TreeWAS – Variant ID: rs2659546

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
R79.8 Other specified abnormal findings of blood chemistry	0.271	0.729	0.000
R79 Other abnormal findings of blood chemistry	0.206	0.794	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.164	0.836	0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.163	0.837	0.000
R76 Other abnormal immunological findings in serum	0.140	0.860	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.136	0.864	0.000
R74 Abnormal serum enzyme levels	0.132	0.868	0.000
R77 Other abnormalities of plasma proteins	0.132	0.868	0.000
R79.0 Abnormal level of blood mineral	0.119	0.881	0.000
R78 Findings of drugs and other substances, not normally found in blood	0.117	0.883	0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.117	0.883	0.000
R76.8 Other specified abnormal immunological findings in serum	0.115	0.885	0.000
R71 Abnormality of red blood cells	0.114	0.885	0.000
R76.0 Raised antibody titer	0.113	0.887	0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.112	0.888	0.000
R74.8 Abnormal levels of other serum enzymes	0.110	0.890	0.000
R73 Elevated blood glucose level	0.109	0.891	0.000
R77.9 Abnormality of plasma protein, unspecified	0.104	0.896	0.000
R77.8 Other specified abnormalities of plasma proteins	0.102	0.898	0.000
R76.9 Abnormal immunological finding in serum, unspecified	0.100	0.899	0.000
R76.2 False-positive serological test for syphilis	0.100	0.899	0.000
R76.1 Abnormal reaction to tuberculin test	0.100	0.899	0.000
R74.9 Abnormal level of unspecified serum enzyme	0.095	0.905	0.000
R74.0 Elevation of levels of transaminase and lactic acid dehydrogenase [LDH]	0.095	0.905	0.000
R77.2 Abnormality of alphafetoprotein	0.095	0.905	0.000
R77.1 Abnormality of globulin	0.095	0.905	0.000
R77.0 Abnormality of albumin	0.095	0.905	0.000
R78.9 Finding of unspecified substance, not normally found in blood	0.084	0.916	0.000
R78.8 Finding of other specified substances, not normally found in blood	0.084	0.916	0.000
R78.7 Finding of abnormal level of heavy metals in blood	0.084	0.916	0.000
R78.6 Finding of steroid agent in blood	0.084	0.916	0.000
R78.5 Finding of psychotropic drug in blood	0.084	0.916	0.000
R78.4 Finding of other drugs of addictive potential in blood	0.084	0.916	0.000
R78.3 Finding of hallucinogen in blood	0.084	0.916	0.000
R78.2 Finding of cocaine in blood	0.084	0.916	0.000
R78.1 Finding of opiate drug in blood	0.084	0.916	0.000
R78.0 Finding of alcohol in blood	0.084	0.916	0.000
R70.1 Abnormal plasma viscosity	0.081	0.919	0.000
R73.9 Hyperglycaemia, unspecified	0.076	0.924	0.000
R70.0 Elevated erythrocyte sedimentation rate	0.076	0.924	0.000
R73.0 Abnormal glucose tolerance test	0.071	0.928	0.000
K86.1 Other chronic pancreatitis	0.048	0.952	0.000
K86 Other diseases of pancreas	0.046	0.954	0.000
K86.8 Other specified diseases of pancreas	0.046	0.954	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.040	0.960	0.000
K86.3 Pseudocyst of pancreas	0.039	0.961	0.000
K86.9 Disease of pancreas, unspecified	0.034	0.966	0.000
K86.2 Cyst of pancreas	0.020	0.980	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.019	0.981	0.000
K82 Other diseases of gallbladder	0.018	0.982	0.000
C15.5 Lower third of oesophagus	0.000	0.982	0.018
C15.9 Oesophagus, unspecified	0.000	0.983	0.017
K81 Cholecystitis	0.016	0.984	0.000
K82.4 Cholesterolosis of gallbladder	0.016	0.984	0.000
K81.1 Chronic cholecystitis	0.016	0.984	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.984	0.016
K82.9 Disease of gallbladder, unspecified	0.016	0.984	0.000
K85 Acute pancreatitis	0.015	0.985	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.014	0.986	0.000
K82.1 Hydrops of gallbladder	0.014	0.986	0.000
K20 Oesophagitis	0.000	0.986	0.014
K85.8 Other acute pancreatitis	0.013	0.987	0.000
K82.3 Fistula of gallbladder	0.013	0.987	0.000
K82.0 Obstruction of gallbladder	0.013	0.987	0.000
K82.2 Perforation of gallbladder	0.012	0.988	0.000
C15.4 Middle third of oesophagus	0.000	0.988	0.012
K81.8 Other cholecystitis	0.012	0.988	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.989	0.011
C15.2 Abdominal part of oesophagus	0.000	0.989	0.011
C15.1 Thoracic part of oesophagus	0.000	0.989	0.011
C15.0 Cervical part of oesophagus	0.000	0.989	0.011
K85.1 Biliary acute pancreatitis	0.011	0.989	0.000
K85.3 Drug-induced acute pancreatitis	0.011	0.989	0.000
K85.2 Alcohol-induced acute pancreatitis	0.011	0.989	0.000
K85.0 Idiopathic acute pancreatitis	0.011	0.989	0.000
R25.2 Cramp and spasm	0.010	0.990	0.000
K82.8 Other specified diseases of gallbladder	0.010	0.990	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.010	0.990	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.010	0.990	0.000
K81.9 Cholecystitis, unspecified	0.010	0.990	0.000
C15.3 Upper third of oesophagus	0.000	0.990	0.010
R25 Abnormal involuntary movements	0.009	0.991	0.000
K85.9 Acute pancreatitis, unspecified	0.009	0.991	0.000
K81.0 Acute cholecystitis	0.008	0.992	0.000
R25.3 Fasciculation	0.008	0.992	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.008	0.992	0.000
R25.1 Tremor, unspecified	0.008	0.992	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.992	0.008
R25.0 Abnormal head movements	0.007	0.993	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.994	0.006
K43.9 Ventral hernia without obstruction or gangrene	0.006	0.994	0.000
M25.4 Effusion of joint	0.000	0.994	0.006
K80.0 Calculus of gallbladder with acute cholecystitis	0.006	0.994	0.000
K80 Cholelithiasis	0.005	0.995	0.000
K83 Other diseases of biliary tract	0.005	0.995	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.995	0.005
M25 Other joint disorders, not elsewhere classified	0.000	0.995	0.005
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.995	0.005
M25.5 Pain in joint	0.000	0.995	0.005
M25.50 Pain in joint (Multiple sites)	0.000	0.995	0.005
M25.47 Effusion of joint (Ankle and foot)	0.000	0.995	0.005
M25.7 Osteophyte	0.000	0.995	0.005
K80.4 Calculus of bile duct with cholecystitis	0.004	0.996	0.000
M25.8 Other specified joint disorders	0.000	0.996	0.004
M25.49 Effusion of joint (Site unspecified)	0.000	0.996	0.004
M25.48 Effusion of joint (Other)	0.000	0.996	0.004
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.996	0.004
M25.44 Effusion of joint (Hand)	0.000	0.996	0.004
M25.43 Effusion of joint (Forearm)	0.000	0.996	0.004
M25.42 Effusion of joint (Upper arm)	0.000	0.996	0.004
M25.41 Effusion of joint (Shoulder region)	0.000	0.996	0.004
M25.40 Effusion of joint (Multiple sites)	0.000	0.996	0.004
K80.3 Calculus of bile duct with cholangitis	0.004	0.996	0.000
M25.59 Pain in joint (Site unspecified)	0.000	0.996	0.004
K83.9 Disease of biliary tract, unspecified	0.004	0.996	0.000
K83.5 Biliary cyst	0.004	0.996	0.000
K83.4 Spasm of sphincter of Oddi	0.004	0.996	0.000
K83.3 Fistula of bile duct	0.004	0.996	0.000
K83.2 Perforation of bile duct	0.004	0.996	0.000
M25.53 Pain in joint (Forearm)	0.000	0.996	0.004
M25.86 Other specified joint disorders (Lower leg)	0.000	0.996	0.004
K29.4 Chronic atrophic gastritis	0.000	0.996	0.004
M25.9 Joint disorder, unspecified	0.000	0.996	0.004
M25.0 Haemarthrosis	0.000	0.996	0.004
M25.2 Flail joint	0.000	0.996	0.004
M25.1 Fistula of joint	0.000	0.996	0.004
M25.58 Pain in joint (Other)	0.000	0.996	0.004
B02.9 Zoster without complication	0.000	0.996	0.004
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.004	0.996	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.000	0.996	0.003
K80.8 Other cholelithiasis	0.003	0.996	0.000
M25.84 Other specified joint disorders (Hand)	0.000	0.996	0.003
M25.79 Osteophyte (Site unspecified)	0.000	0.996	0.003
M25.73 Osteophyte (Forearm)	0.000	0.996	0.003
M25.70 Osteophyte (Multiple sites)	0.000	0.996	0.003
M25.52 Pain in joint (Upper arm)	0.000	0.997	0.003
M25.89 Other specified joint disorders (Site unspecified)	0.000	0.997	0.003
M25.88 Other specified joint disorders (Other)	0.000	0.997	0.003
M25.83 Other specified joint disorders (Forearm)	0.000	0.997	0.003
M25.82 Other specified joint disorders (Upper arm)	0.000	0.997	0.003
M25.81 Other specified joint disorders (Shoulder region)	0.000	0.997	0.003
M25.80 Other specified joint disorders (Multiple sites)	0.000	0.997	0.003
E83.4 Disorders of magnesium metabolism	0.000	0.997	0.003
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.997	0.003
M25.74 Osteophyte (Hand)	0.000	0.997	0.003
N92.1 Excessive and frequent menstruation with irregular cycle	0.000	0.997	0.003
M25.71 Osteophyte (Shoulder region)	0.000	0.997	0.003
R27 Other lack of coordination	0.003	0.997	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.003	0.997	0.000
M25.3 Other instability of joint	0.000	0.997	0.003
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.997	0.003
M25.96 Joint disorder, unspecified (Lower leg)	0.000	0.997	0.003
M25.06 Haemarthrosis (Lower leg)	0.000	0.997	0.003
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.997	0.003
M25.98 Joint disorder, unspecified (Other)	0.000	0.997	0.003
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.997	0.003
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M25.94 Joint disorder, unspecified (Hand)	0.000	0.997	0.003
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.997	0.003
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.997	0.003
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.997	0.003
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.997	0.003
M25.09 Haemarthrosis (Site unspecified)	0.000	0.997	0.003
M25.08 Haemarthrosis (Other)	0.000	0.997	0.003
M25.07 Haemarthrosis (Ankle and foot)	0.000	0.997	0.003
M25.05 Haemarthrosis (Pelvic region and thigh)	0.000	0.997	0.003
M25.04 Haemarthrosis (Hand)	0.000	0.997	0.003
M25.03 Haemarthrosis (Forearm)	0.000	0.997	0.003
M25.02 Haemarthrosis (Upper arm)	0.000	0.997	0.003
M25.01 Haemarthrosis (Shoulder region)	0.000	0.997	0.003
M25.00 Haemarthrosis (Multiple sites)	0.000	0.997	0.003
M25.19 Fistula of joint (Site unspecified)	0.000	0.997	0.003
M25.18 Fistula of joint (Other)	0.000	0.997	0.003
M25.17 Fistula of joint (Ankle and foot)	0.000	0.997	0.003
M25.16 Fistula of joint (Lower leg)	0.000	0.997	0.003
M25.15 Fistula of joint (Pelvic region and thigh)	0.000	0.997	0.003
M25.14 Fistula of joint (Hand)	0.000	0.997	0.003
M25.13 Fistula of joint (Forearm)	0.000	0.997	0.003
M25.12 Fistula of joint (Upper arm)	0.000	0.997	0.003
M25.11 Fistula of joint (Shoulder region)	0.000	0.997	0.003
M25.10 Fistula of joint (Multiple sites)	0.000	0.997	0.003
M25.29 Flail joint (Site unspecified)	0.000	0.997	0.003
M25.28 Flail joint (Other)	0.000	0.997	0.003
M25.27 Flail joint (Ankle and foot)	0.000	0.997	0.003
M25.26 Flail joint (Lower leg)	0.000	0.997	0.003
M25.25 Flail joint (Pelvic region and thigh)	0.000	0.997	0.003
M25.24 Flail joint (Hand)	0.000	0.997	0.003
M25.23 Flail joint (Forearm)	0.000	0.997	0.003
M25.22 Flail joint (Upper arm)	0.000	0.997	0.003
M25.21 Flail joint (Shoulder region)	0.000	0.997	0.003
M25.20 Flail joint (Multiple sites)	0.000	0.997	0.003
M25.78 Osteophyte (Other)	0.000	0.997	0.003
Z35.5 Supervision of elderly primigravida	0.003	0.997	0.000
R27.8 Other and unspecified lack of coordination	0.003	0.997	0.000
K83.1 Obstruction of bile duct	0.003	0.997	0.000
M25.72 Osteophyte (Upper arm)	0.000	0.997	0.003
R27.0 Ataxia, unspecified	0.003	0.997	0.000
R80 Isolated proteinuria	0.003	0.997	0.000
M25.54 Pain in joint (Hand)	0.000	0.997	0.002
M25.39 Other instability of joint (Site unspecified)	0.000	0.997	0.002
M25.38 Other instability of joint (Other)	0.000	0.997	0.002
M25.36 Other instability of joint (Lower leg)	0.000	0.997	0.002
M25.35 Other instability of joint (Pelvic region and thigh)	0.000	0.997	0.002
M25.34 Other instability of joint (Hand)	0.000	0.997	0.002
M25.33 Other instability of joint (Forearm)	0.000	0.997	0.002
M25.32 Other instability of joint (Upper arm)	0.000	0.997	0.002
M25.30 Other instability of joint (Multiple sites)	0.000	0.997	0.002
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.997	0.002
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.000	0.997	0.002
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.997	0.002
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.997	0.002
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.000	0.997	0.002
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.997	0.002
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.997	0.002
A49.0 Staphylococcal infection, unspecified	0.000	0.997	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.997	0.002
I21.9 Acute myocardial infarction, unspecified	0.003	0.997	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
M25.31 Other instability of joint (Shoulder region)	0.000	0.998	0.002
M25.57 Pain in joint (Ankle and foot)	0.000	0.998	0.002
K83.0 Cholangitis	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
E83.5 Disorders of calcium metabolism	0.000	0.998	0.002
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.998	0.002
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum	0.002	0.998	0.000
R81 Glycosuria	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.000	0.998	0.002
K29.3 Chronic superficial gastritis	0.000	0.998	0.002
E53.8 Deficiency of other specified B group vitamins	0.002	0.998	0.000
K43 Ventral hernia	0.002	0.998	0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.002	0.998	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.002	0.998	0.000
Z53.8 Procedure not carried out for other reasons	0.000	0.998	0.002
K83.8 Other specified diseases of biliary tract	0.002	0.998	0.000
N32.0 Bladder-neck obstruction	0.000	0.998	0.002
M25.37 Other instability of joint (Ankle and foot)	0.000	0.998	0.002
M25.51 Pain in joint (Shoulder region)	0.000	0.998	0.002
K29.8 Duodenitis	0.000	0.998	0.002
E83 Disorders of mineral metabolism	0.000	0.998	0.002
B02 Zoster [herpes zoster]	0.000	0.998	0.002
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters	0.000	0.998	0.002
I67.8 Other specified cerebrovascular diseases	0.000	0.998	0.002
E83.3 Disorders of phosphorus metabolism	0.000	0.998	0.002
K29 Gastritis and duodenitis	0.000	0.998	0.002
K43.7 Other and unspecified ventral hernia with gangrene	0.002	0.998	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.002	0.998	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.002	0.998	0.000
K43.4 Parastomal hernia with gangrene	0.002	0.998	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.002	0.998	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.002	0.998	0.000
K43.1 Ventral hernia with gangrene	0.002	0.998	0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
A49 Bacterial infection of unspecified site	0.000	0.998	0.002
A49.8 Other bacterial infections of unspecified site	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.000	0.998	0.002
K29.0 Acute haemorrhagic gastritis	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.002	0.998	0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.002	0.998	0.000
K29.6 Other gastritis	0.000	0.998	0.002
E61 Deficiency of other nutrient elements	0.002	0.998	0.000
A49.9 Bacterial infection, unspecified	0.000	0.998	0.002
B02.8 Zoster with other complications	0.000	0.998	0.002
B02.7 Disseminated zoster	0.000	0.998	0.002
B02.2 Zoster with other nervous system involvement	0.000	0.998	0.002
B02.1 Zoster meningitis	0.000	0.998	0.002
B02.0 Zoster encephalitis	0.000	0.998	0.002
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.998	0.002
E83.8 Other disorders of mineral metabolism	0.000	0.998	0.002
E83.2 Disorders of zinc metabolism	0.000	0.998	0.002
E83.0 Disorders of copper metabolism	0.000	0.998	0.002
R93 Abnormal findings on diagnostic imaging of other body structures	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.998	0.002
R29.4 Clicking hip	0.002	0.998	0.000
R29.3 Abnormal posture	0.002	0.998	0.000
R29.2 Abnormal reflex	0.002	0.998	0.000
R29.1 Meningismus	0.002	0.998	0.000
R29.0 Tetany	0.002	0.998	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.002	0.998	0.000
E53 Deficiency of other B group vitamins	0.002	0.998	0.000
B02.3 Zoster ocular disease	0.000	0.998	0.002
H93.1 Tinnitus	0.000	0.998	0.002
K04.5 Chronic apical periodontitis	0.002	0.998	0.000
A49.1 Streptococcal infection, unspecified	0.000	0.998	0.002
R26 Abnormalities of gait and mobility	0.001	0.998	0.000
K29.9 Gastroduodenitis, unspecified	0.000	0.998	0.001
K29.2 Alcoholic gastritis	0.000	0.998	0.002
R93.4 Abnormal findings on diagnostic imaging of urinary organs	0.002	0.998	0.000
A49.3 Mycoplasma infection, unspecified	0.000	0.998	0.001
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.998	0.001
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.001	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
R82 Other abnormal findings in urine	0.001	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.001	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.001	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.001	0.998	0.000
E61.6 Vanadium deficiency	0.001	0.998	0.000
E61.5 Molybdenum deficiency	0.001	0.998	0.000
E61.4 Chromium deficiency	0.001	0.998	0.000
E61.3 Manganese deficiency	0.001	0.998	0.000
E61.2 Magnesium deficiency	0.001	0.998	0.000
E61.0 Copper deficiency	0.001	0.998	0.000
I78.1 Naevus, nonneoplastic	0.000	0.998	0.002
K08.8 Other specified disorders of teeth and supporting structures	0.002	0.998	0.000
R93.6 Abnormal findings on diagnostic imaging of limbs	0.001	0.998	0.000
Z00.0 General medical examination	0.002	0.998	0.000
Z48.0 Attention to surgical dressings and sutures	0.002	0.998	0.000
S00.9 Superficial injury of head, part unspecified	0.001	0.998	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.001	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.001	0.998	0.000
R95-R99 Ill-defined and unknown causes of mortality	0.001	0.998	0.000
E53.9 Vitamin B deficiency, unspecified	0.001	0.999	0.000
E53.1 Pyridoxine deficiency	0.001	0.999	0.000
E53.0 Riboflavin deficiency	0.001	0.999	0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system	0.001	0.999	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
R26.1 Paralytic gait	0.001	0.999	0.000
S06.4 Epidural haemorrhage	0.001	0.999	0.000
S02.10 Fracture of base of skull (closed)	0.001	0.999	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.001	0.999	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.001	0.999	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.001	0.999	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.999	0.001
I60.9 Subarachnoid haemorrhage, unspecified	0.001	0.999	0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.001	0.999	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.999	0.001
R82.6 Abnormal urine levels of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R82.5 Elevated urine levels of drugs, medicaments and biological substances	0.001	0.999	0.000
R82.4 Acetonuria	0.001	0.999	0.000
R82.3 Haemoglobinuria	0.001	0.999	0.000
R82.2 Biliuria	0.001	0.999	0.000
R82.1 Myoglobinuria	0.001	0.999	0.000
R82.0 Chyluria	0.001	0.999	0.000
M77.47 Metatarsalgia-Ankle/Foot	0.000	0.999	0.001
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.999	0.001
N93.0 Postcoital and contact bleeding	0.001	0.999	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.001	0.999	0.000
R47-R49 Symptoms and signs involving speech and voice	0.001	0.999	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.999	0.001
R82.7 Abnormal findings on microbiological examination of urine	0.001	0.999	0.000
Z98.1 Arthrodesis status	0.000	0.999	0.001
R96 Other sudden death, cause unknown	0.001	0.999	0.000
R95 Sudden infant death syndrome	0.001	0.999	0.000
R99 Other ill-defined and unspecified causes of mortality	0.001	0.999	0.000
R98 Unattended death	0.001	0.999	0.000
R26.3 Immobility	0.001	0.999	0.000
R26.0 Ataxic gait	0.001	0.999	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.001	0.999	0.000
L57.4 Cutis laxa senilis	0.001	0.999	0.000
H60 Otitis externa	0.000	0.999	0.001
R47 Speech disturbances, not elsewhere classified	0.001	0.999	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.999	0.000
Z35 Supervision of high-risk pregnancy	0.001	0.999	0.000
L29.0 Pruritus ani	0.000	0.999	0.001
R82.8 Abnormal findings on cytological and histological examination of urine	0.001	0.999	0.001
R93.8 Abnormal findings on diagnostic imaging of other specified body structures	0.001	0.999	0.000
T18.1 Foreign body in oesophagus	0.000	0.999	0.001
S06.20 Diffuse brain injury (without open intracranial wound)	0.001	0.999	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.001	0.999	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.001	0.999	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.001	0.999	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.001	0.999	0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters	0.000	0.999	0.001
H60.1 Cellulitis of external ear	0.000	0.999	0.001
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.999	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.001	0.999	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.001	0.999	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.001	0.999	0.000
R84.5 Abnormal microbiological findings	0.001	0.999	0.000
R95.9 Sudden infant death syndrome without mention of autopsy	0.001	0.999	0.000
R95.0 Sudden infant death syndrome with mention of autopsy	0.001	0.999	0.000
R96.1 Death occurring less than 24 hours from onset of symptoms, not otherwise explained	0.001	0.999	0.000
R96.0 Instantaneous death	0.001	0.999	0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.001	0.999	0.000
H53.8 Other visual disturbances	0.001	0.999	0.000
H60.8 Other otitis externa	0.000	0.999	0.001
H60.5 Acute otitis externa, non-infective	0.000	0.999	0.001
H60.4 Cholesteatoma of external ear	0.000	0.999	0.001
H60.2 Malignant otitis externa	0.000	0.999	0.001
H60.0 Abscess of external ear	0.000	0.999	0.001
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.001	0.999	0.000
S06.2 Diffuse brain injury	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.001	0.999	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.001	0.999	0.000
Z35.9 Supervision of high-risk pregnancy, unspecified	0.001	0.999	0.000
Z35.8 Supervision of other high-risk pregnancies	0.001	0.999	0.000
Z35.7 Supervision of high-risk pregnancy due to social problems	0.001	0.999	0.000
Z35.6 Supervision of very young primigravida	0.001	0.999	0.000
Z35.4 Supervision of pregnancy with grand multiparity	0.001	0.999	0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care	0.001	0.999	0.000
Z35.0 Supervision of pregnancy with history of infertility	0.001	0.999	0.000
E50-E64 Other nutritional deficiencies	0.001	0.999	0.000
N32.3 Diverticulum of bladder	0.000	0.999	0.001
R29.6 Tendency to fall, not elsewhere classified	0.001	0.999	0.000
T40.2 Other opioids	0.001	0.999	0.000
S06 Intracranial injury	0.001	0.999	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.999	0.000
R84.9 Unspecified abnormal finding	0.001	0.999	0.000
R84.8 Other abnormal findings	0.001	0.999	0.000
R84.7 Abnormal histological findings	0.001	0.999	0.000
R84.6 Abnormal cytological findings	0.001	0.999	0.000
R84.4 Abnormal immunological findings	0.001	0.999	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R84.1 Abnormal level of hormones	0.001	0.999	0.000
R84.0 Abnormal level of enzymes	0.001	0.999	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.001	0.999	0.000
R89 Abnormal findings in specimens from other organs, systems and tissues	0.001	0.999	0.000
R83 Abnormal findings in cerebrospinal fluid	0.001	0.999	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.001	0.999	0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.999	0.001
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.999	0.001
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.999	0.001
R48.8 Other and unspecified symbolic dysfunctions	0.001	0.999	0.000
R48.2 Apraxia	0.001	0.999	0.000
R48.1 Agnosia	0.001	0.999	0.000
R48.0 Dyslexia and alexia	0.001	0.999	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.001	0.999	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.001	0.999	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.001	0.999	0.000
C22.1 Intrahepatic bile duct carcinoma	0.000	0.999	0.001
H80.9 Otosclerosis, unspecified	0.000	0.999	0.001
N64.1 Fat necrosis of breast	0.000	0.999	0.001
S02.1 Fracture of base of skull	0.001	0.999	0.000
H60.3 Other infective otitis externa	0.000	0.999	0.001
R59.0 Localised enlarged lymph nodes	0.000	0.999	0.001
S00.8 Superficial injury of other parts of head	0.001	0.999	0.000
S01.1 Open wound of eyelid and periocular area	0.001	0.999	0.000
S06.9 Intracranial injury, unspecified	0.001	0.999	0.000
S06.7 Intracranial injury with prolonged coma	0.001	0.999	0.000
S06.1 Traumatic cerebral oedema	0.001	0.999	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.001	0.999	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.001	0.999	0.000
E63 Other nutritional deficiencies	0.001	0.999	0.000
E56 Other vitamin deficiencies	0.001	0.999	0.000
E51 Thiamine deficiency	0.001	0.999	0.000
E50 Vitamin A deficiency	0.001	0.999	0.000
E60 Dietary zinc deficiency	0.001	0.999	0.000
E59 Dietary selenium deficiency	0.001	0.999	0.000
E58 Dietary calcium deficiency	0.001	0.999	0.000
E54 Ascorbic acid deficiency	0.001	0.999	0.000
E52 Niacin deficiency [pellagra]	0.001	0.999	0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.001	0.999	0.000
H92.0 Otalgia	0.000	0.999	0.001
R83.9 Unspecified abnormal finding	0.001	0.999	0.000
R83.8 Other abnormal findings	0.001	0.999	0.000
R83.7 Abnormal histological findings	0.001	0.999	0.000
R83.6 Abnormal cytological findings	0.001	0.999	0.000
R83.5 Abnormal microbiological findings	0.001	0.999	0.000
R83.4 Abnormal immunological findings	0.001	0.999	0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R83.1 Abnormal level of hormones	0.001	0.999	0.000
R83.0 Abnormal level of enzymes	0.001	0.999	0.000
R89.9 Unspecified abnormal finding	0.001	0.999	0.000
R89.8 Other abnormal findings	0.001	0.999	0.000
R89.7 Abnormal histological findings	0.001	0.999	0.000
R89.6 Abnormal cytological findings	0.001	0.999	0.000
R89.5 Abnormal microbiological findings	0.001	0.999	0.000
R89.4 Abnormal immunological findings	0.001	0.999	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.001	0.999	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.001	0.999	0.000
R89.1 Abnormal level of hormones	0.001	0.999	0.000
R89.0 Abnormal level of enzymes	0.001	0.999	0.000
S01.5 Open wound of lip and oral cavity	0.001	0.999	0.000
S06.8 Other intracranial injuries	0.001	0.999	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.001	0.999	0.000
C16.0 Cardia	0.000	0.999	0.001
C77.9 Lymph node, unspecified	0.000	0.999	0.001
M20.6 Acquired deformity of toe(s), unspecified	0.000	0.999	0.001
S01.9 Open wound of head, part unspecified	0.001	0.999	0.000
R92 Abnormal findings on diagnostic imaging of breast	0.001	0.999	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.001	0.999	0.000
S02.11 Fracture of base of skull (open)	0.001	0.999	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.001	0.999	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.001	0.999	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.001	0.999	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.001	0.999	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.001	0.999	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.001	0.999	0.000
C22.9 Liver, unspecified	0.000	0.999	0.001
E50.9 Vitamin A deficiency, unspecified	0.001	0.999	0.000
E50.8 Other manifestations of vitamin A deficiency	0.001	0.999	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.001	0.999	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.001	0.999	0.000
E50.5 Vitamin A deficiency with night blindness	0.001	0.999	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.001	0.999	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.001	0.999	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.001	0.999	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.001	0.999	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.001	0.999	0.000
E51.9 Thiamine deficiency, unspecified	0.001	0.999	0.000
E51.8 Other manifestations of thiamine deficiency	0.001	0.999	0.000
E51.2 Wernicke's encephalopathy	0.001	0.999	0.000
E51.1 Beriberi	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations