TreeWAS – Variant ID: rs280872

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	1.000	0.000	0.000
H72 Perforation of tympanic membrane	1.000	0.000	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.999	0.001	0.000
H71 Cholesteatoma of middle ear	0.999	0.001	0.000
H65 Nonsuppurative otitis media	0.991	0.009	0.000
Chapter VIII Diseases of the ear and mastoid process	0.976	0.024	0.000
H74 Other disorders of middle ear and mastoid	0.976	0.024	0.000
H60-H62 Diseases of external ear	0.973	0.027	0.000
H60 Otitis externa	0.959	0.041	0.000
H65.4 Other chronic nonsuppurative otitis media	0.926	0.074	0.000
H61 Other disorders of external ear	0.925	0.075	0.000
H60.9 Otitis externa, unspecified	0.919	0.081	0.000
H61.2 Impacted cerumen	0.906	0.094	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.893	0.107	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.891	0.109	0.000
H72.0 Central perforation of tympanic membrane	0.890	0.110	0.000
H72.8 Other perforations of tympanic membrane	0.873	0.127	0.000
H65.2 Chronic serous otitis media	0.871	0.129	0.000
H72.1 Attic perforation of tympanic membrane	0.866	0.134	0.000
H69 Other disorders of Eustachian tube	0.862	0.138	0.000
H70 Mastoiditis and related conditions	0.859	0.141	0.000
H60.4 Cholesteatoma of external ear	0.839	0.161	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.824	0.176	0.000
H60.8 Other otitis externa	0.809	0.191	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.803	0.197	0.000
H61.1 Non-infective disorders of pinna	0.785	0.215	0.000
H65.3 Chronic mucoid otitis media	0.775	0.225	0.000
H74.1 Adhesive middle ear disease	0.762	0.238	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.759	0.241	0.000
H69.9 Eustachian tube disorder, unspecified	0.756	0.244	0.000
H60.3 Other infective otitis externa	0.751	0.249	0.000
H74.0 Tympanosclerosis	0.746	0.254	0.000
H70.8 Other mastoiditis and related conditions	0.740	0.260	0.000
H65.1 Other acute nonsuppurative otitis media	0.737	0.263	0.000
H60.0 Abscess of external ear	0.735	0.265	0.000
H65.0 Acute serous otitis media	0.727	0.273	0.000
H60.2 Malignant otitis externa	0.721	0.279	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.717	0.283	0.000
H68 Eustachian salpingitis and obstruction	0.717	0.283	0.000
H67 Otitis media in diseases classified elsewhere	0.717	0.283	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.697	0.302	0.000
H61.8 Other specified disorders of external ear	0.696	0.304	0.000
H90-H95 Other disorders of ear	0.677	0.323	0.000
H70.9 Mastoiditis, unspecified	0.655	0.345	0.000
H74.4 Polyp of middle ear	0.652	0.347	0.000
H61.3 Acquired stenosis of external ear canal	0.652	0.348	0.000
H69.8 Other specified disorders of Eustachian tube	0.636	0.364	0.000
H80-H83 Diseases of inner ear	0.626	0.374	0.000
H69.0 Patulous Eustachian tube	0.618	0.382	0.000
H70.2 Petrositis	0.616	0.384	0.000
H70.0 Acute mastoiditis	0.616	0.384	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.613	0.387	0.000
H66 Suppurative and unspecified otitis media	0.612	0.388	0.000
H70.1 Chronic mastoiditis	0.611	0.389	0.000
H60.1 Cellulitis of external ear	0.591	0.409	0.000
H61.9 Disorder of external ear, unspecified	0.576	0.424	0.000
H60.5 Acute otitis externa, non-infective	0.568	0.431	0.000
H72.2 Other marginal perforations of tympanic membrane	0.562	0.437	0.000
H80 Otosclerosis	0.559	0.441	0.000
H73 Other disorders of tympanic membrane	0.548	0.452	0.000
H95.1 Other disorders following mastoidectomy	0.530	0.470	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.514	0.486	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.514	0.486	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.514	0.486	0.000
H68.1 Obstruction of Eustachian tube	0.514	0.486	0.000
H68.0 Eustachian salpingitis	0.514	0.486	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.514	0.486	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
H80.9 Otosclerosis, unspecified	0.512	0.488	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.500	0.500	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.500	0.500	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.500	0.500	0.000
H62.2 Otitis externa in mycoses	0.500	0.500	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.500	0.500	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.500	0.500	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.487	0.513	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.486	0.514	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.480	0.519	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.472	0.528	0.000
H93 Other disorders of ear, not elsewhere classified	0.463	0.537	0.000
H66.4 Suppurative otitis media, unspecified	0.458	0.542	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.455	0.544	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.448	0.551	0.000
H91 Other hearing loss	0.448	0.552	0.000
H92 Otalgia and effusion of ear	0.446	0.554	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.440	0.560	0.000
H66.0 Acute suppurative otitis media	0.429	0.571	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.418	0.582	0.000
H66.3 Other chronic suppurative otitis media	0.408	0.592	0.000
H83 Other diseases of inner ear	0.405	0.595	0.000
H80.8 Other otosclerosis	0.401	0.599	0.000
H80.2 Cochlear otosclerosis	0.401	0.599	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.401	0.599	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.401	0.599	0.000
H73.1 Chronic myringitis	0.393	0.607	0.000
H73.0 Acute myringitis	0.393	0.607	0.000
H92.1 Otorrhoea	0.385	0.615	0.000
H93.8 Other specified disorders of ear	0.380	0.619	0.000
H93.9 Disorder of ear, unspecified	0.374	0.626	0.000
H91.8 Other specified hearing loss	0.362	0.638	0.000
H91.1 Presbycusis	0.355	0.645	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.348	0.652	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.348	0.652	0.000
H83.3 Noise effects on inner ear	0.344	0.656	0.000
H93.3 Disorders of acoustic nerve	0.332	0.668	0.000
H93.2 Other abnormal auditory perceptions	0.332	0.668	0.000
H93.0 Degenerative and vascular disorders of ear	0.332	0.668	0.000
H91.0 Ototoxic hearing loss	0.322	0.678	0.000
H92.2 Otorrhagia	0.319	0.681	0.000
H91.3 Deaf mutism, not elsewhere classified	0.319	0.681	0.000
H91.2 Sudden idiopathic hearing loss	0.309	0.691	0.000
H83.9 Disease of inner ear, unspecified	0.303	0.697	0.000
H83.8 Other specified diseases of inner ear	0.290	0.709	0.000
H83.2 Labyrinthine dysfunction	0.290	0.709	0.000
H83.1 Labyrinthine fistula	0.290	0.709	0.000
H90 Conductive and sensorineural hearing loss	0.282	0.718	0.000
H66.9 Otitis media, unspecified	0.272	0.728	0.000
H90.3 Sensorineural hearing loss, bilateral	0.253	0.747	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.241	0.759	0.000
H61.0 Perichondritis of external ear	0.220	0.779	0.001
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.188	0.812	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.180	0.820	0.000
H90.0 Conductive hearing loss, bilateral	0.173	0.827	0.000
H73.8 Other specified disorders of tympanic membrane	0.162	0.837	0.000
H91.9 Hearing loss, unspecified	0.160	0.840	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.158	0.842	0.000
H90.2 Conductive hearing loss, unspecified	0.151	0.849	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.144	0.856	0.000
H90.5 Sensorineural hearing loss, unspecified	0.117	0.882	0.000
H92.0 Otalgia	0.105	0.894	0.001
H93.1 Tinnitus	0.104	0.896	0.000
H81 Disorders of vestibular function	0.089	0.911	0.000
H83.0 Labyrinthitis	0.073	0.927	0.000
H81.8 Other disorders of vestibular function	0.064	0.936	0.000
H81.4 Vertigo of central origin	0.064	0.936	0.000
H81.3 Other peripheral vertigo	0.057	0.943	0.000
H81.1 Benign paroxysmal vertigo	0.054	0.946	0.000
H81.9 Disorder of vestibular function, unspecified	0.051	0.949	0.000
H81.2 Vestibular neuronitis	0.034	0.965	0.001
O36.5 Maternal care for poor foetal growth	0.000	0.971	0.029
H81.0 Meniere's disease	0.025	0.975	0.000
O36 Maternal care for other known or suspected foetal problems	0.000	0.976	0.024
O36.9 Maternal care for foetal problem, unspecified	0.000	0.977	0.023
O36.6 Maternal care for excessive foetal growth	0.000	0.977	0.023
Z88.4 Personal history of allergy to anaesthetic agent	0.000	0.979	0.021
O36.4 Maternal care for intra-uterine death	0.000	0.981	0.019
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.982	0.018
O36.2 Maternal care for hydrops foetalis	0.000	0.982	0.018
O36.1 Maternal care for other isoimmunisation	0.000	0.982	0.018
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.982	0.018
O40 Polyhydramnios	0.000	0.983	0.017
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.984	0.016
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.985	0.015
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.986	0.014
O42 Premature rupture of membranes	0.000	0.986	0.014
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.986	0.014
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.986	0.014
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.986	0.013
O47 False labour	0.000	0.987	0.013
O30 Multiple gestation	0.000	0.987	0.013
O45 Premature separation of placenta [abruptio placentae]	0.000	0.987	0.013
O47.9 False labour, unspecified	0.000	0.987	0.013
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.000	0.987	0.013
O32.8 Maternal care for other malpresentation of foetus	0.000	0.987	0.013
O34.1 Maternal care for tumour of corpus uteri	0.000	0.988	0.012
O32.0 Maternal care for unstable lie	0.000	0.988	0.012
O31 Complications specific to multiple gestation	0.000	0.988	0.012
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.988	0.012
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.988	0.012
O34.8 Maternal care for other abnormalities of pelvic organs	0.000	0.988	0.012
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.988	0.012
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.988	0.012
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.988	0.012
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.988	0.012
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.988	0.012
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.988	0.012
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.988	0.012
O32.4 Maternal care for high head at term	0.000	0.988	0.012
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.988	0.012
O32.9 Maternal care for malpresentation of foetus, unspecified	0.000	0.989	0.011
O32.2 Maternal care for transverse and oblique lie	0.000	0.989	0.011
O44 Placenta praevia	0.000	0.989	0.011
W08.0 Home	0.011	0.989	0.000
O43 Placental disorders	0.000	0.989	0.011
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.989	0.011
O32.6 Maternal care for compound presentation	0.000	0.989	0.011
O34.4 Maternal care for other abnormalities of cervix	0.000	0.989	0.011
O30.0 Twin pregnancy	0.000	0.989	0.011
O48 Prolonged pregnancy	0.000	0.989	0.011
O34.3 Maternal care for cervical incompetence	0.000	0.989	0.010
O33 Maternal care for known or suspected disproportion	0.000	0.989	0.010
O32.3 Maternal care for face, brow and chin presentation	0.000	0.990	0.010
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.000	0.990	0.010
O34.6 Maternal care for abnormality of vagina	0.000	0.990	0.010
O34.5 Maternal care for other abnormalities of gravid uterus	0.000	0.990	0.010
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.990	0.010
O45.9 Premature separation of placenta, unspecified	0.000	0.990	0.010
H04.2 Epiphora	0.010	0.990	0.000
O30.9 Multiple gestation, unspecified	0.000	0.990	0.010
O30.8 Other multiple gestation	0.000	0.990	0.010
O30.2 Quadruplet pregnancy	0.000	0.990	0.010
O45.8 Other premature separation of placenta	0.000	0.990	0.010
O45.0 Premature separation of placenta with coagulation defect	0.000	0.990	0.010
O41 Other disorders of amniotic fluid and membranes	0.000	0.990	0.010
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.991	0.009
O31.8 Other complications specific to multiple gestation	0.000	0.991	0.009
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.991	0.009
O31.0 Papyraceous foetus	0.000	0.991	0.009
O34.7 Maternal care for abnormality of vulva and perineum	0.000	0.991	0.009
O34.0 Maternal care for congenital malformation of uterus	0.000	0.991	0.009
O30.1 Triplet pregnancy	0.000	0.991	0.009
O47.0 False labour before 37 completed weeks of gestation	0.000	0.991	0.009
O43.8 Other placental disorders	0.000	0.991	0.009
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.992	0.008
O43.9 Placental disorder, unspecified	0.000	0.992	0.008
O43.2 Morbidly adherent placenta	0.000	0.992	0.008
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.992	0.008
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.992	0.008
O33.8 Maternal care for disproportion of other origin	0.000	0.992	0.007
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.992	0.007
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.992	0.007
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.992	0.007
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.992	0.007
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.992	0.007
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.992	0.007
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.992	0.007
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.992	0.007
O43.0 Placental transfusion syndromes	0.000	0.992	0.007
D27 Benign neoplasm of ovary	0.007	0.993	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.993	0.007
O41.1 Infection of amniotic sac and membranes	0.000	0.993	0.007
O36.8 Maternal care for other specified foetal problems	0.000	0.993	0.007
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.993	0.007
H04 Disorders of lachrymal system	0.007	0.993	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.000	0.993	0.007
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.993	0.007
O44.1 Placenta praevia with haemorrhage	0.000	0.993	0.007
H04.1 Other disorders of lachrymal gland	0.007	0.993	0.000
O20.0 Threatened abortion	0.000	0.993	0.007
O20 Haemorrhage in early pregnancy	0.000	0.993	0.007
O81.4 Vacuum extractor delivery	0.000	0.993	0.006
Chapter XV Pregnancy, childbirth and the puerperium	0.000	0.994	0.006
O43.1 Malformation of placenta	0.000	0.994	0.006
H04.4 Chronic inflammation of lachrymal passages	0.006	0.994	0.000
O81 Single delivery by forceps and vacuum extractor	0.000	0.994	0.006
O28 Abnormal findings on antenatal screening of mother	0.000	0.994	0.006
O24 Diabetes mellitus in pregnancy	0.000	0.994	0.006
F03 Unspecified dementia	0.000	0.994	0.006
O80-O84 Delivery	0.000	0.994	0.006
O24.4 Diabetes mellitus arising in pregnancy	0.000	0.994	0.006
C78.2 Secondary malignant neoplasm of pleura	0.006	0.994	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.006	0.994	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.994	0.006
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.994	0.006
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.000	0.994	0.006
R06.4 Hyperventilation	0.006	0.994	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
O82 Single delivery by Caesarean section	0.000	0.994	0.006
O46.8 Other antepartum haemorrhage	0.000	0.994	0.005
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.994	0.006
O21 Excessive vomiting in pregnancy	0.000	0.994	0.006
O33.9 Maternal care for disproportion, unspecified	0.001	0.994	0.005
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O46.9 Antepartum haemorrhage, unspecified	0.000	0.995	0.005
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
H04.0 Dacryoadenitis	0.005	0.995	0.000
H04.6 Other changes in lachrymal passages	0.005	0.995	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.995	0.005
O29 Complications of anaesthesia during pregnancy	0.000	0.995	0.005
O25 Malnutrition in pregnancy	0.000	0.995	0.005
E14.9 Without complications	0.005	0.995	0.000
W08 Fall involving other furniture	0.005	0.995	0.000
H02.1 Ectropion of eyelid	0.005	0.995	0.000
O22 Venous complications in pregnancy	0.000	0.995	0.005
H04.9 Disorder of lachrymal system, unspecified	0.005	0.995	0.000
O81.3 Other and unspecified forceps delivery	0.000	0.995	0.005
O82.9 Delivery by Caesarean section, unspecified	0.000	0.995	0.005
O47.1 False labour at or after 37 completed weeks of gestation	0.000	0.995	0.005
H04.8 Other disorders of lachrymal system	0.005	0.995	0.000
O85-O92 Complications predominantly related to the puerperium	0.000	0.995	0.005
O21.0 Mild hyperemesis gravidarum	0.000	0.995	0.005
C77.2 Intra-abdominal lymph nodes	0.005	0.995	0.000
O82.0 Delivery by elective Caesarean section	0.000	0.995	0.005
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
O81.5 Delivery by combination of forceps and vacuum extractor	0.000	0.995	0.005
O81.2 Mid-cavity forceps with rotation	0.000	0.995	0.005
O81.1 Mid-cavity forceps delivery	0.000	0.995	0.005
O24.3 Pre-existing diabetes mellitus, unspecified	0.000	0.995	0.005
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.000	0.995	0.005
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.000	0.995	0.005
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.000	0.995	0.005
O28.8 Other abnormal findings on antenatal screening of mother	0.000	0.995	0.005
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.000	0.995	0.005
O28.4 Abnormal radiological finding on antenatal screening of mother	0.000	0.995	0.005
O28.2 Abnormal cytological finding on antenatal screening of mother	0.000	0.995	0.005
O28.0 Abnormal haematological finding on antenatal screening of mother	0.000	0.995	0.005
O41.0 Oligohydramnios	0.000	0.995	0.004
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.000	0.995	0.005
O84 Multiple delivery	0.000	0.995	0.004
O83 Other assisted single delivery	0.000	0.995	0.004
O23 Infections of genito-urinary tract in pregnancy	0.000	0.995	0.005
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.000	0.995	0.004
O32.1 Maternal care for breech presentation	0.000	0.995	0.005
O82.1 Delivery by emergency Caesarean section	0.000	0.995	0.005
O81.0 Low forceps delivery	0.000	0.995	0.004
O97 Death from sequelae of direct obstetric causes	0.000	0.995	0.004
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.995	0.004
O95 Obstetric death of unspecified cause	0.000	0.995	0.004
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.995	0.004
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O82.8 Other single delivery by Caesarean section	0.000	0.996	0.004
O82.2 Delivery by Caesarean hysterectomy	0.000	0.996	0.004
O24.9 Diabetes mellitus in pregnancy, unspecified	0.000	0.996	0.004
O21.9 Vomiting of pregnancy, unspecified	0.000	0.996	0.004
C77.0 Lymph nodes of head, face and neck	0.004	0.996	0.000
O21.8 Other vomiting complicating pregnancy	0.000	0.996	0.004
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
T42.4 Benzodiazepines	0.000	0.996	0.004
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.996	0.004
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O21.2 Late vomiting of pregnancy	0.000	0.996	0.004
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.000	0.996	0.004
O86 Other puerperal infections	0.000	0.996	0.004
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.000	0.996	0.004
O29.8 Other complications of anaesthesia during pregnancy	0.000	0.996	0.004
O29.6 Failed or difficult intubation during pregnancy	0.000	0.996	0.004
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.000	0.996	0.004
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.000	0.996	0.004
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.000	0.996	0.004
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.000	0.996	0.004
O29.1 Cardiac complications of anaesthesia during pregnancy	0.000	0.996	0.004
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.000	0.996	0.004
Z99.3 Dependence on wheelchair	0.000	0.996	0.004
O22.4 Haemorrhoids in pregnancy	0.000	0.996	0.004
W08.9 Unspecified place	0.004	0.996	0.000
W08.8 Other specified place	0.004	0.996	0.000
W08.7 Farm	0.004	0.996	0.000
W08.6 Industrial and construction area	0.004	0.996	0.000
W08.5 Trade and service area	0.004	0.996	0.000
W08.4 Street and highway	0.004	0.996	0.000
W08.3 Sports and athletics area	0.004	0.996	0.000
W08.2 School, other institution and public administrative area	0.004	0.996	0.000
W08.1 Residential institution	0.004	0.996	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.000	0.996	0.004
O34.2 Maternal care due to uterine scar from previous surgery	0.000	0.996	0.004
O22.9 Venous complication in pregnancy, unspecified	0.000	0.996	0.004
O22.8 Other venous complications in pregnancy	0.000	0.996	0.004
O22.5 Cerebral venous thrombosis in pregnancy	0.000	0.996	0.004
O22.3 Deep phlebothrombosis in pregnancy	0.000	0.996	0.004
O22.2 Superficial thrombophlebitis in pregnancy	0.000	0.996	0.004
O22.1 Genital varices in pregnancy	0.000	0.996	0.004
O87 Venous complications in the puerperium	0.000	0.996	0.004
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.000	0.996	0.004
T90.2 Sequelae of fracture of skull and facial bones	0.004	0.996	0.000
O91 Infections of breast associated with childbirth	0.000	0.996	0.004
O89 Complications of anaesthesia during the puerperium	0.000	0.996	0.004
O88 Obstetric embolism	0.000	0.996	0.004
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.004	0.996	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.004	0.996	0.000
O90 Complications of the puerperium, not elsewhere classified	0.000	0.996	0.004
O83.9 Assisted single delivery, unspecified	0.000	0.996	0.003
O83.8 Other specified assisted single delivery	0.000	0.996	0.003
O83.4 Destructive operation for delivery	0.000	0.996	0.003
O83.3 Delivery of viable foetus in abdominal pregnancy	0.000	0.996	0.003
O83.2 Other manipulation-assisted delivery	0.000	0.996	0.003
O83.1 Other assisted breech delivery	0.000	0.996	0.003
O83.0 Breech extraction	0.000	0.996	0.003
O84.9 Multiple delivery, unspecified	0.000	0.996	0.003
O84.8 Other multiple delivery	0.000	0.996	0.003
O84.2 Multiple delivery, all by Caesarean section	0.000	0.996	0.003
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.000	0.996	0.003
O84.0 Multiple delivery, all spontaneous	0.000	0.996	0.003
C45.9 Mesothelioma, unspecified	0.000	0.996	0.004
O23.3 Infections of other parts of urinary tract in pregnancy	0.000	0.996	0.003
O23.2 Infections of urethra in pregnancy	0.000	0.996	0.003
O23.1 Infections of bladder in pregnancy	0.000	0.996	0.003
O23.0 Infections of kidney in pregnancy	0.000	0.996	0.003
O22.0 Varicose veins of lower extremity in pregnancy	0.000	0.996	0.003
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.996	0.004
L81.4 Other melanin hyperpigmentation	0.004	0.996	0.000
O86.0 Infection of obstetric surgical wound	0.000	0.996	0.003
C45.0 Mesothelioma of pleura	0.000	0.996	0.003
O20.8 Other haemorrhage in early pregnancy	0.000	0.996	0.003
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.000	0.996	0.003
O96.9 Death from unspecified obstetric cause	0.000	0.996	0.003
O96.1 Death from indirect obstetric cause	0.000	0.996	0.003
O96.0 Death from direct obstetric cause	0.000	0.996	0.003
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.996	0.003
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.996	0.003
O97.0 Death from sequelae of direct obstetric cause	0.000	0.996	0.003
T42.1 Iminostilbenes	0.000	0.997	0.003
O87.2 Haemorrhoids in the puerperium	0.000	0.997	0.003
M51.2 Other specified intervertebral disk displacement	0.003	0.997	0.000
C77.8 Lymph nodes of multiple regions	0.003	0.997	0.000
O90.9 Complication of the puerperium, unspecified	0.000	0.997	0.003
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.997	0.003
C45 Mesothelioma	0.000	0.997	0.003
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.997	0.003
O92.2 Other and unspecified disorders of breast associated with childbirth	0.000	0.997	0.003
O26.5 Maternal hypotension syndrome	0.000	0.997	0.003
O26.4 Herpes gestationis	0.000	0.997	0.003
O26.1 Low weight gain in pregnancy	0.000	0.997	0.003
O86.1 Other infection of genital tract following delivery	0.000	0.997	0.003
S50.8 Other superficial injuries of forearm	0.000	0.997	0.003
O86.8 Other specified puerperal infections	0.000	0.997	0.003
O86.3 Other genito-urinary tract infections following delivery	0.000	0.997	0.003
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O23.5 Infections of the genital tract in pregnancy	0.000	0.997	0.003
O26.2 Pregnancy care of habitual aborter	0.000	0.997	0.003
T90 Sequelae of injuries of head	0.003	0.997	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.000	0.997	0.003
O92.7 Other and unspecified disorders of lactation	0.000	0.997	0.003
O92.6 Galactorrhoea	0.000	0.997	0.003
O92.5 Suppressed lactation	0.000	0.997	0.003
O92.4 Hypogalactia	0.000	0.997	0.003
O92.3 Agalactia	0.000	0.997	0.003
O92.1 Cracked nipple associated with childbirth	0.000	0.997	0.003
O92.0 Retracted nipple associated with childbirth	0.000	0.997	0.003
O86.4 Pyrexia of unknown origin following delivery	0.000	0.997	0.003
R25.2 Cramp and spasm	0.000	0.997	0.003
O87.9 Venous complication in the puerperium, unspecified	0.000	0.997	0.003
O87.3 Cerebral venous thrombosis in the puerperium	0.000	0.997	0.003
O87.1 Deep phlebothrombosis in the puerperium	0.000	0.997	0.003
O26.0 Excessive weight gain in pregnancy	0.000	0.997	0.003
S50.0 Contusion of elbow	0.000	0.997	0.003
O86.2 Urinary tract infection following delivery	0.000	0.997	0.003
O23.4 Unspecified infection of urinary tract in pregnancy	0.000	0.997	0.003
O88.8 Other obstetric embolism	0.000	0.997	0.003
O88.3 Obstetric pyaemic and septic embolism	0.000	0.997	0.003
O88.2 Obstetric blood-clot embolism	0.000	0.997	0.003
O88.1 Amniotic fluid embolism	0.000	0.997	0.003
O88.0 Obstetric air embolism	0.000	0.997	0.003
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.000	0.997	0.003
O89.8 Other complications of anaesthesia during the puerperium	0.000	0.997	0.003
O89.6 Failed or difficult intubation during the puerperium	0.000	0.997	0.003
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.000	0.997	0.003
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.000	0.997	0.003
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.000	0.997	0.003
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.000	0.997	0.003
O89.1 Cardiac complications of anaesthesia during the puerperium	0.000	0.997	0.003
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.000	0.997	0.003
O91.2 Nonpurulent mastitis associated with childbirth	0.000	0.997	0.003
O91.1 Abscess of breast associated with childbirth	0.000	0.997	0.003
O91.0 Infection of nipple associated with childbirth	0.000	0.997	0.003
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
O85 Puerperal sepsis	0.000	0.997	0.003
H02.3 Blepharochalasis	0.003	0.997	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
C45.7 Mesothelioma of other sites	0.000	0.997	0.003
O90.5 Postpartum thyroiditis	0.000	0.997	0.003
O90.4 Postpartum acute renal failure	0.000	0.997	0.003
O90.3 Cardiomyopathy in the puerperium	0.000	0.997	0.003
O87.0 Superficial thrombophlebitis in the puerperium	0.000	0.997	0.003
T90.8 Sequelae of other specified injuries of head	0.003	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.003	0.997	0.000
O90.2 Haematoma of obstetric wound	0.000	0.997	0.003
O90.0 Disruption of Caesarean section wound	0.000	0.997	0.003
Z71.3 Dietary counselling and surveillance	0.003	0.997	0.000
O87.8 Other venous complications in the puerperium	0.000	0.997	0.003
C77.9 Lymph node, unspecified	0.003	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.003	0.997	0.000
Z93.5 Cystostomy status	0.000	0.997	0.003
C77.4 Inguinal and lower limb lymph nodes	0.003	0.997	0.000
T90.0 Sequelae of superficial injury of head	0.003	0.997	0.000
H44.0 Purulent endophthalmitis	0.000	0.997	0.003
C45.2 Mesothelioma of pericardium	0.000	0.997	0.003
C45.1 Mesothelioma of peritoneum	0.000	0.997	0.003
R76.8 Other specified abnormal immunological findings in serum	0.000	0.997	0.003
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.997	0.003
T42.3 Barbiturates	0.000	0.997	0.003
T42.2 Succinimides and oxazolidinediones	0.000	0.997	0.003
O90.1 Disruption of perineal obstetric wound	0.000	0.997	0.002
T90.5 Sequelae of intracranial injury	0.003	0.997	0.000
S50 Superficial injury of forearm	0.000	0.997	0.003
O90.8 Other complications of the puerperium, not elsewhere classified	0.000	0.997	0.003
T94.1 Sequelae of injuries, not specified by body region	0.003	0.997	0.000
C77.5 Intrapelvic lymph nodes	0.003	0.997	0.000
T42.0 Hydantoin derivatives	0.000	0.997	0.002
T90.3 Sequelae of injury of cranial nerves	0.002	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.997	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.002	0.998	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.998	0.002
F45.8 Other somatoform disorders	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
T90.1 Sequelae of open wound of head	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations