TreeWAS – Variant ID: rs281377

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K80 Cholelithiasis	0.000	0.000	1.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.000	1.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.000	1.000
K26 Duodenal ulcer	0.000	0.002	0.998
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.002	0.998
K20-K31 Diseases of oesophagus, stomach and duodenum	0.000	0.003	0.997
K29 Gastritis and duodenitis	0.000	0.003	0.997
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.004	0.996
Chapter XI Diseases of the digestive system	0.000	0.005	0.995
K29.5 Chronic gastritis, unspecified	0.000	0.012	0.988
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.012	0.988
K65-K67 Diseases of peritoneum	0.000	0.014	0.986
K66 Other disorders of peritoneum	0.000	0.032	0.968
K66.0 Peritoneal adhesions	0.000	0.043	0.957
K90-K93 Other diseases of the digestive system	0.000	0.043	0.957
K29.0 Acute haemorrhagic gastritis	0.000	0.047	0.953
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.053	0.947
K29.4 Chronic atrophic gastritis	0.000	0.055	0.945
K82 Other diseases of gallbladder	0.000	0.055	0.945
K26.7 Chronic without haemorrhage or perforation	0.000	0.072	0.928
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.081	0.919
K91.4 Colostomy and enterostomy malfunction	0.000	0.095	0.905
K29.3 Chronic superficial gastritis	0.000	0.106	0.894
K82.4 Cholesterolosis of gallbladder	0.000	0.113	0.887
K29.1 Other acute gastritis	0.000	0.120	0.880
K65 Peritonitis	0.000	0.125	0.875
K29.8 Duodenitis	0.000	0.126	0.874
K82.8 Other specified diseases of gallbladder	0.000	0.148	0.852
K66.8 Other specified disorders of peritoneum	0.000	0.156	0.844
K26.1 Acute with perforation	0.000	0.172	0.828
K26.4 Chronic or unspecified with haemorrhage	0.000	0.176	0.824
K65.8 Other peritonitis	0.000	0.188	0.812
K82.9 Disease of gallbladder, unspecified	0.000	0.191	0.809
K26.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.194	0.806
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.197	0.803
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.216	0.784
K26.2 Acute with both haemorrhage and perforation	0.000	0.235	0.765
I10 Essential (primary) hypertension	0.000	0.240	0.760
K80.8 Other cholelithiasis	0.000	0.244	0.756
K25 Gastric ulcer	0.000	0.248	0.752
K27 Peptic ulcer, site unspecified	0.000	0.263	0.737
K23 Disorders of oesophagus in diseases classified elsewhere	0.000	0.278	0.722
K80.3 Calculus of bile duct with cholangitis	0.000	0.283	0.717
K29.9 Gastroduodenitis, unspecified	0.000	0.285	0.715
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.286	0.714
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.293	0.707
K66.9 Disorder of peritoneum, unspecified	0.000	0.294	0.706
K25.3 Acute without haemorrhage or perforation	0.000	0.302	0.698
K91.5 Postcholecystectomy syndrome	0.000	0.304	0.696
K91.1 Postgastric surgery syndromes	0.000	0.308	0.692
K83 Other diseases of biliary tract	0.000	0.311	0.689
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.314	0.686
K28 Gastrojejunal ulcer	0.000	0.354	0.646
K65.9 Peritonitis, unspecified	0.000	0.357	0.642
K26.5 Chronic or unspecified with perforation	0.000	0.358	0.642
K83.1 Obstruction of bile duct	0.000	0.384	0.616
K82.0 Obstruction of gallbladder	0.000	0.397	0.603
K83.0 Cholangitis	0.000	0.397	0.603
K25.5 Chronic or unspecified with perforation	0.000	0.404	0.596
K31 Other diseases of stomach and duodenum	0.000	0.414	0.586
K82.1 Hydrops of gallbladder	0.000	0.414	0.586
K29.2 Alcoholic gastritis	0.000	0.424	0.575
K82.2 Perforation of gallbladder	0.000	0.430	0.570
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.430	0.569
K91.3 Postoperative intestinal obstruction	0.000	0.433	0.567
K25.0 Acute with haemorrhage	0.000	0.436	0.564
K35-K38 Diseases of appendix	0.000	0.439	0.561
K90 Intestinal malabsorption	0.000	0.439	0.561
K25.4 Chronic or unspecified with haemorrhage	0.000	0.443	0.557
K26.0 Acute with haemorrhage	0.000	0.444	0.555
K65.0 Acute peritonitis	0.000	0.454	0.546
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.454	0.546
K27.7 Chronic without haemorrhage or perforation	0.000	0.454	0.545
K82.3 Fistula of gallbladder	0.000	0.454	0.545
K50-K52 Noninfective enteritis and colitis	0.000	0.455	0.545
K25.2 Acute with both haemorrhage and perforation	0.000	0.461	0.539
K25.1 Acute with perforation	0.000	0.461	0.539
K83.9 Disease of biliary tract, unspecified	0.000	0.469	0.531
K27.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.471	0.529
K27.5 Chronic or unspecified with perforation	0.000	0.471	0.529
K27.4 Chronic or unspecified with haemorrhage	0.000	0.471	0.529
K27.2 Acute with both haemorrhage and perforation	0.000	0.471	0.529
K27.1 Acute with perforation	0.000	0.471	0.529
K27.0 Acute with haemorrhage	0.000	0.471	0.529
K23.8 Disorders of oesophagus in other diseases classified elsewhere	0.000	0.475	0.525
K23.1 Megaoesophagus in Chagas' disease	0.000	0.482	0.518
K23.0 Tuberculous oesophagitis	0.000	0.482	0.518
K27.3 Acute without haemorrhage or perforation	0.000	0.484	0.516
K25.7 Chronic without haemorrhage or perforation	0.000	0.484	0.516
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.486	0.514
K50 Crohn's disease [regional enteritis]	0.000	0.487	0.513
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.488	0.512
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.488	0.512
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.000	0.489	0.511
K50.1 Crohn's disease of large intestine	0.000	0.490	0.510
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.493	0.507
K67.3 Tuberculous peritonitis	0.000	0.493	0.507
K67.2 Syphilitic peritonitis	0.000	0.493	0.507
K67.1 Gonococcal peritonitis	0.000	0.493	0.507
K67.0 Chlamydial peritonitis	0.000	0.493	0.507
K26.3 Acute without haemorrhage or perforation	0.000	0.502	0.498
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.504	0.496
K83.5 Biliary cyst	0.000	0.506	0.494
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.508	0.492
K93.1 Megacolon in Chagas' disease	0.000	0.508	0.492
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.508	0.492
K31.4 Gastric diverticulum	0.000	0.517	0.483
K31.8 Other specified diseases of stomach and duodenum	0.000	0.518	0.482
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.522	0.477
K28.7 Chronic without haemorrhage or perforation	0.000	0.537	0.463
K28.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.537	0.463
K28.5 Chronic or unspecified with perforation	0.000	0.537	0.463
K28.4 Chronic or unspecified with haemorrhage	0.000	0.537	0.463
K28.3 Acute without haemorrhage or perforation	0.000	0.537	0.463
K28.2 Acute with both haemorrhage and perforation	0.000	0.537	0.463
K28.1 Acute with perforation	0.000	0.537	0.463
K28.0 Acute with haemorrhage	0.000	0.537	0.463
K92 Other diseases of digestive system	0.000	0.550	0.450
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.556	0.443
K36 Other appendicitis	0.000	0.560	0.440
K31.2 Hourglass stricture and stenosis of stomach	0.000	0.566	0.434
K31.0 Acute dilatation of stomach	0.000	0.573	0.427
K83.2 Perforation of bile duct	0.000	0.579	0.420
K31.3 Pylorospasm, not elsewhere classified	0.000	0.580	0.420
K83.3 Fistula of bile duct	0.000	0.580	0.419
K90.8 Other intestinal malabsorption	0.000	0.593	0.406
K90.3 Pancreatic steatorrhoea	0.000	0.598	0.402
K90.2 Blind loop syndrome, not elsewhere classified	0.000	0.598	0.402
K90.1 Tropical sprue	0.000	0.598	0.402
K31.6 Fistula of stomach and duodenum	0.000	0.599	0.401
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.606	0.394
K83.4 Spasm of sphincter of Oddi	0.000	0.622	0.378
K92.0 Haematemesis	0.000	0.631	0.369
K31.5 Obstruction of duodenum	0.000	0.637	0.363
K37 Unspecified appendicitis	0.000	0.637	0.363
K38 Other diseases of appendix	0.000	0.641	0.359
K50.8 Other Crohn's disease	0.000	0.641	0.358
K70-K77 Diseases of liver	0.000	0.664	0.336
K35 Acute appendicitis	0.000	0.694	0.306
K85 Acute pancreatitis	0.000	0.701	0.299
K90.9 Intestinal malabsorption, unspecified	0.000	0.707	0.293
K31.1 Adult hypertrophic pyloric stenosis	0.000	0.712	0.288
K92.1 Melaena	0.000	0.714	0.286
K38.1 Appendicular concretions	0.000	0.719	0.281
K73 Chronic hepatitis, not elsewhere classified	0.000	0.721	0.279
K38.9 Disease of appendix, unspecified	0.000	0.726	0.274
K74 Fibrosis and cirrhosis of liver	0.000	0.729	0.271
K92.8 Other specified diseases of digestive system	0.000	0.731	0.269
K92.9 Disease of digestive system, unspecified	0.000	0.731	0.269
K70 Alcoholic liver disease	0.000	0.733	0.267
K35.0 Acute appendicitis with generalised peritonitis	0.000	0.734	0.266
K50.9 Crohn's disease, unspecified	0.000	0.736	0.264
K38.0 Hyperplasia of appendix	0.000	0.736	0.264
K66.1 Haemoperitoneum	0.003	0.738	0.259
K38.3 Fistula of appendix	0.000	0.743	0.257
K70.3 Alcoholic cirrhosis of liver	0.000	0.743	0.257
K74.0 Hepatic fibrosis	0.000	0.758	0.242
K77 Liver disorders in diseases classified elsewhere	0.000	0.759	0.241
K86 Other diseases of pancreas	0.000	0.763	0.237
K35.2 Acute appendicitis with generalized peritonitis	0.000	0.764	0.236
K92.2 Gastro-intestinal haemorrhage, unspecified	0.000	0.767	0.233
K73.9 Chronic hepatitis, unspecified	0.000	0.768	0.232
K35.8 Acute appendicitis, other and unspecified	0.000	0.776	0.224
K74.6 Other and unspecified cirrhosis of liver	0.000	0.776	0.224
K85.9 Acute pancreatitis, unspecified	0.000	0.785	0.215
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.790	0.210
K38.2 Diverticulum of appendix	0.000	0.792	0.207
K80.4 Calculus of bile duct with cholecystitis	0.001	0.793	0.206
K50.0 Crohn's disease of small intestine	0.000	0.795	0.205
K85.8 Other acute pancreatitis	0.000	0.796	0.204
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.800	0.200
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.800	0.200
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.800	0.200
K38.8 Other specified diseases of appendix	0.000	0.803	0.197
I83.9 Varicose veins of lower extremities without ulcer or inflammation	0.000	0.805	0.195
K74.4 Secondary biliary cirrhosis	0.000	0.805	0.195
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.805	0.195
K70.1 Alcoholic hepatitis	0.000	0.806	0.194
K35.3 Acute appendicitis with localized peritonitis	0.000	0.807	0.193
K75 Other inflammatory liver diseases	0.000	0.808	0.192
K85.0 Idiopathic acute pancreatitis	0.000	0.808	0.191
K86.8 Other specified diseases of pancreas	0.000	0.809	0.191
K74.1 Hepatic sclerosis	0.000	0.811	0.188
K71 Toxic liver disease	0.000	0.813	0.187
K74.5 Biliary cirrhosis, unspecified	0.000	0.813	0.187
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.814	0.186
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.816	0.184
K85.3 Drug-induced acute pancreatitis	0.000	0.816	0.184
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.819	0.181
M81.9 Osteoporosis, unspecified	0.000	0.820	0.180
K75.0 Abscess of liver	0.000	0.823	0.177
K70.0 Alcoholic fatty liver	0.000	0.826	0.174
K85.1 Biliary acute pancreatitis	0.000	0.826	0.173
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.827	0.173
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.827	0.173
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.827	0.173
K21 Gastro-oesophageal reflux disease	0.000	0.830	0.170
M81.98 Osteoporosis, unspecified (Other)	0.000	0.837	0.163
K70.4 Alcoholic hepatic failure	0.000	0.838	0.162
K86.3 Pseudocyst of pancreas	0.000	0.841	0.159
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.843	0.157
I10-I15 Hypertensive diseases	0.000	0.847	0.153
K83.8 Other specified diseases of biliary tract	0.000	0.857	0.143
K75.2 Nonspecific reactive hepatitis	0.000	0.862	0.137
K75.1 Phlebitis of portal vein	0.000	0.862	0.137
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.864	0.136
K71.9 Toxic liver disease, unspecified	0.000	0.866	0.134
K71.8 Toxic liver disease with other disorders of liver	0.000	0.866	0.134
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.866	0.134
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.866	0.134
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.866	0.134
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.866	0.134
K71.2 Toxic liver disease with acute hepatitis	0.000	0.866	0.134
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.867	0.133
H00.1 Chalazion	0.132	0.868	0.000
I83 Varicose veins of lower extremities	0.000	0.868	0.132
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.868	0.132
K71.0 Toxic liver disease with cholestasis	0.000	0.869	0.131
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.871	0.129
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.871	0.129
K85.2 Alcohol-induced acute pancreatitis	0.001	0.874	0.125
K86.1 Other chronic pancreatitis	0.000	0.876	0.124
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.876	0.123
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.876	0.124
I83.0 Varicose veins of lower extremities with ulcer	0.000	0.877	0.123
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.878	0.122
K72 Hepatic failure, not elsewhere classified	0.000	0.886	0.113
I15 Secondary hypertension	0.000	0.887	0.113
K40-K46 Hernia	0.000	0.887	0.113
K75.9 Inflammatory liver disease, unspecified	0.000	0.888	0.112
I83.2 Varicose veins of lower extremities with both ulcer and inflammation	0.000	0.889	0.111
K75.8 Other specified inflammatory liver diseases	0.000	0.893	0.107
K74.3 Primary biliary cirrhosis	0.000	0.895	0.105
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.001	0.897	0.103
K75.4 Autoimmune hepatitis	0.000	0.897	0.103
I13 Hypertensive heart and renal disease	0.000	0.897	0.103
I11 Hypertensive heart disease	0.000	0.898	0.101
M81 Osteoporosis without pathological fracture	0.000	0.903	0.097
K86.2 Cyst of pancreas	0.000	0.904	0.096
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.906	0.093
I15.9 Seconday hypertension, unspecified	0.000	0.909	0.091
K43 Ventral hernia	0.000	0.915	0.085
K41 Femoral hernia	0.000	0.917	0.083
K52 Other non-infective gastro-enteritis and colitis	0.000	0.918	0.082
I15.8 Other secondary hypertension	0.000	0.918	0.081
I15.2 Hypertension secondary to endocrine disorders	0.000	0.918	0.081
K46 Unspecified abdominal hernia	0.000	0.919	0.081
I15.0 Renovascular hypertension	0.000	0.919	0.081
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.922	0.078
K86.9 Disease of pancreas, unspecified	0.000	0.923	0.077
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.923	0.077
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.924	0.076
E78.0 Pure hypercholesterolaemia	0.000	0.924	0.076
M81.4 Drug-induced osteoporosis	0.000	0.925	0.075
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.926	0.074
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.926	0.074
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.926	0.074
M81.2 Osteoporosis of disuse	0.000	0.926	0.073
I15.1 Hypertension secondary to other renal disorders	0.000	0.927	0.073
K70.9 Alcoholic liver disease, unspecified	0.000	0.927	0.073
M81.0 Postmenopausal osteoporosis	0.000	0.929	0.071
M81.6 Localised osteoporosis [Lequesne]	0.000	0.930	0.070
M81.5 Idiopathic osteoporosis	0.000	0.930	0.070
M81.1 Postoophorectomy osteoporosis	0.000	0.930	0.070
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.931	0.068
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.933	0.066
K81 Cholecystitis	0.000	0.934	0.066
K45 Other abdominal hernia	0.000	0.935	0.065
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.936	0.064
K72.1 Chronic hepatic failure	0.000	0.936	0.063
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.937	0.063
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.937	0.063
M81.8 Other osteoporosis	0.000	0.938	0.062
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.938	0.061
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.938	0.061
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.938	0.061
K43.4 Parastomal hernia with gangrene	0.000	0.938	0.061
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.938	0.061
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.938	0.061
K43.9 Ventral hernia without obstruction or gangrene	0.000	0.939	0.061
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.939	0.061
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.939	0.061
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.940	0.060
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.940	0.060
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.941	0.059
K72.0 Acute and subacute hepatic failure	0.000	0.941	0.058
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.942	0.058
K43.1 Ventral hernia with gangrene	0.000	0.942	0.058
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.943	0.056
K52.1 Toxic gastro-enteritis and colitis	0.000	0.944	0.056
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.945	0.055
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.945	0.055
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.945	0.055
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.945	0.055
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.945	0.055
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.945	0.055
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.945	0.055
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.945	0.055
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.945	0.055
M81.48 Drug-induced osteoporosis (Other)	0.000	0.946	0.054
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.946	0.054
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.946	0.054
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.946	0.054
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.946	0.054
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.946	0.054
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.946	0.054
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.946	0.054
K72.9 Hepatic failure, unspecified	0.000	0.946	0.054
I12 Hypertensive renal disease	0.000	0.946	0.054
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.947	0.053
M81.28 Osteoporosis of disuse (Other)	0.000	0.947	0.053
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.947	0.053
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.947	0.053
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.947	0.053
M81.24 Osteoporosis of disuse (Hand)	0.000	0.947	0.053
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.947	0.053
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.947	0.053
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.947	0.053
K29.6 Other gastritis	0.000	0.948	0.052
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.948	0.051
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.949	0.051
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.949	0.051
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.949	0.051
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.949	0.051
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.949	0.051
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.949	0.051
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.949	0.051
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.949	0.051
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.949	0.051
K76 Other diseases of liver	0.000	0.949	0.051
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.950	0.050
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.950	0.050
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.950	0.050
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.950	0.050
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.950	0.050
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.950	0.050
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.950	0.050
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.950	0.050
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.950	0.050
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.950	0.050
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.950	0.050
M81.58 Idiopathic osteoporosis (Other)	0.000	0.950	0.050
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.950	0.050
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.950	0.050
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.950	0.050
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.950	0.050
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.950	0.050
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.950	0.050
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.950	0.050
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.950	0.050
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.950	0.050
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.950	0.050
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.950	0.050
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.950	0.050
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.950	0.050
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.950	0.050
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.950	0.050
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.950	0.050
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.950	0.050
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.950	0.050
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.950	0.050
J98 Other respiratory disorders	0.000	0.950	0.050
J98.1 Pulmonary collapse	0.000	0.950	0.050
H00 Hordeolum and chalazion	0.049	0.951	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.952	0.048
K44 Diaphragmatic hernia	0.000	0.952	0.048
K45.1 Other specified abdominal hernia with gangrene	0.000	0.953	0.047
J98.8 Other specified respiratory disorders	0.000	0.953	0.047
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.953	0.047
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.953	0.046
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.954	0.046
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.955	0.045
J98.4 Other disorders of lung	0.000	0.955	0.045
M81.89 Other osteoporosis (Site unspecified)	0.000	0.955	0.044
M81.88 Other osteoporosis (Other)	0.000	0.955	0.044
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.955	0.044
M81.86 Other osteoporosis (Lower leg)	0.000	0.955	0.044
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.955	0.044
M81.84 Other osteoporosis (Hand)	0.000	0.955	0.044
M81.83 Other osteoporosis (Forearm)	0.000	0.955	0.044
M81.82 Other osteoporosis (Upper arm)	0.000	0.955	0.044
M81.81 Other osteoporosis (Shoulder region)	0.000	0.955	0.044
K52.3 Indeterminate colitis	0.000	0.957	0.043
J98.2 Interstitial emphysema	0.000	0.958	0.042
K76.8 Other specified diseases of liver	0.000	0.960	0.040
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.961	0.039
J95-J99 Other diseases of the respiratory system	0.000	0.963	0.037
C18.0 Caecum	0.000	0.963	0.037
E53.8 Deficiency of other specified B group vitamins	0.037	0.963	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.000	0.963	0.037
M81.80 Other osteoporosis (Multiple sites)	0.000	0.963	0.036
K76.5 Hepatic veno-occlusive disease	0.000	0.963	0.036
K76.4 Peliosis hepatis	0.000	0.963	0.036
K76.3 Infarction of liver	0.000	0.963	0.036
K76.2 Central haemorrhagic necrosis of liver	0.000	0.963	0.036
J98.3 Compensatory emphysema	0.000	0.964	0.036
K76.1 Chronic passive congestion of liver	0.000	0.965	0.035
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.966	0.034
J99 Respiratory disorders in diseases classified elsewhere	0.000	0.966	0.034
J98.9 Respiratory disorder, unspecified	0.000	0.967	0.033
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.000	0.968	0.032
I12.9 Hypertensive renal disease without renal failure	0.000	0.968	0.032
K44.1 Diaphragmatic hernia with gangrene	0.000	0.968	0.032
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.000	0.968	0.032
H00.0 Hordeolum and other deep inflammation of eyelid	0.031	0.969	0.000
F20.9 Schizophrenia, unspecified	0.000	0.969	0.031
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.969	0.031
K76.6 Portal hypertension	0.000	0.969	0.031
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.970	0.030
K35.9 Acute appendicitis, unspecified	0.000	0.970	0.030
K76.7 Hepatorenal syndrome	0.000	0.970	0.030
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.000	0.970	0.030
K81.8 Other cholecystitis	0.001	0.971	0.029
I83.1 Varicose veins of lower extremities with inflammation	0.000	0.972	0.028
J96 Respiratory failure, not elsewhere classified	0.000	0.973	0.027
K42 Umbilical hernia	0.000	0.973	0.027
J98.6 Disorders of diaphragm	0.000	0.973	0.027
J95.8 Other postprocedural respiratory disorders	0.000	0.974	0.026
J99.8 Respiratory disorders in other diseases classified elsewhere	0.000	0.975	0.025
J99.0 Rheumatoid lung disease	0.000	0.976	0.024
J95.9 Postprocedural respiratory disorder, unspecified	0.000	0.977	0.023
K51 Ulcerative colitis	0.000	0.977	0.023
K81.1 Chronic cholecystitis	0.000	0.977	0.023
F20 Schizophrenia	0.000	0.977	0.023
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.977	0.023
K81.9 Cholecystitis, unspecified	0.000	0.977	0.023
I80 Phlebitis and thrombophlebitis	0.000	0.978	0.022
J95.4 Mendelson's syndrome	0.000	0.978	0.022
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.978	0.022
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.978	0.022
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.978	0.022
J95.5 Postprocedural subglottic stenosis	0.000	0.978	0.021
F20.0 Paranoid schizophrenia	0.000	0.979	0.021
K22 Other diseases of oesophagus	0.000	0.979	0.021
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.000	0.980	0.020
K90.0 Coeliac disease	0.000	0.980	0.020
J95.0 Tracheostomy malfunction	0.000	0.980	0.020
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome	0.000	0.980	0.020
J96.9 Respiratory failure, unspecified	0.000	0.980	0.020
J96.1 Chronic respiratory failure	0.000	0.980	0.020
J96.0 Acute respiratory failure	0.000	0.980	0.020
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.000	0.982	0.018
K40 Inguinal hernia	0.000	0.982	0.018
K42.1 Umbilical hernia with gangrene	0.000	0.982	0.018
K22.5 Diverticulum of oesophagus, acquired	0.000	0.982	0.017
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.983	0.017
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.983	0.017
F20.8 Other schizophrenia	0.000	0.983	0.017
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.983	0.017
F20.6 Simple schizophrenia	0.000	0.983	0.017
F20.4 Postschizophrenic depression	0.000	0.983	0.017
F20.3 Undifferentiated schizophrenia	0.000	0.983	0.017
F20.2 Catatonic schizophrenia	0.000	0.983	0.017
F20.1 Hebephrenic schizophrenia	0.000	0.983	0.017
E53 Deficiency of other B group vitamins	0.017	0.983	0.000
K51.5 Mucosal proctocolitis	0.000	0.984	0.016
E78.2 Mixed hyperlipidaemia	0.000	0.984	0.016
K51.4 Pseudopolyposis of colon	0.000	0.984	0.016
I88 Nonspecific lymphadenitis	0.000	0.984	0.015
F20.5 Residual schizophrenia	0.000	0.985	0.015
M48.07 Spinal stenosis (Lumbosacral region)	0.015	0.985	0.000
J96.09 Acute respiratory failure; Type unspecified	0.000	0.986	0.014
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.000	0.986	0.014
J96.00 Acute respiratory failure; Type I [hypoxic]	0.000	0.986	0.014
J96.19 Chronic respiratory failure; Type unspecified	0.000	0.986	0.014
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.000	0.986	0.014
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.000	0.986	0.014
J96.99 Respiratory failure, unspecified; Type unspecified	0.000	0.986	0.014
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.000	0.986	0.014
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.000	0.986	0.014
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.000	0.986	0.014
K22.4 Dyskinesia of oesophagus	0.000	0.986	0.014
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.987	0.013
K51.2 Ulcerative (chronic) proctitis	0.000	0.987	0.013
C16.9 Stomach, unspecified	0.000	0.987	0.013
K40.1 Bilateral inguinal hernia, with gangrene	0.000	0.987	0.013
E78.8 Other disorders of lipoprotein metabolism	0.000	0.987	0.013
E78.4 Other hyperlipidaemia	0.000	0.987	0.013
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.000	0.987	0.013
K22.3 Perforation of oesophagus	0.000	0.987	0.013
I86 Varicose veins of other sites	0.000	0.987	0.013
I88.8 Other nonspecific lymphadenitis	0.000	0.987	0.012
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.987	0.012
E78.6 Lipoprotein deficiency	0.000	0.988	0.012
E53.1 Pyridoxine deficiency	0.012	0.988	0.000
E53.0 Riboflavin deficiency	0.012	0.988	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.988	0.012
I87 Other disorders of veins	0.000	0.988	0.012
I88.9 Nonspecific lymphadenitis, unspecified	0.000	0.988	0.012
E78.3 Hyperchylomicronaemia	0.000	0.988	0.012
E53.9 Vitamin B deficiency, unspecified	0.012	0.988	0.000
I85 Oesophageal varices	0.000	0.988	0.012
I88.1 Chronic lymphadenitis, except mesenteric	0.000	0.989	0.011
K51.8 Other ulcerative colitis	0.000	0.989	0.011
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.989	0.011
I86.4 Gastric varices	0.000	0.989	0.011
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.989	0.011
I87.2 Venous insufficiency (chronic) (peripheral)	0.000	0.989	0.011
I89.1 Lymphangitis	0.000	0.989	0.011
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.000	0.989	0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations