TreeWAS – Variant ID: rs2688482

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I35.0 Aortic (valve) stenosis	0.000	0.901	0.099
I35 Nonrheumatic aortic valve disorders	0.000	0.904	0.096
I35.8 Other aortic valve disorders	0.000	0.908	0.092
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.918	0.082
I35.9 Aortic valve disorder, unspecified	0.000	0.920	0.080
I35.1 Aortic (valve) insufficiency	0.000	0.920	0.080
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.071	0.929	0.000
M89.9 Disorder of bone, unspecified	0.067	0.933	0.000
M89 Other disorders of bone	0.060	0.940	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.055	0.945	0.000
M89.98 Disorder of bone, unspecified (Other)	0.054	0.946	0.000
M89.0 Algoneurodystrophy	0.053	0.947	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.052	0.948	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.052	0.948	0.000
M89.3 Hypertrophy of bone	0.050	0.950	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.049	0.951	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.048	0.952	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.047	0.953	0.000
M88 Paget's disease of bone [osteitis deformans]	0.047	0.953	0.000
M86-M90 Other osteopathies	0.047	0.953	0.000
M88.9 Paget's disease of bone, unspecified	0.046	0.954	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.045	0.954	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.045	0.955	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.045	0.955	0.000
M89.5 Osteolysis	0.045	0.955	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.044	0.956	0.000
M89.6 Osteopathy after poliomyelitis	0.043	0.957	0.000
M89.2 Other disorders of bone development and growth	0.043	0.957	0.000
M89.1 Epiphyseal arrest	0.043	0.957	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.041	0.959	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.040	0.959	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.040	0.960	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.040	0.960	0.000
M88.8 Paget's disease of other bones	0.040	0.960	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.039	0.961	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.039	0.961	0.000
M89.08 Algoneurodystrophy (Other)	0.038	0.962	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.038	0.962	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.038	0.962	0.000
M89.03 Algoneurodystrophy (Forearm)	0.038	0.962	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.037	0.963	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.036	0.964	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.036	0.964	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.036	0.964	0.000
M89.34 Hypertrophy of bone (Hand)	0.036	0.964	0.000
M89.33 Hypertrophy of bone (Forearm)	0.036	0.964	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.036	0.964	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.036	0.964	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.036	0.964	0.000
M90 Osteopathies in diseases classified elsewhere	0.036	0.964	0.000
M88.0 Paget's disease of skull	0.035	0.965	0.000
M87 Osteonecrosis	0.035	0.965	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.034	0.966	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.034	0.966	0.000
M89.8 Other specified disorders of bone	0.033	0.967	0.000
S81.0 Open wound of knee	0.033	0.967	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.033	0.967	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.033	0.967	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.033	0.967	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.033	0.967	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.033	0.967	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.033	0.967	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.033	0.967	0.000
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.033	0.967	0.000
M89.38 Hypertrophy of bone (Other)	0.033	0.967	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.032	0.967	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.032	0.967	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.032	0.967	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.032	0.967	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.032	0.967	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.032	0.967	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.032	0.967	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.032	0.967	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.032	0.967	0.000
M89.59 Osteolysis (Site unspecified)	0.032	0.968	0.000
M89.58 Osteolysis (Other)	0.032	0.968	0.000
M89.57 Osteolysis (Ankle and foot)	0.032	0.968	0.000
M89.56 Osteolysis (Lower leg)	0.032	0.968	0.000
M89.54 Osteolysis (Hand)	0.032	0.968	0.000
M89.53 Osteolysis (Forearm)	0.032	0.968	0.000
M89.52 Osteolysis (Upper arm)	0.032	0.968	0.000
M89.51 Osteolysis (Shoulder region)	0.032	0.968	0.000
M89.50 Osteolysis (Multiple sites)	0.032	0.968	0.000
M89.04 Algoneurodystrophy (Hand)	0.031	0.969	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.031	0.969	0.000
M89.18 Epiphyseal arrest (Other)	0.031	0.969	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.031	0.969	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.031	0.969	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.031	0.969	0.000
M89.14 Epiphyseal arrest (Hand)	0.031	0.969	0.000
M89.13 Epiphyseal arrest (Forearm)	0.031	0.969	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.031	0.969	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.031	0.969	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.031	0.969	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.031	0.969	0.000
M89.28 Other disorders of bone development and growth (Other)	0.031	0.969	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.031	0.969	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.031	0.969	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.031	0.969	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.031	0.969	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.031	0.969	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.031	0.969	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.031	0.969	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.031	0.969	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.031	0.969	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.031	0.969	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.031	0.969	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.031	0.969	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.031	0.969	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.031	0.969	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.031	0.969	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.031	0.969	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.031	0.969	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.031	0.969	0.000
M88.88 Paget's disease of other bones (Other)	0.031	0.969	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.031	0.969	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.030	0.970	0.000
M87.8 Other osteonecrosis	0.030	0.970	0.000
M90.1 Periostitis in other infectious diseases classified elsewhere	0.029	0.971	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.029	0.971	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.029	0.971	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.029	0.971	0.000
M88.84 Paget's disease of other bones (Hand)	0.029	0.971	0.000
M88.83 Paget's disease of other bones (Forearm)	0.029	0.971	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.029	0.971	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.029	0.971	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.029	0.971	0.000
M87.3 Other secondary osteonecrosis	0.028	0.972	0.000
M87.2 Osteonecrosis due to previous trauma	0.027	0.973	0.000
M90.7 Fracture of bone in neoplastic disease	0.027	0.973	0.000
M88.00 Paget's disease of skull-Mult sites	0.027	0.973	0.000
M87.1 Osteonecrosis due to drugs	0.026	0.974	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.026	0.974	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.026	0.974	0.000
M90.3 Osteonecrosis in caisson disease	0.026	0.974	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.026	0.974	0.000
M90.0 Tuberculosis of bone	0.026	0.974	0.000
M89.88 Other specified disorders of bone (Other)	0.025	0.974	0.000
M88.09 Paget's disease of skull-Site unspec	0.025	0.975	0.000
M88.08 Paget's disease of skull-Other	0.025	0.975	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.025	0.975	0.000
M88.06 Paget's disease of skull-Lower Leg	0.025	0.975	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.025	0.975	0.000
M88.04 Paget's disease of skull-Hand	0.025	0.975	0.000
M88.03 Paget's disease of skull-Forearm	0.025	0.975	0.000
M88.02 Paget's disease of skull-Upper arm	0.025	0.975	0.000
M88.01 Paget's disease of skull-Shldr region	0.025	0.975	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.025	0.975	0.000
M90.6 Osteitis deformans in neoplastic disease	0.025	0.975	0.000
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.024	0.976	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.024	0.976	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.024	0.976	0.000
M90.10 Periostitis in other infectious diseases classified elsewhere (Multiple sites)	0.024	0.976	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.023	0.976	0.000
M87.86 Other osteonecrosis (Lower leg)	0.023	0.976	0.000
M87.0 Idiopathic aseptic necrosis of bone	0.023	0.977	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.023	0.977	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.022	0.978	0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)	0.022	0.978	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.022	0.978	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.022	0.978	0.000
M87.89 Other osteonecrosis (Site unspecified)	0.021	0.979	0.000
M87.88 Other osteonecrosis (Other)	0.021	0.979	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.021	0.979	0.000
M87.84 Other osteonecrosis (Hand)	0.021	0.979	0.000
M87.83 Other osteonecrosis (Forearm)	0.021	0.979	0.000
M87.82 Other osteonecrosis (Upper arm)	0.021	0.979	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.021	0.979	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.021	0.979	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.021	0.979	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.021	0.979	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.021	0.979	0.000
M90.19 Periostitis in other infectious diseases classified elsewhere (Site unspecified)	0.021	0.979	0.000
M90.18 Periostitis in other infectious diseases classified elsewhere (Other)	0.021	0.979	0.000
M90.17 Periostitis in other infectious diseases classified elsewhere (Ankle and foot)	0.021	0.979	0.000
M90.16 Periostitis in other infectious diseases classified elsewhere (Lower leg)	0.021	0.979	0.000
M90.15 Periostitis in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.021	0.979	0.000
M90.14 Periostitis in other infectious diseases classified elsewhere (Hand)	0.021	0.979	0.000
M90.13 Periostitis in other infectious diseases classified elsewhere (Forearm)	0.021	0.979	0.000
M90.12 Periostitis in other infectious diseases classified elsewhere (Upper arm)	0.021	0.979	0.000
M90.11 Periostitis in other infectious diseases classified elsewhere (Shoulder region)	0.021	0.979	0.000
M89.83 Other specified disorders of bone (Forearm)	0.020	0.979	0.000
M87.24 Osteonecrosis due to previous trauma (Hand)	0.020	0.980	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.020	0.980	0.000
M87.38 Other secondary osteonecrosis (Other)	0.020	0.980	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.020	0.980	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.020	0.980	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.020	0.980	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.020	0.980	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.020	0.980	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.020	0.980	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.020	0.980	0.000
M89.84 Other specified disorders of bone (Hand)	0.020	0.980	0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)	0.020	0.980	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.020	0.980	0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)	0.020	0.980	0.000
M87.28 Osteonecrosis due to previous trauma (Other)	0.020	0.980	0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)	0.020	0.980	0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)	0.020	0.980	0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)	0.020	0.980	0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)	0.020	0.980	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.020	0.980	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.020	0.980	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.020	0.980	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.020	0.980	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.020	0.980	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.019	0.981	0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk	0.019	0.981	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.019	0.981	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.019	0.981	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.019	0.981	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.019	0.981	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.019	0.981	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.019	0.981	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.019	0.981	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.019	0.981	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.019	0.981	0.000
M90.09 Tuberculosis of bone (Site unspecified)	0.019	0.981	0.000
M90.08 Tuberculosis of bone (Other)	0.019	0.981	0.000
M90.07 Tuberculosis of bone (Ankle and foot)	0.019	0.981	0.000
M90.06 Tuberculosis of bone (Lower leg)	0.019	0.981	0.000
M90.05 Tuberculosis of bone (Pelvic region and thigh)	0.019	0.981	0.000
M90.04 Tuberculosis of bone (Hand)	0.019	0.981	0.000
M90.03 Tuberculosis of bone (Forearm)	0.019	0.981	0.000
M90.02 Tuberculosis of bone (Upper arm)	0.019	0.981	0.000
M90.01 Tuberculosis of bone (Shoulder region)	0.019	0.981	0.000
M90.00 Tuberculosis of bone (Multiple sites)	0.019	0.981	0.000
M90.29 Osteopathy in other infectious diseases classified elsewhere (Site unspecified)	0.019	0.981	0.000
M90.28 Osteopathy in other infectious diseases classified elsewhere (Other)	0.019	0.981	0.000
M90.27 Osteopathy in other infectious diseases classified elsewhere (Ankle and foot)	0.019	0.981	0.000
M90.26 Osteopathy in other infectious diseases classified elsewhere (Lower leg)	0.019	0.981	0.000
M90.25 Osteopathy in other infectious diseases classified elsewhere (Pelvic region and thigh)	0.019	0.981	0.000
M90.24 Osteopathy in other infectious diseases classified elsewhere (Hand)	0.019	0.981	0.000
M90.23 Osteopathy in other infectious diseases classified elsewhere (Forearm)	0.019	0.981	0.000
M90.22 Osteopathy in other infectious diseases classified elsewhere (Upper arm)	0.019	0.981	0.000
M90.21 Osteopathy in other infectious diseases classified elsewhere (Shoulder region)	0.019	0.981	0.000
M90.20 Osteopathy in other infectious diseases classified elsewhere (Multiple sites)	0.019	0.981	0.000
M90.39 Osteonecrosis in caisson disease (Site unspecified)	0.019	0.981	0.000
M90.38 Osteonecrosis in caisson disease (Other)	0.019	0.981	0.000
M90.37 Osteonecrosis in caisson disease (Ankle and foot)	0.019	0.981	0.000
M90.36 Osteonecrosis in caisson disease (Lower leg)	0.019	0.981	0.000
M90.35 Osteonecrosis in caisson disease (Pelvic region and thigh)	0.019	0.981	0.000
M90.34 Osteonecrosis in caisson disease (Hand)	0.019	0.981	0.000
M90.33 Osteonecrosis in caisson disease (Forearm)	0.019	0.981	0.000
M90.32 Osteonecrosis in caisson disease (Upper arm)	0.019	0.981	0.000
M90.31 Osteonecrosis in caisson disease (Shoulder region)	0.019	0.981	0.000
M90.30 Osteonecrosis in caisson disease (Multiple sites)	0.019	0.981	0.000
M90.49 Osteonecrosis due to haemoglobinopathy (Site unspecified)	0.019	0.981	0.000
M90.48 Osteonecrosis due to haemoglobinopathy (Other)	0.019	0.981	0.000
M90.47 Osteonecrosis due to haemoglobinopathy (Ankle and foot)	0.019	0.981	0.000
M90.46 Osteonecrosis due to haemoglobinopathy (Lower leg)	0.019	0.981	0.000
M90.45 Osteonecrosis due to haemoglobinopathy (Pelvic region and thigh)	0.019	0.981	0.000
M90.44 Osteonecrosis due to haemoglobinopathy (Hand)	0.019	0.981	0.000
M90.43 Osteonecrosis due to haemoglobinopathy (Forearm)	0.019	0.981	0.000
M90.42 Osteonecrosis due to haemoglobinopathy (Upper arm)	0.019	0.981	0.000
M90.41 Osteonecrosis due to haemoglobinopathy (Shoulder region)	0.019	0.981	0.000
M90.40 Osteonecrosis due to haemoglobinopathy (Multiple sites)	0.019	0.981	0.000
M90.59 Osteonecrosis in other diseases classified elsewhere (Site unspecified)	0.019	0.981	0.000
M90.58 Osteonecrosis in other diseases classified elsewhere (Other)	0.019	0.981	0.000
M90.57 Osteonecrosis in other diseases classified elsewhere (Ankle and foot)	0.019	0.981	0.000
M90.56 Osteonecrosis in other diseases classified elsewhere (Lower leg)	0.019	0.981	0.000
M90.55 Osteonecrosis in other diseases classified elsewhere (Pelvic region and thigh)	0.019	0.981	0.000
M90.54 Osteonecrosis in other diseases classified elsewhere (Hand)	0.019	0.981	0.000
M90.53 Osteonecrosis in other diseases classified elsewhere (Forearm)	0.019	0.981	0.000
M90.52 Osteonecrosis in other diseases classified elsewhere (Upper arm)	0.019	0.981	0.000
M90.51 Osteonecrosis in other diseases classified elsewhere (Shoulder region)	0.019	0.981	0.000
M90.50 Osteonecrosis in other diseases classified elsewhere (Multiple sites)	0.019	0.981	0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.019	0.981	0.000
M90.80 Osteopathy in other diseases classified elsewhere (Multiple sites)	0.019	0.981	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.018	0.982	0.000
M90.89 Osteopathy in other diseases classified elsewhere (Site unspecified)	0.018	0.982	0.000
M90.88 Osteopathy in other diseases classified elsewhere (Other)	0.018	0.982	0.000
M90.87 Osteopathy in other diseases classified elsewhere (Ankle and foot)	0.018	0.982	0.000
M90.86 Osteopathy in other diseases classified elsewhere (Lower leg)	0.018	0.982	0.000
M90.85 Osteopathy in other diseases classified elsewhere (Pelvic region and thigh)	0.018	0.982	0.000
M90.83 Osteopathy in other diseases classified elsewhere (Forearm)	0.018	0.982	0.000
M90.82 Osteopathy in other diseases classified elsewhere (Upper arm)	0.018	0.982	0.000
M90.81 Osteopathy in other diseases classified elsewhere (Shoulder region)	0.018	0.982	0.000
M90.69 Osteitis deformans in neoplastic disease (Site unspecified)	0.018	0.982	0.000
M90.68 Osteitis deformans in neoplastic disease (Other)	0.018	0.982	0.000
M90.67 Osteitis deformans in neoplastic disease (Ankle and foot)	0.018	0.982	0.000
M90.66 Osteitis deformans in neoplastic disease (Lower leg)	0.018	0.982	0.000
M90.65 Osteitis deformans in neoplastic disease (Pelvic region and thigh)	0.018	0.982	0.000
M90.64 Osteitis deformans in neoplastic disease (Hand)	0.018	0.982	0.000
M90.63 Osteitis deformans in neoplastic disease (Forearm)	0.018	0.982	0.000
M90.62 Osteitis deformans in neoplastic disease (Upper arm)	0.018	0.982	0.000
M90.60 Osteitis deformans in neoplastic disease (Multiple sites)	0.018	0.982	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.018	0.982	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.017	0.983	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.017	0.983	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.017	0.983	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.017	0.983	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.017	0.983	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.017	0.983	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.017	0.983	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.017	0.983	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.017	0.983	0.000
S81 Open wound of lower leg	0.017	0.983	0.000
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)	0.017	0.983	0.000
M86 Osteomyelitis	0.016	0.983	0.001
T42.1 Iminostilbenes	0.017	0.983	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.016	0.984	0.000
T42.0 Hydantoin derivatives	0.016	0.984	0.000
M90.84 Osteopathy in other diseases classified elsewhere (Hand)	0.016	0.984	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.016	0.984	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.016	0.984	0.000
S81.8 Open wound of other parts of lower leg	0.015	0.985	0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)	0.015	0.985	0.000
T42.3 Barbiturates	0.015	0.985	0.000
T42.4 Benzodiazepines	0.015	0.985	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.014	0.985	0.000
T42.2 Succinimides and oxazolidinediones	0.014	0.985	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.014	0.986	0.000
T39.1 4-Aminophenol derivatives	0.014	0.986	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.014	0.986	0.000
S81.7 Multiple open wounds of lower leg	0.013	0.986	0.000
M87.9 Osteonecrosis, unspecified	0.013	0.987	0.000
M86.4 Chronic osteomyelitis with draining sinus	0.012	0.987	0.000
M86.5 Other chronic haematogenous osteomyelitis	0.012	0.988	0.001
M86.3 Chronic multifocal osteomyelitis	0.012	0.988	0.001
M86.2 Subacute osteomyelitis	0.012	0.988	0.001
M86.0 Acute haematogenous osteomyelitis	0.012	0.988	0.001
M86.1 Other acute osteomyelitis	0.011	0.988	0.001
M86.8 Other osteomyelitis	0.011	0.988	0.001
T36-T50 Poisoning by drugs, medicaments and biological substances	0.012	0.988	0.000
T39.4 Antirheumatics, not elsewhere classified	0.010	0.989	0.000
T39.2 Pyrazolone derivatives	0.010	0.989	0.000
T39.0 Salicylates	0.010	0.990	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.010	0.990	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.010	0.990	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.010	0.990	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.010	0.990	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.010	0.990	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.010	0.990	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.010	0.990	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.010	0.990	0.000
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.009	0.990	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.009	0.990	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.009	0.990	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.009	0.990	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.009	0.990	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.009	0.990	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.009	0.990	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.009	0.990	0.000
K12.1 Other forms of stomatitis	0.010	0.990	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.009	0.991	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.009	0.991	0.000
C25.9 Pancreas, unspecified	0.000	0.991	0.009
T43.3 Phenothiazine antipsychotics and neuroleptics	0.009	0.991	0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.009	0.991	0.001
M86.08 Acute haematogenous osteomyelitis (Other)	0.009	0.991	0.001
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.009	0.991	0.001
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.009	0.991	0.001
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.009	0.991	0.001
M86.04 Acute haematogenous osteomyelitis (Hand)	0.009	0.991	0.001
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.009	0.991	0.001
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.009	0.991	0.001
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.009	0.991	0.001
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.009	0.991	0.001
M86.29 Subacute osteomyelitis (Site unspecified)	0.009	0.991	0.001
M86.28 Subacute osteomyelitis (Other)	0.009	0.991	0.001
M86.27 Subacute osteomyelitis (Ankle and foot)	0.009	0.991	0.001
M86.26 Subacute osteomyelitis (Lower leg)	0.009	0.991	0.001
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.009	0.991	0.001
M86.24 Subacute osteomyelitis (Hand)	0.009	0.991	0.001
M86.23 Subacute osteomyelitis (Forearm)	0.009	0.991	0.001
M86.22 Subacute osteomyelitis (Upper arm)	0.009	0.991	0.001
M86.21 Subacute osteomyelitis (Shoulder region)	0.009	0.991	0.001
M86.20 Subacute osteomyelitis (Multiple sites)	0.009	0.991	0.001
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.009	0.991	0.001
M86.38 Chronic multifocal osteomyelitis (Other)	0.009	0.991	0.001
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.009	0.991	0.001
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.009	0.991	0.001
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.009	0.991	0.001
M86.34 Chronic multifocal osteomyelitis (Hand)	0.009	0.991	0.001
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.009	0.991	0.001
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.009	0.991	0.001
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.009	0.991	0.001
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.009	0.991	0.001
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)	0.009	0.991	0.001
M86.58 Other chronic haematogenous osteomyelitis (Other)	0.009	0.991	0.001
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)	0.009	0.991	0.001
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)	0.009	0.991	0.001
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)	0.009	0.991	0.001
M86.54 Other chronic haematogenous osteomyelitis (Hand)	0.009	0.991	0.001
M86.53 Other chronic haematogenous osteomyelitis (Forearm)	0.009	0.991	0.001
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)	0.009	0.991	0.001
M86.51 Other chronic haematogenous osteomyelitis (Shoulder region)	0.009	0.991	0.001
M86.50 Other chronic haematogenous osteomyelitis (Multiple sites)	0.009	0.991	0.001
M86.86 Other osteomyelitis (Lower leg)	0.009	0.991	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.009	0.991	0.000
M86.19 Other acute osteomyelitis (Site unspecified)	0.008	0.991	0.001
M86.18 Other acute osteomyelitis (Other)	0.008	0.991	0.001
M86.16 Other acute osteomyelitis (Lower leg)	0.008	0.991	0.001
M86.15 Other acute osteomyelitis (Pelvic region and thigh)	0.008	0.991	0.001
M86.14 Other acute osteomyelitis (Hand)	0.008	0.991	0.001
M86.13 Other acute osteomyelitis (Forearm)	0.008	0.991	0.001
M86.12 Other acute osteomyelitis (Upper arm)	0.008	0.991	0.001
M86.11 Other acute osteomyelitis (Shoulder region)	0.008	0.991	0.001
M86.10 Other acute osteomyelitis (Multiple sites)	0.008	0.991	0.001
T36 Poisoning by systemic antibiotics	0.009	0.991	0.000
M86.89 Other osteomyelitis (Site unspecified)	0.008	0.991	0.001
M86.88 Other osteomyelitis (Other)	0.008	0.991	0.001
M86.84 Other osteomyelitis (Hand)	0.008	0.991	0.001
M86.83 Other osteomyelitis (Forearm)	0.008	0.991	0.001
M86.82 Other osteomyelitis (Upper arm)	0.008	0.991	0.001
M86.81 Other osteomyelitis (Shoulder region)	0.008	0.991	0.001
M86.80 Other osteomyelitis (Multiple sites)	0.008	0.991	0.001
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.008	0.991	0.000
M86.17 Other acute osteomyelitis (Ankle and foot)	0.008	0.991	0.001
T41 Poisoning by anaesthetics and therapeutic gases	0.008	0.991	0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.008	0.992	0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)	0.008	0.992	0.001
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.008	0.992	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.008	0.992	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.008	0.992	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.008	0.992	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.008	0.992	0.000
T38.1 Thyroid hormones and substitutes	0.008	0.992	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.008	0.992	0.000
M86.87 Other osteomyelitis (Ankle and foot)	0.007	0.992	0.001
T46 Poisoning by agents primarily affecting the cardiovascular system	0.008	0.992	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.008	0.992	0.000
M86.6 Other chronic osteomyelitis	0.007	0.992	0.001
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.008	0.992	0.000
C25 Malignant neoplasm of pancreas	0.000	0.993	0.007
T36.0 Penicillins	0.007	0.993	0.000
C25.0 Head of pancreas	0.000	0.993	0.007
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.007	0.993	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.007	0.993	0.000
T38.0 Glucocorticoids and synthetic analogues	0.007	0.993	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
M86.9 Osteomyelitis, unspecified	0.006	0.993	0.001
T43.9 Psychotropic drug, unspecified	0.007	0.993	0.000
T38.9 Other and unspecified hormone antagonists	0.007	0.993	0.000
T38.7 Androgens and anabolic congeners	0.007	0.993	0.000
T38.4 Oral contraceptives	0.007	0.993	0.000
T38.2 Antithyroid drugs	0.007	0.993	0.000
T43.6 Psychostimulants with abuse potential	0.007	0.993	0.000
S81.9 Open wound of lower leg, part unspecified	0.007	0.993	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.007	0.993	0.000
T38.5 Other oestrogens and progestogens	0.007	0.993	0.000
T43.2 Other and unspecified antidepressants	0.007	0.993	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
T36.4 Tetracyclines	0.006	0.993	0.000
C25.2 Tail of pancreas	0.000	0.993	0.006
T36.9 Systemic antibiotic, unspecified	0.006	0.993	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.993	0.000
T36.6 Rifamycins	0.006	0.993	0.000
T36.5 Aminoglycosides	0.006	0.993	0.000
T36.2 Chloramphenicol group	0.006	0.993	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.006	0.993	0.000
T41.5 Therapeutic gases	0.006	0.994	0.000
T41.4 Anaesthetic, unspecified	0.006	0.994	0.000
T41.3 Local anaesthetics	0.006	0.994	0.000
T41.2 Other and unspecified general anaesthetics	0.006	0.994	0.000
T41.1 Intravenous anaesthetics	0.006	0.994	0.000
T41.0 Inhaled anaesthetics	0.006	0.994	0.000
N21.0 Calculus in bladder	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
T48.4 Expectorants	0.006	0.994	0.000
T48.3 Antitussives	0.006	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
T48.0 Oxytocic drugs	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.006	0.994	0.000
T36.8 Other systemic antibiotics	0.006	0.994	0.000
C25.4 Endocrine pancreas	0.000	0.994	0.006
T48.5 Anti-common-cold drugs	0.006	0.994	0.000
T50.4 Drugs affecting uric acid metabolism	0.006	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
T47.7 Emetics	0.006	0.994	0.000
T47.5 Digestants	0.006	0.994	0.000
T47.3 Saline and osmotic laxatives	0.006	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T47.2 Stimulant laxatives	0.006	0.994	0.000
T49.9 Topical agent, unspecified	0.006	0.994	0.000
T49.8 Other topical agents	0.006	0.994	0.000
T49.7 Dental drugs, topically applied	0.006	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.994	0.000
T49.2 Local astringents and local detergents	0.006	0.994	0.000
T49.1 Antipruritics	0.006	0.994	0.000
S72.30 Fracture of shaft of femur (closed)	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
T46.7 Peripheral vasodilators	0.006	0.994	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.994	0.000
T37.5 Antiviral drugs	0.006	0.994	0.000
T37.4 Anthelminthics	0.006	0.994	0.000
T37.3 Other antiprotozoal drugs	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations