TreeWAS – Variant ID: rs2777491

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Y42.5 Other oestrogens and progestogens	0.031	0.969	0.000
C56 Malignant neoplasm of ovary	0.000	0.975	0.025
C34.1 Upper lobe, bronchus or lung	0.000	0.983	0.017
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.984	0.016
N70.1 Chronic salpingitis and oophoritis	0.014	0.986	0.000
C51-C58 Malignant neoplasms of female genital organs	0.000	0.987	0.013
M50.3 Other cervical disk degeneration	0.012	0.988	0.000
C54 Malignant neoplasm of corpus uteri	0.000	0.988	0.012
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.988	0.011
C54.9 Corpus uteri, unspecified	0.000	0.989	0.011
Z29.1 Prophylactic immunotherapy	0.010	0.990	0.000
C53 Malignant neoplasm of cervix uteri	0.000	0.990	0.010
C57.0 Fallopian tube	0.000	0.990	0.010
C58 Malignant neoplasm of placenta	0.000	0.990	0.009
D09.0 Bladder	0.009	0.990	0.000
C57.9 Female genital organ, unspecified	0.000	0.991	0.009
C54.1 Endometrium	0.000	0.991	0.009
H04 Disorders of lachrymal system	0.000	0.991	0.009
C51 Malignant neoplasm of vulva	0.000	0.991	0.009
C54.8 Overlapping lesion of corpus uteri	0.000	0.991	0.009
C54.3 Fundus uteri	0.000	0.991	0.009
C54.2 Myometrium	0.000	0.991	0.009
C54.0 Isthmus uteri	0.000	0.991	0.009
C57.8 Overlapping lesion of female genital organs	0.000	0.991	0.008
C57.7 Other specified female genital organs	0.000	0.991	0.008
C57.4 Uterine adnexa, unspecified	0.000	0.991	0.008
C57.3 Parametrium	0.000	0.991	0.008
C57.2 Round ligament	0.000	0.991	0.008
C57.1 Broad ligament	0.000	0.991	0.008
C53.0 Endocervix	0.000	0.992	0.008
H04.3 Acute and unspecified inflammation of lachrymal passages	0.000	0.992	0.008
C52 Malignant neoplasm of vagina	0.000	0.992	0.007
H04.8 Other disorders of lachrymal system	0.000	0.992	0.008
C53.8 Overlapping lesion of cervix uteri	0.000	0.992	0.007
C53.1 Exocervix	0.000	0.992	0.007
O20.9 Haemorrhage in early pregnancy, unspecified	0.007	0.993	0.000
S19.9 Unspecified injury of neck	0.007	0.993	0.000
O20.8 Other haemorrhage in early pregnancy	0.007	0.993	0.000
C53.9 Cervix uteri, unspecified	0.000	0.993	0.007
I42.9 Cardiomyopathy, unspecified	0.000	0.993	0.007
H04.4 Chronic inflammation of lachrymal passages	0.000	0.993	0.007
C51.0 Labium majus	0.000	0.993	0.007
D47.1 Chronic myeloproliferative disease	0.007	0.993	0.000
H04.2 Epiphora	0.000	0.993	0.007
H04.6 Other changes in lachrymal passages	0.000	0.993	0.007
N70 Salpingitis and oophoritis	0.007	0.993	0.000
Z29 Need for other prophylactic measures	0.007	0.993	0.000
H04.0 Dacryoadenitis	0.000	0.993	0.006
Z29.0 Isolation	0.007	0.993	0.000
C51.8 Overlapping lesion of vulva	0.000	0.993	0.006
C51.2 Clitoris	0.000	0.993	0.006
C51.1 Labium minus	0.000	0.993	0.006
O20 Haemorrhage in early pregnancy	0.006	0.994	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.000	0.994	0.006
N70.0 Acute salpingitis and oophoritis	0.005	0.994	0.000
H04.9 Disorder of lachrymal system, unspecified	0.000	0.994	0.005
K74.6 Other and unspecified cirrhosis of liver	0.000	0.995	0.005
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.995	0.005
Z29.8 Other specified prophylactic measures	0.005	0.995	0.000
Z29.9 Prophylactic measure, unspecified	0.005	0.995	0.000
I47.1 Supraventricular tachycardia	0.005	0.995	0.000
C51.9 Vulva, unspecified	0.000	0.995	0.005
S19 Other and unspecified injuries of neck	0.005	0.995	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.995	0.005
O73.0 Retained placenta, without haemorrhage	0.005	0.995	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.005	0.995	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
K74.0 Hepatic fibrosis	0.000	0.995	0.005
D09 Carcinoma in situ of other and unspecified sites	0.004	0.995	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.995	0.004
O20.0 Threatened abortion	0.004	0.995	0.000
N61 Inflammatory disorders of breast	0.000	0.996	0.004
K75.8 Other specified inflammatory liver diseases	0.000	0.996	0.004
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.004	0.996	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.004	0.996	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.996	0.004
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.004	0.996	0.000
S43.1 Dislocation of acromioclavicular joint	0.004	0.996	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.996	0.004
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
S72.40 Fracture of lower end of femur (closed)	0.004	0.996	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.996	0.004
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.996	0.004
K74.1 Hepatic sclerosis	0.000	0.996	0.004
S19.7 Multiple injuries of neck	0.004	0.996	0.000
S43.0 Dislocation of shoulder joint	0.004	0.996	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.004	0.996	0.000
Y52 Agents primarily affecting the cardiovascular system	0.004	0.996	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.996	0.004
I42.0 Dilated cardiomyopathy	0.000	0.996	0.004
K74.3 Primary biliary cirrhosis	0.000	0.996	0.004
L53.9 Erythematous condition, unspecified	0.000	0.996	0.004
Y52.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.004	0.996	0.000
D09.1 Other and unspecified urinary organs	0.003	0.996	0.000
L85.8 Other specified epidermal thickening	0.000	0.996	0.004
I47 Paroxysmal tachycardia	0.004	0.996	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.004	0.996	0.000
D09.9 Carcinoma in situ, unspecified	0.003	0.996	0.000
D09.7 Carcinoma in situ of other specified sites	0.003	0.996	0.000
D09.3 Thyroid and other endocrine glands	0.003	0.996	0.000
D09.2 Eye	0.003	0.996	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.003	0.997	0.000
S10-S19 Injuries to the neck	0.003	0.997	0.000
I42 Cardiomyopathy	0.000	0.997	0.003
S13.1 Dislocation of cervical vertebra	0.003	0.997	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.003	0.997	0.000
Z94.0 Kidney transplant status	0.003	0.997	0.000
Z29.2 Other prophylactic chemotherapy	0.003	0.997	0.000
S19.8 Other specified injuries of neck	0.003	0.997	0.000
N99.1 Postprocedural urethral stricture	0.003	0.997	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
N99.0 Postprocedural renal failure	0.003	0.997	0.000
S13.5 Sprain and strain of thyroid region	0.003	0.997	0.000
S13.3 Multiple dislocations of neck	0.003	0.997	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.003	0.997	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.997	0.003
S13.4 Sprain and strain of cervical spine	0.003	0.997	0.000
Y42.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.000	0.997	0.003
Q51.3 Bicornate uterus	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
K50.1 Crohn's disease of large intestine	0.003	0.997	0.000
Y52.7 Peripheral vasodilators	0.003	0.997	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
Y42.4 Oral contraceptives	0.003	0.997	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.997	0.000
K75 Other inflammatory liver diseases	0.000	0.997	0.003
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.003	0.997	0.000
Y42.2 Antithyroid drugs	0.003	0.997	0.000
K91.4 Colostomy and enterostomy malfunction	0.000	0.997	0.003
E89.3 Postprocedural hypopituitarism	0.000	0.997	0.003
Y52.8 Antivaricose drugs, including sclerosing agents	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.003	0.997	0.000
N99.2 Postprocedural adhesions of vagina	0.003	0.997	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.997	0.003
S14 Injury of nerves and spinal cord at neck level	0.003	0.997	0.000
I42.6 Alcoholic cardiomyopathy	0.000	0.997	0.003
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.997	0.003
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.003	0.997	0.000
S43.2 Dislocation of sternoclavicular joint	0.003	0.997	0.000
Y52.1 Calcium-channel blockers	0.003	0.997	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.003	0.997	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.997	0.003
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
S72.41 Fracture of lower end of femur (open)	0.003	0.997	0.000
S17 Crushing injury of neck	0.003	0.997	0.000
S15 Injury of blood vessels at neck level	0.003	0.997	0.000
S18 Traumatic amputation at neck level	0.003	0.997	0.000
S16 Injury of muscle and tendon at neck level	0.003	0.997	0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.003	0.997	0.000
I42.5 Other restrictive cardiomyopathy	0.000	0.997	0.003
I42.4 Endocardial fibroelastosis	0.000	0.997	0.003
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.997	0.003
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
N99.5 Malfunction of external stoma of urinary tract	0.003	0.997	0.000
S72.4 Fracture of lower end of femur	0.003	0.997	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.997	0.000
M62.8 Other specified disorders of muscle	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.003	0.997	0.000
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.002	0.997	0.000
K75.4 Autoimmune hepatitis	0.000	0.997	0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.003	0.997	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.997	0.000
S12 Fracture of neck	0.002	0.997	0.000
S11 Open wound of neck	0.002	0.997	0.000
I47.0 Reentry ventricular arrhythmia	0.002	0.997	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.997	0.000
Z39.2 Routine postpartum follow-up	0.002	0.997	0.000
I47.2 Ventricular tachycardia	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.002	0.998	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
C78.0 Secondary malignant neoplasm of lung	0.000	0.998	0.002
K75.2 Nonspecific reactive hepatitis	0.000	0.998	0.002
K75.1 Phlebitis of portal vein	0.000	0.998	0.002
S10 Superficial injury of neck	0.002	0.998	0.000
D10.1 Tongue	0.002	0.998	0.000
I42.2 Other hypertrophic cardiomyopathy	0.000	0.998	0.002
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.002	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.002	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.002	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.002	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.002	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.002	0.998	0.000
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.002	0.998	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.998	0.002
S10.1 Other and unspecified superficial injuries of throat	0.002	0.998	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.002	0.998	0.000
S15.8 Injury of other blood vessels at neck level	0.002	0.998	0.000
S15.7 Injury of multiple blood vessels at neck level	0.002	0.998	0.000
S15.3 Injury of internal jugular vein	0.002	0.998	0.000
S15.2 Injury of external jugular vein	0.002	0.998	0.000
S15.1 Injury of vertebral artery	0.002	0.998	0.000
S15.0 Injury of carotid artery	0.002	0.998	0.000
S17.9 Crushing injury of neck, part unspecified	0.002	0.998	0.000
S17.8 Crushing injury of other parts of neck	0.002	0.998	0.000
S17.0 Crushing injury of larynx and traches	0.002	0.998	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.002	0.998	0.000
X78.0 Home	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
R84.5 Abnormal microbiological findings	0.002	0.998	0.000
M62.88 Other specified disorders of muscle (Other)	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.000	0.998	0.002
Q51.2 Other doubling of uterus	0.002	0.998	0.000
S11.7 Multiple open wounds of neck	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
J31.0 Chronic rhinitis	0.000	0.998	0.002
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.998	0.002
S14.3 Injury of brachial plexus	0.002	0.998	0.000
Y44 Agents primarily affecting blood constituents	0.002	0.998	0.000
Q51 Congenital malformations of uterus and cervix	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
G93.6 Cerebral oedema	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
D16.3 Short bones of lower limb	0.000	0.998	0.002
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
D46 Myelodysplastic syndromes	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.002	0.998	0.000
M62.81 Other specified disorders of muscle (Shoulder region)	0.002	0.998	0.000
D46.7 Other myelodysplastic syndromes	0.002	0.998	0.000
S11.8 Open wound of other parts of neck	0.002	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.002	0.998	0.000
S11.1 Open wound involving thyroid gland	0.002	0.998	0.000
S11.0 Open wound involving larynx and trachea	0.002	0.998	0.000
S43.4 Sprain and strain of shoulder joint	0.002	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.002	0.998	0.000
S10.8 Superficial injury of other parts of neck	0.002	0.998	0.000
S10.7 Multiple superficial injuries of neck	0.002	0.998	0.000
S10.0 Contusion of throat	0.002	0.998	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.000	0.998	0.002
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.998	0.002
M50 Cervical disk disorders	0.002	0.998	0.000
J94.1 Fibrothorax	0.000	0.998	0.002
I50.0 Congestive heart failure	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.998	0.002
M62.83 Other specified disorders of muscle (Forearm)	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
S12.11 Fracture of second cervical vertebra (open)	0.002	0.998	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.000	0.998	0.002
Y44.2 Anticoagulants	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.000	0.998	0.002
R57.2 Septic shock	0.000	0.998	0.002
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
D47.4 Osteomyelofibrosis	0.002	0.998	0.000
I70.0 Atherosclerosis of aorta	0.002	0.998	0.000
O73 Retained placenta and membranes, without haemorrhage	0.002	0.998	0.000
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.000	0.998	0.002
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.001	0.998	0.001
S12.91 Fracture of neck, part unspecified (open)	0.002	0.998	0.000
I30.9 Acute pericarditis, unspecified	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.000	0.998	0.002
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
C78.7 Secondary malignant neoplasm of liver	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.002	0.998	0.000
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.002	0.998	0.000
Q51.6 Embryonic cyst of cervix	0.002	0.998	0.000
Q51.5 Agenesis and aplasia of cervix	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.002	0.998	0.000
Q51.0 Agenesis and aplasia of uterus	0.002	0.998	0.000
K75.0 Abscess of liver	0.000	0.998	0.002
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
K70-K77 Diseases of liver	0.000	0.998	0.002
S12.81 Fracture of other parts of neck (open)	0.002	0.998	0.000
S12.80 Fracture of other parts of neck (closed)	0.002	0.998	0.000
D16.5 Lower jaw bone	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
I42.8 Other cardiomyopathies	0.000	0.998	0.002
N85.4 Malposition of uterus	0.000	0.998	0.002
S29 Other and unspecified injuries of thorax	0.002	0.998	0.000
Z20 Contact with and exposure to communicable diseases	0.002	0.998	0.000
S12.01 Fracture of first cervical vertebra (open)	0.001	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
K72.9 Hepatic failure, unspecified	0.000	0.998	0.002
R22.2 Localised swelling, mass and lump, trunk	0.000	0.998	0.002
S11.9 Open wound of neck, part unspecified	0.001	0.998	0.000
J15.1 Pneumonia due to Pseudomonas	0.002	0.998	0.000
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.001	0.998	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.002	0.998	0.000
Z20.1 Contact with and exposure to tuberculosis	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.002	0.998	0.000
S22.50 Flail chest (closed)	0.002	0.998	0.000
J94.2 Haemothorax	0.000	0.998	0.002
M50.8 Other cervical disk disorders	0.002	0.998	0.000
Y60.4 During endoscopic examination	0.002	0.998	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.002	0.998	0.000
I20.8 Other forms of angina pectoris	0.002	0.998	0.000
S20.7 Multiple superficial injuries of thorax	0.002	0.998	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.998	0.000
Y59 Other and unspecified vaccines and biological substances	0.002	0.998	0.000
D16.4 Bones of skull and face	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.998	0.002
M25.43 Effusion of joint (Forearm)	0.000	0.998	0.002
M25.42 Effusion of joint (Upper arm)	0.000	0.998	0.002
M77.91 Enthesopathy, unspecified (Shoulder region)	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.000	0.998	0.002
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.001
Y41.1 Antimycobacterial drugs	0.002	0.998	0.000
Y59.3 Immunoglobulin	0.001	0.998	0.000
I12 Hypertensive renal disease	0.002	0.998	0.000
Z39 Postpartum care and examination	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
S20 Superficial injury of thorax	0.002	0.998	0.000
Z26 Need for immunisation against other single infectious diseases	0.001	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.998	0.000
S20.0 Contusion of breast	0.001	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.001	0.998	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.001	0.998	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.001	0.998	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.000	0.998	0.001
H61.8 Other specified disorders of external ear	0.002	0.998	0.000
N82.0 Vesicovaginal fistula	0.000	0.998	0.002
S29.8 Other specified injuries of thorax	0.001	0.998	0.000
S29.7 Multiple injuries of thorax	0.001	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.001	0.998	0.000
Y54.7 Agents affecting calcification	0.001	0.998	0.000
D16 Benign neoplasm of bone and articular cartilage	0.000	0.998	0.002
I70 Atherosclerosis	0.002	0.998	0.000
K73 Chronic hepatitis, not elsewhere classified	0.000	0.998	0.002
K72 Hepatic failure, not elsewhere classified	0.000	0.998	0.001
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.000	0.998	0.002
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.001	0.998	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.001	0.998	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.001	0.998	0.000
Z20.4 Contact with and exposure to rubella	0.001	0.998	0.000
Z20.3 Contact with and exposure to rabies	0.001	0.998	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.001	0.998	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.001	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
N99-N99 Other disorders of the genitourinary system	0.002	0.998	0.000
D01.2 Rectum	0.001	0.998	0.000
D40.7 Other male genital organs	0.001	0.998	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.001	0.998	0.000
J94 Other pleural conditions	0.000	0.998	0.002
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.001	0.998	0.000
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.998	0.001
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.998	0.002
Z40 Prophylactic surgery	0.000	0.998	0.001
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.001
K25.0 Acute with haemorrhage	0.000	0.998	0.001
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.998	0.001
Q51.8 Other congenital malformations of uterus and cervix	0.001	0.998	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.001	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.001	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.001	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.001	0.998	0.000
Y54.0 Mineralocorticoids	0.001	0.998	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.001	0.998	0.000
Z28 Immunisation not carried out	0.001	0.998	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.001	0.998	0.000
Z25 Need for immunisation against other single viral diseases	0.001	0.998	0.000
Z23 Need for immunisation against single bacterial diseases	0.001	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.001	0.999	0.000
I70.1 Atherosclerosis of renal artery	0.001	0.999	0.000
M25.4 Effusion of joint	0.000	0.999	0.001
N82.3 Fistula of vagina to large intestine	0.000	0.999	0.001
S02.1 Fracture of base of skull	0.000	0.999	0.001
K71 Toxic liver disease	0.000	0.999	0.001
M62.86 Other specified disorders of muscle (Lower leg)	0.001	0.999	0.000
N18.9 Chronic renal failure, unspecified	0.001	0.999	0.000
R44.0 Auditory hallucinations	0.001	0.999	0.000
S22.5 Flail chest	0.001	0.999	0.000
Y54.3 Benzothiadiazine derivatives	0.001	0.999	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
M25.40 Effusion of joint (Multiple sites)	0.000	0.999	0.001
F32.2 Severe depressive episode without psychotic symptoms	0.001	0.999	0.000
R43.8 Other and unspecified disturbances of smell and taste	0.001	0.999	0.000
V18.3 Person injured while boarding or alighting	0.000	0.999	0.001
Y59.9 Vaccine or biological substance, unspecified	0.001	0.999	0.000
Y59.8 Other specified vaccines and biological substances	0.001	0.999	0.000
Y59.2 Protozoal vaccines	0.001	0.999	0.000
Y59.1 Rickettsial vaccines	0.001	0.999	0.000
Y59.0 Viral vaccines	0.001	0.999	0.000
K77 Liver disorders in diseases classified elsewhere	0.000	0.999	0.001
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.999	0.001
D40.1 Testis	0.001	0.999	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.999	0.001
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.001	0.999	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.000	0.999	0.001
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
Z24 Need for immunisation against certain single viral diseases	0.001	0.999	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.999	0.000
M25.44 Effusion of joint (Hand)	0.000	0.999	0.001
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
D16.9 Bone and articular cartilage, unspecified	0.000	0.999	0.001
D16.0 Scapula and long bones of upper limb	0.000	0.999	0.001
K91.1 Postgastric surgery syndromes	0.000	0.999	0.001
M93.9 Osteochondropathy, unspecified	0.000	0.999	0.001
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.999	0.001
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.001	0.999	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.001	0.999	0.000
Z26.0 Need for immunisation against leishmaniasis	0.001	0.999	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
C18.5 Splenic flexure	0.001	0.999	0.000
I70.9 Generalised and unspecified atherosclerosis	0.001	0.999	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.999	0.001
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.999	0.001
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.999	0.001
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.999	0.001
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.999	0.001
S10.9 Superficial injury of neck, part unspecified	0.001	0.999	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.000	0.999	0.001
Y50.9 Central nervous system stimulant, unspecified	0.001	0.999	0.000
Y50.8 Other central nervous system stimulants	0.001	0.999	0.000
Y50.1 Opioid receptor antagonists	0.001	0.999	0.000
Y50.0 Analeptics	0.001	0.999	0.000
Z40.9 Prophylactic surgery, unspecified	0.000	0.999	0.001
D16.8 Pelvic bones, sacrum and coccyx	0.000	0.999	0.001
D16.7 Ribs, sternum and clavicle	0.000	0.999	0.001
D16.6 Vertebral column	0.000	0.999	0.001
H10.8 Other conjunctivitis	0.001	0.999	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.999	0.001
K72.1 Chronic hepatic failure	0.000	0.999	0.001
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.999	0.001
S20.1 Other and unspecified superficial injuries of breast	0.001	0.999	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.000	0.999	0.001
Y41.0 Sulphonamides	0.001	0.999	0.000
D01.3 Anus and anal canal	0.001	0.999	0.000
D40.9 Male genital organ, unspecified	0.001	0.999	0.000
J94.9 Pleural condition, unspecified	0.000	0.999	0.001
J94.0 Chylous effusion	0.000	0.999	0.001
O04 Medical abortion	0.001	0.999	0.000
Y58 Bacterial vaccines	0.001	0.999	0.000
I45.9 Conduction disorder, unspecified	0.000	0.999	0.001
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.999	0.001
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.999	0.001
S20.3 Other superficial injuries of front wall of thorax	0.001	0.999	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.001	0.999	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.001	0.999	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.001	0.999	0.000
Y47.4 Bromine compounds	0.001	0.999	0.000
Y47.3 Paraldehyde	0.001	0.999	0.000
Y47.2 Chloral derivatives	0.001	0.999	0.000
Y47.0 Barbiturates, not elsewhere classified	0.001	0.999	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.001	0.999	0.000
Z23.7 Need for immunisation against pertussis alone	0.001	0.999	0.000
Z23.6 Need for immunisation against diphtheria alone	0.001	0.999	0.000
Z23.5 Need for immunisation against tetanus alone	0.001	0.999	0.000
Z23.4 Need for immunisation against tularaemia	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations