TreeWAS – Variant ID: rs2734331

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J45.9 Asthma, unspecified	0.000	0.001	0.999
J45 Asthma	0.000	0.174	0.826
J40-J47 Chronic lower respiratory diseases	0.000	0.266	0.734
J44 Other chronic obstructive pulmonary disease	0.000	0.315	0.685
J47 Bronchiectasis	0.000	0.344	0.656
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.364	0.636
J45.8 Mixed asthma	0.000	0.408	0.592
J45.1 Nonallergic asthma	0.000	0.408	0.592
J40 Bronchitis, not specified as acute or chronic	0.000	0.408	0.592
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.442	0.558
J46 Status asthmaticus	0.000	0.458	0.541
J41 Simple and mucopurulent chronic bronchitis	0.001	0.474	0.526
J45.0 Predominantly allergic asthma	0.000	0.488	0.511
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.494	0.506
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.548	0.452
J43 Emphysema	0.000	0.555	0.445
J42 Unspecified chronic bronchitis	0.001	0.614	0.385
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.622	0.377
J41.1 Mucopurulent chronic bronchitis	0.000	0.622	0.377
J41.0 Simple chronic bronchitis	0.000	0.622	0.377
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.332	0.668	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.331	0.669	0.000
J43.8 Other emphysema	0.000	0.681	0.319
J43.2 Centrilobular emphysema	0.000	0.681	0.319
J43.1 Panlobular emphysema	0.000	0.681	0.319
J43.0 MacLeod's syndrome	0.000	0.681	0.319
T88 Other complications of surgical and medical care, not elsewhere classified	0.312	0.688	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.311	0.689	0.000
S20-S29 Injuries to the thorax	0.308	0.692	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.305	0.695	0.000
S32 Fracture of lumbar spine and pelvis	0.297	0.703	0.000
T66-T78 Other and unspecified effects of external causes	0.289	0.711	0.000
S90-S99 Injuries to the ankle and foot	0.285	0.715	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.282	0.718	0.000
T92 Sequelae of injuries of upper limb	0.280	0.720	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.277	0.723	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.277	0.723	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.277	0.723	0.000
S10-S19 Injuries to the neck	0.276	0.724	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.273	0.727	0.000
T86 Failure and rejection of transplanted organs and tissues	0.272	0.728	0.000
S70-S79 Injuries to the hip and thigh	0.271	0.729	0.000
S32.0 Fracture of lumbar vertebra	0.268	0.732	0.000
S27 Injury of other and unspecified intrathoracic organs	0.265	0.735	0.000
T88.4 Failed or difficult intubation	0.262	0.738	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.262	0.738	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.260	0.740	0.000
T00-T07 Injuries involving multiple body regions	0.259	0.741	0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.259	0.741	0.000
T79-T79 Certain early complications of trauma	0.258	0.742	0.000
S22.4 Multiple fractures of ribs	0.256	0.744	0.000
T78 Adverse effects, not elsewhere classified	0.254	0.746	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.253	0.747	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.248	0.752	0.000
Chapter X Diseases of the respiratory system	0.038	0.753	0.209
T93 Sequelae of injuries of lower limb	0.246	0.754	0.000
S32.5 Fracture of pubis	0.245	0.755	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.241	0.759	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.239	0.761	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.238	0.761	0.000
T33-T35 Frostbite	0.238	0.762	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.238	0.762	0.000
S22.40 Multiple fractures of ribs (closed)	0.238	0.762	0.000
T87 Complications peculiar to reattachment and amputation	0.237	0.762	0.000
J43.9 Emphysema, unspecified	0.000	0.762	0.237
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.236	0.764	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.236	0.764	0.000
I30-I52 Other forms of heart disease	0.235	0.765	0.000
S27.0 Traumatic pneumothorax	0.234	0.766	0.000
T86.1 Kidney transplant failure and rejection	0.234	0.766	0.000
S92 Fracture of foot, except ankle	0.234	0.766	0.000
S32.3 Fracture of ilium	0.233	0.767	0.000
I44 Atrioventricular and left bundle-branch block	0.231	0.769	0.000
I44.0 Atrioventricular block, first degree	0.231	0.769	0.000
T78.4 Allergy, unspecified	0.230	0.770	0.000
S22.3 Fracture of rib	0.229	0.771	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.228	0.772	0.000
I46 Cardiac arrest	0.227	0.772	0.000
S60-S69 Injuries to the wrist and hand	0.227	0.773	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.225	0.774	0.000
S99 Other and unspecified injuries of ankle and foot	0.225	0.775	0.000
T14 Injury of unspecified body region	0.224	0.776	0.000
T92.1 Sequelae of fracture of arm	0.224	0.776	0.000
S12 Fracture of neck	0.224	0.776	0.000
T88.9 Complication of surgical and medical care, unspecified	0.224	0.776	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.224	0.776	0.000
T88.5 Other complications of anaesthesia	0.224	0.776	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.224	0.776	0.000
T88.2 Shock due to anaesthesia	0.224	0.776	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.224	0.776	0.000
T88.0 Infection following immunisation	0.224	0.776	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.224	0.776	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.223	0.777	0.000
S37 Injury of urinary and pelvic organs	0.223	0.777	0.000
S36 Injury of intra-abdominal organs	0.223	0.777	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.223	0.777	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.223	0.777	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.223	0.777	0.000
S31 Open wound of abdomen, lower back and pelvis	0.223	0.777	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.223	0.777	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.223	0.777	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.222	0.778	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.221	0.779	0.000
S26 Injury of heart	0.221	0.779	0.000
S25 Injury of blood vessels of thorax	0.221	0.779	0.000
S24 Injury of nerves and spinal cord at thorax level	0.221	0.779	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.221	0.779	0.000
S21 Open wound of thorax	0.221	0.779	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.221	0.779	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.220	0.780	0.000
T13 Other injuries of lower limb, level unspecified	0.219	0.781	0.000
T98 Sequelae of other and unspecified effects of external causes	0.219	0.781	0.000
T95 Sequelae of burns, corrosions and frostbite	0.219	0.781	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.219	0.781	0.000
T91 Sequelae of injuries of neck and trunk	0.219	0.781	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.219	0.781	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.219	0.781	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.219	0.781	0.000
I46.0 Cardiac arrest with successful resuscitation	0.219	0.781	0.000
T81 Complications of procedures, not elsewhere classified	0.217	0.783	0.000
S91 Open wound of ankle and foot	0.217	0.783	0.000
N20-N23 Urolithiasis	0.217	0.783	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.217	0.783	0.000
S71 Open wound of hip and thigh	0.216	0.783	0.000
S10 Superficial injury of neck	0.216	0.784	0.000
N17-N19 Renal failure	0.216	0.784	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.216	0.784	0.000
T68 Hypothermia	0.215	0.784	0.000
Chapter XIV Diseases of the genitourinary system	0.214	0.786	0.000
J90-J94 Other diseases of pleura	0.011	0.786	0.203
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.213	0.787	0.000
S32.2 Fracture of coccyx	0.213	0.787	0.000
S32.1 Fracture of sacrum	0.213	0.787	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.212	0.787	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.212	0.788	0.000
S29 Other and unspecified injuries of thorax	0.211	0.788	0.000
I44.1 Atrioventricular block, second degree	0.211	0.788	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.211	0.789	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.211	0.789	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.211	0.789	0.000
Chapter IX Diseases of the circulatory system	0.211	0.789	0.000
I71 Aortic aneurysm and dissection	0.210	0.790	0.000
S32.50 Fracture of pubis (closed)	0.209	0.791	0.000
T23 Burn and corrosion of wrist and hand	0.208	0.791	0.000
S22.1 Multiple fractures of thoracic spine	0.208	0.792	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.208	0.792	0.000
N19 Unspecified renal failure	0.208	0.792	0.000
T82.1 Mechanical complication of cardiac electronic device	0.208	0.792	0.000
T75 Effects of other external causes	0.207	0.793	0.000
T74 Maltreatment syndromes	0.207	0.793	0.000
T73 Effects of other deprivation	0.207	0.793	0.000
T70 Effects of air pressure and water pressure	0.207	0.793	0.000
T69 Other effects of reduced temperature	0.207	0.793	0.000
T67 Effects of heat and light	0.207	0.793	0.000
T71 Asphyxiation	0.207	0.793	0.000
T66 Unspecified effects of radiation	0.207	0.793	0.000
T02 Fractures involving multiple body regions	0.207	0.793	0.000
S70 Superficial injury of hip and thigh	0.206	0.793	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.206	0.794	0.000
T90 Sequelae of injuries of head	0.206	0.794	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.205	0.795	0.000
# Top node	0.205	0.795	0.000
N40 Hyperplasia of prostate	0.205	0.795	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.204	0.795	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.205	0.795	0.000
S98 Traumatic amputation of ankle and foot	0.204	0.795	0.000
S97 Crushing injury of ankle and foot	0.204	0.795	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.204	0.795	0.000
S95 Injury of blood vessels at ankle and foot level	0.204	0.795	0.000
S94 Injury of nerves at ankle and foot level	0.204	0.795	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.204	0.795	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.204	0.796	0.000
I47 Paroxysmal tachycardia	0.204	0.796	0.000
S20 Superficial injury of thorax	0.204	0.796	0.000
N20 Calculus of kidney and ureter	0.203	0.797	0.000
S22.2 Fracture of sternum	0.203	0.797	0.000
S50-S59 Injuries to the elbow and forearm	0.203	0.797	0.000
S22.9 Fracture of bony thorax, part unspecified	0.202	0.797	0.000
S22.8 Fracture of other parts of bony thorax	0.202	0.797	0.000
S22.5 Flail chest	0.202	0.797	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.202	0.798	0.000
N40-N51 Diseases of male genital organs	0.202	0.798	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.202	0.798	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.201	0.799	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.201	0.799	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.201	0.799	0.000
T92.0 Sequelae of open wound of upper limb	0.201	0.799	0.000
Chapter XX External causes of morbidity and mortality	0.201	0.799	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.200	0.800	0.000
J90 Pleural effusion, not elsewhere classified	0.000	0.800	0.200
S90 Superficial injury of ankle and foot	0.200	0.800	0.000
T11 Other injuries of upper limb, level unspecified	0.199	0.801	0.000
T09 Other injuries of spine and trunk, level unspecified	0.199	0.801	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.199	0.801	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.199	0.801	0.000
T12 Fracture of lower limb, level unspecified	0.199	0.801	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.199	0.801	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.199	0.801	0.000
T10 Fracture of upper limb, level unspecified	0.199	0.801	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.199	0.801	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.199	0.801	0.000
T08 Fracture of spine, level unspecified	0.199	0.801	0.000
S61 Open wound of wrist and hand	0.199	0.801	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.198	0.801	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.198	0.801	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.198	0.801	0.000
T83.2 Mechanical complication of graft of urinary organ	0.198	0.801	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.198	0.802	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.198	0.802	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.198	0.802	0.000
T82.3 Mechanical complication of other vascular grafts	0.198	0.802	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.198	0.802	0.000
N23 Unspecified renal colic	0.198	0.802	0.000
N21 Calculus of lower urinary tract	0.198	0.802	0.000
S19 Other and unspecified injuries of neck	0.198	0.802	0.000
S17 Crushing injury of neck	0.198	0.802	0.000
S15 Injury of blood vessels at neck level	0.198	0.802	0.000
S14 Injury of nerves and spinal cord at neck level	0.198	0.802	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.198	0.802	0.000
S11 Open wound of neck	0.198	0.802	0.000
S18 Traumatic amputation at neck level	0.198	0.802	0.000
S16 Injury of muscle and tendon at neck level	0.198	0.802	0.000
S32.4 Fracture of acetabulum	0.197	0.802	0.000
I34 Nonrheumatic mitral valve disorders	0.197	0.803	0.000
S72 Fracture of femur	0.197	0.803	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.197	0.803	0.000
S79 Other and unspecified injuries of hip and thigh	0.196	0.803	0.000
J00-J06 Acute upper respiratory infections	0.012	0.804	0.185
T83.1 Mechanical complication of other urinary devices and implants	0.196	0.804	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.195	0.804	0.000
T86.4 Liver transplant failure and rejection	0.195	0.804	0.000
T86.3 Heart-lung transplant failure and rejection	0.195	0.804	0.000
T86.2 Heart transplant failure and rejection	0.195	0.804	0.000
T86.0 Bone-marrow transplant rejection	0.195	0.804	0.000
N18 Chronic renal failure	0.195	0.805	0.000
S78 Traumatic amputation of hip and thigh	0.195	0.805	0.000
S77 Crushing injury of hip and thigh	0.195	0.805	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.195	0.805	0.000
S75 Injury of blood vessels at hip and thigh level	0.195	0.805	0.000
S74 Injury of nerves at hip and thigh level	0.195	0.805	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.195	0.805	0.000
T93.0 Sequelae of open wound of lower limb	0.194	0.806	0.000
S32.01 Fracture of lumbar vertebra (open)	0.192	0.808	0.000
J60-J70 Lung diseases due to external agents	0.020	0.809	0.171
S22.30 Fracture of rib (closed)	0.191	0.809	0.000
S27.9 Injury of unspecified intrathoracic organ	0.190	0.810	0.000
S27.8 Injury of other specified intrathoracic organs	0.190	0.810	0.000
S27.7 Multiple injuries of intrathoracic organs	0.190	0.810	0.000
S27.6 Injury of pleura	0.190	0.810	0.000
S27.5 Injury of thoracic trachea	0.190	0.810	0.000
S27.4 Injury of bronchus	0.190	0.810	0.000
S27.3 Other injuries of lung	0.190	0.810	0.000
S27.2 Traumatic heamopneumothorax	0.190	0.810	0.000
S27.1 Traumatic haemothorax	0.190	0.810	0.000
S92.3 Fracture of metatarsal bone	0.190	0.810	0.000
I50 Heart failure	0.190	0.810	0.000
I33 Acute and subacute endocarditis	0.190	0.810	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.190	0.810	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.190	0.810	0.000
S22.0 Fracture of thoracic vertebra	0.189	0.811	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.189	0.811	0.000
I30 Acute pericarditis	0.188	0.811	0.000
S61.0 Open wound of finger(s) without damage to nail	0.188	0.812	0.000
N20.0 Calculus of kidney	0.188	0.812	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.188	0.812	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.188	0.812	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.188	0.812	0.000
T85.2 Mechanical complication of intraocular lens	0.187	0.812	0.000
S32.30 Fracture of ilium (closed)	0.187	0.813	0.000
I46.9 Cardiac arrest, unspecified	0.187	0.813	0.000
T25 Burn and corrosion of ankle and foot	0.187	0.813	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.187	0.813	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.187	0.813	0.000
T21 Burn and corrosion of trunk	0.187	0.813	0.000
T20 Burn and corrosion of head and neck	0.187	0.813	0.000
T06 Other injuries involving multiple body regions, not elsewhere classified	0.186	0.814	0.000
T05 Traumatic amputations involving multiple body regions	0.186	0.814	0.000
T04 Crushing injuries involving multiple body regions	0.186	0.814	0.000
T03 Dislocations, sprains and strains involving multiple body regions	0.186	0.814	0.000
T01 Open wounds involving multiple body regions	0.186	0.814	0.000
T00 Superficial injuries involving multiple body regions	0.186	0.814	0.000
T07 Unspecified multiple injuries	0.186	0.814	0.000
T14.9 Injury, unspecified	0.186	0.814	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.186	0.814	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.186	0.814	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.186	0.814	0.000
S12.1 Fracture of second cervical vertebra	0.185	0.815	0.000
S30.1 Contusion of abdominal wall	0.185	0.815	0.000
N17 Acute renal failure	0.185	0.815	0.000
N21.0 Calculus in bladder	0.185	0.815	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.184	0.816	0.000
S22.41 Multiple fractures of ribs (open)	0.184	0.816	0.000
T93.2 Sequelae of other fractures of lower limb	0.183	0.817	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.183	0.817	0.000
S40-S49 Injuries to the shoulder and upper arm	0.183	0.817	0.000
T78.9 Adverse effect, unspecified	0.182	0.817	0.000
T78.8 Other adverse effects, not elsewhere classified	0.182	0.817	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.182	0.817	0.000
S99.9 Unspecified injury of ankle and foot	0.182	0.817	0.000
S92.2 Fracture of other tarsal bone(s)	0.182	0.818	0.000
I34.1 Mitral (valve) prolapse	0.182	0.818	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.182	0.818	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.181	0.819	0.000
I45 Other conduction disorders	0.181	0.819	0.000
N42 Other disorders of prostate	0.181	0.819	0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.180	0.820	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.179	0.821	0.000
I50.9 Heart failure, unspecified	0.179	0.821	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.178	0.822	0.000
I37 Pulmonary valve disorders	0.177	0.823	0.000
S71.1 Open wound of thigh	0.177	0.823	0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.025	0.823	0.152
J92 Pleural plaque	0.005	0.823	0.172
T93.9 Sequelae of unspecified injury of lower limb	0.176	0.823	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.176	0.823	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.176	0.823	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.176	0.823	0.000
T93.1 Sequelae of fracture of femur	0.176	0.823	0.000
S32.51 Fracture of pubis (open)	0.176	0.824	0.000
I72 Other aneurysm	0.175	0.825	0.000
I35 Nonrheumatic aortic valve disorders	0.174	0.826	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.174	0.826	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.173	0.827	0.000
S10.9 Superficial injury of neck, part unspecified	0.173	0.827	0.000
N10-N16 Renal tubulo-interstitial diseases	0.173	0.827	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.173	0.827	0.000
I74 Arterial embolism and thrombosis	0.172	0.828	0.000
I71.0 Dissection of aorta [any part]	0.172	0.828	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.171	0.828	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.171	0.829	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.171	0.829	0.000
S30.2 Contusion of external genital organs	0.171	0.829	0.000
S30.0 Contusion of lower back and pelvis	0.171	0.829	0.000
I42 Cardiomyopathy	0.171	0.829	0.000
T28 Burn and corrosion of other internal organs	0.171	0.829	0.000
T27 Burn and corrosion of respiratory tract	0.171	0.829	0.000
T26 Burn and corrosion confined to eye and adnexa	0.171	0.829	0.000
T35 Frostbite involving multiple body regions and unspecified frostbite	0.171	0.829	0.000
T34 Frostbite with tissue necrosis	0.171	0.829	0.000
T33 Superficial frostbite	0.171	0.829	0.000
I47.2 Ventricular tachycardia	0.171	0.829	0.000
T87.6 Other and unspecified complications of amputation stump	0.170	0.829	0.000
T87.5 Necrosis of amputation stump	0.170	0.829	0.000
T87.4 Infection of amputation stump	0.170	0.829	0.000
T87.3 Neuroma of amputation stump	0.170	0.829	0.000
T87.2 Complications of other reattached body part	0.170	0.829	0.000
T87.1 Complications of reattached (part of) lower extremity	0.170	0.829	0.000
T87.0 Complications of reattached (part of) upper extremity	0.170	0.829	0.000
T02.4 Fractures involving multiple regions of both upper limbs	0.169	0.830	0.000
I44.3 Other and unspecified atrioventricular block	0.170	0.830	0.000
T78.3 Angioneurotic oedema	0.169	0.830	0.000
N18.3 Chronic kidney disease, stage 3	0.170	0.830	0.000
T32 Corrosions classified according to extent of body surface involved	0.169	0.831	0.000
T30 Burn and corrosion, body region unspecified	0.169	0.831	0.000
T29 Burns and corrosions of multiple body regions	0.169	0.831	0.000
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.169	0.831	0.000
T80.6 Other serum reactions	0.169	0.831	0.000
T80.5 Anaphylactic shock due to serum	0.169	0.831	0.000
T80.4 Rh incompatibility reaction	0.169	0.831	0.000
T80.3 ABO incompatibility reaction	0.169	0.831	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.169	0.831	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.169	0.831	0.000
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.169	0.831	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.169	0.831	0.000
I52 Other heart disorders in diseases classified elsewhere	0.169	0.831	0.000
I48 Atrial fibrillation and flutter	0.169	0.831	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.169	0.831	0.000
I41 Myocarditis in diseases classified elsewhere	0.169	0.831	0.000
I40 Acute myocarditis	0.169	0.831	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.169	0.831	0.000
I36 Nonrheumatic tricuspid valve disorders	0.169	0.831	0.000
I32 Pericarditis in diseases classified elsewhere	0.169	0.831	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.168	0.832	0.000
S92.9 Fracture of foot, unspecified	0.168	0.832	0.000
S92.7 Multiple fractures of foot	0.168	0.832	0.000
S92.5 Fracture of other toe	0.168	0.832	0.000
S92.4 Fracture of great toe	0.168	0.832	0.000
S92.1 Fracture of talus	0.168	0.832	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.168	0.832	0.000
S32.31 Fracture of ilium (open)	0.167	0.833	0.000
S91.1 Open wound of toe(s) without damage to nail	0.167	0.833	0.000
T31 Burns classified according to extent of body surface involved	0.167	0.833	0.000
S80-S89 Injuries to the knee and lower leg	0.166	0.834	0.000
Y52 Agents primarily affecting the cardiovascular system	0.166	0.834	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.166	0.834	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.166	0.834	0.000
I44.6 Other and unspecified fascicular block	0.165	0.834	0.000
I44.5 Left posterior fascicular block	0.165	0.834	0.000
I44.4 Left anterior fascicular block	0.165	0.834	0.000
Y57 Other and unspecified drugs and medicaments	0.166	0.834	0.000
J02 Acute pharyngitis	0.006	0.835	0.159
I47.9 Paroxysmal tachycardia, unspecified	0.165	0.835	0.000
S22.31 Fracture of rib (open)	0.164	0.835	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.163	0.836	0.000
N20.1 Calculus of ureter	0.163	0.837	0.000
I46.1 Sudden cardiac death, so described	0.163	0.837	0.000
N17.9 Acute renal failure, unspecified	0.163	0.837	0.000
S65 Injury of blood vessels at wrist and hand level	0.163	0.837	0.000
S92.0 Fracture of calcaneus	0.163	0.837	0.000
S12.2 Fracture of other specified cervical vertebra	0.162	0.838	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.162	0.838	0.000
S68 Traumatic amputation of wrist and hand	0.162	0.838	0.000
T78.2 Anaphylactic shock, unspecified	0.162	0.838	0.000
N00-N08 Glomerular diseases	0.162	0.838	0.000
N42.2 Atrophy of prostate	0.162	0.838	0.000
S99.8 Other specified injuries of ankle and foot	0.162	0.838	0.000
S99.7 Multiple injuries of ankle and foot	0.162	0.838	0.000
N20.9 Urinary calculus, unspecified	0.162	0.838	0.000
T14.2 Fracture of unspecified body region	0.161	0.839	0.000
T14.8 Other injuries of unspecified body region	0.161	0.839	0.000
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.161	0.839	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.161	0.839	0.000
T14.5 Injury of blood vessel(s) of unspecified body region	0.161	0.839	0.000
T14.4 Injury of nerve(s) of unspecified body region	0.161	0.839	0.000
T14.3 Dislocation, sprain and strain of unspecified body region	0.161	0.839	0.000
T14.1 Open wound of unspecified body region	0.161	0.839	0.000
T14.0 Superficial injury of unspecified body region	0.161	0.839	0.000
S61.8 Open wound of other parts of wrist and hand	0.161	0.839	0.000
S12.9 Fracture of neck, part unspecified	0.161	0.839	0.000
S12.8 Fracture of other parts of neck	0.161	0.839	0.000
S12.7 Multiple fractures of cervical spine	0.161	0.839	0.000
S12.0 Fracture of first cervical vertebra	0.161	0.839	0.000
I70 Atherosclerosis	0.160	0.840	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.160	0.840	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.160	0.840	0.000
S31.5 Open wound of other and unspecified external genital organs	0.160	0.840	0.000
S31.4 Open wound of vagina and vulva	0.160	0.840	0.000
S31.3 Open wound of scrotum and testes	0.160	0.840	0.000
S31.2 Open wound of penis	0.160	0.840	0.000
S31.1 Open wound of abdominal wall	0.160	0.840	0.000
S31.0 Open wound of lower back and pelvis	0.160	0.840	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.160	0.840	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.160	0.840	0.000
S33.5 Sprain and strain of lumbar spine	0.160	0.840	0.000
S33.4 Traumatic rupture of symphysis pubis	0.160	0.840	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.160	0.840	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.160	0.840	0.000
S33.1 Dislocation of lumbar vertebra	0.160	0.840	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.160	0.840	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.160	0.840	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.160	0.840	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.160	0.840	0.000
S34.4 Injury of lumbosacral plexus	0.160	0.840	0.000
S34.3 Injury of cauda equina	0.160	0.840	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.160	0.840	0.000
S34.1 Other injury of lumbar spinal cord	0.160	0.840	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.160	0.840	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.160	0.840	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.160	0.840	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.160	0.840	0.000
S35.5 Injury of iliac blood vessels	0.160	0.840	0.000
S35.4 Injury of renal blood vessels	0.160	0.840	0.000
S35.3 Injury of portal or splenic vein	0.160	0.840	0.000
S35.2 Injury of coeliac or mesenteric artery	0.160	0.840	0.000
S35.1 Injury of inferior vena cava	0.160	0.840	0.000
S35.0 Injury of abdominal aorta	0.160	0.840	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.160	0.840	0.000
S36.8 Injury of other intra-abdominal organs	0.160	0.840	0.000
S36.7 Injury of multiple intra-abdominal organs	0.160	0.840	0.000
S36.6 Injury of rectum	0.160	0.840	0.000
S36.5 Injury of colon	0.160	0.840	0.000
S36.4 Injury of small intestine	0.160	0.840	0.000
S36.3 Injury of stomach	0.160	0.840	0.000
S36.2 Injury of pancreas	0.160	0.840	0.000
S36.1 Injury of liver or gallbladder	0.160	0.840	0.000
S36.0 Injury of spleen	0.160	0.840	0.000
S37.9 Injury of unspecified pelvic organ	0.160	0.840	0.000
S37.8 Injury of other pelvic organs	0.160	0.840	0.000
S37.7 Injury of multiple pelvic organs	0.160	0.840	0.000
S37.6 Injury of uterus	0.160	0.840	0.000
S37.5 Injury of Fallopian tube	0.160	0.840	0.000
S37.4 Injury of ovary	0.160	0.840	0.000
S37.3 Injury of urethra	0.160	0.840	0.000
S37.2 Injury of bladder	0.160	0.840	0.000
S37.1 Injury of ureter	0.160	0.840	0.000
S37.0 Injury of kidney	0.160	0.840	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.160	0.840	0.000
S38.2 Traumatic amputation of external genital organs	0.160	0.840	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.160	0.840	0.000
S38.0 Crushing injury of external genital organs	0.160	0.840	0.000
T17 Foreign body in respiratory tract	0.160	0.840	0.000
T19 Foreign body in genito-urinary tract	0.160	0.840	0.000
T15 Foreign body on external eye	0.160	0.840	0.000
T16 Foreign body in ear	0.160	0.840	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.160	0.840	0.000
N18.9 Chronic renal failure, unspecified	0.160	0.840	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.159	0.841	0.000
S92.30 Fracture of metatarsal bone (closed)	0.159	0.841	0.000
S72.3 Fracture of shaft of femur	0.159	0.841	0.000
S21.9 Open wound of thorax, part unspecified	0.159	0.841	0.000
S21.8 Open wound of other parts of thorax	0.159	0.841	0.000
S21.7 Multiple open wounds of thoracic wall	0.159	0.841	0.000
S21.2 Open wound of back wall of thorax	0.159	0.841	0.000
S21.1 Open wound of front wall of thorax	0.159	0.841	0.000
S21.0 Open wound of breast	0.159	0.841	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.159	0.841	0.000
S23.4 Sprain and strain of ribs and sternum	0.159	0.841	0.000
S23.3 Sprain and strain of thoracic spine	0.159	0.841	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.159	0.841	0.000
S23.1 Dislocation of thoracic vertebra	0.159	0.841	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations