TreeWAS – Variant ID: rs2723279

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M50.1 Cervical disk disorder with radiculopathy	0.000	0.706	0.294
M50 Cervical disk disorders	0.000	0.717	0.283
M50.3 Other cervical disk degeneration	0.000	0.728	0.272
M50.0 Cervical disk disorder with myelopathy	0.000	0.753	0.247
M50.2 Other cervical disk displacement	0.000	0.772	0.228
M50.9 Cervical disk disorder, unspecified	0.000	0.798	0.202
M50.8 Other cervical disk disorders	0.000	0.811	0.189
M50-M54 Other dorsopathies	0.000	0.881	0.119
M51.2 Other specified intervertebral disk displacement	0.000	0.892	0.108
M51 Other intervertebral disk disorders	0.000	0.892	0.108
M53 Other dorsopathies, not elsewhere classified	0.000	0.907	0.093
M51.4 Schmorl's nodes	0.000	0.913	0.087
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.923	0.077
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.925	0.075
M53.8 Other specified dorsopathies	0.000	0.927	0.073
M51.3 Other specified intervertebral disk degeneration	0.000	0.930	0.069
M53.9 Dorsopathy, unspecified	0.000	0.930	0.069
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.000	0.930	0.070
M53.1 Cervicobrachial syndrome	0.000	0.933	0.067
M53.0 Cervicocranial syndrome	0.000	0.933	0.067
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.065	0.935	0.000
M53.2 Spinal instabilities	0.000	0.939	0.061
M53.82 Other specified dorsopathies (Cervical region)	0.000	0.941	0.059
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns	0.000	0.943	0.057
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.944	0.055
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.944	0.055
O42 Premature rupture of membranes	0.054	0.946	0.000
M53.96 Dorsopathy, unspecified (Lumbar region)	0.000	0.947	0.053
M51.8 Other specified intervertebral disk disorders	0.000	0.947	0.053
M53.89 Other specified dorsopathies (Site unspecified)	0.000	0.947	0.052
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)	0.000	0.947	0.052
M53.87 Other specified dorsopathies (Lumbosacral region)	0.000	0.947	0.052
M53.85 Other specified dorsopathies (Thoracolumbar region)	0.000	0.947	0.052
M53.84 Other specified dorsopathies (Thoracic region)	0.000	0.947	0.052
M53.83 Other specified dorsopathies (Cervicothoracic region)	0.000	0.947	0.052
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)	0.000	0.947	0.052
M53.80 Other specified dorsopathies (Multiple sites in spine)	0.000	0.947	0.052
D68 Other coagulation defects	0.000	0.948	0.052
M53.86 Other specified dorsopathies (Lumbar region)	0.000	0.948	0.051
D68.9 Coagulation defect, unspecified	0.000	0.948	0.052
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.050	0.950	0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac	0.000	0.950	0.050
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar	0.000	0.950	0.050
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol	0.000	0.950	0.050
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic	0.000	0.950	0.050
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot	0.000	0.950	0.050
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical	0.000	0.950	0.050
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-	0.000	0.950	0.050
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit	0.000	0.950	0.050
M53.99 Dorsopathy, unspecified (Site unspecified)	0.000	0.950	0.050
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)	0.000	0.950	0.050
M53.97 Dorsopathy, unspecified (Lumbosacral region)	0.000	0.950	0.050
M53.95 Dorsopathy, unspecified (Thoracolumbar region)	0.000	0.950	0.050
M53.94 Dorsopathy, unspecified (Thoracic region)	0.000	0.950	0.050
M53.93 Dorsopathy, unspecified (Cervicothoracic region)	0.000	0.950	0.050
M53.92 Dorsopathy, unspecified (Cervical region)	0.000	0.950	0.050
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)	0.000	0.950	0.050
M53.90 Dorsopathy, unspecified (Multiple sites in spine)	0.000	0.950	0.050
B07 Viral warts	0.000	0.950	0.050
D68.8 Other specified coagulation defects	0.000	0.950	0.050
D68.2 Hereditary deficiency of other clotting factors	0.000	0.952	0.048
M53.09 Cervicocranial syndrome-Site unspe	0.000	0.952	0.048
M53.08 Cervicocranial syndrome-Sacral/sacrococ	0.000	0.952	0.048
M53.07 Cervicocranial syndrome-Lumbosacral	0.000	0.952	0.048
M53.06 Cervicocranial syndrome-Lumbar	0.000	0.952	0.048
M53.05 Cervicocranial syndrome-Thoracolumbar	0.000	0.952	0.048
M53.04 Cervicocranial syndrome-Thoracic	0.000	0.952	0.048
M53.03 Cervicocranial syndrome (Cervicothoracic region)	0.000	0.952	0.048
M53.02 Cervicocranial syndrome (Cervical region)	0.000	0.952	0.048
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)	0.000	0.952	0.048
M53.00 Cervicocranial syndrome (Multiple sites in spine)	0.000	0.952	0.048
M53.19 Cervicobrachial syndrome-Site unspe	0.000	0.952	0.048
M53.18 Cervicobrachial syndrome-Sacral/sacrococ	0.000	0.952	0.048
M53.17 Cervicobrachial syndrome-Lumbosacral	0.000	0.952	0.048
M53.16 Cervicobrachial syndrome-Lumbar	0.000	0.952	0.048
M53.15 Cervicobrachial syndrome-Thoracolumbar	0.000	0.952	0.048
M53.14 Cervicobrachial syndrome-Thoracic	0.000	0.952	0.048
M53.13 Cervicobrachial syndrome (Cervicothoracic region)	0.000	0.952	0.048
M53.12 Cervicobrachial syndrome (Cervical region)	0.000	0.952	0.048
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)	0.000	0.952	0.048
M53.10 Cervicobrachial syndrome (Multiple sites in spine)	0.000	0.952	0.048
D68.6 Other Thrombophilia	0.000	0.953	0.047
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.000	0.956	0.044
M53.29 Spinal instabilities (Site unspecified)	0.000	0.956	0.044
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)	0.000	0.956	0.044
M53.25 Spinal instabilities (Thoracolumbar region)	0.000	0.956	0.044
M53.24 Spinal instabilities (Thoracic region)	0.000	0.956	0.044
M53.23 Spinal instabilities (Cervicothoracic region)	0.000	0.956	0.044
M53.22 Spinal instabilities (Cervical region)	0.000	0.956	0.044
M53.21 Spinal instabilities (Occipito-atlanto-axial region)	0.000	0.956	0.044
M53.20 Spinal instabilities (Multiple sites in spine)	0.000	0.956	0.044
O42.9 Premature rupture of membranes, unspecified	0.044	0.956	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.957	0.043
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.958	0.042
M53.26 Spinal instabilities (Lumbar region)	0.000	0.958	0.042
O42.2 Premature rupture of membranes, labour delayed by therapy	0.042	0.958	0.000
M53.27 Spinal instabilities (Lumbosacral region)	0.000	0.959	0.041
D68.5 Primary Thrombophilia	0.000	0.960	0.040
D68.1 Hereditary factor XI deficiency	0.000	0.963	0.037
M51.9 Intervertebral disk disorder, unspecified	0.001	0.967	0.032
D68.0 Von Willebrand's disease	0.000	0.971	0.029
D68.4 Acquired coagulation factor deficiency	0.000	0.972	0.028
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.000	0.981	0.019
B00 Herpesviral [herpes simplex] infections	0.000	0.982	0.018
B00.9 Herpesviral infection, unspecified	0.000	0.984	0.016
B00.5 Herpesviral ocular disease	0.000	0.984	0.015
D22.7 Melanocytic naevi of lower limb, including hip	0.000	0.986	0.014
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.000	0.986	0.014
B06 Rubella [German measles]	0.000	0.986	0.014
B05 Measles	0.000	0.986	0.014
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.000	0.986	0.014
B04 Monkeypox	0.000	0.986	0.014
B03 Smallpox	0.000	0.986	0.014
B00.8 Other forms of herpesviral infection	0.000	0.987	0.013
B00.7 Disseminated herpesviral disease	0.000	0.987	0.013
B00.3 Herpesviral meningitis	0.000	0.987	0.013
B00.0 Eczema herpeticum	0.000	0.987	0.013
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.987	0.013
B00.1 Herpesviral vesicular dermatitis	0.000	0.987	0.013
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.988	0.012
B01 Varicella [chickenpox]	0.000	0.988	0.011
D18.0 Haemangioma, any site	0.000	0.989	0.011
B05.9 Measles without complication	0.000	0.990	0.010
B05.8 Measles with other complications	0.000	0.990	0.010
B05.4 Measles with intestinal complications	0.000	0.990	0.010
B05.3 Measles complicated by otitis media	0.000	0.990	0.010
B05.2 Measles complicated by pneumonia	0.000	0.990	0.010
B05.1 Measles complicated by meningitis	0.000	0.990	0.010
B05.0 Measles complicated by encephalitis	0.000	0.990	0.010
B06.9 Rubella without complication	0.000	0.990	0.010
B06.8 Rubella with other complications	0.000	0.990	0.010
B06.0 Rubella with neurological complications	0.000	0.990	0.010
B02 Zoster [herpes zoster]	0.000	0.990	0.010
R44.3 Hallucinations, unspecified	0.000	0.990	0.010
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.990	0.010
D67 Hereditary factor IX deficiency	0.000	0.990	0.009
B00.4 Herpesviral encephalitis	0.000	0.991	0.009
D66 Hereditary factor VIII deficiency	0.000	0.991	0.009
C25.9 Pancreas, unspecified	0.000	0.991	0.009
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.000	0.991	0.009
B08.5 Enteroviral vesicular pharyngitis	0.000	0.991	0.009
B08.4 Enteroviral vesicular stomatitis with exanthem	0.000	0.991	0.009
B08.3 Erythema infectiosum [fifth disease]	0.000	0.991	0.009
B08.2 Exanthema subitum [sixth disease]	0.000	0.991	0.009
B08.0 Other orthopoxvirus infections	0.000	0.991	0.009
B01.8 Varicella with other complications	0.000	0.991	0.008
B01.2 Varicella pneumonia	0.000	0.991	0.008
B01.1 Varicella encephalitis	0.000	0.991	0.008
B01.0 Varicella meningitis	0.000	0.991	0.008
K50.1 Crohn's disease of large intestine	0.009	0.991	0.000
B02.7 Disseminated zoster	0.000	0.992	0.008
B02.1 Zoster meningitis	0.000	0.992	0.008
B02.0 Zoster encephalitis	0.000	0.992	0.008
B02.2 Zoster with other nervous system involvement	0.000	0.992	0.008
B08.1 Molluscum contagiosum	0.000	0.993	0.007
B02.8 Zoster with other complications	0.000	0.993	0.007
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.007	0.993	0.000
N30.3 Trigonitis	0.000	0.993	0.007
B02.9 Zoster without complication	0.000	0.993	0.007
J11.1 Influenza with other respiratory manifestations, virus not identified	0.000	0.993	0.007
B01.9 Varicella without complications	0.000	0.994	0.006
B02.3 Zoster ocular disease	0.000	0.994	0.006
R50.9 Fever, unspecified	0.000	0.994	0.006
R50.0 Fever with chills	0.000	0.994	0.006
S22.40 Multiple fractures of ribs (closed)	0.000	0.994	0.006
R50 Fever of unknown origin	0.000	0.994	0.006
D18 Haemangioma and lymphangioma, any site	0.000	0.994	0.006
S22.4 Multiple fractures of ribs	0.000	0.995	0.005
C83.3 Large cell (diffuse)	0.000	0.995	0.005
R50.8 Other specified fever	0.000	0.995	0.005
R41.3 Other amnesia	0.000	0.995	0.005
D22.0 Melanocytic naevi of lip	0.000	0.995	0.005
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.995	0.005
D18.1 Lymphangioma, any site	0.000	0.995	0.005
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.995	0.005
D69 Purpura and other haemorrhagic conditions	0.000	0.995	0.005
K75.8 Other specified inflammatory liver diseases	0.005	0.995	0.000
R50.2 Drug-induced fever	0.000	0.995	0.005
C83.0 Small cell (diffuse)	0.000	0.995	0.005
R61.9 Hyperhidrosis, unspecified	0.005	0.995	0.000
I12.9 Hypertensive renal disease without renal failure	0.005	0.995	0.000
S22.2 Fracture of sternum	0.000	0.995	0.004
C25 Malignant neoplasm of pancreas	0.000	0.996	0.004
R50.1 Persistent fever	0.000	0.996	0.004
Y51 Drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.996	0.004
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.996	0.004
D22 Melanocytic naevi	0.000	0.996	0.004
S22.20 Fracture of sternum (closed)	0.000	0.996	0.004
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.996	0.004
S22.41 Multiple fractures of ribs (open)	0.000	0.996	0.004
D69.2 Other nonthrombocytopenic purpura	0.000	0.996	0.004
S20-S29 Injuries to the thorax	0.000	0.996	0.004
R44.1 Visual hallucinations	0.000	0.996	0.004
S22.0 Fracture of thoracic vertebra	0.000	0.996	0.004
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.996	0.004
S20 Superficial injury of thorax	0.000	0.996	0.004
C25.1 Body of pancreas	0.000	0.996	0.004
S22.5 Flail chest	0.000	0.996	0.004
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.996	0.004
C25.2 Tail of pancreas	0.000	0.996	0.004
D22.4 Melanocytic naevi of scalp and neck	0.000	0.996	0.004
S22.1 Multiple fractures of thoracic spine	0.000	0.996	0.004
E16.2 Hypoglycaemia, unspecified	0.004	0.996	0.000
S22.9 Fracture of bony thorax, part unspecified	0.000	0.996	0.004
S22.8 Fracture of other parts of bony thorax	0.000	0.996	0.004
C25.3 Pancreatic duct	0.000	0.996	0.004
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.996	0.004
D69.8 Other specified haemorrhagic conditions	0.000	0.996	0.004
M84.04 Malunion of fracture (Hand)	0.004	0.996	0.000
W29.9 Unspecified place	0.004	0.996	0.000
S21 Open wound of thorax	0.000	0.996	0.004
M84.06 Malunion of fracture (Lower leg)	0.004	0.996	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.996	0.004
D22.2 Melanocytic naevi of ear and external auricular canal	0.000	0.996	0.004
D69.1 Qualitative platelet defects	0.000	0.996	0.003
S27.2 Traumatic heamopneumothorax	0.000	0.996	0.003
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.003	0.996	0.000
Y57.8 Other drugs and medicaments	0.004	0.996	0.000
D69.0 Allergic purpura	0.000	0.996	0.003
S27 Injury of other and unspecified intrathoracic organs	0.000	0.996	0.003
S22.21 Fracture of sternum (open)	0.000	0.996	0.003
D69.9 Haemorrhagic condition, unspecified	0.000	0.996	0.003
M84.0 Malunion of fracture	0.003	0.996	0.000
C25.8 Overlapping lesion of pancreas	0.000	0.997	0.003
E16.1 Other hypoglycaemia	0.003	0.997	0.000
J11 Influenza, virus not identified	0.000	0.997	0.003
D33.3 Cranial nerves	0.000	0.997	0.003
D22.3 Melanocytic naevi of other and unspecified parts of face	0.000	0.997	0.003
I15.9 Seconday hypertension, unspecified	0.003	0.997	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.997	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.997	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.997	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.003	0.997	0.000
Y51.0 Anticholinesterase agents	0.003	0.997	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.000	0.997	0.003
D69.5 Secondary thrombocytopenia	0.000	0.997	0.003
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.997	0.003
D69.6 Thrombocytopenia, unspecified	0.000	0.997	0.003
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.997	0.003
C25.7 Other parts of pancreas	0.000	0.997	0.003
R44.2 Other hallucinations	0.000	0.997	0.003
S22.3 Fracture of rib	0.000	0.997	0.003
R44.0 Auditory hallucinations	0.000	0.997	0.003
S20.3 Other superficial injuries of front wall of thorax	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
S24 Injury of nerves and spinal cord at thorax level	0.000	0.997	0.003
S21.2 Open wound of back wall of thorax	0.000	0.997	0.003
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.003
C83.5 Lymphoblastic (diffuse)	0.000	0.997	0.003
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.003
C83.2 Mixed small and large cell (diffuse)	0.000	0.997	0.003
S12.2 Fracture of other specified cervical vertebra	0.000	0.997	0.003
M84.03 Malunion of fracture (Forearm)	0.003	0.997	0.000
S20.2 Contusion of thorax	0.000	0.997	0.003
E16 Other disorders of pancreatic internal secretion	0.003	0.997	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.000	0.997	0.003
S26 Injury of heart	0.000	0.997	0.003
S25 Injury of blood vessels of thorax	0.000	0.997	0.003
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.000	0.997	0.003
S22.01 Fracture of thoracic vertebra (open)	0.000	0.997	0.003
C83.7 Burkitt's tumour	0.000	0.997	0.003
S21.1 Open wound of front wall of thorax	0.000	0.997	0.003
S22.50 Flail chest (closed)	0.000	0.997	0.003
D69.4 Other primary thrombocytopenia	0.000	0.997	0.003
R41.2 Retrograde amnesia	0.000	0.997	0.003
S20.7 Multiple superficial injuries of thorax	0.000	0.997	0.003
S27.1 Traumatic haemothorax	0.000	0.997	0.003
I15 Secondary hypertension	0.003	0.997	0.000
C02.9 Tongue, unspecified	0.000	0.997	0.003
M84.07 Malunion of fracture (Ankle and foot)	0.003	0.997	0.000
I15.1 Hypertension secondary to other renal disorders	0.003	0.997	0.000
S22.51 Flail chest (open)	0.000	0.997	0.003
S20.1 Other and unspecified superficial injuries of breast	0.000	0.997	0.003
M84.02 Malunion of fracture (Upper arm)	0.003	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.000	0.997	0.003
C25.4 Endocrine pancreas	0.000	0.997	0.003
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.997	0.003
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.997	0.003
S22.81 Fracture of other parts of bony thorax (open)	0.000	0.997	0.003
S22.80 Fracture of other parts of bony thorax (closed)	0.000	0.997	0.003
S22.91 Fracture of bony thorax, part unspecified (open)	0.000	0.997	0.003
S22.90 Fracture of bony thorax, part unspecified (closed)	0.000	0.997	0.003
S29 Other and unspecified injuries of thorax	0.000	0.997	0.003
Y52.3 Coronary vasodilators, not elsewhere classified	0.003	0.997	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.997	0.003
I15.2 Hypertension secondary to endocrine disorders	0.003	0.997	0.000
S21.8 Open wound of other parts of thorax	0.000	0.997	0.003
S21.7 Multiple open wounds of thoracic wall	0.000	0.997	0.003
S21.0 Open wound of breast	0.000	0.997	0.003
M84.05 Malunion of fracture (Pelvic region and thigh)	0.003	0.997	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
C25.0 Head of pancreas	0.000	0.997	0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.997	0.003
J11.0 Influenza with pneumonia, virus not identified	0.000	0.997	0.003
S99.9 Unspecified injury of ankle and foot	0.000	0.997	0.003
Y57 Other and unspecified drugs and medicaments	0.003	0.997	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.997	0.003
S27.7 Multiple injuries of intrathoracic organs	0.000	0.997	0.003
S27.6 Injury of pleura	0.000	0.997	0.003
S27.5 Injury of thoracic trachea	0.000	0.997	0.003
S27.4 Injury of bronchus	0.000	0.997	0.003
M84.09 Malunion of fracture (Site unspecified)	0.003	0.997	0.000
M84.08 Malunion of fracture (Other)	0.003	0.997	0.000
M84.00 Malunion of fracture (Multiple sites)	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
I12 Hypertensive renal disease	0.003	0.997	0.000
J11.8 Influenza with other manifestations, virus not identified	0.000	0.997	0.003
S20.4 Other superficial injuries of back wall of thorax	0.000	0.997	0.003
S20.0 Contusion of breast	0.000	0.997	0.003
S21.9 Open wound of thorax, part unspecified	0.000	0.997	0.003
R41.0 Disorientation, unspecified	0.000	0.997	0.003
S24.1 Other and unspecified injuries of thoracic spinal cord	0.000	0.997	0.003
S22.31 Fracture of rib (open)	0.000	0.997	0.003
S24.6 Injury of unspecified nerve of thorax	0.000	0.997	0.002
S24.5 Injury of other nerves of thorax	0.000	0.997	0.002
S24.4 Injury of thoracic sympathetic nerves	0.000	0.997	0.002
S24.3 Injury of peripheral nerves of thorax	0.000	0.997	0.002
S24.2 Injury of nerve root of thoracic spine	0.000	0.997	0.002
S24.0 Concussion and oedema of thoracic spinal cord	0.000	0.997	0.002
R41.1 Anterograde amnesia	0.000	0.997	0.003
Y49.2 Other and unspecified antidepressants	0.003	0.997	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.997	0.002
S27.8 Injury of other specified intrathoracic organs	0.000	0.997	0.002
N30.8 Other cystitis	0.000	0.997	0.003
S27.3 Other injuries of lung	0.000	0.997	0.002
E16.9 Disorder of pancreatic internal secretion, unspecified	0.002	0.997	0.000
E16.8 Other specified disorders of pancreatic internal secretion	0.002	0.997	0.000
E16.4 Abnormal secretion of gastrin	0.002	0.997	0.000
E16.3 Increased secretion of glucagon	0.002	0.997	0.000
G96.0 Cerebrospinal fluid leak	0.000	0.997	0.003
S23.5 Sprain and strain of other and unspecified parts of thorax	0.000	0.997	0.002
S23.4 Sprain and strain of ribs and sternum	0.000	0.997	0.002
S23.3 Sprain and strain of thoracic spine	0.000	0.997	0.002
S23.2 Dislocation of other and unspecified parts of thorax	0.000	0.997	0.002
S23.1 Dislocation of thoracic vertebra	0.000	0.997	0.002
S23.0 Traumatic rupture of thoracic intervertebral disk	0.000	0.997	0.002
S25.9 Injury of unspecified blood vessel of thorax	0.000	0.997	0.002
S25.8 Injury of other blood vessels of thorax	0.000	0.997	0.002
S25.7 Injury of multiple blood vessels of thorax	0.000	0.997	0.002
S25.5 Injury of intercostal blood vessels	0.000	0.997	0.002
S25.4 Injury of pulmonary blood vessels	0.000	0.997	0.002
S25.3 Injury of innominate or subclavian vein	0.000	0.997	0.002
S25.2 Injury of superior vena cava	0.000	0.997	0.002
S25.1 Injury of innominate or subclavian artery	0.000	0.997	0.002
S25.0 Injury of thoracic aorta	0.000	0.997	0.002
S26.9 Injury of heart, unspecified	0.000	0.997	0.002
S26.8 Other injuries of heart	0.000	0.997	0.002
S26.0 Injury of heart with haemopericardium	0.000	0.997	0.002
S28.1 Traumatic amputation of part of thorax	0.000	0.997	0.002
S28.0 Crushed chest	0.000	0.997	0.002
Y52 Agents primarily affecting the cardiovascular system	0.003	0.997	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.997	0.003
I15.8 Other secondary hypertension	0.002	0.997	0.000
I15.0 Renovascular hypertension	0.002	0.997	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.997	0.002
L60.0 Ingrowing nail	0.000	0.997	0.003
T92.1 Sequelae of fracture of arm	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.002	0.997	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.002
R46 Symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.002
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.000	0.998	0.002
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.000	0.998	0.002
S29.0 Injury of muscle and tendon at thorax level	0.000	0.998	0.002
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
N30 Cystitis	0.000	0.998	0.002
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
R46.8 Other symptoms and signs involving appearance and behaviour	0.000	0.998	0.002
S12 Fracture of neck	0.000	0.998	0.002
M70.65 Trochanteric bursitis-Pelvic/Thigh	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.000	0.998	0.002
S29.9 Unspecified injury of thorax	0.000	0.998	0.002
Y54.5 Other diuretics	0.002	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
Y57.7 Vitamins, not elsewhere classified	0.002	0.998	0.000
Y57.4 Pharmaceutical excipients	0.002	0.998	0.000
Y57.3 Alcohol deterrents	0.002	0.998	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
Y57.1 Lipotropic drugs	0.002	0.998	0.000
Y57.0 Appetite depressants [anorectics]	0.002	0.998	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.002
N30.4 Irradiation cystitis	0.000	0.998	0.002
N30.0 Acute cystitis	0.000	0.998	0.002
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.002	0.998	0.000
C77.9 Lymph node, unspecified	0.000	0.998	0.002
D22.5 Melanocytic naevi of trunk	0.000	0.998	0.002
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.000	0.998	0.002
Y57.6 Other diagnostic agents	0.002	0.998	0.000
Y57.5 X-ray contrast media	0.002	0.998	0.000
R46.2 Strange and inexplicable behaviour	0.000	0.998	0.002
R46.0 Very low level of personal hygiene	0.000	0.998	0.002
K35.3 Acute appendicitis with localized peritonitis	0.000	0.998	0.002
Z52.4 Kidney donor	0.000	0.998	0.002
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
G93.9 Disorder of brain, unspecified	0.000	0.998	0.002
S27.0 Traumatic pneumothorax	0.000	0.998	0.002
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
T92 Sequelae of injuries of upper limb	0.002	0.998	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.000	0.998	0.002
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.000	0.998	0.002
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.000	0.998	0.002
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.000	0.998	0.002
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.000	0.998	0.002
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.000	0.998	0.002
K91.3 Postoperative intestinal obstruction	0.000	0.998	0.002
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.002	0.998	0.000
Y52.7 Peripheral vasodilators	0.002	0.998	0.000
W29 Contact with other powered hand tools and household machinery	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.000	0.998	0.002
D22.9 Melanocytic naevi, unspecified	0.000	0.998	0.002
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.998	0.002
R46.7 Verbosity and circumstantial detail obscuring reason for contact	0.000	0.998	0.002
R46.6 Undue concern and preoccupation with stressful events	0.000	0.998	0.002
R46.5 Suspiciousness and marked evasiveness	0.000	0.998	0.002
R46.3 Overactivity	0.000	0.998	0.002
R46.1 Bizarre personal appearance	0.000	0.998	0.002
S12.71 Multiple fractures of cervical spine (open)	0.000	0.998	0.002
G96 Other disorders of central nervous system	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
S12.8 Fracture of other parts of neck	0.000	0.998	0.002
S12.0 Fracture of first cervical vertebra	0.000	0.998	0.002
Y53 Agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
S01.1 Open wound of eyelid and periocular area	0.002	0.998	0.000
Y49.5 Other antipsychotics and neuroleptics	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
M47.99 Spondylosis, unspecified (Site unspecified)	0.002	0.998	0.000
H35.4 Peripheral retinal degeneration	0.000	0.998	0.002
S01.9 Open wound of head, part unspecified	0.002	0.998	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.002	0.998	0.000
Y54.7 Agents affecting calcification	0.002	0.998	0.000
K35 Acute appendicitis	0.000	0.998	0.002
R61 Hyperhidrosis	0.002	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.002	0.998	0.000
R46.4 Slowness and poor responsiveness	0.000	0.998	0.002
Y49.9 Psychotropic drug, unspecified	0.002	0.998	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
Y49.7 Psychostimulants with abuse potential	0.002	0.998	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.002	0.998	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.998	0.002
B37.0 Candidal stomatitis	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.002
T92.9 Sequelae of unspecified injury of upper limb	0.002	0.998	0.000
R43 Disturbances of smell and taste	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.002	0.998	0.000
Y53.4 Other laxatives	0.002	0.998	0.000
Y59.0 Viral vaccines	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.998	0.002
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.998	0.002
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.002
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
K25.0 Acute with haemorrhage	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
G95.1 Vascular myelopathies	0.000	0.998	0.002
G96.8 Other specified disorders of central nervous system	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.000	0.998	0.002
Y41.0 Sulphonamides	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations