TreeWAS – Variant ID: rs2652834

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N81.3 Complete uterovaginal prolapse	0.000	0.943	0.057
H61.2 Impacted cerumen	0.049	0.951	0.000
H61 Other disorders of external ear	0.046	0.954	0.000
H61.3 Acquired stenosis of external ear canal	0.041	0.959	0.000
H61.0 Perichondritis of external ear	0.041	0.959	0.000
H61.1 Non-infective disorders of pinna	0.039	0.961	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.966	0.034
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.031	0.969	0.000
H61.8 Other specified disorders of external ear	0.031	0.969	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.031	0.969	0.000
H60-H62 Diseases of external ear	0.030	0.970	0.000
Y45.0 Opioids and related analgesics	0.030	0.970	0.000
Y45.2 Propionic acid derivatives	0.028	0.972	0.000
H61.9 Disorder of external ear, unspecified	0.027	0.972	0.000
H60 Otitis externa	0.025	0.975	0.000
Y45.8 Other analgesics and antipyretics	0.025	0.975	0.000
Y45.1 Salicylates	0.024	0.976	0.000
Y45.4 Antirheumatics	0.022	0.977	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.022	0.977	0.000
H60.3 Other infective otitis externa	0.022	0.978	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.022	0.978	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.978	0.022
J02 Acute pharyngitis	0.000	0.979	0.021
Y45.5 4-Aminophenol derivatives	0.021	0.979	0.000
H60.1 Cellulitis of external ear	0.019	0.981	0.000
H60.4 Cholesteatoma of external ear	0.018	0.981	0.000
H60.8 Other otitis externa	0.018	0.982	0.000
H60.5 Acute otitis externa, non-infective	0.018	0.982	0.000
H60.2 Malignant otitis externa	0.017	0.983	0.000
H60.9 Otitis externa, unspecified	0.017	0.983	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.017	0.983	0.000
H60.0 Abscess of external ear	0.017	0.983	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.983	0.017
H62.8 Other disorders of external ear in diseases classified elsewhere	0.016	0.984	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.016	0.984	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
H62.2 Otitis externa in mycoses	0.016	0.984	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.016	0.984	0.000
J02.8 Acute pharyngitis due to other specified organisms	0.000	0.984	0.016
J02.0 Streptococcal pharyngitis	0.000	0.984	0.016
S62.50 Fracture of thumb (closed)	0.013	0.987	0.000
J84 Other interstitial pulmonary diseases	0.000	0.989	0.011
J84.8 Other specified interstitial pulmonary diseases	0.000	0.990	0.010
C50.5 Lower-outer quadrant of breast	0.000	0.990	0.010
M79.67 Pain in limb (Ankle and foot)	0.000	0.991	0.009
H00.1 Chalazion	0.000	0.991	0.009
J00-J06 Acute upper respiratory infections	0.000	0.992	0.008
J84.0 Alveolar and parietoalveolar conditions	0.000	0.992	0.008
Chapter VIII Diseases of the ear and mastoid process	0.008	0.992	0.000
K60.2 Anal fissure, unspecified	0.008	0.992	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.993	0.007
J01 Acute sinusitis	0.000	0.993	0.007
J00 Acute nasopharyngitis [common cold]	0.000	0.993	0.007
S62.5 Fracture of thumb	0.007	0.993	0.000
H72 Perforation of tympanic membrane	0.007	0.993	0.000
H65-H75 Diseases of middle ear and mastoid	0.007	0.993	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.007	0.993	0.000
H72.0 Central perforation of tympanic membrane	0.006	0.994	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.000	0.994	0.006
H74 Other disorders of middle ear and mastoid	0.006	0.994	0.000
J01.4 Acute pansinusitis	0.000	0.994	0.006
J01.2 Acute ethmoidal sinusitis	0.000	0.994	0.006
J01.8 Other acute sinusitis	0.000	0.994	0.006
J01.9 Acute sinusitis, unspecified	0.000	0.994	0.006
J01.1 Acute frontal sinusitis	0.000	0.994	0.006
D03.4 Melanoma in situ of scalp and neck	0.000	0.994	0.006
H71 Cholesteatoma of middle ear	0.006	0.994	0.000
D03.5 Melanoma in situ of trunk	0.000	0.994	0.006
D03 Melanoma in situ	0.000	0.994	0.006
H66 Suppurative and unspecified otitis media	0.006	0.994	0.000
G61.0 Guillain-Barre syndrome	0.000	0.994	0.006
H66.3 Other chronic suppurative otitis media	0.005	0.994	0.000
J01.3 Acute sphenoidal sinusitis	0.000	0.994	0.005
J01.0 Acute maxillary sinusitis	0.000	0.995	0.005
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.995	0.005
H68 Eustachian salpingitis and obstruction	0.005	0.995	0.000
J03 Acute tonsillitis	0.000	0.995	0.005
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
H74.4 Polyp of middle ear	0.005	0.995	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.005	0.995	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H67 Otitis media in diseases classified elsewhere	0.005	0.995	0.000
D03.6 Melanoma in situ of upper limb, including shoulder	0.000	0.995	0.005
H72.1 Attic perforation of tympanic membrane	0.005	0.995	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.995	0.005
H74.8 Other specified disorders of middle ear and mastoid	0.005	0.995	0.000
H70 Mastoiditis and related conditions	0.005	0.995	0.000
J04 Acute laryngitis and tracheitis	0.000	0.995	0.005
S51.8 Open wound of other parts of forearm	0.000	0.995	0.005
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.995	0.005
J06 Acute upper respiratory infections of multiple and unspecified sites	0.000	0.995	0.005
H66.0 Acute suppurative otitis media	0.005	0.995	0.000
J05.0 Acute obstructive laryngitis [croup]	0.000	0.995	0.005
S60.8 Other superficial injuries of wrist and hand	0.005	0.995	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.005	0.995	0.000
J05.1 Acute epiglottitis	0.000	0.995	0.005
D03.0 Melanoma in situ of lip	0.000	0.995	0.005
H74.1 Adhesive middle ear disease	0.005	0.995	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.000	0.995	0.005
H69 Other disorders of Eustachian tube	0.005	0.995	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.000	0.995	0.005
S62.51 Fracture of thumb (open)	0.004	0.995	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.004	0.995	0.000
H93.1 Tinnitus	0.005	0.995	0.000
H72.8 Other perforations of tympanic membrane	0.004	0.995	0.000
H68.1 Obstruction of Eustachian tube	0.004	0.996	0.000
D03.9 Melanoma in situ, unspecified	0.000	0.996	0.004
D03.8 Melanoma in situ of other sites	0.000	0.996	0.004
H66.1 Chronic tubotympanic suppurative otitis media	0.004	0.996	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.004	0.996	0.000
H66.4 Suppurative otitis media, unspecified	0.004	0.996	0.000
H68.0 Eustachian salpingitis	0.004	0.996	0.000
J03.8 Acute tonsillitis due to other specified organisms	0.000	0.996	0.004
J03.0 Streptococcal tonsillitis	0.000	0.996	0.004
G61 Inflammatory polyneuropathy	0.000	0.996	0.004
H70.9 Mastoiditis, unspecified	0.004	0.996	0.000
T92 Sequelae of injuries of upper limb	0.004	0.996	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.996	0.004
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.996	0.004
H80-H83 Diseases of inner ear	0.004	0.996	0.000
H74.0 Tympanosclerosis	0.004	0.996	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.004	0.996	0.000
H70.2 Petrositis	0.004	0.996	0.000
J04.2 Acute laryngotracheitis	0.000	0.996	0.004
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.996	0.004
S62.60 Fracture of other finger (closed)	0.004	0.996	0.000
J91 Pleural effusion in conditions classified elsewhere	0.004	0.996	0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.996	0.004
D03.1 Melanoma in situ of eyelid, including canthus	0.000	0.996	0.004
H70.8 Other mastoiditis and related conditions	0.004	0.996	0.000
H70.0 Acute mastoiditis	0.004	0.996	0.000
J06.8 Other acute upper respiratory infections of multiple sites	0.000	0.996	0.004
J06.0 Acute laryngopharyngitis	0.000	0.996	0.004
H70.1 Chronic mastoiditis	0.003	0.996	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.996	0.004
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.000	0.996	0.004
H74.3 Other acquired abnormalities of ear ossicles	0.003	0.996	0.000
T78.4 Allergy, unspecified	0.000	0.996	0.004
H80 Otosclerosis	0.004	0.996	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.996	0.004
H69.0 Patulous Eustachian tube	0.003	0.996	0.000
S51 Open wound of forearm	0.000	0.996	0.004
S51.9 Open wound of forearm, part unspecified	0.000	0.996	0.004
H73 Other disorders of tympanic membrane	0.003	0.996	0.000
T92.0 Sequelae of open wound of upper limb	0.003	0.996	0.000
S62 Fracture at wrist and hand level	0.004	0.996	0.000
H80.9 Otosclerosis, unspecified	0.003	0.996	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.003	0.997	0.000
H00 Hordeolum and chalazion	0.000	0.997	0.003
H90-H95 Other disorders of ear	0.003	0.997	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.003	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.003	0.997	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.003	0.997	0.000
S62.7 Multiple fractures of fingers	0.003	0.997	0.000
J04.1 Acute tracheitis	0.000	0.997	0.003
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
H69.9 Eustachian tube disorder, unspecified	0.003	0.997	0.000
J04.0 Acute laryngitis	0.000	0.997	0.003
Y40.8 Other systemic antibiotics	0.003	0.997	0.000
G61.1 Serum neuropathy	0.000	0.997	0.003
T88.4 Failed or difficult intubation	0.000	0.997	0.003
S62.6 Fracture of other finger	0.003	0.997	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.000	0.997	0.003
Y46.2 Hydantoin derivatives	0.003	0.997	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.003	0.997	0.000
J03.9 Acute tonsillitis, unspecified	0.000	0.997	0.003
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.000	0.997	0.003
Y40 Systemic antibiotics	0.003	0.997	0.000
J82 Pulmonary eosinophilia, not elsewhere classified	0.000	0.997	0.003
S62.71 Multiple fractures of fingers (open)	0.003	0.997	0.000
M94.8 Other specified disorders of cartilage	0.000	0.997	0.003
S51.7 Multiple open wounds of forearm	0.000	0.997	0.003
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.003	0.997	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.001	0.997	0.002
K81.0 Acute cholecystitis	0.003	0.997	0.000
Y40.3 Macrolides	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.003	0.997	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.003
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.003
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.997	0.003
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.003	0.997	0.000
S62.70 Multiple fractures of fingers (closed)	0.003	0.997	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.003	0.997	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.000	0.997	0.003
H80.8 Other otosclerosis	0.003	0.997	0.000
H80.2 Cochlear otosclerosis	0.003	0.997	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.003	0.997	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.003	0.997	0.000
S62.1 Fracture of other carpal bone(s)	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.997	0.003
Y53 Agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.997	0.003
Y49 Psychotropic drugs, not elsewhere classified	0.003	0.997	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.997	0.003
D72.8 Other specified disorders of white blood cells	0.003	0.997	0.000
H93.9 Disorder of ear, unspecified	0.003	0.997	0.000
F23 Acute and transient psychotic disorders	0.003	0.997	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.997	0.003
F23.9 Acute and transient psychotic disorder, unspecified	0.003	0.997	0.000
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
H93.3 Disorders of acoustic nerve	0.003	0.997	0.000
Y46.7 Anti-Parkinsonism drugs	0.003	0.997	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.003	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
Y40.6 Rifamycins	0.003	0.997	0.000
Y46.4 Iminostilbenes	0.003	0.997	0.000
F25.9 Schizoaffective disorder, unspecified	0.003	0.997	0.000
H18.8 Other specified disorders of cornea	0.000	0.997	0.003
M85.4 Solitary bone cyst	0.000	0.997	0.003
H94 Other disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
J80 Adult respiratory distress syndrome	0.000	0.997	0.003
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.997	0.003
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.000	0.997	0.003
D06.9 Cervix, unspecified	0.000	0.997	0.003
M85 Other disorders of bone density and structure	0.000	0.997	0.003
M43.16 Spondylolisthesis (Lumbar region)	0.003	0.997	0.000
M94 Other disorders of cartilage	0.000	0.997	0.003
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.997	0.003
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.997	0.003
K92.0 Haematemesis	0.003	0.997	0.000
Y47.1 Benzodiazepines	0.003	0.997	0.000
M84 Disorders of continuity of bone	0.000	0.997	0.003
M94.88 Other specified disorders of cartilage (Other)	0.000	0.997	0.003
Y59 Other and unspecified vaccines and biological substances	0.002	0.997	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.002	0.997	0.000
Y46.8 Antispasticity drugs	0.002	0.997	0.000
Y46.3 Deoxybarbiturates	0.002	0.997	0.000
Y46.1 Oxazolidinediones	0.002	0.997	0.000
Y46.0 Succinimides	0.002	0.997	0.000
Y53.2 Stimulant laxatives	0.002	0.997	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.997	0.003
M94.9 Disorder of cartilage, unspecified	0.000	0.997	0.002
Y40.2 Chloramphenicol group	0.002	0.997	0.000
H93.8 Other specified disorders of ear	0.002	0.997	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.000	0.997	0.002
M94.83 Other specified disorders of cartilage (Forearm)	0.000	0.997	0.002
M94.82 Other specified disorders of cartilage (Upper arm)	0.000	0.997	0.002
M94.80 Other specified disorders of cartilage (Multiple sites)	0.000	0.997	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.003	0.997	0.000
K35.8 Acute appendicitis, other and unspecified	0.003	0.997	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.997	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.997	0.000
M80 Osteoporosis with pathological fracture	0.000	0.997	0.002
Y50 Central nervous system stimulants, not elsewhere classified	0.002	0.997	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.000	0.997	0.002
F25 Schizoaffective disorders	0.002	0.997	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.001	0.998	0.002
S51.0 Open wound of elbow	0.000	0.998	0.002
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
Y46.6 Other and unspecified antiepileptics	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
F23.3 Other acute predominantly delusional psychotic disorders	0.002	0.998	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
Y58 Bacterial vaccines	0.002	0.998	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.000	0.998	0.002
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.002	0.998	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.000	0.998	0.002
Y49.0 Tricyclic and tetracyclic antidepressants	0.002	0.998	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
S62.2 Fracture of first metacarpal bone	0.002	0.998	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
D06 Carcinoma in situ of cervix uteri	0.000	0.998	0.002
S62.10 Fracture of other carpal bone(s) (closed)	0.002	0.998	0.000
H18.4 Corneal degeneration	0.000	0.998	0.002
M46.9 Inflammatory spondylopathy, unspecified	0.000	0.998	0.002
Y40.4 Tetracyclines	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.000	0.998	0.002
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.000	0.998	0.002
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.002	0.998	0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia	0.002	0.998	0.000
Y46.5 Valproic acid	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y53.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Y53.3 Saline and osmotic laxatives	0.002	0.998	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.998	0.002
H18.5 Hereditary corneal dystrophies	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.001	0.998	0.002
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
H18 Other disorders of cornea	0.000	0.998	0.002
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.998	0.002
Y49.2 Other and unspecified antidepressants	0.002	0.998	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
Y53.7 Emetics	0.002	0.998	0.000
Y53.5 Digestants	0.002	0.998	0.000
Y53.0 Histamine H2-receptor antagonists	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
M85.9 Disorder of bone density and structure, unspecified	0.000	0.998	0.002
M85.6 Other cyst of bone	0.000	0.998	0.002
Q83.1 Accessory breast	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
F23.2 Acute schizophrenia-like psychotic disorder	0.002	0.998	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.998	0.000
M94.2 Chondromalacia	0.000	0.998	0.002
Z99.1 Dependence on respirator	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.002
J06.9 Acute upper respiratory infection, unspecified	0.000	0.998	0.002
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.002	0.998	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.002	0.998	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.002	0.998	0.000
Y47.4 Bromine compounds	0.002	0.998	0.000
Y47.3 Paraldehyde	0.002	0.998	0.000
Y47.2 Chloral derivatives	0.002	0.998	0.000
Y47.0 Barbiturates, not elsewhere classified	0.002	0.998	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.998	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
D27 Benign neoplasm of ovary	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.000	0.998	0.002
A41.1 Septicaemia due to other specified staphylococcus	0.000	0.998	0.002
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.998	0.002
M85.48 Solitary bone cyst (Other)	0.000	0.998	0.002
M85.44 Solitary bone cyst (Hand)	0.000	0.998	0.002
M85.43 Solitary bone cyst (Forearm)	0.000	0.998	0.002
M85.42 Solitary bone cyst (Upper arm)	0.000	0.998	0.002
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.998	0.002
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.998	0.002
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.002
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
F23.8 Other acute and transient psychotic disorders	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.000	0.998	0.002
M85.3 Osteitis condensans	0.000	0.998	0.002
M85.1 Skeletal fluorosis	0.000	0.998	0.002
N99.5 Malfunction of external stoma of urinary tract	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.002	0.998	0.000
D06.0 Endocervix	0.000	0.998	0.002
S43.0 Dislocation of shoulder joint	0.000	0.998	0.002
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.998	0.002
A41.5 Septicaemia due to other Gram-negative organisms	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
F22 Persistent delusional disorders	0.002	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.002	0.998	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.998	0.002
F22.0 Delusional disorder	0.002	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
M94.3 Chondrolysis	0.000	0.998	0.002
M94.1 Relapsing polychondritis	0.000	0.998	0.002
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.998	0.002
H18.9 Disorder of cornea, unspecified	0.000	0.998	0.002
H65.2 Chronic serous otitis media	0.001	0.998	0.001
M84.3 Stress fracture, not elsewhere classified	0.000	0.998	0.002
Q83 Congenital malformations of breast	0.000	0.998	0.002
M85.46 Solitary bone cyst (Lower leg)	0.000	0.998	0.002
D32.0 Cerebral meninges	0.000	0.998	0.002
M84.9 Disorder of continuity of bone, unspecified	0.000	0.998	0.002
Y40.0 Penicillins	0.002	0.998	0.000
T95 Sequelae of burns, corrosions and frostbite	0.002	0.998	0.000
M85.22 Hyperostosis of skull-Upper arm	0.000	0.998	0.002
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.000	0.998	0.002
Y59.9 Vaccine or biological substance, unspecified	0.002	0.998	0.000
Y59.8 Other specified vaccines and biological substances	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.002	0.998	0.000
Y59.2 Protozoal vaccines	0.002	0.998	0.000
Y59.1 Rickettsial vaccines	0.002	0.998	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.002	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.002	0.998	0.000
M85.64 Other cyst of bone (Hand)	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.998	0.002
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.000	0.998	0.002
M94.98 Disorder of cartilage, unspecified (Other)	0.000	0.998	0.002
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.000	0.998	0.002
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M94.94 Disorder of cartilage, unspecified (Hand)	0.000	0.998	0.002
M94.93 Disorder of cartilage, unspecified (Forearm)	0.000	0.998	0.002
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.000	0.998	0.002
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.000	0.998	0.002
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.000	0.998	0.002
A41.2 Septicaemia due to unspecified staphylococcus	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.002	0.998	0.000
A41 Other septicaemia	0.000	0.998	0.002
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.002
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.002
Q85.8 Other phakomatoses, not elsewhere classified	0.000	0.998	0.002
Y50.9 Central nervous system stimulant, unspecified	0.002	0.998	0.000
Y50.8 Other central nervous system stimulants	0.002	0.998	0.000
Y50.1 Opioid receptor antagonists	0.002	0.998	0.000
Y50.0 Analeptics	0.002	0.998	0.000
Z99.2 Dependence on renal dialysis	0.000	0.998	0.002
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.000	0.998	0.002
D06.1 Exocervix	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.998	0.002
T83.1 Mechanical complication of other urinary devices and implants	0.000	0.998	0.002
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
H18.7 Other corneal deformities	0.000	0.998	0.002
M84.8 Other disorders of continuity of bone	0.000	0.998	0.002
M94.0 Chondrocostal junction syndrome [Tietze]	0.000	0.998	0.002
Q82.8 Other specified congenital malformations of skin	0.000	0.998	0.002
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.998	0.002
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.000	0.998	0.002
Y58.9 Other and unspecified bacterial vaccines	0.002	0.998	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.002	0.998	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.002	0.998	0.000
Y58.5 Diphtheria vaccine	0.002	0.998	0.000
Y58.4 Tetanus vaccine	0.002	0.998	0.000
Y58.3 Plague vaccine	0.002	0.998	0.000
Y58.2 Cholera vaccine	0.002	0.998	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.998	0.002
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Q85 Phakomatoses, not elsewhere classified	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
S62.21 Fracture of first metacarpal bone (open)	0.002	0.998	0.000
D06.7 Other parts of cervix	0.000	0.998	0.002
Y41.5 Antiviral drugs	0.002	0.998	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.000	0.998	0.002
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.000	0.998	0.002
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.000	0.998	0.002
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.998	0.002
M85.20 Hyperostosis of skull-Mult sites	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.998	0.002
Q83.8 Other congenital malformations of breast	0.000	0.998	0.002
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.002	0.998	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
Y58.0 BCG vaccine	0.002	0.998	0.000
F21 Schizotypal disorder	0.002	0.998	0.000
M85.29 Hyperostosis of skull-Site unspec	0.000	0.998	0.002
M85.28 Hyperostosis of skull-Other	0.000	0.998	0.002
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.998	0.002
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.998	0.002
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.998	0.002
M85.24 Hyperostosis of skull-Hand	0.000	0.998	0.002
M85.23 Hyperostosis of skull-Forearm	0.000	0.998	0.002
M85.21 Hyperostosis of skull-Shldr region	0.000	0.998	0.002
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.998	0.002
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.998	0.002
E89.3 Postprocedural hypopituitarism	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
M84.0 Malunion of fracture	0.000	0.998	0.002
M85.0 Fibrous dysplasia (monostotic)	0.000	0.998	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations