TreeWAS – Variant ID: rs2645430

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.900	0.100	0.000
I10-I15 Hypertensive diseases	0.204	0.796	0.000
I15 Secondary hypertension	0.165	0.834	0.000
I13 Hypertensive heart and renal disease	0.152	0.848	0.000
I15.2 Hypertension secondary to endocrine disorders	0.130	0.870	0.000
I15.8 Other secondary hypertension	0.126	0.874	0.000
I15.1 Hypertension secondary to other renal disorders	0.123	0.877	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.121	0.879	0.000
I15.9 Seconday hypertension, unspecified	0.120	0.880	0.000
I15.0 Renovascular hypertension	0.116	0.884	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.109	0.891	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.109	0.891	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.102	0.898	0.000
I12 Hypertensive renal disease	0.093	0.907	0.000
I11 Hypertensive heart disease	0.081	0.919	0.000
I12.9 Hypertensive renal disease without renal failure	0.050	0.950	0.000
I12.0 Hypertensive renal disease with renal failure	0.045	0.955	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.039	0.961	0.001
I11.9 Hypertensive heart disease without (congestive) heart failure	0.034	0.966	0.000
I83.0 Varicose veins of lower extremities with ulcer	0.013	0.987	0.000
L03.1 Cellulitis of other parts of limb	0.012	0.988	0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.011	0.989	0.000
I83 Varicose veins of lower extremities	0.010	0.990	0.000
S00.8 Superficial injury of other parts of head	0.010	0.990	0.000
N30.8 Other cystitis	0.000	0.992	0.008
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.992	0.008
I83.1 Varicose veins of lower extremities with inflammation	0.008	0.992	0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.008	0.992	0.000
R40.0 Somnolence	0.008	0.992	0.000
T82.1 Mechanical complication of cardiac electronic device	0.007	0.993	0.000
Z71.6 Tobacco abuse counselling	0.000	0.993	0.007
L03.8 Cellulitis of other sites	0.007	0.993	0.000
E66.8 Other obesity	0.006	0.994	0.000
E66.9 Obesity, unspecified	0.006	0.994	0.000
N10 Acute tubulo-interstitial nephritis	0.006	0.994	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.994	0.006
L03 Cellulitis	0.006	0.994	0.000
E66 Obesity	0.005	0.995	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.995	0.005
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.005	0.995	0.000
N13.8 Other obstructive and reflux uropathy	0.005	0.995	0.000
E66.0 Obesity due to excess calories	0.005	0.995	0.000
L08.8 Other specified local infections of skin and subcutaneous tissue	0.005	0.995	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.005	0.995	0.000
C50.1 Central portion of breast	0.005	0.995	0.000
N13 Obstructive and reflux uropathy	0.005	0.995	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.004	0.996	0.000
N10-N16 Renal tubulo-interstitial diseases	0.004	0.996	0.000
R40 Somnolence, stupor and coma	0.004	0.996	0.000
E66.1 Drug-induced obesity	0.004	0.996	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.004	0.996	0.000
L03.3 Cellulitis of trunk	0.004	0.996	0.000
D34 Benign neoplasm of thyroid gland	0.004	0.996	0.000
E04.2 Non-toxic multinodular goitre	0.004	0.996	0.000
R40.2 Coma, unspecified	0.004	0.996	0.000
N13.4 Hydroureter	0.004	0.996	0.000
N13.3 Other and unspecified hydronephrosis	0.004	0.996	0.000
N30.2 Other chronic cystitis	0.000	0.996	0.004
N14.4 Toxic nephropathy, not elsewhere classified	0.003	0.997	0.000
N14.3 Nephropathy induced by heavy metals	0.003	0.997	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.003	0.997	0.000
N14.0 Analgesic nephropathy	0.003	0.997	0.000
N30 Cystitis	0.000	0.997	0.003
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.003	0.997	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.003	0.997	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.003	0.997	0.000
H43.8 Other disorders of vitreous body	0.000	0.997	0.003
L08 Other local infections of skin and subcutaneous tissue	0.003	0.997	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.997	0.003
R56.8 Other and unspecified convulsions	0.003	0.997	0.000
B91 Sequelae of poliomyelitis	0.003	0.997	0.000
K80.4 Calculus of bile duct with cholecystitis	0.000	0.997	0.003
L08.0 Pyoderma	0.003	0.997	0.000
N30.4 Irradiation cystitis	0.000	0.997	0.003
E89.0 Postprocedural hypothyroidism	0.003	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.003	0.997	0.000
R40.1 Stupor	0.003	0.997	0.000
N15 Other renal tubulo-interstitial diseases	0.003	0.997	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.003	0.997	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.003	0.997	0.000
L03.0 Cellulitis of finger and toe	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.003	0.997	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.003	0.997	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.002	0.997	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.002	0.997	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.002	0.997	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.002	0.997	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.002	0.997	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.002	0.997	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.997	0.003
L00-L08 Infections of the skin and subcutaneous tissue	0.003	0.997	0.000
N11 Chronic tubulo-interstitial nephritis	0.003	0.997	0.000
L08.1 Erythrasma	0.002	0.997	0.000
L03.2 Cellulitis of face	0.002	0.997	0.000
I44.1 Atrioventricular block, second degree	0.000	0.997	0.002
N30.9 Cystitis, unspecified	0.000	0.998	0.002
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.000	0.998	0.002
L01 Impetigo	0.002	0.998	0.000
M66.2 Spontaneous rupture of extensor tendons	0.002	0.998	0.000
K80 Cholelithiasis	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.998	0.002
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.002	0.998	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
L01.0 Impetigo [any organism] [any site]	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.998	0.002
N42.8 Other specified disorders of prostate	0.000	0.998	0.002
H81.9 Disorder of vestibular function, unspecified	0.002	0.998	0.000
N76.2 Acute vulvitis	0.002	0.998	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.002	0.998	0.000
L00 Staphylococcal scalded skin syndrome	0.002	0.998	0.000
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
N95.1 Menopausal and female climacteric states	0.002	0.998	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.998	0.002
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.998	0.002
K43.0 Ventral hernia with obstruction, without gangrene	0.002	0.998	0.000
K82.3 Fistula of gallbladder	0.000	0.998	0.002
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
L71.9 Rosacea, unspecified	0.002	0.998	0.000
N90.7 Vulvar cyst	0.000	0.998	0.002
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.002
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
L01.1 Impetiginisation of other dermatoses	0.002	0.998	0.000
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.002	0.998	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.002	0.998	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.002	0.998	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.002	0.998	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.002	0.998	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.002	0.998	0.000
E89.2 Postprocedural hypoparathyroidism	0.002	0.998	0.000
N13.6 Pyonephrosis	0.002	0.998	0.000
K80.3 Calculus of bile duct with cholangitis	0.000	0.998	0.002
N30.3 Trigonitis	0.000	0.998	0.002
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
J45.9 Asthma, unspecified	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.998	0.000
C62.9 Testis, unspecified	0.000	0.998	0.002
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.002	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.002	0.998	0.000
K80.8 Other cholelithiasis	0.000	0.998	0.002
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.002	0.998	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.002	0.998	0.000
D47.2 Monoclonal gammopathy	0.002	0.998	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.002	0.998	0.000
L04 Acute lymphadenitis	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
Y49.2 Other and unspecified antidepressants	0.000	0.998	0.002
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.002	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.002	0.998	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.002	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.002	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.002	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.002	0.998	0.000
E24 Cushing's syndrome	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
L81.9 Disorder of pigmentation, unspecified	0.002	0.998	0.000
Z72.0 Tobacco use	0.002	0.998	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.000	0.998	0.002
E23.0 Hypopituitarism	0.002	0.998	0.000
M66.1 Rupture of synovium	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
K82 Other diseases of gallbladder	0.000	0.998	0.002
M66.09 Rupture of popliteal cyst-Site unspec	0.002	0.998	0.000
M66.08 Rupture of popliteal cyst-Other	0.002	0.998	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.002	0.998	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.002	0.998	0.000
M66.04 Rupture of popliteal cyst-Hand	0.002	0.998	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.002	0.998	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.002	0.998	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.002	0.998	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.002	0.998	0.000
R77.8 Other specified abnormalities of plasma proteins	0.000	0.998	0.002
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.998	0.001
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
N18.5 Chronic kidney disease, stage 5	0.002	0.998	0.000
S00 Superficial injury of head	0.002	0.998	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.002	0.998	0.000
L02 Cutaneous abscess, furuncle and carbuncle	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.001
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.002	0.998	0.000
M21.0 Valgus deformity, not elsewhere classified	0.002	0.998	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.002	0.998	0.000
L71.8 Other rosacea	0.002	0.998	0.000
N76.5 Ulceration of vagina	0.002	0.998	0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
M67.0 Short Achilles tendon (acquired)	0.002	0.998	0.000
N76.4 Abscess of vulva	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.002	0.998	0.000
K82.0 Obstruction of gallbladder	0.000	0.998	0.002
L04.1 Acute lymphadenitis of trunk	0.001	0.998	0.000
R44.0 Auditory hallucinations	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.002	0.998	0.000
E65-E68 Obesity and other hyperalimentation	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
K82.1 Hydrops of gallbladder	0.000	0.998	0.002
S00.4 Superficial injury of ear	0.002	0.998	0.000
S00.3 Superficial injury of nose	0.002	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
L04.8 Acute lymphadenitis of other sites	0.001	0.998	0.000
L04.3 Acute lymphadenitis of lower limb	0.001	0.998	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.002
R44.1 Visual hallucinations	0.002	0.998	0.000
N76 Other inflammation of vagina and vulva	0.002	0.998	0.000
R43 Disturbances of smell and taste	0.002	0.998	0.000
C76.0 Head, face and neck	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
L04.2 Acute lymphadenitis of upper limb	0.001	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.001	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.001	0.998	0.000
E24.1 Nelson's syndrome	0.001	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
M66.3 Spontaneous rupture of flexor tendons	0.001	0.998	0.000
N30.0 Acute cystitis	0.000	0.998	0.001
T31.0 Burns involving less than 10% of body surface	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
C44.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
H81.3 Other peripheral vertigo	0.002	0.998	0.000
K22.7 Barrett's oesophagus	0.002	0.998	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.001	0.998	0.000
R43.0 Anosmia	0.001	0.998	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.002	0.998	0.000
L71 Rosacea	0.002	0.998	0.000
M66.19 Rupture of synovium (Site unspecified)	0.001	0.998	0.000
M66.18 Rupture of synovium (Other)	0.001	0.998	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.001	0.998	0.000
M66.16 Rupture of synovium (Lower leg)	0.001	0.998	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.001	0.998	0.000
M66.14 Rupture of synovium (Hand)	0.001	0.998	0.000
M66.13 Rupture of synovium (Forearm)	0.001	0.998	0.000
M66.12 Rupture of synovium (Upper arm)	0.001	0.998	0.000
M66.11 Rupture of synovium (Shoulder region)	0.001	0.998	0.000
M66.10 Rupture of synovium (Multiple sites)	0.001	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.002	0.998	0.000
F40.0 Agoraphobia	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.001	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.000	0.998	0.001
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.001	0.998	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.001	0.998	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.001	0.998	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
M25.84 Other specified joint disorders (Hand)	0.001	0.998	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.001	0.998	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.001	0.998	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.001	0.998	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.001	0.998	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.001	0.998	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.001	0.998	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.001	0.998	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.001	0.998	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.001	0.998	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.001	0.999	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.001	0.999	0.000
M67.47 Ganglion, ankle and foot	0.001	0.999	0.000
E24.2 Drug-induced Cushing's syndrome	0.001	0.999	0.000
K81.0 Acute cholecystitis	0.000	0.999	0.001
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.999	0.001
E67 Other hyperalimentation	0.001	0.999	0.000
E68 Sequelae of hyperalimentation	0.001	0.999	0.000
K43 Ventral hernia	0.001	0.999	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.000	0.999	0.001
E22.0 Acromegaly and pituitary gigantism	0.001	0.999	0.000
I35.1 Aortic (valve) insufficiency	0.001	0.999	0.000
L71.1 Rhinophyma	0.001	0.999	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.001	0.999	0.000
M67.3 Transient synovitis	0.001	0.999	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.999	0.001
Q50.3 Other congenital malformations of ovary	0.000	0.999	0.001
Q50.2 Congenital torsion of ovary	0.000	0.999	0.001
Q50.1 Developmental ovarian cyst	0.000	0.999	0.001
Q50.0 Congenital absence of ovary	0.000	0.999	0.001
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.999	0.001
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.999	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.001	0.999	0.000
S52.61 Fracture of lower end of both ulna and radius (open)	0.000	0.999	0.001
L04.0 Acute lymphadenitis of face, head and neck	0.001	0.999	0.000
M67.4 Ganglion	0.001	0.999	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.001	0.999	0.000
S69.8 Other specified injuries of wrist and hand	0.000	0.999	0.001
H81 Disorders of vestibular function	0.001	0.999	0.000
K35 Acute appendicitis	0.000	0.999	0.001
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.999	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.999	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.999	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.999	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.999	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.999	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.001	0.999	0.000
C71.1 Frontal lobe	0.000	0.999	0.001
E23.2 Diabetes insipidus	0.001	0.999	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.999	0.000
L04.9 Acute lymphadenitis, unspecified	0.001	0.999	0.000
L13.0 Dermatitis herpetiformis	0.001	0.999	0.000
N76.6 Ulceration of vulva	0.001	0.999	0.000
R43.2 Parageusia	0.001	0.999	0.000
S00.5 Superficial injury of lip and oral cavity	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.001	0.999	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.999	0.000
G93.4 Encephalopathy, unspecified	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.999	0.001
D13.0 Oesophagus	0.001	0.999	0.000
K35.9 Acute appendicitis, unspecified	0.000	0.999	0.001
L71.0 Perioral dermatitis	0.001	0.999	0.000
R44.2 Other hallucinations	0.001	0.999	0.000
F99 Mental disorder, not otherwise specified	0.000	0.999	0.001
R44 Other symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
B90-B94 Sequelae of infectious and parasitic diseases	0.001	0.999	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.001	0.999	0.000
R77.9 Abnormality of plasma protein, unspecified	0.000	0.999	0.001
S00.0 Superficial injury of scalp	0.001	0.999	0.000
Y84.0 Cardiac catheterisation	0.000	0.999	0.001
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.999	0.001
J45.1 Nonallergic asthma	0.001	0.999	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.001	0.999	0.000
R43.1 Parosmia	0.001	0.999	0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.999	0.001
D13.2 Duodenum	0.001	0.999	0.000
L81.2 Freckles	0.001	0.999	0.000
Z43.4 Attention to other artificial openings of digestive tract	0.000	0.999	0.001
E04 Other non-toxic goitre	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.000	0.999	0.001
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.001	0.999	0.000
E67.8 Other specified hyperalimentation	0.001	0.999	0.000
E67.3 Hypervitaminosis D	0.001	0.999	0.000
E67.2 Megavitamin-B6 syndrome	0.001	0.999	0.000
E67.1 Hypercarotenaemia	0.001	0.999	0.000
E67.0 Hypervitaminosis A	0.001	0.999	0.000
H81.4 Vertigo of central origin	0.001	0.999	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.001	0.999	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.001	0.999	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.001	0.999	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.001	0.999	0.000
K43.4 Parastomal hernia with gangrene	0.001	0.999	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.001	0.999	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.001	0.999	0.000
K43.1 Ventral hernia with gangrene	0.001	0.999	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.001	0.999	0.000
N76.3 Subacute and chronic vulvitis	0.001	0.999	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.999	0.001
M67.49 Ganglion, multiple sites	0.001	0.999	0.000
M67.45 Ganglion, hip	0.001	0.999	0.000
N76.8 Other specified inflammation of vagina and vulva	0.001	0.999	0.000
R46.4 Slowness and poor responsiveness	0.001	0.999	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.999	0.001
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.999	0.001
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.999	0.001
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.999	0.000
C24.0 Extrahepatic bile duct	0.000	0.999	0.001
H81.2 Vestibular neuronitis	0.001	0.999	0.000
K82.2 Perforation of gallbladder	0.000	0.999	0.001
R63.0 Anorexia	0.000	0.999	0.001
Z49.1 Extracorporeal dialysis	0.001	0.999	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.999	0.001
J45.8 Mixed asthma	0.001	0.999	0.000
B90 Sequelae of tuberculosis	0.001	0.999	0.000
B92 Sequelae of leprosy	0.001	0.999	0.000
J45 Asthma	0.001	0.999	0.000
R56 Convulsions, not elsewhere classified	0.001	0.999	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.001	0.999	0.001
S42.41 Fracture of lower end of humerus (open)	0.000	0.999	0.001
E28.2 Polycystic ovarian syndrome	0.001	0.999	0.000
F40.9 Phobic anxiety disorder, unspecified	0.001	0.999	0.000
H81.1 Benign paroxysmal vertigo	0.001	0.999	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.000	0.999	0.001
Z84.1 Family history of disorders of the kidney and ureter	0.001	0.999	0.000
E04.8 Other specified non-toxic goitre	0.001	0.999	0.000
E31.0 Autoimmune polyglandular failure	0.001	0.999	0.000
I72.3 Aneurysm of iliac artery	0.000	0.999	0.001
L43.8 Other lichen planus	0.000	0.999	0.001
S09.8 Other specified injuries of head	0.001	0.999	0.000
U80.0 Penicillin resistant agent	0.001	0.999	0.000
B94.9 Sequelae of unspecified infectious or parasitic disease	0.001	0.999	0.000
K38.0 Hyperplasia of appendix	0.000	0.999	0.001
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.001	0.999	0.000
M16.9 Coxarthrosis, unspecified	0.001	0.999	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.001	0.999	0.000
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.001	0.999	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.001	0.999	0.000
Z49.0 Preparatory care for dialysis	0.001	0.999	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.001	0.999	0.000
B90.9 Sequelae of respiratory and unspecified tuberculosis	0.001	0.999	0.000
B90.8 Sequelae of tuberculosis of other organs	0.001	0.999	0.000
B90.2 Sequelae of tuberculosis of bones and joints	0.001	0.999	0.000
B90.1 Sequelae of genito-urinary tuberculosis	0.001	0.999	0.000
B90.0 Sequelae of central nervous system tuberculosis	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.001	0.999	0.000
H18.0 Corneal pigmentations and deposits	0.001	0.999	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.000	0.999	0.001
K38.1 Appendicular concretions	0.000	0.999	0.001
K82.9 Disease of gallbladder, unspecified	0.000	0.999	0.001
R74.8 Abnormal levels of other serum enzymes	0.000	0.999	0.001
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
D16.1 Short bones of upper limb	0.000	0.999	0.001
D44.0 Thyroid gland	0.001	0.999	0.000
J95.8 Other postprocedural respiratory disorders	0.000	0.999	0.001
L13.9 Bullous disorder, unspecified	0.001	0.999	0.000
N42.3 Dysplasia of prostate	0.000	0.999	0.001
W29.9 Unspecified place	0.001	0.999	0.000
E31 Polyglandular dysfunction	0.001	0.999	0.000
E29 Testicular dysfunction	0.001	0.999	0.000
E28 Ovarian dysfunction	0.001	0.999	0.000
L13 Other bullous disorders	0.001	0.999	0.000
U89 Agent resistant to other and unspecified antibiotics	0.001	0.999	0.000
B94.2 Sequelae of viral hepatitis	0.001	0.999	0.000
B94.1 Sequelae of viral encephalitis	0.001	0.999	0.000
B94.0 Sequelae of trachoma	0.001	0.999	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.001	0.999	0.000
H53.1 Subjective visual disturbances	0.001	0.999	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.999	0.001
T88.7 Unspecified adverse effect of drug or medicament	0.001	0.999	0.000
E22 Hyperfunction of pituitary gland	0.001	0.999	0.000
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.001	0.999	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.001	0.999	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.001	0.999	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.001	0.999	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.001	0.999	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.001	0.999	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.001	0.999	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.001	0.999	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.001	0.999	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.001	0.999	0.000
C76.1 Thorax	0.000	0.999	0.001
H18.7 Other corneal deformities	0.001	0.999	0.000
S09.9 Unspecified injury of head	0.001	0.999	0.000
T43.2 Other and unspecified antidepressants	0.000	0.999	0.001
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.999	0.001
E29.9 Testicular dysfunction, unspecified	0.001	0.999	0.000
E31.9 Polyglandular dysfunction, unspecified	0.001	0.999	0.000
E31.8 Other polyglandular dysfunction	0.001	0.999	0.000
E31.1 Polyglandular hyperfunction	0.001	0.999	0.000
H40.5 Glaucoma secondary to other eye disorders	0.001	0.999	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.999	0.001
N42.1 Congestion and haemorrhage of prostate	0.000	0.999	0.001
S13.1 Dislocation of cervical vertebra	0.001	0.999	0.000
T20.2 Burn of second degree of head and neck	0.001	0.999	0.000
Z74.0 Reduced mobility	0.000	0.999	0.001
H18 Other disorders of cornea	0.001	0.999	0.000
M46.06 Spinal enthesopathy (Lumbar region)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.000	0.999	0.001
E28.9 Ovarian dysfunction, unspecified	0.001	0.999	0.000
E28.8 Other ovarian dysfunction	0.001	0.999	0.000
E28.1 Androgen excess	0.001	0.999	0.000
E28.0 Oestrogen excess	0.001	0.999	0.000
E29.8 Other testicular dysfunction	0.001	0.999	0.000
E29.0 Testicular hyperfunction	0.001	0.999	0.000
E87.7 Fluid overload	0.001	0.999	0.000
F43.9 Reaction to severe stress, unspecified	0.001	0.999	0.000
L13.8 Other specified bullous disorders	0.001	0.999	0.000
L13.1 Subcorneal pustular dermatitis	0.001	0.999	0.000
R56.0 Febrile convulsions	0.001	0.999	0.000
S69.7 Multiple injuries of wrist and hand	0.000	0.999	0.001
T25.2 Burn of second degree of ankle and foot	0.001	0.999	0.000
E20-E35 Disorders of other endocrine glands	0.001	0.999	0.000
D31.3 Choroid	0.000	0.999	0.001
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
E22.8 Other hyperfunction of pituitary gland	0.001	0.999	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations