TreeWAS – Variant ID: rs2548621

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D10-D36 Benign neoplasms	0.184	0.816	0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.182	0.818	0.000
D17 Benign lipomatous neoplasm	0.176	0.824	0.000
D12.4 Descending colon	0.168	0.832	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.167	0.833	0.000
D12.3 Transverse colon	0.166	0.834	0.000
D22 Melanocytic naevi	0.164	0.836	0.000
D12.7 Rectosigmoid junction	0.161	0.839	0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.159	0.841	0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.158	0.842	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.151	0.849	0.000
D12.2 Ascending colon	0.150	0.850	0.000
D22.4 Melanocytic naevi of scalp and neck	0.149	0.851	0.000
D23 Other benign neoplasms of skin	0.147	0.853	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.146	0.854	0.000
D16 Benign neoplasm of bone and articular cartilage	0.145	0.855	0.000
D25 Leiomyoma of uterus	0.144	0.856	0.000
D27 Benign neoplasm of ovary	0.144	0.856	0.000
D28 Benign neoplasm of other and unspecified female genital organs	0.143	0.857	0.000
D12.6 Colon, unspecified	0.143	0.857	0.000
D13.1 Stomach	0.142	0.858	0.000
D21 Other benign neoplasms of connective and other soft tissue	0.142	0.858	0.000
D11 Benign neoplasm of major salivary glands	0.141	0.859	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.140	0.860	0.000
D12.1 Appendix	0.138	0.862	0.000
D31 Benign neoplasm of eye and adnexa	0.138	0.862	0.000
D30 Benign neoplasm of urinary organs	0.136	0.864	0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.134	0.865	0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.134	0.866	0.000
D22.5 Melanocytic naevi of trunk	0.134	0.866	0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.133	0.867	0.000
D18 Haemangioma and lymphangioma, any site	0.132	0.868	0.000
D12.5 Sigmoid colon	0.132	0.868	0.000
D32 Benign neoplasm of meninges	0.132	0.868	0.000
D19 Benign neoplasm of mesothelial tissue	0.132	0.868	0.000
D22.2 Melanocytic naevi of ear and external auricular canal	0.130	0.870	0.000
D23.1 Skin of eyelid, including canthus	0.129	0.871	0.000
D29 Benign neoplasm of male genital organs	0.129	0.871	0.000
D36 Benign neoplasm of other and unspecified sites	0.128	0.872	0.000
D22.1 Melanocytic naevi of eyelid, including canthus	0.125	0.875	0.000
D22.7 Melanocytic naevi of lower limb, including hip	0.125	0.875	0.000
D10 Benign neoplasm of mouth and pharynx	0.124	0.876	0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites	0.124	0.876	0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.123	0.877	0.000
D14 Benign neoplasm of middle ear and respiratory system	0.122	0.878	0.000
D35.1 Parathyroid gland	0.121	0.879	0.000
D13.0 Oesophagus	0.120	0.880	0.000
D12.9 Anus and anal canal	0.119	0.880	0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs	0.119	0.880	0.000
D13.3 Other and unspecified parts of small intestine	0.119	0.881	0.000
D25.9 Leiomyoma of uterus, unspecified	0.119	0.881	0.000
D13.9 Ill-defined sites within the digestive system	0.117	0.883	0.000
D25.1 Intramural leiomyoma of uterus	0.117	0.883	0.000
D23.3 Skin of other and unspecified parts of face	0.116	0.884	0.000
D35.0 Adrenal gland	0.116	0.884	0.000
D13.4 Liver	0.116	0.884	0.000
D22.9 Melanocytic naevi, unspecified	0.115	0.885	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.115	0.885	0.000
D13.6 Pancreas	0.114	0.886	0.000
D33.2 Brain, unspecified	0.114	0.886	0.000
D23.4 Skin of scalp and neck	0.114	0.886	0.000
D26 Other benign neoplasms of uterus	0.113	0.886	0.000
D13.7 Endocrine pancreas	0.112	0.888	0.000
D11.0 Parotid gland	0.111	0.888	0.000
D24 Benign neoplasm of breast	0.111	0.889	0.000
D23.0 Skin of lip	0.111	0.889	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.111	0.889	0.000
D16.4 Bones of skull and face	0.110	0.890	0.000
D23.9 Skin, unspecified	0.109	0.891	0.000
D33.4 Spinal cord	0.109	0.891	0.000
D28.2 Uterine tubes and ligaments	0.109	0.891	0.000
D22.3 Melanocytic naevi of other and unspecified parts of face	0.109	0.891	0.000
D35.2 Pituitary gland	0.109	0.891	0.000
D35.9 Endocrine gland, unspecified	0.108	0.892	0.000
D35.8 Pluriglandular involvement	0.108	0.892	0.000
D35.7 Other specified endocrine glands	0.108	0.892	0.000
D35.6 Aortic body and other paraganglia	0.108	0.892	0.000
D35.5 Carotid body	0.108	0.892	0.000
D35.4 Pineal gland	0.108	0.892	0.000
D35.3 Craniopharyngeal duct	0.108	0.892	0.000
D28.0 Vulva	0.108	0.892	0.000
D33.3 Cranial nerves	0.108	0.892	0.000
D16.9 Bone and articular cartilage, unspecified	0.107	0.893	0.000
D31.0 Conjunctiva	0.106	0.894	0.000
D23.2 Skin of ear and external auricular canal	0.106	0.894	0.000
D16.3 Short bones of lower limb	0.106	0.894	0.000
D16.6 Vertebral column	0.106	0.894	0.000
D33.0 Brain, supratentorial	0.106	0.894	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.105	0.895	0.000
D16.8 Pelvic bones, sacrum and coccyx	0.105	0.895	0.000
D33.9 Central nervous system, unspecified	0.105	0.895	0.000
D33.7 Other specified parts of central nervous system	0.105	0.895	0.000
D33.1 Brain, infratentorial	0.105	0.895	0.000
D21.4 Connective and other soft tissue of abdomen	0.105	0.895	0.000
D28.7 Other specified female genital organs	0.104	0.895	0.000
D16.5 Lower jaw bone	0.104	0.895	0.000
D30.0 Kidney	0.104	0.896	0.000
D21.3 Connective and other soft tissue of thorax	0.104	0.896	0.000
D16.0 Scapula and long bones of upper limb	0.104	0.896	0.000
D22.0 Melanocytic naevi of lip	0.104	0.896	0.000
D13.2 Duodenum	0.104	0.896	0.000
D16.7 Ribs, sternum and clavicle	0.104	0.896	0.000
D21.5 Connective and other soft tissue of pelvis	0.103	0.897	0.000
D16.2 Long bones of lower limb	0.103	0.897	0.000
D15.1 Heart	0.103	0.897	0.000
D18.1 Lymphangioma, any site	0.103	0.897	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.103	0.897	0.000
D28.9 Female genital organ, unspecified	0.103	0.897	0.000
D28.1 Vagina	0.102	0.897	0.000
D16.1 Short bones of upper limb	0.102	0.897	0.000
D21.9 Connective and other soft tissue, unspecified	0.102	0.898	0.000
D11.7 Other major salivary glands	0.101	0.899	0.000
D31.4 Ciliary body	0.101	0.899	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.100	0.899	0.000
D31.6 Orbit, unspecified	0.100	0.900	0.000
D32.9 Meninges, unspecified	0.100	0.900	0.000
D30.4 Urethra	0.099	0.901	0.000
D12.0 Caecum	0.099	0.901	0.000
D31.9 Eye, unspecified	0.099	0.901	0.000
D31.5 Lachrymal gland and duct	0.099	0.901	0.000
D31.1 Cornea	0.099	0.901	0.000
D10.0 Lip	0.099	0.901	0.000
D11.9 Major salivary gland, unspecified	0.099	0.901	0.000
D34 Benign neoplasm of thyroid gland	0.099	0.901	0.000
D20.1 Peritoneum	0.098	0.902	0.000
D15.2 Mediastinum	0.098	0.902	0.000
D31.3 Choroid	0.098	0.902	0.000
D30.9 Urinary organ, unspecified	0.097	0.902	0.000
D30.7 Other urinary organs	0.097	0.902	0.000
D30.2 Ureter	0.097	0.902	0.000
D30.1 Renal pelvis	0.097	0.902	0.000
D29.0 Penis	0.097	0.903	0.000
D15.9 Intrathoracic organ, unspecified	0.097	0.903	0.000
D15.7 Other specified intrathoracic organs	0.097	0.903	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.096	0.904	0.000
D31.2 Retina	0.096	0.904	0.000
D20.0 Retroperitoneum	0.096	0.904	0.000
D23.7 Skin of lower limb, including hip	0.095	0.905	0.000
D19.9 Mesothelial tissue, unspecified	0.095	0.905	0.000
D19.7 Mesothelial tissue of other sites	0.095	0.905	0.000
D19.1 Mesothelial tissue of peritoneum	0.095	0.905	0.000
D19.0 Mesothelial tissue of pleura	0.095	0.905	0.000
D29.3 Epididymis	0.094	0.906	0.000
D32.0 Cerebral meninges	0.094	0.906	0.000
D25.0 Submucous leiomyoma of uterus	0.094	0.906	0.000
D36.9 Benign neoplasm of unspecified site	0.093	0.906	0.000
D23.5 Skin of trunk	0.093	0.907	0.000
D10.5 Other parts of oropharynx	0.093	0.907	0.000
D13.5 Extrahepatic bile ducts	0.092	0.907	0.000
D29.9 Male genital organ, unspecified	0.092	0.907	0.000
D29.7 Other male genital organs	0.092	0.907	0.000
D30.3 Bladder	0.092	0.908	0.000
D25.2 Subserosal leiomyoma of uterus	0.092	0.908	0.000
D29.1 Prostate	0.091	0.909	0.000
D15.0 Thymus	0.091	0.909	0.000
D32.1 Spinal meninges	0.090	0.910	0.000
D14.3 Bronchus and lung	0.089	0.910	0.000
D29.4 Scrotum	0.089	0.911	0.000
D10.7 Hypopharynx	0.089	0.911	0.000
D10.2 Floor of mouth	0.089	0.911	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.089	0.911	0.000
D10.9 Pharynx, unspecified	0.088	0.911	0.000
D36.7 Other specified sites	0.088	0.912	0.000
D10.4 Tonsil	0.088	0.912	0.000
D29.2 Testis	0.087	0.912	0.000
D14.4 Respiratory system, unspecified	0.087	0.912	0.000
D14.2 Trachea	0.087	0.912	0.000
D10.6 Nasopharynx	0.087	0.913	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.086	0.913	0.000
D18.0 Haemangioma, any site	0.085	0.915	0.000
D10.1 Tongue	0.085	0.915	0.000
D36.0 Lymph nodes	0.083	0.916	0.000
D14.0 Middle ear, nasal cavity and accessory sinuses	0.082	0.917	0.000
D14.1 Larynx	0.081	0.919	0.000
D26.0 Cervix uteri	0.080	0.919	0.000
D12.8 Rectum	0.080	0.920	0.000
D26.9 Uterus, unspecified	0.079	0.920	0.000
D26.7 Other parts of uterus	0.076	0.924	0.000
D26.1 Corpus uteri	0.075	0.925	0.000
D10.3 Other and unspecified parts of mouth	0.071	0.928	0.000
D23.6 Skin of upper limb, including shoulder	0.062	0.937	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.989	0.011
K76.9 Liver disease, unspecified	0.000	0.989	0.010
K76 Other diseases of liver	0.000	0.990	0.010
K76.8 Other specified diseases of liver	0.000	0.991	0.009
K76.5 Hepatic veno-occlusive disease	0.000	0.993	0.007
K76.4 Peliosis hepatis	0.000	0.993	0.007
K76.2 Central haemorrhagic necrosis of liver	0.000	0.993	0.007
K76.3 Infarction of liver	0.000	0.993	0.007
K76.7 Hepatorenal syndrome	0.000	0.993	0.007
K76.1 Chronic passive congestion of liver	0.000	0.993	0.007
K76.6 Portal hypertension	0.000	0.994	0.006
K70-K77 Diseases of liver	0.000	0.996	0.004
I44.7 Left bundle-branch block, unspecified	0.000	0.996	0.004
K42.9 Umbilical hernia without obstruction or gangrene	0.003	0.997	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.997	0.003
I44 Atrioventricular and left bundle-branch block	0.000	0.997	0.003
I44.3 Other and unspecified atrioventricular block	0.000	0.997	0.003
I44.0 Atrioventricular block, first degree	0.000	0.997	0.003
K72.9 Hepatic failure, unspecified	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
T40.2 Other opioids	0.003	0.997	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.997	0.003
K70 Alcoholic liver disease	0.000	0.997	0.003
I44.6 Other and unspecified fascicular block	0.000	0.997	0.003
T39.0 Salicylates	0.003	0.997	0.000
K71 Toxic liver disease	0.000	0.997	0.003
I44.1 Atrioventricular block, second degree	0.000	0.997	0.003
K72.1 Chronic hepatic failure	0.000	0.997	0.003
M75.4 Impingement syndrome of shoulder	0.003	0.997	0.000
K70.1 Alcoholic hepatitis	0.000	0.997	0.003
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
I44.5 Left posterior fascicular block	0.000	0.997	0.003
K72.0 Acute and subacute hepatic failure	0.000	0.997	0.003
K73 Chronic hepatitis, not elsewhere classified	0.000	0.997	0.003
I44.4 Left anterior fascicular block	0.000	0.997	0.003
K70.4 Alcoholic hepatic failure	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.002	0.997	0.000
T39.2 Pyrazolone derivatives	0.002	0.997	0.000
I44.2 Atrioventricular block, complete	0.000	0.997	0.003
K61.0 Anal abscess	0.000	0.997	0.003
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.997	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
M25.78 Osteophyte (Other)	0.000	0.997	0.003
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.002
K75 Other inflammatory liver diseases	0.000	0.998	0.002
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.998	0.002
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
K70.0 Alcoholic fatty liver	0.000	0.998	0.002
K71.9 Toxic liver disease, unspecified	0.000	0.998	0.002
Z13.9 Special screening examination, unspecified	0.002	0.998	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.998	0.002
K71.8 Toxic liver disease with other disorders of liver	0.000	0.998	0.002
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.998	0.002
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.998	0.002
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.998	0.002
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.998	0.002
K71.2 Toxic liver disease with acute hepatitis	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.000	0.998	0.002
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.998	0.002
K71.0 Toxic liver disease with cholestasis	0.000	0.998	0.002
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
K70.3 Alcoholic cirrhosis of liver	0.000	0.998	0.002
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.998	0.002
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.998	0.002
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.998	0.002
T50.9 Other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.998	0.002
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.998	0.002
T40.3 Methadone	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
T40.4 Other synthetic narcotics	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
K74.1 Hepatic sclerosis	0.000	0.998	0.002
G25.0 Essential tremor	0.000	0.998	0.002
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
K73.9 Chronic hepatitis, unspecified	0.000	0.998	0.002
K75.4 Autoimmune hepatitis	0.000	0.998	0.002
K75.9 Inflammatory liver disease, unspecified	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
M25.7 Osteophyte	0.000	0.998	0.002
T50.8 Diagnostic agents	0.002	0.998	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.998	0.002
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.998	0.002
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.998	0.002
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
L60.0 Ingrowing nail	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
K75.0 Abscess of liver	0.000	0.998	0.002
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
M25.74 Osteophyte (Hand)	0.000	0.998	0.002
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
M25.73 Osteophyte (Forearm)	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
K74.0 Hepatic fibrosis	0.000	0.998	0.002
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.998	0.002
K70.9 Alcoholic liver disease, unspecified	0.000	0.998	0.002
K74.5 Biliary cirrhosis, unspecified	0.000	0.998	0.001
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.998	0.002
O32.1 Maternal care for breech presentation	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.998	0.001
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.998	0.000
K74.3 Primary biliary cirrhosis	0.000	0.998	0.001
T41.2 Other and unspecified general anaesthetics	0.001	0.998	0.000
T48.5 Anti-common-cold drugs	0.001	0.998	0.000
T49.9 Topical agent, unspecified	0.001	0.998	0.000
T49.8 Other topical agents	0.001	0.998	0.000
T49.7 Dental drugs, topically applied	0.001	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.998	0.000
T49.2 Local astringents and local detergents	0.001	0.998	0.000
T49.1 Antipruritics	0.001	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.000	0.998	0.002
M25.70 Osteophyte (Multiple sites)	0.000	0.998	0.002
T41.5 Therapeutic gases	0.001	0.998	0.000
T41.4 Anaesthetic, unspecified	0.001	0.998	0.000
T41.3 Local anaesthetics	0.001	0.998	0.000
T41.1 Intravenous anaesthetics	0.001	0.998	0.000
T41.0 Inhaled anaesthetics	0.001	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.001	0.998	0.000
T47.4 Other laxatives	0.001	0.998	0.000
T47.2 Stimulant laxatives	0.001	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.001	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
Z33 Pregnant state, incidental	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.001	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.001	0.998	0.000
T47.7 Emetics	0.001	0.998	0.000
T47.5 Digestants	0.001	0.998	0.000
T47.3 Saline and osmotic laxatives	0.001	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.001	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.001	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.001	0.998	0.000
T44.0 Anticholinesterase agents	0.001	0.998	0.000
Z03.5 Observation for other suspected cardiovascular diseases	0.000	0.998	0.002
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.001
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.998	0.000
T42.0 Hydantoin derivatives	0.001	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.001	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.998	0.000
T45.5 Anticoagulants	0.001	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.001	0.998	0.000
T42.3 Barbiturates	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.998	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.001	0.998	0.000
I49.5 Sick sinus syndrome	0.000	0.998	0.002
T36.4 Tetracyclines	0.001	0.998	0.000
T36.3 Macrolides	0.001	0.998	0.000
T45.4 Iron and its compounds	0.001	0.998	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.998	0.000
T46.7 Peripheral vasodilators	0.001	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.001	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.998	0.000
T36.6 Rifamycins	0.001	0.998	0.000
T36.5 Aminoglycosides	0.001	0.998	0.000
T36.2 Chloramphenicol group	0.001	0.998	0.000
T42.1 Iminostilbenes	0.001	0.998	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.001	0.998	0.000
T45.2 Vitamins, not elsewhere classified	0.001	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.998	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.998	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.001	0.998	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.998	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.000	0.998	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.001	0.998	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.999	0.001
T36.8 Other systemic antibiotics	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
T46.1 Calcium-channel blockers	0.001	0.999	0.000
M25.71 Osteophyte (Shoulder region)	0.000	0.999	0.001
R87.6 Abnormal cytological findings	0.000	0.999	0.001
Z98.1 Arthrodesis status	0.001	0.999	0.000
L60 Nail disorders	0.001	0.999	0.000
T36.0 Penicillins	0.001	0.999	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.999	0.001
Y40.0 Penicillins	0.000	0.999	0.001
F31.9 Bipolar affective disorder, unspecified	0.001	0.999	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.999	0.001
J03.9 Acute tonsillitis, unspecified	0.001	0.999	0.000
L60.3 Nail dystrophy	0.001	0.999	0.000
L60.2 Onychogryphosis	0.001	0.999	0.000
R40.2 Coma, unspecified	0.001	0.999	0.000
D61 Other aplastic anaemias	0.000	0.999	0.001
I46 Cardiac arrest	0.000	0.999	0.001
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999	0.000
L60.8 Other nail disorders	0.001	0.999	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.999	0.001
L60.1 Onycholysis	0.001	0.999	0.000
Z03.1 Observation for suspected malignant neoplasm	0.001	0.999	0.000
L60.9 Nail disorder, unspecified	0.001	0.999	0.000
L60.5 Yellow nail syndrome	0.001	0.999	0.000
L60.4 Beau's lines	0.001	0.999	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
D61.1 Drug-induced aplastic anaemia	0.000	0.999	0.001
G25 Other extrapyramidal and movement disorders	0.000	0.999	0.001
Z88.0 Personal history of allergy to penicillin	0.001	0.999	0.000
D61.8 Other specified aplastic anaemias	0.000	0.999	0.001
D61.3 Idiopathic aplastic anaemia	0.000	0.999	0.001
D61.2 Aplastic anaemia due to other external agents	0.000	0.999	0.001
D61.0 Constitutional aplastic anaemia	0.000	0.999	0.001
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.999	0.001
M81.9 Osteoporosis, unspecified	0.000	0.999	0.001
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.001	0.999	0.000
K42 Umbilical hernia	0.001	0.999	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.999	0.001
I46.1 Sudden cardiac death, so described	0.000	0.999	0.001
K61.1 Rectal abscess	0.000	0.999	0.001
M19.9 Arthrosis, unspecified	0.000	0.999	0.001
K61 Abscess of anal and rectal regions	0.000	0.999	0.001
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.999	0.001
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.999	0.001
G25.5 Other chorea	0.000	0.999	0.001
R40.0 Somnolence	0.001	0.999	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.999	0.001
M81.98 Osteoporosis, unspecified (Other)	0.000	0.999	0.001
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.999	0.001
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.999	0.001
G25.4 Drug-induced chorea	0.000	0.999	0.001
K61.4 Intrasphincteric abscess	0.000	0.999	0.001
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.999	0.001
G25.2 Other specified forms of tremor	0.000	0.999	0.001
K56.2 Volvulus	0.001	0.999	0.000
S29.9 Unspecified injury of thorax	0.000	0.999	0.001
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.000	0.999	0.001
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.999	0.001
G25.1 Drug-induced tremor	0.000	0.999	0.001
T43.2 Other and unspecified antidepressants	0.001	0.999	0.000
Y40.8 Other systemic antibiotics	0.000	0.999	0.001
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.999	0.001
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.999	0.001
K42.1 Umbilical hernia with gangrene	0.001	0.999	0.000
K61.2 Anorectal abscess	0.000	0.999	0.001
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.999	0.001
C54.1 Endometrium	0.000	0.999	0.001
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.999	0.001
G25.3 Myoclonus	0.000	0.999	0.001
I49.4 Other and unspecified premature depolarisation	0.000	0.999	0.001
K61.3 Ischiorectal abscess	0.000	0.999	0.001
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.999	0.001
H02.0 Entropion and trichiasis of eyelid	0.000	0.999	0.001
Y40.3 Macrolides	0.000	0.999	0.001
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations