other obesity
0.000 0.039 0.961
M06.9 Rheumatoid arthritis, unspecified
0.000 0.040 0.960
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.000 0.041 0.959
M06 Other rheumatoid arthritis
0.000 0.046 0.954
D50-D53 Nutritional anaemias
0.000 0.048 0.952
M05-M14 Inflammatory polyarthropathies
0.000 0.048 0.952
D50 Iron deficiency anaemia
0.000 0.049 0.951
L57 Skin changes due to chronic exposure to nonionising radiation
0.000 0.049 0.951
D50.9 Iron deficiency anaemia, unspecified
0.000 0.051 0.949
L40.9 Psoriasis, unspecified
0.000 0.051 0.949
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.053 0.947
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.053 0.947
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.000 0.054 0.946
L57.0 Actinic keratosis
0.000 0.071 0.929
L00-L08 Infections of the skin and subcutaneous tissue
0.000 0.079 0.921
L20-L30 Dermatitis and eczema
0.000 0.087 0.913
Chapter I Certain infectious and parasitic diseases
0.000 0.094 0.906
E06 Thyroiditis
0.000 0.097 0.903
Chapter VIII Diseases of the ear and mastoid process
0.000 0.098 0.902
L02 Cutaneous abscess, furuncle and carbuncle
0.000 0.104 0.896
B35-B49 Mycoses
0.000 0.104 0.896
B37 Candidiasis
0.000 0.106 0.894
B37.8 Candidiasis of other sites
0.000 0.108 0.892
M07 Psoriatic and enteropathic arthropathies
0.000 0.117 0.883
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.000 0.119 0.881
Chapter V Mental and behavioural disorders
0.000 0.124 0.876
L57.8 Other skin changes due to chronic exposure to nonionising radiation
0.000 0.133 0.867
M45-M49 Spondylopathies
0.000 0.137 0.863
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.137 0.863
M45 Ankylosing spondylitis
0.000 0.147 0.853
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.000 0.147 0.853
H65-H75 Diseases of middle ear and mastoid
0.000 0.151 0.849
B25-B34 Other viral diseases
0.000 0.156 0.844
M45.X9 Ankylosing spondylitis (Site unspecified)
0.000 0.160 0.840
M07.3 Other psoriatic arthropathies
0.000 0.166 0.834
B37.0 Candidal stomatitis
0.000 0.168 0.832
L29 Pruritus
0.000 0.169 0.831
E06.3 Autoimmune thyroiditis
0.000 0.173 0.827
H72 Perforation of tympanic membrane
0.000 0.175 0.825
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.175 0.825
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.000 0.182 0.818
M05 Seropositive rheumatoid arthritis
0.000 0.184 0.816
H80-H83 Diseases of inner ear
0.000 0.185 0.815
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.189 0.810
H72.9 Perforation of tympanic membrane, unspecified
0.000 0.190 0.810
E70-E90 Metabolic disorders
0.000 0.197 0.803
M95.0 Acquired deformity of nose
0.000 0.202 0.798
B34 Viral infection of unspecified site
0.000 0.204 0.796
L29.0 Pruritus ani
0.000 0.206 0.794
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.208 0.792
D68 Other coagulation defects
0.000 0.218 0.782
E20-E35 Disorders of other endocrine glands
0.000 0.218 0.782
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.223 0.777
H65 Nonsuppurative otitis media
0.000 0.224 0.776
D80-D89 Certain disorders involving the immune mechanism
0.000 0.232 0.768
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.239 0.761
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.239 0.761
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.241 0.759
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.242 0.758
M06.0 Seronegative rheumatoid arthritis
0.000 0.246 0.754
L30 Other dermatitis
0.000 0.247 0.753
B20-B24 Human immunodeficiency virus [HIV] disease
0.000 0.248 0.752
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.000 0.248 0.752
B34.9 Viral infection, unspecified
0.000 0.251 0.749
M35 Other systemic involvement of connective tissue
0.000 0.251 0.749
E27 Other disorders of adrenal gland
0.000 0.252 0.748
M35.3 Polymyalgia rheumatica
0.000 0.253 0.747
M20-M25 Other joint disorders
0.000 0.254 0.746
L08 Other local infections of skin and subcutaneous tissue
0.000 0.256 0.744
D55-D59 Haemolytic anaemias
0.000 0.264 0.736
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.266 0.734
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.266 0.734
B35 Dermatophytosis
0.000 0.267 0.733
H80 Otosclerosis
0.000 0.270 0.730
E27.1 Primary adrenocortical insufficiency
0.000 0.275 0.725
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.276 0.724
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.000 0.276 0.724
E10-E14 Diabetes mellitus
0.000 0.279 0.721
L56 Other acute skin changes due to ultraviolet radiation
0.000 0.280 0.720
L27 Dermatitis due to substances taken internally
0.000 0.281 0.719
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.281 0.719
M00-M03 Infectious arthropathies
0.000 0.281 0.719
B99-B99 Other infectious diseases
0.000 0.283 0.717
F30-F39 Mood [affective] disorders
0.000 0.286 0.714
E03.5 Myxoedema coma
0.000 0.287 0.713
E03.4 Atrophy of thyroid (acquired)
0.000 0.287 0.713
E03.3 Postinfectious hypothyroidism
0.000 0.287 0.713
E03.1 Congenital hypothyroidism without goitre
0.000 0.287 0.713
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.287 0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.712
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.288 0.712
E66.0 Obesity due to excess calories
0.000 0.291 0.709
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.294 0.706
E67 Other hyperalimentation
0.000 0.302 0.698
E68 Sequelae of hyperalimentation
0.000 0.302 0.698
D86 Sarcoidosis
0.000 0.303 0.697
L05 Pilonidal cyst
0.000 0.303 0.697
L44 Other papulosquamous disorders
0.000 0.304 0.696
L41 Parapsoriasis
0.000 0.304 0.696
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.304 0.696
L40.8 Other psoriasis
0.000 0.304 0.696
L40.4 Guttate psoriasis
0.000 0.304 0.696
L40.3 Pustulosis palmaris et plantaris
0.000 0.304 0.696
L40.2 Acrodermatitis continua
0.000 0.304 0.696
L40.1 Generalised pustular psoriasis
0.000 0.304 0.696
E50-E64 Other nutritional deficiencies
0.000 0.305 0.695
Chapter XVI Certain conditions originating in the perinatal period
0.000 0.308 0.692
E66.1 Drug-induced obesity
0.000 0.309 0.691
L59 Other disorders of skin and subcutaneous tissue related to radiation
0.000 0.311 0.689
L58 Radiodermatitis
0.000 0.311 0.689
L55 Sunburn
0.000 0.311 0.689
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.312 0.688
E06.9 Thyroiditis, unspecified
0.000 0.313 0.686
M14 Arthropathies in other diseases classified elsewhere
0.000 0.315 0.685
M06.8 Other specified rheumatoid arthritis
0.000 0.316 0.684
M06.2 Rheumatoid bursitis
0.000 0.316 0.684
M06.1 Adult-onset Still's disease
0.000 0.316 0.684
F60-F69 Disorders of adult personality and behaviour
0.000 0.316 0.684
F80-F89 Disorders of psychological development
0.000 0.317 0.683
A50-A64 Infections with a predominantly sexual mode of transmission
0.000 0.317 0.683
H72.0 Central perforation of tympanic membrane
0.000 0.317 0.683
M12 Other specific arthropathies
0.000 0.317 0.682
M09 Juvenile arthritis in diseases classified elsewhere
0.000 0.317 0.682
M08 Juvenile arthritis
0.000 0.317 0.682
D50.1 Sideropenic dysphagia
0.000 0.318 0.682
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.000 0.318 0.682
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified
0.000 0.318 0.682
L57.5 Actinic granuloma
0.000 0.318 0.682
L57.3 Poikiloderma of Civatte
0.000 0.318 0.682
L57.2 Cutis rhomboidalis nuchae
0.000 0.318 0.682
L57.1 Actinic reticuloid
0.000 0.318 0.682
H83 Other diseases of inner ear
0.000 0.320 0.680
D68.5 Primary Thrombophilia
0.000 0.322 0.678
Chapter XXII Codes for special purposes
0.000 0.322 0.678
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.326 0.674
H65.9 Nonsuppurative otitis media, unspecified
0.000 0.330 0.670
L28 Lichen simplex chronicus and prurigo
0.000 0.331 0.669
H80.9 Otosclerosis, unspecified
0.000 0.331 0.669
E10 Insulin-dependent diabetes mellitus
0.000 0.333 0.667
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.333 0.667
L04 Acute lymphadenitis
0.000 0.340 0.660
L01 Impetigo
0.000 0.340 0.660
L00 Staphylococcal scalded skin syndrome
0.000 0.340 0.660
E03.8 Other specified hypothyroidism
0.000 0.340 0.659
D68.9 Coagulation defect, unspecified
0.000 0.341 0.659
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.341 0.659
L57.4 Cutis laxa senilis
0.000 0.344 0.656
E65 Localised adiposity
0.000 0.346 0.654
L24 Irritant contact dermatitis
0.000 0.346 0.654
L21 Seborrhoeic dermatitis
0.000 0.346 0.654
L26 Exfoliative dermatitis
0.000 0.346 0.654
L22 Diaper [napkin] dermatitis
0.000 0.346 0.654
F42 Obsessive-compulsive disorder
0.000 0.346 0.654
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.000 0.351 0.649
A75-A79 Rickettsioses
0.000 0.351 0.649
A70-A74 Other diseases caused by chlamydiae
0.000 0.351 0.649
A65-A69 Other spirochaetal diseases
0.000 0.351 0.649
A20-A28 Certain zoonotic bacterial diseases
0.000 0.351 0.649
L10-L14 Bullous disorders
0.000 0.352 0.648
L20 Atopic dermatitis
0.000 0.352 0.648
F31 Bipolar affective disorder
0.000 0.352 0.648
E06.5 Other chronic thyroiditis
0.000 0.353 0.647
E06.4 Drug-induced thyroiditis
0.000 0.353 0.647
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.353 0.647
E06.1 Subacute thyroiditis
0.000 0.353 0.647
E06.0 Acute thyroiditis
0.000 0.353 0.647
E89.0 Postprocedural hypothyroidism
0.000 0.353 0.647
E40-E46 Malnutrition
0.000 0.355 0.645
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites
0.000 0.357 0.643
B48 Other mycoses, not elsewhere classified
0.000 0.357 0.642
B47 Mycetoma
0.000 0.357 0.642
B46 Zygomycosis
0.000 0.357 0.642
B45 Cryptococcosis
0.000 0.357 0.642
B43 Chromomycosis and phaeomycotic abscess
0.000 0.357 0.642
B42 Sporotrichosis
0.000 0.357 0.642
B41 Paracoccidioidomycosis
0.000 0.357 0.642
B40 Blastomycosis
0.000 0.357 0.642
B39 Histoplasmosis
0.000 0.357 0.642
B38 Coccidioidomycosis
0.000 0.357 0.642
B36 Other superficial mycoses
0.000 0.357 0.642
B24 Unspecified human immunodeficiency virus [HIV] disease
0.000 0.358 0.642
B34.8 Other viral infections of unspecified site
0.000 0.359 0.641
B37.7 Candidal septicaemia
0.000 0.359 0.641
B37.6 Candidal endocarditis
0.000 0.359 0.641
B37.5 Candidal meningitis
0.000 0.359 0.641
M11 Other crystal arthropathies
0.000 0.359 0.641
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.359 0.641
M35.0 Sicca syndrome [Sjogren]
0.000 0.361 0.638
L25 Unspecified contact dermatitis
0.000 0.363 0.637
E73 Lactose intolerance
0.000 0.364 0.636
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.365 0.635
F05 Delirium, not induced by alcohol and other psychoactive substances
0.000 0.366 0.634
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.366 0.633
M07.6 Other enteropathic arthropathies
0.000 0.367 0.633
M07.5 Arthropathy in ulcerative colitis
0.000 0.367 0.633
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.000 0.367 0.633
M07.2 Psoriatic spondylitis
0.000 0.367 0.633
M07.1 Arthritis mutilans
0.000 0.367 0.633
M07.0 Distal interphalangeal psoriatic arthropathy
0.000 0.367 0.633
D86.9 Sarcoidosis, unspecified
0.000 0.369 0.631
D52 Folate deficiency anaemia
0.000 0.370 0.630
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.371 0.628
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified
0.000 0.372 0.628
H60-H62 Diseases of external ear
0.000 0.373 0.627
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.000 0.373 0.627
H73 Other disorders of tympanic membrane
0.000 0.374 0.626
B50-B64 Protozoal diseases
0.000 0.375 0.625
B25 Cytomegaloviral disease
0.000 0.377 0.623
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.000 0.377 0.623
A15-A19 Tuberculosis
0.000 0.379 0.621
M46 Other inflammatory spondylopathies
0.000 0.379 0.621
L23 Allergic contact dermatitis
0.000 0.380 0.620
L29.9 Pruritus, unspecified
0.000 0.381 0.619
L30.8 Other specified dermatitis
0.000 0.381 0.619
M99 Biomechanical lesions, not elsewhere classified
0.000 0.381 0.619
D51 Vitamin B12 deficiency anaemia
0.000 0.381 0.619
F43 Reaction to severe stress, and adjustment disorders
0.000 0.385 0.615
B90-B94 Sequelae of infectious and parasitic diseases
0.000 0.385 0.615
M35.7 Hypermobility syndrome
0.000 0.385 0.615
E88 Other metabolic disorders
0.000 0.385 0.615
M06.3 Rheumatoid nodule
0.000 0.385 0.615
D50.8 Other iron deficiency anaemias
0.000 0.386 0.614
H65.2 Chronic serous otitis media
0.000 0.387 0.613
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.000 0.388 0.612
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.000 0.388 0.612
M45.X6 Ankylosing spondylitis (Lumbar region)
0.000 0.388 0.612
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.000 0.388 0.612
M45.X4 Ankylosing spondylitis (Thoracic region)
0.000 0.388 0.612
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.000 0.388 0.612
M45.X2 Ankylosing spondylitis (Cervical region)
0.000 0.388 0.612
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.000 0.388 0.612
D67 Hereditary factor IX deficiency
0.000 0.388 0.611
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.000 0.388 0.611
H65.3 Chronic mucoid otitis media
0.000 0.388 0.612
B37.9 Candidiasis, unspecified
0.000 0.389 0.611
D66 Hereditary factor VIII deficiency
0.000 0.389 0.611
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.000 0.391 0.609
H68 Eustachian salpingitis and obstruction
0.000 0.391 0.609
H67 Otitis media in diseases classified elsewhere
0.000 0.391 0.609
B27 Infectious mononucleosis
0.000 0.392 0.608
F70-F79 Mental retardation
0.000 0.392 0.608
F20 Schizophrenia
0.000 0.394 0.606
M06.4 Inflammatory polyarthropathy
0.000 0.394 0.606
B33 Other viral diseases, not elsewhere classified
0.000 0.395 0.605
B30 Viral conjunctivitis
0.000 0.395 0.605
B26 Mumps
0.000 0.395 0.605
M34 Systemic sclerosis
0.000 0.395 0.605
B35.1 Tinea unguium
0.000 0.395 0.605
M49 Spondylopathies in diseases classified elsewhere
0.000 0.396 0.604
M60-M63 Disorders of muscles
0.000 0.396 0.603
B65-B83 Helminthiases
0.000 0.397 0.603
H70 Mastoiditis and related conditions
0.000 0.397 0.603
L05.0 Pilonidal cyst with abscess
0.000 0.399 0.601
D59 Acquired haemolytic anaemia
0.000 0.399 0.601
L42 Pityriasis rosea
0.000 0.400 0.600
M91-M94 Chondropathies
0.000 0.400 0.600
M07.38 Other psoriatic arthropathies (Other)
0.000 0.402 0.598
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.402 0.598
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.402 0.598
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.402 0.598
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.402 0.598
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.402 0.598
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.402 0.598
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.402 0.598
F42.9 Obsessive-compulsive disorder, unspecified
0.000 0.404 0.596
L29.8 Other pruritus
0.000 0.404 0.596
L29.3 Anogenital pruritus, unspecified
0.000 0.404 0.596
L29.1 Pruritus scroti
0.000 0.404 0.596
E22 Hyperfunction of pituitary gland
0.000 0.404 0.596
E07 Other disorders of thyroid
0.000 0.404 0.595
F40 Phobic anxiety disorders
0.000 0.405 0.595
L27.0 Generalised skin eruption due to drugs and medicaments
0.000 0.406 0.594
D69 Purpura and other haemorrhagic conditions
0.000 0.407 0.593
H72.1 Attic perforation of tympanic membrane
0.000 0.408 0.592
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.408 0.592
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.408 0.592
M95.5 Acquired deformity of pelvis
0.000 0.408 0.592
M95.4 Acquired deformity of chest and rib
0.000 0.408 0.592
M95.3 Acquired deformity of neck
0.000 0.408 0.592
M95.2 Other acquired deformity of head
0.000 0.408 0.592
M95.1 Cauliflower ear
0.000 0.408 0.592
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.409 0.591
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.410 0.590
B15-B19 Viral hepatitis
0.000 0.410 0.590
E86 Volume depletion
0.000 0.410 0.590
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.410 0.590
B85-B89 Pediculosis, acariasis and other infestations
0.000 0.411 0.589
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.000 0.414 0.586
B37.2 Candidiasis of skin and nail
0.000 0.414 0.585
M05.8 Other seropositive rheumatoid arthritis
0.000 0.415 0.585
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.000 0.415 0.585
M05.2 Rheumatoid vasculitis
0.000 0.415 0.585
M05.1 Rheumatoid lung disease
0.000 0.415 0.585
M05.0 Felty's syndrome
0.000 0.415 0.585
D86.0 Sarcoidosis of lung
0.000 0.416 0.584
B37.1 Pulmonary candidiasis
0.000 0.416 0.584
H82 Vertiginous syndromes in diseases classified elsewhere
0.000 0.416 0.584
H65.4 Other chronic nonsuppurative otitis media
0.000 0.416 0.584
E10.9 Without complications
0.000 0.416 0.584
H83.0 Labyrinthitis
0.000 0.417 0.583
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.417 0.583
E74 Other disorders of carbohydrate metabolism
0.000 0.418 0.582
B99 Other and unspecified infectious diseases
0.000 0.419 0.581
F22 Persistent delusional disorders
0.000 0.419 0.581
D68.2 Hereditary deficiency of other clotting factors
0.000 0.421 0.579
D68.0 Von Willebrand's disease
0.000 0.422 0.578
F00 Dementia in Alzheimer's disease
0.000 0.424 0.576
E84 Cystic fibrosis
0.000 0.424 0.576
E79 Disorders of purine and pyrimidine metabolism
0.000 0.424 0.576
E77 Disorders of glycoprotein metabolism
0.000 0.424 0.576
E76 Disorders of glycosaminoglycan metabolism
0.000 0.424 0.576
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.424 0.576
E72 Other disorders of amino-acid metabolism
0.000 0.424 0.576
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.424 0.576
E70 Disorders of aromatic amino-acid metabolism
0.000 0.424 0.576
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.424 0.576
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.427 0.573
F99-F99 Unspecified mental disorder
0.000 0.428 0.572
L30.9 Dermatitis, unspecified
0.000 0.428 0.572
B34.3 Parvovirus infection, unspecified
0.000 0.429 0.571
B34.2 Coronavirus infection, unspecified
0.000 0.429 0.571
B34.1 Enterovirus infection, unspecified
0.000 0.429 0.571
B34.0 Adenovirus infection, unspecified
0.000 0.429 0.571
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.430 0.570
F30 Manic episode
0.000 0.431 0.569
F25 Schizoaffective disorders
0.000 0.431 0.568
L43 Lichen planus
0.000 0.432 0.568
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.433 0.567
F23 Acute and transient psychotic disorders
0.000 0.433 0.567
B37.4 Candidiasis of other urogenital sites
0.000 0.433 0.567
M80-M85 Disorders of bone density and structure
0.001 0.436 0.562
D53 Other nutritional anaemias
0.000 0.438 0.562
D68.4 Acquired coagulation factor deficiency
0.000 0.439 0.561
D68.1 Hereditary factor XI deficiency
0.000 0.439 0.561
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.439 0.561
F03 Unspecified dementia
0.000 0.439 0.561
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.439 0.560
E32 Diseases of thymus
0.000 0.439 0.560
E31 Polyglandular dysfunction
0.000 0.439 0.560
E30 Disorders of puberty, not elsewhere classified
0.000 0.439 0.560
E25 Adrenogenital disorders
0.000 0.439 0.560
E20 Hypoparathyroidism
0.000 0.439 0.560
F05.9 Delirium, unspecified
0.000 0.440 0.560
L40.0 Psoriasis vulgaris
0.000 0.440 0.559
L50-L54 Urticaria and erythema
0.000 0.441 0.559
H65.1 Other acute nonsuppurative otitis media
0.000 0.443 0.557
H65.0 Acute serous otitis media
0.000 0.443 0.557
M00 Pyogenic arthritis
0.000 0.444 0.556
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.444 0.555
F45 Somatoform disorders
0.000 0.446 0.554
B34.4 Papovirus infection, unspecified
0.000 0.447 0.553
D84 Other immunodeficiencies
0.000 0.449 0.550
D83 Common variable immunodeficiency
0.000 0.449 0.550
D82 Immunodeficiency associated with other major defects
0.000 0.449 0.550
D81 Combined immunodeficiencies
0.000 0.449 0.550
E10.3 With ophthalmic complications
0.000 0.450 0.550
F60 Specific personality disorders
0.000 0.450 0.550
L02.0 Cutaneous abscess, furuncle and carbuncle of face
0.000 0.452 0.548
F01 Vascular dementia
0.000 0.453 0.547
L56.8 Other specified acute skin changes due to ultraviolet radiation
0.000 0.453 0.547
E05.5 Thyroid crisis or storm
0.000 0.454 0.546
E05.4 Thyrotoxicosis factitia
0.000 0.454 0.546
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.454 0.546
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.454 0.546
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.000 0.454 0.546
F09 Unspecified organic or symptomatic mental disorder
0.000 0.454 0.546
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.000 0.454 0.546
H69 Other disorders of Eustachian tube
0.000 0.455 0.544
F39 Unspecified mood [affective] disorder
0.000 0.457 0.543
B35.3 Tinea pedis
0.000 0.457 0.543
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.000 0.457 0.543
M30 Polyarteritis nodosa and related conditions
0.000 0.457 0.543
F81 Specific developmental disorders of scholastic skills
0.000 0.458 0.542
F02 Dementia in other diseases classified elsewhere
0.000 0.458 0.542
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.459 0.541
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.459 0.541
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.459 0.541
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.459 0.541
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.459 0.541
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.459 0.541
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.459 0.541
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.459 0.541
E14 Unspecified diabetes mellitus
0.000 0.460 0.540
M10 Gout
0.000 0.460 0.540
L30.5 Pityriasis alba
0.000 0.460 0.540
L30.4 Erythema intertrigo
0.000 0.460 0.540
L30.3 Infective dermatitis
0.000 0.460 0.540
L30.2 Cutaneous autosensitisation
0.000 0.460 0.540
L30.1 Dyshidrosis [pompholyx]
0.000 0.460 0.540
L30.0 Nummular dermatitis
0.000 0.460 0.540
E26 Hyperaldosteronism
0.000 0.460 0.540
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.000 0.461 0.539
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.000 0.461 0.539
B21 Human immunodeficiency virus [HIV] disease resulting in malignant neoplasms
0.000 0.461 0.539
B20 Human immunodeficiency virus [HIV] disease resulting in infectious and parasitic diseases
0.000 0.461 0.539
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.462 0.538
M22 Disorders of patella
0.000 0.462 0.538
M35.9 Systemic involvement of connective tissue, unspecified
0.000 0.463 0.537
M35.8 Other specified systemic involvement of connective tissue
0.000 0.463 0.537
M35.6 Relapsing panniculitis [Weber-Christian]
0.000 0.463 0.537
M35.5 Multifocal fibrosclerosis
0.000 0.463 0.537
M35.4 Diffuse (eosinophilic) fasciitis
0.000 0.463 0.537
M35.2 Behcet's disease
0.000 0.463 0.537
M35.1 Other overlap syndromes
0.000 0.463 0.537
E85 Amyloidosis
0.000 0.463 0.537
E27.5 Adrenomedullary hyperfunction
0.000 0.463 0.536
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.463 0.536
E27.2 Addisonian crisis
0.000 0.463 0.536
E27.0 Other adrenocortical overactivity
0.000 0.463 0.536
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.000 0.465 0.535
M32 Systemic lupus erythematosus
0.000 0.465 0.535
E10.1 With ketoacidosis
0.000 0.466 0.534
L08.1 Erythrasma
0.000 0.466 0.534
L08.0 Pyoderma
0.000 0.466 0.534
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.000 0.467 0.533
E27.9 Disorder of adrenal gland, unspecified
0.000 0.469 0.531
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.000 0.470 0.530
L28.0 Lichen simplex chronicus
0.000 0.470 0.530
E53 Deficiency of other B group vitamins
0.000 0.471 0.529
D57 Sickle-cell disorders
0.000 0.472 0.528
D56 Thalassaemia
0.000 0.472 0.528
D55 Anaemia due to enzyme disorders
0.000 0.472 0.528
D68.6 Other Thrombophilia
0.000 0.472 0.528
M80 Osteoporosis with pathological fracture
0.001 0.473 0.526
F48 Other neurotic disorders
0.000 0.473 0.526
F28 Other nonorganic psychotic disorders
0.000 0.474 0.526
F24 Induced delusional disorder
0.000 0.474 0.526
F21 Schizotypal disorder
0.000 0.474 0.526
B35.9 Dermatophytosis, unspecified
0.000 0.474 0.525
B35.8 Other dermatophytoses
0.000 0.474 0.525
B35.6 Tinea cruris
0.000 0.474 0.525
B35.5 Tinea imbricata
0.000 0.474 0.525
B35.4 Tinea corporis
0.000 0.474 0.525
B35.2 Tinea manuum
0.000 0.474 0.525
B35.0 Tinea barbae and tinea capitis
0.000 0.474 0.525
L08.8 Other specified local infections of skin and subcutaneous tissue
0.000 0.475 0.525
H81 Disorders of vestibular function
0.000 0.476 0.524
H80.8 Other otosclerosis
0.000 0.477 0.523
H80.2 Cochlear otosclerosis
0.000 0.477 0.523
H80.1 Otosclerosis involving oval window, obliterative
0.000 0.477 0.523
H80.0 Otosclerosis involving oval window, nonobliterative
0.000 0.477 0.523
M13 Other arthritis
0.000 0.477 0.523
E34 Other endocrine disorders
0.000 0.481 0.519
E10.5 With peripheral circulatory complications
0.000 0.482 0.518
E12 Malnutrition-related diabetes mellitus
0.000 0.483 0.517
L56.9 Acute skin change due to ultraviolet radiation, unspecified
0.000 0.484 0.516
L56.4 Polymorphous light eruption
0.000 0.484 0.516
L56.3 Solar urticaria
0.000 0.484 0.516
L56.2 Photocontact dermatitis [berloque dermatitis]
0.000 0.484 0.516
L56.1 Drug photoallergic response
0.000 0.484 0.516
L56.0 Drug phototoxic response
0.000 0.484 0.516
E73.9 Lactose intolerance, unspecified
0.000 0.484 0.516
H72.2 Other marginal perforations of tympanic membrane
0.000 0.484 0.515
L27.9 Dermatitis due to unspecified substance taken internally
0.000 0.485 0.515
L27.8 Dermatitis due to other substances taken internally
0.000 0.485 0.515
L27.2 Dermatitis due to ingested food
0.000 0.485 0.515
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.485 0.515
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.485 0.515
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.485 0.515
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.485 0.515
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.485 0.515
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.485 0.515
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.485 0.515
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.000 0.485 0.515
M02 Reactive arthropathies
0.000 0.485 0.515
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.000 0.485 0.515
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.000 0.485 0.515
M46.9 Inflammatory spondylopathy, unspecified
0.000 0.485 0.515
E28 Ovarian dysfunction
0.000 0.486 0.514
F38 Other mood [affective] disorders
0.000 0.488 0.512
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.000 0.488 0.511
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.490 0.510
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.490 0.510
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.490 0.510
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.490 0.510
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.490 0.510
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.490 0.510
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.490 0.510
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.490 0.510
R21 Rash and other nonspecific skin eruption
0.000 0.491 0.509
H72.8 Other perforations of tympanic membrane
0.000 0.491 0.509
B37.3 Candidiasis of vulva and vagina
0.000 0.493 0.507
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.493 0.506
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.493 0.506
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.493 0.506
E89.5 Postprocedural testicular hypofunction
0.000 0.493 0.506
E89.4 Postprocedural ovarian failure
0.000 0.493 0.506

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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