TreeWAS – Variant ID: rs2596230

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50 Crohn's disease [regional enteritis]	0.000	0.952	0.048
K50.9 Crohn's disease, unspecified	0.000	0.952	0.048
K50.0 Crohn's disease of small intestine	0.000	0.955	0.045
K50.1 Crohn's disease of large intestine	0.000	0.958	0.042
K51 Ulcerative colitis	0.000	0.959	0.041
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances	0.000	0.960	0.040
K51.2 Ulcerative (chronic) proctitis	0.000	0.961	0.039
K50-K52 Noninfective enteritis and colitis	0.000	0.962	0.038
K50.8 Other Crohn's disease	0.000	0.962	0.037
K51.4 Pseudopolyposis of colon	0.000	0.963	0.037
K51.5 Mucosal proctocolitis	0.000	0.964	0.036
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.968	0.032
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.969	0.031
K65.0 Acute peritonitis	0.031	0.969	0.000
K51.8 Other ulcerative colitis	0.000	0.973	0.027
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.973	0.027
I50.9 Heart failure, unspecified	0.021	0.979	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.980	0.020
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.000	0.986	0.014
M79.09 Rheumatism, unspecified (Site unspecified)	0.013	0.987	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.988	0.012
M79.0 Rheumatism, unspecified	0.012	0.988	0.000
Z88.2 Personal history of allergy to sulphonamides	0.000	0.988	0.012
M79.8 Other specified soft tissue disorders	0.012	0.988	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.011	0.989	0.000
M79.82 Other specified soft tissue disorders (Upper arm)	0.011	0.989	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.011	0.989	0.000
Z88.1 Personal history of allergy to other antibiotic agents	0.000	0.989	0.011
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.989	0.011
M79.10 Myalgia (Multiple sites)	0.010	0.989	0.000
M79.1 Myalgia	0.010	0.990	0.000
Z88.5 Personal history of allergy to narcotic agent	0.000	0.990	0.010
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.010	0.990	0.000
M79.80 Other specified soft tissue disorders (Multiple sites)	0.010	0.990	0.000
M67.8 Other specified disorders of synovium and tendon	0.010	0.990	0.000
M79.5 Residual foreign body in soft tissue	0.010	0.990	0.000
Z88.7 Personal history of allergy to serum and vaccine	0.000	0.990	0.010
M79.08 Rheumatism, unspecified (Other)	0.010	0.990	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.010	0.990	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.009	0.991	0.000
M79.54 Residual foreign body in soft tissue (Hand)	0.009	0.991	0.000
M79.07 Rheumatism, unspecified (Ankle and foot)	0.009	0.991	0.000
M79.06 Rheumatism, unspecified (Lower leg)	0.009	0.991	0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
M79.04 Rheumatism, unspecified (Hand)	0.009	0.991	0.000
M79.03 Rheumatism, unspecified (Forearm)	0.009	0.991	0.000
M79.02 Rheumatism, unspecified (Upper arm)	0.009	0.991	0.000
M79.01 Rheumatism, unspecified (Shoulder region)	0.009	0.991	0.000
M79.00 Rheumatism, unspecified (Multiple sites)	0.009	0.991	0.000
M79.7 Fibromyalgia	0.009	0.991	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.009	0.991	0.000
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.991	0.009
M79.9 Soft tissue disorder, unspecified	0.008	0.992	0.000
M79.56 Residual foreign body in soft tissue (Lower leg)	0.008	0.992	0.000
M79.3 Panniculitis, unspecified	0.008	0.992	0.000
K65 Peritonitis	0.008	0.992	0.000
M79.79 Fibromyalgia (Site unspecified)	0.008	0.992	0.000
M79.18 Myalgia (Other)	0.008	0.992	0.000
M79.4 Hypertrophy of (infrapatellar) fat pad	0.008	0.992	0.000
N89.8 Other specified noninflammatory disorders of vagina	0.000	0.992	0.008
M79.57 Residual foreign body in soft tissue (Ankle and foot)	0.008	0.992	0.000
M79.88 Other specified soft tissue disorders (Other)	0.008	0.992	0.000
M79.17 Myalgia (Ankle and foot)	0.008	0.992	0.000
M79.14 Myalgia (Hand)	0.008	0.992	0.000
M79.13 Myalgia (Forearm)	0.008	0.992	0.000
M79.12 Myalgia (Upper arm)	0.008	0.992	0.000
M79.11 Myalgia (Shoulder region)	0.008	0.992	0.000
M79.15 Myalgia (Pelvic region and thigh)	0.007	0.992	0.000
M79.59 Residual foreign body in soft tissue (Site unspecified)	0.007	0.992	0.000
M79.58 Residual foreign body in soft tissue (Other)	0.007	0.992	0.000
M79.55 Residual foreign body in soft tissue (Pelvic region and thigh)	0.007	0.992	0.000
M79.53 Residual foreign body in soft tissue (Forearm)	0.007	0.992	0.000
M79.52 Residual foreign body in soft tissue (Upper arm)	0.007	0.992	0.000
M79.51 Residual foreign body in soft tissue (Shoulder region)	0.007	0.992	0.000
M79.50 Residual foreign body in soft tissue (Multiple sites)	0.007	0.992	0.000
M79.16 Myalgia (Lower leg)	0.007	0.992	0.000
M79.19 Myalgia (Site unspecified)	0.007	0.993	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.993	0.007
I27.2 Other secondary pulmonary hypertension	0.000	0.993	0.007
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.006	0.993	0.000
M79.78 Fibromyalgia (Other)	0.006	0.993	0.000
M79.77 Fibromyalgia (Ankle and foot)	0.006	0.993	0.000
M79.76 Fibromyalgia (Lower leg)	0.006	0.993	0.000
M79.75 Fibromyalgia (Pelvic region and thigh)	0.006	0.993	0.000
M79.74 Fibromyalgia (Hand)	0.006	0.993	0.000
M79.73 Fibromyalgia (Forearm)	0.006	0.993	0.000
M79.72 Fibromyalgia (Upper arm)	0.006	0.993	0.000
M79.71 Fibromyalgia (Shoulder region)	0.006	0.993	0.000
M79.99 Soft tissue disorder, unspecified (Site unspecified)	0.006	0.994	0.000
M79.98 Soft tissue disorder, unspecified (Other)	0.006	0.994	0.000
M79.97 Soft tissue disorder, unspecified (Ankle and foot)	0.006	0.994	0.000
M79.95 Soft tissue disorder, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M79.94 Soft tissue disorder, unspecified (Hand)	0.006	0.994	0.000
M79.93 Soft tissue disorder, unspecified (Forearm)	0.006	0.994	0.000
M79.92 Soft tissue disorder, unspecified (Upper arm)	0.006	0.994	0.000
M79.91 Soft tissue disorder, unspecified (Shoulder region)	0.006	0.994	0.000
M79.90 Soft tissue disorder, unspecified (Multiple sites)	0.006	0.994	0.000
M79.39 Panniculitis, unspecified (Site unspecified)	0.006	0.994	0.000
M79.38 Panniculitis, unspecified (Other)	0.006	0.994	0.000
M79.37 Panniculitis, unspecified (Ankle and foot)	0.006	0.994	0.000
M79.36 Panniculitis, unspecified (Lower leg)	0.006	0.994	0.000
M79.35 Panniculitis, unspecified (Pelvic region and thigh)	0.006	0.994	0.000
M79.34 Panniculitis, unspecified (Hand)	0.006	0.994	0.000
M79.33 Panniculitis, unspecified (Forearm)	0.006	0.994	0.000
M79.32 Panniculitis, unspecified (Upper arm)	0.006	0.994	0.000
M79.31 Panniculitis, unspecified (Shoulder region)	0.006	0.994	0.000
M79.30 Panniculitis, unspecified (Multiple sites)	0.006	0.994	0.000
M79.49 Hypertrophy of (infrapatellar) fat pad-Site unspec	0.006	0.994	0.000
M79.48 Hypertrophy of (infrapatellar) fat pad (Other)	0.006	0.994	0.000
M79.47 Hypertrophy of (infrapatellar) fat pad (Ankle and foot)	0.006	0.994	0.000
M79.45 Hypertrophy of (infrapatellar) fat pad (Pelvic region and thigh)	0.006	0.994	0.000
M79.44 Hypertrophy of (infrapatellar) fat pad (Hand)	0.006	0.994	0.000
M79.43 Hypertrophy of (infrapatellar) fat pad (Forearm)	0.006	0.994	0.000
M79.42 Hypertrophy of (infrapatellar) fat pad (Upper arm)	0.006	0.994	0.000
M79.41 Hypertrophy of (infrapatellar) fat pad (Shoulder region)	0.006	0.994	0.000
M79.40 Hypertrophy of (infrapatellar) fat pad (Multiple sites)	0.006	0.994	0.000
K52.1 Toxic gastro-enteritis and colitis	0.000	0.994	0.006
M79.46 Hypertrophy of (infrapatellar) fat pad (Lower leg)	0.006	0.994	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.995	0.005
S83.2 Tear of meniscus, current	0.000	0.995	0.005
M67 Other disorders of synovium and tendon	0.005	0.995	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.005	0.995	0.000
M79.2 Neuralgia and neuritis, unspecified	0.005	0.995	0.000
M79.70 Fibromyalgia (Multiple sites)	0.005	0.995	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.995	0.005
J31.0 Chronic rhinitis	0.000	0.995	0.005
K65.9 Peritonitis, unspecified	0.005	0.995	0.000
Z88.6 Personal history of allergy to analgesic agent	0.000	0.995	0.005
R52.1 Chronic intractable pain	0.005	0.995	0.000
K52.3 Indeterminate colitis	0.000	0.995	0.004
K65.8 Other peritonitis	0.004	0.995	0.000
M67.0 Short Achilles tendon (acquired)	0.004	0.995	0.000
M67.1 Other contracture of tendon (sheath)	0.004	0.996	0.000
Z34.8 Supervision of other normal pregnancy	0.000	0.996	0.004
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.996	0.004
I50 Heart failure	0.004	0.996	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.004	0.996	0.000
M67.4 Ganglion	0.004	0.996	0.000
M67.3 Transient synovitis	0.004	0.996	0.000
M79.27 Neuralgia and neuritis, unspecified (Ankle and foot)	0.004	0.996	0.000
M79.24 Neuralgia and neuritis, unspecified (Hand)	0.004	0.996	0.000
M79.23 Neuralgia and neuritis, unspecified (Forearm)	0.004	0.996	0.000
M79.22 Neuralgia and neuritis, unspecified (Upper arm)	0.004	0.996	0.000
M79.21 Neuralgia and neuritis, unspecified (Shoulder region)	0.004	0.996	0.000
M79.20 Neuralgia and neuritis, unspecified (Multiple sites)	0.004	0.996	0.000
C83.3 Large cell (diffuse)	0.004	0.996	0.000
R74.8 Abnormal levels of other serum enzymes	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.004	0.996	0.000
Z88.0 Personal history of allergy to penicillin	0.000	0.996	0.004
I05.9 Mitral valve disease, unspecified	0.004	0.996	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.004	0.996	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.003	0.996	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.996	0.004
N89 Other noninflammatory disorders of vagina	0.000	0.996	0.004
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.003	0.996	0.000
I05.0 Mitral stenosis	0.004	0.996	0.000
Q38.7 Pharyngeal pouch	0.004	0.996	0.000
C44.6 Skin of upper limb, including shoulder	0.004	0.996	0.000
K63.8 Other specified diseases of intestine	0.000	0.996	0.004
I05 Rheumatic mitral valve diseases	0.004	0.996	0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.003	0.996	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.996	0.004
I27 Other pulmonary heart diseases	0.000	0.996	0.003
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.997	0.003
M79.28 Neuralgia and neuritis, unspecified (Other)	0.003	0.997	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.997	0.003
C78.1 Secondary malignant neoplasm of mediastinum	0.003	0.997	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.003	0.997	0.000
Q24 Other congenital malformations of heart	0.003	0.997	0.000
M67.49 Ganglion, multiple sites	0.003	0.997	0.000
M67.47 Ganglion, ankle and foot	0.003	0.997	0.000
M67.45 Ganglion, hip	0.003	0.997	0.000
M67.43 Ganglion, wrist	0.003	0.997	0.000
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.003	0.997	0.000
K92.0 Haematemesis	0.003	0.997	0.000
I50.1 Left ventricular failure	0.003	0.997	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
Q24.5 Malformation of coronary vessels	0.003	0.997	0.000
I05.2 Mitral stenosis with insufficiency	0.003	0.997	0.000
N89.6 Tight hymenal ring	0.000	0.997	0.003
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.003	0.997	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.003	0.997	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.003	0.997	0.000
N89.9 Noninflammatory disorder of vagina, unspecified	0.000	0.997	0.003
Q27 Other congenital malformations of peripheral vascular system	0.003	0.997	0.000
Q27.3 Peripheral arteriovenous malformation	0.003	0.997	0.000
I05.1 Rheumatic mitral insufficiency	0.003	0.997	0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.003	0.997	0.000
M50.3 Other cervical disk degeneration	0.003	0.997	0.000
N89.7 Haematocolpos	0.000	0.997	0.003
N89.4 Leukoplakia of vagina	0.000	0.997	0.003
N89.3 Dysplasia of vagina, unspecified	0.000	0.997	0.003
N89.2 Severe vaginal dysplasia, not elsewhere classified	0.000	0.997	0.003
N89.1 Moderate vaginal dysplasia	0.000	0.997	0.003
N89.0 Mild vaginal dysplasia	0.000	0.997	0.003
Q24.0 Dextrocardia	0.003	0.997	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.003	0.997	0.000
I05.8 Other mitral valve diseases	0.003	0.997	0.000
C83.1 Small cleaved cell (diffuse)	0.003	0.997	0.000
M50.1 Cervical disk disorder with radiculopathy	0.003	0.997	0.000
Q23 Congenital malformations of aortic and mitral valves	0.003	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.000	0.997	0.003
Q24.8 Other specified congenital malformations of heart	0.003	0.997	0.000
M50 Cervical disk disorders	0.003	0.997	0.000
Q28 Other congenital malformations of circulatory system	0.003	0.997	0.000
N89.5 Stricture and atresia of vagina	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.000	0.997	0.003
C83.7 Burkitt's tumour	0.003	0.997	0.000
C83.6 Undifferentiated (diffuse)	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.003	0.997	0.000
C83.4 Immunoblastic (diffuse)	0.003	0.997	0.000
C83.2 Mixed small and large cell (diffuse)	0.003	0.997	0.000
D68.5 Primary Thrombophilia	0.003	0.997	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.997	0.003
Z34 Supervision of normal pregnancy	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
D68 Other coagulation defects	0.003	0.997	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.003	0.997	0.000
Q24.6 Congenital heart block	0.002	0.997	0.000
Q24.4 Congenital subaortic stenosis	0.002	0.997	0.000
Q24.3 Pulmonary infundibular stenosis	0.002	0.997	0.000
Q24.2 Cor triatriatum	0.002	0.997	0.000
Q24.1 Levocardia	0.002	0.997	0.000
J42 Unspecified chronic bronchitis	0.003	0.997	0.000
D68.9 Coagulation defect, unspecified	0.003	0.997	0.000
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.997	0.002
M50.8 Other cervical disk disorders	0.003	0.997	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.002	0.997	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.002	0.997	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.001	0.997	0.002
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.002	0.997	0.000
R16.1 Splenomegaly, not elsewhere classified	0.003	0.997	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.002	0.997	0.000
J31.2 Chronic pharyngitis	0.000	0.997	0.002
Q26 Congenital malformations of great veins	0.002	0.997	0.000
Q25 Congenital malformations of great arteries	0.002	0.997	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.002	0.997	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.002	0.997	0.000
N39.8 Other specified disorders of urinary system	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
Q27.4 Congenital phlebectasia	0.002	0.998	0.000
Q27.2 Other congenital malformations of renal artery	0.002	0.998	0.000
Q27.1 Congenital renal artery stenosis	0.002	0.998	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.002	0.998	0.000
Q23.1 Congenital insufficiency of aortic valve	0.002	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.998	0.002
F31 Bipolar affective disorder	0.002	0.998	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
K09 Cysts of oral region, not elsewhere classified	0.002	0.998	0.000
C91.1 Chronic lymphocytic leukaemia	0.002	0.998	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.002	0.998	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.002	0.998	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.002	0.998	0.000
Q28.3 Other malformations of cerebral vessels	0.002	0.998	0.000
Q28.1 Other malformations of precerebral vessels	0.002	0.998	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
Q11.1 Other anophthalmos	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
C83.0 Small cell (diffuse)	0.002	0.998	0.000
M50.9 Cervical disk disorder, unspecified	0.002	0.998	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.002	0.998	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.002	0.998	0.000
M10.94 Gout, unspecified (Hand)	0.002	0.998	0.000
I44.1 Atrioventricular block, second degree	0.000	0.998	0.002
M10.9 Gout, unspecified	0.002	0.998	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.002	0.998	0.000
M10.92 Gout, unspecified (Upper arm)	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
J31.1 Chronic nasopharyngitis	0.000	0.998	0.002
R74 Abnormal serum enzyme levels	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.002	0.998	0.000
K09.2 Other cysts of jaw	0.002	0.998	0.000
M70.22 Olecranon bursitis-Upper arm	0.000	0.998	0.002
Q39 Congenital malformations of oesophagus	0.002	0.998	0.000
Q39.6 Diverticulum of oesophagus	0.002	0.998	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.001	0.998	0.001
Q50.5 Embryonic cyst of broad ligament	0.001	0.998	0.001
Q50.3 Other congenital malformations of ovary	0.001	0.998	0.001
Q50.2 Congenital torsion of ovary	0.001	0.998	0.001
Q50.1 Developmental ovarian cyst	0.001	0.998	0.001
Q50.0 Congenital absence of ovary	0.001	0.998	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
Q17 Other congenital malformations of ear	0.002	0.998	0.000
Q80-Q89 Other congenital malformations	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
K09.9 Cyst of oral region, unspecified	0.002	0.998	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.002	0.998	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.002	0.998	0.000
Q20.6 Isomerism of atrial appendages	0.002	0.998	0.000
Q20.5 Discordant atrioventricular connexion	0.002	0.998	0.000
Q20.4 Double inlet ventricle	0.002	0.998	0.000
Q20.3 Discordant ventriculoarterial connexion	0.002	0.998	0.000
Q20.2 Double outlet left ventricle	0.002	0.998	0.000
Q20.1 Double outlet right ventricle	0.002	0.998	0.000
Q20.0 Common arterial trunk	0.002	0.998	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.002	0.998	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.002	0.998	0.000
Q22.6 Hypoplastic right heart syndrome	0.002	0.998	0.000
Q22.5 Ebstein's anomaly	0.002	0.998	0.000
Q22.4 Congenital tricuspid stenosis	0.002	0.998	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.002	0.998	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.002	0.998	0.000
Q22.1 Congenital pulmonary valve stenosis	0.002	0.998	0.000
Q22.0 Pulmonary valve atresia	0.002	0.998	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.002	0.998	0.000
Q25.8 Other congenital malformations of great arteries	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.002	0.998	0.000
Q25.6 Stenosis of pulmonary artery	0.002	0.998	0.000
Q25.5 Atresia of pulmonary artery	0.002	0.998	0.000
Q25.4 Other congenital malformations of aorta	0.002	0.998	0.000
Q25.3 Stenosis of aorta	0.002	0.998	0.000
Q25.2 Atresia of aorta	0.002	0.998	0.000
Q25.1 Coarctation of aorta	0.002	0.998	0.000
Q25.0 Patent ductus arteriosus	0.002	0.998	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.002	0.998	0.000
Q26.8 Other congenital malformations of great veins	0.002	0.998	0.000
Q26.6 Portal vein-hepatic artery fistula	0.002	0.998	0.000
Q26.5 Anomalous portal venous connexion	0.002	0.998	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.002	0.998	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.002	0.998	0.000
Q26.1 Persistent left superior vena cava	0.002	0.998	0.000
Q26.0 Congenital stenosis of vena cava	0.002	0.998	0.000
D68.8 Other specified coagulation defects	0.002	0.998	0.000
Q10.0 Congenital ptosis	0.002	0.998	0.000
F31.8 Other bipolar affective disorders	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
Q45 Other congenital malformations of digestive system	0.002	0.998	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.002	0.998	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.002	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.002	0.998	0.000
Q89 Other congenital malformations, not elsewhere classified	0.002	0.998	0.000
Q17.5 Prominent ear	0.002	0.998	0.000
W29.9 Unspecified place	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.001	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.002	0.998	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.002	0.998	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.002	0.998	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.002	0.998	0.000
Q15 Other congenital malformations of eye	0.002	0.998	0.000
Q14 Congenital malformations of posterior segment of eye	0.002	0.998	0.000
Q13 Congenital malformations of anterior segment of eye	0.002	0.998	0.000
M65-M68 Disorders of synovium and tendon	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
Q11.3 Macrophthalmos	0.002	0.998	0.000
Q11.2 Microphthalmos	0.002	0.998	0.000
Q11.0 Cystic eyeball	0.002	0.998	0.000
M10.98 Gout, unspecified (Other)	0.002	0.998	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M10.93 Gout, unspecified (Forearm)	0.002	0.998	0.000
M10.91 Gout, unspecified (Shoulder region)	0.002	0.998	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.002	0.998	0.000
Q35-Q37 Cleft lip and cleft palate	0.002	0.998	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.002	0.998	0.000
M10.90 Gout, unspecified (Multiple sites)	0.002	0.998	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.002	0.998	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.002	0.998	0.000
Q83 Congenital malformations of breast	0.002	0.998	0.000
Q96 Turner's syndrome	0.002	0.998	0.000
Q39.9 Congenital malformation of oesophagus, unspecified	0.002	0.998	0.000
Q39.8 Other congenital malformations of oesophagus	0.002	0.998	0.000
Q39.5 Congenital dilatation of oesophagus	0.002	0.998	0.000
Q39.3 Congenital stenosis and stricture of oesophagus	0.002	0.998	0.000
Q39.2 Congenital tracheooesophageal fistula without atresia	0.002	0.998	0.000
Q39.1 Atresia of oesophagus with tracheooesophageal fistula	0.002	0.998	0.000
Q39.0 Atresia of oesophagus without fistula	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q10.7 Congenital malformation of orbit	0.002	0.998	0.000
Q10.6 Other congenital malformations of lachrymal apparatus	0.002	0.998	0.000
Q10.5 Congenital stenosis and stricture of lachrymal duct	0.002	0.998	0.000
Q10.4 Absence and agenesis of lachrymal apparatus	0.002	0.998	0.000
Q10.3 Other congenital malformations of eyelid	0.002	0.998	0.000
Q10.2 Congenital entropion	0.002	0.998	0.000
Q10.1 Congenital ectropion	0.002	0.998	0.000
H61.9 Disorder of external ear, unspecified	0.000	0.998	0.002
Q17.9 Congenital malformation of ear, unspecified	0.002	0.998	0.000
Q17.8 Other specified congenital malformations of ear	0.002	0.998	0.000
Q17.4 Misplaced ear	0.002	0.998	0.000
Q17.3 Other misshapen ear	0.002	0.998	0.000
Q17.2 Microtia	0.002	0.998	0.000
Q17.1 Macrotia	0.002	0.998	0.000
Q17.0 Accessory auricle	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.002	0.998	0.000
Q84 Other congenital malformations of integument	0.002	0.998	0.000
Q81 Epidermolysis bullosa	0.002	0.998	0.000
Q80 Congenital ichthyosis	0.002	0.998	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.002	0.998	0.000
Q82 Other congenital malformations of skin	0.002	0.998	0.000
Q00-Q07 Congenital malformations of the nervous system	0.002	0.998	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.002	0.998	0.000
H61.2 Impacted cerumen	0.000	0.998	0.002
Z00.0 General medical examination	0.002	0.998	0.000
Q21 Congenital malformations of cardiac septa	0.002	0.998	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.002	0.998	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
A08.4 Viral intestinal infection, unspecified	0.002	0.998	0.000
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.001	0.998	0.000
Q40.8 Other specified congenital malformations of upper alimentary tract	0.001	0.998	0.000
Q40.3 Congenital malformation of stomach, unspecified	0.001	0.998	0.000
Q40.2 Other specified congenital malformations of stomach	0.001	0.998	0.000
Q40.1 Congenital hiatus hernia	0.001	0.998	0.000
Q40.0 Congenital hypertrophic pyloric stenosis	0.001	0.998	0.000
Q41.9 Congenital absence, atresia and stenosis of small intestine, part unspecified	0.001	0.998	0.000
Q41.8 Congenital absence, atresia and stenosis of other specified parts of small intestine	0.001	0.998	0.000
Q41.2 Congenital absence, atresia and stenosis of ileum	0.001	0.998	0.000
Q41.1 Congenital absence, atresia and stenosis of jejunum	0.001	0.998	0.000
Q41.0 Congenital absence, atresia and stenosis of duodenum	0.001	0.998	0.000
Q42.9 Congenital absence, atresia and stenosis of large intestine, part unspecified	0.001	0.998	0.000
Q42.8 Congenital absence, atresia and stenosis of other parts of large intestine	0.001	0.998	0.000
Q42.3 Congenital absence, atresia and stenosis of anus without fistula	0.001	0.998	0.000
Q42.2 Congenital absence, atresia and stenosis of anus with fistula	0.001	0.998	0.000
Q42.1 Congenital absence, atresia and stenosis of rectum without fistula	0.001	0.998	0.000
Q42.0 Congenital absence, atresia and stenosis of rectum with fistula	0.001	0.998	0.000
Q45.9 Congenital malformation of digestive system, unspecified	0.001	0.998	0.000
Q45.8 Other specified congenital malformations of digestive system	0.001	0.998	0.000
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.998	0.000
Q45.2 Congenital pancreatic cyst	0.001	0.998	0.000
Q45.1 Annular pancreas	0.001	0.998	0.000
Q45.0 Agenesis, aplasia and hypoplasia of pancreas	0.001	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
Q12 Congenital lens malformations	0.001	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
M10.99 Gout, unspecified (Site unspecified)	0.002	0.998	0.000
H61.1 Non-infective disorders of pinna	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.002	0.998	0.000
D24 Benign neoplasm of breast	0.002	0.998	0.000
I08 Multiple valve diseases	0.002	0.998	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.998	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.998	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.998	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.998	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.998	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.998	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.998	0.000
Q90 Down's syndrome	0.001	0.998	0.000
K65-K67 Diseases of peritoneum	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.998	0.000
Q89.8 Other specified congenital malformations	0.001	0.998	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.998	0.000
Q89.4 Conjoined twins	0.001	0.998	0.000
Q89.3 Situs inversus	0.001	0.998	0.000
Q89.1 Congenital malformations of adrenal gland	0.001	0.998	0.000
Q89.0 Congenital malformations of spleen	0.001	0.998	0.000
I09 Other rheumatic heart diseases	0.002	0.998	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.001	0.998	0.000
Q55 Other congenital malformations of male genital organs	0.001	0.998	0.000
Q52 Other congenital malformations of female genitalia	0.001	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.998	0.000
Q53 Undescended testicle	0.001	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.001	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.002	0.998	0.000
Q13.9 Congenital malformation of anterior segment of eye, unspecified	0.001	0.998	0.000
Q13.8 Other congenital malformations of anterior segment of eye	0.001	0.998	0.000
Q13.5 Blue sclera	0.001	0.998	0.000
Q13.4 Other congenital corneal malformations	0.001	0.998	0.000
Q13.3 Congenital corneal opacity	0.001	0.998	0.000
Q13.2 Other congenital malformations of iris	0.001	0.998	0.000
Q13.1 Absence of iris	0.001	0.998	0.000
Q13.0 Coloboma of iris	0.001	0.998	0.000
Q14.9 Congenital malformation of posterior segment of eye, unspecified	0.001	0.998	0.000
Q14.8 Other congenital malformations of posterior segment of eye	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations