TreeWAS – Variant ID: rs2735059

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K90.0 Coeliac disease	0.000	0.000	1.000
G35 Multiple sclerosis	0.000	0.000	1.000
E83.1 Disorders of iron metabolism	0.000	0.001	0.999
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.042	0.958
G37 Other demyelinating diseases of central nervous system	0.000	0.051	0.949
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.067	0.933
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.140	0.860
G36 Other acute disseminated demyelination	0.000	0.302	0.698
G37.5 Concentric sclerosis [Balo]	0.000	0.319	0.680
G37.4 Subacute necrotising myelitis	0.000	0.319	0.680
G37.2 Central pontine myelinolysis	0.000	0.319	0.680
G37.1 Central demyelination of corpus callosum	0.000	0.319	0.680
G37.0 Diffuse sclerosis	0.000	0.319	0.680
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.364	0.635
G36.0 Neuromyelitis optica [Devic]	0.000	0.488	0.512
G36.9 Acute disseminated demyelination, unspecified	0.000	0.499	0.500
G36.8 Other specified acute disseminated demyelination	0.000	0.499	0.500
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.499	0.500
E05.9 Thyrotoxicosis, unspecified	0.000	0.599	0.401
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.606	0.394
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.616	0.384
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.647	0.353
K90 Intestinal malabsorption	0.000	0.709	0.290
E05.5 Thyroid crisis or storm	0.000	0.718	0.282
E05.4 Thyrotoxicosis factitia	0.000	0.718	0.282
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.718	0.282
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.718	0.282
E05.8 Other thyrotoxicosis	0.000	0.740	0.260
E06 Thyroiditis	0.000	0.745	0.255
E00-E07 Disorders of thyroid gland	0.000	0.748	0.252
E06.3 Autoimmune thyroiditis	0.000	0.750	0.250
E06.9 Thyroiditis, unspecified	0.000	0.759	0.241
K90.8 Other intestinal malabsorption	0.000	0.789	0.211
K90.3 Pancreatic steatorrhoea	0.000	0.791	0.208
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.791	0.208
K90.1 Tropical sprue	0.000	0.791	0.208
K90.9 Intestinal malabsorption, unspecified	0.000	0.801	0.199
E06.5 Other chronic thyroiditis	0.000	0.805	0.195
E06.4 Drug-induced thyroiditis	0.000	0.817	0.183
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.817	0.183
E06.0 Acute thyroiditis	0.000	0.817	0.183
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.819	0.181
E00 Congenital iodine-deficiency syndrome	0.000	0.819	0.181
E06.1 Subacute thyroiditis	0.000	0.830	0.170
E07 Other disorders of thyroid	0.000	0.851	0.149
I84.9 Unspecified haemorrhoids without complication	0.147	0.853	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.858	0.142
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.862	0.138
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.870	0.130
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.870	0.130
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.870	0.130
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.870	0.130
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.870	0.130
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.870	0.130
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.870	0.130
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.870	0.130
E83 Disorders of mineral metabolism	0.000	0.872	0.128
E07.8 Other specified disorders of thyroid	0.000	0.886	0.114
M35.0 Sicca syndrome [Sjogren]	0.000	0.886	0.114
E07.1 Dyshormogenetic goitre	0.000	0.893	0.107
E07.0 Hypersecretion of calcitonin	0.000	0.893	0.107
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.893	0.107
E03 Other hypothyroidism	0.000	0.907	0.093
E83.8 Other disorders of mineral metabolism	0.000	0.908	0.092
E83.2 Disorders of zinc metabolism	0.000	0.908	0.092
E83.0 Disorders of copper metabolism	0.000	0.908	0.092
E83.3 Disorders of phosphorus metabolism	0.000	0.913	0.087
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.914	0.086
E83.5 Disorders of calcium metabolism	0.000	0.926	0.074
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.932	0.068
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.933	0.067
E03.5 Myxoedema coma	0.000	0.933	0.067
E03.4 Atrophy of thyroid (acquired)	0.000	0.933	0.067
E03.3 Postinfectious hypothyroidism	0.000	0.933	0.067
S06.3 Focal brain injury	0.000	0.934	0.066
E03.8 Other specified hypothyroidism	0.000	0.937	0.063
E07.9 Disorder of thyroid, unspecified	0.000	0.939	0.061
E03.1 Congenital hypothyroidism without goitre	0.000	0.942	0.058
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.952	0.047
E04 Other non-toxic goitre	0.000	0.963	0.037
S06 Intracranial injury	0.000	0.963	0.037
S06.5 Traumatic subdural haemorrhage	0.000	0.966	0.034
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.967	0.033
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.968	0.031
K90-K93 Other diseases of the digestive system	0.000	0.971	0.029
S06.1 Traumatic cerebral oedema	0.000	0.972	0.028
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.972	0.028
E04.0 Non-toxic diffuse goitre	0.000	0.972	0.028
E04.8 Other specified non-toxic goitre	0.000	0.973	0.027
S06.7 Intracranial injury with prolonged coma	0.000	0.973	0.027
M35 Other systemic involvement of connective tissue	0.000	0.973	0.027
S06.9 Intracranial injury, unspecified	0.000	0.974	0.026
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.975	0.025
M35.7 Hypermobility syndrome	0.000	0.976	0.024
S06.0 Concussion	0.000	0.976	0.024
S06.4 Epidural haemorrhage	0.000	0.977	0.023
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.977	0.023
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.978	0.022
E83.4 Disorders of magnesium metabolism	0.000	0.979	0.021
S06.2 Diffuse brain injury	0.000	0.979	0.021
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.979	0.021
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.979	0.021
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.021	0.979	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.979	0.021
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.979	0.020
S06.8 Other intracranial injuries	0.000	0.979	0.020
E70-E90 Metabolic disorders	0.000	0.980	0.020
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.981	0.019
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.981	0.019
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.981	0.019
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.981	0.019
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.981	0.019
M35.5 Multifocal fibrosclerosis	0.000	0.981	0.019
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.981	0.019
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.981	0.019
E40-E46 Malnutrition	0.000	0.981	0.019
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.981	0.019
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.982	0.018
M35.8 Other specified systemic involvement of connective tissue	0.000	0.982	0.018
E89.2 Postprocedural hypoparathyroidism	0.000	0.982	0.018
S06.01 Concussion (with open intracranial wound)	0.000	0.983	0.017
E46 Unspecified protein-energy malnutrition	0.000	0.983	0.017
M35.1 Other overlap syndromes	0.000	0.983	0.017
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.983	0.017
M35.2 Behcet's disease	0.000	0.983	0.016
E03.9 Hypothyroidism, unspecified	0.000	0.984	0.016
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.984	0.015
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.984	0.015
K93.1 Megacolon in Chagas' disease	0.000	0.984	0.015
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.984	0.015
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.985	0.015
E77 Disorders of glycoprotein metabolism	0.000	0.985	0.015
E76 Disorders of glycosaminoglycan metabolism	0.000	0.985	0.015
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.985	0.015
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.985	0.015
S06.00 Concussion (without open intracranial wound)	0.000	0.986	0.014
N76 Other inflammation of vagina and vulva	0.000	0.986	0.014
E70 Disorders of aromatic amino-acid metabolism	0.000	0.986	0.014
E89.4 Postprocedural ovarian failure	0.000	0.986	0.014
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.986	0.014
E89.1 Postprocedural hypoinsulinaemia	0.000	0.986	0.014
E84 Cystic fibrosis	0.000	0.986	0.014
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.986	0.014
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.986	0.014
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.986	0.014
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.986	0.013
E45 Retarded development following protein-energy malnutrition	0.000	0.986	0.013
E43 Unspecified severe protein-energy malnutrition	0.000	0.986	0.013
E42 Marasmic kwashiorkor	0.000	0.986	0.013
E41 Nutritional marasmus	0.000	0.986	0.013
E40 Kwashiorkor	0.000	0.986	0.013
E72 Other disorders of amino-acid metabolism	0.000	0.986	0.013
N76.8 Other specified inflammation of vagina and vulva	0.000	0.986	0.014
N76.3 Subacute and chronic vulvitis	0.000	0.986	0.013
N76.2 Acute vulvitis	0.000	0.986	0.013
E73 Lactose intolerance	0.000	0.987	0.013
E04.9 Non-toxic goitre, unspecified	0.000	0.987	0.013
E79 Disorders of purine and pyrimidine metabolism	0.000	0.987	0.013
N76.0 Acute vaginitis	0.000	0.987	0.013
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.987	0.013
E74 Other disorders of carbohydrate metabolism	0.000	0.987	0.013
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.987	0.013
N76.4 Abscess of vulva	0.000	0.987	0.013
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.988	0.012
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.988	0.012
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.988	0.012
E88 Other metabolic disorders	0.000	0.988	0.012
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.988	0.012
E27.1 Primary adrenocortical insufficiency	0.000	0.989	0.011
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.989	0.011
E84.9 Cystic fibrosis, unspecified	0.000	0.989	0.011
E04.2 Non-toxic multinodular goitre	0.000	0.989	0.011
N76.5 Ulceration of vagina	0.000	0.989	0.011
E75.5 Other lipid storage disorders	0.000	0.989	0.011
E71.3 Disorders of fatty-acid metabolism	0.000	0.989	0.011
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.989	0.011
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.989	0.011
E71.0 Maple-syrup-urine disease	0.000	0.989	0.011
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.989	0.011
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.989	0.011
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.989	0.011
E76.2 Other mucopolysaccharidoses	0.000	0.989	0.011
E76.1 Mucopolysaccharidosis, type II	0.000	0.989	0.011
E76.0 Mucopolysaccharidosis, type I	0.000	0.989	0.011
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.989	0.011
E77.8 Other disorders of glycoprotein metabolism	0.000	0.989	0.011
E77.1 Defects in glycoprotein degradation	0.000	0.989	0.011
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.989	0.011
E89.5 Postprocedural testicular hypofunction	0.000	0.989	0.010
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.989	0.011
I71 Aortic aneurysm and dissection	0.000	0.989	0.011
N76.1 Subacute and chronic vaginitis	0.000	0.989	0.010
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.989	0.010
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.989	0.010
E70.2 Disorders of tyrosine metabolism	0.000	0.989	0.010
E70.1 Other hyperphenylalaninaemias	0.000	0.989	0.010
E70.0 Classical phenylketonuria	0.000	0.989	0.010
E84.8 Cystic fibrosis with other manifestations	0.000	0.990	0.010
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.990	0.010
E75.6 Lipid storage disorder, unspecified	0.000	0.990	0.010
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.990	0.010
E75.3 Sphingolipidosis, unspecified	0.000	0.990	0.010
E75.1 Other gangliosidosis	0.000	0.990	0.010
E75.0 GM2 gangliosidosis	0.000	0.990	0.010
K50.9 Crohn's disease, unspecified	0.010	0.990	0.000
E70.3 Albinism	0.000	0.990	0.010
E80.6 Other disorders of bilirubin metabolism	0.000	0.990	0.010
E44.1 Mild protein-energy malnutrition	0.000	0.990	0.010
E44.0 Moderate protein-energy malnutrition	0.000	0.990	0.010
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.990	0.010
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.990	0.010
E72.5 Disorders of glycine metabolism	0.000	0.990	0.010
E72.4 Disorders of ornithine metabolism	0.000	0.990	0.010
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.990	0.010
E72.2 Disorders of urea cycle metabolism	0.000	0.990	0.010
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.990	0.010
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.990	0.010
E72.0 Disorders of amino-acid transport	0.000	0.990	0.010
E73.8 Other lactose intolerance	0.000	0.990	0.009
E73.1 Secondary lactase deficiency	0.000	0.990	0.009
E73.0 Congenital lactase deficiency	0.000	0.990	0.009
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.990	0.009
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.990	0.009
E79.1 Lesch-Nyhan syndrome	0.000	0.990	0.009
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.990	0.009
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.990	0.009
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.990	0.009
E74.2 Disorders of galactose metabolism	0.000	0.990	0.009
E74.1 Disorders of fructose metabolism	0.000	0.990	0.009
E80.1 Porphyria cutanea tarda	0.000	0.990	0.009
E88.9 Metabolic disorder, unspecified	0.000	0.991	0.009
K91.1 Postgastric surgery syndromes	0.000	0.991	0.009
E74.0 Glycogen storage disease	0.000	0.991	0.009
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.991	0.009
J15.1 Pneumonia due to Pseudomonas	0.009	0.991	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.991	0.009
E80.5 Crigler-Najjar syndrome	0.000	0.991	0.009
E80.3 Defects of catalase and peroxydase	0.000	0.991	0.009
E80.0 Hereditary erythropoietic porphyria	0.000	0.991	0.009
K91.5 Postcholecystectomy syndrome	0.000	0.991	0.009
J15 Bacterial pneumonia, not elsewhere classified	0.009	0.991	0.000
E89.3 Postprocedural hypopituitarism	0.000	0.991	0.009
E88.3 Tumour lysis syndrome	0.000	0.991	0.009
S06.80 Other intracranial injuries (without open intracranial wound)	0.000	0.991	0.008
E75.2 Other sphingolipidosis	0.000	0.991	0.009
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.006	0.991	0.003
E27 Other disorders of adrenal gland	0.000	0.991	0.009
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.991	0.008
E88.2 Lipomatosis, not elsewhere classified	0.000	0.991	0.008
J15.0 Pneumonia due to Klebsiella pneumoniae	0.009	0.991	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.991	0.008
E20-E35 Disorders of other endocrine glands	0.000	0.992	0.008
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.992	0.008
E88.8 Other specified metabolic disorders	0.000	0.992	0.008
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.992	0.008
J15.2 Pneumonia due to staphylococcus	0.008	0.992	0.000
G63.2 Diabetic polyneuropathy	0.008	0.992	0.000
J15.4 Pneumonia due to other streptococci	0.008	0.992	0.000
E50-E64 Other nutritional deficiencies	0.000	0.992	0.008
G63 Polyneuropathy in diseases classified elsewhere	0.007	0.992	0.001
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.992	0.008
Z41 Procedures for purposes other than remedying health state	0.008	0.992	0.000
E04.1 Non-toxic single thyroid nodule	0.000	0.992	0.008
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.992	0.008
E73.9 Lactose intolerance, unspecified	0.000	0.992	0.008
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.992	0.008
G60.0 Hereditary motor and sensory neuropathy	0.008	0.992	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.992	0.008
E80.2 Other porphyria	0.000	0.992	0.008
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.992	0.008
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.992	0.008
E65-E68 Obesity and other hyperalimentation	0.000	0.992	0.008
G60 Hereditary and idiopathic neuropathy	0.006	0.992	0.001
N76.6 Ulceration of vulva	0.000	0.992	0.008
E20 Hypoparathyroidism	0.000	0.992	0.007
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.007	0.993	0.000
C50.9 Breast, unspecified	0.007	0.993	0.000
J15.5 Pneumonia due to Escherichia coli	0.007	0.993	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.993	0.007
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.993	0.007
E25 Adrenogenital disorders	0.000	0.993	0.007
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.993	0.007
I73.9 Peripheral vascular disease, unspecified	0.000	0.993	0.007
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.993	0.007
J15.8 Other bacterial pneumonia	0.007	0.993	0.000
K51.2 Ulcerative (chronic) proctitis	0.007	0.993	0.000
K50 Crohn's disease [regional enteritis]	0.007	0.993	0.000
K50.8 Other Crohn's disease	0.007	0.993	0.000
G61 Inflammatory polyneuropathy	0.006	0.993	0.001
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.007	0.993	0.000
E20.9 Hypoparathyroidism, unspecified	0.000	0.993	0.007
E85 Amyloidosis	0.001	0.993	0.006
E23 Hypofunction and other disorders of pituitary gland	0.000	0.993	0.007
J15.3 Pneumonia due to streptococcus, group B	0.007	0.993	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.993	0.007
Z41.8 Other procedures for purposes other than remedying health state	0.007	0.993	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.993	0.007
R31 Unspecified haematuria	0.007	0.993	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.993	0.007
E51 Thiamine deficiency	0.000	0.993	0.006
E27.5 Adrenomedullary hyperfunction	0.000	0.993	0.006
E27.0 Other adrenocortical overactivity	0.000	0.993	0.006
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.993	0.007
G64 Other disorders of peripheral nervous system	0.004	0.993	0.002
I71.0 Dissection of aorta [any part]	0.000	0.994	0.006
G61.0 Guillain-Barre syndrome	0.006	0.994	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.994	0.006
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.994	0.006
E32 Diseases of thymus	0.000	0.994	0.006
E31 Polyglandular dysfunction	0.000	0.994	0.006
E30 Disorders of puberty, not elsewhere classified	0.000	0.994	0.006
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.994	0.006
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.994	0.006
E23.6 Other disorders of pituitary gland	0.000	0.994	0.006
E56 Other vitamin deficiencies	0.000	0.994	0.006
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.994	0.006
E63 Other nutritional deficiencies	0.000	0.994	0.006
E50 Vitamin A deficiency	0.000	0.994	0.006
E60 Dietary zinc deficiency	0.000	0.994	0.006
E59 Dietary selenium deficiency	0.000	0.994	0.006
E52 Niacin deficiency [pellagra]	0.000	0.994	0.006
G62 Other polyneuropathies	0.003	0.994	0.003
G63.8 Polyneuropathy in other diseases classified elsewhere	0.005	0.994	0.001
G63.6 Polyneuropathy in other musculoskeletal disorders	0.005	0.994	0.001
G63.5 Polyneuropathy in systemic connective tissue disorders	0.005	0.994	0.001
G63.4 Polyneuropathy in nutritional deficiency	0.005	0.994	0.001
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.005	0.994	0.001
G63.1 Polyneuropathy in neoplastic disease	0.005	0.994	0.001
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.005	0.994	0.001
Z41.3 Ear piercing	0.006	0.994	0.000
Z41.0 Hair transplant	0.006	0.994	0.000
E55 Vitamin D deficiency	0.000	0.994	0.006
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.006	0.994	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.994	0.006
E27.2 Addisonian crisis	0.000	0.994	0.006
I73 Other peripheral vascular diseases	0.000	0.994	0.006
I72.4 Aneurysm of artery of lower extremity	0.000	0.994	0.006
E67 Other hyperalimentation	0.000	0.994	0.006
E68 Sequelae of hyperalimentation	0.000	0.994	0.006
G60.3 Idiopathic progressive neuropathy	0.005	0.994	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.005	0.994	0.001
G60.1 Refsum's disease	0.005	0.994	0.001
I72 Other aneurysm	0.000	0.994	0.006
G30-G32 Other degenerative diseases of the nervous system	0.000	0.994	0.006
E26 Hyperaldosteronism	0.000	0.994	0.006
E20.8 Other hypoparathyroidism	0.000	0.994	0.005
E20.1 Pseudohypoparathyroidism	0.000	0.994	0.005
E20.0 Idiopathic hypoparathyroidism	0.000	0.994	0.005
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.005	0.994	0.001
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.994	0.006
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.994	0.006
E54 Ascorbic acid deficiency	0.000	0.994	0.005
Chapter VI Diseases of the nervous system	0.000	0.994	0.006
J15.9 Bacterial pneumonia, unspecified	0.005	0.994	0.000
G61.8 Other inflammatory polyneuropathies	0.005	0.995	0.000
M35.3 Polymyalgia rheumatica	0.000	0.995	0.005
E25.9 Adrenogenital disorder, unspecified	0.000	0.995	0.005
E25.8 Other adrenogenital disorders	0.000	0.995	0.005
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.995	0.005
E23.7 Disorder of pituitary gland, unspecified	0.000	0.995	0.005
E51.2 Wernicke's encephalopathy	0.000	0.995	0.005
E85.8 Other amyloidosis	0.001	0.995	0.005
G61.1 Serum neuropathy	0.005	0.995	0.001
E29 Testicular dysfunction	0.000	0.995	0.005
E58 Dietary calcium deficiency	0.000	0.995	0.005
E34 Other endocrine disorders	0.000	0.995	0.005
G61.9 Inflammatory polyneuropathy, unspecified	0.005	0.995	0.001
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.995	0.005
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.995	0.005
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.995	0.005
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.995	0.005
E23.1 Drug-induced hypopituitarism	0.000	0.995	0.005
G31.2 Degeneration of nervous system due to alcohol	0.000	0.995	0.005
G31.8 Other specified degenerative diseases of nervous system	0.000	0.995	0.005
E80.4 Gilbert's syndrome	0.000	0.995	0.005
G60.8 Other hereditary and idiopathic neuropathies	0.004	0.995	0.001
I72.9 Aneurysm of unspecified site	0.000	0.995	0.005
S46 Injury of muscle and tendon at shoulder and upper arm level	0.000	0.995	0.005
E53 Deficiency of other B group vitamins	0.000	0.995	0.005
E51.9 Thiamine deficiency, unspecified	0.000	0.995	0.005
E51.8 Other manifestations of thiamine deficiency	0.000	0.995	0.005
E51.1 Beriberi	0.000	0.995	0.005
Z41.2 Routine and ritual circumcision	0.005	0.995	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.995	0.005
I72.1 Aneurysm of artery of upper extremity	0.000	0.995	0.005
G31.0 Circumscribed brain atrophy	0.000	0.995	0.005
K50.1 Crohn's disease of large intestine	0.005	0.995	0.000
E56.1 Deficiency of vitamin K	0.000	0.995	0.005
E30.9 Disorder of puberty, unspecified	0.000	0.995	0.005
E30.8 Other disorders of puberty	0.000	0.995	0.005
E30.1 Precocious puberty	0.000	0.995	0.005
E30.0 Delayed puberty	0.000	0.995	0.005
E31.9 Polyglandular dysfunction, unspecified	0.000	0.995	0.005
E31.8 Other polyglandular dysfunction	0.000	0.995	0.005
E31.1 Polyglandular hyperfunction	0.000	0.995	0.005
E31.0 Autoimmune polyglandular failure	0.000	0.995	0.005
E32.9 Disease of thymus, unspecified	0.000	0.995	0.005
E32.8 Other diseases of thymus	0.000	0.995	0.005
E32.1 Abscess of thymus	0.000	0.995	0.005
E32.0 Persistent hyperplasia of thymus	0.000	0.995	0.005
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.995	0.005
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.995	0.005
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.995	0.005
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.995	0.005
E56.9 Vitamin deficiency, unspecified	0.000	0.995	0.005
E56.8 Deficiency of other vitamins	0.000	0.995	0.005
E56.0 Deficiency of vitamin E	0.000	0.995	0.005
I70 Atherosclerosis	0.000	0.995	0.005
S46.0 Injury of tendon of the rotator cuff of shoulder	0.000	0.995	0.005
E50.9 Vitamin A deficiency, unspecified	0.000	0.995	0.004
E50.8 Other manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.995	0.004
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.995	0.004
E50.5 Vitamin A deficiency with night blindness	0.000	0.995	0.004
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.995	0.004
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.995	0.004
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.995	0.004
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.995	0.004
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.995	0.004
E63.9 Nutritional deficiency, unspecified	0.000	0.995	0.004
E63.8 Other specified nutritional deficiencies	0.000	0.995	0.004
E63.1 Imbalance of constituents of food intake	0.000	0.995	0.004
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.995	0.004
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.995	0.004
E64.8 Sequelae of other nutritional deficiencies	0.000	0.995	0.004
E64.3 Sequelae of rickets	0.000	0.995	0.004
E64.2 Sequelae of vitamin C deficiency	0.000	0.995	0.004
E64.1 Sequelae of vitamin A deficiency	0.000	0.995	0.004
E64.0 Sequelae of protein-energy malnutrition	0.000	0.995	0.004
G62.2 Polyneuropathy due to other toxic agents	0.002	0.995	0.002
E55.0 Rickets, active	0.000	0.995	0.004
E23.2 Diabetes insipidus	0.000	0.995	0.005
S49 Other and unspecified injuries of shoulder and upper arm	0.000	0.995	0.005
G62.1 Alcoholic polyneuropathy	0.001	0.995	0.003
E65 Localised adiposity	0.000	0.995	0.004
E27.9 Disorder of adrenal gland, unspecified	0.000	0.995	0.004
K51 Ulcerative colitis	0.005	0.995	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.995	0.005
I72.8 Aneurysm of other specified arteries	0.000	0.995	0.005
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.000	0.995	0.005
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.995	0.004
G47.9 Sleep disorder, unspecified	0.000	0.995	0.005
E67.8 Other specified hyperalimentation	0.000	0.996	0.004
E67.3 Hypervitaminosis D	0.000	0.996	0.004
E67.2 Megavitamin-B6 syndrome	0.000	0.996	0.004
E67.1 Hypercarotenaemia	0.000	0.996	0.004
E67.0 Hypervitaminosis A	0.000	0.996	0.004
I77.2 Rupture of artery	0.000	0.996	0.004
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.996	0.004
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.996	0.004
E86 Volume depletion	0.000	0.996	0.004
B37.9 Candidiasis, unspecified	0.000	0.996	0.004
E26.8 Other hyperaldosteronism	0.000	0.996	0.004
E26.1 Secondary hyperaldosteronism	0.000	0.996	0.004
E23.0 Hypopituitarism	0.000	0.996	0.004
K51.0 Ulcerative (chronic) enterocolitis	0.004	0.996	0.000
I77 Other disorders of arteries and arterioles	0.000	0.996	0.004
S46.3 Injury of muscle and tendon of triceps	0.000	0.996	0.004
I79.1 Aortitis in diseases classified elsewhere	0.000	0.996	0.004
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.996	0.004
F01.9 Vascular dementia, unspecified	0.000	0.996	0.004
E34.9 Endocrine disorder, unspecified	0.000	0.996	0.004
G62.9 Polyneuropathy, unspecified	0.000	0.996	0.004
I72.2 Aneurysm of renal artery	0.000	0.996	0.004
E26.9 Hyperaldosteronism, unspecified	0.000	0.996	0.004
E85.3 Secondary systemic amyloidosis	0.001	0.996	0.003
G62.0 Drug-induced polyneuropathy	0.002	0.996	0.002
I70.8 Atherosclerosis of other arteries	0.000	0.996	0.004
E24 Cushing's syndrome	0.000	0.996	0.004
E28 Ovarian dysfunction	0.000	0.996	0.004
E29.8 Other testicular dysfunction	0.000	0.996	0.004
E29.0 Testicular hyperfunction	0.000	0.996	0.004
E34.5 Androgen resistance syndrome	0.000	0.996	0.004
E34.4 Constitutional tall stature	0.000	0.996	0.004
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.996	0.004
E34.1 Other hypersecretion of intestinal hormones	0.000	0.996	0.004
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.996	0.004
E26.0 Primary hyperaldosteronism	0.000	0.996	0.004
E85.4 Organ-limited amyloidosis	0.001	0.996	0.003
K50-K52 Noninfective enteritis and colitis	0.004	0.996	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.000	0.996	0.004
I74 Arterial embolism and thrombosis	0.000	0.996	0.004
E29.9 Testicular dysfunction, unspecified	0.000	0.996	0.004
E53.1 Pyridoxine deficiency	0.000	0.996	0.004
E53.0 Riboflavin deficiency	0.000	0.996	0.004
G00-G09 Inflammatory diseases of the central nervous system	0.000	0.996	0.004
G62.8 Other specified polyneuropathies	0.003	0.996	0.001
S49.8 Other specified injuries of shoulder and upper arm	0.000	0.996	0.004
E22 Hyperfunction of pituitary gland	0.000	0.996	0.004
E34.3 Short stature, not elsewhere classified	0.000	0.996	0.004
E34.0 Carcinoid syndrome	0.000	0.996	0.004
I74.8 Embolism and thrombosis of other arteries	0.000	0.996	0.004
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.996	0.004
G30 Alzheimer's disease	0.000	0.996	0.004
K51.1 Ulcerative (chronic) ileocolitis	0.004	0.996	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.000	0.996	0.004
I73.8 Other specified peripheral vascular diseases	0.000	0.996	0.003
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.996	0.004
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.996	0.003
E53.9 Vitamin B deficiency, unspecified	0.000	0.996	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations