TreeWAS – Variant ID: rs2572207

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y86 Sequelae of other accidents	0.051	0.949	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.018	0.982	0.000
O72.0 Third-stage haemorrhage	0.015	0.985	0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.015	0.985	0.000
Y89 Sequelae of other external causes	0.015	0.985	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.986	0.014
Y87.1 Sequelae of assault	0.012	0.988	0.000
Y89.9 Sequelae of unspecified external cause	0.012	0.988	0.000
Y88 Sequelae of surgical and medical care as external cause	0.012	0.988	0.000
M81.9 Osteoporosis, unspecified	0.012	0.988	0.000
Q76 Congenital malformations of spine and bony thorax	0.012	0.988	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.011	0.989	0.000
Y87.0 Sequelae of intentional self-harm	0.011	0.989	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.011	0.989	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.011	0.989	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.011	0.989	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.011	0.989	0.000
Y89.1 Sequelae of war operations	0.011	0.989	0.000
Y89.0 Sequelae of legal intervention	0.011	0.989	0.000
Q76.0 Spina bifida occulta	0.011	0.989	0.000
Y87.2 Sequelae of events of undetermined intent	0.010	0.989	0.000
O72 Postpartum haemorrhage	0.010	0.990	0.000
Q67.5 Congenital deformity of spine	0.010	0.990	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.010	0.990	0.000
M81.98 Osteoporosis, unspecified (Other)	0.010	0.990	0.000
Y85 Sequelae of transport accidents	0.010	0.990	0.000
Q66 Congenital deformities of feet	0.010	0.990	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.009	0.991	0.000
M81 Osteoporosis without pathological fracture	0.009	0.991	0.000
Q79.6 Ehlers-Danlos syndrome	0.009	0.991	0.000
Q67.6 Pectus excavatum	0.009	0.991	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.009	0.991	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.991	0.009
M81.93 Osteoporosis, unspecified (Forearm)	0.009	0.991	0.000
Q66.0 Talipes equinovarus	0.009	0.991	0.000
Q76.1 Klippel-Feil syndrome	0.009	0.991	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.008	0.991	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.008	0.991	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.008	0.991	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.008	0.991	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.008	0.991	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.008	0.991	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.008	0.991	0.000
Q76.8 Other congenital malformations of bony thorax	0.008	0.991	0.000
Q76.7 Congenital malformation of sternum	0.008	0.991	0.000
Q76.6 Other congenital malformations of ribs	0.008	0.991	0.000
Q76.5 Cervical rib	0.008	0.991	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.008	0.991	0.000
Q76.2 Congenital spondylolisthesis	0.008	0.991	0.000
D26.1 Corpus uteri	0.009	0.991	0.000
M81.4 Drug-induced osteoporosis	0.008	0.991	0.000
Q66.7 Pes cavus	0.008	0.992	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.008	0.992	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.008	0.992	0.000
Q75 Other congenital malformations of skull and face bones	0.008	0.992	0.000
Q73 Reduction defects of unspecified limb	0.008	0.992	0.000
Q72 Reduction defects of lower limb	0.008	0.992	0.000
Q71 Reduction defects of upper limb	0.008	0.992	0.000
Q70 Syndactyly	0.008	0.992	0.000
Q69 Polydactyly	0.008	0.992	0.000
Q68 Other congenital musculoskeletal deformities	0.008	0.992	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.008	0.992	0.000
O72.1 Other immediate postpartum haemorrhage	0.008	0.992	0.000
Q67.8 Other congenital deformities of chest	0.008	0.992	0.000
Q67.7 Pectus carinatum	0.008	0.992	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.008	0.992	0.000
Q67.3 Plagiocephaly	0.008	0.992	0.000
Q67.2 Dolichocephaly	0.008	0.992	0.000
Q67.1 Compression facies	0.008	0.992	0.000
Q67.0 Facial asymmetry	0.008	0.992	0.000
Q66.6 Other congenital valgus deformities of feet	0.008	0.992	0.000
N30.8 Other cystitis	0.000	0.992	0.008
Q78 Other osteochondrodysplasias	0.008	0.992	0.000
Q74 Other congenital malformations of limb(s)	0.008	0.992	0.000
O72.3 Postpartum coagulation defects	0.008	0.992	0.000
Q66.9 Congenital deformity of feet, unspecified	0.008	0.992	0.000
Q65 Congenital deformities of hip	0.007	0.992	0.000
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.007	0.992	0.000
Q79.5 Other congenital malformations of abdominal wall	0.007	0.992	0.000
Q79.4 Prune belly syndrome	0.007	0.992	0.000
Q79.3 Gastroschisis	0.007	0.992	0.000
Q79.2 Exomphalos	0.007	0.992	0.000
Q79.1 Other congenital malformations of diaphragm	0.007	0.992	0.000
Q79.0 Congenital diaphragmatic hernia	0.007	0.992	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.992	0.008
M81.49 Drug-induced osteoporosis (Site unspecified)	0.007	0.993	0.000
Q66.5 Congenital pes planus	0.007	0.993	0.000
Q66.4 Talipes calcaneovalgus	0.007	0.993	0.000
Q66.1 Talipes calcaneovarus	0.007	0.993	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.007	0.993	0.000
N99.0 Postprocedural renal failure	0.000	0.993	0.007
N30.1 Interstitial cystitis (chronic)	0.000	0.993	0.007
Y85.9 Sequelae of other and unspecified transport accidents	0.007	0.993	0.000
O02.1 Missed abortion	0.007	0.993	0.000
Q66.3 Other congenital varus deformities of feet	0.007	0.993	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.993	0.007
M81.8 Other osteoporosis	0.007	0.993	0.000
M81.6 Localised osteoporosis [Lequesne]	0.007	0.993	0.000
M81.5 Idiopathic osteoporosis	0.007	0.993	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.007	0.993	0.000
M81.1 Postoophorectomy osteoporosis	0.007	0.993	0.000
N18.3 Chronic kidney disease, stage 3	0.000	0.993	0.007
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.007	0.993	0.000
M81.2 Osteoporosis of disuse	0.007	0.993	0.000
Q66.2 Metatarsus varus	0.007	0.993	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.993	0.007
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.993	0.007
I84.1 Internal haemorrhoids with other complications	0.000	0.993	0.007
Z13.1 Special screening examination for diabetes mellitus	0.007	0.993	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.993	0.007
M81.0 Postmenopausal osteoporosis	0.006	0.993	0.000
M80-M85 Disorders of bone density and structure	0.006	0.994	0.000
M81.48 Drug-induced osteoporosis (Other)	0.006	0.994	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.006	0.994	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.006	0.994	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.006	0.994	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.006	0.994	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.006	0.994	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.006	0.994	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.006	0.994	0.000
K41 Femoral hernia	0.000	0.994	0.006
Q68.8 Other specified congenital musculoskeletal deformities	0.006	0.994	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.006	0.994	0.000
Q68.4 Congenital bowing of tibia and fibula	0.006	0.994	0.000
Q68.3 Congenital bowing of femur	0.006	0.994	0.000
Q68.2 Congenital deformity of knee	0.006	0.994	0.000
Q68.1 Congenital deformity of hand	0.006	0.994	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.006	0.994	0.000
Q69.9 Polydactyly, unspecified	0.006	0.994	0.000
Q69.2 Accessory toe(s)	0.006	0.994	0.000
Q69.1 Accessory thumb(s)	0.006	0.994	0.000
Q69.0 Accessory finger(s)	0.006	0.994	0.000
Q70.9 Syndactyly, unspecified	0.006	0.994	0.000
Q70.4 Polysyndactyly	0.006	0.994	0.000
Q70.3 Webbed toes	0.006	0.994	0.000
Q70.2 Fused toes	0.006	0.994	0.000
Q70.1 Webbed fingers	0.006	0.994	0.000
Q70.0 Fused fingers	0.006	0.994	0.000
Q71.9 Reduction defect of upper limb, unspecified	0.006	0.994	0.000
Q71.8 Other reduction defects of upper limb(s)	0.006	0.994	0.000
Q71.6 Lobster-claw hand	0.006	0.994	0.000
Q71.5 Longitudinal reduction defect of ulna	0.006	0.994	0.000
Q71.4 Longitudinal reduction defect of radius	0.006	0.994	0.000
Q71.3 Congenital absence of hand and finger(s)	0.006	0.994	0.000
Q71.2 Congenital absence of both forearm and hand	0.006	0.994	0.000
Q71.1 Congenital absence of upper arm and forearm with hand present	0.006	0.994	0.000
Q71.0 Congenital complete absence of upper limb(s)	0.006	0.994	0.000
Q72.9 Reduction defect of lower limb, unspecified	0.006	0.994	0.000
Q72.8 Other reduction defects of lower limb(s)	0.006	0.994	0.000
Q72.7 Split foot	0.006	0.994	0.000
Q72.6 Longitudinal reduction defect of fibula	0.006	0.994	0.000
Q72.5 Longitudinal reduction defect of tibia	0.006	0.994	0.000
Q72.4 Longitudinal reduction defect of femur	0.006	0.994	0.000
Q72.3 Congenital absence of foot and toe(s)	0.006	0.994	0.000
Q72.2 Congenital absence of both lower leg and foot	0.006	0.994	0.000
Q72.1 Congenital absence of thigh and lower leg with foot present	0.006	0.994	0.000
Q72.0 Congenital complete absence of lower limb(s)	0.006	0.994	0.000
Q73.8 Other reduction defects of unspecified limb(s)	0.006	0.994	0.000
Q73.1 Phocomelia, unspecified limb(s)	0.006	0.994	0.000
Q73.0 Congenital absence of unspecified limb(s)	0.006	0.994	0.000
Q75.9 Congenital malformation of skull and face bones, unspecified	0.006	0.994	0.000
Q75.8 Other specified congenital malformations of skull and face bones	0.006	0.994	0.000
Q75.5 Oculomandibular dysostosis	0.006	0.994	0.000
Q75.4 Mandibulofacial dysostosis	0.006	0.994	0.000
Q75.3 Macrocephaly	0.006	0.994	0.000
Q75.2 Hypertelorism	0.006	0.994	0.000
Q75.1 Craniofacial dysostosis	0.006	0.994	0.000
Q75.0 Craniosynostosis	0.006	0.994	0.000
Q77.9 Osteochondrodysplasia with defects of growth of tubular bones and spine, unspecified	0.006	0.994	0.000
Q77.8 Other osteochondrodysplasia with defects of growth of tubular bones and spine	0.006	0.994	0.000
Q77.7 Spondyloepiphyseal dysplasia	0.006	0.994	0.000
Q77.6 Chondroectodermal dysplasia	0.006	0.994	0.000
Q77.5 Diastrophic dysplasia	0.006	0.994	0.000
Q77.4 Achondroplasia	0.006	0.994	0.000
Q77.3 Chondrodysplasia punctata	0.006	0.994	0.000
Q77.2 Short rib syndrome	0.006	0.994	0.000
Q77.1 Thanatophoric short stature	0.006	0.994	0.000
Q77.0 Achondrogenesis	0.006	0.994	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.994	0.006
Q65.2 Congenital dislocation of hip, unspecified	0.006	0.994	0.000
M84 Disorders of continuity of bone	0.006	0.994	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.006	0.994	0.000
Q78.8 Other specified osteochondrodysplasias	0.006	0.994	0.000
Q78.6 Multiple congenital exostoses	0.006	0.994	0.000
Q78.5 Metaphyseal dysplasia	0.006	0.994	0.000
Q78.4 Enchondromatosis	0.006	0.994	0.000
Q78.3 Progressive diaphyseal dysplasia	0.006	0.994	0.000
Q78.2 Osteopetrosis	0.006	0.994	0.000
Q78.1 Polyostotic fibrous dysplasia	0.006	0.994	0.000
N99.5 Malfunction of external stoma of urinary tract	0.000	0.994	0.006
Q74.9 Unspecified congenital malformation of limb(s)	0.006	0.994	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.006	0.994	0.000
Q74.3 Arthrogryposis multiplex congenita	0.006	0.994	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.006	0.994	0.000
N99.1 Postprocedural urethral stricture	0.000	0.994	0.006
M84.4 Pathological fracture, not elsewhere classified	0.006	0.994	0.000
Q66.8 Other congenital deformities of feet	0.006	0.994	0.000
M82 Osteoporosis in diseases classified elsewhere	0.006	0.994	0.000
Q65.9 Congenital deformity of hip, unspecified	0.006	0.994	0.000
Q65.6 Unstable hip	0.006	0.994	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.006	0.994	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.006	0.994	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.006	0.994	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.006	0.994	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.006	0.994	0.000
Q74.1 Congenital malformation of knee	0.005	0.994	0.000
T93.1 Sequelae of fracture of femur	0.006	0.994	0.000
Q78.0 Osteogenesis imperfecta	0.005	0.994	0.000
T93 Sequelae of injuries of lower limb	0.006	0.994	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.005	0.994	0.000
T93.2 Sequelae of other fractures of lower limb	0.006	0.994	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.005	0.994	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.005	0.995	0.000
M84.2 Delayed union of fracture	0.005	0.995	0.000
N30 Cystitis	0.000	0.995	0.005
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.005	0.995	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.005	0.995	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.005	0.995	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.005	0.995	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.005	0.995	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.005	0.995	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.005	0.995	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.005	0.995	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.005	0.995	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.005	0.995	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.58 Idiopathic osteoporosis (Other)	0.005	0.995	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.005	0.995	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.005	0.995	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.005	0.995	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.005	0.995	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.005	0.995	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.005	0.995	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.005	0.995	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.005	0.995	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.005	0.995	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.005	0.995	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.005	0.995	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.005	0.995	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.005	0.995	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.005	0.995	0.000
M81.89 Other osteoporosis (Site unspecified)	0.005	0.995	0.000
M81.88 Other osteoporosis (Other)	0.005	0.995	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.86 Other osteoporosis (Lower leg)	0.005	0.995	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.84 Other osteoporosis (Hand)	0.005	0.995	0.000
M81.83 Other osteoporosis (Forearm)	0.005	0.995	0.000
M81.82 Other osteoporosis (Upper arm)	0.005	0.995	0.000
M81.81 Other osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.80 Other osteoporosis (Multiple sites)	0.005	0.995	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.005	0.995	0.000
M82.1 Osteoporosis in endocrine disorders	0.005	0.995	0.000
N30.3 Trigonitis	0.000	0.995	0.005
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.005	0.995	0.000
M81.28 Osteoporosis of disuse (Other)	0.005	0.995	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.005	0.995	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.005	0.995	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.005	0.995	0.000
M81.24 Osteoporosis of disuse (Hand)	0.005	0.995	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.005	0.995	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.005	0.995	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.005	0.995	0.000
M84.26 Delayed union of fracture (Lower leg)	0.005	0.995	0.000
L81.9 Disorder of pigmentation, unspecified	0.005	0.995	0.000
M80 Osteoporosis with pathological fracture	0.005	0.995	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.005	0.995	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.005	0.995	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.005	0.995	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.005	0.995	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.005	0.995	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.005	0.995	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.005	0.995	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.005	0.995	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.005	0.995	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.005	0.995	0.000
M84.3 Stress fracture, not elsewhere classified	0.005	0.995	0.000
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.995	0.005
M83 Adult osteomalacia	0.005	0.995	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.995	0.005
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.995	0.005
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.995	0.005
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.995	0.005
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.995	0.005
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.005	0.995	0.000
M79.69 Pain in limb (Site unspecified)	0.000	0.995	0.005
M84.8 Other disorders of continuity of bone	0.005	0.995	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.005	0.995	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.005	0.995	0.000
N30.4 Irradiation cystitis	0.000	0.995	0.005
Q65.8 Other congenital deformities of hip	0.004	0.995	0.000
M84.9 Disorder of continuity of bone, unspecified	0.004	0.995	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.004	0.995	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.004	0.996	0.000
I12 Hypertensive renal disease	0.000	0.996	0.004
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.004	0.996	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.004	0.996	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.004	0.996	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.004	0.996	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.996	0.004
O02 Other abnormal products of conception	0.004	0.996	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.996	0.004
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.004	0.996	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.004	0.996	0.000
C34.1 Upper lobe, bronchus or lung	0.004	0.996	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.004	0.996	0.000
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.004	0.996	0.000
M84.28 Delayed union of fracture (Other)	0.004	0.996	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.004	0.996	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.004	0.996	0.000
M84.24 Delayed union of fracture (Hand)	0.004	0.996	0.000
M84.23 Delayed union of fracture (Forearm)	0.004	0.996	0.000
M84.22 Delayed union of fracture (Upper arm)	0.004	0.996	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.004	0.996	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.004	0.996	0.000
M85 Other disorders of bone density and structure	0.004	0.996	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.004	0.996	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.996	0.004
Q50.4 Embryonic cyst of Fallopian tube	0.004	0.996	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.004	0.996	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.004	0.996	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.004	0.996	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.004	0.996	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.004	0.996	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.004	0.996	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.004	0.996	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.004	0.996	0.000
M88.9 Paget's disease of bone, unspecified	0.000	0.996	0.004
G93.4 Encephalopathy, unspecified	0.004	0.996	0.000
Y85.0 Sequelae of motor-vehicle accident	0.004	0.996	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.004	0.996	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.004	0.996	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.004	0.996	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.004	0.996	0.000
O02.9 Abnormal product of conception, unspecified	0.004	0.996	0.000
L81.4 Other melanin hyperpigmentation	0.004	0.996	0.000
T93.0 Sequelae of open wound of lower limb	0.004	0.996	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.004	0.996	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.004	0.996	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.004	0.996	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M83.8 Other adult osteomalacia	0.004	0.996	0.000
M83.9 Adult osteomalacia, unspecified	0.004	0.996	0.000
M83.5 Other drug-induced osteomalacia in adults	0.004	0.996	0.000
M83.4 Aluminum bone disease	0.004	0.996	0.000
M83.3 Adult osteomalacia due to malnutrition	0.004	0.996	0.000
M83.2 Adult osteomalacia due to malabsorption	0.004	0.996	0.000
M83.0 Puerperal osteomalacia	0.004	0.996	0.000
M80.8 Other osteoporosis with pathological fracture	0.004	0.996	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.004	0.996	0.000
M83.1 Senile osteomalacia	0.003	0.996	0.000
M84.0 Malunion of fracture	0.004	0.996	0.000
Z33 Pregnant state, incidental	0.000	0.996	0.004
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.003	0.996	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.003	0.996	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.003	0.996	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.003	0.996	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.996	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.003	0.996	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.003	0.996	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.003	0.996	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.003	0.996	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.004	0.996	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.003	0.996	0.000
M84.88 Other disorders of continuity of bone (Other)	0.003	0.996	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.003	0.996	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.003	0.996	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.003	0.996	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.003	0.996	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.003	0.996	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.003	0.996	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.004	0.996	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.003	0.996	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.996	0.004
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.003	0.996	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.003	0.996	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.003	0.996	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.003	0.996	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.003	0.996	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.003	0.996	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.003	0.996	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.003	0.996	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.003	0.996	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.003	0.996	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.996	0.003
L81 Other disorders of pigmentation	0.004	0.996	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.003	0.997	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.003	0.997	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.003	0.997	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.003	0.997	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.003	0.997	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.003	0.997	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.003	0.997	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.003	0.997	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.003	0.997	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.003	0.997	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.003	0.997	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.003	0.997	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.003	0.997	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.003	0.997	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.003	0.997	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.003	0.997	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.003	0.997	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.003	0.997	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.003	0.997	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.003	0.997	0.000
O02.8 Other specified abnormal products of conception	0.003	0.997	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.997	0.003
Q50-Q56 Congenital malformations of genital organs	0.003	0.997	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.003	0.997	0.000
M84.02 Malunion of fracture (Upper arm)	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.003	0.997	0.000
N99-N99 Other disorders of the genitourinary system	0.000	0.997	0.003
D73.0 Hyposplenism	0.000	0.997	0.003
H43.1 Vitreous haemorrhage	0.000	0.997	0.003
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.003	0.997	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.997	0.003
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.000	0.997	0.003
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M88.94 Paget's disease of bone, unspecified (Hand)	0.000	0.997	0.003
M88.93 Paget's disease of bone, unspecified (Forearm)	0.000	0.997	0.003
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.000	0.997	0.003
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.000	0.997	0.003
T93.9 Sequelae of unspecified injury of lower limb	0.003	0.997	0.000
Q54 Hypospadias	0.003	0.997	0.000
L81.2 Freckles	0.003	0.997	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.997	0.003
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.003	0.997	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.003	0.997	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.003	0.997	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.003	0.997	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations